An irregularly shaped cavity in the RHOMBENCEPHALON, located between the MEDULLA OBLONGATA; the PONS; and the isthmus in front, and the CEREBELLUM behind. It is continuous with the central canal of the cord below and with the CEREBRAL AQUEDUCT above, and through its lateral and median apertures it communicates with the SUBARACHNOID SPACE.
Cavity in each of the CEREBRAL HEMISPHERES derived from the cavity of the embryonic NEURAL TUBE. They are separated from each other by the SEPTUM PELLUCIDUM, and each communicates with the THIRD VENTRICLE by the foramen of Monro, through which also the choroid plexuses (CHOROID PLEXUS) of the lateral ventricles become continuous with that of the third ventricle.
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
The formation of an area of NECROSIS in the CEREBRUM caused by an insufficiency of arterial or venous blood flow. Infarcts of the cerebrum are generally classified by hemisphere (i.e., left vs. right), lobe (e.g., frontal lobe infarction), arterial distribution (e.g., INFARCTION, ANTERIOR CEREBRAL ARTERY), and etiology (e.g., embolic infarction).
Body Temperature Regulation
Cerebral Ventricle Neoplasms
Neoplasms located in the brain ventricles, including the two lateral, the third, and the fourth ventricle. Ventricular tumors may be primary (e.g., CHOROID PLEXUS NEOPLASMS and GLIOMA, SUBEPENDYMAL), metastasize from distant organs, or occur as extensions of locally invasive tumors from adjacent brain structures.
A propylamine formed from the cyclization of the side chain of amphetamine. This monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and phobic disorders. (From AMA Drug Evaluations Annual, 1994, p311)
The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)
A narrow cleft inferior to the CORPUS CALLOSUM, within the DIENCEPHALON, between the paired thalami. Its floor is formed by the HYPOTHALAMUS, its anterior wall by the lamina terminalis, and its roof by EPENDYMA. It communicates with the FOURTH VENTRICLE by the CEREBRAL AQUEDUCT, and with the LATERAL VENTRICLES by the interventricular foramina.
A heterogeneous group of nonprogressive motor disorders caused by chronic brain injuries that originate in the prenatal period, perinatal period, or first few years of life. The four major subtypes are spastic, athetoid, ataxic, and mixed cerebral palsy, with spastic forms being the most common. The motor disorder may range from difficulties with fine motor control to severe spasticity (see MUSCLE SPASTICITY) in all limbs. Spastic diplegia (Little disease) is the most common subtype, and is characterized by spasticity that is more prominent in the legs than in the arms. Pathologically, this condition may be associated with LEUKOMALACIA, PERIVENTRICULAR. (From Dev Med Child Neurol 1998 Aug;40(8):520-7)
Middle Cerebral Artery
A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.
Lysergic Acid Diethylamide
Semisynthetic derivative of ergot (Claviceps purpurea). It has complex effects on serotonergic systems including antagonism at some peripheral serotonin receptors, both agonist and antagonist actions at central nervous system serotonin receptors, and possibly effects on serotonin turnover. It is a potent hallucinogen, but the mechanisms of that effect are not well understood.
Drugs that mimic the effects of parasympathetic nervous system activity. Included here are drugs that directly stimulate muscarinic receptors and drugs that potentiate cholinergic activity, usually by slowing the breakdown of acetylcholine (CHOLINESTERASE INHIBITORS). Drugs that stimulate both sympathetic and parasympathetic postganglionic neurons (GANGLIONIC STIMULANTS) are not included here.
Infarction, Middle Cerebral Artery
NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
A condition characterized by somnolence or coma in the presence of an acute infection with PLASMODIUM FALCIPARUM (and rarely other Plasmodium species). Initial clinical manifestations include HEADACHES; SEIZURES; and alterations of mentation followed by a rapid progression to COMA. Pathologic features include cerebral capillaries filled with parasitized erythrocytes and multiple small foci of cortical and subcortical necrosis. (From Adams et al., Principles of Neurology, 6th ed, p136)
An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
The decrease in a measurable parameter of a PHYSIOLOGICAL PROCESS, including cellular, microbial, and plant; immunological, cardiovascular, respiratory, reproductive, urinary, digestive, neural, musculoskeletal, ocular, and skin physiological processes; or METABOLIC PROCESS, including enzymatic and other pharmacological processes, by a drug or other chemical.
The act of breathing with the LUNGS, consisting of INHALATION, or the taking into the lungs of the ambient air, and of EXHALATION, or the expelling of the modified air which contains more CARBON DIOXIDE than the air taken in (Blakiston's Gould Medical Dictionary, 4th ed.). This does not include tissue respiration (= OXYGEN CONSUMPTION) or cell respiration (= CELL RESPIRATION).
Rats, Inbred Strains
Magnetic Resonance Imaging
Dose-Response Relationship, Drug
The increase in a measurable parameter of a PHYSIOLOGICAL PROCESS, including cellular, microbial, and plant; immunological, cardiovascular, respiratory, reproductive, urinary, digestive, neural, musculoskeletal, ocular, and skin physiological processes; or METABOLIC PROCESS, including enzymatic and other pharmacological processes, by a drug or other chemical.
Antidiuretic hormones released by the NEUROHYPOPHYSIS of all vertebrates (structure varies with species) to regulate water balance and OSMOLARITY. In general, vasopressin is a nonapeptide consisting of a six-amino-acid ring with a cysteine 1 to cysteine 6 disulfide bridge or an octapeptide containing a CYSTINE. All mammals have arginine vasopressin except the pig with a lysine at position 8. Vasopressin, a vasoconstrictor, acts on the KIDNEY COLLECTING DUCTS to increase water reabsorption, increase blood volume and blood pressure.
(11 alpha,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid (PGE(1)); (5Z,11 alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid (PGE(2)); and (5Z,11 alpha,13E,15S,17Z)-11,15-dihydroxy-9-oxoprosta-5,13,17-trien-1-oic acid (PGE(3)). Three of the six naturally occurring prostaglandins. They are considered primary in that no one is derived from another in living organisms. Originally isolated from sheep seminal fluid and vesicles, they are found in many organs and tissues and play a major role in mediating various physiological activities.
The active sympathomimetic hormone from the ADRENAL MEDULLA. It stimulates both the alpha- and beta- adrenergic systems, causes systemic VASOCONSTRICTION and gastrointestinal relaxation, stimulates the HEART, and dilates BRONCHI and cerebral vessels. It is used in ASTHMA and CARDIAC FAILURE and to delay absorption of local ANESTHETICS.
A peptide of about 41 amino acids that stimulates the release of ADRENOCORTICOTROPIC HORMONE. CRH is synthesized by neurons in the PARAVENTRICULAR NUCLEUS of the HYPOTHALAMUS. After being released into the pituitary portal circulation, CRH stimulates the release of ACTH from the PITUITARY GLAND. CRH can also be synthesized in other tissues, such as PLACENTA; ADRENAL MEDULLA; and TESTIS.
Ischemic Attack, Transient
Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)
One of the catecholamine NEUROTRANSMITTERS in the brain. It is derived from TYROSINE and is the precursor to NOREPINEPHRINE and EPINEPHRINE. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (RECEPTORS, DOPAMINE) mediate its action.
Sympathetic Nervous System
The thoracolumbar division of the autonomic nervous system. Sympathetic preganglionic fibers originate in neurons of the intermediolateral column of the spinal cord and project to the paravertebral and prevertebral ganglia, which in turn project to target organs. The sympathetic nervous system mediates the body's response to stressful situations, i.e., the fight or flight reactions. It often acts reciprocally to the parasympathetic system.
Blood Flow Velocity
Anterior Cerebral Artery
Cerebral Amyloid Angiopathy
A heterogeneous group of sporadic or familial disorders characterized by AMYLOID deposits in the walls of small and medium sized blood vessels of CEREBRAL CORTEX and MENINGES. Clinical features include multiple, small lobar CEREBRAL HEMORRHAGE; cerebral ischemia (BRAIN ISCHEMIA); and CEREBRAL INFARCTION. Cerebral amyloid angiopathy is unrelated to generalized AMYLOIDOSIS. Amyloidogenic peptides in this condition are nearly always the same ones found in ALZHEIMER DISEASE. (from Kumar: Robbins and Cotran: Pathologic Basis of Disease, 7th ed., 2005)
Posterior Cerebral Artery
An octapeptide that is a potent but labile vasoconstrictor. It is produced from angiotensin I after the removal of two amino acids at the C-terminal by ANGIOTENSIN CONVERTING ENZYME. The amino acid in position 5 varies in different species. To block VASOCONSTRICTION and HYPERTENSION effect of angiotensin II, patients are often treated with ACE INHIBITORS or with ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS.
Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.
Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
Disease Models, Animal
Tomography, X-Ray Computed
Ventricular Function, Right
Double Outlet Right Ventricle
Incomplete transposition of the great vessels in which both the AORTA and the PULMONARY ARTERY arise from the RIGHT VENTRICLE. The only outlet of the LEFT VENTRICLE is a large ventricular septal defect (VENTRICULAR SEPTAL DEFECTS or VSD). The various subtypes are classified by the location of the septal defect, such as subaortic, subpulmonary, or noncommitted.
Intracranial Embolism and Thrombosis
Heart Defects, Congenital
Abnormal outpouching in the wall of intracranial blood vessels. Most common are the saccular (berry) aneurysms located at branch points in CIRCLE OF WILLIS at the base of the brain. Vessel rupture results in SUBARACHNOID HEMORRHAGE or INTRACRANIAL HEMORRHAGES. Giant aneurysms (>2.5 cm in diameter) may compress adjacent structures, including the OCULOMOTOR NERVE. (From Adams et al., Principles of Neurology, 6th ed, p841)
Microsurgical revascularization to improve intracranial circulation. It usually involves joining the extracranial circulation to the intracranial circulation but may include extracranial revascularization (e.g., subclavian-vertebral artery bypass, subclavian-external carotid artery bypass). It is performed by joining two arteries (direct anastomosis or use of graft) or by free autologous transplantation of highly vascularized tissue to the surface of the brain.
Ventricular Function, Left
Derived from TELENCEPHALON, cerebrum is composed of a right and a left hemisphere. Each contains an outer cerebral cortex and a subcortical basal ganglia. The cerebrum includes all parts within the skull except the MEDULLA OBLONGATA, the PONS, and the CEREBELLUM. Cerebral functions include sensorimotor, emotional, and intellectual activities.
Constriction of arteries in the SKULL due to sudden, sharp, and often persistent smooth muscle contraction in blood vessels. Intracranial vasospasm results in reduced vessel lumen caliber, restricted blood flow to the brain, and BRAIN ISCHEMIA that may lead to hypoxic-ischemic brain injury (HYPOXIA-ISCHEMIA, BRAIN).
Ventricular Dysfunction, Right
A condition in which the RIGHT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE or MYOCARDIAL INFARCTION, and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the right ventricular wall.
Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids.
A reduction in brain oxygen supply due to ANOXEMIA (a reduced amount of oxygen being carried in the blood by HEMOGLOBIN), or to a restriction of the blood supply to the brain, or both. Severe hypoxia is referred to as anoxia, and is a relatively common cause of injury to the central nervous system. Prolonged brain anoxia may lead to BRAIN DEATH or a PERSISTENT VEGETATIVE STATE. Histologically, this condition is characterized by neuronal loss which is most prominent in the HIPPOCAMPUS; GLOBUS PALLIDUS; CEREBELLUM; and inferior olives.
A conical fibro-serous sac surrounding the HEART and the roots of the great vessels (AORTA; VENAE CAVAE; PULMONARY ARTERY). Pericardium consists of two sacs: the outer fibrous pericardium and the inner serous pericardium. The latter consists of an outer parietal layer facing the fibrous pericardium, and an inner visceral layer (epicardium) resting next to the heart, and a pericardial cavity between these two layers.
Transposition of Great Vessels
A congenital cardiovascular malformation in which the AORTA arises entirely from the RIGHT VENTRICLE, and the PULMONARY ARTERY arises from the LEFT VENTRICLE. Consequently, the pulmonary and the systemic circulations are parallel and not sequential, so that the venous return from the peripheral circulation is re-circulated by the right ventricle via aorta to the systemic circulation without being oxygenated in the lungs. This is a potentially lethal form of heart disease in newborns and infants.
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
Image Processing, Computer-Assisted
Restoration of blood supply to tissue which is ischemic due to decrease in normal blood supply. The decrease may result from any source including atherosclerotic obstruction, narrowing of the artery, or surgical clamping. It is primarily a procedure for treating infarction or other ischemia, by enabling viable ischemic tissue to recover, thus limiting further necrosis. However, it is thought that reperfusion can itself further damage the ischemic tissue, causing REPERFUSION INJURY.
Tomography, Emission-Computed, Single-Photon
A method of computed tomography that uses radionuclides which emit a single photon of a given energy. The camera is rotated 180 or 360 degrees around the patient to capture images at multiple positions along the arc. The computer is then used to reconstruct the transaxial, sagittal, and coronal images from the 3-dimensional distribution of radionuclides in the organ. The advantages of SPECT are that it can be used to observe biochemical and physiological processes as well as size and volume of the organ. The disadvantage is that, unlike positron-emission tomography where the positron-electron annihilation results in the emission of 2 photons at 180 degrees from each other, SPECT requires physical collimation to line up the photons, which results in the loss of many available photons and hence degrades the image.
Magnetic Resonance Angiography
A noninvasive technique that uses the differential absorption properties of hemoglobin and myoglobin to evaluate tissue oxygenation and indirectly can measure regional hemodynamics and blood flow. Near-infrared light (NIR) can propagate through tissues and at particular wavelengths is differentially absorbed by oxygenated vs. deoxygenated forms of hemoglobin and myoglobin. Illumination of intact tissue with NIR allows qualitative assessment of changes in the tissue concentration of these molecules. The analysis is also used to determine body composition.
Hypertrophy, Right Ventricular
Heart Septal Defects, Ventricular
Developmental abnormalities in any portion of the VENTRICULAR SEPTUM resulting in abnormal communications between the two lower chambers of the heart. Classification of ventricular septal defects is based on location of the communication, such as perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular defect.
Adult subventricular zone neuronal precursors continue to proliferate and migrate in the absence of the olfactory bulb. (1/1602)Neurons continue to be born in the subventricular zone (SVZ) of the lateral ventricles of adult mice. These cells migrate as a network of chains through the SVZ and the rostral migratory stream (RMS) into the olfactory bulb (OB), where they differentiate into mature neurons. The OB is the only known target for these neuronal precursors. Here, we show that, after elimination of the OB, the SVZ and RMS persist and become dramatically larger. The proportion of dividing [bromodeoxyuridine (BrdU)-labeled] or dying (pyknotic or terminal deoxynucleotidyl transferase-mediated biotinylated UTP nick end-labeled) cells in the RMS was not significantly affected at 3 d or 3 weeks after bulbectomy (OBX). However, by 3 months after OBX, the percentage of BrdU-labeled cells in the RMS decreased by half and that of dying cells doubled. Surprisingly, the rostral migration of precursors continued along the RMS after OBX. This was demonstrated by focal microinjections of BrdU and grafts of SVZ cells carrying LacZ under the control of a neuron-specific promoter gene. Results indicate that the OB is not essential for proliferation and the directional migration of SVZ precursors. (+info)
Effect of individual or combined ablation of the nuclear groups of the lamina terminalis on water drinking in sheep. (2/1602)The subfornical organ (SFO), organum vasculosum of the lamina terminalis (OVLT), and median preoptic nucleus (MnPO) were ablated either individually or in various combinations, and the effects on drinking induced by either intravenous infusion of hypertonic 4 M NaCl (1.3 ml/min for 30 min) or water deprivation for 48 h were studied. Ablation of either the OVLT or SFO alone did not affect drinking in response to intravenous 4 M NaCl, although combined ablation of these two circumventricular organs substantially reduced but did not abolish such drinking. Ablation of the MnPO or MnPO and SFO together also substantially reduced, but did not abolish, drinking in response to intravenous hypertonic NaCl. Only near-total destruction of the lamina terminalis (OVLT, MnPO, and part or all of the SFO) abolished acute osmotically induced drinking. The large lesions also reduced drinking after water deprivation, whereas none of the other lesions significantly affected such drinking. None of these lesions altered feeding. The results show that all parts of the lamina terminalis play a role in the drinking induced by acute increases in plasma tonicity. The lamina terminalis appears to play a less crucial role in the drinking response after water deprivation than for the drinking response to acute intravenous infusion of hypertonic saline. (+info)
Volumetric change of the lateral ventricles in the human brain following glucose loading. (3/1602)Lateral ventricular volumes were monitored and quantified using accurately registered magnetic resonance images (MRIs) in six healthy individuals 30 min before and up to 4 h after ingestion of a glucose drink. The volume of the lateral ventricles increased by an average (+/- S.E.M.) of 2.4 +/- 0.4% as blood glucose levels rose from 4.8 +/- 0.2 mmol l-1 to 8.4 +/- 0.4 mmol l-1. This was followed by a peak decrease of 5.99 +/- 3.3% below initial fasting volumes as blood glucose levels fell to 5.0 +/- 0.3 mmol l-1. We suggest that the secondary volume decrease demonstrates a homeostatic process of brain volume regulation for which the mechanism remains uncertain. (+info)
Hyaline membrane disease, alkali, and intraventricular haemorrhage. (4/1602)The relation between intraventricular haemorrhage (IVH) and hyaline membrane disease (HMD) was studied in singletons that came to necropsy at Hammersmith Hospital over the years 1966-73. The incidence of IVH in singleton live births was 3-22/1000 and of HMD 4-44/1000. Although the high figures were partily due to the large number of low birthweight infants born at this hospital, the incidence of IVH in babies weighing 1001-1500 g was three times as great as that reported in the 1658 British Perinatal Mortality Survey. Most IVH deaths were in babies with HMD, but the higher frequency of IVH was not associated with any prolongation of survival time of babies who died with HMD as compared with the 1958 survey. IVH was seen frequently at gestations of up to 36 weeks in babies with HMD but was rare above 30 weeks' gestation in babies without HMD. This indicated that factors associated with HMD must cause most cases of IVH seen at gestations above 30 weeks. Comparison of clinical details in infants with HMD who died with or without IVH (at gestations of 30-37 weeks) showed no significant differences between the groups other than a high incidence of fits and greater use of alkali therapy in the babies with IVH. During the 12 hours when most alkali therapy was given, babies dying with IVD received a mean total alkali dosage of 10-21 mmol/kg and those dying without IVH 6-34 mmol/kg (P less than 0-001). There was no difference in severity of hypoxia or of metabolic acidosis between the 2 groups. Babies who died with HMD and germinal layer haemorrhage (GLH) without IVH had received significantly more alkali than those who died with HMD alone, whereas survivors of severe respiratory distress syndrome had received lower alkali doses than other groups. It is suggested that the greatly increased death rate from IVH in babies with HMD indicates some alteration of management of HMD (since 1958) as a causative factor. Liberal use of hypertonic alkali solutions is the common factor which distinguishes babies dying with GLH and IVH from other groups of babies with HMD. Although the causal nature of this association remains unproved, it seems justifiable to lrge caution in alkali usage. (+info)
Apparent loss and hypertrophy of interneurons in a mouse model of neuronal ceroid lipofuscinosis: evidence for partial response to insulin-like growth factor-1 treatment. (5/1602)The neuronal ceroid lipofuscinoses (NCL) are progressive neurodegenerative disorders with onset from infancy to adulthood that are manifested by blindness, seizures, and dementia. In NCL, lysosomes accumulate autofluorescent proteolipid in the brain and other tissues. The mnd/mnd mutant mouse was first characterized as exhibiting adult-onset upper and lower motor neuron degeneration, but closer examination revealed early, widespread pathology similar to that seen in NCL. We used the autofluorescent properties of accumulated storage material to map which CNS neuronal populations in the mnd/mnd mouse show NCL-like pathological changes. Pronounced, early accumulation of autofluorescent lipopigment was found in subpopulations of GABAergic neurons, including interneurons in the cortex and hippocampus. Staining for phenotypic markers normally present in these neurons revealed progressive loss of staining in the cortex and hippocampus of mnd/mnd mice, with pronounced hypertrophy of remaining detectable interneurons. In contrast, even in aged mutant mice, many hippocampal interneurons retained staining for glutamic acid decarboxylase. Treatment with insulin-like growth factor-1 partially restored interneuronal number and reduced hypertrophy in some subregions. These results provide the first evidence for the involvement of interneurons in a mouse model of NCL. Moreover, our findings suggest that at least some populations of these neurons persist in a growth factor-responsive state. (+info)
A quantitative MR study of the hippocampal formation, the amygdala, and the temporal horn of the lateral ventricle in healthy subjects 40 to 90 years of age. (6/1602)BACKGROUND AND PURPOSE: Several investigators have defined normal age-specific values for the medial temporal lobe structures in neurologically normal elderly subjects, but, to our knowledge, no one has reported those values for a large sample of healthy volunteers. The purpose of our study was to define normal age-specific values for the hippocampal formation, the amygdala, and the temporal horn of the lateral ventricle by age group, ranging from 40 to 90 years, in order to generate a guideline for the quantitative MR diagnosis and differential diagnosis for early Alzheimer disease. METHODS: MR-based volumetric measurements of the hippocampal formation, the amygdala, and the temporal horn, standardized by total intracranial volume, were obtained from oblique coronal and sagittal T1-weighted MR images in 619 healthy volunteers and two cadaveric specimens. RESULTS: Differences in standardized volumes of the hippocampal formation, the amygdala, and the temporal horn were significant among the 61- to 70-year-old, 71- to 80-year-old, and 81- to 90-year-old groups, and were not significant between the 40- to 50-year-old and 51- to 60-year-old groups. We found no significant differences in side or sex among the age groups for any of the structures. CONCLUSION: Differences in the mean value and in the 95% normal range of standardized volumes of the hippocampal formation, the amygdala, and the temporal horn correspond to differences in age among healthy subjects; therefore, age should be considered a factor in correlative research, especially in that involving patients in the early stages of Alzheimer disease. (+info)
Blood pressure reduction and diabetes insipidus in transgenic rats deficient in brain angiotensinogen. (7/1602)Angiotensin produced systemically or locally in tissues such as the brain plays an important role in the regulation of blood pressure and in the development of hypertension. We have established transgenic rats [TGR(ASrAOGEN)] expressing an antisense RNA against angiotensinogen mRNA specifically in the brain. In these animals, the brain angiotensinogen level is reduced by more than 90% and the drinking response to intracerebroventricular renin infusions is decreased markedly compared with control rats. Blood pressure of transgenic rats is lowered by 8 mmHg (1 mmHg = 133 Pa) compared with control rats. Crossbreeding of TGR(ASrAOGEN) with a hypertensive transgenic rat strain exhibiting elevated angiotensin II levels in tissues results in a marked attenuation of the hypertensive phenotype. Moreover, TGR(ASrAOGEN) exhibit a diabetes insipidus-like syndrome producing an increased amount of urine with decreased osmolarity. The observed reduction in plasma vasopressin by 35% may mediate these phenotypes of TGR(ASrAOGEN). This new animal model presenting long-term and tissue-specific down-regulation of angiotensinogen corroborates the functional significance of local angiotensin production in the brain for the central regulation of blood pressure and for the pathogenesis of hypertension. (+info)
Recovery from anterograde and retrograde amnesia after percutaneous drainage of a cystic craniopharyngioma. (8/1602)A case is reported of a cystic craniopharyngioma involving the floor and walls of the third ventricle. Pronounced anterograde and retrograde amnesia were documented preoperatively by formal testing. Rapid improvement in both new learning capacity and remote memory occurred after percutaneous twist drill drainage of the cystic portion of the tumour. The relevance of these observations to the amnesic syndrome and its neuropathological basis is discussed. (+info)
Attenuated vascular reactivity in dogs with anteroventral third ventricle lesions. | Hypertension
Lesion of the anteroventral portion of the third cerebral ventricle causes hypernatremia, adipsia, and attenuation of the pressor response to intravenous administration of angiotensin II and norepinephrine. In addition, these lesions prevent the development of several experimental models of hypertension. In this study, a lesion of the third cerebral ventricle region was made in 14 dogs. In seven dogs in which hypernatremia developed the lesions included the organum vasculosum of the lamina terminalis; seven animals in which the circumventricular organ was spared by the lesion remained normonatremic. Vascular responsiveness of isolated right carotid artery rings to angiotensin II and phenylephrine was assessed 3 days after lesioning the anteroventral portion of the third cerebral ventricle. In endothelium-denuded ring vessels, vasoconstrictor responses to phenylephrine were significantly decreased in animals both with and without inclusion of the organum vasculosum of the lamina terminalis. A ...
Functional antagonism of alpha-subunits of Kv channel in developing brain ventricular system | Development
The brain ventricular system is essential for neurogenesis and brain homeostasis. Its neuroepithelial lining effects these functions, but the underlying molecular pathways remain to be understood. We found that the K channels expressed in neuroepithelial cells determine formation of the ventricular system. The phenotype of a novel zebrafish mutant characterized by denudation of neuroepithelial lining of the ventricular system and hydrocephalus is mechanistically linked to Kcng4b, the homologue of the silent voltage-gated K channel alpha-subunit Kv6.4. We demonstrated that Kcng4b modulates proliferation of cells lining the ventricular system and maintains their integrity. The gain of Kcng4b function reduces brain ventricles. Electrophysiological studies supported an idea that Kcng4b mediates its effects via an antagonistic interaction with Kcnb1, the homologue of the electrically active delayed rectifier K channel subunit Kv2.1. The mutation of kcnb1 reduces the size of ventricular system and ...
Proliferation and migration of subventricular zone cells in intact adult mice and after cortical lesions - Immunology
Faculty | People | CSBi | Computational and Systems Biology at MIT
One unique feature of the vertebrate brain is that it is tubular. The lumen of the tube is filled with cerebrospinal fluid (CSF), and forms the brain ventricular system, a circulatory system within the brain. Ventricular abnormalities lead to devastating brain disorders such as anencephaly and hydrocephalus. The embryonic development and function of this system are poorly understood. We analyze embryonic brain ventricle development in the zebrafish, an excellent system, as imaging the brain at single cell resolution in living embryos is feasible, and as many brain ventricle mutants have been identified. Brain ventricles form over a six-hour period, during mid-somitogenesis, and require normal junctions and ion pump activity. Thus, mutants in nagie oko, which encodes a MAGUK family protein, with no clear midline and disrupted epithelial junctional protein expression fail to inflate their ventricles. In the snakehead mutant brain, the ventricles also do not inflate due to a mutation in the NaK ...
Neil, Beth, Iain and Liam Pitman: May 2009
The appointment yesterday went well. Ventricle size is still enlarged and is not showing a decrease at all, but the doctors do feel that although the condition is serious it is stable (no huge spikes in the amount of fluid). The babys head size is within the normal range so the doctors feel good about a natural delivery, which is positive. The baby is doing well apart from the ventriculomegaly, so this is also positive. Current estimated weight is 8lbs 11oz! This being the case (combined with babys condition) - if Baby Pitman decides not to come by May 20th Beth will be induced. We are still delivering in Iowa City and baby will go to the NICU shortly after birth. We are still hopeful for a reduction in ventricle size after birth. Surgery is still a possibility at this point, but this wont be decided until the baby can be evaluated outside of the womb. We are hoping that this can be avoided, but of course we will do whatever is best for baby! Infant brain surgery just sounds, well, a little ...
Intraventricular Hemorrhage in Babies
Intraventricular hemorrhage (IVH) is bleeding inside or around the ventricles in the brain. The ventricles are the spaces in the brain that contain the cerebral spinal fluid.
Agnesian HealthCare - Intraventricular Hemorrhage in Babies
Intraventricular hemorrhage (IVH) is bleeding inside or around the ventricles in the brain. The ventricles are the spaces in the brain that contain the cerebral spinal fluid.
The tumor cells invade the ventricular system.A- Septo- | Open-i
The tumor cells invade the ventricular system.A- Septo-Striatal section, phase contrast (tissue slides, 1X); B- The same Septo-Striatal section: Ki-67 (red) ove
Guest Post by Dr. Manuel Casanova: Enlargement of the Brain Ventricles in Preterm Infants and Autism: An Ultrasound Study |...
Since Im going to be out of town on vacation for the next several weeks traveling over to England, my fiancé, Dr. Manuel Casanova, will be providing one or two guest posts to fill the SoaC void. As a recap for those whove forgotten, or for those who didnt read his first guest post on…
Cerebral Ventricles And Vessels - Anatomy Diagram Charts
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Intraventricular Hemorrhage | Conditions & Treatments | UCSF Benioff Childrens Hospital
Other than trying to prevent premature birth and treating health problems that may worsen a babys condition and increase the risk of IVH, theres no specific treatment for the condition. However, giving mothers medications called corticosteroids before delivery has been shown to reduce the risk of IVH in babies.. If the IVH is severe enough that the ventricles in the brain enlarge and put the surrounding brain at risk for damage, a shunt may be required to drain the excess fluid that has built up in the ventricles. A shunt is placed by a surgical procedure, and it drains the excess fluid from the ventricles in the brain under the skin to the abdomen.. ...
MRI-monitored cord blood-derived cell transplantation to the ventricular system of child with global cerebral ischemia-a case...
Tytuł projektu: Rozbudowa i przekształcenie bibliograficznej bazy danych AGRO w bazę bibliograficzno-abstraktową z wykorzystaniem oprogramowania YADDA. Nr umowy: POIG 02.03.02-00-031/09 (okres realizacji 2009-2013 ...
I Never Imagined: May 2009
One of the major risks for premature babies is Intraventricular Hemorrhage. The blood vessels in their brain are so delicate that they burst and bleeding occurs in the ventricles of the brain. This happened to Clayton on his fifth day of life. He had grades three and four bleeds (four being the worst). As the blood dissolves and breaks down in the ventricles, it starts to block the natural flow of cerebrospinal fluid (CSF). Normally the CSF flows from the ventricles down through the spinal cord and is absorbed by the body. This is a natural cycle that occurs in everyones body. Claytons body seemed to handle the bleeds well at first. His ventricles stayed a normal size for quite some time before we started to see problems. But after about a month, his ventricles started to enlarge because the CSF wasnt flowing out. The neurosurgeons started doing daily spinal taps to help move the CSF. Eventually even this stopped working. The doctors had to start drawing the CSF directly out of Claytons head ...
Dynamic features of postnatal subventricular zone cell motility: a two-photon time-lapse study. - Physiology, Anatomy and...
Neuroblasts migrate long distances in the postnatal subventricular zone (SVZ) and rostral migratory stream (RMS) to the olfactory bulbs. Many fundamental features of SVZ migration are still poorly understood, and we addressed several important questions using two-photon time-lapse microscopy of brain slices from postnatal and adult eGFP(+) transgenic mice. 1) Longitudinal arrays of neuroblasts, so-called chain migration, have never been dynamically visualized in situ. We found that neuroblasts expressing doublecortin-eGFP (Dcx-eGFP) and glutamic acid decarboxylase-eGFP (Gad-eGFP) remained within arrays, which maintained their shape for many hours, despite the fact that there was a wide variety of movement within arrays. 2) In the dorsal SVZ, neuroblasts migrated rostrocaudally as expected, but migration shifted to dorsoventral orientations throughout ventral regions of the lateral ventricle. 3) Whereas polarized bipolar morphology has been a gold standard for inferring migration in histologic sections,
Mixing and Modes of Mass Transfer in the Third Cerebral Ventricle: A Computational Analysis | Journal of Biomechanical...
Anatomic, velocimetric, and brain motion MRI scans were combined with a computational fluid dynamics model to investigate cerebrospinal fluid (CSF) mixing in the third cerebral ventricle of a healthy male adult. It was found that advection dominates over diffusion in most of the third ventricle. Three zones where diffusion plays an important role in the mixing process were identified. One of these zones, consisting of recessus infundibulus, recessus opticus and the adjacent regions up to commissura anterior, is likely to exist in the general population. We hypothesize that this zone may act as a buffer to flatten concentration peaks of pituitary gland hormones released into the CSF of the third ventricle. We further hypothesize that this zone may facilitate the communication between hypothalamus and the pituitary gland through the third ventricle cerebrospinal fluid by prolonging residence times of the communicated hormones. ...
β-catenin signaling promotes proliferation of progenitor cells in the adult mouse subventricular zone<...
TY - JOUR. T1 - β-catenin signaling promotes proliferation of progenitor cells in the adult mouse subventricular zone. AU - Adachi, Kazuhide. AU - Mirzadeh, Zaman. AU - Sakaguchi, Masanori. AU - Yamashita, Toru. AU - Nikolcheva, Tania. AU - Gotoh, Yukiko. AU - Peltz, Gary. AU - Gong, Leyi. AU - Kawase, Takeshi. AU - Alvarez-Buylla, Arturo. AU - Okano, Hideyuki. AU - Sawamoto, Kazunobu. PY - 2007/11. Y1 - 2007/11. N2 - The subventricular zone (SVZ) is the largest germinal zone in the mature rodent brain, and it continuously produces young neurons that migrate to the olfactory bulb. Neural stem cells in this region generate migratory neuroblasts via highly proliferative transit-amplifying cells. The Wnt/β-catenin signaling pathway partially regulates the proliferation and neuronal differentiation of neural progenitor cells in the embryonic brain. Here, we studied the role of β-catenin signaling in the adult mouse SVZ. β-Catenin-dependent expression of a destabilized form of green fluorescent ...
Fibrinolytic therapy for intraventricular hemorrhage in adults.<...
TY - JOUR. T1 - Fibrinolytic therapy for intraventricular hemorrhage in adults.. AU - Lapointe, M.. AU - Haines, S.. PY - 2002. Y1 - 2002. N2 - BACKGROUND: Spontaneous or secondary intraventricular hemorrhage is a marker of poor prognosis for hemorrhagic stroke. It can cause hydrocephalus and require ventricular shunt placement, result in permanent neurological deficits or death. Fibrinolytic agents injected into the ventricular system could dissolve blood clots, increase the clearance of blood from the ventricles and hence improve outcome. OBJECTIVES: To assess the clinical efficacy and safety of thrombolytic agents administered intraventricularly in the management of intraventricular hemorrhage in adults. SEARCH STRATEGY: We searched the Cochrane Stroke Group Trials Register (last searched February 2002). In addition, we searched the Cochrane Controlled Trials Register, MEDLINE, EMBASE, Current Contents, and International Pharmacy Abstracts to 2001. We handsearched several neurosurgery ...
Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage Phase III - Full Text View - ClinicalTrials.gov
The overall objective of this Phase III clinical trial is to obtain information from a population of 500 ICH subjects with intraventricular hemorrhage (IVH), representative of current clinical practice and national demographics of ICH regarding the benefit (or lack thereof) of IVH clot removal on subject function as measured by modified Rankin Scale (mRS). This application requests funding for five years to initiate a Phase III randomized clinical trial (RCT) testing the benefit of clot removal for intraventricular hemorrhage. The investigators propose to compare extraventricular drainage (EVD) use plus recombinant tissue plasminogen activator (rt-PA; Alteplase; Genentech, Inc., San Francisco, CA) with EVD+ placebo in the management and treatment of subjects with small intracerebral hemorrhage (ICH) and large intraventricular hemorrhage (IVH defined as ICH , 30 cc and obstruction of the 3rd or 4th ventricles by intraventricular blood clot ...
Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage Phase III - Mayo Clinic
The overall objective of this Phase III clinical trial is to obtain information from a population of 500 ICH subjects with intraventricular hemorrhage (IVH), representative of current clinical practice and national demographics of ICH regarding the benefit (or lack thereof) of IVH clot removal on subject function as measured by modified Rankin Scale (mRS). This application requests funding for five years to initiate a Phase III randomized clinical trial (RCT) testing the benefit of clot removal for intraventricular hemorrhage. The investigators propose to compare extraventricular drainage (EVD) use plus recombinant tissue plasminogen activator (rt-PA; Alteplase; Genentech, Inc., San Francisco, CA and Boehringer Ingelheim, Inc., Ingelheim, Germany) with EVD+ placebo in the management and treatment of subjects with small intracerebral hemorrhage (ICH) and large intraventricular hemorrhage (IVH defined as ICH < 30 cc and obstruction of the 3rd or 4th ventricles by intraventricular blood ...
Amoeboid microglia in the periventricular white matter induce oligodendrocyte damage through expression of proinflammatory...
Kaur, C., Deng, Y., Sivakumar, V., Ling, E.A., Lu, J. (2008). Amoeboid microglia in the periventricular white matter induce oligodendrocyte damage through expression of proinflammatory cytokines via MAP kinase signaling pathway in hypoxic neonatal rats. Brain Pathology 18 (3) : 387-400. [email protected] Repository. https://doi.org/10.1111/j.1750-3639.2008.00138. ...
Germinal matrix hemorrhage
The germinal matrix is the site of proliferating neuronal and glial precursors in the developing brain, which is located above the caudate nucleus, in the floor of the lateral ventricle, and caudothalamic groove. The germinal matrix contains a rich network of fragile thin-walled blood vessels. Hence the microcirculation in this particular area is extremely sensitive to hypoxia and changes in perfusion pressure. It is most frequent before 35 weeks gestation and is typically seen in very low birth-weight (,1500g) premature infants, because they lack the ability for auto regulation of cerebral blood flow. Consequently, increased arterial blood pressure in these blood vessels leads to rupture and hemorrhage into germinal matrix.. ...
Limited distribution of pertussis toxin in rat brain after injection into the lateral cerebral ventricles. - Semantic Scholar
In vivo administration of pertussis toxin is often used to study the involvement of guanine nucleotide binding proteins in signal transduction. Especially when it is administered in the brain the effect is often poor. This could be due to the fact that pertussis toxin does not reach the area of interest. To evaluate the extent to which pertussis toxin is distributed in rat brain after intraventricular injection, different techniques were used. Immunohistochemical studies with an antibody against pertussis toxin showed that immunoreactivity was limited to periventricular brain structures less than 0.5 mm from the lumen. The highest immunoreactivity was seen 16-24 h after injection. After 96 h the labeling was very weak. The proportion of guanine nucleotide binding proteins that were ADP-ribosylated by in vivo injection of pertussis toxin into the ventricles as assessed by in vitro [32P]-back-ADP-ribosylation was very low 48 h after the injection, in all regions studied. Direct injection of pertussis
Prognostic significance of delayed intraventricular haemorrhage in the INTERACT studies<...
TY - JOUR. T1 - Prognostic significance of delayed intraventricular haemorrhage in the INTERACT studies. AU - Moullaali, Tom J.. AU - Sato, Shoichiro. AU - Wang, Xia. AU - Rabinstein, Alejandro A.. AU - Arima, Hisatomi. AU - Carcel, Cheryl. AU - Chen, Guofang. AU - Robinson, Thompson. AU - Heeley, Emma. AU - Chan, Edward. AU - Delcourt, Candice. AU - Stapf, Christian. AU - Cordonnier, Charlotte. AU - Lindley, Richard I.. AU - Chalmers, John. AU - Anderson, Craig S.. PY - 2017/1/1. Y1 - 2017/1/1. N2 - Background and purpose Intraventricular extension of intracerebral haemorrhage (ICH) predicts poor outcome, but the significance of delayed intraventricular haemorrhage (dIVH) is less well defined. We determined the prognostic significance of dIVH in the Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage Trials (INTERACT 1 and 2). Methods Pooled analyses of the INTERACT CT substudies - international, multicentre, prospective, open, blinded end point, randomised controlled trials of ...
Messaging by flow in the brain | Max Planck Institute for Biophysical Chemistry
Cilia free our airways of dust, mucus, and pathogens, transport egg cells through the fallopian tubes, and help sperm to move forward. The four chambers in our brain, so-called cerebral ventricles, are also lined with a layer of highly specialized cells covered with bundles of cilia on their surface. Although each one is just a few thousandths of a millimeter in size, hundreds of them beating in unison can generate powerful flows.. Gregor Eichele and Regina Faubel at the Max Planck Institute (MPI) for Biophysical Chemistry, together with Eberhard Bodenschatz and Christian Westendorf at the MPI for Dynamics and Self-Organization, have now succeeded in making the complex network of these flows visible in an isolated cerebral ventricle tissue. For their experiments, the researchers in Göttingen concentrated on the third cerebral ventricle, which is embedded in the hypothalamus. The hypothalamus is a very important control center, regulating functions like the circulatory system, body temperature, ...
Neocortical atrophy, third ventricular width, and cognitive dysfunction in multiple sclerosis.
Abstract BACKGROUND: Cognitive dysfunction is common in multiple sclerosis (MS). Correlations are reported between atrophy and neuropsychological test results. OBJECTIVE: To determ..
Natural history of ventriculomegaly in adults: a cluster analysis in: Journal of Neurosurgery Volume 132 Issue 3 (2019)
Chronic ventriculomegaly in the absence of raised intracranial pressure (ICP) is a known entity in adult hydrocephalus practice. The natural history and indication for treatment is, however, poorly defined. A highly heterogeneous group, some adults with ventriculomegaly are asymptomatic, while others have life-threatening deteriorations. The authors hypothesized that the various presentations can be subtyped and represent different stages of decompensation. A cluster analysis was performed on a cohort of patients with chronic ventriculomegaly with the aim of elucidating typical clinical characteristics and outcomes in chronic ventriculomegaly in adults. ...
Recommended Readings on Hydrocephalus After Intraventricular Hemorrhage in Infants
Duncan C, Chiang V: Intraventricular hemorrhage and posthemorrhagic hydrocephalus, in Albright A, Pollack I, Adelson P (eds): Principles and Practice of Pediatric Neurosurgery, ed 2. New York: Thieme Medical Publishers, Inc, 2008, vol 2, pp 145- ...
11/22/2007 - Sawamoto Lab 澤本研究室
The Journal of Neuroscience, November 21, 2007, 27(47):12829-12838. Cyclin-Dependent Kinase 5 Is Required for Control of Neuroblast Migration in the Postnatal Subventricular Zone. Yuki Hirota, Toshio Ohshima, Naoko Kaneko, Makiko Ikeda, Takuji Iwasato, Ashok B. Kulkarni, Katsuhiko Mikoshiba, Hideyuki Okano, and Kazunobu Sawamoto. At the lateral wall of the lateral ventricles in the adult rodent brain, neuroblasts form an extensive network of elongated cell aggregates called chains in the subventricular zone and migrate toward the olfactory bulb. The molecular mechanisms regulating this migration of neuroblasts are essentially unknown. Here, we report a novel role for cyclin-dependent kinase 5 (Cdk5), a neuronal protein kinase, in this process. Using in vitro and in vivo conditional knock-out experiments, we found that Cdk5 deletion impaired the chain formation, speed, directionality, and leading process extension of the neuroblasts in a cell-autonomous manner. These findings suggest that Cdk5 ...
How Is Neonatal Intraventricular Hemorrhage Classified | SeekHealthZ
How is neonatal intraventricular hemorrhage classified? Grade I: Localized subependymal hemorrhage into the germinal matrix Grade II: Subependymal hemorrhage
abnormal heart right ventricle size Mammalian Phenotype Term (MP:0010577)
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Computational modeling of the cerebral ventricular cerebrospinal fluid system - Research Collection
ZEREBROSPINALFLÜSSIGKEIT (PHYSIOLOGIE, NEUROLOGIE); FLUIDDYNAMIK; KERNSPINRESONANZ-ABBILDUNGSVERFAHREN + KERNSPINRESONANZ-TOMOGRAPHIE (MEDIZINISCHE DIAGNOSTIK); MODELLRECHNUNG UND SIMULATION IN DER PHYSIOLOGIE; CEREBROSPINAL FLUID (PHYSIOLOGY, NEUROLOGY); FLUID DYNAMICS; NUCLEAR MAGNETIC RESONANCE IMAGING + NUCLEAR MAGNETIC RESONANCE TOMOGRAPHY (MEDICAL DIAGNOSTICS); MATHEMATICAL MODELING AND SIMULATION IN ...
Understanding Intraventricular Hemorrhage (IVH) in Preemies
Intraventricular hemorrhage (IVH) is a serious complication that can occur in premature infants. Learn more about IVH and related complications.
Intraventricular Hemorrhage | Johns Hopkins Medicine
Intraventricular hemorrhage (IVH) of the newborn is bleeding into the fluid-filled areas, or ventricles, surrounded by the brain. The condition is most often seen in premature babies, and the smaller and more premature the infant, the higher the risk for IVH.
Physiological Disturbances Associated With Neonatal Intraventricular Hemorrhage - Full Text View - ClinicalTrials.gov
Annually, almost 5,000 extremely low birth weight (9 ounces to about 2 lbs) infants born in the US survive with severe bleeding in the brain (intraventricular hemorrhage); this devastating complication of prematurity is associated with many problems, including mental retardation, cerebral palsy, and learning disabilities, that result in profound individual and familial consequences. In addition, lifetime care costs for these severely affected infants born in a single year exceed $3 billion. The huge individual and societal costs underscore the need for developing care strategies that may limit severe bleeding in the brain of these tiny infants. The overall goal of our research is to evaluate disturbances of brain blood flow in these tiny infants in order to predict which of them are at highest risk and to develop better intensive care techniques that will limit severe brain injury.. ...
Germinal matrix hemorrhage - grading of intracranial bleeding in neonates | Classifications, online calculators, and tables in...
Grading of intracranial hemorrhage in neonates is based on ultrasound imaging. It has four grades with increasing mortality and decreasing outcome.
In vitro generation of dopaminergic neurons from adult subventricular zone neural progenitor cells. - PubMed - NCBI
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Intraventricular Hemorrhage of Infancy | Reston Hospital Center
Learn more about Intraventricular Hemorrhage of Infancy at Reston Hospital Center DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
Intraventricular Hemorrhage (IVH)
Bleeding may occur in the part of the brain containing most of the cerebral spinal fluid (CSF). This compartment is the ventricular system. Sometimes these hemorrhages cause obstructive hydrocephalus.
Evidence of ventricular contamination of the optical signal in preterm neonates with post hemorrhagic ventricle dilation | ...
Dilation of the cerebral ventricles is a common condition in preterm neonates with intraventricular hemorrhage (IVH). This post hemorrhagic ventricle dilation (PHVD) can lead to lifelong neurological impairment through ischemic injury due to increased intracranial pressure (ICP). Interventions, such as ventricular tapping to remove cerebrospinal fluid (CSF), are used to prevent injury, but determining the optimal time for treatment is difficult as clinical signs of increased ICP lack sensitivity. There is a growing interest in using near-infrared spectroscopy (NIRS) because of its ability to monitor cerebral oxygen saturation (StO2) at the bedside. However, the accuracy of NIRS may be affected by signal contamination from enlarged ventricles, especially if there are blood breakdown products (bbp) in CSF following IVH. To investigate this, serial NIR spectra from the head and from CSF samples were acquired over a month from seven IVH patients undergoing treatment for PHVD. Over time, the visual ...
The ventricular spaces in the various subdivisions of the brain reflects the fact that the ventricles are the adult derivatives of the open space of the embryonic neural tube. The two lateral ventricles, situated within the cerebrum, are relatively large and C-shaped, and roughly wraps around the dorsal aspects of the basal ganglia. In the lateral ventricles of the embryo the successive generation of neurons gives rise to the 6-layered structure of the neocortex, constructed from the inside out during development. ...
Periventricular Leukomalacia (PVL) in Children
Periventricular leukomalacia (PVL) is a softening of white brain tissue near the ventricles. The ventricles are fluid-filled chambers in the brain.
Precursor diversity and complexity of lineage relationships in the outer subventricular zone of the primate
Long-term ex vivo live imaging combined with unbiased sampling of cycling precursors shows that macaque outer subventricular zone (OSVZ) includes four distinct basal radial glial (bRG) cell morphotypes, bearing apical and/or basal processes in addition to nonpolar intermediate progenitors (IPs). Eac …
Survival and proliferation of nonneural tissues, with obstruction of cerebral ventricles, in a parkinsonian patient treated...
I prepared (or cooperated in the preparation of) the Work as part of my duties as an employee, and the Work is, therefore, a work made for hire, as defined by the United States Copyright Act of 1976, as amended ...
Statistical Multiplexing and Quality of Service Control of VBR Mpeg Video Sources | Sciweavers
Statistical Multiplexing and Quality of Service Control of VBR Mpeg Video Sources - In this paper efficient modeling of VBR MPEG coded video sources is proposed by appropriately combining properties of frame and GOP layer signals. In particular, a Markov chain is presented for modeling the video activity, the states of which correspond to correlated AR models responsible for generating the I, P and B frames. Furthermore, an adaptive implementation of the AR coefficients is accomplished in cases that we are interested in video traffic prediction. Experimental results using long duration sequences are provided to indicate the good performance of the proposed modeling scheme.
Search Results | jns
Patients diagnosed with DIPG and treated with up-front radiation therapy (RT) at The Hospital for Sick Children between 2000 and 2019 were identified. Images at diagnosis and progression were used to determine the frontal/occipital horn ratio (FOR) as a method to measure ventricular size. Patients with ventriculomegaly (FOR ≥ 0.36) were stratified according to the presence of symptoms and categorized as follows: 1) asymptomatic ventriculomegaly and 2) symptomatic hydrocephalus. For patients with ventriculomegaly who did not require CSF diversion, post-RT imaging was also evaluated to assess changes in the FOR after RT. Proportional hazards analyses were used to identify clinical and treatment factors correlated with survival. The Kaplan-Meier method was used to perform survival estimates, and the log-rank method was used to identify survival differences between groups. ...
Longitudinal whole-brain atrophy and ventricular enlargement in nondemented Parkinsons disease - pdf descargar
Longitudinal whole-brain atrophy and ventricular enlargement in nondemented Parkinsons disease. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
Positive T wave overshoot as a sign of ventricular enlargement...
Positive T wave overshoot as a sign of ventricular enlargement.: A consecutive series of 86 patients with an inverted T wave showing terminal positivity (oversh
Childrens Hospital of The Kings Daughters Health System
Periventricular leukomalacia (PVL) is a softening of white brain tissue near the ventricles. The ventricles are fluid-filled chambers in the brain. These are the spaces in the brain that contain the cerebrospinal fluid (CSF). The white matter is the inner part of the brain. It sends information between the nerve cells and the spinal cord, and from one part of the brain to another. PVL occurs because brain tissue has been injured or has died. A lack of blood flow to the brain tissue before, during, or after birth causes PVL. It is rarely possible to tell when or why this happens. PVL is sometimes linked to bleeding inside the brain (intraventricular hemorrhage). PVL can occur in babies who are born early (preterm or premature). ...
Fetal Ventriculomegaly | Parthenon Pavilion
Learn more about Fetal Ventriculomegaly at TriStar Centennial Parthenon Pavilion DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
Shuo - IACL
Muhan Shao, Shuo Han, Aaron Carass, Xiang Li, Ari M. Blitz, Jaehoon Shin, Jerry L. Prince, and Lotta M. Ellingsen. Brain ventricle parcellation using a deep neural network: Application to patients with ventriculomegaly. NeuroImage: Clinical, ...
If your baby is born prematurely, there are many worries that likely go through your mind. One of the things that can happen is bleeding on the brain. Read on to learn about this and what doctors can do help your baby.
Intraventricular hemorrhage | GreenMedInfo | Disease | Natural
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Trance) VA - A State of Sundays 095 - 2012, MP3, VBR kbps
Artist: VA Title: A State of Sundays 095 Genre: Trance Release date: 2012 Audio codec: MP3 Format: tracks Quality: VBR kbps Time: 10:03:28 Tracklist: Markus Schulz 01. Raneem - Airglow (Basil OGlue Remix) [Vibrate Sounds] 02. Radion 6 - Lost in Space (Original Mix) [Reset Recordings] 03. Skytech - Whats Wrong (Original Mix) [Coldharbour Recordings Red] 04.
Winds Of Torment (Fra) Delighting In Relentless Ignorance 2007 [email protected] Melodic Death Metal Torrent Downloads - download free...
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What is the Foramen of Monro?
The foramen of Monro is an opening that connects the left and right sides of the lateral ventricles in the brain. The purpose of...
Intraventricular Drug Delivery
Intraventricular drug delivery is the delivery of pain medication within the cerebrospinal fluid of the cistern (C1-2 vertebra) and intracranial ventricles.
STATdx - Intraventricular Calcification(s)
Developed by renowned radiologists in each specialty, STATdx provides comprehensive decision support you can rely on - Intraventricular Calcification(s)
A modified echocardiographic protocol with intrinsic plausibility control to determine intraventricular asynchrony based on TDI...
A modified echocardiographic protocol with intrinsic plausibility control to determine intraventricular asynchrony based on TDI and TSI. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
oligonucleotides antisense Protocols and Video...
Video articles in JoVE about oligonucleotides antisense include Direct Intraventricular Delivery of Drugs to the Rodent Central Nervous System.
Non-invasive intracranial pressure measurement methods
Cerebral ventricle. Michaeli  proposed that ICP be inferred from the magnitude and shape of pulsations of the third ... including cerebral Autoregulation and Cerebral Compliance).. Transcranial Doppler ultrasonography. The TCD measures the ... January 2003). "Adaptive noninvasive assessment of intracranial pressure and cerebral autoregulation". Stroke. 34 (1): 84-9. ... brain ventricles, and/or intracranial vessels). The common drawback of all these methods is that they measure only relative ...
Knock out mice with homozygous mutations have non-viable offspring with enlarged cerebral ventricles. A consanginous couple has ... Post mortum showed enlarged cerebral ventricles and contracted limbs. GRCm38: Ensembl release 89: ENSMUSG00000036333 - Ensembl ... Homozygous KIDINS220 loss-of-function variants in fetuses with cerebral ventriculomegaly and limb contractures. Hum Mol Genet ...
Route of administration
Intracerebroventricular (into the cerebral ventricles) administration into the ventricular system of the brain. One use is as a ... "A potential application for the intracerebral injection of drugs entrapped within liposomes in the treatment of human cerebral ...
In his book he described finding a large amount of fluid between cerebral ventricles. This fluid is known now to be ...
... cerebral ventricles, and spinal cord. Asymptomatic infections and calcified cysticerci probably will not require treatment. ...
CT scans have found that the cerebral ventricles expand as a function of age. More recent MRI studies have reported age-related ... Cognitive impairment has been attributed to oxidative stress, inflammatory reactions and changes in the cerebral ... and frontal cerebral cortex, decline with age. A decreased binding capacity of the 5-HT2 receptor in the frontal cortex was ... whereas white matter consists of tightly packed myelinated axons connecting the neurons of the cerebral cortex to each other ...
Leonardo da Vinci
He created models of the cerebral ventricles with the use of melted wax and constructed a glass aorta to observe the ... He made the observations that humours were not located in cerebral spaces or ventricles. He documented that the humours were ...
It is located in the posterior part of the third ventricle, overlying the cerebral aqueduct. In severe cases of hydrocephalus ...
In June 2020, Cunego was hospitalised due to ventriculitis, an infection of the cerebral ventricle. 1998 1st Overall Giro della ... "Damiano Cunego hospitalised after contracting brain ventricle infection". cyclingnews.com. 16 June 2020. Retrieved 18 June 2020 ...
Cerebral aqueduct. The cerebral aqueduct is the part of the ventricular system which links the third ventricle (rostally ... The cerebral aqueduct is the smallest ventricle in the ventricular system. It is located between the tectum and the tegmentum, ... The principle regions of the midbrain are the tectum, the cerebral aqueduct, tegmentum, and the basis pedunculi. Rostrally the ... The tegmentum is the portion of the midbrain ventral to the cerebral aqueduct, and is much larger in size than the tectum. It ...
"Deletion including the oligophrenin-1 gene associated with enlarged cerebral ventricles, cerebellar hypoplasia, seizures and ... A small cerebellum and large ventricles can be seen on brain imaging (MRI). Treatment is supportive and includes physical, ...
Ultrasonography demonstrated fetal hydrops, diaphragmatic hernia, and striking dilatation of the cerebral ventricles in both ... Progressive cerebral and brainstem atrophy was noted on serial MRIs made at 3 months and after 6 months of age. Van Hove et al ... cerebral ventricular dilation, camptodactyly, agenesis of sacrum, low-set ear. In a newborn boy thought to ...
... is a neurosurgical procedure that involves creating a hole (stoma) within a cerebral ventricle for drainage. It ... It is done by surgically penetrating the skull, dura mater, and brain such that the ventricle of the brain is accessed. When ... For example, a "third ventriculostomy" is a neurosurgical procedure that creates a hole in the floor of the third ventricle and ...
Additionally, blockage of ventricles could cause buildup of cerebral spinal fluid resulting in swelling around the tumor. The ... The cysts are benign tumors that usually appear in the anterior third ventricle. The cysts occur in the epithelium putting ... has still not been resolved as neural chimeras have been shown to circulate throughout the ventricles and incorporate into all ...
Also noticed were hemorrhages in the gray matter around the third and fourth ventricles and the cerebral aqueduct. Brain ... the walls of the 3rd ventricle, the floor of the 4th ventricle, the cerebellum, and the frontal lobe. In addition to the damage ...
History of neuroscience
He described in great detail the structure of the brainstem, the cerebellum, the ventricles, and the cerebral hemispheres. The ... Broca performed an autopsy and determined that the patient had a lesion in the frontal lobe in the left cerebral hemisphere. ... He was also the first person to associate mental deficits with deficits in the brain's middle ventricle or frontal lobe. ... Richard Caton presented his findings in 1875 about electrical phenomena of the cerebral hemispheres of rabbits and monkeys. In ...
Hereditary diffuse leukoencephalopathy with spheroids
In HDLS, there is enlargement of the lateral ventricles and marked thinning or weakening of cerebral white matter. The loss of ... is a rare adult onset autosomal dominant disorder characterized by cerebral white matter degeneration with demyelination and ...
CT will usually show distortion of third and lateral ventricles with displacement of anterior and middle cerebral arteries. ... but with a preference for the cerebral hemispheres; they occur usually in adults, and have an intrinsic tendency to progress to ...
Walker and Blackfan discovered where cerebrospinal fluid originated by tracking dye injected into the cerebral ventricle of a ...
"Inhibition of post-partum maternal behaviour in the rat by injecting an oxytocin antagonist into the cerebral ventricles". The ...
"Effects of some benzodiazepines on the acetylcholine release in the anterior horn of the lateral cerebral ventricle of the cat ...
... gray matter heterotopia is the presence of gray matter within the cerebral white matter or ventricles. Heterotopia within the ...
The cranial pia mater joins with the ependyma, which lines the cerebral ventricles to form choroid plexuses that produce ... This layer goes in between the cerebral gyri and cerebellar laminae, folding inward to create the tela chorioidea of the third ... It is absent only at the natural openings between the ventricles, the median aperture, and the lateral aperture. The pia firmly ... The CSF travels from the ventricles and cerebellum through three foramina in the brain, emptying into the cerebrum, and ending ...
Human brain development timeline
... third ventricles, cerebral aqueduct, and upper and lower parts of the fourth ventricle in adulthood originated from these ... These are the telencephalon, diencephalon, mesencephalon, metencephalon, and myelencephalon; the lateral ventricles, ...
The fluid-filled cerebral ventricles (lateral ventricles, third ventricle, cerebral aqueduct, fourth ventricle) are also ... Cerebral- and spinal white matter do not contain dendrites, neural cell bodies, or shorter axons, which can ... The total number of long range fibers within a cerebral hemisphere is 2% of the total number of cortico-cortical fibers (across ... "Cerebral Blood Flow, Blood Volume and Oxygen Utilization". Brain. 113: 27-47. doi:10.1093/brain/113.1.27. PMID 2302536. Marner ...
Traumagenic neurodevelopmental model of psychosis
... enlarged ventricles, cerebral atrophy and asymmetry). A criticism of the TN model is that most individuals who experience ...
... it extends between the layers of the tela choroidea of the third ventricle and contains the great cerebral vein and the pineal ... The superior cistern (cistern of great cerebral vein, quadrigeminal cistern) is a dilation as a subarachnoid cistern of the ... Other synonyms are cistern of great cerebral vein, quadrigeminal cistern, Bichat's canal, and Bichat's foramen. This article ...
... choroid plexus of the ventricles and post-cerebral rigidity, among other topics. She showed that meningitis in patients with ...
... then the cerebral aqueduct to the fourth ventricle. From the fourth ventricle, the fluid passes into the subarachnoid space ... The ventricles are a series of cavities filled with CSF. The majority of CSF is produced from within the two lateral ventricles ... CSF also serves a vital function in the cerebral autoregulation of cerebral blood flow. The CSF occupies the subarachnoid space ... As the forebrain develops, the neural cord within it becomes a ventricle, ultimately forming the lateral ventricles. Along the ...
Coronal section through anterior cornua of lateral ventricles. Horizontal section of left cerebral hemisphere. 3D view of the ... The cerebral cortex processing vestibular sensations extends into the insula, with small lesions in the anterior insular cortex ... The insular cortex (also insula and insular lobe) is a portion of the cerebral cortex folded deep within the lateral sulcus ( ... Cerebral Cortex. 23 (4): 833-846. doi:10.1093/cercor/bhs077. PMC 3657385. PMID 22473895. Taylor KS, Seminowicz DA, Davis KD ( ...
The systemic heart has muscular contractile walls and consists of a single ventricle and two atria, one for each side of the ... This causes death by respiratory failure leading to cerebral anoxia. No antidote is known, but if breathing can be kept going ...
The abnormalities seen in the SPECT images are very similar to those seen in people with cerebral vacuities and Creutzfeldt- ... Neuroimaging findings in an MRI include lesions in the periventricular white matter, as well as enlarged ventricles and ... Fallon BA, Keilp J, Prohovnik I, Heertum RV, Mann JJ (2003). "Regional cerebral blood flow and cognitive deficits in chronic ...
Brain metastasis in the right cerebral hemisphere from lung cancer, shown on magnetic resonance imaging. ... This fluid circulates in the narrow spaces between cells and through the cavities in the brain called ventricles, to nourish, ... Early imaging methods - invasive and sometimes dangerous - such as pneumoencephalography and cerebral angiography have been ... although glial cells outnumber neurons roughly 4 to 1 in the cerebral cortex. Glia come in several types, which perform a ...
High-altitude cerebral edema
CT scans of patients with HACE exhibited ventricle compression and low density in the cerebellum. Only a few autopsies have ... High-altitude cerebral oedema (HACO). High-altitude cerebral edema (HACE) is a medical condition in which the brain swells with ... If a lumbar puncture is performed, it will show normal cerebral spinal fluid and cell counts but an increase in pressure. In ... Wilson, Mark; Newman, Stanton; Imray, Chris (2009). "The Cerebral Effects of Ascent to High Altitudes". Lancet Neurology. 8 (2 ...
Brain-derived neurotrophic factor
"BDNF regulates reelin expression and Cajal-Retzius cell development in the cerebral cortex". Neuron. 21 (2): 305-15. doi: ... Infusion of BDNF into the lateral ventricles doubled the population of newborn neurons in the adult rat olfactory bulb and ... "Behaviorally-induced ultrastructural plasticity in the hippocampal region after cerebral ischemia". Brain Research. 997 (2): ... "Environmental enrichment induces synaptic structural modification after transient focal cerebral ischemia in rats". ...
নিতম্বাস্থি - উইকিপিডিয়া
মস্তিষ্ক গোলার্ধ (Cerebral hemisphere). *আন্তর মস্তিষ্ক (Diencephalon). *মস্তিষ্ককাণ্ড (Brain stem) *মধ্যমস্তিষ্ক ( ... নিলয় (Ventricle). *হৃৎকপাটিকা (Heart valve). *রক্ত (Blood). *রক্তবাহ (Blood vessel). *ধমনী (Artery) ...
When Aβ oligomers were injected into the cerebral ventricles of a mouse model of Alzheimer's, PRNP deletion did not offer ...
Moderator bands, full of purkinje fibers, are found in different locations in the left and right ventricles. These bands ... The morphology for heat exchange occurs via cerebral arteries and the ophthalmic rete, a network of arteries originating from ... The atria, ventricles, and septum are supplied of blood by this modality. The deep branches of the coronary arteries found ... Finally, they suggest that warm venous blood perfusion at the ophthalmic rete facilitates warming of cerebral blood that ...
癱瘓疾病（英语：Template:Cerebral palsy and other paralytic syndromes） ... 侧脑室（英语：Template:Lateral ventricles）. *基底核. *間腦 ...
Males have been found to have on average greater cerebral, cerebellar and cerebral cortical lobar volumes, except possibly left ... In addition, lateral ventricle volume appears to be mainly explained by environmental factors, suggesting such factors also ... Total cerebral and gray matter volumes peak during the ages from 10-20 years (earlier in girls than boys), whereas white matter ... In humans, the right cerebral hemisphere is typically larger than the left, whereas the cerebellar hemispheres are typically ...
Some examples of neurological damage include hypertensive encephalopathy, cerebral vascular accident/cerebral infarction, ... As the left ventricle becomes unable to compensate for an acute rise in systemic vascular resistance, left ventricular failure ... is a manifestation of the dysfunction of cerebral autoregulation. Cerebral autoregulation is the ability of the blood ... On the other hand, sudden or rapid rises in blood pressure may cause hyperperfusion and increased cerebral blood flow, causing ...
Cerebral contusionEdit. Main article: Cerebral contusion. Cerebral contusion is bruising of the brain tissue. The piamater is ... bleeding within the brain's ventricles (particularly of premature infants). Intra-axial hemorrhages are more dangerous and ... Main article: cerebral hemorrhage. Intra-axial hemorrhage is bleeding within the brain itself, or cerebral hemorrhage. This ... Complications may include cerebral edema and transtentorial herniation. The goal of treatment should be to treat the increased ...
The following conditions should also be excluded: DI, cerebral salt wasting, pseudohyponatraemia caused by hyperlipidemia or ... show a shrunken cortex and enlarged ventricles on an MRI scan, which makes differentiation between psychogenic and ... coma and cerebral oedema. It can also cause central pontine myelinolysis. Treatment for psychogenic polydipsia depends on ...
"Stroke: A Journal of Cerebral Circulation. 45 (2): 520-26. doi:10.1161/STROKEAHA.113.003433. PMID 24385275.. ... A heartbeat results when an electrical impulse from the atria passes through the atrioventricular (AV) node to the ventricles ... ventricles), thus restoring the normal heart rhythm. People with AF often undergo cardiac surgery for other underlying ... in the atria and ventricles of the heart. This remodeling leads to abnormally increased pressure in the left atrium, ...
... also observed that air introduced into the subarachnoid space via lumbar spinal puncture could enter the cerebral ventricles ... Uptake of SPECT agent is nearly 100% complete within 30 to 60 seconds, reflecting cerebral blood flow (CBF) at the time of ... In 1927 Egas Moniz introduced cerebral angiography, whereby both normal and abnormal blood vessels in and around the brain ... SPECT provides a "snapshot" of cerebral blood flow since scans can be acquired after seizure termination (so long as the ...
ಟೆಂಪ್ಲೇಟು:Central nervous system navs - ವಿಕಿಪೀಡಿಯ
These are geared towards lay readers, not readers who are technically proficient. Do not replace easy to understand lay variants (e.g. "smell") with difficult variants lay readers will not understand (e.g. "olfaction ...
... cerebral hematoma, cerebral bleed. CT scan of a spontaneous intracerebral bleed, leaking into the lateral ventricles. ... It accounts for 20% of all cases of cerebrovascular disease in the United States, behind cerebral thrombosis (40%) and cerebral ... "Journal of Cerebral Blood Flow & Metabolism. 30 (4): 689-702. doi:10.1038/jcbfm.2009.282. PMC 2949160. PMID 20087366. Archived ... Cerebral bleeding affects about 2.5 per 10,000 people each year. It occurs more often in males and older people. About 44 ...
失智症 - 维基百科，自由的百科全书
癱瘓疾病（英语：Template:Cerebral palsy and other paralytic syndromes） ... 侧脑室（英语：Template:Lateral ventricles）. *基底核. *間腦 ... 大脑中动脉综合征（英语：Middle cerebral artery syndrome） ... 大脑前动脉综合
... showing how their pulsation depends upon the contraction of the left ventricle, while the contraction of the right ventricle ... Descriptions of the event seem to show that he died of a cerebral haemorrhage from vessels long injured by gout: it is highly ... Whilst doing this, the physician reiterates the fact that these two ventricles move together almost simultaneously and not ... Galen believed that blood passed between the ventricles by means of invisible pores. According to Galen's views, the venous ...
Idiopathic intracranial hypertension
In IIH these scans typically appear to be normal, although small or slit-like ventricles, dilatation and buckling of the ... in phase contrast MRA studies have quantified cerebral blood flow (CBF) in vivo and suggests that CBF is abnormally elevated in ... These shunts are inserted in one of the lateral ventricles of the brain, usually by stereotactic surgery, and then connected ... An MR venogram is also performed in most cases to exclude the possibility of venous sinus stenosis/obstruction or cerebral ...
cerebral cortex development. • establishment of mitotic spindle orientation. • regulation of gene expression. • regulation of ... MCPH1 is expressed in the fetal brain, in the developing forebrain, and on the walls of the lateral ventricles. Cells of this ... area divide, producing neurons that migrate to eventually form the cerebral cortex. ...
The most inferior of the spinal nerves, the coccygeal nerve leaves the spinal cord at the level of the conus medullaris via respective vertebrae through their intervertebral foramina, superior to the filum terminale. However, adhering to the outer surface of the filum terminale are a few strands of nerve fibres which probably represent rudimentary second and third coccygeal nerves. Furthermore, the central canal of the spinal cord extends 5 to 6 cm beyond the conus medullaris, downward into the filum terminale. ...
Wikipedia:WikiProject Missing encyclopedic articles/Missing diseases/7
Keratosis follicularis dwarfism cerebral atrophy. *Keratosis palmoplantaris adenocarcinoma of the colon. *Keratosis ... Left ventricle-aorta tunnel. *Leg absence deformity cataract. *Lehman syndrome. *Leichtman Wood Rohn syndrome ...
Cerebral edema is extracellular fluid accumulation in the brain. It can occur in toxic or abnormal metabolic states and ... This is usually due to failure of the left ventricle of the heart. It can also occur in altitude sickness or on inhalation of ...
The right ventricle is equal in size to that of the left ventricle and contains roughly 85 millilitres (3 imp ... The left ventricle is thicker and more muscular than the right ventricle because it pumps blood at a higher pressure. ... Ventricles have thicker walls than atria and generate higher blood pressures. The physiological load on the ventricles ... During diastole, the ventricles relax and fill with blood again. The left ventricle receives oxygenated blood from the left ...
Blood velocity can be measured in various blood vessels, such as middle cerebral artery or descending aorta, by relatively ... outlining thereby the ventricles of a human brain. Ultrasonic energy was first applied to the human body for medical ... such as in echocardiography to improve delineation of left ventricle for visually checking contractibility of heart after a ... Doppler is frequently used by neuro-anesthesiologists for obtaining information about flow-velocity in the basal cerebral ...
In each hemisphere of the mammalian brain the insular cortex (also insula and insular lobe) is a portion of the cerebral cortex ... The cerebral cortex processing vestibular sensations extends into the insula, with small lesions in the anterior insular ... "Individual patterns of functional reorganization in the human cerebral cortex after capsular infarction". Annals of Neurology. ...
Terri Schiavo case
Throughout the cerebral cortex, the large pyramidal neurons that comprise some 70% of cortical cells - critical to the ... Quote: "She had developed hydrocephalus ex vacuo, a condition marked by enlarged ventricles filled with cerebrospinal fluid, ... In preparation for the trial, a new computed axial tomography scan (CAT scan) was performed, which showed severe cerebral ... Microscopic examination revealed extensive damage to nearly all brain regions, including the cerebral cortex, the thalamus, the ...
Definition of Ventricle, cerebral
Ventricle, cerebral: One of a system of four communicating cavities within the brain that are continuous with the central canal ... They include two lateral ventricles in the cerebral hemispheres, each consisting of a triangular central body and four horns. ... The lateral ventricles communicate with the third ventricle through an opening called the interventricular foramen. The third ... In front, the third ventricle communicates with the lateral ventricles, and in back it communicates with the aqueduct of the ...
Massively dilated Ventricles and severe brain damage - Cerebral Palsy Message Board - HealthBoards
Cerebral Palsy Message Board HealthBoards , Brain & Nerves , Cerebral Palsy > Massively dilated Ventricles and severe brain ... Massively dilated Ventricles and severe brain damage My daughter Venya is 2 and half years old now. When she was just 15 days ... enlarged ventricles in head StaceySarah123. Brain & Nervous System Disorders. 1. 10-21-2008 07:14 PM. ... Brain Shunt Surgery for Hydrocephalus (Enlarged Ventricles Caused by Excess Fluid) tr3. Brain & Nervous System Disorders. 14. ...
Decreased Volume of the Cerebral Ventricles on CT Images in Gilles de la Tourette's Syndrome
Cerebral Pouches? Ventricles?
1. Cerebral pouches - which brought up some very strange links - and cerebral ventricles. Are they the same? Or is the ... 1. Cerebral pouches - which brought up some very strange links - and cerebral ventricles. Are they the same? Or is the ... The cerebral ventricles, conversely, are present in the adult brain.. 2. On the Wiki page (above), about 1/3 of the way down, ... Re: Cerebral Pouches? Ventricles?. by vivian maxine on August 17th, 2016, 8:27 am ...
Ventricle of cerebral hemisphere - Biology-Online Dictionary | Biology-Online Dictionary
ventricle of cerebral hemisphere --, lateral ventricle A cavity shaped somewhat like a horseshoe in conformity with the general ... each lateral ventricle communicates with the third ventricle through the interventricular foramen of Monro, and expands from ... The large choroid plexus of the lateral ventricle invades the cella media and the inferior horn (but not the anterior and ... Retrieved from "https://www.biology-online.org/dictionary/index.php?title=Ventricle_of_cerebral_hemisphere&oldid=47830" ...
Relationship of cerebral blood flow to aortic-to-pulmonary collateral/shunt flow in single ventricles | Heart
Relationship of cerebral blood flow to aortic-to-pulmonary collateral/shunt flow in single ventricles ... Relationship of cerebral blood flow to aortic-to-pulmonary collateral/shunt flow in single ventricles ... Conclusions There is a strong inverse relationship between CBF and APC/shunt flow in patients with single ventricle throughout ... Objective Patients with single ventricle can develop aortic-to-pulmonary collaterals (APCs). Along with systemic-to-pulmonary ...
ICD-10-PCS Code 00W63YZ - Revision of Other Device in Cerebral Ventricle, Percutaneous Approach - Codify by AAPC
ICD-10-PCS code 00W63YZ for Revision of Other Device in Cerebral Ventricle, Percutaneous Approach is a medical classification ... Left lateral ventricle , Right lateral ventricle , Third ventricle","3")>Cerebral Ventricle. Definition: Entry, by puncture or ... Revision of Other Device in Cerebral Ventricle, Percutaneous Approach 00W63YZ. ICD-10-PCS code 00W63YZ for Revision of Other ... Device in Cerebral Ventricle, Percutaneous Approach is a medical classification as listed by CMS under Central Nervous System ...
ICD-10-PCS Code 00163J5 - Bypass Cerebral Ventricle to Intestine with Synthetic Substitute, Percutaneous Approach - Codify by...
Compartmentalization of the cerebral ventricles as a sequela of neonatal meningitis in: Journal of Neurosurgery Volume 52 Issue...
Neurotoxic potential of gadodiamide after injection into the lateral cerebral ventricle of rats. | American Journal of...
Neurotoxic potential of gadodiamide after injection into the lateral cerebral ventricle of rats.. D E Ray, J L Holton, C C ... Neurotoxic potential of gadodiamide after injection into the lateral cerebral ventricle of rats. ... Neurotoxic potential of gadodiamide after injection into the lateral cerebral ventricle of rats. ... Neurotoxic potential of gadodiamide after injection into the lateral cerebral ventricle of rats. ...
Demonstration of Cerebral Venous Variations in the Region of the Third Ventricle on Phase-Sensitive Imaging | American Journal...
Cerebral venous variations in the region of the third ventricle on PSI. Abbreviations are the same as in Fig 1. A, Type IA: the ... Demonstration of Cerebral Venous Variations in the Region of the Third Ventricle on Phase-Sensitive Imaging. S. Fujii, Y. ... Demonstration of Cerebral Venous Variations in the Region of the Third Ventricle on Phase-Sensitive Imaging ... Figure 3 shows representative cases of the 4 types of cerebral venous variation in the region of the third ventricle. Data ...
Artificial intelligence for automatic cerebral ventricle segmentation and volume calculation: a clinical tool for the...
Qiu W, Yuan J, Rajchl M, 3D MR ventricle segmentation in pre-term infants with post-hemorrhagic ventricle dilatation (PHVD) ... Qiu W, Yuan J, Rajchl M, 3D MR ventricle segmentation in pre-term infants with post-hemorrhagic ventricle dilatation (PHVD) ... Walter Dandy reported the first technique for visualizing the cerebral ventricles.1 Since then, imaging of the ventricles on CT ... Manual segmentation of the cerebral ventricles was performed on all axial slices by a neurosurgery resident (J.L.Q.) and a ...
"Quantification of Cerebral Ventricle Volume Change of Preterm Neonates" by Yimin Chen, Jessica Kishimoto et al.
In this work, we report on the development and application of a method used to analyze local surface change of the ventricles ... The distance between each pair of corresponding points served as an estimate of local surface change of the brain ventricle at ... The measurements of local surface change were then superimposed on the ventricle surface to produce the 3D local surface change ... 3D ultrasound (US) has been used to monitor the ventricle volume as a biomarker for ventricular dilation. However, volumetric ...
Survival and proliferation of nonneural tissues, with obstruction of cerebral ventricles, in a parkinsonian patient treated...
Survival and proliferation of nonneural tissues, with obstruction of cerebral ventricles, in a parkinsonian patient treated ... Survival and proliferation of nonneural tissues, with obstruction of cerebral ventricles, in a parkinsonian patient treated ... the left lateral and fourth ventricles were filled completely by this proliferated tissue. ...
Ocular silicone oil in the lateral cerebral ventricle<...
Campbell, G., Milbourne, S., Salman, U. A., & Khan, M. A. (2013). Ocular silicone oil in the lateral cerebral ventricle. ... Campbell, G, Milbourne, S, Salman, UA & Khan, MA 2013, Ocular silicone oil in the lateral cerebral ventricle, Journal of ... Ocular silicone oil in the lateral cerebral ventricle. / Campbell, Garth; Milbourne, Shannon; Salman, Umber A.; Khan, Majid A. ... Fingerprint Dive into the research topics of Ocular silicone oil in the lateral cerebral ventricle. Together they form a ...
Non-invasive intracranial pressure measurement methods - Wikipedia
Cerebral ventricle. Michaeli  proposed that ICP be inferred from the magnitude and shape of pulsations of the third ... including cerebral Autoregulation and Cerebral Compliance).. Transcranial Doppler ultrasonography. The TCD measures the ... January 2003). "Adaptive noninvasive assessment of intracranial pressure and cerebral autoregulation". Stroke. 34 (1): 84-9. ... brain ventricles, and/or intracranial vessels). The common drawback of all these methods is that they measure only relative ...
Cerebral Ventricles And Vessels - Anatomy Diagram Charts
Cerebral Ventricles (see Brain Ventricles) - Explaining Medicine
Cerebral Ventricles)A series of interconnected, fluid-filled found within the . These cavities are the ventricles of the brain ... Cerebral Ventricles (see Brain Ventricles). Brain Ventricles (Cerebral Ventricles). A series of interconnected, fluid-filled ... Cerebral Ventricles (see Brain Ventricles) was last modified: June 24th, 2016 by explainingmedicine ... found within the . These cavities are the ventricles of the brain, and the fluid is . ...
Proximal fetal cerebral ventricle: Description of US technique and initial results - Fingerprint - UC Davis
Flat-panel detector volumetric CT for visualization of subarachnoid hemorrhage and ventricles: preliminary results compared to...
Additionally, reliable evaluation of ventricle width is feasible. However, there are limitations with regard to the visibility ... Methods: Included in the study were 22 patients with an acutely ruptured cerebral aneurysm who received VCT during coil ... The width of the ventricles measured in terms of the Evans Index showed excellent concordance between the modalities (r=0.81 vs ... Additionally, reliable evaluation of ventricle width is feasible. However, there are limitations with regard to the visibility ...
ISMRM 2014) Relationship between Cerebral Ventricles dilatation and Cerebrospinal Fluid oscillations
Relationship between Cerebral Ventricles dilatation and Cerebrospinal Fluid oscillations. Bader Chaarani 1 , Cyrille Capel 2 , ... acquisition adult altered amplitude aqueduct arachnoid aspects axial brain cardiac cerebral cervical chronic common complex ... software space still stroke studies suffering system table third unclear underwent variation vascular ventricle ventricles ... the aqueductal and cerebral levels in 45 neurodegenerative diseases. Results show that cerebrospinal fluid flow does not depend ...
Centralis neurocytoma: az agykamrák ritka daganata.<...
... a rare tumor of the cerebral ventricles. Together they form a unique fingerprint. * Cerebral Ventricle Neoplasms Medicine & ... The underlying lesion was a hemorrhagic tumor located in the left lateral ventricle. On histological examination, the ... The underlying lesion was a hemorrhagic tumor located in the left lateral ventricle. On histological examination, the ... The underlying lesion was a hemorrhagic tumor located in the left lateral ventricle. On histological examination, the ...
Survival and proliferation of nonneural tissues, with obstruction of cerebral ventricles, in a parkinsonian patient treated...
Studies on cinchocaine and lidocaine administered into cerebral ventricles of conscious and anaesthetized dogs. | IMSEAR
Full text: Available Index: IMSEAR (South-East Asia) Main subject: Quinolines / Female / Male / Cerebral Ventricles / Dogs / ... Full text: Available Index: IMSEAR (South-East Asia) Main subject: Quinolines / Female / Male / Cerebral Ventricles / Dogs / ... Anesthetics, Local/pharmacology , Animals , Cerebral Ventricles/drug effects , Dogs , Female , Injections , Lidocaine/ ... Studies on cinchocaine and lidocaine administered into cerebral ventricles of conscious and anaesthetized dogs. ...
Computational Model of the Cerebral Ventricles in Hydrocephalus | Journal of Biomechanical Engineering | ASME Digital Collection
Computational Model of the Cerebral Ventricles in Hydrocephalus Shaokoon Cheng Shaokoon Cheng ... Cheng, S., and Bilston, L. E. (March 24, 2010). "Computational Model of the Cerebral Ventricles in Hydrocephalus." ASME. J ... In this study, a three-dimensional (3D) finite element model of the cerebral ventricles during hydrocephalus is presented. ... This may not be adequate as the geometry of the cerebral ventricles is unique. ...
Apical Aneurysm - Right Ventricle & Cerebral Embolism & Rheumatic Heart Disease<...
Cerebral Embolism, Rheumatic Heart Disease Symptom Checker: Possible causes include Atrial Septal Defect, Cardiomyopathy, ... 13 Possible Causes for Apical Aneurysm - Right Ventricle, Cerebral Embolism, Rheumatic Heart Disease * Atrial Septal Defect ... Differential diagnoses, possible causes and diseases for Apical Aneurysm - Right Ventricle, Cerebral Embolism, Rheumatic Heart ... ICD implantable cardioverter defibrillator; LA left atrium; LV left ventricle; RV right ventricle; SD sudden death; VT ...
vesicles to ventricles Flashcards by Tiffany Pointon | Brainscape
Study vesicles to ventricles flashcards from Tiffany Pointon ... third ventricle > cerebral aquaduct > fourth ventricle > exit ... third ventricle, fourth ventricle, interventricular foramen, cerebral aqueduct, cisterna magna, interpeduncular cistern. ... 1. anterior cerebral artery: anterior two-thirds of the medial face of the cerebral hemisphere, and the orbital cortex. 2. ... vesicles to ventricles Flashcards Preview Neuro unit 1 , vesicles to ventricles , Flashcards ...
Computed tomography of the trapped fourth ventricle.
Computed tomography reveals cystic dilatation of the fourth ventricle and hydrocephalus s ... A dilated fourth ventricle due to outlet obstruction is a clinical-radiologic entity with symptoms similar to those of a ... Cerebral Ventricles. Cerebral Ventriculography*. Child. Dilatation, Pathologic / radiography. Female. Humans. Hydrocephalus / ... A dilated fourth ventricle due to outlet obstruction is a clinical-radiologic entity with symptoms similar to those of a ...
Enlarged lateral ventricles (LV) and reduced cerebral cortex (Ctx) in Disc1tr transgenic (Tg) mice. WT (A) and Tg (B) brain ... Dilated lateral ventricles and reduced cerebral cortex in Disc1tr transgenic mice. Schizophrenic symptoms usually begin in late ... 3A,B). Sizes of the cerebral cortex and corpus callosum were quantified. The transgenic lateral ventricles were found to be ... Disc1tr transgenic mice display enlarged lateral ventricles, reduced cerebral cortex, partial agenesis of the corpus callosum, ...
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- In front, the third ventricle communicates with the lateral ventricles, and in back it communicates with the aqueduct of the midbrain (also known as the aqueduct of Sylvius). (medicinenet.com)
- The fourth ventricle, which is the lowest of the four ventricles of the brain, extends from the aqueduct of the midbrain to the central canal of the upper end of the spinal cord, with which it communicates, through the two foramina of Luschka and the foramen of Magendie. (medicinenet.com)
- If there is actual obliteration of the aqueduct, the fourth ventricle must be shunted directly. (biomedsearch.com)
- The neural canal that does not expand and remains the same at the level of the midbrain superior to the fourth ventricle forms the cerebral aqueduct. (wikipedia.org)
- One of the most common causes is aqueductal stenosis, a narrowing of the aqueduct of Sylvius, a small passage between the third and fourth ventricles in the middle of the brain. (hopkinsmedicine.org)
- This leads down to the fourth ventricle (lower right) via a channel, the cerebral aqueduct. (sciencephoto.com)
- MRIs also showed increased fluid volumes inside the cerebral aqueduct, a slim channel connecting the brain's ventricles. (upi.com)
- 1. anterior cerebral artery: anterior two-thirds of the medial face of the cerebral hemisphere, and the orbital cortex. (brainscape.com)
- Penetrating branches of middle cerebral artery supply deep cerebral cortex. (brainscape.com)
- Disc1 tr transgenic mice display enlarged lateral ventricles, reduced cerebral cortex, partial agenesis of the corpus callosum, and thinning of layers II/III with reduced neural proliferation at midneurogenesis. (jneurosci.org)
- Which of the following is not a lobe of the cerebral cortex? (weegy.com)
- To observe the effect of electroacupuncture (EA) and acupuncture (A) on the proliferation of stem cells in the subependymal zone (SPZ) of the lateral ventricle and the frontal lobe cortex in hyperlipemia(HL) combined with cerebral ischemia (CI) rats. (unboundmedicine.com)
- they are usually referred to by their position relative to the body (anterior, posterior, or inferior), or sometimes by the lobe of the cerebral cortex into which they extend. (wikipedia.org)
- The remainder of the medial edge of the ventricle is directly in contact with white matter of the cortex of the occipital lobe. (wikipedia.org)
- Rakic has spent most of his career investigating the development of the cerebral cortex of man and other mammals, and it is for his outstanding contribution to this area of research that he has been awarded the Kavli Prize for Neuroscience. (scienceblogs.com)
- More than 100 years ago, the German neurologist Korbinian Brodmann carried out a comparative study of the cerebral cortex of mammals. (scienceblogs.com)
- Imaging evaluation of the cerebral ventricles is important for clinical decision-making in pediatric hydrocephalus. (thejns.org)
- Computed tomography reveals cystic dilatation of the fourth ventricle and hydrocephalus supratentorially. (biomedsearch.com)
- Computed tomography and magnetic resonance imaging of the brain revealed a slightly enhanced tumor in the fourth ventricle, with obstructive hydrocephalus. (nih.gov)
- In this study, a three-dimensional (3D) finite element model of the cerebral ventricles during hydrocephalus is presented. (asme.org)
- Results from this model show that during hydrocephalus, the periventricular regions experience the highest stress, and stress magnitude is approximately 80 times higher than the cerebral mantle. (asme.org)
- If its production is bigger than reabsorption or its circulation is blocked - the enlargement of the ventricles may appear and cause a hydrocephalus . (wikipedia.org)
- Hydrocephalus is a condition characterized by an abnormal accumulation of cerebrospinal fluid (CSF) within the ventricles of the brain. (hopkinsmedicine.org)
- When the circulatory path of the CSF is blocked, fluid begins to accumulate, causing the ventricles to enlarge and the pressure inside the head to increase, resulting in hydrocephalus. (hopkinsmedicine.org)
- She consulted Abhay Moghekar at the Johns Hopkins Cerebral Fluid Center , where she learned she had normal pressure hydrocephalus and underwent successful treatment. (hopkinsmedicine.org)
- Communicating hydrocephalus occurs when the flow of CSF is blocked after it exits the ventricles. (hopkinsmedicine.org)
- Non-communicating hydrocephalus - also called obstructive hydrocephalus - occurs when the flow of CSF is blocked along one or more of the narrow passages connecting the ventricles. (hopkinsmedicine.org)
- A baby with severe IVH may develop hydrocephalus , a buildup of extra fluid in the brain's ventricles. (kidshealth.org)
- hydrocephalus , an abnormal accumulation of fluid in the ventricles. (healthline.com)
- Under normal conditions on Earth, patients with a condition known as hydrocephalus, characterized by abnormally enlarged ventricles, report symptoms of dizziness, dementia and bladder control issues. (upi.com)
- If we can better understand the mechanisms that cause ventricles to enlarge in astronauts and develop suitable countermeasures, then maybe some of these discoveries could benefit patients with normal pressure hydrocephalus and other related conditions," Dr. Kramer said. (upi.com)
- Neoplasms located in the brain ventricles, including the two lateral, the third, and the fourth ventricle. (bioportfolio.com)
- 2. middle cerebral artery: lateral face of the cerebrum including frontal, parietal and temporal lobes. (brainscape.com)
- Pulsatility indices (PI) were recorded for the middle cerebral artery (MCA) and umbilical artery (UA) in 87 fetuses (209 studies) with HLHS, 29 fetuses (82 studies) with SVrp, and 104 age-matched normal control fetuses (104 studies). (ahajournals.org)
- HL model was established by feeding the animals with high fat forage for 6 weeks and CI model was established by FeCl3-induced occlusion of the unilateral middle cerebral artery. (unboundmedicine.com)
- Neurotoxic potential of gadodiamide after injection into the lateral cerebral ventricle of rats. (ajnr.org)
- Limited distribution of pertussis toxin in rat brain after injection into the lateral cerebral ventricles. (semanticscholar.org)
- The CHF rabbits received infusion of vehicle, SIM, or SIM + N ω -nitro- l -arginine methyl ester into the lateral cerebral ventricle via osmotic minipump for 7 days. (aspetjournals.org)
- Internal carotid artery: anterior brain (entire cerebral hemisphere except medial part of occipital lobeand interior part of temporal lobe. (brainscape.com)
- Each cerebral hemisphere contains a lateral ventricle, known as the left or right ventricle, respectively. (wikipedia.org)
- Anterior portion of each cerebral hemisphere. (slideshare.net)
- The curved lateral ventricles (one seen) lie on either side of the brain, one in each cerebral hemisphere. (sciencephoto.com)
- When implanted intracranially at distant sites from the tumor (e.g., into normal tissue, into the contralateral hemisphere, or into the cerebral ventricles), the donor cells migrate through normal tissue targeting the tumor cells (including human glioblastomas). (pnas.org)
- They include two lateral ventricles in the cerebral hemispheres, each consisting of a triangular central body and four horns. (medicinenet.com)
- The lateral ventricles are in the cerebral hemispheres. (psyweb.com)
- Cerebellar hemispheres, brainstem, aquaduct of sylvius and fourth ventricle are normal. (medhelp.org)
- Major tract of axons that functionally interconnects right and left cerebral hemispheres. (slideshare.net)
- Brainstem , area at the base of the brain that lies between the deep structures of the cerebral hemispheres and the cervical spinal cord . (britannica.com)
- Apical four-chamber view in transthoracic echocardiography, showing the right atrial appendage aneurysm (A). Right atrium (B) and right ventricle (C) size were normal. (symptoma.com)
- Cardiac magnetic resonance images revealed a thin-walled, apical aneurysm of right ventricle with multiple septations and marked obliteration of left ventricular apex. (symptoma.com)
- In this condition, a reentrant circuit is formed around the characteristic fibro-fatty tissue that has replaced the right ventricle . (symptoma.com)
- In addition, 30 sides in 15 patients were excluded because their images could not be evaluated due to susceptibility artifacts caused by an intraventricular or basal ganglion hemorrhage around the third ventricle. (ajnr.org)
- These are the first reported cases of the acute use of intraventricular tPA after Guglielmi detachable coiling treatment for ruptured cerebral aneurysm. (researchwithrutgers.com)
- An intraventricular hemorrhage (in-treh-ven-TRIK-yeh-ler HEM-er-idge) is bleeding in and around the brain's ventricles. (kidshealth.org)
- Dilation of the cerebral ventricles is a common condition in preterm neonates with intraventricular hemorrhage (IVH). (spie.org)
- Pathology confirmed this lesion to be an intraventricular epidermoid within the lateral ventricles (Figure 5). (appliedradiology.com)
- 1% incidence of an intraventricular epidermoid within the lateral ventricle. (appliedradiology.com)
- Intraventricular hemorrhage (IVH) is bleeding inside or around the ventricles in the brain. (rochester.edu)
- To investigate whether cortical expansion in primates reflects modification of cell-cycle kinetics, we determined cell-cycle length during neurogenesis in the proliferative cerebral ventricular zone of fetal rhesus monkeys, by using cumulative S-phase labeling with bromodeoxyuridine. (pnas.org)
- Within the single ventricle population, variability in anatomy influences fetal cerebral blood flow patterns. (ahajournals.org)
- Objective Patients with single ventricle can develop aortic-to-pulmonary collaterals (APCs). (bmj.com)
- This study investigated the relationship between CBF and APC flow on room air and in hypercarbia, which increases CBF in patients with single ventricle. (bmj.com)
- Conclusions There is a strong inverse relationship between CBF and APC/shunt flow in patients with single ventricle throughout surgical reconstruction on room air and in hypercarbia independent of other factors. (bmj.com)
- Whether these findings are also present in other forms of complex single ventricle in which there is unobstructed aortic flow but reduced pulmonary blood flow (SVrp), and the trends of these alterations over the course of gestation, are not known. (ahajournals.org)
- To compare cerebral blood flow patterns in the fetus with single ventricle based on (1) obstruction to aortic flow (HLHS) or (2) unobstructed aortic flow but obstructed pulmonic flow (SVrp), and to assess for trends during gestation. (ahajournals.org)
- Included in the study were 22 patients with an acutely ruptured cerebral aneurysm who received VCT during coil embolization. (nih.gov)
- [em-consulte.com] Aneurysm of the interauricular septum revealed by a cerebral embolism . (symptoma.com)
- A sinus of Valsalva aneurysm is a potential site of thrombus formation which may embolize to the systemic and cerebral circulation as well as the coronary [elynsgroup.com] We are reporting a twelve year old child with hyperdynamic circulation being diagnosed and treated as Rheumatic heart disease . (symptoma.com)
- Both patients had experienced a ruptured cerebral aneurysm and were initially moribund. (researchwithrutgers.com)
- What is a cerebral aneurysm? (rochester.edu)
- A cerebral aneurysm is a bulge in a weak area of the wall of a brain artery. (rochester.edu)
- A cerebral aneurysm more often happens in an artery under the front part of the brain. (rochester.edu)
- This is the most common type of cerebral aneurysm. (rochester.edu)
- Who is at risk for a cerebral aneurysm? (rochester.edu)
- What are the symptoms of a cerebral aneurysm? (rochester.edu)
- You may not know you have a cerebral aneurysm until it tears (ruptures). (rochester.edu)
- METHODS Rats, surgically prepared with a lateral ventricular cannula, were administered a slow injection at 2 microL/min of gadodiamide into the lateral ventricle, and behavioral and neuropathologic changes were noted. (ajnr.org)
- EA can upregulate Nestin and PCNA expression of the dorsolateral extension and the wall of the lateral ventricle of the brain on the ischemic side in rats with CI, and with HL+CI, which may contribute to its effects in promoting the proliferation and migration of neural stem cells in the brain. (unboundmedicine.com)
- METHODS: Male Wistar Kyoto (WKY) rats and spontaneously hypertensive rats (SH) (16 weeks old) were implanted with a stainless steel guide cannula leading into the fourth cerebral ventricle (4th V). The femoral artery and vein were cannulated for arterial pressure and heart rate measurement and drug infusion, respectively. (unifesp.br)
- Leptin (1 or 3.5 μg/2 μl) or saline (2 μl) was administered into the third cerebral ventricle of age- and weight-matched male and female rats. (diabetesjournals.org)
- To know this, the effects of an increase in methylation in the brain were studied by injecting SAM into the lateral ventricle of rats. (bio.net)
- To further study the effects of methylation, SAM was injected into the lateral ventricle of rats. (bio.net)
- The large choroid plexus of the lateral ventricle invades the cella media and the inferior horn (but not the anterior and posterior horn) from the medial side. (biology-online.org)
- In each case, the body of one or both lateral ventricles was completely divided by a membrane posterior to the foramen of Monro. (thejns.org)
- 1. posterior cerebral arteries (medial face of occipital lobe and inferior surface of temporal lobe). (brainscape.com)
- A dilated fourth ventricle due to outlet obstruction is a clinical-radiologic entity with symptoms similar to those of a posterior fossa space-occupying lesion. (biomedsearch.com)
- The posterior horn of lateral ventricle or occipital horn , passes into the occipital lobe . (wikipedia.org)
- The body of the lateral ventricle is the central portion, just posterior to the frontal horn. (wikipedia.org)
- The boundary facing exterior to the ventricle curvature is formed by the corpus callosum - the floor at the limit of the ventricle is the upper surface of the rostrum (the reflected portion of the corpus callosum), while nearer the body of the ventricle, the roof consists of the posterior surface of the genu . (wikipedia.org)
- The remaining boundary - that facing interior to the ventricle curvature - comprises the posterior edge of the caudate nucleus . (wikipedia.org)
- The posterior horn of lateral ventricle , or occipital horn , impinges into the occipital lobe in a posterior direction, initially laterally but subsequently curving medially and lilting inferiorly on the lateral side. (wikipedia.org)
- The patient was then transferred to a tertiary pediatric hospital, where a brain MRI demonstrated a large, lobulated and septated T2 hyperintense mass within the posterior bodies of the lateral ventricles (Figure 2). (appliedradiology.com)
- Each lateral ventricle resembles a C-shaped structure that begins at an inferior horn in the temporal lobe, travels through a body in the parietal lobe and frontal lobe, and ultimately terminates at the interventricular foramina where each lateral ventricle connects to the single, central third ventricle . (wikipedia.org)
- The anterior horn of lateral ventricle or frontal horn , passes forward and to the side, with a slight inclination downward, from the interventricular foramen into the frontal lobe , and curves around the front of the caudate nucleus . (wikipedia.org)
- This portion of the lateral ventricle impinges on the frontal lobe , passing anteriorly and laterally, with slight inclination inferiorly. (wikipedia.org)
- 3D ultrasound (US) has been used to monitor the ventricle volume as a biomarker for ventricular dilation. (uwo.ca)
- The measurements of local surface change were then superimposed on the ventricle surface to produce the 3D local surface change map that provide information on the spatio-temporal dilation pattern of brain ventricles following IVH. (uwo.ca)
- This post hemorrhagic ventricle dilation (PHVD) can lead to lifelong neurological impairment through ischemic injury due to increased intracranial pressure (ICP). (spie.org)
- evidenced by the dilation of the cerebral ventricle. (bio.net)
- The main part of the Fornix forms the next narrow portion of the lateral boundary, which is completed medially by a choroid plexus , which serves both ventricles. (wikipedia.org)
- The olfactory bulb of the sheep brain is hollow, the cavity (olfactory ventricle or rhinocele) is connected to the anterior horn of the lateral ventricle by a narrow channel and contains cerebrospinal fluid (c.s.f. (biomedsearch.com)
- Ependyma cover the inside of the lateral ventricles and are epithelial cells . (wikipedia.org)
Filled with cerebral spina2
- An encoder-decoder convolutional neural network architecture, in which T2-weighted MR images were used as input, automatically delineated the ventricles and output volumetric measurements. (thejns.org)
- The lateral ventricles, similarly to other parts of the ventricular system of the brain, develop from the central canal of the neural tube. (wikipedia.org)
- In mammals, including primates, neocortical neurons are generated during a restricted period of early ontogeny from the cerebral ventricular zone (VZ), a primitive epithelial sheet of dividing neural progenitor cells lining the cerebral ventricles. (pnas.org)
- The myelomeningocele is a saccular protrusion containing a neural placode bathed in cerebral spinal fluid (CSF), as shown below. (medscape.com)
- It is separated from the anterior horn of the other lateral ventricle by a thin neural sheet - septum pellucidum , which thus forms its medial boundary. (wikipedia.org)
- During neural development, vast numbers of immature nerve cells (progenitors) are generated by cell division at the ventricular zone (VZ), a specialized epithelial tissue that lines the cerebral ventricles. (scienceblogs.com)
Injected into the lateral1
- Bligh , J.: Effects on temperature of monoamines injected into the lateral ventricles of sheep. (springer.com)
- The courses of the anterior septal vein (ASV), thalamostriate vein, and internal cerebral vein (ICV) were evaluated. (ajnr.org)
- The anterior horn of lateral ventricle or frontal horn , is the portion which connects to the 3rd ventricle, via the interventricular foramen . (wikipedia.org)
- The body of the lateral ventricle is the central portion, between the anterior horn and the trigone. (wikipedia.org)
Ventricular system of the brain1
- Intracerebroventricular (into the cerebral ventricles) administration into the ventricular system of the brain. (wikipedia.org)
- In a review of 48 cases of an abnormally enlarged fourth ventricle demonstrated on CT, six were found to have a trapped fourth ventricle. (biomedsearch.com)
- Cerebral angiography initially played the dominant role in the evaluation of cerebral venous anatomy in patients with brain tumors, but its role is now greatly reduced following advances in tomographic imaging. (ajnr.org)
Cerebrospinal fluid flow1
- In this work, we study the relationship between ventricular dilatation and cerebrospinal fluid flow at the aqueductal and cerebral levels in 45 neurodegenerative diseases. (ismrm.org)
- abstract = "Aspergillosis of the cerebral ventricles developed in a 36-year-old heroin abuser who died during the sixth week of illness. (elsevier.com)
- The Meninges accurately accommodate the cerebral circulation (licensed separately) including the Superior Sagittal Sinus and the Transverse Sinus. (3dscience.com)
- The underlying lesion was a hemorrhagic tumor located in the left lateral ventricle. (elsevier.com)
- the left lateral and fourth ventricles were filled completely by this proliferated tissue. (neurology.org)
- Computed tomography of the trapped fourth ventricle. (biomedsearch.com)
- Frequently the symptoms resolve completely and the fourth ventricle returns to normal following lateral ventricular shunting. (biomedsearch.com)
- While the exact mechanism by which the fourth ventricle becomes trapped is not fully known, outlet obstruction must be present. (biomedsearch.com)
- Primary origins in the fourth ventricle are very rare. (nih.gov)
- We report a case of a fourth ventricle CN in a 35-year-old male patient with the initial symptoms of progressive headaches and blurred vision for more than 2 months. (nih.gov)
- CNs located in the fourth ventricle are extremely rare. (nih.gov)
- The cella media is the central part of the lateral ventricle. (wikipedia.org)
- Silicone oil used for endotamponade of retinal detachment may migrate into the subarachnoid space of the brain, including the cerebral ventricles, presumably by extension through silicone oil-filled spaces in the optic nerve. (elsevier.com)
- The ____________________ fills the space around the cerebral ventricles of the brain, the central canal of the spinal cord, and the subarachnoid space. (weegy.com)
- The lateral ventricle are one of a system of four communicating cavities within the brain that are continuous with the central canal of the spinal cord. (psyweb.com)
- Thus, SW MR imaging enables noninvasive visualization of the cerebral veins and has shed light on the nature of venous architecture 3 - 5 and cerebral venous malformations. (ajnr.org)
- Brain imaging show cerebral atrophy, enlarged ventricles, and white matter abnormalities. (uniprot.org)
- The authors aimed to develop a fully automated deep learning (DL) model for pediatric cerebral ventricle segmentation and volume calculation for widespread clinical implementation across multiple hospitals. (thejns.org)
- 1,5-7 In fact, no reported case of a pediatric lateral ventricle epidermoid was found in our literature search. (appliedradiology.com)
- There is a 3rd-ventricle epidermoid reported in the pediatric population. (appliedradiology.com)
- We have presented an epidermoid in the lateral ventricle in a pediatric patient. (appliedradiology.com)
- In summary, a lateral ventricle epidermoid is rare and this is the first known reported case in a pediatric patient. (appliedradiology.com)
- Cerebral sulci show mild prominence. (medhelp.org)
- Mild prominence of the cerebral sulci. (medhelp.org)
- Is the mild prominence of the cerebral sulci due to aging only as indicated by the neurologist? (medhelp.org)
- Created from medical scan data, the cerebral geometry accurately defines typical cerebral landmark sulci, gyri and ventricles. (3dscience.com)
- left) with dilatation of all the ventricles. (thefreedictionary.com)
- The trigone of the lateral ventricle is a triangular area defined by the temporal horn inferiorly, the occipital horn posteriorly, and the body of the lateral ventricle anteriorly. (wikipedia.org)
- right and left lateral ventricles are structures within the brain that contain cerebrospinal fluid, a clear, watery fluid that provides cushioning for the brain while also helping to circulate nutrients and remove waste. (healthline.com)
- [bsecho.org] In the present case of impending paradoxical cerebral embolism , the thrombus penetrating the atrial septal wall was visualized by transesophageal echocardiography. (symptoma.com)
- Its roof continues to be bound by the corpus callosum - here known as the tapetum ( carpet ) - and remains separated medially from the other lateral ventricle by the septum pellucidum. (wikipedia.org)
- The aim of this study was to compare flat-panel volumetric CT (VCT) to conventional CT (cCT) in the visualization of the extent of subarachnoid hemorrhage (SAH) and the width of the ventricles in patients with acute SAH. (nih.gov)
- Quantification of Cerebral Ventricle Volume Change of Preterm Neonates" by Yimin Chen, Jessica Kishimoto et al. (uwo.ca)
- In this work, we report on the development and application of a method used to analyze local surface change of the ventricles of preterm neonates with IVH from 3D US images. (uwo.ca)
- The authors present a DL model for automatic ventricle segmentation and volume calculation that is more accurate and rapid than currently available methods. (thejns.org)
- The inferior horn of lateral ventricle or temporal horn , is the largest of the horns. (wikipedia.org)
- As a continuation of the interior side of the ventricular curve, the floor of the body of the ventricle becomes the roof of the inferior horn, hence the tail of the Caudate Nucleus forms the lateral edge of the inferior horn's roof, until, at the extremity of the ventricle, the Caudate Nucleus becomes the Amygdala . (wikipedia.org)