A cephalorsporin antibiotic.
A genus of gram-positive, anaerobic bacteria whose organisms divide in three perpendicular planes and occur in packets of eight or more cells. It has been isolated from soil, grains, and clinical specimens.
A genus of gram-negative, facultatively anaerobic, rod-shaped bacteria that occurs in the intestines of humans and a wide variety of animals, as well as in manure, soil, and polluted waters. Its species are pathogenic, causing urinary tract infections and are also considered secondary invaders, causing septic lesions at other sites of the body.
A genus of gram-negative, facultatively anaerobic, rod-shaped bacteria whose organisms arrange singly, in pairs, or short chains. This genus is commonly found in the intestinal tract and is an opportunistic pathogen that can give rise to bacteremia, pneumonia, urinary tract and several other types of human infection.
A semi-synthetic cephalosporin antibiotic.
Gram-negative gas-producing rods found in feces of humans and other animals, sewage, soil, water, and dairy products.
A group of broad-spectrum antibiotics first isolated from the Mediterranean fungus ACREMONIUM. They contain the beta-lactam moiety thia-azabicyclo-octenecarboxylic acid also called 7-aminocephalosporanic acid.
The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
A genus of gram-positive, facultatively anaerobic, coccoid bacteria. Its organisms occur singly, in pairs, and in tetrads and characteristically divide in more than one plane to form irregular clusters. Natural populations of Staphylococcus are found on the skin and mucous membranes of warm-blooded animals. Some species are opportunistic pathogens of humans and animals.
A family of gram-negative, facultatively anaerobic, rod-shaped bacteria that do not form endospores. Its organisms are distributed worldwide with some being saprophytes and others being plant and animal parasites. Many species are of considerable economic importance due to their pathogenic effects on agriculture and livestock.
A gram-positive organism found in the upper respiratory tract, inflammatory exudates, and various body fluids of normal and/or diseased humans and, rarely, domestic animals.
Inflammatory responses of the epithelium of the URINARY TRACT to microbial invasions. They are often bacterial infections with associated BACTERIURIA and PYURIA.
One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.
Detailed account or statement or formal record of data resulting from empirical inquiry.
The insertion of drugs into the rectum, usually for confused or incompetent patients, like children, infants, and the very old or comatose.
Compounds containing dibenzo-1,4-thiazine. Some of them are neuroactive.
Exclusive legal rights or privileges applied to inventions, plants, etc.
Uptake of substances through the lining of the INTESTINES.
The physical or physiological processes by which substances, tissue, cells, etc. take up or take in other substances or energy.
A phenothiazine antipsychotic used in the management of PHYCOSES, including SCHIZOPHRENIA.
The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
A genus of free-living soil amoebae that produces no flagellate stage. Its organisms are pathogens for several infections in humans and have been found in the eye, bone, brain, and respiratory tract.
Proteins obtained from ESCHERICHIA COLI.
A system for verifying and maintaining a desired level of quality in a product or process by careful planning, use of proper equipment, continued inspection, and corrective action as required. (Random House Unabridged Dictionary, 2d ed)
A basis of value established for the measure of quantity, weight, extent or quality, e.g. weight standards, standard solutions, methods, techniques, and procedures used in diagnosis and therapy.
Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).
Infections with bacteria of the species ESCHERICHIA COLI.
Glycoproteins with a molecular weight of approximately 620,000 to 680,000. Precipitation by electrophoresis is in the alpha region. They include alpha 1-macroglobulins and alpha 2-macroglobulins. These proteins exhibit trypsin-, chymotrypsin-, thrombin-, and plasmin-binding activity and function as hormonal transporters.
A novel composition, device, or process, independently conceived de novo or derived from a pre-existing model.
Property, such as patents, trademarks, and copyright, that results from creative effort. The Patent and Copyright Clause (Art. 1, Sec. 8, cl. 8) of the United States Constitution provides for promoting the progress of science and useful arts by securing for limited times to authors and inventors, the exclusive right to their respective writings and discoveries. (From Black's Law Dictionary, 5th ed, p1014)
Time period from 1701 through 1800 of the common era.
Body of knowledge related to the use of organisms, cells or cell-derived constituents for the purpose of developing products which are technically, scientifically and clinically useful. Alteration of biologic function at the molecular level (i.e., GENETIC ENGINEERING) is a central focus; laboratory methods used include TRANSFECTION and CLONING technologies, sequence and structure analysis algorithms, computer databases, and gene and protein structure function analysis and prediction.
Time period from 1601 through 1700 of the common era.
A cyclohexylamido analog of PENICILLANIC ACID.
Techniques used for determining the values of photometric parameters of light resulting from LUMINESCENCE.
The study of chemical changes resulting from electrical action and electrical activity resulting from chemical changes.
Antibodies that are chemically bound to a substrate material which renders their location fixed.
Emission of LIGHT when ELECTRONS return to the electronic ground state from an excited state and lose the energy as PHOTONS. It is sometimes called cool light in contrast to INCANDESCENCE. LUMINESCENT MEASUREMENTS take advantage of this type of light emitted from LUMINESCENT AGENTS.
A technique using antibodies for identifying or quantifying a substance. Usually the substance being studied serves as antigen both in antibody production and in measurement of antibody by the test substance.
Cyclic AMIDES formed from aminocarboxylic acids by the elimination of water. Lactims are the enol forms of lactams.
Drugs and their metabolites which are found in the edible tissues and milk of animals after their medication with specific drugs. This term can also apply to drugs found in adipose tissue of humans after drug treatment.
Substances that reduce the growth or reproduction of BACTERIA.
Lists of words, usually in alphabetical order, giving information about form, pronunciation, etymology, grammar, and meaning.
Any substances taken in by the body that provide nourishment.
The terms, expressions, designations, or symbols used in a particular science, discipline, or specialized subject area.
Changing an open-chain hydrocarbon to a closed ring. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
Inflammation of the interstitial tissue of the kidney. This term is generally used for primary inflammation of KIDNEY TUBULES and/or surrounding interstitium. For primary inflammation of glomerular interstitium, see GLOMERULONEPHRITIS. Infiltration of the inflammatory cells into the interstitial compartment results in EDEMA, increased spaces between the tubules, and tubular renal dysfunction.
Inflammation of the honeycomb-like MASTOID BONE in the skull just behind the ear. It is usually a complication of OTITIS MEDIA.
A propionic acid derivative that is used as a non-steroidal anti-inflammatory agent.
Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
Chemicals that are used to oxidize pigments and thus effect whitening.
Disease having a short and relatively severe course.
A plant genus of the family CELASTRACEAE that contains insecticidal sesquiterpenoids and celastrus oil.

The renal mitochondrial toxicity of beta-lactam antibiotics: in vitro effects of cephaloglycin and imipenem. (1/9)

The nephrotoxic beta-lactam antibiotics cephaloridine, cephaloglycin, and imipenem produce irreversible injury to renal mitochondrial anionic substrate uptake and respiration after 1 to 2 h of in vivo exposure. Toxicity during in vitro exposure is nearly identical but is immediate in onset and is reversed by the mitochondria being washed or the substrate concentrations being increased. A model of injury that accounts for these findings proposes that the beta-lactams fit carriers for mitochondrial substrate uptake, causing inhibition that is initially reversible and becomes irreversible as the antibiotics acylate the transporters. These studies were designed to create an environment of prolonged in vitro exposure, first, to determine whether toxicity becomes irreversible with time and, second, to study the molecular properties of toxicity. Respiration with and the uptake of succinate and ADP were measured in rabbit renal cortical mitochondria exposed for 2 to 6 h to 300 to 3,000 micrograms of cephalexin (nontoxic) or cephaloglycin or imipenem (nephrotoxic) per mL and then washed to remove the antibiotic. In vitro cephalexin reduced respiration only slightly and was therefore not studied further. Cephaloglycin and imipenem irreversibly reduced both respiration and succinate uptake. ADP uptake was unaffected by cephaloglycin and was slightly reduced by imipenem. Finally, cilastatin, which prevents the tubular necrosis produced by imipenem in vivo, reduced its mitochondrial toxicity in vitro. It is concluded that the pattern of in vitro injury of the nephrotoxic beta-lactams to mitochondrial substrate uptake and respiration evolves in a time-dependent and concentration-dependent manner, consistent with the proposed model of acylation and inactivation of substrate transporters, and that the protective action of cilastatin against imipenem occurs at least partly at a subcellular level.  (+info)

Enhancement of fluorescence development of end products by use of a fluorescence developer solution in a rapid and sensitive fluorescent spot test for specific detection of microbial beta-lactamases. (2/9)

A fluorescent spot test method for specific detection of microbial beta-lactamases as previously published (K. C. S. Chen, J. S. Knapp, and K. K. Holmes, J. Clin. Microbiol. 19:818-825, 1984) was improved by the use of a fluorescence developer solution. The fluorescence developer solution used in this study consisted of 0.78 M sodium tartrate buffer containing 12% formaldehyde at a final pH of 4.5. An addition of 1 volume of fluorescence developer solution to 5 volumes of ampicillin or cephalex substrate solution incubated with beta-lactamase-producing organisms, followed by heating the mixture at 45 degrees C for 10 min resulted in enhancement of fluorescence of the end products of beta-lactamase activity. This provides a more sensitive assay for microbial beta-lactamases and offers the potential for direct detection of beta-lactamases in clinical specimens.  (+info)

Inhibition of beta-lactam antibiotics at two different times in the cell cycle of Streptococcus faecium ATCC 9790. (3/9)

Treatment of Streptococcus faecium ATCC 9790 with sublytic concentrations of beta-lactam antibiotics revealed two different division blocks in the cell division cycle. One block, induced by N-formimidoyl thienamycin and methicillin, occurred before the completion of chromosome replication, whereas the other, induced by cefoxitin and cephalothin, took place later in the cycle. In addition, these antibiotics gave rise to distinct morphological forms; the antibiotics acting at the earlier block point produced mainly "dumbbells," whereas those affecting the later time formed "lemons." When used in combination N-formimidoyl thienamycin and cefoxitin exerted synergistic killing on this strain. These data suggest that beta-lactam antibiotics have at least two sites of action in S. faecium.  (+info)

Acidic degredation of cephaloglycin and high performance liquid chromatographic determination of deacetylcephaloglycin in human urine. (4/9)

In order to provide fundamental knowledge about the determination of deacetylcephaloglycin excreted in human urine as an active metabolite of cephaloglycin, the degradation of cephaloglycin in acidic media has been investigated with varying reaction temperature between 30 degrees and 50 degrees C and pH between 1.2 and 2.8. The degradation pathway observed under these conditions was the elimination of the 3-acetyl group yielding deacetylcephaloglycin followed by formation of deacetylcephaloglycin lactone. Estimation of first order rate constants revealed that deacetylation is the rate-determining step for the degradation of cephaloglycin to the lactone. It is found from the kinetic results that reproducible assays of deacetylcephaloglycin excreted in urine can be achieved by a quantitative conversion to deacetylcephaloglycin lactone in a medium of pH 1.4 at 37 degrees C for 2 hours, followed by a reversed-phase ion-pair high-performance liquid chromatography. The utility of the present method is demonstrated by determining the time course of urinary excretion of deacetylcephaloglycin after oral administration of cephaloglycin capsule.  (+info)

Differential antibiotic excretion in unilateral structural pyelonephritis. (5/9)

Differential antibiotic excretion studies in eight patients with unilateral structural pyelonephritis showed that in all instances there was impairment in antibiotic excretion on the affected side compared with the normal kidney. Both peak and mean urinary concentrations were decreased on the structurally abnormal side. The degree of defect in antibiotic concentration was proportional to the amount of unilateral medullary damage, as measured by differential renal function studies. While the antibiotic concentrations achieved had an inconsistent relationship to cure in three patients with proven unilateral infections, the striking decreases in urinary antibiotic levels may argue against oral penicillin-G treatment of unilateral pyelonephritis in which there is renal parenchymal damage.  (+info)

Chromatographic analysis and pharmacokinetic investigation of cephaloglycin and its metabolites in man. (6/9)

Metabolism and pharmacokinetics of cephaloglycin in man were investigated. High performance liquid chromatographic and gas chromatographic-mass spectrometric analyses of metabolites excreted in human urine following oral administration of cephaloglycin revealed that cephaloglycin was biotransformed in two pathways i.e. elimination of 3-acetyl group and hydrolysis of side chain amide linkage. The former yielded deacetylcephaloglycin, a part of which further underwent lactonization to deacetylcephaloglycin lactone, and the latter led to benzoyl formic acid via phenylglycine. The urinary excretion amounts of these metabolites and intact cephaloglycin were determined by a reversed phase ion pair high performance liquid chromatography. The average total excretion amounts at infinite time accounted for 0.50% of the administered dose for intact cephaloglycin, 17.09% for deacetylcephaloglycin, 0.35% for deacetylcephaloglycin lactone, and 0.86% for benzoyl formic acid. The excretion of phenylglycine was less than 0.2%, its chromatographic peak being too small to allow accurate determination. The rate constants for absorption, metabolism, and urinary excretion were estimated by the moment analysis of the excretion rate-time curves.  (+info)

Fluorimetric assay of cephradine, cephalexin and cephaloglycin. (7/9)

1 A simple, rapid and reproducible fluorimetric assay for cephradine, cephalexin and cephaloglycin is described. 2 The method involves addition of formaldehyde which catalyses the formation of fluorescent derivatives. 3 The structural similarities between the side chains of these antibiotics and their identical excitation and emission spectra suggest that they may be forming similar fluorescent derivatives.  (+info)

In vitro activities of five oral cephalosporins against aerobic pathogenic bacteria. (8/9)

Cefaclor (Lilly 99638) and cefatrizine (BL-S640, SK&F 70771) are orally absorbed, broad-spectrum semisynthetic cephalosporins. They were compared in vitro with cephalexin, cephaloglycin, and cepharadine against a variety of aerobic pathogenic bacteria by an agar dilution procedure. Cefaclor and cefatrizine were found to be similar or superior to cephalexin, cephaloglycin, and cephradine in terms of activity against gram-positive cocci other than enterococci. Only cefatrizine demonstrated any potentially useful activity against some susceptible isolates of enterococci. Cefaclor and cefatrizine also were highly active, equally or more so than the other oral cephalosporins, against several gram-negative species including Escherichia coli, Enterobacter aerogenes, and Klebsiella pneumoniae. None of the cephalosporins were particularly active against Enterobacter cloacae. Both cefaclor and cefatrizine were active against Proteus mirabilis; cefatrizine was uniquely active against indolepositive Proteus species.  (+info)

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Table salt could be used to increase the capacity of hard drives from as much as 4 Tbytes today to more than 21 Tbytes, according to researchers at the Institute of Materials Research and Engineering (IMRE). The method involves the use of a very high-resolution e-beam lithography, which is the process used to create fine nanoscale circuitry. The researchers added sodium chloride to a developer solution used in lithography processes and were able to produce highly defined nanostructures that were as small as 4.5 nm, without using expensive equipment upgrades. IMREs Joel Yang developed the salty developer solution, and worked with researchers at the National University of Singapore and the Data Storage Institute to perfect the nanopatterning technique. What we have shown is that bits can be patterned more densely together by reducing the number of processing steps, Yang says. The teams packages of bits deposited on the surface of a platter are about 10 nm in size. The researchers hope to ...
A method and device for determining the presence of an analyte in a sample suspected of containing the analyte is disclosed. The method involves contacting a test solution containing the sample and a first member of a specific binding pair with an end portion of a strip of bibulous material capable of being traversed by the test solution through capillary action. The first member of a specific binding pair is capable of binding the analyte. The strip contains a second member of a specific binding pair integral therewith for concentrating and non-diffusively binding the first sbp member at a small situs on the strip separated from the end portion of the strip. The detectible signal is produced in relation to the presence of the analyte in the test solution. The test solution passes through the situs as the test solution traverses the bibulous material. After the test solution has been allowed to traverse at least a portion of the strip, the strip is contacted with a developer solution containing members
The asymmetric hetero-Diels-Alder (HDA) reaction is among the most powerful available methodologies for the construction of optically active six-membered heterocycles, with extensive synthetic applications in natural or unnatural products with a wide range of biological activity. The DA reaction has high regioselectivity and endo-stereoselectivity. This Highlight reviews recent developments from 2005 to present (for comprehensive reviews on asymmetric DA reaction see a) Angew. Chem. Int. Ed. 2002, 41, 1650. ; b)Angew. Chem. Int. Ed. 2002, 41, 1668. ; c) Mini-Reviews in Organic Chemistry, 2004, 1, 41. Link). Some of the examples presented here use organocatalysis, which is a rapidly growing research field.. ...
[65 Pages Report] Check for Discount on cephaloglycin Global Market and Forecast Research report by ChemReport. DescriptionWe provide independent and unbiased information on manufacturers, prices, production...
a) Fixer (10% acetic acid) Add 50 ml glacial acetic acid to 450 ml distilled water b) Silver stain Add 3 ml 1N silver nitrate solution in 500 ml distilled water. Then add 0.75ml formamide c) Developer Dissolve 15 g sodium carbonate in 500 ml distilled water and put at 4 O C 1. Remove the gel and separate the plates carefully with a single-edged razor blade. 2. Place the gel in tray with the fixer and leave shaking in a fume hood for 30 minutes. Pour off fixer (save). 3. Wash with water for 10 15 minutes, on shaker. Rinse again and pour off the water. 4. Add silver-stain and leave shaking for 30 minutes (Silver stain can be re-used up to 10 times). 5. Immediately before developing the gel, add in 75 m l sodium thiosulphate solution (0.1N) and 0.75 ml formamide to the pre-chilled developer solution. 6. After silver-stain (step 4), agitate the gel several times for 10 seconds. 7. Immediately agitate the gel in the developer until band development progress sufficiently. 8. Stop the reaction by ...
Dear HistoNetters Happy Holidays! Heres a nice microwave version of the Bodian Stain, courtesy of Dr. Mathilde Boon: The Bodian silver stain is used to color neurofibrils, unmyelinated and myelinated nerve fibers. SOLUTIONS NEEDED: Protargol solution: 0.5 g Protargol 3.0 g Metallic Copper Shot 50 ml Distilled water NOTE: Prepare the solution immediately before use. Developer solution: 1 g Hydroquinone (C6H6O2) 50 ml Distilled water 2.5 ml 37% formalin (CH2O) NOTE: Prepare the solution immediately before use. Gold Chloride solution: 1 g Gold (III) Chloride (HAuCl4 H2O, 49% pure) 100 ml Distilled water 3 drops Glacial Acetic acid Oxalic Acid solution: 1 g Oxalic acid dihydrate (C2H2O4 2H2O) 50 ml Distilled water Sodium Thiosulfate solution: 5 g Sodium Thiosulfate (Na2S2O3 5H2O) 50 ml Distilled water PROCEDURE: 1. Deparaffinize and bring to water 2. 60 min / 37 C in conventional incubation / 50 ml of Protargol solution 3. 60 min / 60 C / same Protargol solution 4. Rinse well in distilled water 5. ...
To understand, how hair dyes work - you first need to know about the hair anatomy.. Hair comprises of three layers - medulla, cortex, and cuticle.. The core layer is called the medulla.. Cortex is surrounded by a thick layer of cells. It is responsible for pigmentation and melanin.. The cuticle is the outer layer that protects your hair.. Along with hair anatomy, you also need to know three types of hair dye - temporary, semi-permanent, and permanent hair dye.. When you apply temporary hair dye, it will just stick to the outer layer of the hair, i.e. cuticle. Due to it, the colour will vanish instantly after shampooing.. Whereas semi-permanent hair dye contains molecules that can slip between the cuticle and can stick to the cortex. As a result, it wont vanish easily even after shampooing. It will last for about 12 shampoos.. Permanent hair dye stays with your hair until it grows and falls out.. It contains two solutions alkaline and developers( Solution of hydrogen peroxide).. You mix both ...
4. Photographic Industries: It is mostly used in photographic industries for production of developer solution/acidizing fixation baths.. 5. Pulp and Textiles: It is used as a bleaching agent in pulp and textile industries.. 6. Rubber Industries: It is used as coagulative agnet for rubber industries.. 7. Acrylic Fibres : Chemical synthesis in manufacturing of Acrylic fibres and Acrylic sheets.. 8. Dye Industries : It acts as dechlorination agent in dye industries.. 9. Gold Mining Industries : It is used in Mining industries as floating agent ...
With the implementation of the Food and Drug Administrations Food Safety Modernization Act, the food industry must scientifically verify that current production processes provide sufficient protection against pathogens. This study was conducted to validate a simulated commercial baking process for hamburger buns to control Salmonella spp. contamination and to determine the appropriateness of using non-pathogenic surrogates (Enterococcus faecium ATCC 8459 or Saccharomyces cerevisiae) for in-plant process validation studies. Wheat flour was separately inoculated (~6 log CFU/g) with three Salmonella serovars (Typhimurium, Newport or Senftenberg) or E. faecium. Dough was formed, proofed, and baked to mimic commercial manufacturing conditions. Non-inoculated dough was used to evaluate S. cerevisiae (Bakers yeast) survival during baking. Buns were baked for 9, 11 and 13 min in a conventional oven set at 218°C, with internal bun temperature profiles recorded. Salmonella serovars and S. cerevisiae ...
A primary objective of this study was to characterize the budding of retroviruses in real time in vivo. Although entry of single HIV-1 particles has been imaged in live cells (19), we are not aware of similar studies on budding of single particles. We have shown that VLPs bud one at a time from the plasma membrane, occasionally from the same site. Correlated fluorescence microscopy and SEM imaging demonstrated that Gag-GFP can be incorporated into morphologically correct structures in the presence of excess untagged Gag and that a large fraction of the fluorescent spots observed by MPM correspond with properly assembled VLPs.. It has often been assumed that Gag-GFP properly carries out all of the functions of untagged Gag (4, 9-11, 15). Early evidence suggested that, by itself, RSV Gag-GFP formed particles with normal morphology (10). However, from more recent data (Rebecca Craven, personal communication), such particles seem to have heterogeneous sedimentation coefficients, consistent with the ...
The fluorescent two-hybrid assay (F2H) is a technique for the validation and characterization of protein-protein interactions in vivo. It can be used for studying the modulation of interactions with inhibitors or activators, for compound screening and for confirmation of results from other protein-protein interaction screens such as co-immunoprecipitation studies.. In short, two proteins, bait and prey protein, are fused to GFP and RFP, respectively. A BHK cell line is transformed with ChromoTeks F2H platform reagent and two DNA plasmids coding for the GFP-bait protein and the RFP-prey protein. The interaction of bait protein and prey protein can be detected by co-localization of a green and a red fluorescent spot in the nucleus of the BHK cells with an epi-fluorescence microscope.. PRODUCTS ...
The fluorescent two-hybrid assay (F2H) is a technique for the validation and characterization of protein-protein interactions in vivo. It can be used for studying the modulation of interactions with inhibitors or activators, for compound screening and for confirmation of results from other protein-protein interaction screens such as co-immunoprecipitation studies.. In short, two proteins, bait and prey protein, are fused to GFP and RFP, respectively. A BHK cell line is transformed with ChromoTeks F2H platform reagent and two DNA plasmids coding for the GFP-bait protein and the RFP-prey protein. The interaction of bait protein and prey protein can be detected by co-localization of a green and a red fluorescent spot in the nucleus of the BHK cells with an epi-fluorescence microscope.. PRODUCTS ...
Book MP Antigen Spot test Blood @Home at Best Prices at the slot of your choice. View details of test: When to take, What is the normal range & Get reports Online.
Consult a professional prior to cleaning. For ordinary cleaning, use mild soap and water. For more severe soiling, remove promptly with a non-abrasive cleaner. Gently lift any remaining spill to avoid further staining. Rub gently and rinse with water dampened cloth to remove cleaner concentration. Kindly spot test an area before cleaning. ...
The IUPHAR/BPS Guide to Pharmacology. cephradine ligand page. Quantitative data and detailed annnotation of the targets of licensed and experimental drugs.
VOLVOCEF (Cephradine) is a first-generation cephalosporin antibacterial given orally and by parenteral route in the treatment of susceptible infections and
The information contained herein has been obtained from sources that the Company believes to be reliable, however, the Company has not independently verified or confirmed the information and the recipient acknowledges that no representations or warranties are being made in connection with the use of the information.. ...
Consult a professional prior to cleaning. For ordinary cleaning, use mild soap and water. For more severe soiling, remove promptly with a non-abrasive cleaner. Gently lift any remaining spill to avoid further staining. Rub gently and rinse with water dampened cloth to remove cleaner concentration. Kindly spot test an area before cleaning. ...
Pill with imprint biocraft 113 is Green, Capsule-shape and has been identified as Cephradine 500 MG. It is supplied by Teva Pharmaceuticals USA.
Purified Universal Kinase Fluorometric Assay Kit from Creative Biomart. Universal Kinase Fluorometric Assay Kit can be used for research.
Purified LDH-Cytotoxicity Fluorometric Assay Kit from Creative Biomart. LDH-Cytotoxicity Fluorometric Assay Kit can be used for research.
Enterococcus faecium ATCC ® 8459™ Designation: NCTC 2699 TypeStrain=False Application: Produces FAD flavin-adenine dinucleotide
Sodium Sulfide Spot Test Definition - A sodium sulfide spot test is a localized chemical test to detect any concentration of lead in a coating...
Quantitative microscopy deals with the extraction of quantitative measurements from samples observed under a microscope. Recent developments in microscopy systems, sample preparation and handling techniques have enabled high throughput biological experiments resulting in large amounts of image data, at biological scales ranging from subcellular structures such as fluorescently tagged nucleic acid sequences to whole organisms such as zebrafish embryos. Consequently, methods and algorithms for automated quantitative analysis of these images have become increasingly important. These methods range from traditional image analysis techniques to use of deep learning architectures.. Many biomedical microscopy assays result in fluorescent spots. Robust detection and precise localization of these spots are two important, albeit sometimes overlapping, areas for application of quantitative image analysis. We demonstrate the use of popular deep learning architectures for spot detection and compare them ...
Technology Networks is an internationally recognised publisher that provides access to the latest scientific news, products, research, videos and posters.
A method is provided to fluorometrically determine a ligand in an assay solution containing the ligand, reagent system and a fluorescer wherein the intensity of the fluorescer emitted by the assay sol
6-thio-dG induces persistent telomere damage in conjunction with extensive genomic DNA damage in telomerase-positive cells several days after drug withdrawal. This is detail of an image of HFF + hTERT cells stained by FISH-immunofluorescence using a telomere specific PNA probe (red) and γH2AX staining (green). Yellow fluorescent spots indicate co-localization of DNA damage (γH2AX) and telomere signal (TelC). ...
Fructose Colorimetric/Fluorometric Assay Kit; Compatible with high-throughput handling systems. Bulk and Prepack available at Sigmaaldrich.com.
Renin Activity Fluorometric Assay Kit: simple, rapid & convenient method to detect renin activity as low as 0.75 U/ml. 100 assays.
Through the Drug Development Solutions Center, we offer a Glu/Gal Mitochondrial Toxicity in vitro study to evaluate your drugs DILI risk.
MMP-9 Inhibitor Screening Kit (Fluorometric): A Fluorometric Assay Kit to screen/study/charecterize MMP-9 inhibitors easily. 100 assays
Discussing recycled conference talks and developers who stop learning after 5pm (when they come home from work). Are you one of them? Can they ever be good?
13. jouluta 2017 - Koko talo/asunto hintaan 108€. Natural hot spring waters to bathe in and at your privacy, for up to 20 pax. For 12-hour use only. There are two units available for your exclusiv...
Plasmodium vivax malaria elimination can only be achieved by the deployment of 8-aminoquinolines (primaquine and tafenoquine) in combination with ACT to kill both blood and liver-stage parasites. However, primaquine and the other 8-aminoquinolines cause dose-dependent haemolysis in subjects with G6PD deficiency, an X-linked disorder of red blood cells that is very common in populations living in tropical and subtropical areas. In order to inform safer use of 8-aminoquinolines in the Greater Mekong Subregion, a multi-centre study was carried out to assess the prevalence of G6PD deficiency and to identify the main G6PD variants in samples collected in Cambodia, Lao PDR, Myanmar, Thailand and Vietnam. Blood samples were collected in the five countries during National Malaria Surveys or during Population Surveys. During Population Surveys samples were characterized for G6PD phenotype using the Fluorescent Spot Test. Samples were then genotyped for a panel of G6PD mutations. G6PD deficiency was found to be
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A myosin heavy chain polypeptide has been identified and localized in Nicotiana pollen tubes using monoclonal anti-myosin antibodies. The epitopes of these antibodies were found to reside on the myosin heavy chain head and rod portion and were, therefore, designated anti-S-1 (myosin S-1) and anti-LMM (light meromyosin). On Western blots of the total soluble pollen tube proteins, both anti-S-1 and anti-LMM label a polypeptide of approximately 175,000 Mr. Immunofluorescence microscopy shows that both antibodies yield numerous fluorescent spots throughout the whole length of the tube, often with an enrichment in the tube tip. These fluorescent spots are thought to represent vesicles and/or organelles in the pollen tubes. In addition to this common pattern, anti-S-1 stains both the generative cell and the vegetative nuclear envelope. The different staining patterns of the nucleus between anti-S-1 and anti-LMM may be caused by some organization and/or anchorage state of the myosin molecules on the ...
Cephradine (Eskacef - SKF; Velosef - Squibb) is a new semi-synthetic cephalosporin for oral use. Like other cephalosporins it is active against both Gram-negative and Gram-positive pathogens, apparently including penicillinase-producing staphylococci (though this has been questioned1). It is advertised as having new striking power, but from the data provided its spectrum of activity closely resembles that of cephalexin (Ceporex - Glaxo; Keflex - Lilly),2 and the promotional literature on cephradine makes no direct comparison between the two drugs.. ...
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A method for loading a replenishment developer into a developer accommodating container such that when the replenishment of the replenishment developer inside the loaded developer accommodating contai
Is Rash Pruritic a common side effect of Cephalexin? View Rash Pruritic Cephalexin side effect risks. Female, 15 years of age, weighting 121.3 lb, took Cephalexin Unk. Patient was hospitalized.
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Tune B, Hsu C (1990). "The renal mitochondrial toxicity of beta-lactam antibiotics: in vitro effects of cephaloglycin and ... A comparative study of cephaloridine and cephaloglycin". Biochem Pharmacol. 38 (5): 795-802. doi:10.1016/0006-2952(89)90233-5. ... Cefaloglycin INN (also spelled cephaloglycin) is a first-generation cephalosporin antibiotic. ...
... a comparison of cephaloridine and cephaloglycin". Kidney International. 18 (5): 591-600. doi:10.1038/ki.1980.177. PMID 7463955 ...
... cephaloglycin), and in 1973 Kefzol (cefazolin). Lilly had patents on all its cephalosporin antibiotics except Kefzol (cefazolin ...
... cephaloglycin MeSH D02.065.589.099.249.200.185 - cephradine MeSH D02.065.589.099.249.210 - cephaloridine MeSH D02.065.589.099. ...
65 Pages Report] Check for Discount on cephaloglycin Global Market and Forecast Research report by ChemReport. DescriptionWe ... The price of cephaloglycin in 2016 Major end users of cephaloglycin Potential users of cephaloglycin The main trading companies ... cephaloglycin Global Market and Forecast Research Table of Contents Part 1: General Information of cephaloglycin Chapter 1: ... 2.2 Construction of Industry Chain of cephaloglycin Chapter 3: End User of cephaloglycin List of Tables Manufacturers and ...
A method and drug form enhancing the rate of absorption of a rectally administered drug from the rectal compartment into the blood stream of a warm blooded animal. The method includes the steps of preparing a drug form capable of being rectally administered. The drug form comprises a therapeutically effective unit dosage amount of a selected drug of the type which is capable of being absorbed into the blood stream from the rectal compartment and phenothiazines or salts thereof being present in the drug form in a sufficient amount to be effective in enhancing the drug absorption rate, when rectally administering the drug form to warm blooded animals.
Assay of cefamandole Assay of cefazolin Assay of cefotaxime Assay of cefoxitin Assay of cephalexin Assay of cephaloglycin Assay ... Assay of cephaloglycin. Assay of cephaloridine cephalomycin. Enteric Research. Assay of cephalothin. Assay of cephapirin. Assay ...
... capromycin Assay of cefamandole Assay of cefoxitin Assay of cephaloglycin Assay of cephaloridine cephalomycin Assay of ... Assay of cephaloglycin. Assay of cephaloridine cephalomycin. Assay of cephalothin. Assay of dihydrostreptomycin sulfate ...
Cephaloglycin View Synonyms. View Structure. Description:. A cephalorsporin antibiotic. Categories:. * Info Anti-Bacterial ...
Susceptibility disc testing cephalexin ref Susceptibility disc testing cephaloglycin ref Susceptibility disc testing kanamycin ... Susceptibility disc testing cephaloglycin Ref. . . Literature issued December 20, 1970 on Cephalothin Discs by Eli Lilly and Co ...
Cephaloglycin. approved. unknown. inhibitor. Details. DB00125. L-Arginine. approved, nutraceutical. unknown. inhibitor. Details ...
14C-cephalexin and 14C-cephaloglycin: comparative intestinal absorption and biliary excretion.. Halpin TC Jr, Perkins RL, ...
Stillerman M (1970) Comparison of cephaloglycin and penicillin in streptococcal pharyngitis. Clin Pharmacol Ther 11:205-213 ...
The E. C. G. and Pathoanatomical Findings of the Heart (V) Observation by Post Mortem Roentgengraphic Technic of Coronary Artery and Serial Gross Frozen Sectionning of the Entire Heart (1963 ...
Tune B, Hsu C (1990). "The renal mitochondrial toxicity of beta-lactam antibiotics: in vitro effects of cephaloglycin and ... A comparative study of cephaloridine and cephaloglycin". Biochem Pharmacol. 38 (5): 795-802. doi:10.1016/0006-2952(89)90233-5. ... Cefaloglycin INN (also spelled cephaloglycin) is a first-generation cephalosporin antibiotic. ...
Cephaloglycin; Cephaloridine; Cephalothin Sodium; Cephapirin Sodium; Cephradine; Cetocycline Hydrochloride; Cetophenicol; ...
Cephaloglycin; Cephaloridine; Cephalothin Sodium; Cephapirin Sodium; Cephradine;.Cetocycline Hydrochloride; Cetophenicol; ...
CLINICAL EVALUATION OF CINOXACIN IN COMPLICATED URINARY TRACT INFECTIONS:A COMPARATIVE STUDY WITH NALIDIXIC ACID BY A RANDOMIZED DOUBLE BLIND METHOD (1980 ...
... cefadroxil and cephaloglycin. The change in the ability to fluoresce is attributed to the presence of β-lactamase. ...
... a comparison of cephaloridine and cephaloglycin". Kidney International. 18 (5): 591-600. doi:10.1038/ki.1980.177. PMID 7463955 ...
KAFOCIN (CEPHALOGLYCIN) KAINAIR (PROPARACAINE HYDROCHLORIDE) KALETRA (LOPINAVIR; RITONAVIR) KANAMYCIN (KANAMYCIN SULFATE) ...
14325888 - In vitro and in vivo laboratory evaluation of cephaloglycin and cephaloridine.. 16346628 - Formation and ...
1980) Mechanisms of cephalosporin nephrotoxicity: a comparison of cephaloridine and cephaloglycin. Kidney Int 18:591-600. ...
... or cephaloglycin; chloramphenicols; macrolides, such as erythromycin, tylosin, oleandomycin, or spiramycin; penicillins, such ...
... cephaloglycin, and cephalothin) (Lin et al., 1999) and nonsteroidal anti-inflammatory drugs (Mulato et al., 2000), which have ...
The group includes cefadroxil monohydrate, cefamandole nafate, cefazolin, cephalexin, cephaloglycin, cephaloridine, cephalothin ...
Cephaloglycin(Antibacterial.). *Cephalonic Acid. *Cephalonium. *Cephaloridine(Antibacterial.). *Cephalosporin C(Antibacterial.) ...
Noun 1. Kafocin - antibiotic related to cephalosporin but no longer in common use cephaloglycin antibiotic, antibiotic drug - a ... cephaloglycin. antibiotic, antibiotic drug - a chemical substance derivable from a mold or bacterium that can kill ...
The group includes cefadroxil monohydrate, cefamandole nafate, cefazolin, cephalexin, cephaloglycin, cephaloridine, cephalothin ...
Bundgaard, H. (1976) Hydrolysis and intramolecular aminolysis of cephalexin and cephaloglycin in aqueous solution, Arch. Pharm ...
Cephaloglycin. Cephaloram. Cephaloridine. Cephalosporins; its salts; its esters; their salts, that is to say, the antimicrobial ...
Pyrogram of cephaloglycin.. TIME (MINUTES). Figure 23. Pyrogram of cefazolin.. RESPONSE. Figure 24.. Pyrogram of cephalothin.. ... Peak identification in cephaloglycin pyrogram.. RESPONSE. Figure 35.. Peak identification in cephalothin pyrogram.. RELATIVE ... cephaloglycin (Figure 22) consistently appeared at a slightly. greater intensity in the pyrogram of the latter. However,. ... cephaloglycin (Figure 22) consistently appeared at a slightly. greater intensity in the pyrogram of the latter. However,. ...
Because of this homology, and evidence of a role of lipids in cephaloglycin (Cgl) nephrotoxicity, protocols were designed to ...
Tune BM, Fravert D. Mechanisms of cephalosporin nephrotoxicity: a comparison of cephaloridine and cephaloglycin. Kidney Int. ... Transport, cytotoxicity and mitochondrial toxicity of cephaloglycin. J Pharmacol Exp Ther. 1980;215(1):186-90. ...
  • Among the semisynthetic ones are cephaloridine (Ceporin), cephalothin, cefazolin, cephalexin, cephradine, and cephaloglycin, all of which are used in the treatment of infectious diseases caused by microorganisms sensitive to these antibiotics. (thefreedictionary.com)
  • It has subsequently introduced four additional cephalosporin forms: Keflex (cephalexin), Loridine (cephaloridine), Kafocin (cephaloglycin), and Kefzol (cefazolin). (findacase.com)
  • 14C-cephalexin and 14C-cephaloglycin: comparative intestinal absorption and biliary excretion. (nih.gov)
  • Cefaloglycin INN (also spelled cephaloglycin) is a first-generation cephalosporin antibiotic. (wikipedia.org)
  • 442.21 Cephaloglycin dihydrate. (google.lv)
  • 442.121a Cephaloglycin dihydrate capsules. (google.lv)