Cephradine: A semi-synthetic cephalosporin antibiotic.Cephalexin: A semisynthetic cephalosporin antibiotic with antimicrobial activity similar to that of CEPHALORIDINE or CEPHALOTHIN, but somewhat less potent. It is effective against both gram-positive and gram-negative organisms.Cephalosporins: A group of broad-spectrum antibiotics first isolated from the Mediterranean fungus ACREMONIUM. They contain the beta-lactam moiety thia-azabicyclo-octenecarboxylic acid also called 7-aminocephalosporanic acid.Cephaloglycin: A cephalorsporin antibiotic.Cefadroxil: Long-acting, broad-spectrum, water-soluble, CEPHALEXIN derivative.Cephaloridine: A cephalosporin antibiotic.Cyclohexanes: Six-carbon alicyclic hydrocarbons.Capsules: Hard or soft soluble containers used for the oral administration of medicine.Ethics, Pharmacy: The principles of proper professional conduct concerning the rights and duties of the pharmacist, relations with patients and fellow practitioners, as well as actions of the pharmacist in health care and interpersonal relations with patient families. (From Stedman, 25th ed)Penicillinase: A beta-lactamase preferentially cleaving penicillins. (Dorland, 28th ed) EC 3.5.2.-.Drugs, Generic: Drugs whose drug name is not protected by a trademark. They may be manufactured by several companies.Patents as Topic: Exclusive legal rights or privileges applied to inventions, plants, etc.Names: Personal names, given or surname, as cultural characteristics, as ethnological or religious patterns, as indications of the geographic distribution of families and inbreeding, etc. Analysis of isonymy, the quality of having the same or similar names, is useful in the study of population genetics. NAMES is used also for the history of names or name changes of corporate bodies, such as medical societies, universities, hospitals, government agencies, etc.Terminology as Topic: The terms, expressions, designations, or symbols used in a particular science, discipline, or specialized subject area.Monomethylhydrazine: Hydrazine substituted by one methyl group.Staphylococcus hominis: A species of STAPHYLOCOCCUS similar to STAPHYLOCOCCUS HAEMOLYTICUS, but containing different esterases. The subspecies Staphylococcus hominis novobiosepticus is highly virulent and novobiocin resistant.Staphylococcus: A genus of gram-positive, facultatively anaerobic, coccoid bacteria. Its organisms occur singly, in pairs, and in tetrads and characteristically divide in more than one plane to form irregular clusters. Natural populations of Staphylococcus are found on the skin and mucous membranes of warm-blooded animals. Some species are opportunistic pathogens of humans and animals.Staphylococcus aureus: Potentially pathogenic bacteria found in nasal membranes, skin, hair follicles, and perineum of warm-blooded animals. They may cause a wide range of infections and intoxications.Coagulase: Enzymes that cause coagulation in plasma by forming a complex with human PROTHROMBIN. Coagulases are produced by certain STAPHYLOCOCCUS and YERSINIA PESTIS. Staphylococci produce two types of coagulase: Staphylocoagulase, a free coagulase that produces true clotting of plasma, and Staphylococcal clumping factor, a bound coagulase in the cell wall that induces clumping of cells in the presence of fibrinogen.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.Developing Countries: Countries in the process of change with economic growth, that is, an increase in production, per capita consumption, and income. The process of economic growth involves better utilization of natural and human resources, which results in a change in the social, political, and economic structures.Software: Sequential operating programs and data which instruct the functioning of a digital computer.Medication Errors: Errors in prescribing, dispensing, or administering medication with the result that the patient fails to receive the correct drug or the indicated proper drug dosage.Waiting Lists: Prospective patient listings for appointments or treatments.Medication Adherence: Voluntary cooperation of the patient in taking drugs or medicine as prescribed. This includes timing, dosage, and frequency.Developed Countries: Countries that have reached a level of economic achievement through an increase of production, per capita income and consumption, and utilization of natural and human resources.Administration, Oral: The giving of drugs, chemicals, or other substances by mouth.Calciphylaxis: Condition of induced systemic hypersensitivity in which tissues respond to appropriate challenging agents with a sudden local calcification.Thiosulfates: Inorganic salts of thiosulfuric acid possessing the general formula R2S2O3.Protective Devices: Devices designed to provide personal protection against injury to individuals exposed to hazards in industry, sports, aviation, or daily activities.Gangrene: Death and putrefaction of tissue usually due to a loss of blood supply.Warfarin: An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.Diagnostic Techniques and Procedures: Methods, procedures, and tests performed to diagnose disease, disordered function, or disability.Necrosis: The pathological process occurring in cells that are dying from irreparable injuries. It is caused by the progressive, uncontrolled action of degradative ENZYMES, leading to MITOCHONDRIAL SWELLING, nuclear flocculation, and cell lysis. It is distinct it from APOPTOSIS, which is a normal, regulated cellular process.Coproporphyria, Hereditary: An autosomal dominant porphyria that is due to a deficiency of COPROPORPHYRINOGEN OXIDASE in the LIVER, the sixth enzyme in the 8-enzyme biosynthetic pathway of HEME. Clinical features include both neurological symptoms and cutaneous lesions. Patients excrete increased levels of porphyrin precursors, 5-AMINOLEVULINATE and COPROPORPHYRINS.Coproporphyrins: Porphyrins with four methyl and four propionic acid side chains attached to the pyrrole rings. Elevated levels of Coproporphyrin III in the urine and feces are major findings in patients with HEREDITARY COPROPORPHYRIA.Coproporphyrinogen Oxidase: An enzyme that catalyzes the oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX by the conversion of two propionate groups to two vinyl groups. It is the sixth enzyme in the 8-enzyme biosynthetic pathway of HEME, and is encoded by CPO gene. Mutations of CPO gene result in HEREDITARY COPROPORPHYRIA.Porphyrias, Hepatic: A group of metabolic diseases due to deficiency of one of a number of LIVER enzymes in the biosynthetic pathway of HEME. They are characterized by the accumulation and increased excretion of PORPHYRINS or its precursors. Clinical features include neurological symptoms (PORPHYRIA, ACUTE INTERMITTENT), cutaneous lesions due to photosensitivity (PORPHYRIA CUTANEA TARDA), or both (HEREDITARY COPROPORPHYRIA). Hepatic porphyrias can be hereditary or acquired as a result of toxicity to the hepatic tissues.Porphyrias: A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.Porphyrins: A group of compounds containing the porphin structure, four pyrrole rings connected by methine bridges in a cyclic configuration to which a variety of side chains are attached. The nature of the side chain is indicated by a prefix, as uroporphyrin, hematoporphyrin, etc. The porphyrins, in combination with iron, form the heme component in biologically significant compounds such as hemoglobin and myoglobin.Porphyrinogens: Colorless reduced precursors of porphyrins in which the pyrrole rings are linked by methylene (-CH2-) bridges.Physician-Patient Relations: The interactions between physician and patient.Injections, Intravenous: Injections made into a vein for therapeutic or experimental purposes.Phytotherapy: Use of plants or herbs to treat diseases or to alleviate pain.Drugs, Chinese Herbal: Chinese herbal or plant extracts which are used as drugs to treat diseases or promote general well-being. The concept does not include synthesized compounds manufactured in China.Universal Precautions: Prudent standard preventive measures to be taken by professional and other health personnel in contact with persons afflicted with a communicable disease, to avoid contracting the disease by contagion or infection. Precautions are especially applicable in the diagnosis and care of AIDS patients.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Cholera Vaccines: Vaccines or candidate vaccines used to prevent infection with VIBRIO CHOLERAE. The original cholera vaccine consisted of killed bacteria, but other kinds of vaccines now exist.Cholera: An acute diarrheal disease endemic in India and Southeast Asia whose causative agent is VIBRIO CHOLERAE. This condition can lead to severe dehydration in a matter of hours unless quickly treated.Vaccines: Suspensions of killed or attenuated microorganisms (bacteria, viruses, fungi, protozoa), antigenic proteins, synthetic constructs, or other bio-molecular derivatives, administered for the prevention, amelioration, or treatment of infectious and other diseases.Vaccines, Inactivated: Vaccines in which the infectious microbial nucleic acid components have been destroyed by chemical or physical treatment (e.g., formalin, beta-propiolactone, gamma radiation) without affecting the antigenicity or immunogenicity of the viral coat or bacterial outer membrane proteins.Cholera Toxin: An ENTEROTOXIN from VIBRIO CHOLERAE. It consists of two major protomers, the heavy (H) or A subunit and the B protomer which consists of 5 light (L) or B subunits. The catalytic A subunit is proteolytically cleaved into fragments A1 and A2. The A1 fragment is a MONO(ADP-RIBOSE) TRANSFERASE. The B protomer binds cholera toxin to intestinal epithelial cells, and facilitates the uptake of the A1 fragment. The A1 catalyzed transfer of ADP-RIBOSE to the alpha subunits of heterotrimeric G PROTEINS activates the production of CYCLIC AMP. Increased levels of cyclic AMP are thought to modulate release of fluid and electrolytes from intestinal crypt cells.

The effect of three frequently applied antibiotics on the colonization resistance of the digestive tract of mice. (1/52)

The influence of treatment with increasing oral doses of three absorbable antibiotics on the colonization resistance of the digestive tract was investigated in mice. Mice treated with ampicillin or epicillin in any of the applied doses had a strongly decreased colonization resistance as demonstrated by 'bacterial overgrowth' after contamination with resistant strains of Escherichia coli. After a treatment period 2 weeks, Streptococcus faecalis became resistant in a number of animals. Oral treatment with cephradine on the other hand had no obvious influence on the endogenous flora of the mice, nor was the colonization resistance decreased.  (+info)

Factors associated with antibiotic resistance in coliform organisms from community urinary tract infection in Wales. (2/52)

Routine susceptibility data for urinary coliform isolates from community practice were analysed in comparison with dispensed antibiotic prescriptions for all conditions and social deprivation data for Bro Taf and North Wales Health Authorities for financial years 1996--1998. Prescribing rates and resistance rates varied widely between practices. Among isolates from practices with high usage of an antibiotic, rates of resistance to that antibiotic tended to be high, and usage correlated significantly with resistance between practice population units. Cross-correlations were found between usage of one antibiotic and resistance to another, particularly for trimethoprim and ampicillin. Usage, particularly of trimethoprim, was associated with multi-resistance to up to four antibiotics. Resistance was more frequent in isolates from males, children and the elderly. Ampicillin resistance correlated with social deprivation. Analyses including or excluding potential repeat isolates yielded closely similar results. Indices reflecting sampling behaviour (laboratory coliform positivity rates, positivity per 1000 registered patients, specimens submitted per 1000 registered patients) varied widely between surgeries, suggesting lack of consensus on urine sampling policies. These indices showed only weak correlations with usage or resistance. Associations between resistance and usage were compared for isolates from two patient subsets that were likely to differ in their proportions of non-Escherichia coli isolates: female patients aged 16--55 years; and males, children and patients aged >55 years. The latter showed higher base levels of resistance, but the associations of resistance with usage were statistically indistinguishable for the two populations. The results suggest that usage of antibiotics in a practice population may affect the rate of urinary infection caused by resistant coliform organisms in that population.  (+info)

Intraperitoneal ciprofloxacin and rifampicin versus cephradine as initial treatment of (C)APD-related peritonitis: a prospective randomized multicenter comparison (CIPPER trial). (3/52)

OBJECTIVE: The initial treatment of peritonitis has evolved from single-agent to combination regimens. The initial response rates improved with these newer regimens but relapsing peritonitis continues to occur. For biofilm-embedded or intracellularly sequestrated bacteria, a combination of intracellularly- and biofilm-active agents such as ciprofloxacin and rifampicin might be beneficial. Many Dutch centers continue to use cephradine as initial treatment, claiming clinically adequate responses with this regimen. We compared the impact of these two regimens on outcome in patients who developed a new episode of peritonitis. DESIGN: Prospective randomized open trial. SETTING: Multicenter study including 14 Dutch dialysis units. PATIENTS AND INTERVENTIONS: From October 1996 to October 1999, 367 patients from 14 centers were randomized to be treated with ciprofloxacin + rifampicin (CR; each 50 mg/L) or cephradine (C; 250 mg/L) in case of peritonitis. Of these 367 patients, 98 developed peritonitis, 44 of whom were treated with CR and 54 with C. MAIN OUTCOME MEASURES: Clinical response, divided into early (during the 2 weeks of therapy) and late (including the following 4 weeks) response. Success was defined as disappearance of all signs and symptoms by days 4-6, through day 42. Bacteriological response was either success (eradication) or failure (persistence, superinfection, or eradication with relapse/reinfection). RESULTS: The groups were comparable for age, sex, duration of continuous ambulatory/automated peritoneal dialysis, and occurrence of diabetes. Bacteriological cultures in both groups revealed predominantly gram-positive micro-organisms. Initial and late clinical successes were obtained in 27/54 and 20/54 episodes (50% and 37%) in the C group, and 33/44 and 28/44 episodes (75% and 63.6%) in the CR group (p = 0.021 and p = 0.019). Bacteriological success occurred in 29.6% in the C group, and in 59.1% in the CR group (p= 0.026), with failure in 46.3% and 18.2%, respectively. Peritonitis episodes were bacteriologically not evaluable in 24.1% of episodes in the C group and 22.7% of episodes in the CR group, due mostly to no growth in the initial culture. CONCLUSION: The CIPPER Trial showed ciprofloxacin + rifampicin to be superior to cephradine as empiric treatment of peritonitis.  (+info)

Prolonged intestinal absorption of cephradine with chitosan-coated ethylcellulose microparticles in rats. (4/52)

Cephradine-containing ethylcellulose microparticles (MPC) were prepared by the solvent evaporation method. Chitosan-coated MPC (Chi-MPC) were prepared by doping MPC with viscous chitosan solution and subsequently drying. When fluorescein isothiocyanate (FITC)-labeled chitosan-coated ethylcellulose microparticles without drug were administered intraduodenally, they moved slowly in the intestine, that is, most of them were retained at the upper and middle parts of the small intestine for more than 8 h, which is considered due to mucoadhesive properties of coated chitosan. When MPC and Chi-MPC was incubated at 37 degrees C in the JP 14 second fluid, pH 6.8, both released the drug slowly with similar release rates. Cephradine solution and suspension, MPC and Chi-MPC were administered intraduodenally to investigate intestinal drug absorption. Only Chi-MPC suppressed the initial plasma level and maintained the plasma concentration for a long time up to 24 h, suggesting Chi-MPC would be useful for prolonged intestinal absorption of cephradine.  (+info)

Is antibiotic penetration compromised in the ischaemic tissues of patients undergoing amputation? (5/52)

Antibiotic prophylaxis is indicated for patients undergoing amputation for severe ischaemia or gangrene. However, the adequacy of tissue levels of antibiotics in ischaemic tissue is not known. In this study the serum and tissue antibiotic levels were measured after intravenous administration of metronidazole (15 mg/kg body weight) and cephradine (20 mg/kg body weight). In 11 patients, venous samples were taken at time 0 (induction of anaesthesia) 10, 30 and 60 min. Samples of 2 g each of fat and muscle were collected from the amputation site and three distal sites. Metronidazole and cephradine levels were measured and the degree of limb ischaemia estimated preoperatively by an isotope limb blood flow method. Our results indicate that both metronidazole and cephradine penetrate ischaemic tissues to levels equivalent of a Mean Inhibitory Concentration (MIC) 50 for most organisms encountered in vascular surgery, and that the degree of ischaemia does not alter this.  (+info)

Occupational contact allergy to cephalosporins. (6/52)

Contact sensitivity to systemically administered drugs occurs mainly among healthcare workers and is frequently caused by antibiotics. A 32-year-old nurse presented with a 1(1/2) year history of hand dermatitis and a 2 month history of palpebral eczema, which were clearly work related. Patch tests with standard and gloves series were negative. Testing of the products commonly handled by the patient were positive for cefradine and cefazolin. Testing of other cephalosporins the patient had not come in contact with were also positive for cefuroxime, ceftriaxone, and cefotaxime. This cross-reactivity may be explained by similar molecular structures. The patient stopped preparing cephalosporin solutions for systemic administration and the lesions cleared.  (+info)

Comparative study of cephradine and amoxicillin-clavulanate in the treatment of recurrent urinary tract infections. (7/52)

Eighty-eight female patients with a history of recurrent urinary tract infections were treated according to a randomization scheme with either 1 g of cephradine every 12 h (47 patients) or 375 mg of amoxicillin-clavulanate every 8 h (41 patients) for 7 days. The treatments were equally effective (cure rates of 89% for cephradine and 88% for amoxicillin-clavulanate) and showed similar relapse rates (cephradine, 14%; amoxicillin-clavulanate, 11%). Adverse effects were similar in both groups (cephradine, 23%; amoxicillin-clavulanate, 22%).  (+info)

Comparison of in vitro activity of cephalexin, cephradine, and cefaclor. (8/52)

Inhibitory activity of cephalexin, cephradine, and cefaclor was compared by the WHO-ICS agar dilution technique. Cefaclor was substantially more active against staphylococci, streptococci, gonococci, meningococci, Haemophilus, Escherichia coli, Klebsiella pneumoniae, Citrobacter diversus, Proteus mirabilis, salmonellae, and shigellae than was cephalexin, which in turn was more active than cephradine. Cefaclor appeared to be less resistant to staphylococcal penicillinase than did the other two agents. None of these cephalosporins was active against Enterobacter, Serratia, indole-positive Proteeae, Pseudomonas, or Bacteroides fragilis.  (+info)

Methicillin-resistant staphylococci were tested for susceptibility to cephradine, cephaloridine, cephalexin, and cefuroxime and 30 degree C and 37 degree C on ordinary media and on media of enhanced osmotic strength. The coagulase-negative strains were divided into Staphylococcus epidermis and Staphylococcus hominis. Generally the number of susceptible strains decreased with low incubation temperature and osmotic support. When Staphylococcus aureus was tested against cephalexin and cefuroxime, most were susceptible at 37 degree C whereas all were resistant at 30 degree C. A similar trend was found in the case of cephradine, where it was accentuated by osmotic support. While almost all strains of Staph. epidermidis were sensitive to all four drugs under all test conditions, the susceptibility of Staph. hominis was generally decreased by either lower incubation temperature or osmotic support or both.. ...
Cephradine (Eskacef - SKF; Velosef - Squibb) is a new semi-synthetic cephalosporin for oral use. Like other cephalosporins it is active against both Gram-negative and Gram-positive pathogens, apparently including penicillinase-producing staphylococci (though this has been questioned1). It is advertised as having new striking power, but from the data provided its spectrum of activity closely resembles that of cephalexin (Ceporex - Glaxo; Keflex - Lilly),2 and the promotional literature on cephradine makes no direct comparison between the two drugs.. ...
VOLVOCEF (Cephradine) is a first-generation cephalosporin antibacterial given orally and by parenteral route in the treatment of susceptible infections and
The IUPHAR/BPS Guide to Pharmacology. cephradine ligand page. Quantitative data and detailed annnotation of the targets of licensed and experimental drugs.
A significant number of paediatric surgical patients undergone clean surgical procedures. Most of the paediatric surgeon use perioperative prophylactic antibiotic in this clean procedure because of undue fear of infection in their mind. The objective of this study is to evaluate whether the use of perioperative prophylactic antibiotics have an effect to prevent post operative wound infection in clean operation in paediatric surgical patients. This study was conducted in the paediatric surgery department of Bangabandhu Sheikh Mujib Medical University and some private clinics of Dhaka city from January 2009 to December 2009. Two hundred patients who were undergone clean elective surgical procedure on day case basis were included in this study. They were divided into two equal groups (Group A and Group B). The patients of Group A were given intransverse Cephradine 30 minutes before incision and then oral Cephradine was advised postoperatively for 7 days. The patients of Group B were not given any
The information contained herein has been obtained from sources that the Company believes to be reliable, however, the Company has not independently verified or confirmed the information and the recipient acknowledges that no representations or warranties are being made in connection with the use of the information.. ...
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice. ...
Susceptibility of Anaerobic Bacteria to Cefoxitin and Related Compounds: Cephalothin, cefazolin, cephradine, and cefoxitin inhibited more than 75% of 326 anaero
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TY - JOUR. T1 - Characterization of the Oral Absorption of β-Lactam Antibiotics. I. Cephalosporins. T2 - Determination of Intrinsic Membrane Absorption Parameters in the Rat Intestine In Situ. AU - Sinko, Patrick J.. PY - 1988/10. Y1 - 1988/10. N2 - The oral absorption of five cephalosporin antibiotics, cefaclor, cefadroxil, cefatrizine, cephalexin, and cephradine, has been studied using a single-pass intestinal perfusion technique in rats. Intrinsic membrane absorption parameters, "unbiased" by the presence of an aqueous permeability (diffusion or stagnant layer), have been calculated utilizing a boundary layer mathematical model. The resultant intrinsic membrane absorption parameters are consistent with a significant carrier-mediated, Michaelis-Menten-type kinetic mechanism and a small passive component in the jejunum. Cefaclor colon permeability is low and does not exhibit concentration dependent behavior. The measured carrier parameters (±SD) for the jejunal perfusions are as follows: ...
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Forty-seven Salmonella Typhimurium (33 zoonotic, 14 clinical) strains were tested for antimicrobial resistance using the standard disk diffusion method. The presence of relevant resistance genes and class 1 integrons were investigated by using PCR. Pulsed-field gel electrophoresis (PFGE) and plasmid profiling were carried out to determine the genomic diversity of Salmonella Typhimurium. Approximately 57.4 of the S. Typhimurium strains were multidrug resistant (MDR) and showed high resistance rates to tetracycline (70.2), sulfonamides (57.4), streptomycin (53.1), ampicillin (29.7), nalidixic acid (27.6), kanamycin (23.4), chloramphenicol (21.2), and trimethoprim (19.1). Resistance towards cephalosporins was noted for cephalothin (27.6), cephradine (21.2), amoxicillin clavulanic acid (17.0), and cephalexin (17.0). Resistance genes, bla(TEM), strA, aadA, sul1, sul2, tetA, tetB, and tetC, were detected among the drug-resistant strains. Thirty-three strains (70.2) carried class 1 integrons, which ...
Bestatin [(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl-L-leucine], a dipeptide containing an unusual amino acid, has been used clinically as an anticancer agent in p.o. dosage form. We examined the transport characteristics of [3H]bestatin by rabbit intestinal brush-border membrane vesicles. Bestatin uptake was stimulated by an inward H+ gradient (overshoot phenomenon) and by an interior-negative membrane potential. About half of the apparent bestatin uptake at 1 mM by brush-border membrane vesicles was estimated as binding to the membranes. The affinity constant for the bestatin transport was 0.52 mM. The uptake of bestatin by brush-border membrane vesicles was inhibited by p.o. cephalosporins and dipeptides, but not by amino acids. In vesicles preloaded with either bestatin, cephradine or glycylsarcosine, the uptake of [3H]bestatin was stimulated markedly (countertransport effect). These results indicate that bestatin is transported via the H+/dipeptide transport system in rabbit intestinal ...
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Learn about the prescription drug Cephalexin (Keflex), including information about its uses, dosage, side effects, and common interactions.
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Pregnancy and breast-feeding: if you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Cefadroxil while you are pregnant. Cefadroxil is found in breast milk. If you are or will be breast-feeding while you use Cefadroxil , check with your doctor. Discuss any possible risks to your baby ...
Keflex is the brand name of the drug cephalexin. Cephalexin is an antibiotic in a class called cephalosporins. These work by preventing bacteria from...
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At this point, I went to a much stronger, antibiotic: Cephalexin. I gave her 500 mg of this for three weeks. At this point the cut was covering about 25% of her paw and I was thinking that the cephalaxin would definitely clear this up. Cephalaxin is one of the strongest antibiotics out there and it has worked MIRACLES for me in the past. So I was feeling very confident that this cut would be gone in about three weeks ...
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Staphylococcus aureus subsp. aureus ATCC ® 6538PNA™ Designation: FDA 209P TypeStrain=False Application: Assay of Assay of amikacin Assay of cefactor Assay of cefadroxil Assay of cefamandole Assay of cefazolin Assay of cefotaxime Assay of cefoxitin Assay of cephalexin Assay of cephaloglycin Assay of cephaloridine cephalomycin Enteric Research Assay of cephalothin Assay of cephapirin Assay of cephradine Assay of chlortetracycline aureomycin Assay of cloxacillin Assay of cycloserine D-4-amino-3-isoxazolidone Assay of demeclocycline demethylchlortetracycline Assay of dicloxacillin Assay of doxycycline hydramycin Assay of erythromycin Assay of framycetin Assay of gentamicins gentamicin Assay of gramicidin Assay of kanamycin Assay of lincomycin Assay of meclocycline Assay of methacycline Assay of methicillin Assay of nafcillin Assay of neomycin Assay of oxacillin Assay of oxytetracycline terramycin Assay of penicillin Assay of plicamycin mithramycin Assay of rolitetracycline Assay of spiramycin
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S3). Reductions in mean CFU counts between S1 and S2 (p < 0.0001) as well as between S2 and S3 (p < 0.0001) were statistically significant, indicating the effectiveness of a triple antibiotic paste in the disinfection of immature teeth with apical periodontitis. Recently, a modified triple antibiotic paste dressing (ciprofloxacin, metronidazole and cefixime, a third generation broad spectrum cephalosporin) (mTAP) at concentration of 20 mg of each antibiotic, has been shown to improve the success rate of the revascularization procedure in immature dog teeth with AP x. However, the results of some studies concluded that the use of intracanal antibiotics might not be necessary in REPs in immature dogs teeth with apical periodontitis. A study carried out by Da Silva et al. xi found that teeth treated with sodium hypochlorite irrigation with the EndoVac system alone, presented more exuberant mineralized formations, more structured apical and periapical connective tissue, and a more advanced repair ...
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Cephalexin is a Generic name for a first-generation cephalosporin antibiotic that works by fighting bacteria in the body. It is usually prescribed to treat respiratory tract, skin, bone, middle ear and UTI - urinary tract infections. Cephalexin and other cephalosporins are broad-spectrum antibiotics are used to treat a various types of infections caused by many different bacteria. It is effective against both gram-negative and gram-positive bacteria. This drug is also used to prevent infections that are caused by streptococcal bacteria, including rheumatic fever. However, cephalexin isnt appropriate for sinus infections. Cephalexin should only be used when theres strong evidence to support its use. Misusing of cephalosporins can lead to serious infections from drug-resistant bacteria. Treating colds or flu symptoms with broad-spectrum antibiotics such as cephalexin can lead to antibiotic resistance and more severe infections that will be far harder to treat. Cephalexin is available in the ...
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Pseudomembranous colitis is an inflammatory disease of the colon (see image below). It has changed in the last 100 years from a fatal disease caused by a postoperative event to, in the era of antibiotics, a commonly occurring complication of antibiotic use that may lead to serious morbidity but that usually is treated easily.
SKC sold only two cephalosporins-Ancef and Anspor (cephradine). Lilly dominated the cephalosporin market with its sales of ...
... (INN) (formerly cephradine BAN) is a first generation cephalosporin antibiotic. Cefradine has similar spectrum of ... Cephradine (Kojar and Root), Ceponin (Chi Sheng), Lacef (Tai Yu), Licef-A and Lisacef (Taiwan Biotech), Lofadine (Gentle), ... Cephradine (New Asiatic Pharm and Sine Pharm), Kebili (Baiyunshan), Saifuding (The United Laboratories Ltd), Shen You (Shyndec ... Cephradine (Eipico), Cephraforte (Sina), Farcosef (PBI)Fortecef (Meivo), Mepadrin (Mepaco), Ultracef (Misr) and Velosef ( ...
McAfee and Smith recommend a course of oral antibiotics, usually oxacillin sodium or cephradine, and assert that surgery and ...
As an example three drugs from this class (Cephalexin, Cephradine and Cefadroxil) all have a single methyl group at position C- ...
... cephradine MeSH D02.065.589.099.249.210 --- cephaloridine MeSH D02.065.589.099.249.210.150 --- ceftazidime MeSH D02.065.589.099 ...
... is typically used to treat hypothyroidism,[9] and is the treatment of choice for people with hypothyroidism,[10] who often require lifelong thyroid hormone therapy.[11] It may also be used to treat goiter via its ability to lower thyroid-stimulating hormone (TSH), a hormone that is considered goiter-inducing.[12][13] Levothyroxine is also used as interventional therapy in people with nodular thyroid disease or thyroid cancer to suppress thyroid-stimulating hormone (TSH) secretion.[14] A subset of people with hypothyroidism treated with an appropriate dose of levothyroxine will describe continuing symptoms despite TSH levels in the normal range.[11] In these people, further laboratory and clinical evaluation is warranted as they may have another cause for their symptoms.[11] Furthermore, it is important to review their medications and possible dietary supplements as several medications can affect thyroid hormone levels.[11] Levothyroxine is also used to treat subclinical ...
... is a low cost drug.[7] In the United States, Salix Pharmaceuticals holds a US Patent for rifaximin and markets the drug under the name Xifaxan.[17][18] In addition to receiving FDA approval for traveler's diarrhea and (marketing approved for)[18] hepatic encephalopathy, rifaximin received FDA approval for IBS in May 2015.[19] No generic formulation is available in the US and none has appeared due to the fact that the FDA approval process was ongoing. If rifaximin receives full FDA approval for hepatic encephalopathy it is likely that Salix will maintain marketing exclusivity and be protected from generic formulations until March 24, 2017.[18] Rifaximin is approved in 33 countries for GI disorders.[20][21] On August 13, 2013, Health Canada issued a Notice of Compliance to Salix Pharmaceuticals Inc. for the drug product Zaxine.[22] In India it is available under the brand names Ciboz and Xifapill.[citation needed] In Russia and Ukraine the drug is sold under the name Alfa Normix ...
Long-term use of methylprednisolone, as with all corticosteroids, can be associated with hyperglycemia, decreased resistance to infection, swelling of face, weight gain, congestive cardiac insufficiency, fluid and sodium retention, edema, hypertension, increased eye pressure, glaucoma, osteoporosis, and psychosis, especially when used at high doses.[11][12] The most serious side effect occurs after the adrenal glands cease natural production of cortisol, which methylprednisolone will replace. Abrupt cessation of the drug after this occurs can result in a condition known as Addisonian crisis, which can be fatal. To prevent this, the drug is usually prescribed with a tapering dose, including a predosed "dose pack" detailing a specific number of tablets to take at designated times over a several-day period. Pharmacists sometimes advise that this drug may cause sleeplessness and "down" moods. Measles and chicken pox are very dangerous and potentially fatal for people on methylprednisolone therapy. ...
Important drug interactions are rare.[27][28] However, the most significant major drug interaction concern is the decreased activation of clopidogrel when taken together with omeprazole.[29] Although still controversial,[30] this may increase the risk of stroke or heart attack in people taking clopidogrel to prevent these events. This interaction is possible because omeprazole is an inhibitor of the enzymes CYP2C19 and CYP3A4.[31] Clopidogrel is an inactive prodrug that partially depends on CYP2C19 for conversion to its active form. Inhibition of CYP2C19 may block the activation of clopidogrel, which could reduce its effects.[32][33] Almost all benzodiazepines are metabolised by the CYP3A4 and CYP2D6 pathways, and inhibition of these enzymes results in a higher AUC (i.e., the total effect over time of a given dose). Other examples of drugs dependent on CYP3A4 for their metabolism are escitalopram,[34] warfarin,[35] oxycodone, tramadol, and oxymorphone. The concentrations of these drugs may ...
Bonow RO, Carabello BA, Kanu C, et al. (August 2006). "ACC/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (writing committee to revise the 1998 Guidelines for the Management of Patients With Valvular Heart Disease): developed in collaboration with the Society of Cardiovascular Anesthesiologists: endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons". Circulation. 114 (5): e84-231. doi:10.1161/CIRCULATIONAHA.106.176857. PMID 16880336 ...
... has been investigated for use as a radiation countermeasure. Its value as a radiation countermeasure is based mainly on its stimulation of production of white blood cells and platelets.[6] Its potential use as a radiation countermeasure was developed by the Armed Forces Radiobiology Research Institute (AFRRI) and subsequently studied by AFRRI and Hollis-Eden Pharmaceuticals under the proposed brand name Neumune for the treatment of acute radiation syndrome.[6][7] The clinical trials with rhesus monkeys were successful. According to the Hollis-Eden report, only 12.5% of the 40 Neumune-treated animals died versus 32.5% in the placebo group.[8] Hollis-Eden had applied for a contract from the U.S. Government under the BioShield Request for Proposals (RFP) for radiation countermeasures. After being encouraged for 2.5 years that Neumune was in the competitive range, on March 9, 2007, the RFP was canceled by HHS. According to HHS, "the product was no longer in the competitive ...
... (CBZ), sold under the trade name Tegretol among others, is an anticonvulsant medication used primarily in the treatment of epilepsy and neuropathic pain.[1] It is not effective for absence or myoclonic seizures.[1] It is used in schizophrenia along with other medications and as a second-line agent in bipolar disorder.[3][1] Carbamazepine appears to work as well as phenytoin and valproate for focal and generalised seizures.[4] Common side effects include nausea and drowsiness.[1] Serious side effects may include skin rashes, decreased bone marrow function, suicidal thoughts, or confusion.[1] It should not be used in those with a history of bone marrow problems.[1] Use during pregnancy may cause harm to the baby; however, stopping the medication in pregnant women with seizures is not recommended.[1] Its use during breastfeeding is not recommended.[1] Care should be taken in those with either kidney or liver problems.[1] Carbamazepine was discovered in 1953 by Swiss chemist Walter ...
... is an allosteric endocannabinoid, as it is a negative allosteric modulator of the CB1 receptor.[4][5] Pregnenolone is involved in a natural negative feedback loop against CB1 receptor activation in animals.[6][better source needed] It prevents CB1 receptor agonists like tetrahydrocannabinol, the main active constituent in cannabis, from fully activating the CB1 [6][better source needed] Pregnenolone has been found to bind with high, nanomolar affinity to microtubule-associated protein 2 (MAP2) in the brain.[7][8] In contrast to pregnenolone, pregnenolone sulfate did not bind to microtubules.[7][8] However, progesterone did and with similar affinity to pregnenolone, although unlike pregnenolone, it did not increase binding of MAP2 to tubulin.[7][8] Pregnenolone was found to induce tubule polymerization in neuronal cultures and to increase neurite growth in PC12 cells treated with nerve growth factor.[7][8] As such, pregnenolone may control formation and stabilization of microtubules ...
... has little systemic absorption, and is considered safe for topical use in adults and children over the age of 2 months. The FDA has assigned it as pregnancy category B. Animal studies have shown no effects on fertility or teratogenicity, but studies in humans have not been performed. The excretion of permethrin in breastmilk is unknown, and breastfeeding is recommended to be temporarily discontinued during treatment.[11] According to the Connecticut Department of Public Health, permethrin "has low mammalian toxicity, is poorly absorbed through the skin, and is rapidly inactivated by the body. Skin reactions have been uncommon."[14] Excessive exposure to permethrin can cause nausea, headache, muscle weakness, excessive salivation, shortness of breath, and seizures. Worker exposure to the chemical can be monitored by measurement of the urinary metabolites, while severe overdose may be confirmed by measurement of permethrin in serum or blood plasma.[15] Permethrin does not present any ...
InChI=1S/C22H22N2O8/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29/h4-6,10,14-15,17,25,27-29,32H,1H2,2-3H3,(H2,23,31)/t10-,14-,15+,17+,22+/m1/s1 ...
Human exposure to methoxychlor occurs via air, soil, and water,[7] primarily in people who work with the substance or who are exposed to air, soil, or water that has been contaminated. It is unknown how quickly and efficiently the substance is absorbed by humans who have been exposed to contaminated air or via skin contact.[7] In animal models, high doses can lead to neurotoxicity.[7] Some methoxychlor's metabolites have estrogenic effects in adult and developing animals before and after birth.[7] One studied metabolite is 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane (HPTE) which shows reproductive toxicity in an animal model by reducing testosterone biosynthesis.[8][9] Such effects adversely affect both the male and female reproductive systems. It is expected that this "could occur in humans" but has not been proven.[7] While one study has linked methoxychlor to the development of leukemia in humans, most studies in animals and humans have been negative, thus the EPA has determined that it is ...
... , also known as eltanolone (INN), is an endogenous neurosteroid that is biosynthesized from progesterone.[1] It is a positive allosteric modulator of the GABAA receptor,[1] as well as a negative allosteric modulator of the glycine receptor,[2] and is known to have sedative, anxiolytic, anesthetic, and anticonvulsant effects.[1][2][3] It was investigated for clinical use as a general anesthetic, but produced unwanted side effects such as convulsions on occasion, and for this reason was never marketed.[2][4] During pregnancy, pregnanolone and allopregnanolone are involved in sedation and anesthesia of the fetus.[5][6] ...
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A component in various medicinal plants (e.g. Scutellaria baicalensis), chrysin is a dihydroxyflavone, a type of flavonoid.[6] It is also found in honey, propolis, the passion flowers, Passiflora caerulea and Passiflora incarnata, in Oroxylum indicum,[2] carrots,[1] chamomile,[7] many fruits, and in mushrooms, such as the mushroom, Pleurotus ostreatus.[6] It is extracted from various plants,[1] such as the blue passion flower (Passiflora caerulea).[1] The amount of chrysin in honey from various plant sources is about 0.2 mg per 100 g.[8] Chrysin is typically found at higher amounts in propolis than in honey.[9] A 2010 study found the amount of chrysin was 0.10 mg/kg in honeydew honey, and 5.3 mg/kg in forest honeys.[10] A 2010 study found the amount of chrysin in propolis was as much as 28 g/L.[10] A 2013 study found the amount of chrysin in various mushrooms from the island of Lesvos, Greece varied between 0.17 mg/kg in Lactarius deliciosus to 0.34 mg/kg in Suillus bellinii.[10] ...
Recreational use of tianeptine is rare[according to whom?] and thus far has only been seen in persons already using multiple substances for recreational purposes.[citation needed] In 2001, Singapore's Ministry of Health restricted tianeptine prescribing to psychiatrists due to its recreational potential,[49] In 2003, Bahrain classified it a controlled substance due to increasing reports of misuse and recreational use.[50] Between 1989 and 2004, in France 141 cases of recreational use were identified, correlating to an incidence of 1 to 3 cases per 1000 persons treated with tianeptine and 45 between 2006 and 2011. The main reason for recreational use is to achieve an anxiolytic effect. According to Servier, stopping of treatment with tianeptine is difficult, due to the possibility of withdrawal symptoms in a person. The severity of the withdrawal is dependent on the daily dose, with high doses being extremely difficult to quit.[51][better source needed][52][53] In 2007, according to French Health ...
... is very toxic to cats which cannot tolerate the therapeutic doses for dogs.[7] This is associated with UGT1A6 deficiency in cats, the enzyme responsible for metabolizing cypermethrin. As a consequence, cypermethrin remains much longer in the cat's organs than in dogs or other mammals and can be fatal in large doses. In male rats cypermethrin was shown to exhibit a toxic effect on the reproductive system. After 15 days of continual dosing, both androgen receptor levels and serum testosterone levels were significantly reduced. These data suggested that cypermethrin can induce impairments of the structure of seminiferous tubules and spermatogenesis in male rats at high doses.[8] Long-term exposure to cypermethrin during adulthood is found to induce dopaminergic neurodegeneration in rats, and postnatal exposure enhances the susceptibility of animals to dopaminergic neurodegeneration if rechallenged during adulthood.[9] If exposed to cypermethrin during pregnancy, rats give birth to ...
Biosynthesis of mevastatin is primarily accomplished via a type 1 PKS pathway it proceeds in the PKS pathway as seen in figure 1 until it reaches a hexaketide state where it undergoes a Diels-Alder cyclization. After cyclization it continues via the PKS pathway to a nonaketide after which it is released and undergoes oxidation and dehydration. It is presumed that the oxidations are preformed by a polypeptide that is similar to cytochrome p450 monooxygenase, which is encoded by mlcC within the mevastatin gene. Lastly the biosynthesis is completed by the PKS facilitating the addition of a diketide sidechain and a methylation by SAM.[7] Figure 1 shows mevastatin in its acid form but it can also be in the more commonly seen lactone form. This pathway was first observed in Penicillium cilrinum and was later discovered that another type of fungus, Penicillium brevicompaetum also produced mevastatin via a PKS pathway. ...
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It is commonly available without a prescription in various dosage forms, such as a topical cream, ointment, or vaginal suppository. It is also available as an oral troche or throat lozenge as a prescription only. Topically, clotrimazole is used for vulvovaginal candidiasis (yeast infection) or yeast infections of the skin. For vulvovaginal candidiasis (yeast infection), clotrimazole tablets and creams are inserted into the vagina. Topical clotrimazole is usually not effective in treatment of fungal infections of the scalp or nails.[citation needed] When using over-the-counter drug clotrimazole products, use should be discontinued if condition does not improve after treatment for 2 weeks for jock itch or after 4 weeks for athlete's foot or ringworm.[6] Throat lozenge preparations are used for oropharyngeal candidiasis (oral thrush) or prevention of oral thrush in people with neutropenia.[6] Clotrimazole is usually used 5 times daily for 14 days for oral thrush, twice daily for 2 to 8 weeks for ...
... (5α-DHP), also known as allopregnanedione,[1] as well as 5α-pregnane-3,20-dione, is an endogenous progestogen and neurosteroid that is synthesized from progesterone.[2][3] It is also an intermediate in the synthesis of allopregnanolone and isopregnanolone from progesterone. 5α-DHP is an agonist of the progesterone receptor and a positive allosteric modulator of the GABAA receptor (albeit with an affinity for this receptor that is regarded as relatively low (in comparison to 3α-hydroxylated progesterone metabolites such as allopregnanolone and pregnanolone)).[2][3][4][5] It has also been found to act as a negative allosteric modulator of the GABAA-rho receptor.[6] In addition, it is a weak agonist of the pregnane X receptor (PXR) (EC50 ,10,000 µM)), with approximately six-fold lower potency relative to its 5β-isomer, 5β-dihydroprogesterone.[7]. ...
Cephradine (Eskacef - SKF; Velosef - Squibb) is a new semi-synthetic cephalosporin for oral use. Like other cephalosporins it ... 2 and the promotional literature on cephradine makes no direct comparison between the two drugs. ...
cephradine ligand page. Quantitative data and detailed annnotation of the targets of licensed and experimental drugs. ...
Effects of test conditions on the susceptibility of staphylococci in vitro to cephradine, cephaloridine, cephalexin, and ... Effects of test conditions on the susceptibility of staphylococci in vitro to cephradine, cephaloridine, cephalexin, and ... Methicillin-resistant staphylococci were tested for susceptibility to cephradine, cephaloridine, cephalexin, and cefuroxime and ... A similar trend was found in the case of cephradine, where it was accentuated by osmotic support. While almost all strains of ...
Cephradine) is a first-generation cephalosporin antibacterial given orally and by parenteral route in the treatment of ... VOLVOCEF (Cephradine) Capsules 250mg are available in pack of 10s.. VOLVOCEF (Cephradine) Capsules 500mg are available in pack ... Cephradine is contraindicated in patients with known hypersensitivity to cephradine or to any excipient of the product. ... VOLVOCEF 125mg 5mLDry Suspension (Cephradine). VOLVOCEF (Cephradine) is a first-generation cephalosporin antibacterial given ...
Cephradine] [Chlorambucil] *Chloramphenicol *Chlordiazepoxide *Chlormezanone Chloroform *Chlorpropamide Cinnarizine Clemastine ...
is recalling Cephradine Capsules because of Subpotency (stability).. PRODUCT. Cephradine Capsules USP, 250 mg in bottles of 100 ... Teva Pharmaceuticals Recalls Cephradine Capsules. Sellersville, PA (SafetyAlerts) - The Food and Drug Administration (FDA) ...
The generic ingredient in VELOSEF is cephradine. There are ten drug master file entries for this compound. Additional details ...
Find information on Cephradine (Velosef) in Daviss Drug Guide including dosage, side effects, interactions, nursing ... cephradine is a topic covered in the Daviss Drug Guide. To view the entire topic, please sign in or purchase a subscription. ... "Cephradine." Daviss Drug Guide, 16th ed., F.A. Davis Company, 2020. Emergency Central, emergency.unboundmedicine.com/emergency ... Davis-Drug-Guide/109032/all/cephradine. Quiring C, Sanoski CA, Vallerand AH. Cephradine. Daviss Drug Guide. F.A. Davis Company ...
Cephradine Market Research Report 2019-2025 having 118.00 pages and available at USD 3,280.00 from MarketResearchReports.com ... Figure Cephradine Value Chain. Table Cephradine Distributors List. Table Cephradine Customers List. Table Porters Five Forces ... Figure Cephradine Product Picture. Table Cephradine Key Market Segments. Table Major Manufacturers Cephradine Covered in This ... 2.1.1 Global Cephradine Production Value 2014-2025. 2.1.2 Global Cephradine Production 2014-2025. 2.1.3 Global Cephradine ...
Cephradine capsules. What are cephradine capsules?. CEPHRADINE (Anspor®, Velosef®) is a cephalosporin antibiotic. It treats ... Cephradine oral suspension. What is cephradine oral suspension?. CEPHRADINE (Anspor®, Velosef®) is a cephalosporin antibiotic. ... Generic cephradine capsules are available.. What should my health care professional know before I take cephradine?. They need ... Generic cephradine oral suspension is available.. What should my health care professional know before I take cephradine?. They ...
VELOSEF (Cephradine). *Cephradine is an effective antibiotic and is responsive to both gram-positive and gram-negative bacteria ... Even though no reaction was seen in rodent mammals in their pregnancy stage; when cephradine was given to them. Still caution ... After cephradine dosage, heartburn and chest pain can be evident. But its normal. ... Several strains of Enterobacteria are pathogenic and Cephradine is not efficient against them. ...
Cephradine. Cefradine is reported as an ingredient of Supracef in the following countries:. *Bangladesh ...
Since cephradine is excreted in breast milk during lactation, caution should be exercised when cephradine is administered to a ... Velosef Capsules (Cephradine Capsules USP). Velosef 250 250 mg/capsule:. bottles of 24 (NDC 0003-0113-24). and 100 (NDC 0003- ... oral dosage forms include capsules containing 250 mg and 500 mg cephradine and cephradine for oral suspension containing, after ... Cephradine is active against the following organisms in vitro:. Group A beta-hemolytic streptococci. Staphylococci, including ...
Cephradine/Velacef. - Adult: 0.5 gm PO q6hr. - Good diffusion from blood into CSF only with inflammation;. - 80-95 % of dose ...
CEPHRADINE , SQ 11436 , SK&F D-39304 , CEFRADINE , SQ 22022 [DIHYDRATE] , ANSPOR , SQ-22022 , NICEF , VELOSEF 125 , VELOSEF ... CEPHRADINE. ChEMBL Synonyms Ecosporina , VELOSEF 250 , VELOSEF , CEPHRADINE , SQ 11436 , SK&F D-39304 , CEFRADINE , SQ 22022 ... Cefradine , VELOSEF , ANSPOR , NICEF , VELOSEF 125 , VELOSEF 500 , CEPHRADINE , Ecosporina , VELOSEF 250. ... CEPHRADINE , Ecosporina , VELOSEF 250, Synonyms:Ecosporina , VELOSEF 250 , VELOSEF , ...
Research and Markets (http://www.researchandmarkets.com/research/nm6nz9/cephalosporin) has announced the addition of the
Specifications cephradine 1.Our products are sold to Europe and America 2.purity: 99% 3.packing: 25kg/drum 4.delivery: 3-5 days ...
cephradine capsule. On Label. RX. 0 Reviews. cefoxitin Solution, Reconstituted (Recon Soln). On Label. RX. 0 Reviews. ...
Looking for medication to treat bacterial+urinary+tract+infection? Find a list of current medications, their possible side effects, dosage, and efficacy when used to treat or reduce the symptoms of bacterial+urinary+tract+infection
Cephalexin, cephradine, amoxicillin. 2 gm PO 1 hour prior to procedure. Discontinued within 24 hours of the procedure. For most ...
For cephradine. *For bacterial infections: *For oral dosage forms (capsules or oral suspension): *Adults and teenagers-250 ... Cephradine. Description. Cephalosporins (sef-a-loe-SPOR-ins) are used in the treatment of infections caused by bacteria. They ...
Make sure any doctor or dentist who treats you knows that you are using this medicine. You may need to stop using this medicine several days before having surgery or medical tests. Check with your doctor immediately if you have diarrhea, fever, or any symptoms of an infection. This medicine may cause skin necrosis or gangrene. Call your doctor right away if you have pain, a color change, or a temperature change to any area of your body. Call your doctor right away if you have pain in your toes and they look purple or dark in color. These could be signs of a serious medical problem. Calciphylaxis or calcium uremic arteriolopathy may occur in patients with or without end-stage kidney disease. Tell your doctor right away if you have purplish red, net-like, blotchy spots on the skin. This medicine may increase your chance of bleeding. Check with your doctor right away if you notice any unusual bleeding or bruising, black, tarry stools, blood in the urine or stools, or pinpoint red spots on your ...
Acute intermittent porphyria (AIP) is one of the porphyrias, a group of diseases involving defects in heme metabolism and that results in excessive secretion of porphyrins and porphyrin precursors. AIP manifests itself by abdomen pain, neuropathies, and constipation, but, unlike most types of porphyria, patients with AIP do not have a rash.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.. ...
  • Keflex - Lilly), 2 and the promotional literature on cephradine makes no direct comparison between the two drugs. (bmj.com)
  • When expressed in Xenopus oocytes, rat PepT1 stimulated the uptake of ceftibuten (anion) and cephradine (zwitterion) in the presence of an inward H+ gradient, and the expressed uptake was inhibited by excess dipeptides. (aspetjournals.org)
  • Kinetic analysis revealed that ceftibuten has 14-fold higher affinity for the rat PepT1 than cephradine. (aspetjournals.org)
  • Cephradine is an effective antibiotic and is responsive to both gram-positive and gram-negative bacteria. (blogspot.com)
  • In vitro studies by an ultracentrifugation technique show that at therapeutic serum antibiotic concentrations, cephradine is minimally bound (8 to 17 percent) to normal serum protein. (drugs.com)
  • Cephradine is a broad spectrum, bactericidal antibiotic active against both Gram positive and Gram negative bacteria. (intekom.com)
  • Chemically, cephradine is (6R,7R)-7-[(R)-2-Amino-2-(1,4-cyclohexadien-1-yl)acetamido] -3- methyl-8-oxo-5-thia-1-azabicyclo[4.2.ct-2-ene-2-carboxylic acid. (amrospharma.com)
  • CEFRIL products contain Cephradine which is a semi-synthetic cephalosporin chemically designated as 7-[D-2-amino-2-(1,4-cychlohexadien-1-yl) acetamido]-3-methyl-8-oxo- 5- thia-1- azabicyclo [4.2.ct-2-ene-2-carboxylic acid. (intekom.com)
  • VOLVOCEF (Cephradine) is a first-generation cephalosporin antibacterial given orally and by parenteral route in the treatment of susceptible infections and in the prophylaxis of infections during surgical procedures. (amrospharma.com)
  • When tested by in vitro methods, staphylococci exhibit cross-resistance between cephradine and methicillin-type antibiotics. (drugs.com)
  • Global (United States, European Union and China) Cephradine Market Research Report 2019-2025 report is published on June 20, 2019 and has 118 pages in it. (marketresearchreports.com)
  • In this report, 2018 has been considered as the base year and 2019 to 2025 as the forecast period to estimate the market size for Cephradine. (marketresearchreports.com)
  • Cephradine inhibits the final transpeptidation step of the peptidoglycan synthesis in bacterial cell wall by binding to one or more of the penicillinbinding proteins (PBPs), thus arresting cell wall synthesis leading to bacterial cell death. (amrospharma.com)
  • Treatment cephradine (sp? (ehealthforum.com)
  • After 48 hours administration of 100 mg/kg/day of cephradine for the treatment of otitis media, cephradine has been measured in the middle ear exudate at an average level of 3,6 micrograms/mL. (intekom.com)
  • This report studies the global market size of Cephradine, especially focuses on the key regions like United States, European Union, China, and other regions (Japan, Korea, India and Southeast Asia). (marketresearchreports.com)