OrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesInformation Science
CephalothinCephalosporinsCephaloridineCefamandoleCephapirinPhlebitisCefoxitinCefazolinMandelic AcidsMicrobial Sensitivity TestsCephalexinAmbroxolPenicillin GAnti-Bacterial AgentsCephalosporinasePenicillinaseProteusDicloxacillinEnterobacteriaceaePenicillinsStaphylococcusRolitetracyclineBacteriaMethicillinDrug Resistance, MicrobialPenicillin ResistanceAmpicillinGentamicinsbeta-LactamasesCarbenicillinEnterobacter aerogenesbeta-LactamsKlebsiellaCloxacillinTicarcillinEnterobacterOxacillinSarcinaCefadroxilBronchopneumoniaCefotaximeProteus vulgarisBacterial InfectionsAmikacinClavulanic AcidsMoxalactamKanamycinCefonicidPenicillin VDictionaries, MedicalDictionaries as TopicSodiumDictionaries, Chemical
Cephalothin
A cephalosporin antibiotic.
Cephalosporins
A group of broad-spectrum antibiotics first isolated from the Mediterranean fungus ACREMONIUM. They contain the beta-lactam moiety thia-azabicyclo-octenecarboxylic acid also called 7-aminocephalosporanic acid.
Cephaloridine
A cephalosporin antibiotic.
Cefamandole
Semisynthetic wide-spectrum cephalosporin with prolonged action, probably due to beta-lactamase resistance. It is used also as the nafate.
Cephapirin
Cephalosporin antibiotic, partly plasma-bound, that is effective against gram-negative and gram-positive organisms.
Phlebitis
Inflammation of a vein, often a vein in the leg. Phlebitis associated with a blood clot is called (THROMBOPHLEBITIS).
Cefoxitin
A semisynthetic cephamycin antibiotic resistant to beta-lactamase.
Cefazolin
A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
Mandelic Acids
Analogs or derivatives of mandelic acid (alpha-hydroxybenzeneacetic acid).
Microbial Sensitivity Tests
Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).
Cephalexin
A semisynthetic cephalosporin antibiotic with antimicrobial activity similar to that of CEPHALORIDINE or CEPHALOTHIN, but somewhat less potent. It is effective against both gram-positive and gram-negative organisms.
Ambroxol
A metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually administered as the hydrochloride.
Penicillin G
A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.
Anti-Bacterial Agents
Substances that reduce the growth or reproduction of BACTERIA.
Cephalosporinase
Penicillinase
A beta-lactamase preferentially cleaving penicillins. (Dorland, 28th ed) EC 3.5.2.-.
Proteus
A genus of gram-negative, facultatively anaerobic, rod-shaped bacteria that occurs in the intestines of humans and a wide variety of animals, as well as in manure, soil, and polluted waters. Its species are pathogenic, causing urinary tract infections and are also considered secondary invaders, causing septic lesions at other sites of the body.
Dicloxacillin
One of the PENICILLINS which is resistant to PENICILLINASE.
Enterobacteriaceae
A family of gram-negative, facultatively anaerobic, rod-shaped bacteria that do not form endospores. Its organisms are distributed worldwide with some being saprophytes and others being plant and animal parasites. Many species are of considerable economic importance due to their pathogenic effects on agriculture and livestock.
Penicillins
A group of antibiotics that contain 6-aminopenicillanic acid with a side chain attached to the 6-amino group. The penicillin nucleus is the chief structural requirement for biological activity. The side-chain structure determines many of the antibacterial and pharmacological characteristics. (Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1065)
Staphylococcus
A genus of gram-positive, facultatively anaerobic, coccoid bacteria. Its organisms occur singly, in pairs, and in tetrads and characteristically divide in more than one plane to form irregular clusters. Natural populations of Staphylococcus are found on the skin and mucous membranes of warm-blooded animals. Some species are opportunistic pathogens of humans and animals.
Rolitetracycline
A pyrrolidinylmethyl TETRACYCLINE.
Bacteria
One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.
Methicillin
One of the PENICILLINS which is resistant to PENICILLINASE but susceptible to a penicillin-binding protein. It is inactivated by gastric acid so administered by injection.
Drug Resistance, Microbial
The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).
Penicillin Resistance
Nonsusceptibility of an organism to the action of penicillins.
Ampicillin
Semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
Gentamicins
A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
beta-Lactamases
Enzymes found in many bacteria which catalyze the hydrolysis of the amide bond in the beta-lactam ring. Well known antibiotics destroyed by these enzymes are penicillins and cephalosporins.
Carbenicillin
Broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function.
Enterobacter aerogenes
Gram-negative, capsulated, gas-producing rods found widely in nature. Both motile and non-motile strains exist. The species is closely related to KLEBSIELLA PNEUMONIAE and is frequently associated with nosocomial infections
beta-Lactams
Four-membered cyclic AMIDES, best known for the PENICILLINS based on a bicyclo-thiazolidine, as well as the CEPHALOSPORINS based on a bicyclo-thiazine, and including monocyclic MONOBACTAMS. The BETA-LACTAMASES hydrolyze the beta lactam ring, accounting for BETA-LACTAM RESISTANCE of infective bacteria.
Klebsiella
A genus of gram-negative, facultatively anaerobic, rod-shaped bacteria whose organisms arrange singly, in pairs, or short chains. This genus is commonly found in the intestinal tract and is an opportunistic pathogen that can give rise to bacteremia, pneumonia, urinary tract and several other types of human infection.
Cloxacillin
A semi-synthetic antibiotic that is a chlorinated derivative of OXACILLIN.
Ticarcillin
An antibiotic derived from penicillin similar to CARBENICILLIN in action.
Enterobacter
Gram-negative gas-producing rods found in feces of humans and other animals, sewage, soil, water, and dairy products.
Oxacillin
An antibiotic similar to FLUCLOXACILLIN used in resistant staphylococci infections.
Sarcina
A genus of gram-positive, anaerobic bacteria whose organisms divide in three perpendicular planes and occur in packets of eight or more cells. It has been isolated from soil, grains, and clinical specimens.
Cefadroxil
Long-acting, broad-spectrum, water-soluble, CEPHALEXIN derivative.
Bronchopneumonia
Inflammation of the lung parenchyma that is associated with BRONCHITIS, usually involving lobular areas from TERMINAL BRONCHIOLES to the PULMONARY ALVEOLI. The affected areas become filled with exudate that forms consolidated patches.
Cefotaxime
Semisynthetic broad-spectrum cephalosporin.
Proteus vulgaris
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria that occurs in soil, fecal matter, and sewage. It is an opportunistic pathogen and causes cystitis and pyelonephritis.
Bacterial Infections
Infections by bacteria, general or unspecified.
Amikacin
A broad-spectrum antibiotic derived from KANAMYCIN. It is reno- and oto-toxic like the other aminoglycoside antibiotics.
Clavulanic Acids
Acids, salts, and derivatives of clavulanic acid (C8H9O5N). They consist of those beta-lactam compounds that differ from penicillin in having the sulfur of the thiazolidine ring replaced by an oxygen. They have limited antibacterial action, but block bacterial beta-lactamase irreversibly, so that similar antibiotics are not broken down by the bacterial enzymes and therefore can exert their antibacterial effects.
Moxalactam
Broad- spectrum beta-lactam antibiotic similar in structure to the CEPHALOSPORINS except for the substitution of an oxaazabicyclo moiety for the thiaazabicyclo moiety of certain CEPHALOSPORINS. It has been proposed especially for the meningitides because it passes the blood-brain barrier and for anaerobic infections.
Kanamycin
Antibiotic complex produced by Streptomyces kanamyceticus from Japanese soil. Comprises 3 components: kanamycin A, the major component, and kanamycins B and C, the minor components.
Cefonicid
A second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections.
Penicillin V
A broad-spectrum penicillin antibiotic used orally in the treatment of mild to moderate infections by susceptible gram-positive organisms.
Dictionaries, Medical
Dictionaries as Topic
Lists of words, usually in alphabetical order, giving information about form, pronunciation, etymology, grammar, and meaning.
Sodium
A member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.
Dictionaries, Chemical

pKa calculations for class A beta-lactamases: influence of substrate binding. (1/313)

Beta-Lactamases are responsible for bacterial resistance to beta-lactams and are thus of major clinical importance. However, the identity of the general base involved in their mechanism of action is still unclear. Two candidate residues, Glu166 and Lys73, have been proposed to fulfill this role. Previous studies support the proposal that Glu166 acts during the deacylation, but there is no consensus on the possible role of this residue in the acylation step. Recent experimental data and theoretical considerations indicate that Lys73 is protonated in the free beta-lactamases, showing that this residue is unlikely to act as a proton abstractor. On the other hand, it has been proposed that the pKa of Lys73 would be dramatically reduced upon substrate binding and would thus be able to act as a base. To check this hypothesis, we performed continuum electrostatic calculations for five wild-type and three beta-lactamase mutants to estimate the pKa of Lys73 in the presence of substrates, both in the Henri-Michaelis complex and in the tetrahedral intermediate. In all cases, the pKa of Lys73 was computed to be above 10, showing that it is unlikely to act as a proton abstractor, even when a beta-lactam substrate is bound in the enzyme active site. The pKa of Lys234 is also raised in the tetrahedral intermediate, thus confirming a probable role of this residue in the stabilization of the tetrahedral intermediate. The influence of the beta-lactam carboxylate on the pKa values of the active-site lysines is also discussed.  (+info)

Antibiotic synergy and antagonism against clinical isolates of Klebsiella species. (2/313)

Minimal inhibitory concentrations of kanamycin, gentamicin, amikacin, cephalothin, and chloramphenicol were determined in Trypticase soy broth for 70 clinical isolates of Klebsiella species. Gentamicin and amikacin were the most active on a weight basis. Chloramphenicol was more active than kanamycin, and cephalothin was the least active of all. Studies using a microtiter modification of the checkerboard technique were performed to evaluate the comparative activity of the three aminoglycosides in combination with either chloramphenicol or cephalothin. The cephalothin-aminoglycoside combinations demonstrated synergy in >80% of the isolates tested. No antagonism was noted. The chloramphenicol-aminoglycoside combinations showed antagonism in 35 to 45% of the isolates tested. The data suggest that the chloramphenicol-aminoglycoside combinations be used with caution when treating serious infections where Klebsiella is a potential pathogen.  (+info)

Transferability of cephalothin to the alveolar cavity in thoroughbreds. (3/313)

Five Thoroughbreds were classified into 4 groups according to the administration method used for saline solution (saline), ambroxol, and cephalothin sodium (cephalothin). In group A, cephalothin was injected intravenously after oral administration of ambroxol. In group B, cephalothin was injected intravenously after oral administration of saline. Groups C and D were used as control groups. The dose of cephalothin or ambroxol was clinically administrated. Venous blood and bronchoalveolar lavage fluid (BALF) were sampled from each group. In groups A and B, cephalothin concentrations in plasma reached their maximum level 5 min after cephalothin administration and then declined over time. In plasma obtained from groups A and B, there were no significant differences in pharmacokinetic parameters (T1/2, Kel, Vd). By contrast, cephalothin concentrations in BALF reached their peak at 180 min after cephalothin administration in both groups A and B and maintained a relatively high level even after 300 min. These findings indicate that cephalothin requires a relatively long period of time to move from the blood stream to the alveolar cavity, but once transferred to the alveolar cavity, it is preserved for a long time. In groups A and B, cephalothin concentrations in BALF were approximately at the same level. However, in group A, total protein in BALF was lower at 60, 180, and 300 min than the other groups. Then, cephalothin concentration was adjusted to total protein in BALF. After adjustment to total protein in BALF, group A showed a concentration level of cephalothin approximately 1.5-fold higher than that of group B. This suggests that the transferability of cephalothin to the alveolar cavity improves as a result of the oral administration of ambroxol.  (+info)

Alteration of methotrexate uptake in human leukemia cells by other agents. (4/313)

The uptake of methotrexate (MTX) and the effect of drugs known to either inhibit or enhance MTX transport in L1210 murine leukemia were studied in man using blast cells from patients with acute myelogenous leukemia in vitro. MTX uptake was found to proceed slowly, requiring at least 160 min for cells to reach a "steady state" when extracellular MTX concentrations were 1 muM. Efflux of MTX from preloaded cells required 80 to 120 min and the nonexchangeable or tightly bound fraction was 40% of the total intracellular drug. Utilizing doses that are estimates of achievable peak blood levels following single i.v. injection, cephalothin (21 mug/ml) and hydrocortisone (20 mug/ml) inhibited net MTX accumulation by 20 and 28%, respectively. Vincristine sulfate at 8.3 and 0.083 mug/ml enhanced MTX uptake by 54 and 33%, respectively, by inhibiting MTX efflux, thus increasing the level of intracellular drug in excess of the tightly bound fraction. The potential clinical implications of using MTX in combination with the aforementioned drugs for cancer chemotherapy are discussed.  (+info)

The exocellular DD-carboxypeptidase-endopeptidase of Streptomyces albus G. Interaction with beta-lactam antibiotics. (5/313)

Kinetically, the three-step model proposed for the interaction between beta-lactam antibiotics and the exocellular DD-carboxypeptidases-transpeptidases of Streptomyces R61 and Actinomadura R39 [Frere, Ghuysen & Iwatsubo (1975) Eur. J. Biochem. 57, 343--357; Fuad, Frere, Ghuysen, Duez & Iwatsubo (1976) Biochem. J. 155, 623--629] applies to the interaction between the much less penicillin-sensitive exocellular DD-carboxypeptidase-endopeptidase of Streptomyces albus G and at least phenoxymethylpenicillin, cephalothin and cephalosporin C. The penicillin resistance of the albus G enzyme is mainly due to the low efficiency with which the first reversible complex formed with the antibiotic (complex EI) undergoes transformation into a second more stable complex EI*. Analysis of the ternary interaction between enzyme, NalphaNepsilon-diacetyl-L-lysyl-D-alanyl-D-alanine (Ac2-L-Lys-D-Ala-D-Ala) and cephalosporin C indicates a non-competitive mechanism.  (+info)

Interpretive criteria for cefamandole and cephalothin disk diffusion susceptibility tests. (6/313)

A multi-center study of 1,838 clinical isolates established the accuracy of diffusion susceptibility tests with 30-mug cephalothin disks and 30-mug cefamandole disks. The same interpretive zone standards can be applied to tests with either disk but the two drugs cannot be tested interchangeably.  (+info)

Helicobacter mesocricetorum sp. nov., A novel Helicobacter isolated from the feces of Syrian hamsters. (7/313)

A spiral-shaped bacterium with bipolar, single, nonsheathed flagella was isolated from the feces of Syrian hamsters. The bacterium grew as a thin spreading film at 37 degrees C under microaerobic conditions, did not hydrolyze urea, was positive for catalase and alkaline phosphatase, reduced nitrate to nitrite, did not hydrolyze hippurate, and was sensitive to nalidixic acid but resistant to cephalothin. Sequence analysis of the 16S rRNA gene and biochemical and phenotypic criteria indicate that the novel bacterium is a helicobacter. The novel bacterium is most closely related to the recently described mouse enteric helicobacter, Helicobacter rodentium. This is the first urease-negative Helicobacter species with nonsheathed flagella isolated from feces of asymptomatic Syrian hamsters. We propose to name this novel helicobacter Helicobacter mesocricetorum. The type strain is MU 97-1514 (GenBank accession number AF072471).  (+info)

Massive pulmonary gangrene: a severe complication of Klebsiella pneumonia. (8/313)

SUMMARY: Massive pulmonary gangrene developed in two patients. Review of the literature reveals 10 other case reports of pulmonary gangrene complicating lobar pneumonia. Among the total of 12 patients whose cases have now been reported, all 4 patients who were treated nonsurgically died and the 8 who underwent surgical resection of the gangrenous lung survived. The present report emphasizes the necessity of early recognition and appropriate surgical treatment for a successful outcome.  (+info)

Cephalothin synonyms, cephalothin antonyms - FreeThesaurus.comCephalothin synonyms, cephalothin antonyms - FreeThesaurus.com
Synonyms for cephalothin in Free Thesaurus. Antonyms for cephalothin. 2 words related to cephalothin: cephalosporin, Mefoxin. What are synonyms for cephalothin?
https://www.freethesaurus.com/cephalothin
CephalothinCephalothin
Cephalothin,(6R,7R)-3-[(Acetyloxy)methyl]-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,3-(hydroxymethyl)-8-oxo-7-[2-(2-thienyl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid acetate,7-(2-thienylacetamido)cephalosporanic acid,7-(thiophene-2-acetamido)cephalosporanic acid,Sodium salt,Cephalothin, Sodium salt,Averon-1,Cefalotin,Cemastin,Cephation,Ceporacin,Cepovenin,Chephalotin,Coaxin,Keflin,Lospoven,Synclotin,Toricelocin
http://www.druglead.com/cds/cephalothin.html
Cephalothin (Keflin) for Chickens and DucksCephalothin (Keflin) for Chickens and Ducks
Cephalothin (Keflin) is a first-generation cephalosporin antiobiotic used to treat certain bacterial infections in poultry. It is used for treating gram-positive cocci, some gram-negative bacteria, and some anaerobes, including skin-related infections caused by Staphylococcus aureus.
http://www.poultrydvm.com/drugs/cephalothin
CEFALOTIN 1,0 BIOTIKA | Biotika.skCEFALOTIN 1,0 BIOTIKA | Biotika.sk
Písomná informácia pre používateľov. Informácia o použití, čítajte pozorne!. CEFALOTIN 1,0 BIOTIKA. prášok na injekčný roztok. (cefalotinum natricum). Zloženie lieku. Liečivo: Cefalotinum natricum 1,058 g zodpovedá 1,0 g cefalotinum v 1 fľaštičke.. Pomocná látka: žiadna. 1 g Cefalotinu Biotikaobsahuje 2,39 mmol sodíka.. Farmakoterapeutická skupina. Antibiotikum. Charakteristika. Širokospektrálne polosyntetické antibiotikum 1. generácie cefalosporínov určené na parenterálnu aplikáciu. Rovnako ako ostatné betalaktámové antibiotiká blokuje syntézu bunkovej steny baktérií. Je odolný voči niektorým betalaktamázam. Cefalotín veľmi dobre účinkuje proti grampozitívnym kokom vrátane streptokokov skupín A,B,C,G a ďalším, tiež pneumokokov (s výnimkou kmeňov rezistentných voči penicilínu) a stafylokokov (vrátane kmeňov produkujúcich penicilinázu, ale s výnimkou kmeňov rezistentných voči meticilínu (oxacilínu)). Z gramnegatívnych ...
http://www.biotika.sk/en/drugs/cefalotin-10-biotika
RCSB PDB - 4KOX: Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with CefalotinRCSB PDB - 4KOX: Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with Cefalotin
As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards. The RCSB PDB also provides a variety of tools and resources. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists.
https://www.rcsb.org/structure/4KOX
治療照護 - 衛生福利部疾病管制署治療照護 - 衛生福利部疾病管制署
一般可使用penicillin, ampicillin, cephalothin 和 vancomycin等抗生素治療。對於心內膜炎或敗血症的病患可同時使用penicillin和gentamicin。如能早期診斷、及時治療並給予適當的抗生素，則有復原的機會。若延遲治療患者，可能導致的毒性休克性症候群(TSS)的發生，而有生命危險。. ...
https://www.cdc.gov.tw/Category/MPage/fnrbKdAPUnmk8aYVa2s-GA
cephalothincephalothin
ceph·a·lo·thin (sĕfʹə lə thĭn) n. A semisynthetic analogue of cephalosporin having a broad spectrum of antibiotic activity that is administered parenterally and used especially to treat systemic infections caused by susceptible microorganisms. …
https://universalium.academic.ru/7489/cephalothin
ARMProgram.com Trend Top NavigationARMProgram.com Trend Top Navigation
Drugs with less than 10 isolates are removed from the chart and from the graph. The following drugs had some data removed: gatifloxacin, penicillin, piperacillin, amoxicillin, cephalothin, cefoxitin, ofloxacin, moxifloxacin. ...
http://armprogram.com/TrendCrystalReport29d9.html?Region=NATIONAL&OrganismID=10&ChartNumber=1
ARMProgram.com Trend Top NavigationARMProgram.com Trend Top Navigation
Drugs with less than 10 isolates are removed from the chart and from the graph. The following drugs had some data removed: cephalothin, moxifloxacin, clindamycin, erythromycin. ...
http://armprogram.com/TrendCrystalReport3720.html?Region=NATIONAL&OrganismID=7&ChartNumber=2
Cephalothin sodium | definition of cephalothin sodium by Medical dictionaryCephalothin sodium | definition of cephalothin sodium by Medical dictionary
Looking for online definition of cephalothin sodium in the Medical Dictionary? cephalothin sodium explanation free. What is cephalothin sodium? Meaning of cephalothin sodium medical term. What does cephalothin sodium mean?
http://medical-dictionary.thefreedictionary.com/Cephalothin+sodium
Chemoprophylaxis in cardiac and orthopedic surgery: Comparison of cephalothin and cephapirin<...Chemoprophylaxis in cardiac and orthopedic surgery: Comparison of cephalothin and cephapirin<...
TY - JOUR. T1 - Chemoprophylaxis in cardiac and orthopedic surgery. T2 - Comparison of cephalothin and cephapirin. AU - Bryant, Richard E.. AU - Hartstein, Alan I.. AU - Starr, Albert. AU - Beals, Rodney K.. PY - 1982/9. Y1 - 1982/9. N2 - In a retrospective sequential study we determined the rate of infection occurring despite cephalothin or cephapirin chemoprophylaxis in orthopedic and cardiac surgery done from 1973 to 1977. The incidence of infection after prosthetic hip placement or open reduction of hip fracture was 3.4% and 1.0% in patients receiving cephalothin or cephapirin, respectively. The infection rate after prosthetic heart valve implantation was 3.5% in those receiving cephalothin and 1.6% in those receiving cephapirin. There was no significant difference in infection rate, duration of fever 3=38.0 C, or length of postoperative hospitalization. The efficacy of selected antistaphylococcal antibiotics in preventing colonization of human fibrin clots by staphylococci was studied. ...
https://ohsu.pure.elsevier.com/en/publications/chemoprophylaxis-in-cardiac-and-orthopedic-surgery-comparison-of--2
Cephalothin sodium / cephalothin sodium NDA 062464 international drug patent coverage, generic alternatives and suppliersCephalothin sodium / cephalothin sodium NDA 062464 international drug patent coverage, generic alternatives and suppliers
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice. ...
https://www.drugpatentwatch.com/p/NDA/062464
Truform Lymphedema Compression Gauntlet: 20-30 mmHg, Small (3322BL-S) | StaplesTruform Lymphedema Compression Gauntlet: 20-30 mmHg, Small (3322BL-S) | Staples
Shop Truform Lymphedema Compression Gauntlet: 20-30 mmHg, Small (3322BL-S) at Staples. Choose from our wide selection of Truform Lymphedema Compression Gauntlet: 20-30 mmHg, Small (3322BL-S) and get fast & free shipping on select orders.
https://www.staples.com/Truform-Lymphedema-Compression-Gauntlet-20-30-mmHg-Small-3322BL-S/product_2616295
Crystallization of cephalothin sodium during lyophilization from tert-butyl alcohol-water cosolvent system<...Crystallization of cephalothin sodium during lyophilization from tert-butyl alcohol-water cosolvent system<...
TY - JOUR. T1 - Crystallization of cephalothin sodium during lyophilization from tert-butyl alcohol-water cosolvent system. AU - Telang, Chitra. AU - Suryanarayanan, Raj. N1 - Copyright: Copyright 2008 Elsevier B.V., All rights reserved.. PY - 2005/1. Y1 - 2005/1. N2 - Purpose. Because cephalothin sodium (I) does not crystallize readily when freeze-dried from aqueous solutions, organic cosolvents were used to increase the crystallinity of lyophilized I. Methods. Compound I was lyophilized from water-organic cosolvent (5% w/w) systems of each ethanol, ispropanol, and tert-butyl alcohol (TBA). Results. When frozen solutions of I (10% w/w) in each of these cosolvent systems was characterized by DSC, the presence of cosolvent in the freeze-concentrate was evident. Moreover, the presence of the cosolvent accelerated the solute crystallization. This observation was based on the XRD of these systems during the various stages of freeze-drying. High initial solute concentration and annealing of frozen ...
https://minnesota-staging.pure.elsevier.com/en/publications/crystallization-of-cephalothin-sodium-during-lyophilization-from-
Reversible Acute Renal Failure After Cephalothin | Annals of Internal Medicine | American College of PhysiciansReversible Acute Renal Failure After Cephalothin | Annals of Internal Medicine | American College of Physicians
We recently treated a patient with oliguric acute renal failure after cephalothin (Keflin®) therapy.. This 48-year-old man was referred to the M. S. Hershey Medical Center because of azotemia and oliguria. Twelve days before admission he was admitted to another hospital for right renal colic. His blood urea nitrogen (BUN) was 15 mg/dl; an intravenous pyelogram showed a normal left kidney and nonvisualization of the right kidney, with several calcific densities in the area of the right kidney. Because of fever, he was given cephalothin intravenously, 16 g/day for 8 days. On the eighth day of therapy, oliguria was noted, ...
http://annals.org/aim/article-abstract/689582/reversible-acute-renal-failure-after-cephalothin
Listeria Meningitis During Cefazolin Therapy | Annals of Internal Medicine | American College of PhysiciansListeria Meningitis During Cefazolin Therapy | Annals of Internal Medicine | American College of Physicians
Suboptimal response of meningitis to cephalothin therapy (1-2) and actual development of meningitis during cephalothin therapy (3) have been reported. We recently observed a patient who developed meningitis due to Listeria monocytogenes while he was being treated with the new cephalosporin antibiotic, cefazolin.. A 31-year-old Egyptian man with systemic lupus erythematosus and biopsy-proved lupus nephritis of the membranoproliferative type was admitted on 16 September 1974 with nephrotic syndrome and renal failure. He was treated with high dose prednisone, intermittent peritoneal dialysis, and after 10 days of hospitalization he was started on a course of nitrogen mustard. On 22 October 1974 ...
http://annals.org/aim/article-abstract/689137/listeria-meningitis-during-cefazolin-therapy
Anaphylactic Reaction to Cephalothin during Anesthesia | Anesthesiology | ASA PublicationsAnaphylactic Reaction to Cephalothin during Anesthesia | Anesthesiology | ASA Publications
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https://annals.org/aim/article-abstract/689825/cephalothin-induced-granulocytopenia
Cefoxitin, a New Semi-synthetic Cephamycin: An In-vitro and In-vivo Comparison with Cephalothin | The BMJCefoxitin, a New Semi-synthetic Cephamycin: An In-vitro and In-vivo Comparison with Cephalothin | The BMJ
Cefoxitin, a New Semi-synthetic Cephamycin: An In-vitro and In-vivo Comparison with Cephalothin Br Med J 1973; 4 :653 ... Urinary recovery of cefoxitin activity was also much higher than that of cephalothin. No evidence of toxicity due to cefoxitin ... The activity of cefoxitin was compared with that of cephalothin against 229 bacterial strains. Cefoxitin was more active ... Cefoxitin, a New Semi-synthetic Cephamycin: An In-vitro and In-vivo Comparison with Cephalothin ...
https://www.bmj.com/content/4/5893/653
Cephalothin sodium | definition of cephalothin sodium by Medical dictionaryCephalothin sodium | definition of cephalothin sodium by Medical dictionary
What is cephalothin sodium? Meaning of cephalothin sodium medical term. What does cephalothin sodium mean? ... Looking for online definition of cephalothin sodium in the Medical Dictionary? cephalothin sodium explanation free. ... cephalothin sodium. cephalothin sodium. [sef′əlō′thin] a parenteral first-generation cephalosporin antibiotic. indications It ... cephalothin sodium. (sĕf′ă-lō-thĭn″) A first-generation cephalosporin antibiotic that treats infections caused by gram-positive ...
http://medical-dictionary.thefreedictionary.com/Cephalothin+sodium
Cephaloridine and Cephalothin: Pharmacodynamics in Uremia. | Annals of Internal Medicine | American College of PhysiciansCephaloridine and Cephalothin: Pharmacodynamics in Uremia. | Annals of Internal Medicine | American College of Physicians
Cephaloridine and Cephalothin: Pharmacodynamics in Uremia. R. L. Perkins, M.D., F.A.C.P.; E. Smith, M.D.; S. Saslaw, M.D., F.A. ... Cephalothin and Cephaloridine Therapy for Bacterial Meningitis: An Evaluation Annals of Internal Medicine; 82 (5): 689-693 ... Cephaloridine and Cephalothin: Pharmacodynamics in Uremia.. Ann Intern Med. 1968;68:1175. doi: 10.7326/0003-4819-68-5-1175_3 ... Thus, the comparative pharmacodynamics of cephalothin and cephaloridine were evaluated in a crossover study in five chronically ...
http://annals.org/aim/article-abstract/682354/cephaloridine-cephalothin-pharmacodynamics-uremia
RCSB PDB - 1KVM: X-ray Crystal Structure of AmpC WT beta-Lactamase in Complex with Covalently Bound Cephalothin...RCSB PDB - 1KVM: X-ray Crystal Structure of AmpC WT beta-Lactamase in Complex with Covalently Bound Cephalothin...
... and product complexes of cephalothin with AmpC beta-lactamase. ... WT beta-Lactamase in Complex with Covalently Bound Cephalothin ...
https://www.rcsb.org/pdb/explore/macroMoleculeData.do?structureId=1KVM
Stability of Ranitidine Hydrochloride with Cefazolin Sodium, Cefbuperazone Sodium, Cefoxitin Sodium and Cephalothin Sodium...Stability of Ranitidine Hydrochloride with Cefazolin Sodium, Cefbuperazone Sodium, Cefoxitin Sodium and Cephalothin Sodium...
... cephalothin sodium and cefbuperazone sodium) during simulated Y-site injection were studied.

The mixtures were prepared by ... On the other hand, since ranitidine with cephalothin (20 mg/mL) fell below 90%, the amount of cephalothin should not exceed 10 ... except for cephalothin (86.6% of control). In the presence of 10 mg/mL cephalothin, however, ranitidine retained greater than ... Stability of Ranitidine Hydrochloride with Cefazolin Sodium, Cefbuperazone Sodium, Cefoxitin Sodium and Cephalothin Sodium ...

https://ijpc.com/abstracts/abstract.cfm?ABS=720
Cephalothin sodium / cephalothin sodium NDA 062464 international drug patent coverage, generic alternatives and suppliersCephalothin sodium / cephalothin sodium NDA 062464 international drug patent coverage, generic alternatives and suppliers
The generic ingredient in CEPHALOTHIN SODIUM is cephalothin sodium. There are seven drug master file entries for this compound ... NDA 062464 describes CEPHALOTHIN SODIUM, which is a drug marketed by Abbott, Abraxis Pharm, Bristol, and Baxter Hlthcare, and ... Additional details are available on the CEPHALOTHIN SODIUM profile page. ...
https://www.drugpatentwatch.com/p/NDA/062464
Cephalothin Sodium | elephantcareCephalothin Sodium | elephantcare
Cephalothin Sodium Injection 1 g and 2 g in 5% dextrose premixed bags in 50 ml D5W (frozen); Cephalothin Sodium® (Baxter); (Rx) ... Cephalothin Sodium Powder for Injection 1 g, 2 g in 10 ml vials and 100 ml piggyback vials and Faspak; Keflin®, Neutral (Lilly ... The following drugs or solutions are reportedly compatible with cephalothin: D25W/Amino Acids 4.25%, D5W in Lactated Ringers, ... Uses/Indications - In the United States, there are no cephalothin products approved for veterinary species, but it has been ...
http://elephantcare.org/resources/formulary/drug-index/cephalothin-sodium/
Anaphylactic Reaction to Cephalothin during Anesthesia | Anesthesiology | ASA PublicationsAnaphylactic Reaction to Cephalothin during Anesthesia | Anesthesiology | ASA Publications
Anaphylactic Reaction to Cephalothin during Anesthesia You will receive an email whenever this article is corrected, updated, ... Anaphylactic Reaction to Cephalothin during Anesthesia. Anesthesiology 10 1975, Vol.43, 476-478. doi: ... Jose L. Velazquez, Martin I. Gold; Anaphylactic Reaction to Cephalothin during Anesthesia. Anesthesiology 1975;43(4):476-478. ...
http://anesthesiology.pubs.asahq.org/article.aspx?articleid=1961190
ION-PAIR EXTRACTION AND HIGH-SPEED LIQUID CHROMATOGRAPHY OF CEPHALOTHIN AND DEACETYLCEPHALOTHIN IN HUMAN SERUM AND URINE | Drug...ION-PAIR EXTRACTION AND HIGH-SPEED LIQUID CHROMATOGRAPHY OF CEPHALOTHIN AND DEACETYLCEPHALOTHIN IN HUMAN SERUM AND URINE | Drug...
ION-PAIR EXTRACTION AND HIGH-SPEED LIQUID CHROMATOGRAPHY OF CEPHALOTHIN AND DEACETYLCEPHALOTHIN IN HUMAN SERUM AND URINE. M. J ... ION-PAIR EXTRACTION AND HIGH-SPEED LIQUID CHROMATOGRAPHY OF CEPHALOTHIN AND DEACETYLCEPHALOTHIN IN HUMAN SERUM AND URINE. M. J ... ION-PAIR EXTRACTION AND HIGH-SPEED LIQUID CHROMATOGRAPHY OF CEPHALOTHIN AND DEACETYLCEPHALOTHIN IN HUMAN SERUM AND URINE. M. J ... Cephalothin and its major metabolite, deacetylcephalothin, have been analyzed in human serum and urine using high-speed ion ...
https://dmd.aspetjournals.org/content/1/5/659
Cephalothin | Johns Hopkins ABX GuideCephalothin | Johns Hopkins ABX Guide
Cephalothin answers are found in the Johns Hopkins ABX Guide powered by Unbound Medicine. Available for iPhone, iPad, Android, ... Cephalothin is a topic covered in the Johns Hopkins ABX Guide. To view the entire topic, please sign in or purchase a ... "Cephalothin." Johns Hopkins ABX Guide, The Johns Hopkins University, 2019. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/ ... view/Johns_Hopkins_ABX_Guide/540108/all/Cephalothin. Avdic E, Pham PA. Cephalothin. Johns Hopkins ABX Guide. The Johns Hopkins ...
https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540108/all/Cephalothin
CephalothinCephalothin
... , Sodium salt,Averon-1,Cefalotin,Cemastin,Cephation,Ceporacin,Cepovenin,Chephalotin,Coaxin,Keflin,Lospoven,Synclotin ... Cephalothin,(6R,7R)-3-[(Acetyloxy)methyl]-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic ...
http://www.druglead.com/cds/cephalothin.html
cephalothincephalothin
... sodium - [USP] the monosodium salt of cephalothin, used in the treatment of infections of the major organ and ... cephalothin - Cephalosporin Ceph a*lo*spor in (s[e^]f [.a]*l[ o]*sp[=o]r [i^]n), n. [from Cephalosporium, a fungus producing ... cephalothin. ceph·a·lo·thin (sĕfʹə-lə-thĭn) n. A semisynthetic analogue of cephalosporin having a broad spectrum of antibiotic ... cephalothin - Chemically modified cephalosporin C, a broad spectrum antibiotic. * * * ceph·a·lo·thin sef ə lə (.)thin n a ...
https://universalium.academic.ru/7489/cephalothin
Nephrotoxicity Associated With Cephalothin Administration | JAMA Internal Medicine | JAMA NetworkNephrotoxicity Associated With Cephalothin Administration | JAMA Internal Medicine | JAMA Network
Variable degrees of acute renal failure developed in three patients receiving therapy with cephalothin sodium. The course and ... Nephrotoxicity Associated With Cephalothin Administration. Philip C. Carling, MD; Beldon A. Idelson, MD; A. Andrew Casano, MD; ... Nephrotoxicity Associated With Cephalothin Administration. Arch Intern Med. 1975;135(6):797-801. doi:10.1001/archinte. ... Variable degrees of acute renal failure developed in three patients receiving therapy with cephalothin sodium. The course and ...
https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/584576
Cephalothin Sodium Salt | RMICephalothin Sodium Salt | RMI
Raw Material India (RMI) is a new startup - an online platform Only For Industrial Raw Materials of all types. This is Indias First-Of-Its-Kind Exclusive B2B Raw Materials website.. ...
https://rawmaterialsindia.in/category/pharmaceuticals-drug/6507/cephalothin-sodium-salt
Cephalothin | 58-71-9Cephalothin | 58-71-9
You can also browse global suppliers,vendor,prices,Price,manufacturers of Cephalothin(58-71-9). At last,Cephalothin(58-71-9) ... Visit ChemicalBook To find more Cephalothin(58-71-9) information like chemical properties,Structure,melting point,boiling point ... Cephalothin. Product Name:. Cephalothin. CAS No.. 58-71-9. Chemical Name:. Cephalothin. CBNumber:. CB9443527. Molecular Formula ... Cephalothin sodium salt. Purity:. 96.0-101.0%. Packaging:. 1g. Price:. $111. Updated:. 2020/08/18. Buy:. Buy. Sigma-Aldrich ...
https://mip.chemicalbook.com/ChemicalProductProperty_EN_CB9443527.htm
cephalothin sodium | Tabers Medical Dictionarycephalothin sodium | Taber's Medical Dictionary
cephalothin sodium answers are found in the Tabers Medical Dictionary powered by Unbound Medicine. Available for iPhone, iPad ... cephalothin sodium is a topic covered in the Tabers Medical Dictionary. To view the entire topic, please log in or purchase a ... "Cephalothin Sodium." Tabers Medical Dictionary, 24th ed., F.A. Davis Company, 2021. Nursing Central Redesign, nursing. ... unboundmedicine.com/nursingcentral/view/Tabers-Dictionary/738334/all/cephalothin_sodium. Cephalothin sodium. In: Venes DD, ed. ...
https://nursing.unboundmedicine.com/nursingcentral/view/Tabers-Dictionary/738334/all/cephalothin_sodium
Cephalothin synonyms, cephalothin antonyms - FreeThesaurus.comCephalothin synonyms, cephalothin antonyms - FreeThesaurus.com
Antonyms for cephalothin. 2 words related to cephalothin: cephalosporin, Mefoxin. What are synonyms for cephalothin? ... cephalothin. Also found in: Dictionary, Medical, Encyclopedia, Wikipedia.. Related to cephalothin: cephalexin, cefazolin, ... Pharmacokinetics of cephalothin and cephalexin in selected avian species.. Successful treatment of a radioulnar synostosis in a ... Words related to cephalothin. a semisynthetic analogue of cephalosporin. Related Words. *cephalosporin ...
https://www.freethesaurus.com/cephalothin
Cephalothin (Keflin) for Chickens and DucksCephalothin (Keflin) for Chickens and Ducks
Cephalothin (Keflin) is a first-generation cephalosporin antiobiotic used to treat certain bacterial infections in poultry. It ... Cephalothin (Keflin). Overview Cephalothin (Keflin) is a first-generation cephalosporin antiobiotic used to treat certain ...
http://www.poultrydvm.com/drugs/cephalothin
In-vitro activity and beta-lactamase stability of methicillin, isoxazolyl penicillins and cephalothin against coagulase...In-vitro activity and beta-lactamase stability of methicillin, isoxazolyl penicillins and cephalothin against coagulase...
The inactivation of cephalothin differed from that of the other antibiotics. Type: Journal article Language: English Published ... flucloxacillin and cephalothin. The highest level of resistance was found to methicillin and the lowest to cephalothin. The ... In-vitro activity and beta-lactamase stability of methicillin, isoxazolyl penicillins and cephalothin against coagulase- ...
https://www.forskningsdatabasen.dk/en/catalog/65483427
RCSB PDB for 1IYPRCSB PDB for 1IYP
CEPHALOTHIN GROUP. C16 H18 N2 O6 S2 UUWFGEKEQSCSMB-IAQYHMDHSA-N ... Toho-1 beta-Lactamase In Complex With Cephalothin. *DOI: ...
http://www.rcsb.org/pdb/explore/king.do?structureId=1IYP
Anaphylactoid Reaction to an Initial Dose of Sodium Cephalothin | JAMA | JAMA NetworkAnaphylactoid Reaction to an Initial Dose of Sodium Cephalothin | JAMA | JAMA Network
CEPHALOTHIN, the sodium salt of 7-(thiophene2-acetamido) cephalosporanic acid, is a semisynthetic derivative of cephalosporin C ... Anaphylactoid Reaction to an Initial Dose of Sodium Cephalothin. Sherwin A. Kabins, MD; Bernard Eisenstein, MD; Sidney Cohen, ... CEPHALOTHIN, the sodium salt of 7-(thiophene2-acetamido) cephalosporanic acid, is a semisynthetic derivative of cephalosporin C ... Kabins SA, Eisenstein B, Cohen S. Anaphylactoid Reaction to an Initial Dose of Sodium Cephalothin. JAMA. 1965;193(2):165-166. ...
https://jamanetwork.com/journals/jama/article-abstract/656029
Antibiotics Tested by NARMS | NARMS | CDCAntibiotics Tested by NARMS | NARMS | CDC
Cephalothin. 2009-2012. 0.016-256†. No CLSI or NARMS breakpoints. Folate pathway antagonists. Sulfisoxazole. 2015-present. 16- ...
https://www.cdc.gov/narms/antibiotics-tested.html
Artificial gene amplification reveals an abundance of promiscuous resistance determinants in Escherichia coli | PNASArtificial gene amplification reveals an abundance of promiscuous resistance determinants in Escherichia coli | PNAS
Cephalothin. 16. 8. 2.0. bfd. 1.16 ± 0.03†. Penicillin G. 48. 32. 1.5. ...
https://www.pnas.org/content/108/4/1484/tab-figures-data
Cefalotin | Article about Cefalotin by The Free DictionaryCefalotin | Article about Cefalotin by The Free Dictionary
Related to Cefalotin: cephalothin, Keflin. cephalothin. [′sef·ə·lə·thən] (microbiology) An antibiotic derived from the fungus ... cephalothin. (redirected from Cefalotin). Also found in: Dictionary, Thesaurus, Medical, Wikipedia. ...
https://encyclopedia2.thefreedictionary.com/Cefalotin
Crystallization of cephalothin sodium during lyophilization from tert-butyl alcohol-water cosolvent system<...Crystallization of cephalothin sodium during lyophilization from tert-butyl alcohol-water cosolvent system<...
Crystallization of cephalothin sodium during lyophilization from tert-butyl alcohol-water cosolvent system. / Telang, Chitra; ... Crystallization of cephalothin sodium during lyophilization from tert-butyl alcohol-water cosolvent system. In: Pharmaceutical ... Because cephalothin sodium (I) does not crystallize readily when freeze-dried from aqueous solutions, organic cosolvents were ... Because cephalothin sodium (I) does not crystallize readily when freeze-dried from aqueous solutions, organic cosolvents were ...
https://minnesota-staging.pure.elsevier.com/en/publications/crystallization-of-cephalothin-sodium-during-lyophilization-from-
Chemoprophylaxis in cardiac and orthopedic surgery: Comparison of cephalothin and cephapirin<...Chemoprophylaxis in cardiac and orthopedic surgery: Comparison of cephalothin and cephapirin<...
Chemoprophylaxis in cardiac and orthopedic surgery: Comparison of cephalothin and cephapirin. Southern medical journal. 1982 ... Cephalothin and cephapirin have equivalent chemoprophylactic activity by clinical and microbiological criteria, permitting cost ... Cephalothin and cephapirin have equivalent chemoprophylactic activity by clinical and microbiological criteria, permitting cost ... Cephalothin and cephapirin have equivalent chemoprophylactic activity by clinical and microbiological criteria, permitting cost ...
https://ohsu.pure.elsevier.com/en/publications/chemoprophylaxis-in-cardiac-and-orthopedic-surgery-comparison-of--2
BAM Chapter 7: Campylobacter | FDABAM Chapter 7: Campylobacter | FDA
Resistance to cephalothin. R. R. R. R. S(e). S. S. a Symbols: +, 90% or more of strains are positive; -, 90% or more of strains ... e Cephalothin-resistant C. fetus subsp. fetus strains have been reported.. NOTE: C. hyointestinalis requires H2 for vigorous ... Swab an Abeyta-Hunt-Bark agar plate without antibiotics with the suspension and drop nalidixic acid and cephalothin disks onto ...
https://www.fda.gov/food/laboratory-methods-food/bam-chapter-7-campylobacter
AmpicillinAntibioticKeflinCefazolinCephapirinCefoxitinCephalosporinsCephalexinCephaloridine and CephalothinPenicillin1962AmikacinInjectionLillyResistantResistanceDicloxacillinPoorlyTherapyOralHttpsStablePatientsURINEAntibioticsSpeciesActivity
Ampicillin7
  • OY15 did show apparent resistance to ampicillin (10 [micro]g) and cephalothin (30 big) on Mueller Hinton agar during sensitivity testing. (freethesaurus.com)
  • Tzianabos reported similar results with different antibiotic classes including cephalothin , gentamicin and ampicillin/clavulanic acid. (freethesaurus.com)
  • One hundred percent of ETEC and Shigella isolates showed resistance to ampicillin, carbenicillin and cephalothin. (scirp.org)
  • The prevalence of resistance among E coli and all isolates combined was more than 20% for ampicillin, cephalothin, and sulfamethoxazole in each year studied. (nih.gov)
  • While the prevalence of resistance to trimethoprim-sulfamethoxazole, ampicillin, and cephalothin increased significantly among uropathogens causing acute cystitis, resistance to nitrofurantoin and ciprofloxacin remained infrequent. (nih.gov)
  • 75%]‎ to ampicillin, cephalothin, chloramphenicol and tetracycline. (who.int)
  • SEC plates showed good agreement with Mueller-Hinton II agar in MIC studies and can be used to screen and discriminate resistant E. coli for ampicillin, cephalothin, streptomycin, chloramphenicol, cefotaxime and gentamicin using CLSI standardized breakpoints, but not for sulphamethoxazole. (springer.com)
Antibiotic5
  • Pharmacokinetic studies in 18 volunteers showed a higher and longer sustained antibiotic activity in serum and urine after injections of cefoxitin than after equal doses of cephalothin. (bmj.com)
  • Chemistry - An injectable semi-synthetic cephalosporin antibiotic, cephalothin sodium occurs as a practically odorless, white to off-white, crystalline powder. (elephantcare.org)
  • cephalothin - Chemically modified cephalosporin C, a broad spectrum antibiotic. (academic.ru)
  • Cephalothin is a first-generation cephalosporin antibiotic used to study the mechanism of liposome encapsulated antibiotics,strategies for co-opting β-lactamases of Gram-negative bacteria for treatment of antibiotics,and for immunology studies in relation to antibiotics.It is used to study the effect of expression, binding and inhibition of penicillin-binding proteins especially PBP6 on bacterial cell wall mucopeptide synthesis. (chemicalbook.com)
  • CEPHALOTHIN, the sodium salt of 7-(thiophene2-acetamido) cephalosporanic acid, is a semisynthetic derivative of cephalosporin C, one of the naturally occurring cephalosporins, a family of antibiotics resembling the penicillins in antibiotic properties. (jamanetwork.com)
Keflin3
  • Since its introduction in 1962, cephalothin (Keflin®) has assumed a major role in the therapy of bacterial infection. (annals.org)
  • Cephalothin sodium (Keflin) occurs as a white to off-white,crystalline powder that is practically odorless. (chemicalbook.com)
  • Cephalothin (Keflin) is a first-generation cephalosporin antiobiotic used to treat certain bacterial infections in poultry. (poultrydvm.com)
Cefazolin1
  • The compatibility and stability of ranitidine hydrochloride when comixed with four cephalosporins (cefazolin sodium, cefoxitin sodium, cephalothin sodium and cefbuperazone sodium) during simulated Y-site injection were studied. (ijpc.com)
Cephapirin5
  • In a retrospective sequential study we determined the rate of infection occurring despite cephalothin or cephapirin chemoprophylaxis in orthopedic and cardiac surgery done from 1973 to 1977. (elsevier.com)
  • The incidence of infection after prosthetic hip placement or open reduction of hip fracture was 3.4% and 1.0% in patients receiving cephalothin or cephapirin, respectively. (elsevier.com)
  • The infection rate after prosthetic heart valve implantation was 3.5% in those receiving cephalothin and 1.6% in those receiving cephapirin. (elsevier.com)
  • Although cephapirin was effective at lower concentration, the activity of cephalothin and cephapirin was comparable. (elsevier.com)
  • Cephalothin and cephapirin have equivalent chemoprophylactic activity by clinical and microbiological criteria, permitting cost to be used as a basis for choosing between these antibiotics. (elsevier.com)
Cefoxitin7
  • The activity of cefoxitin was compared with that of cephalothin against 229 bacterial strains. (bmj.com)
  • Against Gram-positive organisms, however, cefoxitin was considerably less active than cephalothin, but minimum inhibitory concentrations for Staphylococcus aureus were well within therapeutically attainable blood levels. (bmj.com)
  • Urinary recovery of cefoxitin activity was also much higher than that of cephalothin. (bmj.com)
  • Cefoxitin was slightly less painful after intramuscular injection than cephalothin. (bmj.com)
  • One RCT comparing cefoxitin with cephalothin in 19 patients treated for chronic destructive pneumonia (8) had a thoracic surgeon as first author. (freethesaurus.com)
  • A randomized, double-blind, multicenter trial was initiated to compare the safety and efficacy of piperacillin, cephalothin and cefoxitin in the prophylactic treatment of patients undergoing vaginal hysterectomy. (elsevier.com)
  • A satisfactory prophylactic response was obtained in 143 of 151 (95 per cent) patients treated with piperacillin, in 82 of 87 (94 per cent) patients treated with cephalothin and in 57 of 60 (95 per cent) patients treated with cefoxitin. (elsevier.com)
Cephalosporins1
  • Cephalosporins involved in these reports included cephalothin and cephaloridine. (freethesaurus.com)
Cephalexin1
  • Pharmacokinetics of cephalothin and cephalexin in selected avian species. (freethesaurus.com)
Cephaloridine and Cephalothin1
  • Cephaloridine and Cephalothin: Pharmacodynamics in Uremia. (annals.org)
Penicillin2
  • Among the penicillin-like drugs, amoxicillin and cephalothin were the most effective in stopping bacterial growth. (freethesaurus.com)
  • This hope was strengthened by the failure to observe cross-reactions after intradermal tests with cephalosporin C in penicillin-sensitive patients 1 and by the lack of reactions following administration of cephalothin to such patients. (jamanetwork.com)
19621
  • In 1962, cephalothin and cephaloridine were introduced. (wikipedia.org)
Amikacin5
  • In vitro activity effects of combinations of cephalothin, dicloxacillin, imipenem, vancomycin and amikacin against methicillin-resistant Staphylococcus spp. (biomedcentral.com)
  • activity of dicloxacillin plus amikacin, cephalothin plus amikacin, cephalothin plus vancomycin, imipenem plus vancomycin and vancomycin plus amikacin was evaluated by checkerboard synergy tests and the fractional inhibitory concentration index (FIC) was calculated. (biomedcentral.com)
  • Results: dicloxacillin plus amikacin, and cephalothin plus amikacin were synergistic or partially synergistic in 84.6% and 100% respectively. (biomedcentral.com)
  • For nearly half of the isolates the mean concentrations of dicloxacillin, cephalothin and amikacin at which FIC indexes were calculated were achievable therapeutically. (biomedcentral.com)
  • in this study the checkerboard analysis showed that amikacin in combination with cephalothin or dicloxacillin was synergistic against most of the resistant strains of S. aureus and coagulase-negative Staphylococcus . (biomedcentral.com)
Injection1
  • After reconstituting with sterile water for injection, cephalothin sodium neutral is stable for 12 hours at room temperature and 96 hours when refrigerated. (elephantcare.org)
Lilly1
  • Literature issued December 20, 1970 on Cephalothin Discs by Eli Lilly and Co., Indianapolis, IN. (atcc.org)
Resistant1
  • Unlikeampicillin, cephalothin is resistant to penicillinase producedby S. aureus and provides an alternative to the use ofpenicillinase-resistant penicillins for the treatment of infectionscaused by such strains. (chemicalbook.com)
Resistance1
  • The highest level of resistance was found to methicillin and the lowest to cephalothin. (forskningsdatabasen.dk)
Dicloxacillin1
  • Forty-nine clinical strains of coagulase-negative staphylococci were investigated for susceptibility to methicillin, oxacillin, cloxacillin, dicloxacillin, flucloxacillin and cephalothin. (forskningsdatabasen.dk)
Poorly1
  • Cephalothin is absorbed poorly from the GI tract andmust be administered parenterally for systemic infections. (chemicalbook.com)
Therapy3
  • There have been only sporadic reports of granulocytopenia caused by cephalothin therapy (1-3). (annals.org)
  • Variable degrees of acute renal failure developed in three patients receiving therapy with cephalothin sodium. (jamanetwork.com)
  • No other causes for renal failure could be detected, and all recovered after discontinuation of cephalothin therapy, although peritoneal dialysis was required in one patient. (jamanetwork.com)
Oral1
  • Pharmacokinetics (specific) - Cephalothin is not appreciably absorbed after oral administration and must be given parenterally to achieve therapeutic serum levels. (elephantcare.org)
Https2
  • 2019. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540108/all/Cephalothin. (hopkinsguides.com)
  • 2021. https://nursing.unboundmedicine.com/nursingcentral/view/Tabers-Dictionary/738334/all/cephalothin_sodium. (unboundmedicine.com)
Stable1
  • In the frozen state, cephalothin sodium solutions are relatively stable. (elephantcare.org)
Patients1
  • Thus, the comparative pharmacodynamics of cephalothin and cephaloridine were evaluated in a crossover study in five chronically uremic patients before and during peritoneal dialysis. (annals.org)
URINE1
  • Cephalothin and its major metabolite, deacetylcephalothin, have been analyzed in human serum and urine using high-speed ion exchange liquid chromatography. (aspetjournals.org)
Antibiotics1
Species1
  • Uses/Indications - In the United States, there are no cephalothin products approved for veterinary species, but it has been used clinically in several species when a relatively short-acting, injectable, first generation cephalosporin is indicated. (elephantcare.org)
Activity1
  • Pharmacology/Spectrum of Activity - A first generation cephalosporin, cephalothin exhibits activity against the bacteria usually covered by this class. (elephantcare.org)
Cephalothin injection : Rate your experience with this treatment
Cephalothin injection : Rate your experience with this treatment (webmd.com)
Cephalothin-Induced Granulocytopenia | Annals of Internal Medicine | American College of Physicians
Cephalothin-Induced Granulocytopenia | Annals of Internal Medicine | American College of Physicians (annals.org)
Artificial gene amplification reveals an abundance of promiscuous resistance determinants in Escherichia coli | PNAS
Artificial gene amplification reveals an abundance of promiscuous resistance determinants in Escherichia coli | PNAS (pnas.org)
Laboratory Primate Newsletter, Volume 41, Number 3
Laboratory Primate Newsletter, Volume 41, Number 3 (brown.edu)
17-Ketosteroids: Reference Range, Interpretation, Collection and Panels
17-Ketosteroids: Reference Range, Interpretation, Collection and Panels (emedicine.medscape.com)
RCSB PDB - 4KOX: Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with Cefalotin
RCSB PDB - 4KOX: Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with Cefalotin (rcsb.org)
Allergic Reactions to Drugs | SpringerLink
Allergic Reactions to Drugs | SpringerLink (link.springer.com)
Antimicrobial Resistance of Escherichia coli O26, O103, O111, O128, and O145 from Animals and Humans - Volume 8, Number 12...
Antimicrobial Resistance of Escherichia coli O26, O103, O111, O128, and O145 from Animals and Humans - Volume 8, Number 12... (wwwnc.cdc.gov)
Figure 2 - Antimicrobial Resistance of Escherichia coli O26, O103, O111, O128, and O145 from Animals and Humans - Volume 8,...
Figure 2 - Antimicrobial Resistance of Escherichia coli O26, O103, O111, O128, and O145 from Animals and Humans - Volume 8,... (wwwnc.cdc.gov)
Figure 1 - Antimicrobial Resistance of Escherichia coli O26, O103, O111, O128, and O145 from Animals and Humans - Volume 8,...
Figure 1 - Antimicrobial Resistance of Escherichia coli O26, O103, O111, O128, and O145 from Animals and Humans - Volume 8,... (wwwnc.cdc.gov)
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Streptomycin use in cats | Vetlexicon Felis from Vetlexicon | Definitive Veterinary Intelligence (vetstream.com)
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Comparative Genomics of 28 Salmonella enterica Isolates: Evidence for CRISPR-Mediated Adaptive Sublineage Evolution | Journal... (jb.asm.org)
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DailyMed - ACETYLCYSTEINE solution (dailymed.nlm.nih.gov)
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Clinical Characteristics and Molecular Subtyping of Vibrio vulnificus Illnesses, Israel - Volume 14, Number 12-December 2008 -... (wwwnc.cdc.gov)
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Meningitis Lab Manual: Antimicrobial Susceptibility Testing | CDC (cdc.gov)
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Micro Drugs, Exam 1 Flashcards by Uche PM | Brainscape (brainscape.com)
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Cefalotin - encyclopedia article - Citizendium (en.citizendium.org)
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Antibiotic Panels for Susceptibility Testing: Dogs, Cats, and Other Small Animals (cvm.msu.edu)
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Eli Lilly and Company [WorldCat Identities] (worldcat.org)
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Carbapenemase-producing Enterobacteriaceae, U.S. Rivers - Volume 11, Number 2-February 2005 - Emerging Infectious Diseases... (wwwnc.cdc.gov)
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Penicillin Allergy and Other Antibiotics | SpringerLink (link.springer.com)
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October 1977 - Volume 59 - Issue 7 : JBJS (journals.lww.com)
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Acinetobacter baumannii (washoecounty.us)
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Shigella and Salmonella serogroups and their antibiotic susceptibility patterns in Ethiopia (apps.who.int)
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Coly-Mycin M Parenteral Injection : Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD (webmd.com)
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Evaluation of Petrifilm™ Select E. coli Count Plate medium to discriminate antimicrobial resistant Escherichia coli |... (rd.springer.com)
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Methotrexate (Professional Patient Advice) - Drugs.com (drugs.com)
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Pathogenic Phenotype and Genotype of Pseudomonas aeruginosa Isolates from Spontaneous Canine Ocular Infections | IOVS | ARVO... (iovs.arvojournals.org)