Analytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and Processes
Cerebrovascular CirculationBlood CirculationExtracorporeal CirculationPulmonary Circulation
Cerebrovascular Circulation
The circulation of blood through the BLOOD VESSELS of the BRAIN.
Blood Circulation
The movement of the BLOOD as it is pumped through the CARDIOVASCULAR SYSTEM.
Extracorporeal Circulation
Diversion of blood flow through a circuit located outside the body but continuous with the bodily circulation.
Pulmonary Circulation
The circulation of the BLOOD through the LUNGS.

The functional anatomy of the normal human auditory system: responses to 0.5 and 4.0 kHz tones at varied intensities. (1/8163)

Most functional imaging studies of the auditory system have employed complex stimuli. We used positron emission tomography to map neural responses to 0.5 and 4.0 kHz sine-wave tones presented to the right ear at 30, 50, 70 and 90 dB HL and found activation in a complex neural network of elements traditionally associated with the auditory system as well as non-traditional sites such as the posterior cingulate cortex. Cingulate activity was maximal at low stimulus intensities, suggesting that it may function as a gain control center. In the right temporal lobe, the location of the maximal response varied with the intensity, but not with the frequency of the stimuli. In the left temporal lobe, there was evidence for tonotopic organization: a site lateral to the left primary auditory cortex was activated equally by both tones while a second site in primary auditory cortex was more responsive to the higher frequency. Infratentorial activations were contralateral to the stimulated ear and included the lateral cerebellum, the lateral pontine tegmentum, the midbrain and the medial geniculate. Contrary to predictions based on cochlear membrane mechanics, at each intensity, 4.0 kHz stimuli were more potent activators of the brain than the 0.5 kHz stimuli.  (+info)

Loss of endothelium and receptor-mediated dilation in pial arterioles of rats fed a short-term high salt diet. (2/8163)

A high salt diet often is regarded as an accessory risk factor in hypertension, coincidental to the deleterious effect of high blood pressure on vasodilator function. The aim of this study was to determine whether short-term ingestion of a high salt diet per se impairs vasodilator function in the cerebral circulation independent of blood pressure changes. Adult Sprague-Dawley rats were fed a normal salt (0.8%) or high salt (4%) diet for 3 days. Mean arterial pressures were similar in the normal and high salt groups (123+/-2 and 125+/-2 mm Hg, respectively). Subsequently, the responses of the in situ pial arterioles to acetylcholine, iloprost, and sodium nitroprusside were determined in cranial windows using intravital videomicroscopy. Pial arterioles of rats fed normal and high salt diets showed similar resting diameters of 69+/-2 and 72+/-3 microm, respectively, but their reactivity patterns to vasodilator stimuli were markedly different. Arterioles of rats fed a normal salt diet dilated progressively up to 17+/-3% in response to the endothelium-dependent agent acetylcholine (10(-9) to 10(-6) mol/L) and dilated by 22+/-2% in response to the prostaglandin I2 receptor agonist iloprost (3x10(-11) mol/L). In contrast, pial arterioles of rats fed a high salt diet constricted by 4+/-3% and 8+/-2% in response to acetylcholine and iloprost, respectively. Sodium nitroprusside (10(-6) mol/L), a nitric oxide donor, dilated pial arterioles of rats fed low and high salt diets by a similar amount (19+/-3% and 16+/-2%, respectively), suggesting that signaling mechanisms for dilation distal to the vascular smooth muscle membrane were intact after high salt intake. These results provide the first evidence that the short-term ingestion of a high salt diet may severely impair the vasodilator function of the in situ cerebral microcirculation independent of blood pressure elevation.  (+info)

Parametric mapping of cerebral blood flow deficits in Alzheimer's disease: a SPECT study using HMPAO and image standardization technique. (3/8163)

This study assessed the accuracy and reliability of Automated Image Registration (AIR) for standardization of brain SPECT images of patients with Alzheimer's disease (AD). Standardized cerebral blood flow (CBF) images of patients with AD and control subjects were then used for group comparison and covariance analyses. METHODS: Thirteen patients with AD at an early stage (age 69.8+/-7.1 y, Clinical Dementia Rating Score 0.5-1.0, Mini-Mental State Examination score 19-23) and 20 age-matched normal subjects (age 69.5+/-8.3 y) participated in this study. 99mTc-hexamethyl propylenamine oxime (HMPAO) brain SPECT and CT scans were acquired for each subject. SPECT images were transformed to a standard size and shape with the help of AIR. Accuracy of AIR for spatial normalization was evaluated by an index calculated on SPECT images. Anatomical variability of standardized target images was evaluated by measurements on corresponding CT scans, spatially normalized using transformations established by the SPECT images. Realigned brain SPECT images of patients and controls were used for group comparison with the help of statistical parameter mapping. Significant differences were displayed on the respective voxel to generate three-dimensional Z maps. CT scans of individual subjects were evaluated by a computer program for brain atrophy. Voxel-based covariance analysis was performed on standardized images with ages and atrophy indices as independent variables. RESULTS: Inaccuracy assessed by functional data was 2.3%. The maximum anatomical variability was 4.9 mm after standardization. Z maps showed significantly decreased regional CBF (rCBF) in the frontal, parietal and temporal regions in the patient group (P < 0.001). Covariance analysis revealed that the effects of aging on rCBF were more pronounced compared with atrophy, especially in intact cortical areas at an early stage of AD. Decrease in rCBF was partly due to senility and atrophy, however these two factors cannot explain all the deficits. CONCLUSION: AIR can transform SPECT images of AD patients with acceptable accuracy without any need for corresponding structural images. The frontal regions of the brain, in addition to parietal and temporal lobes, may show reduced CBF in patients with AD even at an early stage of dementia. The reduced rCBF in the cortical regions cannot be explained entirely by advanced atrophy and fast aging process.  (+info)

Nitric oxide modulates endothelin 1-induced Ca2+ mobilization and cytoskeletal F-actin filaments in human cerebromicrovascular endothelial cells. (4/8163)

A functional interrelation between nitric oxide (NO), the endothelial-derived vasodilating factor, and endothelin 1 (ET-1), the potent vasoconstrictive peptide, was investigated in microvascular endothelium of human brain. Nor-1 dose-dependently decreased the ET-1-stimulated mobilization of Ca2+. This response was mimicked with cGMP and abrogated by inhibitors of guanylyl cyclase or cGMP-dependent protein kinase G. These findings indicate that NO and ET-1 interactions involved in modulation of intracellular Ca2+ are mediated by cGMP/protein kinase G. In addition, Nor-1-mediated effects were associated with rearrangements of cytoskeleton F-actin filaments. The results suggest mechanisms by which NO-ET-1 interactions may contribute to regulation of microvascular function.  (+info)

Expression of neuropeptide Y receptors mRNA and protein in human brain vessels and cerebromicrovascular cells in culture. (5/8163)

Neuropeptide Y (NPY) has been suggested as an important regulator of CBF. However, except for the presence of Y1 receptors in large cerebral arteries, little is known about its possible sites of action on brain vessels. In this study, we sought to identify the NPY receptors present in the human cerebrovascular bed. Specific Y1 receptor binding sites, localized on the smooth muscle of human pial vessels and potently competed by NPY, polypeptide YY (PYY), and the selective Y1 receptor antagonist BIBP 3226, were identified by quantitative radioautography of the Y1 radioligand [125I]-[Leu31, Pro34]-PYY. In contrast, no specific binding of the Y2-([125I]-PYY3-36) and Y4/Y5-(125I-human pancreatic polypeptide [hPP]) radioligands could be detected. By in situ hybridization, expression of Y1 receptor mRNA was restricted to the smooth muscle layer of pial vessels, whereas no specific signals were detected for either Y2, Y4, or Y5 receptors. Similarly, using reverse transcriptase-polymerase chain reaction (RT-PCR), mRNA for Y1 but not Y2, Y4, or Y5 receptors was consistently detected in isolated human pial vessels, intracortical microvessels, and capillaries. In human brain microvascular cells in culture, PCR products for the Y1 receptors were exclusively found in the smooth muscle cells. In cultures of human brain astrocytes, a cell type that associates intimately with brain microvessels, PCR products for Y1, Y2, and Y4 but not Y5 receptors were identified. Finally, NPY significantly inhibited the forskolin-induced cAMP production in smooth muscle but not in endothelial cell cultures. We conclude that smooth muscle Y1 receptors are the primary if not exclusive NPY receptors associated with human brain extraparenchymal and intraparenchymal blood vessels, where they most likely mediate cerebral vasoconstriction.  (+info)

Disrupted temporal lobe connections in semantic dementia. (6/8163)

Semantic dementia refers to the variant of frontotemporal dementia in which there is progressive semantic deterioration and anomia in the face of relative preservation of other language and cognitive functions. Structural imaging and SPECT studies of such patients have suggested that the site of damage, and by inference the region critical to semantic processing, is the anterolateral temporal lobe, especially on the left. Recent functional imaging studies of normal participants have revealed a network of areas involved in semantic tasks. The present study used PET to examine the consequences of focal damage to the anterolateral temporal cortex for the operation of this semantic network. We measured PET activation associated with a semantic decision task relative to a visual decision task in four patients with semantic dementia compared with six age-matched normal controls. Normals activated a network of regions consistent with previous studies. The patients activated some areas consistently with the normals, including some regions of significant atrophy, but showed substantially reduced activity particularly in the left posterior inferior temporal gyrus (iTG) (Brodmann area 37/19). Voxel-based morphometry, used to identify the regions of structural deficit, revealed significant anterolateral temporal atrophy (especially on the left), but no significant structural damage to the posterior inferior temporal lobe. Other evidence suggests that the left posterior iTG is critically involved in lexical-phonological retrieval: the lack of activation here is consistent with the observation that these patients are all anomic. We conclude that changes in activity in regions distant from the patients' structural damage support the argument that their prominent anomia is due to disrupted temporal lobe connections.  (+info)

The cerebral haemodynamics of music perception. A transcranial Doppler sonography study. (7/8163)

The perception of music has been investigated by several neurophysiological and neuroimaging methods. Results from these studies suggest a right hemisphere dominance for non-musicians and a possible left hemisphere dominance for musicians. However, inconsistent results have been obtained, and not all variables have been controlled by the different methods. We performed a study with functional transcranial Doppler sonography (fTCD) of the middle cerebral artery to evaluate changes in cerebral blood flow velocity (CBFV) during different periods of music perception. Twenty-four healthy right-handed subjects were enrolled and examined during rest and during listening to periods of music with predominant language, rhythm and harmony content. The gender, musical experience and mode of listening of the subjects were chosen as independent factors; the type of music was included as the variable in repeated measurements. We observed a significant increase of CBFV in the right hemisphere in non-musicians during harmony perception but not during rhythm perception; this effect was more pronounced in females. Language perception was lateralized to the left hemisphere in all subject groups. Musicians showed increased CBFV values in the left hemisphere which were independent of the type of stimulus, and background listeners showed increased CBFV values during harmony perception in the right hemisphere which were independent of their musical experience. The time taken to reach the peak of CBFV was significantly longer in non-musicians when compared with musicians during rhythm and harmony perception. Pulse rates were significantly decreased in non-musicians during harmony perception, probably due to a specific relaxation effect in this subgroup. The resistance index did not show any significant differences, suggesting only regional changes of small resistance vessels but not of large arteries. Our fTCD study confirms previous findings of right hemisphere lateralization for harmony perception in non-musicians. In addition, we showed that this effect is more pronounced in female subjects and in background listeners and that the lateralization is delayed in non-musicians compared with musicians for the perception of rhythm and harmony stimuli. Our data suggest that musicians and non-musicians have different strategies to lateralize musical stimuli, with a delayed but marked right hemisphere lateralization during harmony perception in non-musicians and an attentive mode of listening contributing to a left hemisphere lateralization in musicians.  (+info)

Correlation of regional cerebral blood flow and change of plasma sodium concentration during genesis and satiation of thirst. (8/8163)

Positron emission tomography studies were conducted during genesis of moderate thirst by rapid i.v. infusion of hypertonic saline (0.51 M) and after satiation of thirst by drinking water. The correlation of regional cerebral blood flow with the change in the plasma Na concentration showed a significant group of cerebral activations in the anterior cingulate region and also a site in the middle temporal gyrus and in the periaqueductal gray. Strongest deactivations occurred in the parahippocampal and frontal gyri. The data are consistent with an important role of the anterior cingulate in the genesis of thirst.  (+info)

Temporal lobe seizure interhemispheric propagation time depends on nonepileptic cortical cerebral blood flow<...
TY - JOUR. T1 - Temporal lobe seizure interhemispheric propagation time depends on nonepileptic cortical cerebral blood flow. AU - Weinand, M. E.. AU - Labiner, D. M.. AU - Ahern, G. L.. PY - 2001/3/24. Y1 - 2001/3/24. N2 - In some patients with epilepsy, activation of eloquent cortex using various forms of environmental stimulation and mental activity may induce seizures. The increased neuronal activity resulting from cortical stimulation may be associated with increased regional cerebral blood flow. The vascular steal theory of temporal lobe epilepsy suggests that as nonepileptogenic cortical cerebral blood flow (CBFn) increases, temporal lobe epileptogenicity increases as a result, in part, of decreasing interhemispheric propagation time (IHPT). Recently, IHPT has been shown to be a quantitative electrocorticographic measure of temporal lobe epileptogenicity. In the current study, long-term combined subdural-EEG and surface cortical cerebral blood flow (CBF) monitoring was performed to test ...
https://arizona.pure.elsevier.com/en/publications/temporal-lobe-seizure-interhemispheric-propagation-time-depends-o
The influence of hypoglycaemia on regional cerebral blood flow and cerebral volume in type 1 (insulin-dependent) diabetes...The influence of hypoglycaemia on regional cerebral blood flow and cerebral volume in type 1 (insulin-dependent) diabetes...
article{3b545620-2f5d-4405-9964-2753884aaa8d, abstract = {The effect of moderate hypoglycaemia (venous blood glucose 2.0 +/- 0.2 mmol/l; mean +/- SD) on regional cerebral blood flow and cerebral volume was studied in a group of ten right-handed patients with Type 1 (insulin-dependent) diabetes mellitus (age 26.0 +/- 2.4 years, duration 18.4 +/- 3.8 years) using an intravenous Xenon 133 single photon emission computed tomography technique. After 10 min of hypoglycaemia, global cerebral blood flow had increased to 55.8 +/- 4.5 ml.100 g-1.min-1 compared to the initial normoglycaemic flow of 49.5 +/- 3.7 ml.100 g-1.min-1 (p < 0.01). A further increase in global cerebral blood flow to 59.5 +/- 4.5 ml.100 g-1.min-1 (p < 0.05) occurred 15 min after normalization of the blood glucose level. The global cerebral blood flow change from before hypoglycaemia to after recovery was inversely related to the initial glucose level. No change in the relative distribution of the regional cerebral blood flow ...
https://lup.lub.lu.se/search/publication/1107697
Effects of Visual Deprivation on Regional Cerebral Blood Flow Velocity and Neurovascular Coupling | JOV | ARVO JournalsEffects of Visual Deprivation on Regional Cerebral Blood Flow Velocity and Neurovascular Coupling | JOV | ARVO Journals
Recently, short-term visual deprivation has been shown to affect a variety of non-visual processes and regional cortical activity (Sathian & Zangaladze, 2001). Surprisingly, very little is known about how such visual deprivation impacts regional cerebral blood flow velocity (CBFv) or its adaptation with the underlying neuronal activity (i.e., neurovascular coupling). The current study sought to investigate the effects of short-term (two-hour) visual deprivation on regional CBFv and neurovascular coupling. CBFv (transcranial Doppler ultrasound) was measured concurrently in the posterior cerebral artery (PCA) and the middle cerebral artery (MCA). Neurovascular coupling was assessed using established methods, consisting of two minutes of baseline (eyes closed and reading), five cycles of 40 seconds reading - 20 seconds eyes-closed (primary protocol), and five cycles of 40 seconds eyes-moving - 20 seconds eyes-closed (secondary protocol). Neurovascular coupling, using both protocols, was collected ...
http://jov.arvojournals.org/article.aspx?articleid=2139249
Lack of effect of antenatal indomethacin on fetal cerebral blood flow<...Lack of effect of antenatal indomethacin on fetal cerebral blood flow<...
TY - JOUR. T1 - Lack of effect of antenatal indomethacin on fetal cerebral blood flow. AU - Parilla, B. V.. AU - Tamura, R. K.. AU - Cohen, L. S.. AU - Clark, E.. AU - Hess, L. W.. AU - Rightmire, D. A.. AU - Saade, G.. PY - 1997/1/1. Y1 - 1997/1/1. N2 - OBJECTIVE: Our purpose was to investigate fetal cerebral blood flow and the incidence of intraventricular hemorrhage in patients undergoing tocolysis with either indomethacin or magnesium sulfate at ,30 weeks gestation. STUDY DESIGN: Consenting patients at ,30 weeks gestation with preterm labor were randomized to receive indomethacin or magnesium sulfate tocolysis. Magnesium sulfate was administered intravenously with an 8 gm loading dose given over the first hour, 4 gm over the second hour, and then a maintenance infusion of 2.5 gm per hour. The infusion was continued for approximately 12 hours after the cessation of uterine contractions. Patients randomized to receive indomethacin were given an initial dose of 50 to 100 mg orally or per ...
https://researchexperts.utmb.edu/en/publications/lack-of-effect-of-antenatal-indomethacin-on-fetal-cerebral-blood-
REGIONAL CEREBRAL BLOOD FLOW FOLLOWING RESUSCITATION FROM HEMORRHAGIC SHOCK IN DOGS WITH A SUBDURAL MASS | Anesthesiology | ASA...REGIONAL CEREBRAL BLOOD FLOW FOLLOWING RESUSCITATION FROM HEMORRHAGIC SHOCK IN DOGS WITH A SUBDURAL MASS | Anesthesiology | ASA...
J. M. Whitley, D. S. Prough, A. K. Lamb, D. D. Deal, D. S. DeWitt; REGIONAL CEREBRAL BLOOD FLOW FOLLOWING RESUSCITATION FROM HEMORRHAGIC SHOCK IN DOGS WITH A SUBDURAL MASS. Anesthesiology 1988;69(3A):A539. Download citation file:. ...
http://anesthesiology.pubs.asahq.org/article.aspx?articleid=1964140
Effects of psychotherapy on regional cerebral blood flow during trauma imagery in patients with post-traumatic stress disorder:...
TY - JOUR. T1 - Effects of psychotherapy on regional cerebral blood flow during trauma imagery in patients with post-traumatic stress disorder: a randomized clinical trial. AU - Lindauer, R.J.L.. AU - Booij, J.. AU - Habraken, J.B.A.. AU - van Meijel, E.P.M.. AU - Uylings, H.B.M.. AU - Olff, M.. AU - Carlier, I.V.E.. AU - den Heeten, G.J.. AU - Eck-Smit, B.L.F.. AU - Gersons, B.P.R.. PY - 2008. Y1 - 2008. U2 - 10.1017/S0033291707001432. DO - 10.1017/S0033291707001432. M3 - Article. C2 - 17803835. VL - 38. SP - 543. EP - 554. JO - Psychological Medicine. JF - Psychological Medicine. SN - 0033-2917. IS - 4. ER - ...
https://research.vumc.nl/en/publications/effects-of-psychotherapy-on-regional-cerebral-blood-flow-during-t
RWJMS - Departments and Institutes - Physiology and Biophysics
Chi, O.Z., C. Hunter, X. Liu, S.K. Chokshi and H.R. Weiss. Effects of fentanyl pretreatment on regional cerebral blood flow in focal cerebral ischemia in rats. Pharmacol. 85:153-157, 2010.. Chi, O.Z., C. Hunter, X. Liu and H.R. Weiss. The effects of isoflurane pretreatment on cerebral blood flow, capillary permeability, and oxygen consumption in focal cerebral ischemia in rats. Anesth. Analg. 110:1412-1418, 2010.. Liu, X., C. Hunter, H.R. Weiss and O.Z. Chi. Effects of blockade of ionotropic glutamate receptors on blood-brain barrier disruption in focal cerebral ischemia. Neurol. Sci. 31:699-703, 2010.. Chi, O.Z., C. Hunter, X. Liu, Y. Chi and H.R. Weiss. Effects of GABAA receptor blockade on regional cerebral blood flow and blood-brain barrier disruption in focal cerebral ischemia. J. Neurol. Sci. 301:66-70, 2011.. Chi, O.Z., C. Hunter, X. Liu and H.R. Weiss. The effects of dexmedetomidine on regional cerebral blood flow and oxygen consumption during severe hemorrhagic hypotension in rats. ...
http://www.rwjms.rutgers.edu/neuroscience/faculty/Weiss.html
Cerebral blood flow autoregulation is impaired in schizophrenia: A pilot study<...
TY - JOUR. T1 - Cerebral blood flow autoregulation is impaired in schizophrenia. T2 - A pilot study. AU - Ku, Hsiao Lun. AU - Wang, Jiunn Kae. AU - Lee, Hsin-Chien. AU - Lane, Timothy Joseph. AU - Liu, I-Chao. AU - Chen, Yung Chan. AU - Lee, Yao Tung. AU - Lin, I Cheng. AU - Lin, Chia Pei. AU - Hu, Chaur-Jong. AU - Chi, Nai-Fang. PY - 2017/10. Y1 - 2017/10. N2 - Patients with schizophrenia have a higher risk of cardiovascular diseases and higher mortality from them than does the general population; however, the underlying mechanism remains unclear. Impaired cerebral autoregulation is associated with cerebrovascular diseases and their mortality. Increased or decreased cerebral blood flow in different brain regions has been reported in patients with schizophrenia, which implies impaired cerebral autoregulation. This study investigated the cerebral autoregulation in 21 patients with schizophrenia and 23 age- and sex-matched healthy controls. None of the participants had a history of cardiovascular ...
https://tmu.pure.elsevier.com/zh/publications/cerebral-blood-flow-autoregulation-is-impaired-in-schizophrenia-a
Arterial spin labeling imaging reveals widespread and Aβ-independent reductions in cerebral blood flow in elderly...Arterial spin labeling imaging reveals widespread and Aβ-independent reductions in cerebral blood flow in elderly...
Changes in cerebral blood flow are an essential feature of Alzheimers disease and have been linked to apolipoprotein E-genotype and cerebral amyloid-deposition. These factors could be interdependent or influence cerebral blood flow via different mechanisms. We examined apolipoprotein E-genotype, amyloid beta-deposition, and cerebral blood flow in amnestic mild cognitive impairment using pseudo-continuous arterial spin labeling MRI in 27 cognitively normal elderly and 16 amnestic mild cognitive impairment participants. Subjects underwent Pittsburgh Compound B (PiB) positron emission tomography and apolipoprotein E-genotyping. Global cerebral blood flow was lower in apolipoprotein E ɛ4-allele carriers (apolipoprotein E4+) than in apolipoprotein E4- across all subjects (including cognitively normal participants) and within the group of cognitively normal elderly. Global cerebral blood flow was lower in subjects with mild cognitive impairment compared with cognitively normal. Subjects with ...
http://www.zora.uzh.ch/id/eprint/117708/
Frontiers | Glutamate Levels and Resting Cerebral Blood Flow in Anterior Cingulate Cortex Are Associated at Rest and...Frontiers | Glutamate Levels and Resting Cerebral Blood Flow in Anterior Cingulate Cortex Are Associated at Rest and...
Progressive loss of brain tissue is seen in some patients with schizophrenia and might be caused by increased levels of glutamate and resting cerebral blood flow (rCBF) alterations. Animal studies suggest that normalization of glutamate levels decreases rCBF and prevents structural changes in hippocampus. However, the relationship between glutamate and rCBF in anterior cingulate cortex (ACC) of humans has not been studied in the absence of antipsychotics and illness chronicity. Ketamine is a non-competitive N-Methyl-D-Aspartate receptor antagonist that transiently induces schizophrenia-like symptoms and neurobiological disturbances in healthy volunteers (HV). Here, we used S-ketamine challenge to assess if glutamate levels were associated with rCBF in anterior cingulate cortex (ACC) in 25 male HV. Second, we explored if S-ketamine changed neural activity as reflected by rCBF alterations in thalamus and accumbens that are connected with ACC. Glutamatergic metabolites were measured in ACC with magnetic
https://www.frontiersin.org/articles/10.3389/fpsyt.2018.00022/full
Cerebrovascular circulation: Definition with Cerebrovascular circulation Pictures and PhotosCerebrovascular circulation: Definition with Cerebrovascular circulation Pictures and Photos
Definition of Cerebrovascular circulation with photos and pictures, translations, sample usage, and additional links for more information.
http://lexic.us/definition-of/cerebrovascular_circulation
Cerebral blood flow and neuropsychological asymmetries in unilateral stroke. | StrokeCerebral blood flow and neuropsychological asymmetries in unilateral stroke. | Stroke
This study sought to determine the degree of agreement between asymmetries of neuropsychological functioning and nine methods of quantifying asymmetries of regional cerebral blood flow.. The regional cerebral blood flow methods combined three markers of cerebral blood flow asymmetry (percent hemispheric difference, maximum percent probe-pair asymmetry, and number of probe-pair asymmetries) with three indexes of regional cerebral blood flow (fast compartment flow, initial slope index, and initial slope). Eleven patients with left hemispheric ischemic strokes and 13 with right hemispheric ischemic strokes were studied with the xenon-133 inhalation technique and neuropsychological tests.. Blind clinical judgments of neuropsychological asymmetry significantly correlated with all nine methods of cerebral blood flow asymmetry determination; correlations ranged from -0.42 to -0.77. Clinical judgment of asymmetry of neuropsychological functioning accurately predicted the hemisphere of lower flow in ...
http://stroke.ahajournals.org/content/22/11/1384
Frontotemporal cerebral blood flow change during executive and declarative memory tasks in schizophrenia: A positron emission...
TY - JOUR. T1 - Frontotemporal cerebral blood flow change during executive and declarative memory tasks in schizophrenia. T2 - A positron emission tomography study. AU - Ragland, John D. AU - Gur, Ruben C.. AU - Glahn, David C.. AU - Censits, David M.. AU - Smith, Robin J.. AU - Lazarev, Mark G.. AU - Alavi, Abass. AU - Gur, Raquel E.. PY - 1998/7. Y1 - 1998/7. N2 - Schizophrenia affects prefrontal and temporal-limbic networks. These regions were examined by contrasting regional cerebral blood flow (rCBF) during executive (Wisconsin Card Sorting Test [WCST]), and declarative memory tasks (Paired Associate Recognition Test [PART]). The tasks, and a resting baseline, were administered to 15 patients with schizophrenia and 15 healthy controls during 10 min positron emission tomography 15O-water measures of rCBF. Patients were worse on both tasks. Controls activated inferior frontal, occipitotemporal, and temporal pole regions for both tasks. Similar results were obtained for controls matched to ...
https://ucdavis.pure.elsevier.com/en/publications/frontotemporal-cerebral-blood-flow-change-during-executive-and-de
Gray matter blood flow change is unevenly distributed during moderate isocapnic hypoxia in humansGray matter blood flow change is unevenly distributed during moderate isocapnic hypoxia in humans
Hypoxia increases cerebral blood flow (CBF), but it is unknown whether this increase is uniform across all brain regions. We used H215O positron emission tomography imaging to measure absolute blood flow in 50 regions of interest across the human brain (n = 5) during normoxia and moderate hypoxia. PCO2 was kept constant (44 Torr) throughout the study to avoid decreases in CBF associated with the hypocapnia that normally occurs with hypoxia. Breathing was controlled by mechanical ventilation. During hypoxia (inspired PO2 = 70 Torr), mean end-tidal PO2 fell to 45 ᠶ.3 Torr (means ᠓D). Mean global CBF increased from normoxic levels of 0.39 ᠰ.13 to 0.45 ᠰ.13 ml/g during hypoxia. Increases in regional CBF were not uniform and ranged from 9.9 ᠸ.6% in the occipital lobe to 28.9 ᠱ0.3% in the nucleus accumbens. Regions of interest that were better perfused during normoxia generally showed a greater regional CBF response. Phylogenetically older regions of the brain tended to show larger ...
https://research-repository.griffith.edu.au/handle/10072/23274
Different cerebral hemodynamic responses between sexes and various vessels in orthostatic stress tests<...
TY - JOUR. T1 - Different cerebral hemodynamic responses between sexes and various vessels in orthostatic stress tests. AU - Wang, Yuh Jen. AU - Chao, A. Ching. AU - Chung, Chih Ping. AU - Huang, Ying Ju. AU - Hu, Han Hwa. PY - 2010/9/1. Y1 - 2010/9/1. N2 - Objective: The argument about why the head-up tilt table test (HUT) does not include the posterior cerebral circulation, which is mainly responsible for syncope, as a monitor target has not been resolved. It is also unclear whether there is a sex difference in cerebral blood flow (CBF) changes. We hypothesized that orthostatic CBF changes more in the posterior circulation than in the anterior circulation and is different between sexes. Methods: Thirty healthy volunteers (13 female and 17 male) were recruited for the HUT. The blood pressure (BP), middle cerebral artery flow velocity (MCAFV), and posterior cerebral artery flow velocity (PCAFV) were monitored simultaneously. Static cerebral autoregulation (CA) was calculated. Results: The female ...
https://tmu.pure.elsevier.com/en/publications/different-cerebral-hemodynamic-responses-between-sexes-and-variou
Regional Differences in β-Adrenergic Effects on Local Cerebral Blood Flow and Adrenergic Innervation | SpringerLinkRegional Differences in β-Adrenergic Effects on Local Cerebral Blood Flow and Adrenergic Innervation | SpringerLink
Although it is now well documented (6, 8) that pial as well as intracerebral vessels are amply supplied with sympathetic adrenergic nerves which, as shown for pial arteries, fulfill ultra-structural...
https://link.springer.com/chapter/10.1007/978-3-642-65814-3_116
Cerebral Blood FlowCerebral Blood Flow
Four major, interdependent mechanisms are involved in the control of cerebral blood flow: metabolic coupling: neural control, involving both extrinsic and intrinsic neural pathways: Pco2 and autoregulation. Although this division may be somewhat artificial and these control mechanisms probably operate in concert, it is useful to consider each separately. Metabolic Control Local cerebral blood flow (CBF) is regionally heterogeneous. The varied pattern of CBF is neither random nor related to the anatomic organization of the cerebral vasculature or to known differences in the innervation patterns of the cerebral vessels. Neuronal activity is the principal energy-consuming process in the brain. Local cerebral blood flow adjusts to the level of energy generation; therefore, it is the activity in the neuronal circuits that is the major determinant of variations and regional patterns of cerebral blood flow. Normally there is exquisite coupling between the regional cerebral metabolic demand for oxygen ...
http://www.vascularneurosurgery.com/cbf.html
Effects of Pentobarbital and Isoflurane on Regional Cerebral Oxygen Extraction and Consumption with Middle Cerebral Artery...Effects of Pentobarbital and Isoflurane on Regional Cerebral Oxygen Extraction and Consumption with Middle Cerebral Artery...
Oak Za Chi, Hwu Meei Wei, Dorene A. OHara, Arabinda K. Sinha, Harvey R. Weiss; Effects of Pentobarbital and Isoflurane on Regional Cerebral Oxygen Extraction and Consumption with Middle Cerebral Artery Occlusion in Rats. Anesthesiology 1993;79(2):299-305. Download citation file:. ...
http://anesthesiology.pubs.asahq.org/article.aspx?articleid=1950315
30: CEREBRAL BLOOD FLOW AND CEREBRAL OXYGEN METABOLISM IN NORMAL AGING: A PRECURSOR FOR STUDY OF DEMENTIA AND ALZHEIMERS...30: CEREBRAL BLOOD FLOW AND CEREBRAL OXYGEN METABOLISM IN NORMAL AGING: A PRECURSOR FOR STUDY OF DEMENTIA AND ALZHEIMERS...
Background and aims: Aging brain has been demonstrated to be the main risk factor for dementia and Alzheimers disease (AD). Recent findings provide clear evidence that the structural and functional integrity of the brain depends on the delicate balance between substrate delivery through blood flow and energy demands imposed by neural activity. Imaging studies of aging have in general shown reductions of cerebral blood flow (CBF) and the cerebral metabolic rates of oxygen (CMRO2) in healthy elderly adults. Based on the existing evidence, we hypothesized the CBF and CMRO2 in healthy young subjects will be higher than CBF and CMRO2 in elderly adults which itself should be higher than AD patients. Therefore, we designed the present studies specifically to reveal the role of defective cerebral oxygen metabolism and cerebral blood flow in normal aging. ...
https://bmjopen.bmj.com/content/7/Suppl_1/bmjopen-2016-015415.30
Nitric oxide synthase inhibition alters cerebral blood flow and oxygen balance in focal cerebral ischemia in rats. | StrokeNitric oxide synthase inhibition alters cerebral blood flow and oxygen balance in focal cerebral ischemia in rats. | Stroke
This study investigated whether the nitric oxide synthase inhibitor NG-nitro-L-arginine-methyl ester (L-NAME) would alter blood flow and oxygen balance in the ischemic cerebrocortex of isoflurane-anesthetized Long-Evans rats.. Fifteen minutes after middle cerebral artery occlusion, L-NAME (1.5 mg/min per kilogram) was infused intravenously to the L-NAME group (n = 14), and normal saline was given to the control group (n = 14) for 45 minutes. In each group, regional cerebral blood flow was determined with [14C]iodoantipyrine, and arterial and venous oxygen saturations were determined by microspectrophotometry.. In both groups regional cerebral blood flow of the ischemic cortex was significantly lower than that of the contralateral cortex ([mean +/- SD] 55 +/- 13 versus 110 +/- 29 mL/min per 100 g in the control group and 35 +/- 13 versus 90 +/- 24 mL/min per 100 g in the L-NAME group). Compared with the blood flow in the ischemic cortex of the control group, L-NAME significantly reduced ischemic ...
http://stroke.ahajournals.org/content/25/2/445
Factors Influencing Cerebral Blood Flow and Metabolism | CirculationFactors Influencing Cerebral Blood Flow and Metabolism | Circulation
The results of studies utilizing the nitrous oxide technic for measuring cerebral blood flow have been reviewed and divided into three groups: (1) those in which cerebral blood flow and metabolism were normal, (2) those in which cerebral blood flow was increased, and (3) those in which cerebral blood flow and metabolism were decreased. The factors which apparently regulate and control cerebral blood flow and metabolism are reviewed and discussed.. ...
http://circ.ahajournals.org/content/5/2/225
Theoretical Basis of Hemodynamic MR Imaging Techniques to Measure Cerebral Blood Volume, Cerebral Blood Flow, and Permeability ...Theoretical Basis of Hemodynamic MR Imaging Techniques to Measure Cerebral Blood Volume, Cerebral Blood Flow, and Permeability ...
3) with the assumption that the large and small vessel Hcts are equal.12. Strictly, recirculation effects should be recognized and removed from the curves. In reality, unless there is significant BBB permeability or areas of very low flow, recirculation effects may be ignored and actually lead to improved estimates of plasma volume that are less sensitive to contrast agent delivery rates (ie, CBF). In low-flow regions, if the tracer does not complete its first passage within the time given for the measurement (usually about 25-30 seconds), it will be undercounted and vp will be underestimated. Because of this result, some authors writing about ischemia have used the term perfused CBV.13 This may account for the discrepancies seen in between PWI and C15O PET estimates of CBV in ischemia.14 In fact, in the extreme, one would prefer to image as late after injection as possible; when the contrast agent concentration is changing slowly, it more closely approximates a steady-state or blood pool ...
http://www.ajnr.org/content/28/10/1850?ijkey=ab25b643ba4bc23f986f234d309e7d93374cdc5c&keytype2=tf_ipsecsha
Contribution of arterial Windkessel in low-frequency cerebral hemodynamics during transient changes in blood pressure - TeesRep...
The Windkessel properties of the vasculature are known to play a significant role in buffering arterial pulsations, but their potential importance in dampening low-frequency fluctuations in cerebral blood flow has not been clearly examined. In this study, we quantitatively assessed the contribution of arterial Windkessel (peripheral compliance and resistance) in the dynamic cerebral blood flow response to relatively large and acute changes in blood pressure. Middle cerebral artery flow velocity (MCA(V); transcranial Doppler) and arterial blood pressure were recorded from 14 healthy subjects. Low-pass-filtered pressure-flow responses (,0.15 Hz) during transient hypertension (intravenous phenylephrine) and hypotension (intravenous sodium nitroprusside) were fitted to a two-element Windkessel model. The Windkessel model was found to provide a superior goodness of fit to the MCA(V) responses during both hypertension and hypotension (R² = 0.89 ± 0.03 and 0.85 ± 0.05, respectively), with a ...
https://tees.openrepository.com/tees/handle/10149/218255
Measurement of oxygen extraction fraction (OEF): An optimized BOLD signal model for use with hypercapnic and hyperoxic...Measurement of oxygen extraction fraction (OEF): An optimized BOLD signal model for use with hypercapnic and hyperoxic...
Several techniques have been proposed to estimate relative changes in cerebral metabolic rate of oxygen consumption (CMRO2) by exploiting combined BOLD fMRI and cerebral blood flow data in conjunction with hypercapnic or hyperoxic respiratory challenges. More recently, methods based on respiratory challenges that include both hypercapnia and hyperoxia have been developed to assess absolute CMRO2, an important parameter for understanding brain energetics. In this paper, we empirically optimize a previously presented original calibration model relating BOLD and blood flow signals specifically for the estimation of oxygen extraction fraction (OEF) and absolute CMRO2.To do so, we have created a set of synthetic BOLD signals using a detailed BOLD signal model to reproduce experiments incorporating hypercapnic and hyperoxic respiratory challenges at 3 T. A wide range of physiological conditions was simulated by varying input parameter values (baseline cerebral blood volume (CBV0), baseline cerebral ...
https://ricerca.unich.it/handle/11564/722311
Aging and recognition memory: changes in regional cerebral blood flow associated with components of reaction time distributions...Aging and recognition memory: changes in regional cerebral blood flow associated with components of reaction time distributions...
We used H(2)15O positron emission tomography (PET) to measure age-related changes in regional cerebral blood flow (rCBF) during a verbal recognition memory task. Twelve young adults (20 to 29 years) and 12 older adults (62 to 79 years) participated. Separate PET scans were conducted during Encoding, Baseline, and Retrieval conditions. Each of the conditions involved viewing a series of 64 words and making a two-choice response manually. The complete reaction time (RT) distributions in each task condition were characterized in terms of an ex-Gaussian model (convolution of exponential and Gaussian functions). Parameter estimates were obtained for the mean of the exponential component (tau), representing a task-specific decision process and the mean of the Gaussian component (mu) representing residual sensory coding and response processes. Independently of age group, both tau and mu were higher in the Encoding and Retrieval conditions than in the Baseline condition, and tau was higher during ...
https://passport.as.uky.edu/aging-and-recognition-memory-changes-regional-cerebral-blood-flow-associated-components-reaction
Anesthetic Gases: Organ System Effects | Anesthesiology Core Review: Part One Basic Exam | AccessAnesthesiology | McGraw-Hill...Anesthetic Gases: Organ System Effects | Anesthesiology Core Review: Part One Basic Exam | AccessAnesthesiology | McGraw-Hill...
All inhaled anesthetics increase cerebral blood flow and decrease cerebral metabolic rate for oxygen (CMRO2). Nitrous oxide, however, will increase CMRO2. Nitrous oxide, as well as inhaled anesthetics, causes cerebral vasodilation. However, if the patients blood pressure drops, the increase in cerebral blood flow will be attenuated or abolished because volatile anesthetics inhibit autoregulation. Isoflurane causes the least cerebral vasodilation, maintaining autoregulation better than other volatile anesthetics. Isoflurane also has no effect on cerebrospinal fluid (CSF) production and decreases resistance to CSF absorption. Desflurane increases CSF production without significantly effecting CSF reabsorption. ...
http://accessanesthesiology.mhmedical.com/content.aspx?sectionid=61587757&bookid=974&jumpsectionID=61587757
Focal cerebral blood flow change during craving for alcohol measured by SPECT. - Semantic ScholarFocal cerebral blood flow change during craving for alcohol measured by SPECT. - Semantic Scholar
To test the hypothesis that craving for alcohol in the alcohol-dependent individual is mediated by a limbic circuit involving the caudate nuclei, regional cerebral blood flow was measured with [99mTc]HMPAO SPECT during control and craving conditions in 9 alcohol-dependent subjects. In all subjects, blood flow in the head of the right caudate nucleus increased during the craving condition, and these blood flow increases were strongly correlated with the experimentally induced increases in craving for alcohol. These new findings suggest a functional role for the limbic striatum in the mediation of craving and impaired control over alcohol consumption.
https://www.semanticscholar.org/paper/Focal-cerebral-blood-flow-change-during-craving-fo-Modell-Mountz/d7db6ffc5807341af3502ebd56ff9a439c51b936
Quantification of cerebral blood flow, cerebral blood volume, and blood-brain-barrier leakage with DCE-MRIQuantification of cerebral blood flow, cerebral blood volume, and blood-brain-barrier leakage with DCE-MRI
Dynamic susceptibility contrast MRI (DSC-MRI) is the current standard for the measurement of Cerebral Blood Flow (CBF) and Cerebral Blood Volume (CBV), but it is not suitable for the measurement of Extraction Flow (EF) and may not allow for absolute quantification. The objective of this study was to …
https://pubmed.ncbi.nlm.nih.gov/19449435/?dopt=Abstract
Small vessel disease is associated with altered cerebrovascular pulsatility but not resting cerebral blood flow. - PubMed -...Small vessel disease is associated with altered cerebrovascular pulsatility but not resting cerebral blood flow. - PubMed -...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
https://www.ncbi.nlm.nih.gov/pubmed/30295558
Effects of exercise therapy on metabolic risk factors, brain atrophy and cerebral blood flow following stroke: A randomised...Effects of exercise therapy on metabolic risk factors, brain atrophy and cerebral blood flow following stroke: A randomised...
Author(s): Moore S, Hallsworth K, Jakovljevic D, Blamire A, He J, Ford G, Rochester L, Trenell M. Publication type: Conference Proceedings (inc. Abstract). Publication status: Published. Conference Name: UK Stroke Forum 2014. Year of Conference: 2014. Pages: 32-32. Print publication date: 01/11/2014. Online publication date: 01/12/2014. ISSN: 1747-4930. Publisher: Wiley-Blackwell Publishing Asia. URL: http://dx.doi.org/10.1111/ijs.12374_12. DOI: 10.1111/ijs.12374_12. Notes: 072. Series Title: International Journal of Stroke. ...
https://eprints.ncl.ac.uk/209431
Serval - Regional cerebral blood flow in depression measured by positron emission tomography: the relationship with clinical...Serval - Regional cerebral blood flow in depression measured by positron emission tomography: the relationship with clinical...
We have previously reported focal abnormalities of regional cerebral blood flow (rCBF) in a group of 33 patients with major depression. This report, on an extended sample of 40 patients who demonstrated identical regional deficits to those previously described, examines the relationships between depressive symptoms and patterns of rCBF. Patients symptom ratings were subjected to factor analysis, producing a three-factor solution. The scores for these three factors, which corresponded to recognizable dimensions of depressive illness, were then correlated with rCBF. The first factor had high loadings for anxiety and correlated positively with rCBF in the posterior cingulate cortex and inferior parietal lobule bilaterally. The second factor had high loadings for psychomotor retardation and depressed mood and correlated negatively with rCBF in the left dorsolateral prefrontal cortex and left angular gyrus. The third factor had a high loading for cognitive performance and correlated positi
https://serval.unil.ch/en/notice/serval:BIB_BA54D58C102B
A Study to Assess Regional Cerebral Blood Flow as an Alzheimer's Disease Biomarker Compared to Positron Emission...A Study to Assess Regional Cerebral Blood Flow as an Alzheimer's Disease Biomarker Compared to Positron Emission...
The aim of the study is to determine if regional cerebral blood flow, measured by dynamic arterial spin labeling (dASL), can be a biomarker for stage of Alzheimers disease. The study is designed to be conducted in 2 parts in participants with mild to moderate Alzheimers disease, and participants with normal cognition. Various imaging studies will be done using magnetic resonance imaging (MRI) and positron emission tomography (PET) along with neurocognitive assessments. Participants who meet the study-entry criteria will have up to 8 study visits. Repeat imaging studies may be required if the initial data are incomplete or un-interpretable. The maximum number of PET scans during the study will be limited to four ...
https://clinicaltrials.gov/ct2/show/NCT00757939?term=%22Alzheimer+Disease%22+%5BDISEASE%5D&rank=13
A Study to Assess Regional Cerebral Blood Flow as an Alzheimer's Disease Biomarker Compared to Positron Emission...A Study to Assess Regional Cerebral Blood Flow as an Alzheimer's Disease Biomarker Compared to Positron Emission...
The aim of the study is to determine if regional cerebral blood flow, measured by dynamic arterial spin labeling (dASL), can be a biomarker for stage of Alzheimers disease. The study is designed to be conducted in 2 parts in participants with mild to moderate Alzheimers disease, and participants with normal cognition. Various imaging studies will be done using magnetic resonance imaging (MRI) and positron emission tomography (PET) along with neurocognitive assessments. Participants who meet the study-entry criteria will have up to 8 study visits. Repeat imaging studies may be required if the initial data are incomplete or un-interpretable. The maximum number of PET scans during the study will be limited to four ...
https://clinicaltrials.gov/ct2/show/NCT00757939?cond=%22Alzheimer+Disease%22&rank=15
Cholinergic stimulation alters performance and task-specific regional cerebral blood flow during working memory - IMT...Cholinergic stimulation alters performance and task-specific regional cerebral blood flow during working memory - IMT...
Modulation of the cholinergic neurotransmitter system results in changes in memory performance, including working memory (WM), in animals and in patients with Alzheimer disease. To identify associated changes in the functional brain response, we studied performance measures and regional cerebral blood flow (rCBF) using positron emission tomography (PET) in healthy subjects during performance of a WM task. Eight control subjects received an infusion of saline throughout the study and 13 experimental subjects received a saline infusion for the first 2 scans followed by a continuous infusion of physostigmine, an acetylcholinesterase inhibitor, for the subsequent 8 scans. rCBF was measured using H215O and PET in a sequence of 10 PET scans that alternated between rest and task scans. During task scans, subjects performed the WM task for faces. Physostigmine both improved WM efficiency, as indicated by faster reaction times, and reduced WM task-related activity in anterior and posterior regions of ...
http://eprints.imtlucca.it/3417/
Pooling data from different populations: should there be regional differences in cerebral haemodynamics? | BMC Neurology | Full...Pooling data from different populations: should there be regional differences in cerebral haemodynamics? | BMC Neurology | Full...
Though genetic and environmental determinants of systemic haemodynamic have been reported, surprisingly little is known about their influences on cerebral haemodynamics. We assessed the potential geographical effect on cerebral haemodynamics by comparing the individual differences in cerebral blood flow velocity (CBFv), vasomotor tone (critical closing pressure- CrCP), vascular bed resistance (resistance-area product- RAP) and cerebral autoregulation (CA) mechanism on healthy subjects and acute ischaemic stroke (AIS) patients from two countries. Participants were pooled from databases in Leicester, United Kingdom (LEI) and São Paulo, Brazil (SP) research centres. Stroke patients admitted within 48 h of ischaemic stroke onset, as well as age- and sex-matched controls were enrolled. Beat-to-beat blood pressure (BP) and bilateral mean CBFv were recorded during 5 min baseline. CrCP and RAP were calculated. CA was quantified using transfer function analysis (TFA) of spontaneous oscillations in arterial BP
https://bmcneurol.biomedcentral.com/articles/10.1186/s12883-018-1155-8/tables/3
Pooling data from different populations: should there be regional differences in cerebral haemodynamics? | BMC Neurology | Full...Pooling data from different populations: should there be regional differences in cerebral haemodynamics? | BMC Neurology | Full...
Though genetic and environmental determinants of systemic haemodynamic have been reported, surprisingly little is known about their influences on cerebral haemodynamics. We assessed the potential geographical effect on cerebral haemodynamics by comparing the individual differences in cerebral blood flow velocity (CBFv), vasomotor tone (critical closing pressure- CrCP), vascular bed resistance (resistance-area product- RAP) and cerebral autoregulation (CA) mechanism on healthy subjects and acute ischaemic stroke (AIS) patients from two countries. Participants were pooled from databases in Leicester, United Kingdom (LEI) and São Paulo, Brazil (SP) research centres. Stroke patients admitted within 48 h of ischaemic stroke onset, as well as age- and sex-matched controls were enrolled. Beat-to-beat blood pressure (BP) and bilateral mean CBFv were recorded during 5 min baseline. CrCP and RAP were calculated. CA was quantified using transfer function analysis (TFA) of spontaneous oscillations in arterial BP
https://bmcneurol.biomedcentral.com/articles/10.1186/s12883-018-1155-8/tables/5
Fibromyalgia (FM) in women. Abnormalities of regional cerebral blood flow in the thalamus & the caudate nucleus are associated...Fibromyalgia (FM) in women. Abnormalities of regional cerebral blood flow in the thalamus & the caudate nucleus are associated...
The goal of this study was to determine if regional cerebral blood flow (rCBF)in the left and right hemithalami or the left and right heads of the cau
http://www.prohealth.com/library/showarticle.cfm?libid=6862
Opioids and the prostanoid system in the control of cerebral blood flow in hypotensive piglets<...
TY - JOUR. T1 - Opioids and the prostanoid system in the control of cerebral blood flow in hypotensive piglets. AU - Armstead, W. M.. AU - Mirro, R.. AU - Busija, D. W.. AU - Leffler, Charles. PY - 1991/1/1. Y1 - 1991/1/1. N2 - The interaction between opioid and prostanoid mechanisms in the control of cerebral hemodynamics was investigated in the conscious hypotensive piglet. Radiomicrospheres were used to determine regional cerebral blood flow (rCBF) in piglets pretreated with the opioid receptor antagonist, naloxone, or its vehicle, saline, during normotension, hypotension, and after the administration of indomethacin, a cyclooxygenase inhibitor, during hypotension. Hemorrhage (30 ml/kg) decreased systemic arterial pressure from 68 ± 12 to 40 ± 10 mm Hg but did not decrease blood flow to any brain region. Indomethacin treatment (5 mg/kg) of hypotensive piglets decreased blood flow to all brain regions within 20 min; this decrease blood flow to all brain regions within 20 rebral vascular ...
https://uthsc.pure.elsevier.com/en/publications/opioids-and-the-prostanoid-system-in-the-control-of-cerebral-bloo
Impaired sympathetic regulation of cerebral blood flow in patients with cirrhosis of the liver | Clinical Science | Portland...Impaired sympathetic regulation of cerebral blood flow in patients with cirrhosis of the liver | Clinical Science | Portland...
Continuous recording of mean cerebral blood flow velocity (MCBFV) by Doppler ultrasound allows detection of low-frequency (LF) oscillations, which reflect sympathetic activity in the cerebral circulation. To establish whether the sympathetic drive to the cerebral circulation is altered in patients with compensated cirrhosis, and, if so, where alterations take place, LF oscillations of MCBFV, heart rate (RR interval) and systolic arterial pressure (SAP) were analysed in 10 patients with cirrhosis and 10 control subjects during supine rest and on stimulation of carotid baroreceptors using a neck chamber applying sinusoidal suction. Bivariate analysis was used to study the relationship between pairs of oscillations. In the case of a significant association, the delay in the appearance of the oscillation in MCBFV, SAP and RR was calculated. Baroreceptor stimulation induced significant increases in SAP LF and RR LF power in both groups, while MCBFV LF power increased only in controls. During ...
https://portlandpress.com/clinsci/article-abstract/103/1/43/67361/Impaired-sympathetic-regulation-of-cerebral-blood?redirectedFrom=fulltext
White matter lesions after occlusion of the bilateral carotid arteries in the rat -temporal profile of cerebral blood flow (CBF...White matter lesions after occlusion of the bilateral carotid arteries in the rat -temporal profile of cerebral blood flow (CBF...
TY - JOUR. T1 - White matter lesions after occlusion of the bilateral carotid arteries in the rat -temporal profile of cerebral blood flow (CBF), oligodendroglia and myelin. AU - Tomimoto, Hidekazu. AU - Akiguchi, Ichiro. AU - Wakita, Hideaki. AU - Kimura, Jun. PY - 1997/12/1. Y1 - 1997/12/1. N2 - In the present investigation, we examined cerebral blood flow (CBF), numerical density of oligodendroRlia and extent of white matter lesions after bilateral libation of common carotid arteries in Wistar rats, Doppler flow meter re\ealed a reduction of CBF to 30-40, of that before operation after 1 and 3 days, however recovered to ,10 60 ‰, after 7 and 14 days, Semiquantitative evaluation with immuohistochemistry for transferrin showed a numerical decrease of oligodendroglia in the medial corpus callosum after 14 and !i() clays, Tissue rarefaction promptly occurred in the optic nerve and optic tract after ,, days, whereas it was- delayed to 7 clays after operation and increased in intensity ...
https://pure.fujita-hu.ac.jp/ja/publications/white-matter-lesions-after-occlusion-of-the-bilateral-carotid-art
What is Cerebral Perfusion Pressure? | EP Wellness & Functional Medicine ClinicWhat is Cerebral Perfusion Pressure? | EP Wellness & Functional Medicine Clinic
In the article, cerebral perfusion pressure, or CPP, is the net pressure gradient which affects cerebral blood flow to the brain, known as brain perfusion.
https://wellnessdoctorrx.com/what-is-cerebral-perfusion-pressure/
Cerebrovascular Disease Pathophysiology - Clinical FeaturesCerebrovascular Disease Pathophysiology - Clinical Features
Standard techniques of cerebral blood flow (CBF) measurement provide information on both global and regional flow in patients with cerebral ischaemia or infarction. Recent availability of positron emission tomography (PET), recording oxygen and glucose metabolism, as well as blood flow and blood volume, gives a more detailed and accurate understanding of pathophysiological changes after stroke.. Changes in cerebral infarction. NON-ISCHAEMIC HEMISPHERE. Mild reduction in global CBF - perhaps due to transneuronal depression of metabolism in the unaffected hemisphere - diaschisis.. In the normal brain, cerebral blood flow to a particular part varies depending on the metabolic requirements, i.e. the supply of 02 and glucose is coupled to the tissue needs. After infarction, between areas of reduced flow and areas of luxury perfusion, lie areas of relative luxury perfusion where reduced flow exceeds the tissue requirements, i.e. uncoupling of flow and metabolism has occurred.. Studies with SPECT ...
https://www.alpfmedical.info/clinical-features/cerebrovascular-disease-pathophysiology.html
Optical Monitoring of Cerebral Blood Flow at Bedside for Individualized Stroke CareOptical Monitoring of Cerebral Blood Flow at Bedside for Individualized Stroke Care
The effects of positioning of head of bed positioning on blood flow reaching the brain can now be monitored non-invasively and continuously using a new device designed by University of Pennsylvania.
http://www.medindia.net/news/optical-monitoring-of-cerebral-blood-flow-at-bedside-for-individualized-stroke-care-133544-1.htm
Effects of Adenylate Cyclase, Guanylate Cyclase and KATP Channel Blockade on the Cerebral Blood Flow Response Induced by...Effects of Adenylate Cyclase, Guanylate Cyclase and KATP Channel Blockade on the Cerebral Blood Flow Response Induced by...
This study was performed to investigate the regulatory mechanism of cerebral blood flow of adenosine A $_{2B}$ receptor agonist in the rats, and to define whether its mechanism is mediated by adenylate cyclase, guanylate cyclase and potassium channel. In pentobarbital-anesthetized, pancuronium-par...
http://www.ndsl.kr/ndsl/search/detail/article/articleSearchResultDetail.do?cn=JAKO200504704039035
Aerobic fitness, physical activity, and brain function in healthy young adultsAerobic fitness, physical activity, and brain function in healthy young adults
Mounting evidence indicates that regular engagement in aerobic exercise improves executive functioning and cerebrovascular health in older adulthood. Recent evidence also points toward some similar benefits in young adults, despite presumed optimal brain health in that population. The present study sought to clarify which specific cognitive functions are linked to regular exercise in young adults (18-30 years), and to gain insight into the possible mechanisms underlying such links. To this end, the current study examined performance on a wide variety of executive function tasks in relation to aerobic fitness, self-reported habitual physical activity, and cerebrovascular health (as measured by resting cerebral blood flow, which was indexed by blood flow velocity through the middle cerebral artery; and cerebrovascular reactivity to carbon dioxide - the most potent regulatory stimulus of the cerebrovasculature). Multiple regression analyses revealed that more frequent physical activity, but not ...
https://ourarchive.otago.ac.nz/handle/10523/2178
Research at The Department of Anaesthesiology Abdominal CentreResearch at The Department of Anaesthesiology Abdominal Centre
Cerebral blood flow and metabolism have been evaluated during exercise to elicit robust activation compared with during anaesthesia. It is demonstrated that physical exercise requires an approximately 20 % increase in cerebral blood flow and metabolic rate for oxygen. This reflects that low intensity exercise is associated with increasing cerebral oxygenation, while cerebral oxygenation decreases during maximal exercise, since marked hyperventilation reduces arterial carbon dioxide tension and therefore cerebral blood flow at the same time as the metabolic rate for oxygen is elevated ...
https://www.rigshospitalet.dk/english/departments/abdominal-centre/department-of-anaesthesiology/research/Pages/research.aspx
Plus itPlus it
Type 2 diabetes exerts complex effects on cerebral microvasculature that may alter cerebral blood flow regulation. We found a decrease of mean BFV and an increase of CVR in type 2 diabetic patients during baseline, hypocapnia, and hypercapnia. Baseline mean BFV was negatively associated with periventricular WMH grade and volume on T2-weighted images and with A1C and inflammation markers. WMHs were also linked with uncontrolled diabetes, elevated CVR, and impaired CO2 reactivity. The relationship between WMH, uncontrolled diabetes and reduced BFV is of clinical relevance as a potential mechanism for cerebrovascular disease in elderly with type 2 diabetes.. Aging is associated with brain atrophy, changes in frontal subcortical white matter, and executive cognitive dysfunction (9). The CO2 reactivity diminishes with age, uncontrolled diabetes, and risk factors for atherosclerosis (22). In community-living elderly people, blood flow in the WMHs was lower compared with normal-appearing white matter ...
http://care.diabetesjournals.org/content/29/7/1529
Long-term effects of tacrine on regional cerebral blood flow changes in Alzheimers diseaseLong-term effects of tacrine on regional cerebral blood flow changes in Alzheimers disease
article{a42a0f99-94fd-4913-b3c1-936a0a2ea31b, abstract = {Regional cerebral blood flow (rCBF) was studied in patients with Alzheimers disease (AD) before and after 14 months of tacrine treatment. The treated group was compared with an identical reference group of untreated AD patients. At baseline the two groups showed an identical rCBF and mean hemispheric blood flow. After 14 months the tacrine-treated patients showed a stable rCBF level and a significant increase in rCBF in the central-parietal regions, compared to the untreated reference group, who showed typical AD reductions in rCBF in these regions. Clinical outcome: 7 of 9 patients in the tacrine group were clinically unchanged or slightly improved during the study time. In the untreated group 8 of 11 patients had deteriorated in clinical assessments and none had improved. Long-term tacrine treatment in Alzheimers disease may delay the progression of symptoms.}, author = {Minthon, Lennart and Nilsson, Karin and Edvinsson, Lars and ...
https://lup.lub.lu.se/search/publication/a42a0f99-94fd-4913-b3c1-936a0a2ea31b
Phenylephrine increases cerebral blood flow during low-flow hypothermic cardiopulmonary bypass in baboons<...Phenylephrine increases cerebral blood flow during low-flow hypothermic cardiopulmonary bypass in baboons<...
TY - JOUR. T1 - Phenylephrine increases cerebral blood flow during low-flow hypothermic cardiopulmonary bypass in baboons. AU - Schwariz, Arthur E.. AU - Minanov, Oktavijan. AU - Stone, J. Gilbert. AU - Adams, David C.. AU - Sandhu, Aqeel A.. AU - Pearson, Mark E.. AU - Kwiatkowski, Pawel. AU - Young, William L.. AU - Michler, Robert E.. PY - 1996/8/23. Y1 - 1996/8/23. N2 - Background: Although low-flow cardiopulmonary bypass (CPB) has become a preferred technique for the surgical repair of complex cardiac lesions in children, the relative hypotension and decrease in cerebral blood flow (CBF) associated with low flow may contribute to the occurrence of postoperative neurologic injury. Therefore, it was determined whether phenylephrine administered to increase arterial blood pressure during low-flow CPB increases CBF. Methods: Cardiopulmonary bypass was initiated in seven baboons during fentanyl, midazolam, and isoflurane anesthesia. Animals were cooled at a pump flow rate of 2.5 1 · min -1 · m ...
https://einstein.pure.elsevier.com/en/publications/phenylephrine-increases-cerebral-blood-flow-during-low-flow-hypot-2
Cognitive function and dynamic cerebral blood flow regulation in multiple concussions<...
TY - JOUR. T1 - Cognitive function and dynamic cerebral blood flow regulation in multiple concussions. AU - Kumazaki, Akira. AU - Ogoh, Shigehiko. AU - Hirasawa, Ai. AU - Sakai, Sadayoshi. AU - Hirose, Norikazu. PY - 2018/3. Y1 - 2018/3. N2 - Background: Concussion causes acute, short-term brain dysfunctions. However, the impact of repetitive concussion history on brain function remains unclear. Objectives: The present study examined the effect of a history of multiple concussions on the cognitive functions and dynamic cerebral blood flow (CBF) regulation in collegiate rugby football players. Methods: Nine male rugby football players with a history of≤1 concussion and nine players with a history of multiple concussions (≤ 4 concussions) participated in this study. Reaction time and working memory were assessed using a neurocognitive assessment device (CogSport; CogState Ltd., Melbourne, Australia). Arterial blood pressure and middle cerebral artery blood velocity (MCAv) were measured ...
https://waseda.pure.elsevier.com/en/publications/cognitive-function-and-dynamic-cerebral-blood-flow-regulation-in-
Effect of stimulation of carotid chemoreceptors on total and regional cerebral blood flow. | Circulation ResearchEffect of stimulation of carotid chemoreceptors on total and regional cerebral blood flow. | Circulation Research
This study was performed to determine whether stimulation of the carotid chemoreceptors increases total or regional cerebral blood flow and whether activation of arterial chemoreceptors contributes to cerebral vasodilation during systemic hypoxemia. In anesthetized and ventilated dogs, carotid chemoreceptors were stimulated with nicotine or hypoxic and hypercapnic blood. To measure total and regional cerebral blood flow, we used labeled 15-mu microspheres. Stimulation of chemoreceptors did not increase cerebral blood flow or produce significant redistribution of cerebral blood flow, even though the chemoreflex was intact in these animals (as manifested by vasoconstriction in muscle, kidney, and small bowel) and the cerebral vessels dilated in response to systemic hypercapnia. In other studies in anesthetized, ventilated dogs and rhesus monkeys, cerebral vasodilator responses to systemic hypoxemia were observed before and after denervation of carotid and aortic chemoreceptors. Systemic hypoxemia ...
http://circres.ahajournals.org/content/38/1/20
Effect of central cholinergic stimulation on regional cerebral blood flow in Alzheimer disease. - Oxford Neuroscience
Patients with Alzheimer disease (AD) had reduced regional cerebral blood flow (rCBF) in the posterior parietotemporal region compared with controls, as determined with technetium-99m hexamethyl propyleneamine oxime and single photon emission tomography. Central cholinergic stimulation with physostigmine produced a focal increase in rCBF in the posterior parietotemporal region in the patients with AD but not in controls.
https://www.neuroscience.ox.ac.uk/publications/185820
Low Cerebral Oxygen Consumption and Blood Flow in Patients With Cirrhosis and an Acute Episode of Hepatic Encephalopathy<...
TY - JOUR. T1 - Low Cerebral Oxygen Consumption and Blood Flow in Patients With Cirrhosis and an Acute Episode of Hepatic Encephalopathy. AU - Iversen, Peter. AU - Sørensen, Michael. AU - Bak, Lasse Kristoffer. AU - Waagepetersen, Helle Sønderby. AU - Vafaee, Manouchehr Seyedi. AU - Borghammer, Per. AU - Mouridsen, Kim. AU - Jensen, Svend Borup. AU - Vilstrup, Hendrik. AU - Schousboe, Arne. AU - Ott, Peter. AU - Gjedde, Albert. AU - Keiding, Susanne. PY - 2009/3. Y1 - 2009/3. N2 - Background & Aims: It is unclear whether patients with hepatic encephalopathy (HE) have disturbed brain oxygen metabolism and blood flow. Methods: We measured cerebral oxygen metabolism rate (CMRO2) by using 15O-oxygen positron emission tomography (PET); and cerebral blood flow (CBF) by using 15O-water PET in 6 patients with liver cirrhosis and an acute episode of overt HE, 6 cirrhotic patients without HE, and 7 healthy subjects. Results: Neither whole-brain CMRO2 nor CBF differed significantly between cirrhotic ...
https://jhu.pure.elsevier.com/en/publications/low-cerebral-oxygen-consumption-and-blood-flow-in-patients-with-c-3
Quantitative Cerebral Blood Flow Measurement with Dynamic Perfusion CT Using the Vascular-Pixel Elimination Method: Comparison...Quantitative Cerebral Blood Flow Measurement with Dynamic Perfusion CT Using the Vascular-Pixel Elimination Method: Comparison...
BACKGROUND AND PURPOSE: Blood vessels are usually conspicuous on dynamic CT perfusion images. The presence of large vessels may lead to overestimation of the quantitative value of cerebral blood flow (CBF). We evaluated the efficacy of the vascular-pixel elimination (VPE) method in quantitative CT perfusion imaging, in comparison with positron emission tomography (PET).. METHODS: Five healthy volunteers underwent CT perfusion and PET studies. A four-channel multi-detector row CT scanner was used. Dynamic cine scanning was performed after bolus injection of an intravenous contrast agent. CT-CBF was calculated by the central volume principle and deconvolution method. PET was performed after infusion of 15O-labeled water. PET-CBF was calculated by using a nonlinear least squares method. Average CBF values of the whole section, gray matter, and white matter with both CT and PET were compared after image registration. The comparison was performed with and without VPE. In the VPE method, the vascular ...
http://www.ajnr.org/content/24/3/419.abstract
Regional cerebral blood flow during mechanical hyperventilation in patients with fulminant hepatic failure
Hyperventilation is frequently used to prevent or postpone the development of cerebral edema and intracranial hypertension in patients with fulminant hepatic failure (FHF). The influence of such therapy on regional cerebral blood flow (rCBF) remains, however, unknown. In this study the CBF-distribution pattern was determined within the first 12 hours after development of hepatic encephalopathy (HE) stage 4 before and during hyperventilation. Ten consecutive patients (median age 48 [range 33-57] years) with FHF and 9 healthy controls (median age 54 [24-58] years) had rCBF determined by single photon emission computed tomography (SPECT) using intravenous injection of 133Xenon. For determination of high resolution CBF pattern, the patients were also studied with 99mTc-hexa-methylpropyleneamine oxime (HMPAO) in the hyperventilation condition. There was no significant difference in the rCBF distribution pattern during normoventilation as compared with hyperventilation. The anterior to posterior (AP) ...
https://curis.ku.dk/portal/da/publications/regional-cerebral-blood-flow-during-mechanical-hyperventilation-in-patients-with-fulminant-hepatic-failure
Distribution of regional cerebral blood flow in voluntarily diving rats. | Journal of Experimental BiologyDistribution of regional cerebral blood flow in voluntarily diving rats. | Journal of Experimental Biology
The distribution of regional cerebral blood flow (rCBF) was examined in conscious, voluntarily diving rats using the brain blood flow tracer N-[14C]isopropyl-p-iodoamphetamine and quantitative autoradiography. A detailed examination of the regional distribution of cerebral blood flow revealed that almost all brain regions were hyperperfused during diving. During diving, rCBF increased by an average of 1.7-fold in 29 of the 33 brain regions examined, despite a 69.2 % decrease in cardiac output. Only some regions of the basal ganglia (caudate-putamen and globus pallidus) and limbic areas (hippocampus and amygdala) did not increase rCBF significantly during diving. We determined that the increase in rCBF during diving is primarily due to a corresponding 20.9 % decrease in cerebrovascular resistance. A significant increase in perfusion pressure during diving also potentially contributed to the increase in rCBF. Because some brain regions did not increase flow significantly during diving, these ...
https://jeb.biologists.org/content/201/4/549
Raised intracranial pressure and the cerebral circulation - Enlighten: ThesesRaised intracranial pressure and the cerebral circulation - Enlighten: Theses
The first five chapters of the thesis review the literature on intracranial pressure, the cerebral circulation and their interrelation and set the scene for the experimental work which is described in chapters 6 to 11. Intracranial pressure is now measured routinely in many clinical centres but a great deal of caution is required in interpreting the results, particularly with respect to the method of measurement, the history of any raised pressure and the values of other physiological variables such as blood pressure and cerebral blood flow. The cerebral circulation itself displays a remarkable tendency to remain constant, the fundamental concept being that there exists a basic control mechanism which acts to maintain cerebral blood flow in order to meet the metabolic requirements of the brain. The methods used to measure cerebral blood flow in the work described are metabolically inert gas clearance techniques based on the Pick principle. Hemisphere blood flow in baboons was measured by the ...
http://theses.gla.ac.uk/72085/
Cerebral dysfunction in fibromyalgia (FM): evidence from regional cerebral blood flow measurements, otoneurological tests &...Cerebral dysfunction in fibromyalgia (FM): evidence from regional cerebral blood flow measurements, otoneurological tests &...
Measurements of regional cerebral blood flow (rCBF), analysis ofcerebrospinal fluid, auditory brain stem responses (ABR) andoculomotor tests
http://www.prohealth.com/library/showarticle.cfm?libid=6820
Quantification of Serial Cerebral Blood Flow in Acute Stroke Using Arterial Spin Labeling. - Nuffield Department of Clinical...
BACKGROUND AND PURPOSE: Perfusion-weighted imaging is used to select patients with acute ischemic stroke for intervention, but knowledge of cerebral perfusion can also inform the understanding of ischemic injury. Arterial spin labeling allows repeated measurement of absolute cerebral blood flow (CBF) without the need for exogenous contrast. The aim of this study was to explore the relationship between dynamic CBF and tissue outcome in the month after stroke onset. METHODS: Patients with nonlacunar ischemic stroke underwent ≤5 repeated magnetic resonance imaging scans at presentation, 2 hours, 1 day, 1 week, and 1 month. Imaging included vessel-encoded pseudocontinuous arterial spin labeling using multiple postlabeling delays to quantify CBF in gray matter regions of interest. Receiver-operator characteristic curves were used to predict tissue outcome using CBF. Repeatability was assessed in 6 healthy volunteers and compared with contralateral regions of patients. Diffusion-weighted and T2-weighted
https://www.ndcn.ox.ac.uk/publications/661871
Different effects of prenatal MAM vs. perinatal THC exposure on regional cerebral blood perfusion detected by Arterial Spin...Different effects of prenatal MAM vs. perinatal THC exposure on regional cerebral blood perfusion detected by Arterial Spin...
Clinical studies consistently report structural impairments (i.e.: ventricular enlargement, decreased volume of anterior cingulate cortex or hippocampus) and functional abnormalities including changes in regional cerebral blood flow in individuals suffering from schizophrenia, which can be evaluated by magnetic resonance imaging (MRI) techniques. The aim of this study was to assess cerebral blood perfusion in several schizophrenia-related brain regions using Arterial Spin Labelling MRI (ASL MRI, 9.4 T Bruker BioSpec 94/30USR scanner) in rats. In this study, prenatal exposure to methylazoxymethanol acetate (MAM, 22 mg/kg) at gestational day (GD) 17 and the perinatal treatment with Delta-9-tetrahydrocannabinol (THC, 5 mg/kg) from GD15 to postnatal day 9 elicited behavioral deficits consistent with schizophrenia-like phenotype, which is in agreement with the neurodevelopmental hypothesis of schizophrenia. In MAM exposed rats a significant enlargement of lateral ventricles and perfusion changes ...
https://www.muni.cz/en/research/publications/1535701
Neonatal cerebral blood flow velocity responses to changes in posture. | Archives of Disease in ChildhoodNeonatal cerebral blood flow velocity responses to changes in posture. | Archives of Disease in Childhood
Maintaining a constant cerebral blood flow during a change in cerebral perfusion pressure is known as autoregulation. The integrity of this phenomenon is considered to be important in preventing cerebral lesions in preterm infants. A study was carried out using Doppler ultrasound measurements of cerebral blood flow velocities (CBFV) as an indicator of alterations in cerebral haemodynamics. CBFV were recorded on a beat to beat basis over 60 second epochs, during which time the cerebral perfusion pressure was changed by rapidly altering the infants posture from horizontal to either 20 degrees head up or head down. An informative response in CBFV was considered to be either (a) a uniphasic, immediate, passive alteration in velocity occurring with the change in posture and without a subsequent change or (b) a biphasic response of an initial change in CBFV followed within 20 seconds by a second response. This latter response is considered to be consistent with autoregulatory activity. A total of 501 ...
http://adc.bmj.com/content/69/3_Spec_No/304
Effect of amphetamine on cerebral blood flow and capillary perfusion<...Effect of amphetamine on cerebral blood flow and capillary perfusion<...
TY - JOUR. T1 - Effect of amphetamine on cerebral blood flow and capillary perfusion. AU - Russo, Karen E.. AU - Hall, Wyatt. AU - Chi, Oak Z.. AU - Sinha, Arabinda K.. AU - Weiss, Harvey R.. PY - 1991/2/22. Y1 - 1991/2/22. N2 - The purpose of this study was to determine the cerebral regional microvascular and vascular responses to amphetamine sulfate at a dose (5 mg/kg) known to affect neuronal function. Cerebral blood flow (14C-iodoantipyrine method) and percent of perfused capillaries (fluorescein isothiocyanate-dextran and alkaline phosphatase staining method) were determined during control and after intravenous administration of amphetamine in conscious Long-Evans rats. Amphetamine caused an increase in blood pressure (34%) and heart rate (31%). There was a significant increase in averaged cerebral blood flow from 98 ±8to 166±9 ml/min/100 g after amphetamine. This flow increase was significant in the cortex, basal ganglia, pons and medulla, however the increase was not significant in the ...
https://www.researchwithrutgers.com/en/publications/effect-of-amphetamine-on-cerebral-blood-flow-and-capillary-perfus
Comparison of glucose metabolism and cerebral blood flow during cortical motor activation<...
TY - JOUR. T1 - Comparison of glucose metabolism and cerebral blood flow during cortical motor activation. AU - Hallett, M.. AU - Zeffiro, T.. AU - Dubinsky, R. M.. AU - Bierner, S. M.. N1 - Copyright: Copyright 2017 Elsevier B.V., All rights reserved.. PY - 1994. Y1 - 1994. N2 - Regions of cerebral cortex activated in normal subjects making simple, repetitive, voluntary wrist movements were studied with positron emission tomography (PET). The regional cerebral metabolic rate of glucose utilization was studied with 2 [18F]fluoro-2-deoxy-D-glucose (FDG), and regional cerebral blood flow was studied with 15O-labeled water. No significant activation was found with the cerebral metabolic rate studies. Studies of regional cerebral blood flow showed significant activation of the contralateral sensorimotor cortex region of 42%, of the ipsilateral sensorimotor cortex region of 19%, and of the medial frontal cortex of 30% compared with the resting state. Increases in blood flow in the contralateral ...
https://utsouthwestern.pure.elsevier.com/en/publications/comparison-of-glucose-metabolism-and-cerebral-blood-flow-during-c
Laser doppler flowmetry to measure changes in cerebral blood flow - Radcliffe Department of MedicineLaser doppler flowmetry to measure changes in cerebral blood flow - Radcliffe Department of Medicine
Laser Doppler flowmetry (LDF) is a method by which relative cerebral blood flow (CBF) of the cortex can be measured. Although the method is easy to employ, LDF only measures relative CBF, while absolute CBF cannot be quantified. LDF is useful for investigating CBF changes in a number of different applications including neurovascular and stroke research. This chapter will prepare the reader for rodent experiments using LDF with two preparations. The closed skull preparation can be used to monitor CBF with an intact skull, but in adult rats, thinning of the skull is required to obtain an accurate cortical CBF signal. The open skull preparation requires a craniotomy to expose the surface of the brain and the LDF probe is held close to the surface to measure cerebral perfusion. © 2014 Springer Science+Business Media New York.
https://www.rdm.ox.ac.uk/publications/474098
Laser Doppler flowmetry to measure changes in cerebral blood flow. - Radcliffe Department of MedicineLaser Doppler flowmetry to measure changes in cerebral blood flow. - Radcliffe Department of Medicine
Laser Doppler flowmetry (LDF) is a method by which relative cerebral blood flow (CBF) of the cortex can be measured. Although the method is easy to employ, LDF only measures relative CBF, while absolute CBF cannot be quantified. LDF is useful for investigating CBF changes in a number of different applications including neurovascular and stroke research. This chapter will prepare the reader for rodent experiments using LDF with two preparations. The closed skull preparation can be used to monitor CBF with an intact skull, but in adult rats, thinning of the skull is required to obtain an accurate cortical CBF signal. The open skull preparation requires a craniotomy to expose the surface of the brain and the LDF probe is held close to the surface to measure cerebral perfusion.
https://www.rdm.ox.ac.uk/publications/449203
The effects of hypoglycaemia on cerebral blood flow and metabolism in the new-born calf | Meta
1. The effects of insulin hypoglycaemia on cerebral blood flow and metabolism have been examined in unanaesthetized, unrestrained calves between 1 and 26 days after birth. 2. Cerebral blood flow was measured with an inert gas technique using molecular hydrogen, and cerebral metabolism was quantified by determination of arterio-cerebral venous (A--V) concentration differences for oxygen, glucose, lactate, pyruvate, acetoacetate, beta-D-hydroxybutyrate and ammonia. 3. During normoglycaemia the mean (A--V) difference for glucose was close to one sixth that of oxygen, on a molar basis. A small net loss of pyruvate from the brain was found, but there was no significant (A--V) difference for lactate. Arterial concentrations of acetoacetate and beta-D-hydroxybutyrate were low, and no utilization of ketone bodies by the brain was demonstrated. 4. Moderate hypoglycaemia (arterial plasma glucose concentration 1--2 m-mole/l.) had no measurable effect on either cerebral blood flow or metabolism. 5. During ...
https://www.meta.org/papers/the-effects-of-hypoglycaemia-on-cerebral-blood/6987378
Cerebral hemodynamic changes after wartime traumatic brain injury<...Cerebral hemodynamic changes after wartime traumatic brain injury<...
TY - GEN. T1 - Cerebral hemodynamic changes after wartime traumatic brain injury. AU - Razumovsky, Alexander. AU - Tigno, Teodoro. AU - Hochheimer, Sven M.. AU - Stephens, Fred L.. AU - Bell, Randy. AU - Vo, Alexander H.. AU - Severson, Meryl A.. AU - Marshall, Scott A.. AU - Oppenheimer, Stephen M.. AU - Ecker, Robert. AU - Armonda, Rocco A.. PY - 2013. Y1 - 2013. N2 - Traumatic brain injury (TBI) is associated with the severest casualties from Operation Iraqi Freedom (OIF) and Operation Enduring Freedom (OEF). From October 1, 2008, the U.S. Army Medical Department initiated a transcranial Doppler (TCD) ultrasound service for TBI; included patients were retrospectively evaluated for TCD-determined incidence of post-traumatic cerebral vasospasm and intracranial hypertension after wartime TBI. Ninety patients were investigated with daily TCD studies and a comprehensive TCD protocol, and published diagnostic criteria for vasospasm and increased intracranial pressure (ICP) were applied. TCD signs ...
https://researchexperts.utmb.edu/en/publications/cerebral-hemodynamic-changes-after-wartime-traumatic-brain-injury
Validation of the CBF, CBV, and MTT Values by Perfusion MRI in Chronic Occlusive Cerebrovascular Disease: A Comparison with ...
TY - JOUR. T1 - Validation of the CBF, CBV, and MTT Values by Perfusion MRI in Chronic Occlusive Cerebrovascular Disease. T2 - A Comparison with 15O-PET. AU - Kaneko, Koichiro. AU - Kuwabara, Yasuo. AU - Mihara, Futoshi. AU - Yoshiura, Takashi. AU - Nakagawa, Makoto. AU - Tanaka, Atsuo. AU - Sasaki, Masayuki. AU - Koga, Hirofumi. AU - Hayashi, Kazutaka. AU - Honda, Hiroshi. PY - 2004/5. Y1 - 2004/5. N2 - Rationale and Objectives. To evaluate the reliability of cerebral blood flow (CBF), cerebral blood volume (CBV), and mean transit time (MTT) values obtained by deconvolution algorithm perfusion-weighted MR imaging (D-PWI), we compared these values with those obtained by first-moment algorithm perfusion-weighted MR imaging (F-PWI) and 15O-PET. Subjects and Methods. Six healthy volunteers and eleven patients with chronic occlusive cerebrovascular disease were studied with both perfusion-weighted MR imaging and 15O-PET, and region-of-interest analyses were performed. Normalization factors for CBF ...
https://kyushu-u.pure.elsevier.com/en/publications/validation-of-the-cbf-cbv-and-mtt-values-by-perfusion-mri-in-chro
PDF] Continuous monitoring of regional cerebral blood flow: experimental and clinical validation of a novel thermal diffusion...PDF] Continuous monitoring of regional cerebral blood flow: experimental and clinical validation of a novel thermal diffusion...
OBJECT Current clinical neuromonitoring techniques lack adequate surveillance of cerebral perfusion. In this article, a novel thermal diffusion (TD) microprobe is evaluated for the continuous and quantitative assessment of intraparenchymal regional cerebral blood flow (rCBF). METHODS To characterize the temporal resolution of this new technique, rCBF measured using the TD microprobe (TD-rCBF) was compared with rCBF levels measured by laser Doppler (LD) flowmetry during standardized variations of CBF in a sheep model. For validation of absolute values, the microprobe was implanted subcortically (20 mm below the level of dura) into 16 brain-injured patients, and TD-rCBF was compared with simultaneous rCBF measurements obtained using stable xenon-enhanced computerized tomography scanning (sXe-rCBF). The two techniques were compared using linear regression analysis as well as the Bland and Altman method. Stable TD-rCBF measurements could be obtained throughout all 3- to 5-hour sheep experiments. During
https://www.semanticscholar.org/paper/Continuous-monitoring-of-regional-cerebral-blood-of-Vajkoczy-R%C3%B3th/09e21f38829954c72d51459397af8819ee3d9815
Correlation of Regional Cerebral Blood Flow (rCBF) with EEG Changes During Isoflurane Anesthesia for Carotid Endarterectomy |...Correlation of Regional Cerebral Blood Flow (rCBF) with EEG Changes During Isoflurane Anesthesia for Carotid Endarterectomy |...
Joseph M. Messick, Brian Casement, Frank W. Sharbrough, Leslie N. Milde, John D. Michenfelder, Thoralf M. Sundt; Correlation of Regional Cerebral Blood Flow (rCBF) with EEG Changes During Isoflurane Anesthesia for Carotid Endarterectomy: Critical rCBF. Anesthesiology 1987; 66:344-349 doi: https://doi.org/10.1097/00000542-198703000-00014. Download citation file:. ...
https://pubs.asahq.org/anesthesiology/article/66/3/344/29000/Correlation-of-Regional-Cerebral-Blood-Flow-rCBF
Luxury | Marketplace | Marketing | Online, Branding, Promotion | Luxury AbodeLuxury | Marketplace | Marketing | Online, Branding, Promotion | Luxury Abode
As the worlds truly holistic luxury marketplace, we are deploying some of the best technologies to provide the best luxury experience to consumers online in terms of information, offering exciting luxury deals and unearthing new luxury brands, etc.. You can work with Luxury Abode to advertise your luxury brand, to sell your luxury products, to engage with consumers using our social media marketing, to develop your luxury brand digitally, to create a luxury website and essentially synergize with our energy in all possible ways to reach the pinnacle of luxury.. Apart from this, as a leading global online luxury marketplace, we aim to help new luxury brands discover and reach new consumers across the globe. In the same way as one of the most innovative online luxury marketplace, Luxury Abode aims to help consumers connect with luxury brands in a more meaningful and interactive manner. Our aim is not to be the worlds largest luxury marketplace nor is it to be the luxury marketplace for the richest ...
https://www.luxuryabode.com/
Cerebral blood flow measurements in subarachnoid haemorrhage with an intravenous isotope technique : methodological studies :...Cerebral blood flow measurements in subarachnoid haemorrhage with an intravenous isotope technique : methodological studies :...
Cerebral blood flow measurements in subarachnoid haemorrhage with an intravenous isotope technique: methodological studies : the significance of cerebral blood flow determinations in the timing of surgery of arterial aneurysm ...
http://uu.diva-portal.org/smash/record.jsf?pid=diva2:296275
Inversion of neurovascular coupling after subarachnoid hemorrhage in vivo - Munich Cluster for Systems Neurology - LMU Munich
Abstract. Subarachnoid hemorrhage (SAH) induces acute changes in the cerebral microcirculation. Recent findings ex vivo suggest neurovascular coupling (NVC), the process that increases cerebral blood flow upon neuronal activity, is also impaired after SAH. The aim of the current study was to investigate whether this occurs also in vivo. C57BL/6 mice were subjected to either sham surgery or SAH by filament perforation. Twenty-four hours later NVC was tested by forepaw stimulation and CO2 reactivity by inhalation of 10% CO2. Vessel diameter was assessed in vivo by two-photon microscopy. NVC was also investigated ex vivo using brain slices. Cerebral arterioles of sham-operated mice dilated to 130% of baseline upon CO2 inhalation or forepaw stimulation and cerebral blood flow (CBF) increased. Following SAH, however, CO2 reactivity was completely lost and the majority of cerebral arterioles showed paradoxical constriction in vivo and ex vivo resulting in a reduced CBF response. As previous results ...
https://www.synergy-munich.de/publications/2017/balbi.html
Repositorio da Producao Cientifica e Intelectual da Unicamp: Elevated thalamic and prefrontal regional cerebral blood flow in...Repositorio da Producao Cientifica e Intelectual da Unicamp: Elevated thalamic and prefrontal regional cerebral blood flow in...
Functional neuroimaging studies have pointed to a possible role of cerebral circuits involving the prefrontal and anterior cingulate cortices, the striatum, and thalamus in the pathophysiology of obsessive-compulsive disorder (OCD). Regional cerebral blood flow (rCBF) of 16 drug-free Brazilian patients with OCD and 17 healthy subjects matched for age, gender, handedness and level of education was measured with [99m-Tc] HMPAO single photon emission computed tomography. Analysis of covariance identified four regions of interest with significantly higher rCBF: the right superior and inferior frontal cortex and the right and left thalamus. Positive correlations between symptom severity measured by Clinical Global Impression scores and rCBF were found in the right and left inferior frontal lobes and in the right basal ganglia. Compulsive behavior was inversely correlated with rCBF in the right thalamus, and duration of illness correlated positively with rCBF in the right and left superior frontal ...
http://repositorio.unicamp.br/jspui/handle/REPOSIP/64656
Perfusion imaging with compensation for asymmetric magnetization transfer effects. - Wellcome Centre for Integrative...
The effects of off-resonance radio-frequency irradiation on the intensity of the MR signal from water protons in the cat brain are asymmetric around the chemical shift of the water signal. This asymmetry, which could arise from a shift in the magnetization transfer spectrum approximately 1.5 ppm upfield from the solvent water signal, must be taken into account to compensate for magnetization transfer effects inherent in arterial spin tagging approaches that use a single radio-frequency coil. Two approaches that either correct for, or circumvent, the apparent upfield shift of the magnetization transfer spectrum are presented, and a perfusion image of the cat brain, using flow-induced adiabatic inversion of arterial water protons, is presented. Other problems in obtaining quantitative cerebral blood flow values using the arterial spin tagging approach are discussed.
https://www.win.ox.ac.uk/publications/894895
Regional cerebral blood flow during auditory recall in 47 subjects exposed to assaultive and non-assaultive trauma and...Regional cerebral blood flow during auditory recall in 47 subjects exposed to assaultive and non-assaultive trauma and...
Objective Psychological trauma leads to Post Traumatic Stress Disorder (PTSD) in susceptible subjects. The aim of this study was to investigate the differences in regional cerebral blood flow (rCBF) between two groups of subjects exposed to different types of traumatic stressor either developing or not PTSD. Method Twenty subjects developing (S) and 27 not developing (NS) PTSD after being exposed to either earlier person-under-the-train accident (NA) or being assaulted in the underground enviroment (A) were included in the study. 99mTc-HMPAO SPECT was performed and the uptake in 29 regions of the brain (VOIs), bilaterally, was assessed. rCBF distribution was compared, using analysis of variance (ANOVA), between groups (S/NS) and type (A/NA) during a situation involving an auditory evoked re-experiencing of the traumatic event. Discriminant analysis was applied to test the concordance between clinical diagnosis and SPECT findings. Results In the general analyses significant differences were found ...
https://www.istc.cnr.it/it/content/regional-cerebral-blood-flow-during-auditory-recall-47-subjects-exposed-assaultive-and-non
KAKEN - Research Projects | Development of Quantitative Cerebral Blood Flow and Oxygen Metabolism using O-17 Water and Oxygen...KAKEN - Research Projects | Development of Quantitative Cerebral Blood Flow and Oxygen Metabolism using O-17 Water and Oxygen...
Principal Investigator：Kudo Kohsuke, Project Period (FY)：2014-04-01 - 2017-03-31, Research Category：Grant-in-Aid for Scientific Research (B), Section：一般, Research Field：Radiation science
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-26293269/
Long term evaluation of brain perfusion with magnetic resonance in high flow extracranial-intracranial saphenous graft bypass<...
TY - JOUR. T1 - Long term evaluation of brain perfusion with magnetic resonance in high flow extracranial-intracranial saphenous graft bypass. AU - Bozzao, Alessandro. AU - Fasoli, Fabrizio. AU - Finocchi, Vanina. AU - Santoro, Giuseppe. AU - Romano, Andrea. AU - Fantozzi, Luigi Maria. PY - 2007/1. Y1 - 2007/1. N2 - Assessment was made of the cerebral vascular haemodynamic parameters in patients with a high-flow extra-intracranial (EC-IC) bypass performed for therapeutic occlusion of the internal carotid artery (ICA). Sixteen patients with ICA occlusion and EC-IC bypass (time interval from surgery 1-6 years) underwent MRI. Perfusion-weighted magnetic resonance imaging (PW-MRI) sequences were performed without the use of an arterial input function. The relative cerebral blood volume (rCBV), mean transit time (MTT) and relative cerebral blood flow (rCBF) were evaluated in all patients at the level of the basal ganglia, centrum semiovale and cortex in both hemispheres. Statistically significant ...
https://moh-it.pure.elsevier.com/en/publications/long-term-evaluation-of-brain-perfusion-with-magnetic-resonance-i
Perfusion imaging: quantitative cerebral blood flow mapping in humans using magnetic resonance imaging. - Oxford Neuroscience
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https://www.neuroscience.ox.ac.uk/publications/894884
Brain Blood Flow Modulates the Neurotoxic Action of Hyperbaric Oxygen via Neuronal and Endothelial Nitric Oxide<...
TY - JOUR. T1 - Brain Blood Flow Modulates the Neurotoxic Action of Hyperbaric Oxygen via Neuronal and Endothelial Nitric Oxide. AU - Moskvin, A. N.. AU - Zhilyaev, S. Yu. AU - Sharapov, O. I.. AU - Platonova, T. F.. AU - Gutsaeva, Diana Raisovna. AU - Kostkin, V. B.. AU - Demchenko, I. T.. PY - 2003/11/1. Y1 - 2003/11/1. N2 - Studies on conscious rats with inhibition of NO synthase were used to assess the dynamics of brain blood flow and EEG traces during hyperbaric oxygenation at 4 or 5 atm. Oxygen at a pressure of 4 atm induced cerebral vasoconstriction in intact animals and decreased blood flow by 11-18% (p , 0.05) during 60-min exposure to hyperbaric oxygenation. Paroxysmal EEG activity and oxygen convulsions did not occur in rats at 4 atm of O2. At 5 atm, convulsive activity appeared on the EEG at 41 ± 1.9 min, and blood flow decreased significantly during the first 20 min; blood flow increased by 23 ± 9%, as compared with controls, (p , 0.01) before the appearance of convulsions on the ...
https://augusta.pure.elsevier.com/en/publications/brain-blood-flow-modulates-the-neurotoxic-action-of-hyperbaric-ox
Dr. Philip Ainslie | ICORDDr. Philip Ainslie | ICORD
Cardiovascular health; cerebral blood flow regulation; cerebrovascular function Dr. Philip Ainslies research is focused on the integrated mechanisms that regulate human cerebral blood flow in health and disease, the influence of environmental stress, and the effects of exercise training on cerebrovascular function.. Dr. Philip Ainslie is a Professor in the School of Health and Exercise Sciences at UBC Okanagan, the Co-Director of the Centre for Heart, Lung & Vascular Health, and an ICORD Investigator. His Ph.D. (in exercise physiology & metabolism) was a collaborative project between the Liverpool John Moores University, University of Manchester and University of Oxford. Following completion of a post-doctoral research fellowship at the University of Calgary he began a faculty position in 2005, as Lecturer and Principal Investigator in the Department of Physiology at the University of Otago, New Zealand. Here, he established his independent research program, focusing on the integrative ...
http://icord.org/researchers/dr-philip-ainslie/
Effect of backrest position on intracranial pressure and cerebral perfusion pressure in individuals with brain injury: a...Effect of backrest position on intracranial pressure and cerebral perfusion pressure in individuals with brain injury: a...
Free Online Library: Effect of backrest position on intracranial pressure and cerebral perfusion pressure in individuals with brain injury: a systematic review. by Journal of Neuroscience Nursing; Health care industry Brain injuries Care and treatment Primary care nursing Methods Primary nursing
https://www.thefreelibrary.com/Effect+of+backrest+position+on+intracranial+pressure+and+cerebral+...-a0123707216
Designing and comparing optimized pseudo-continuous Arterial Spin Labeling protocols for measurement of cerebral blood flow. -...
Arterial Spin Labeling (ASL) is a non-invasive, non-contrast, perfusion imaging technique which is inherently SNR limited. It is, therefore, important to carefully design scan protocols to ensure accurate measurements. Many pseudo-continuous ASL (PCASL) protocol designs have been proposed for measuring cerebral blood flow (CBF), but it has not yet been demonstrated which design offers the most accurate and repeatable CBF measurements. In this study, a wide range of literature PCASL protocols were first optimized for CBF accuracy and then compared using Monte Carlo simulations and in vivo experiments. The protocols included single-delay, sequential and time-encoded multi-timepoint protocols, and several novel protocol designs, which are hybrids of time-encoded and sequential multi-timepoint protocols. It was found that several multi-timepoint protocols produced more confident, accurate, and repeatable CBF estimates than the single-delay protocol, while also generating maps of arterial transit time. Of
https://www.win.ox.ac.uk/publications/1130692
When the air hits your brain: Cerebral autoregulation of brain oxygenation during aerobic exercise allows transient...
TY - JOUR. T1 - When the air hits your brain. T2 - Cerebral autoregulation of brain oxygenation during aerobic exercise allows transient hyperoxygenation: Case report. AU - Bollo, Robert J.. AU - Williams, Susan C.. AU - Peskin, Charles. AU - Samadani, Uzma. PY - 2010/8. Y1 - 2010/8. N2 - OBJECTIVE: Cerebral autoregulation maintains a relatively stable cerebral blood flow over a range of perfusion pressures. During exercise, regional cerebral blood flow may be elevated in particular areas of the brain. This case report presents the impact of aerobic exercise on intracranially measured pressure and brain tissue oxygenation in an adult human. CLINCIAL PRESENTATION: A 30-year-old man with idiopathic intracranial hypertension treated with cerebrospinal fluid diversion was monitored with a Licox intracranial brain oxygen and pressure monitor (Integra NeuroSciences Corporation, Plainsboro, New Jersey) for refractory nonpostural headaches exacerbated after exercise. He performed trials of running and ...
https://nyu-staging.pure.elsevier.com/en/publications/when-the-air-hits-your-brain-cerebral-autoregulation-of-brain-oxy
Repositório Institucional UNIFESP: Effects of heart failure on cerebral blood flow in copd: rest and exercise
Cerebral blood flow (CBF) and oxygenation (COx) are generally well-preserved in COPD. It is unknown whether prevalent cardiovascular co-morbidities, such as heart failure, may impair CBF and COx responses to exertion. Eighteen males with moderate-to-severe COPD (8 with and 10 without overlapping heart failure) underwent a progressive exercise test with pre-frontal CBF and COx measurements (indocyanine green and near-infrared spectroscopy). Mean arterial pressure and cardiac output were lower from rest to exercise in overlap. Only COPD patients demonstrated an increase in arterialized PCO2 towards the end of progressive exercise. CBF index was consistently higher and increased further by similar to 40% during exercise in COPD whereas a similar to 10% reduction was observed in overlap. COx was lower in overlap despite preserved arterial oxygenation. In conclusion, heart failure introduces pronounced negative effects on CBF and COx in COPD which may be associated with clinically relevant outcomes, ...
http://repositorio.unifesp.br/jspui/handle/11600/49183?mode=full
Vinpocetine 5mg N50 - Shop Scenar Denas | Only Best For You
The mechanism of action of vinpocetine is composed of several elements: it improves cerebral blood flow and metabolism, has a beneficial effect on the rheological properties of blood. The neuroprotective action is realized by reducing the adverse cytotoxic effect of excitatory amino acids. Improves the exchange of serotonin and norepinephrine in the brain, it stimulates the noradrenergic neurotransmitter systems and has an antioxidant effect. It improves the microcirculation in the brain by inhibiting platelet aggregation, reducing the pathologically increased blood viscosity, increase the deformability of red blood cells and the inhibition of the reuptake of adenoeina; promotes oxygen transfer into the cells by reducing the affinity of erythrocytes thereto. Selectively increases cerebral blood flow by reducing the cerebral vascular resistance without a significant impact on system performance circulatory (blood pressure (BP), cardiac output, heart rate, total peripheral vascular resistance); It ...
http://scenar-denas.com/product/vinpocetine-5mg-n50
Clarient Diagnostics has licensed cancer biomarker; NASA-sponsored bone test could spot osteoporosis and cancer; | FierceBiotechClarient Diagnostics has licensed cancer biomarker; NASA-sponsored bone test could spot osteoporosis and cancer; | FierceBiotech
| Arterial spin labeling (ASL) MRI, which measures cerebral blood flow, could act as a biomarker in Alzheimers disease. Abstract | GE Healthcare ($GE) company Clarient Diagnostic Services...
https://www.fiercebiotech.com/medical-devices/clarient-diagnostics-has-licensed-cancer-biomarker-nasa-sponsored-bone-test-could
Dynamic pressure - Flow relationship of the cerebral circulation during acute increase in arterial pressure<...
TY - JOUR. T1 - Dynamic pressure - Flow relationship of the cerebral circulation during acute increase in arterial pressure. AU - Zhang, Rong. AU - Behbehani, Khosrow. AU - Levine, Benjamin D.. PY - 2009. Y1 - 2009. N2 - The physiological mechanism(s) for the regulation of the dynamic pressure-flow relationship of the cerebral circulation are not well understood. We studied the effects of acute cerebral vasoconstriction on the transfer function between spontaneous changes in blood pressure (BP) and cerebral blood flow velocity (CBFV) in 13 healthy subjects (30 ± 7 years). CBFV was measured in the middle cerebral artery using transcranial Doppler. BP was increased stepwise with phenylephrine infusion at 0.5, 1.0 and 2.0 μg kg-1 min-1. Phenylephrine increased BP by 11, 23 and 37% from baseline, while CBFV increased (11%) only with the highest increase in BP. Cerebrovascular resistance index (BP/CBFV) increased progressively by 6, 17 and 23%, demonstrating effective steady-state autoregulation. ...
https://utsouthwestern.pure.elsevier.com/en/publications/dynamic-pressure-flow-relationship-of-the-cerebral-circulation-du
Endothelial influences on cerebrovascular tone<...
TY - JOUR. T1 - Endothelial influences on cerebrovascular tone. AU - Andresen, Jon. AU - Shafi, Nadeem. AU - Bryan, Robert M.. PY - 2006/1/1. Y1 - 2006/1/1. N2 - The cerebrovascular endothelium exerts a profound influence on cerebral vessels and cerebral blood flow. This review summarizes current knowledge of various dilator and constrictor mechanisms intrinsic to the cerebrovascular endothelium. The endothelium contributes to the resting tone of cerebral arteries and arterioles by tonically releasing nitric oxide (NO • ). Dilations can occur by stimulated release of NO • , endothelium-derived hyperpolarization factor, or prostanoids. During pathological conditions, the dilator influence of the endothelium can turn to that of constriction by a variety of mechanisms, including decreased NO • bioavailability and release of endothelin-1. The endothelium may participate in neurovascular coupling by conducting local dilations to upstream arteries. Further study of the cerebrovascular ...
https://uthsc.pure.elsevier.com/en/publications/endothelial-influences-on-cerebrovascular-tone
Plus itPlus it
FIG. 1. Regional cerebral blood flow changes during hypoglycemia illustrating greater synaptic activity in bilateral dorsal midline thalamus on day 2, following ∼24 h of interval interprandial hypoglycemia, compared with day 1. These are combined subtraction images from all PET scans from all nine subjects superimposed on the combined MR image. The color scales show changes relative to mean global blood flow. A maximum of 12% is used for all scales. However, the maximum change for day 2 was 18% compared with 10% on day 1. A: Mid-sagittal slices. B: Coronal slices at the level of the paraventricular nuclei (y = −19) with the left of the brain on the left (33). ...
https://diabetes.diabetesjournals.org/content/57/2/470/F1
Cerebral circulationCerebral circulation
"The cerebral circulation and cerebrovascular disease I: Anatomy". Brain Circulation. 3 (2): 45-56. doi:10.4103/bc.bc_10_17. PMC ... The following description is based on idealized human cerebral circulation. The pattern of circulation and its nomenclature ... The anterior cerebral circulation is the blood supply to the anterior portion of the brain including eyes. It is supplied by ... Cerebral circulation is the movement of blood through a network of cerebral arteries and veins supplying the brain. The rate of ...
https://en.wikipedia.org/wiki/Cerebral_circulation
Gaseous mediatorGaseous mediator
... gaseous messengers in cerebrovascular circulation". J. Appl. Physiol. 100 (3): 1065-76. doi:10.1152/japplphysiol.00793.2005. ...
https://en.wikipedia.org/wiki/Gaseous_mediator
Leptomeningeal collateral circulationLeptomeningeal collateral circulation
"Computer Modeling of Anterior Circulation Stroke: Proof of Concept in Cerebrovascular Occlusion". Frontiers in Neurology. 5: ... Leptomeningeal circulation has been observed in mice and rats during experiments to assess changes associated with disease and ... The leptomeningeal collateral circulation (also known as leptomeningeal anastomoses or pial collaterals) is a network of small ... The Human Brain Circulation: Functional Changes in Disease. Vascular Biomedicine. Humana Press. pp. 237-246. doi:10.1007/978-1- ...
https://en.wikipedia.org/wiki/Leptomeningeal_collateral_circulation
Brain ischemiaBrain ischemia
Moyamoya disease is an extremely rare cerebrovascular condition that limits blood circulation to the brain, consequently ... If sufficient circulation is restored within a short period of time, symptoms may be transient. However, if a significant ...
https://en.wikipedia.org/wiki/Brain_ischemia
Center for Cerebrovascular ResearchCenter for Cerebrovascular Research
San Francisco is a collective of faculty and staff investigating matters related to cerebral circulation, particularly ... The Center for Cerebrovascular Research was established at the University of California San Francisco in 2000.[citation needed ... The Center for Cerebrovascular Research at the University of California, ... cerebrovascular disease resulting from narrowing of major blood vessels in the brain and vascular malformation of the brain. ...
https://en.wikipedia.org/wiki/Center_for_Cerebrovascular_Research
List of MeSH codes (G09)List of MeSH codes (G09)
... blood circulation MeSH G09.330.582.163.159 - cerebrovascular circulation MeSH G09.330.582.163.248 - collateral circulation MeSH ... pulmonary circulation MeSH G09.330.582.163.780 - regional blood flow MeSH G09.330.582.163.812 - renal circulation MeSH G09.330. ... splanchnic circulation MeSH G09.330.582.163.881.552 - liver circulation MeSH G09.330.582.400 - hemodynamic processes MeSH ... pulmonary circulation MeSH G09.772.770.755 - respiration MeSH G09.772.770.755.700 - respiratory mechanics MeSH G09.772.770.755. ...
https://en.wikipedia.org/wiki/List_of_MeSH_codes_(G09)
ICAM-1ICAM-1
Frijns CJ, Kappelle LJ (Aug 2002). "Inflammatory cell adhesion molecules in ischemic cerebrovascular disease". Stroke: A ... Journal of Cerebral Circulation. 33 (8): 2115-22. doi:10.1161/01.STR.0000021902.33129.69. PMID 12154274. Annels NE, Mansfield D ...
https://en.wikipedia.org/wiki/ICAM-1
Smoking banSmoking ban
... cerebrovascular, and respiratory diseases: a meta-analysis". Circulation. 126 (18): 2177-83. doi:10.1161/CIRCULATIONAHA. ... cerebrovascular, and respiratory diseases, and that "More comprehensive laws were associated with larger changes in risk." The ...
https://en.wikipedia.org/wiki/Smoking_ban
Cerebral organoidCerebral organoid
Newer methods allow development of cerebrovascular organoids, and micro pumps to provide circulation through them are being ...
https://en.wikipedia.org/wiki/Cerebral_organoid
Complement component 4BComplement component 4B
A Journal of Cerebral Circulation. 31 (11): 2648-52. doi:10.1161/01.STR.31.11.2648. PMID 11062289. Dragon-Durey MA, Rougier N, ... "Frequencies of certain complement protein alleles and serum levels of anti-heat-shock protein antibodies in cerebrovascular ...
https://en.wikipedia.org/wiki/Complement_component_4B
Cerebrovascular diseaseCerebrovascular disease
... disease includes a variety of medical conditions that affect the blood vessels of the brain and the cerebral circulation. ... The incidence of cerebrovascular disease increases as an individual ages. Causes of acquired cerebrovascular disease include ... Other symptoms of cerebrovascular disease include migraines, seizures, epilepsy, or cognitive decline. However, cerebrovascular ... Cerebrovascular diseases can also present less commonly with headache or seizures. Any of these diseases can result in vascular ...
https://en.wikipedia.org/wiki/Cerebrovascular_disease
List of ICD-9 codes 740-759: congenital anomaliesList of ICD-9 codes 740-759: congenital anomalies
... system 747.81 Congenital anomalies of cerebrovascular system 747.82 Spinal vessel anomaly 747.83 Persistent fetal circulation ...
https://en.wikipedia.org/wiki/List_of_ICD-9_codes_740–759:_congenital_anomalies
Subclavian arterySubclavian artery
Posterior Circulation: Large Artery Occlusive Disease and Embolism", Primer on Cerebrovascular Diseases (Second Edition), San ...
https://en.wikipedia.org/wiki/Subclavian_artery
Antiplatelet drugAntiplatelet drug
They are effective in the arterial circulation where anticoagulants have little effect.[citation needed] They are widely used ... in primary and secondary prevention of thrombotic cerebrovascular or cardiovascular disease. Antiplatelet therapy with one or ...
https://en.wikipedia.org/wiki/Antiplatelet_drug
Ana Catarina FonsecaAna Catarina Fonseca
Her main research interests are cryptogenic stroke, heart-brain interactions (cerebrovascular disease), and precision medicine ... Circulation, Neurology, European Journal of Neurology, Journal of the Neurological Sciences, Acta Neurologica Scandinavica, ... Journal of Stroke and Cerebrovascular Diseases, European Neurology, International Journal of Stroke Research, JAMA Neurology, ...
https://en.wikipedia.org/wiki/Ana_Catarina_Fonseca
Silent strokeSilent stroke
The Dutch TIA Trial Study Group". Stroke: A Journal of Cerebral Circulation. 23 (9): 1220-4. doi:10.1161/01.STR.23.9.1220. PMID ... Cerebrovascular Diseases. 16 (3): 280-5. doi:10.1159/000071128. PMID 12865617. S2CID 33095581. Vermeer, SE; Koudstaal, PJ; ... CHS Collaborative Research Group". Stroke: A Journal of Cerebral Circulation. 28 (6): 1158-64. doi:10.1161/01.STR.28.6.1158. ... Relationship with index-stroke subtype, vascular risk factors, and mortality". Stroke: A Journal of Cerebral Circulation. 25 ( ...
https://en.wikipedia.org/wiki/Silent_stroke
Cerebral blood volumeCerebral blood volume
Lassen, N. A. (June 1984). "Cerebral Blood Flow and Blood Volume Tomography by SPECT in Cerebrovascular Disease". Clinical ... thereby predicting cerebral circulation. Leenders, K. L.; Perani, D.; Lammertsma, A. A.; Heather, J. D.; Buckingham, P.; Jones ... It is a new method for studying hemodynamic changes in brain pathophysiology, including clinical studies of cerebrovascular ... Both cerebral blood volume and cerebral blood flow depend on several important parameters, including cerebrovascular resistance ...
https://en.wikipedia.org/wiki/Cerebral_blood_volume
Intracranial aneurysmIntracranial aneurysm
An intracranial aneurysm, also known as a brain aneurysm, is a cerebrovascular disorder in which weakness in the wall of a ... These cells initially invade the subarachnoid space from the circulation in order to phagocytose the hemorrhaged red blood ... Aneurysms in the posterior circulation (basilar artery, vertebral arteries and posterior communicating artery) have a higher ... and passed through blood vessels into the cerebral circulation and the aneurysm. Coils are pushed into the aneurysm, or ...
https://en.wikipedia.org/wiki/Intracranial_aneurysm
Cerebral angiographyCerebral angiography
To image the anterior cerebral circulation such as internal and external carotid arteries and its branches, AP, Towne's and ... Some risk factors of complications are if the subject is having subarachnoid haemorrhage, atherosclerotic cerebrovascular ... To image the posterior circulation, such as vertebral and basilar arteries, AP, Towne's view, lateral projections near the back ... Ross IB, Luzardo GD (February 2006). "Direct access to the carotid circulation by cut down for endovascular neuro-interventions ...
https://en.wikipedia.org/wiki/Cerebral_angiography
Cytochrome b-245, alpha polypeptideCytochrome b-245, alpha polypeptide
Li P, Qiu T, Qin C (19 January 2015). "NADPH oxidase p22phox C242T polymorphism and ischemic cerebrovascular disease: an ... Circulation. 97 (2): 135-7. doi:10.1161/01.cir.97.2.135. PMID 9445163. Gardemann A, Mages P, Katz N, Tillmanns H, Haberbosch W ... hypertension atherosclerosis or diabetes and its complications and ischemic cerebrovascular diseases. The results from these ...
https://en.wikipedia.org/wiki/Cytochrome_b-245,_alpha_polypeptide
Orthostatic hypertensionOrthostatic hypertension
2 (3). Streeten, D.H.P. (1987). Orthostatic Disorders of the Circulation. New York: Plenum Medical. p. 116. ISBN 978-1-4684- ... Increased occurrence of silent cerebrovascular ischemia Systolic orthostatic hypertension increases stroke risk. Orthostatic ... Circulation Journal. 73 (6): 1002-1007. doi:10.1253/circj.cj-09-0286. PMID 19430163. Yatsuya H, Folsom AR, Alonso A, Gottesman ... Japanese Circulation Journal. 52 (12): 1408-1414. doi:10.1253/jcj.52.1408. PMID 2977192. Takada Y, Shimizu H, Kazatani Y, ...
https://en.wikipedia.org/wiki/Orthostatic_hypertension
Carotid endarterectomyCarotid endarterectomy
Circulation. 118 (25): 2852-2859. doi:10.1161/circulationaha.108.191175. PMID 19106407. Watanabe, J; Ogata, T; Hamada, O; ... Journal of Stroke and Cerebrovascular Diseases. 23 (6): 1332-6. doi:10.1016/j.jstrokecerebrovasdis.2013.11.004. PMID 24462461. ... carotid artery occlusion The person has a previous complete hemispheric stroke on the ipsilateral and complete cerebrovascular ...
https://en.wikipedia.org/wiki/Carotid_endarterectomy
Intima-media thicknessIntima-media thickness
Circulation. 74 (6): 1399-1495. doi:10.1161/01.cir.74.6.1399. PMID 3536154. Lorenz MW, Markus HS, Bots ML, Rosvall M, Sitzer M ... Cerebrovascular Diseases. 34 (4): 290-296. doi:10.1159/000343145. ISSN 1421-9786. PMC 3760791. PMID 23128470. Dalla Pozza, ... Circulation Journal. 69 (8): 903-907. doi:10.1253/circj.69.903. ISSN 1346-9843. PMID 16041157. Touboul, P.-J.; Hennerici, M. G ... Circulation. 115 (4): 459-67. doi:10.1161/CIRCULATIONAHA.106.628875. PMID 17242284. Costanzo P, Perrone-Filardi P, Vassallo E, ...
https://en.wikipedia.org/wiki/Intima-media_thickness
Blood pressureBlood pressure
Differences in mean blood pressure drive the flow of blood around the circulation. The rate of mean blood flow depends on both ... "Long-term Blood Pressure Fluctuation and Cerebrovascular Disease in an Elderly Cohort". Archives of Neurology. 67 (5): 564-69. ... The blood pressure in the circulation is principally due to the pumping action of the heart. However, blood pressure is also ... Mean blood pressure drops over the whole circulation, although most of the fall occurs along the small arteries and arterioles ...
https://en.wikipedia.org/wiki/Blood_pressure
Walter DandyWalter Dandy
... is a cerebrovascular neurosurgeon and the director of the Division of Cerebrovascular Neurosurgery [3], the field created by ... In 1913 and 1914, Dandy and Kenneth D. Blackfan published two landmark papers on the production, circulation, and absorption of ... which marked the birth of cerebrovascular neurosurgery. During his 40-year medical career, Dandy published five books and more ... including the description of the circulation of cerebrospinal fluid in the brain, surgical treatment of hydrocephalus, the ...
https://en.wikipedia.org/wiki/Walter_Dandy
AutoregulationAutoregulation
In this way, the same flow through the coronary circulation is maintained over a range of pressures. This part of coronary ... Paulson, O. B.; S. Strandgaard; L. Edvinsson (1990). "Cerebral autoregulation". Cerebrovascular and Brain Metabolism Reviews. 2 ... If a sufficient flow of oxygen is met and the resistance in the coronary circulation rises (perhaps due to vasoconstriction), ... Sarnoff SJ, Mitchell JH, Gilmore JP, Remensnyder JP (1960). "Homeometric autoregulation in the heart" (PDF). Circulation ...
https://en.wikipedia.org/wiki/Autoregulation
Muse cellMuse cell
Circulation Journal. 82 (2): 561-571. doi:10.1253/circj.CJ-17-0552. PMID 28931784. Cosset, Jean Marc (2002). "ESTRO Breur Gold ... Journal of Stroke and Cerebrovascular Diseases. 25 (6): 1473-1481. doi:10.1016/j.jstrokecerebrovasdis.2015.12.033. ISSN 1532- ... Circulation Research. 122 (8): 1069-1083. doi:10.1161/CIRCRESAHA.117.311648. PMID 29475983. Uchida, Hiroki; Niizuma, Kuniyasu; ... Journal of Stroke and Cerebrovascular Diseases. 25 (6): 1473-81. doi:10.1016/j.jstrokecerebrovasdis.2015.12.033. PMID 27019988 ...
https://en.wikipedia.org/wiki/Muse_cell
EperisoneEperisone
Spastic paralysis in conditions such as cerebrovascular disease Spastic spinal paralysis Cervical spondylosis Postoperative ... improvement of circulation, and suppression of the pain reflex. The drug inhibits the vicious circle of myotonia by decreasing ... and facilitating muscle movement Eperisone also improves dizziness and tinnitus associated with cerebrovascular disorders or ...
https://en.wikipedia.org/wiki/Eperisone
Xanthine oxidaseXanthine oxidase
Zimmet JM, Hare JM (October 2006). "Nitroso-redox interactions in the cardiovascular system". Circulation. 114 (14): 1531-44. ... "The potential for xanthine oxidase inhibition in the prevention and treatment of cardiovascular and cerebrovascular disease". ...
https://en.wikipedia.org/wiki/Xanthine_oxidase
Watershed strokeWatershed stroke
... partial anterior circulation infarct (PACI), lacunar infarct (LACI) or posterior circulation infarct (POCI). These four ... Bamford, J.M. (2000). "The Role of the Clinical Examination in the Subclassification of Stroke". Cerebrovascular Diseases. 10 ( ... On the other hand, they often detach, move into blood circulation, and eventually block smaller downstream branches of arteries ... Based on the extent of the symptoms, the stroke episode is classified as total anterior circulation infarct (TACI), ...
https://en.wikipedia.org/wiki/Watershed_stroke
List of ICD-9 codes 390-459: diseases of the circulatory systemList of ICD-9 codes 390-459: diseases of the circulatory system
436 Acute but ill-defined cerebrovascular disease 437 Other and ill-defined cerebrovascular disease 437.0 Cerebral ... of pulmonary artery 417.8 Other specified diseases of pulmonary circulation 417.9 Unspecified disease of pulmonary circulation ... 438.8 Other late effects of cerebrovascular disease 438.81 Apraxia cerebrovascular disease 438.82 Dysphagia cerebrovascular ... chronic pulmonary heart diseases 416.9 Chronic pulmonary heart disease unspecified 417 Other diseases of pulmonary circulation ...
https://en.wikipedia.org/wiki/List_of_ICD-9_codes_390–459:_diseases_of_the_circulatory_system
PheochromocytomaPheochromocytoma
Cerebrovascular Accident (Stroke): Multiple reports have detailed transient ischemic attacks or strokes in patients with a ... Japanese Circulation Journal. 57 (1): 84-90. doi:10.1253/jcj.57.84. PMID 8437346. Celik H, Celik O, Guldiken S, Inal V, Puyan ... Dagartzikas MI, Sprague K, Carter G, Tobias JD (February 2002). "Cerebrovascular event, dilated cardiomyopathy, and ...
https://en.wikipedia.org/wiki/Pheochromocytoma
Cervical artery dissectionCervical artery dissection
FMC: Cerebrovascular diseases. 95 (12): 1151-1161. doi:10.1016/j.diii.2014.10.003. PMID 25632417. Arnold M, Kappeler L, ... Liebeskind DS (September 2003). "Collateral circulation". Stroke. 34 (9): 2279-2284. doi:10.1161/01.STR.0000086465.41263.06. ... as the bilateral circulation continues perfusing the brain. Thrombus formation is the natural physiologic response to the ...
https://en.wikipedia.org/wiki/Cervical_artery_dissection
Biofluid dynamicsBiofluid dynamics
The rest of the blood flow loop is called systemic circulation system. The pulmonary and systemic circulations take the blood ... Different types of Cerebrovascular disease, Heart Failure, Coronary Heart diseases and Myocardial infarction or Heart attacks. ... The pulmonary and the systemic circulations are the two parts of the vasculature. The pulmonary circulation system consists of ... The systemic circulation is responsible for taking the oxygenated blood to various organs and tissues via the arterial tree ...
https://en.wikipedia.org/wiki/Biofluid_dynamics
DyslipidemiaDyslipidemia
Circulation 1965;31:321-327. Vijan, Sandeep (February 28, 2020). "Screening for lipid disorders in adults". UpToDate. Retrieved ... cerebrovascular disease, and peripheral artery disease. Although dyslipidemia is a risk factor for ASCVD, abnormal levels don't ... Circulation. 140 (11): e563-e595. doi:10.1161/CIR.0000000000000677. ISSN 0009-7322. PMC 8351755. PMID 30879339. Pearson, G. J ... Circulation. 140 (11): e563-e595. doi:10.1161/CIR.0000000000000677. ISSN 0009-7322. PMC 8351755. PMID 30879339. Istvan, Eva S ...
https://en.wikipedia.org/wiki/Dyslipidemia
Postperfusion syndromePostperfusion syndrome
published in Circulation found no significant difference in the incidence of cognitive dysfunction 3 months after either OPCAB ... It is unclear how increases in bypass time would result in such increases if pre-existing cardiovascular and cerebrovascular ... Samuels MA (June 2006). "Can cognition survive heart surgery?". Circulation. 113 (24): 2784-6. doi:10.1161/CIRCULATIONAHA. ... Circulation. 113 (24): 2790-5. doi:10.1161/CIRCULATIONAHA.105.587931. PMID 16769915. Van Dijk D, Jansen E, Hijman R, Nierich A ...
https://en.wikipedia.org/wiki/Postperfusion_syndrome
Periodontal diseasePeriodontal disease
Wu T, Trevisan M, Genco RJ, Dorn JP, Falkner KL, Sempos CT (October 2000). "Periodontal disease and risk of cerebrovascular ... Circulation. 112 (1): 19-24. doi:10.1161/CIRCULATIONAHA.104.511998. PMID 15983248. Scannapieco FA, Bush RB, Paju S (December ... Circulation Journal. 79 (3): 495-502. doi:10.1253/circj.cj-15-0138. ISSN 1346-9843. PMC 4457364. PMID 25746525. Tsutsui, ... elevated levels of these inflammatory markers are also associated with cardiovascular disease and cerebrovascular events such ...
https://en.wikipedia.org/wiki/Periodontal_disease
Percutaneous aortic valve replacementPercutaneous aortic valve replacement
Ross, John; Braunwald, Eugene (1968). "Aortic Stenosis". Circulation. 38 (1s5): 61-7. doi:10.1161/01.cir.38.1s5.v-61. ISSN 0009 ... as well as in people with comorbidities such as cerebrovascular and peripheral arterial disease, chronic kidney disease, and ... First human case description". Circulation. 106 (24): 3006-3008. doi:10.1161/01.cir.0000047200.36165.b8. PMID 12473543. Buntz, ... leading to a higher circulation and kinetic energy, requiring the heart to work harder and consume more energy to maintain ...
https://en.wikipedia.org/wiki/Percutaneous_aortic_valve_replacement
List of skin conditionsList of skin conditions
ISBN 978-0-8493-3794-9. Ryan, T (1991). "Cutaneous Circulation". In Goldsmith, Lowell A (ed.). Physiology, biochemistry, and ... idiopathic livedo reticularis with cerebrovascular accidents) Solar purpura (actinic purpura, senile purpura) Stasis dermatitis ...
https://en.wikipedia.org/wiki/List_of_skin_conditions
Cerebral infarctionCerebral infarction
... partial anterior circulation infarct (PACI), lacunar infarct (LACI) or posterior circulation infarct (POCI). These four ... Cerebrovascular Diseases. 27 (5): 493-501. doi:10.1159/000210432. ISSN 1015-9770. PMID 19342825. Bamford J, Sandercock P, ... This is accomplished by inserting a catheter into the femoral artery, directing it into the cerebral circulation, and deploying ... Based on the extent of the symptoms, the stroke episode is classified as total anterior circulation infarct (TACI), ...
https://en.wikipedia.org/wiki/Cerebral_infarction
James I. AusmanJames I. Ausman
Slavin KV, Ausman JI, Charbel FT (1996). "Posterior circulation aneurysms other than basilar tip". In Tindall GT, Cooper PR, ... There he expanded his work in microsurgery, cerebrovascular surgery, particularly aneurysms, arteriovenous malformations and by ... Frequent topics of these articles have been: surgical aneurysm management brain circulation microanatomy, anastomosis and ...
https://en.wikipedia.org/wiki/James_I._Ausman
Glossary of diabetesGlossary of diabetes
Circulation the structures and control mechanisms which manage blood circulation. It includes the heart, lungs, arteries, veins ... Cerebrovascular disease damage to the blood vessels in the brain, resulting in a stroke - either ischemic (a blocked blood ... Artery Blood vessel with muscular walls on the 'supply side' of the blood circulation, in the network of vessels between the ... Diabetics often have edemic feet due to the impaired circulation in them. Electromyography EMG Test used to diagnose neuropathy ...
https://en.wikipedia.org/wiki/Glossary_of_diabetes
Hypertensive emergencyHypertensive emergency
In a hypertensive emergency, treatment should first be to stabilize the patient's airway, breathing, and circulation per ACLS ... Hypertensives also have an increased cerebrovascular resistance which puts them at greater risk of developing cerebral ischemia ...
https://en.wikipedia.org/wiki/Hypertensive_emergency
PorencephalyPorencephaly
With limited research, the most commonly regarded cause of porencephaly is disturbances in blood circulation, ultimately ... loss of blood outside of the circulatory system Brain contusion or injury Multifocal cerebrovascular insufficiency Placental ...
https://en.wikipedia.org/wiki/Porencephaly
Intracerebral hemorrhageIntracerebral hemorrhage
It accounts for 20% of all cases of cerebrovascular disease in the United States, behind cerebral thrombosis (40%) and cerebral ... January 2013). "Heart disease and stroke statistics-2013 update: a report from the American Heart Association". Circulation. ... which plays an important role in blood circulation and breathing. This kind of hemorrhage can also occur in the cortex or ... Cerebrovascular diseases, Neurotrauma, Wikipedia medicine articles ready to translate, Wikipedia neurology articles ready to ...
https://en.wikipedia.org/wiki/Intracerebral_hemorrhage
List of medical mnemonicsList of medical mnemonics
ABC - airway, breathing, and circulation AEIOU-TIPS - causes of altered mental status APGAR - a backronym for appearance, pulse ... coronary/cerebrovascular/peripheral artery disease Eye - cataracts, retinopathy Skin - lipohypertrophy/lipoatrophy, necrobiosis ...
https://en.wikipedia.org/wiki/List_of_medical_mnemonics
Vertebral artery dissectionVertebral artery dissection
Fisher CM (November 2001). "A career in cerebrovascular disease: a personal account". Stroke. 32 (11): 2719-2724. doi:10.1161/ ... and this type of stroke is therefore called a posterior circulation infarct. Problems may include difficulty speaking or ...
https://en.wikipedia.org/wiki/Vertebral_artery_dissection
RofecoxibRofecoxib
Patrono, Carlo; Baigent, Colin (2014-02-25). "Nonsteroidal Anti-Inflammatory Drugs and the Heart". Circulation. 129 (8): 907- ... cerebrovascular accident, transient ischemic attack, or coronary artery bypass). Merck's scientists interpreted the finding as ... Circulation. 104 (19): 2280-2288. doi:10.1161/hc4401.100078. PMID 11696466. Bresalier RS, Sandler RS, Quan H, Bolognese JA, ... summarizing all of the currently available data in a review article in Circulation, concluded that with the exception of GI ...
https://en.wikipedia.org/wiki/Rofecoxib
Complications of hypertensionComplications of hypertension
The retinal circulation undergoes a series of pathophysiological changes in response to elevated blood pressure. In the initial ... Pantoni L, Poggesi A, Inzitari D (2009). "Cognitive decline and dementia related to cerebrovascular diseases: some evidence and ... Varon J (October 2007). "Diagnosis and management of labile blood pressure during acute cerebrovascular accidents and other ... loss of libido and poor circulation of blood in the legs. When the blood supply to the feet is compromised, the chances of ...
https://en.wikipedia.org/wiki/Complications_of_hypertension
SeizureSeizure
In older adults, cerebrovascular disease is a very common cause. Other causes are CNS tumors, head trauma, and other ... and circulation. Airway management should include placing the person on their side, known as the recovery position, to prevent ...
https://en.wikipedia.org/wiki/Seizure
CigarCigar
... cerebrovascular diseases, periodontal diseases and teeth loss, and malignant diseases. The word cigar originally derives from ... Circulation, Resistance, and Diversity. Basingstoke: Palgrave Macmillan. pp. 216-229. doi:10.1057/9781137324054_12. ISBN 978-1- ...
https://en.wikipedia.org/wiki/Cigar
Al CaponeAl Capone
The protagonists of Chicago's politics had long been associated with questionable methods, and even newspaper circulation "wars ... Deaths from cerebrovascular disease, Depression-era gangsters, Deaths from syphilis, Five Points Gang, Inmates of Alcatraz ...
https://en.wikipedia.org/wiki/Al_Capone
Amaurosis fugaxAmaurosis fugax
Newman NJ (1998). "Cerebrovascular disease". In Hoyt WG, Miller N, Walsh F, Newman NJ (eds.). Walsh and Hoyt's Clinical Neuro- ... leading to a decrease in retinal circulation which, in turn, causes retinal hypoxia. While, most commonly, emboli causing ... bright light may indicate ipsilateral carotid artery occlusive disease and may reflect the inability of borderline circulation ...
https://en.wikipedia.org/wiki/Amaurosis_fugax
John Pickard (neurosurgeon)John Pickard (neurosurgeon)
Pickard, JD; Mackenzie, ET (1973). "Inhibition of prostaglandin synthesis and the response of baboon cerebral circulation to ... "Continuous monitoring of cerebrovascular pressure reactivity allows determination of optimal cerebral perfusion pressure in ... The Role of Prostaglandins in the Control of the Cerebral Circulation') from the University of Cambridge in 1981. He is a ...
https://en.wikipedia.org/wiki/John_Pickard_(neurosurgeon)
Altered cerebrovascular response pattern in interictal migraine during visual stimulationAltered cerebrovascular response pattern in interictal migraine during visual stimulation
To determine the dynamic pattern of the cerebrovascular response in migraineurs compared with a control group, changes of the ... A dysbalance of the cerebrovascular response during functional activation of the brain has been postulated as a factor in the ... Altered cerebrovascular response pattern in interictal migraine during visual stimulation Cephalalgia. 2001 Jun;21(5):611-6. ... A dysbalance of the cerebrovascular response during functional activation of the brain has been postulated as a factor in the ...
https://pubmed.ncbi.nlm.nih.gov/11472388/
Vertebral Artery Dissection Workup: Laboratory Studies, CT Scanning, MRI, and MRA, Four-Vessel Cerebral AngiographyVertebral Artery Dissection Workup: Laboratory Studies, CT Scanning, MRI, and MRA, Four-Vessel Cerebral Angiography
Erythrocyte sedimentation rate (ESR), if elevated, may suggest vasculitis involving the cerebrovascular circulation. ... HITS are associated with symptomatic ischemic symptoms both in VAD and in other types of cerebrovascular disease. ... Urgent off-label use of the pipeline flow diverter stent in selected ischemic cerebrovascular conditions: thrombotic segments ...
https://www.medscape.com/answers/761451-111134/what-is-the-role-of-duplex-ultrasonography-in-the-workup-of-vertebral-artery-dissection-vad
Pediatric Patent Foramen Ovale Atrial Septal Defects: Background, Pathophysiology, EpidemiologyPediatric Patent Foramen Ovale Atrial Septal Defects: Background, Pathophysiology, Epidemiology
Recurrent cerebrovascular events associated with patent foramen ovale, atrial septal aneurysm, or both. N Engl J Med. 2001 Dec ... The foramen ovale is essential for proper fetal circulation, directing oxygenated, nutrient-rich blood from the placenta, ... Population-based study of the relationship between patent foramen ovale and cerebrovascular ischemic events. Mayo Clin Proc. ... Secondary prevention after cryptogenic cerebrovascular events in patients with patent foramen ovale. Int J Cardiol. 2005 May 11 ...
https://emedicine.medscape.com/article/894483-overview
Blood, Heart and Circulation: MedlinePlusBlood, Heart and Circulation: MedlinePlus
Cerebrovascular Disease see Stroke * Chest Pain * CHF see Heart Failure * Childhood Leukemia ...
https://medlineplus.gov/bloodheartandcirculation.html
Metabolic and functional correlates of age-related hearing loss: advanced MRI findings and rehabilitation perspectives of the...
KEY WORDS: Hearing loss; Presbycusis; Cerebrovascular circulation; Magnetic resonance imaging. top of page ...
https://www.minervamedica.it/en/journals/Otorhinolaryngology/article.php?cod=R27Y2021N03A0125
Sharon Abrahams - Research output - University of Edinburgh Research Explorer
Cerebrovascular Circulation 45% * The validation of the Italian Edinburgh Cognitive and Behavioural ALS Screen (ECAS). Poletti ...
https://www.research.ed.ac.uk/en/persons/sharon-abrahams/publications/?ordering=title&descending=false&page=3
Earnest Richard Dick Greene - New Mexico Highlands UniversityEarnest Richard "Dick" Greene - New Mexico Highlands University
Hayward W, Fritz K, Montano J, Greene ER, Dynamic responses of the human cerebrovascular circulation during sexual intercourse ... Dynamic response of the human cerebrovascular circulation to the onset of exercise. FASEB, 1997; 11(3): A474. ... Circulation 1982;66:II‑319.. *Voyles WF, Greene ER, Eldridge M. In vitro comparison of fast Fourier trans-form (FFT) and zero‑ ... Circulation 1980;62(4 Pt 2):III‑48.. *Richards K, Crawford M, Cannon S, Greene ER, Hoekenga D, ORourke R. Quantific-ation of ...
https://www.nmhu.edu/our-faculty/dick-greene/
Toward a further elucidation: role of vertebral artery hypoplasia in acute ischemic strokeToward a further elucidation: role of vertebral artery hypoplasia in acute ischemic stroke
Background and purpose: Congenital vertebral artery (VA) hypoplasia is an uncommon embryonic variation of posterior circulation ... subtype and a topographic preponderance of ipsilateral posterior circulation infarction. ... Cerebrovascular Circulation / physiology* * Congenital Abnormalities / epidemiology * Female * Humans * Incidence * Male * ...
https://pubmed.ncbi.nlm.nih.gov/16772715/?dopt=Abstract
Cerebral effects of low-flow cardiopulmonary bypass and hypothermic circulatory arrest<...
Cerebrovascular Circulation Medicine & Life Sciences 10% * Nervous System Medicine & Life Sciences 9% ... Cerebrovascular resistance rose slightly in the low-flow CPB group postoperatively in contrast to a marked elevation in the HCA ... Cerebrovascular resistance rose slightly in the low-flow CPB group postoperatively in contrast to a marked elevation in the HCA ... Cerebrovascular resistance rose slightly in the low-flow CPB group postoperatively in contrast to a marked elevation in the HCA ...
https://jhu.pure.elsevier.com/en/publications/cerebral-effects-of-low-flow-cardiopulmonary-bypass-and-hypotherm-5
Study of cognition activated regional cerebral blood flow diversity in mild depression<...
Cerebrovascular Circulation Medicine & Life Sciences 85% * Cognition Medicine & Life Sciences 69% * Single-Photon Emission- ...
https://asu.pure.elsevier.com/en/publications/study-of-cognition-activated-regional-cerebral-blood-flow-diversi
Total dependence of the cerebral circulation on the right vertebral artery in Takayasus disease-A case report<...Total dependence of the cerebral circulation on the right vertebral artery in Takayasu's disease-A case report<...
Cerebrovascular Circulation Medicine & Life Sciences 82% * Takayasu Arteritis Medicine & Life Sciences 75% ... Elewaut, DS, Duprez, DA, De Buyzere, ML, Kunnen, MF & Clement, DL 1994, Total dependence of the cerebral circulation on the ... Total dependence of the cerebral circulation on the right vertebral artery in Takayasus disease-A case report. / Elewaut, D. S ... Total dependence of the cerebral circulation on the right vertebral artery in Takayasus disease-A case report. International ...
https://experts.umn.edu/en/publications/total-dependence-of-the-cerebral-circulation-on-the-right-vertebr-2
Neurology - Research output - Mayo Clinic
Professor Itsu Sen (Yi Qian) - Macquarie UniversityProfessor Itsu Sen (Yi Qian) - Macquarie University
... are equipped with mock circulation systems with cardiovascular modelling technology to perform simulations of cerebrovascular ... He also has developed novel methodologies based on the CFD techniques for improvement cardiovascular and cerebrovascular ... in order to perform patient-specific cerebrovascular blood simulation. Research projects are to be aimed at assisting vascular ... cardiovascular and cerebrovascular stents, artery graft R&D, and medical image software development etc. ...
https://www.mq.edu.au/about_us/faculties_and_departments/faculty_of_medicine_and_health_sciences/research/research_groups/our_staff/professor_itsu_sen
Neonatal cerebrovascular autoregulation.
Cerebrovascular Circulation, Infant, Infant, Newborn, Arterial Pressure ... Rhee, C. J., da Costa, C. S., Austin, T., Brady, K. M., Czosnyka, M., & Lee, J. K. (2018). Neonatal cerebrovascular ... Cerebrovascular pressure autoregulation is the physiologic mechanism that holds cerebral blood flow (CBF) relatively constant ...
https://www.repository.cam.ac.uk/handle/1810/287047
New Cardiopulmonary Resuscitation Guidelines 2005: Importance of Uninterrupted Chest Compression<...
Cerebrovascular Circulation Medicine & Life Sciences 17% * Resuscitation Medicine & Life Sciences 17% View full fingerprint ...
https://moh-it.pure.elsevier.com/en/publications/new-cardiopulmonary-resuscitation-guidelines-2005-importance-of-u
Åkeson, J.<...Åkeson, J.<...
Cerebrovascular Circulation Medicine & Life Sciences 88% * Ketamine Medicine & Life Sciences 87% * Swine Medicine & Life ...
https://portal.research.lu.se/en/persons/jonas-%C3%A5keson
Pediatric Patent Foramen Ovale Atrial Septal Defects Treatment & Management: Approach Considerations, Medical Care, Surgical...Pediatric Patent Foramen Ovale Atrial Septal Defects Treatment & Management: Approach Considerations, Medical Care, Surgical...
Recurrent cerebrovascular events associated with patent foramen ovale, atrial septal aneurysm, or both. N Engl J Med. 2001 Dec ... Circulation. 2002 Jun 4. 105(22):2625-31. [QxMD MEDLINE Link]. [Full Text]. ... Population-based study of the relationship between patent foramen ovale and cerebrovascular ischemic events. Mayo Clin Proc. ... Secondary prevention after cryptogenic cerebrovascular events in patients with patent foramen ovale. Int J Cardiol. 2005 May 11 ...
https://emedicine.medscape.com/article/894483-treatment
Visualization and molecular characterization of whole-brain vascular networks with capillary resolution | Nature CommunicationsVisualization and molecular characterization of whole-brain vascular networks with capillary resolution | Nature Communications
Structural and molecular elucidation of cerebrovascular network is promising for understanding energy supply system in the ... analyses of cerebral vasculature are promising for providing fundamental insights into cerebral circulation and cerebrovascular ... 5h-j, Supplementary Movies 5, 6). These bypasses may actively exchange arterial blood and serve as a backup circulation pathway ... Walker, E. J., Shen, F., Young, W. L. & Su, H. Cerebrovascular casting of the adult mouse for 3D imaging and morphological ...
https://www.nature.com/articles/s41467-020-14786-z?error=cookies_not_supported&code=63690d46-8b9d-4f66-81c5-3d205deb2e8d
MH DELETED MN ADDED MNMH DELETED MN ADDED MN
G7.345.500.550.500.500.150 Cerebrovascular Circulation G9.330.190.163.159 G9.330.100.159 Cervical Rib A2.835.232.904.567.150 ... Renal Circulation G8.852.796.700 G8.852.725 G9.330.190.163.812 G9.330.100.812 Renal Colic G11.561.600.810.444.850 G11.561. ... Blood Circulation G9.330.190.163 G9.330.100 Blood Coagulation G9.188.124.560.150 G9.188.390.150 Blood Physiological Processes ... Collateral Circulation G9.330.190.163.248 G9.330.100.248 Colles Fracture C5.116.359.336.500 C26.289.336.500 Colony Collapse ...
https://decs.bvs.br/E/mnchg2017.txt
Publications | The Douglas Research CentrePublications | The Douglas Research Centre
Filters: Keyword is Cerebrovascular Circulation and Author is Lecrux, Clotilde [Clear All Filters] ...
https://douglas.research.mcgill.ca/publications?f%5Bkeyword%5D=3450&f%5Bauthor%5D=4494&s=author&o=asc
Bauer E. Sumpio, MD, PhD Vascular Surgery | Yale New Haven HospitalBauer E. Sumpio, MD, PhD Vascular Surgery | Yale New Haven Hospital
Cerebrovascular Disease, Circulation Problems, Congenital Malformations & Deformit, Deep Vein Thrombosis (DVT), Diabetic Foot ...
https://www.ynhh.org/physicians/bauer-e-sumpio
David B. Falk College of Sport & Human Dynamics - Research output - [email protected]
Costa, M. R., Bergen-Cico, D., Grant, T., Herrero, R., Navarro, J., Razza, R. & Wang, Q., 2019, Augmented Cognition - 13th International Conference, AC 2019, Held as Part of the 21st HCI International Conference, HCII 2019, Proceedings. Schmorrow, D. D. & Fidopiastis, C. M. (eds.). Springer Verlag, p. 517-532 16 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 11580 LNAI).. Research output: Chapter in Book/Report/Conference proceeding › Conference contribution ...
https://experts.syr.edu/en/organisations/david-b-falk-college-of-sport-human-dynamics/publications/?page=12
Hua-Shan Liu - 研究成果 - 臺北醫學大學
Elsar 25mg Tablet 10S - Buy Medicines online at Best Price from Netmeds.comElsar 25mg Tablet 10'S - Buy Medicines online at Best Price from Netmeds.com
suffer from cerebrovascular disease (caused by a reduced blood circulation to the brain) ...
https://www.netmeds.com/prescriptions/elsar-25mg-tablet-10-s
Albert Einstein College of Medicine - Grants - Albert Einstein College of MedicineAlbert Einstein College of Medicine - Grants - Albert Einstein College of Medicine
Cerebrovascular Circulation 40% * Training in Aging Research. Barzilai, N., Rossetti, L., Rose, S. A., Rose, S. A. & Rose, S. A ...
https://einstein.pure.elsevier.com/en/organisations/albert-einstein-college-of-medicine/projects/?status=FINISHED&ordering=statusStartDate&descending=true&page=53
Improving Collateral Circulation | NDTImproving Collateral Circulation | NDT
Compensatory characteristics of diff levels of cerebral collateral circulation, collateral circulation & VaD relationship, & ... Cerebrovascular disease and dementia. Br J Radiol. 2007;80 Spec No 2:S121-127. doi:10.1259/bjr/75681080 ... Relevance of the Collateral Circulation to VaD. Collateral Circulation and Atherosclerosis. Different from a single disease, ... Different Levels of Collateral Circulation and Its Compensation Characteristics. Collateral circulation in the brain is usually ...
https://www.dovepress.com/improving-collateral-circulation-a-potential-adjunctive-strategy-to-pr-peer-reviewed-fulltext-article-NDT
Search ResultsSearch Results
Cerebrovascular Circulation - Dr... (1) Cardiovascular System & Card... (1) Cardiac And Cardiovascular Systems (1) Brain - ... Cerebrovascular Diseases Subjects. Brain Ischemia - Physiopathology (1) Brain Ischemia - Pathology (1) Brain Ischemia - ... jtitle:Cerebrovascular Diseases. topic:Brain - Blood Supply. topic:Anti-Inflammatory Agents - Pharmacology. topic: ...
https://beluga.sub.uni-hamburg.de/vufind/Primo/Search?lookfor=+Schwab%2C+U+&type=Author&filter%5B%5D=rtype%3A%22Articles%22&filter%5B%5D=jtitle%3A%22Cerebrovascular+Diseases%22&filter%5B%5D=topic%3A%22Brain+-+Blood+Supply%22&filter%5B%5D=topic%3A%22Anti-Inflammatory+Agents+-+Pharmacology%22&filter%5B%5D=topic%3A%22Biomedical+Research%22&filter%5B%5D=topic%3A%22Brain+Ischaemia%22&dfApplied=1
Cardiovascular and cerebrovascularStrokeHumansDiseasesArterialAtherosclerosisEndothelial CellsDiseaseCerebral blooJournal of cerebral circulationHypercapniaVascularPatientsOcclusiveBrainPosterior circulationPerfusionDisturbanceAutoregulationGlucoseDisordersPulmonary circulationArteriesIntracranialSpinalCollateralResearchMiceOxygen
Cardiovascular and cerebrovascular4
  • He also has developed novel methodologies based on the CFD techniques for improvement cardiovascular and cerebrovascular surgical method, and estimation the risk of cerebral aneurysms. (edu.au)
  • e.g. artificial heart, cardiovascular and cerebrovascular stents, artery graft R&D, and medical image software development etc. (edu.au)
  • Alpha-adducin polymorphism, atherosclerosis, and cardiovascular and cerebrovascular risk. (cdc.gov)
  • 3-Hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors (statins) effectively reduce cholesterol levels and decrease the incidence of cardiovascular and cerebrovascular events (4). (cdc.gov)
Stroke9
  • Based on our results, VA hypoplasia seemed a contributing factor of acute ischemic stroke, especially in posterior circulation territories. (nih.gov)
  • Journal of Stroke and Cerebrovascular Diseases. (elsevier.com)
  • 2 Cardiovascular diseases include all the diseases of the heart and circulation such as coronary heart disease, angina, heart attacks and stroke (cerebrovascular disease). (who.int)
  • At present, considerable effort has been devoted to enhancing the functional prognosis of acute ischemic stroke by improving collateral circulation. (dovepress.com)
  • Since ischemic stroke is the primary contributor to VaD, it is necessary to explore whether improving collateral circulation is beneficial to prevent or slow the progression of VaD. (dovepress.com)
  • He did his clinical internship in the cerebrovascular laboratories at Harborview Medical Center and Spencer Vascular Diagnostic Services in Seattle, institutions with internationally renowned Doppler ultrasonography and stroke prevention programs. (barrowneuro.org)
  • Cerebrovascular disease, stroke or cerebrovascular accident, is a vascular disease of the cerebral circulation. (icd.codes)
  • Microglial-mediated PDGF-CC activation increases cerebrovascular permeability during ischemic stroke. (shefayekhatam.ir)
  • Do you have any problems with your heart or circulation including heart attacks, angina (chest pain), heart failure, a stroke or mini stroke, or claudication (cramping pain in yours legs when you walk)? (pharmacyplanet.com)
Humans1
  • Further understanding of disease mechanisms and therapeutic strategies requires a deeper knowledge of cerebrovascular cells in humans. (bvsalud.org)
Diseases3
  • Collateral circulation, a compensation mechanism for CBF, provides an alternative vascular pathway for blood to reach ischemic tissues, which has been confirmed to be associated with better clinical outcomes of ischemic diseases. (dovepress.com)
  • Arteries supplying oxygen to the brain are affected resulting in one of a number of cerebrovascular diseases. (icd.codes)
  • Cerebrovascular diseases are a leading cause of death and neurologic disability. (bvsalud.org)
Arterial3
  • The progression of the disease in the absence of inflammatory episodes since 1988 and the total dependence of the cerebral arterial circulation on the right vertebral artery are the hallmarks of this very rare case of Takayasu's disease. (umn.edu)
  • Mr. Foster has participated in multiple national and international research studies in cerebrovascular stenting, peripheral arterial stenting, migraines, patent foramen ovale, and sickle cell disease. (barrowneuro.org)
  • People with diabetes are also at increased risk of cardiac, peripheral arterial and cerebrovascular disease ( 3 ). (bvs.br)
Atherosclerosis3
  • Of these, subjects with VA hypoplasia had an etiological preponderance of the 'large-artery atherosclerosis' subtype and a topographic preponderance of ipsilateral posterior circulation infarction. (nih.gov)
  • Cerebrovascular disease is the most common life-threatening neurological event in the U.S. Intracranial atherosclerosis is responsible for approximately 40,000 of these attacks per year, representing 10 percent of all ischemic strokes. (aans.org)
  • Association of the glutathione S-transferase omega-1 Ala140Asp polymorphism with cerebrovascular atherosclerosis and plaque-associated interleukin-1 alpha expression. (cdc.gov)
Endothelial Cells1
  • However, cultured mouse cerebrovascular endothelial cells treated with serum from MWCNT-exposed mice pretreated with MMP blockade exhibited approx. (cdc.gov)
Disease10
  • Vascular dementia (VaD), a cognitive disorder caused by cerebrovascular pathologies, is the most common cause of dementia in the elderly, being second only to Alzheimer's disease. (dovepress.com)
  • Evaluation of the intracranial circulation is an essential component of the angiographic study of occlusive extracranial cerebrovascular disease. (ajnr.org)
  • This article is based on our clinical experience, European guidelines for acute cerebrovascular disease and recent medical literature found by searching Medline. (tidsskriftet.no)
  • The term cerebrovascular disease includes all disorders in which an area of the brain is temporarily or permanently affected by ischemia or bleeding and one or more of the cerebral blood vessels are involved in the pathological process. (aans.org)
  • Results: Cerebrovascular response to hypercapnia severely decreased over the cerebral cortices in both pediatric and adult patients with moyamoya disease when compared with those of normal control subjects, and there was no significant difference between pediatric and adult patients. (elsevier.com)
  • CTA is of increasing value in identifying occlusive disease in the cerebrovascular circulation. (medscape.com)
  • The disease is associated with early-onset relapsing immune-mediated inflammatory axonal or demyelinating sensory-motor peripheral polyneuropathy and isolated or recurrent cerebrovascular events (in anterior or posterior circulation). (cdc.gov)
  • Complex Profiles of Cerebrovascular Disease Pathologies in the Aging Brain and Their Relationship With Cognitive Decline. (rush.edu)
  • CVD outcomes included death and hospitalisations for ischaemic heart disease, heart failure, cerebrovascular disease, peripheral artery disease or aortic aneurysm. (bmj.com)
  • Cerebrovascular disease- This health disorder can interfere with the blood flow to the brain can cause difficulty in performing tasks, including sexual intercourse. (alldaychemist.com)
Cerebral bloo3
  • Cerebrovascular pressure autoregulation is the physiologic mechanism that holds cerebral blood flow (CBF) relatively constant across changes in cerebral perfusion pressure (CPP). (cam.ac.uk)
  • This study investigated basal cerebral blood flow and cerebrovascular reactivity in wild-type mice, diabetic mice (Ins2 Akita +/- ), nondiabetic eNOS-overexpressing mice (TgeNOS), and the cross of two transgenic mice (TgeNOS-Ins2 Akita +/- ) at six months of age. (elsevier.com)
  • Cerebrovascular CO 2 response was estimated as the percentage change of cerebral blood flow per 1 mm Hg change of PaCO2. (elsevier.com)
Journal of cerebral circulation2
  • a journal of cerebral circulation 2006 Dec 37 (12): 2930-4. (cdc.gov)
  • a journal of cerebral circulation 2007 Oct 38 (10): 2847-50. (cdc.gov)
Hypercapnia1
  • In this study, we measured the cerebrovascular response to hypercapnia using 1 5 O H 2 O positron emission tomography (PET) in each group of patients. (elsevier.com)
Vascular5
  • Research projects are to be aimed at assisting vascular surgeons in the management, treatment, and risk estimation of cerebrovascular aneurysms. (edu.au)
  • Mr. Foster's expertise includes vascular testing, with an emphasis on cerebrovascular circulation. (barrowneuro.org)
  • The word cerebrovascular is made up of two parts - "cerebro" which refers to the large part of the brain, and "vascular" which means arteries and veins. (aans.org)
  • While elevated intraocular pressure (IOP) is a clear risk factor, vascular insufficiency and abnormal autoregulation of the optic nerve circulation have been hypothesised to play a significant role in the development and progression of glaucoma. (bmj.com)
  • Pacientes que presentaron Fuerzas de cillazamiento, Historia de accidente vascular encefálico, Inmovilización física, alteración en la función cognitiva y alteración en la sensibilidad presentaron puntajes más bajos en la Escala de Braden. (bvsalud.org)
Patients2
  • The aim of this study was to determine the preferential scheme of medical therapy in perioperative management of cardiac surgery patients with extracorporeal circulation, with IHD or with chronic heart insufficiency (CHI) from the point of view of pharmacoeconomic analysis by comparing ratios between expenses and efficacy, safety and quality of life associated with the use of Neoton (phosphocreatine) in comparison with the control group. (pharmacoeconom.com)
  • Results of the budget impact analysis have shown that the use of the standard therapy + phosphocreatine instead of the standard therapy itself in perioperative management of cardiac surgery patients with extracorporeal circulation, with IHD or with CHI has saved money. (pharmacoeconom.com)
Occlusive1
  • Selective catheter placement optimally shows the extracranial and intracranial circulation and better defines occlusive morphology, tandem occlusive lesions, and coincident or contributory pathology. (ajnr.org)
Brain5
  • A dysbalance of the cerebrovascular response during functional activation of the brain has been postulated as a factor in the pathophysiology of migraine. (nih.gov)
  • It is assumed that a lack of habituation of the cerebrovascular response in migraineurs might contribute to a disturbance of the metabolic homeostasis of the brain that might induce migraine attacks. (nih.gov)
  • The foramen ovale is essential for proper fetal circulation, directing oxygenated, nutrient-rich blood from the placenta, preferentially to the developing fetal brain. (medscape.com)
  • The circulation of blood through the BLOOD VESSELS of the BRAIN . (bvsalud.org)
  • Together, the word cerebrovascular refers to blood flow in the brain. (aans.org)
Posterior circulation1
  • Congenital vertebral artery (VA) hypoplasia is an uncommon embryonic variation of posterior circulation. (nih.gov)
Perfusion1
  • To determine the dynamic pattern of the cerebrovascular response in migraineurs compared with a control group, changes of the cerebral perfusion during cerebral activation were studied with high temporal resolution by functional transcranial Doppler sonography (fTCD). (nih.gov)
Disturbance1
  • New areas of neurosurgery were developed: further study of the etiology and pathogenesis of acute cerebrovascular disturbance, diagnostics and surgical treatment of cerebral hemorrhagic strokes (G.P.Pedachenko, L.Ye.Pelekh, O.P.Burlutskyi), study of the pathogenesis and treatment of spinal cord compression, study of the dynamics epileptogenic foci and epilepsy surgery, stereotactic surgery for extrapyramidal hyperkinesia. (kiev.ua)
Autoregulation1
  • Neonatal cerebrovascular autoregulation. (cam.ac.uk)
Glucose2
  • measurement of glucose consumption, and determination of cerebrovascular resistance. (elsevier.com)
  • These data suggest that after HCA there is a vulnerable interval, lasting as late as 8 hours postoperatively, in which cerebrovascular resistance remains high and cerebral metabolism is maintained primarily by high oxygen and glucose extraction. (elsevier.com)
Disorders1
  • It can also help manage dizziness of vestibular/cerebrovascular origin, and peripheral circulation disorders caused by organic arteriopathies. (buy-pharma.md)
Pulmonary circulation1
  • The shunt leads to a state where the right side of heart and the pulmonary circulation suffers a volume and pressure increase which can be suspected on chest radiographs. (bme.hu)
Arteries1
  • the project is to investigate pathophysiology of intracranial aneurysms, an abnormal bulging of cerebral arteries, specifically investigate various cellular and molecular basis which make cerebral arteries prone to mechanical weakness, leading to initiation and progression of aneurysms using animal models, and t o evaluate the association between cerebrovascular remodeling, hemodynamic factors and biomarkers. (edu.au)
Intracranial1
  • Neuroangiography is a process by which the intracranial and extracranial head and neck circulation is evaluated. (ajnr.org)
Spinal1
  • To determine the effect of the 5-HT2A receptor in control of spinal nociception, cerebral circulation, and nitric oxide synthase (nNOS) expression in trigeminovascular neurons. (swu.ac.th)
Collateral2
  • This article reviews the compensatory characteristics of different levels of cerebral collateral circulation, addresses the relationship between collateral circulation and VaD, and highlights that improving collateral circulation may be a potential adjunctive strategy in preventing and slowing the progression of VaD. (dovepress.com)
  • Transcranial Doppler can be a complementary examination evaluating the patency of cerebral vessels and collateral circulation. (medscape.com)
Research1
Mice1
  • iii) The cerebrovascular reactivity in the Ins2 Akita +/- mice was significantly lower compared with wild-type, whereas that in the TgeNOS-Ins2 Akita +/- was significantly higher compared with the Ins2 Akita +/- and TgeNOS groups. (elsevier.com)
Oxygen2
  • During the period of high cerebrovascular resistance after HCA, cerebral metabolic rate of oxygen was maintained by increased oxygen extraction. (elsevier.com)
  • After low-flow CPB, oxygen extraction was not significantly different from baseline, presumably because of less severe changes in cerebrovascular resistance. (elsevier.com)
Pediatric Patent Foramen Ovale Atrial Septal Defects: Background, Pathophysiology, Epidemiology
Pediatric Patent Foramen Ovale Atrial Septal Defects: Background, Pathophysiology, Epidemiology (emedicine.medscape.com)
Vertebral Artery Dissection Workup: Laboratory Studies, CT Scanning, MRI, and MRA, Four-Vessel Cerebral Angiography
Vertebral Artery Dissection Workup: Laboratory Studies, CT Scanning, MRI, and MRA, Four-Vessel Cerebral Angiography (medscape.com)
Blood, Heart and Circulation: MedlinePlus
Blood, Heart and Circulation: MedlinePlus (medlineplus.gov)
First In Utero Cerebrovascular Surgery Success
First In Utero Cerebrovascular Surgery Success (medscape.com)
Tobacco Control Interventions | Health Impact in 5 Years | Health System Transformation | AD for Policy | CDC
Tobacco Control Interventions | Health Impact in 5 Years | Health System Transformation | AD for Policy | CDC (cdc.gov)
Prevención de ataque cardíaco y accidente cerebrovascular por diabetes: MedlinePlus enciclopedia médica
Prevención de ataque cardíaco y accidente cerebrovascular por diabetes: MedlinePlus enciclopedia médica (medlineplus.gov)
The Burden of Cerebrovascular Disease in the United States
The Burden of Cerebrovascular Disease in the United States (cdc.gov)
Sharon Abrahams - Research output - University of Edinburgh Research Explorer
Sharon Abrahams - Research output - University of Edinburgh Research Explorer (research.ed.ac.uk)
Racial Disparities in Asthma Hospitalizations Following Implementation of the Smoke-Free Air Law, Michigan, 2002-2012
Racial Disparities in Asthma Hospitalizations Following Implementation of the Smoke-Free Air Law, Michigan, 2002-2012 (cdc.gov)
Study of cognition activated regional cerebral blood flow diversity in mild depression<...
Study of cognition activated regional cerebral blood flow diversity in mild depression<... (asu.pure.elsevier.com)
Neurology - Research output - Mayo Clinic
Neurology - Research output - Mayo Clinic (mayoclinic.pure.elsevier.com)
Professor Itsu Sen (Yi Qian) - Macquarie University
Professor Itsu Sen (Yi Qian) - Macquarie University (mq.edu.au)
Spinal Cord Infarction Follow-up: Further Outpatient Care, Further Inpatient Care, Inpatient & Outpatient Medications
Spinal Cord Infarction Follow-up: Further Outpatient Care, Further Inpatient Care, Inpatient & Outpatient Medications (medscape.com)
Pediatric Patent Foramen Ovale Atrial Septal Defects Workup: Laboratory Studies, Imaging Studies
Pediatric Patent Foramen Ovale Atrial Septal Defects Workup: Laboratory Studies, Imaging Studies (emedicine.medscape.com)
NLMID: 101743402X27 - Louis Sokoloff - Profiles in Science Search Results
NLMID: 101743402X27 - Louis Sokoloff - Profiles in Science Search Results (profiles.nlm.nih.gov)
Creator: Jehle, Jane - Louis Sokoloff - Profiles in Science Search Results
Creator: Jehle, Jane - Louis Sokoloff - Profiles in Science Search Results (profiles.nlm.nih.gov)
NLMID: 101743402X36 - Louis Sokoloff - Profiles in Science Search Results
NLMID: 101743402X36 - Louis Sokoloff - Profiles in Science Search Results (profiles.nlm.nih.gov)
NLMID: 101743402X39 - Louis Sokoloff - Profiles in Science Search Results
NLMID: 101743402X39 - Louis Sokoloff - Profiles in Science Search Results (profiles.nlm.nih.gov)
Creator: Mangold, Renward - Louis Sokoloff - Profiles in Science Search Results
Creator: Mangold, Renward - Louis Sokoloff - Profiles in Science Search Results (profiles.nlm.nih.gov)
NLMID: 101743402X29 - Louis Sokoloff - Profiles in Science Search Results
NLMID: 101743402X29 - Louis Sokoloff - Profiles in Science Search Results (profiles.nlm.nih.gov)
Louis Sokoloff - Profiles in Science Search Results
Louis Sokoloff - Profiles in Science Search Results (profiles.nlm.nih.gov)
Publisher: American Society for Clinical Investigation - Louis Sokoloff - Profiles in Science Search Results
Publisher: American Society for Clinical Investigation - Louis Sokoloff - Profiles in Science Search Results (profiles.nlm.nih.gov)
NLMID: 101743402X63 - Louis Sokoloff - Profiles in Science Search Results
NLMID: 101743402X63 - Louis Sokoloff - Profiles in Science Search Results (profiles.nlm.nih.gov)
Creator: King, Benton D. - Louis Sokoloff - Profiles in Science Search Results
Creator: King, Benton D. - Louis Sokoloff - Profiles in Science Search Results (profiles.nlm.nih.gov)