Hepatic Veins: Veins which drain the liver.Liver: A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.Veins: The vessels carrying blood away from the capillary beds.Catheterization, Central Venous: Placement of an intravenous CATHETER in the subclavian, jugular, or other central vein.Portal Vein: A short thick vein formed by union of the superior mesenteric vein and the splenic vein.Liver Circulation: The circulation of BLOOD through the LIVER.Jugular Veins: Veins in the neck which drain the brain, face, and neck into the brachiocephalic or subclavian veins.Subclavian Vein: The continuation of the axillary vein which follows the subclavian artery and then joins the internal jugular vein to form the brachiocephalic vein.Brachiocephalic Veins: Large veins on either side of the root of the neck formed by the junction of the internal jugular and subclavian veins. They drain blood from the head, neck, and upper extremities, and unite to form the superior vena cava.Budd-Chiari Syndrome: A condition in which the hepatic venous outflow is obstructed anywhere from the small HEPATIC VEINS to the junction of the INFERIOR VENA CAVA and the RIGHT ATRIUM. Usually the blockage is extrahepatic and caused by blood clots (THROMBUS) or fibrous webs. Parenchymal FIBROSIS is uncommon.Hepatic Artery: A branch of the celiac artery that distributes to the stomach, pancreas, duodenum, liver, gallbladder, and greater omentum.Femoral Vein: The vein accompanying the femoral artery in the same sheath; it is a continuation of the popliteal vein and becomes the external iliac vein.Saphenous Vein: The vein which drains the foot and leg.Phlebography: Radiographic visualization or recording of a vein after the injection of contrast medium.Varicose Veins: Enlarged and tortuous VEINS.Vena Cava, Inferior: The venous trunk which receives blood from the lower extremities and from the pelvic and abdominal organs.Hepatectomy: Excision of all or part of the liver. (Dorland, 28th ed)Venous Cutdown: Creation of a small incised opening in a vein to permit the passage of a needle or cannula for withdrawal of blood, administration of medication, or in diagnostic or therapeutic catheterization. (Dorland, 28th ed.; Stedman, 26th ed.)Arteriovenous Shunt, Surgical: Surgical shunt allowing direct passage of blood from an artery to a vein. (From Dorland, 28th ed)Axillary Vein: The venous trunk of the upper limb; a continuation of the basilar and brachial veins running from the lower border of the teres major muscle to the outer border of the first rib where it becomes the subclavian vein.Upper Extremity Deep Vein Thrombosis: DEEP VEIN THROMBOSIS of an upper extremity vein (e.g., AXILLARY VEIN; SUBCLAVIAN VEIN; and JUGULAR VEINS). It is associated with mechanical factors (Upper Extremity Deep Vein Thrombosis, Primary) secondary to other anatomic factors (Upper Extremity Deep Vein Thrombosis, Secondary). Symptoms may include sudden onset of pain, warmth, redness, blueness, and swelling in the arm.Pulmonary Veins: The veins that return the oxygenated blood from the lungs to the left atrium of the heart.Catheters, Indwelling: Catheters designed to be left within an organ or passage for an extended period of time.Hepatic Veno-Occlusive Disease: Liver disease that is caused by injuries to the ENDOTHELIAL CELLS of the vessels and subendothelial EDEMA, but not by THROMBOSIS. Extracellular matrix, rich in FIBRONECTINS, is usually deposited around the HEPATIC VEINS leading to venous outflow occlusion and sinusoidal obstruction.Constriction, Pathologic: The condition of an anatomical structure's being constricted beyond normal dimensions.Mesenteric Veins: Veins which return blood from the intestines; the inferior mesenteric vein empties into the splenic vein, the superior mesenteric vein joins the splenic vein to form the portal vein.Living Donors: Non-cadaveric providers of organs for transplant to related or non-related recipients.Vena Cava, Superior: The venous trunk which returns blood from the head, neck, upper extremities and chest.Liver Transplantation: The transference of a part of or an entire liver from one human or animal to another.Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.Central Venous Catheters: Catheters that are inserted into a large central vein such as a SUBCLAVIAN VEIN or FEMORAL VEIN.Thrombophlebitis: Inflammation of a vein associated with a blood clot (THROMBUS).Renal Veins: Short thick veins which return blood from the kidneys to the vena cava.Liver Neoplasms: Tumors or cancer of the LIVER.Hepatocytes: The main structural component of the LIVER. They are specialized EPITHELIAL CELLS that are organized into interconnected plates called lobules.Renal Dialysis: Therapy for the insufficient cleansing of the BLOOD by the kidneys based on dialysis and including hemodialysis, PERITONEAL DIALYSIS, and HEMODIAFILTRATION.Umbilical Veins: Venous vessels in the umbilical cord. They carry oxygenated, nutrient-rich blood from the mother to the FETUS via the PLACENTA. In humans, there is normally one umbilical vein.Iliac Vein: A vein on either side of the body which is formed by the union of the external and internal iliac veins and passes upward to join with its fellow of the opposite side to form the inferior vena cava.Liver Diseases: Pathological processes of the LIVER.Parietal Lobe: Upper central part of the cerebral hemisphere. It is located posterior to central sulcus, anterior to the OCCIPITAL LOBE, and superior to the TEMPORAL LOBES.Hepatic Encephalopathy: A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)Superior Vena Cava Syndrome: A condition that occurs when the obstruction of the thin-walled SUPERIOR VENA CAVA interrupts blood flow from the head, upper extremities, and thorax to the RIGHT ATRIUM. Obstruction can be caused by NEOPLASMS; THROMBOSIS; ANEURYSM; or external compression. The syndrome is characterized by swelling and/or CYANOSIS of the face, neck, and upper arms.Popliteal Vein: The vein formed by the union of the anterior and posterior tibial veins; it courses through the popliteal space and becomes the femoral vein.Cerebellar Cortex: The superficial GRAY MATTER of the CEREBELLUM. It consists of two main layers, the stratum moleculare and the stratum granulosum.Hepatic Stellate Cells: Perisinusoidal cells of the liver, located in the space of Disse between HEPATOCYTES and sinusoidal endothelial cells.Cerebellum: The part of brain that lies behind the BRAIN STEM in the posterior base of skull (CRANIAL FOSSA, POSTERIOR). It is also known as the "little brain" with convolutions similar to those of CEREBRAL CORTEX, inner white matter, and deep cerebellar nuclei. Its function is to coordinate voluntary movements, maintain balance, and learn motor skills.Vascular Patency: The degree to which BLOOD VESSELS are not blocked or obstructed.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Hypertension, Portal: Abnormal increase of resistance to blood flow within the hepatic PORTAL SYSTEM, frequently seen in LIVER CIRRHOSIS and conditions with obstruction of the PORTAL VEIN.Portal System: A system of vessels in which blood, after passing through one capillary bed, is conveyed through a second set of capillaries before it returns to the systemic circulation. It pertains especially to the hepatic portal system.Anastomosis, Surgical: Surgical union or shunt between ducts, tubes or vessels. It may be end-to-end, end-to-side, side-to-end, or side-to-side.Splenic Vein: Vein formed by the union (at the hilus of the spleen) of several small veins from the stomach, pancreas, spleen and mesentery.Venae Cavae: The inferior and superior venae cavae.Ultrasonography, Doppler: Ultrasonography applying the Doppler effect, with frequency-shifted ultrasound reflections produced by moving targets (usually red blood cells) in the bloodstream along the ultrasound axis in direct proportion to the velocity of movement of the targets, to determine both direction and velocity of blood flow. (Stedman, 25th ed)Reconstructive Surgical Procedures: Procedures used to reconstruct, restore, or improve defective, damaged, or missing structures.Magnetic Resonance Imaging: Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.Venous Pressure: The blood pressure in the VEINS. It is usually measured to assess the filling PRESSURE to the HEART VENTRICLE.Cerebral Veins: Veins draining the cerebrum.Vascular Surgical Procedures: Operative procedures for the treatment of vascular disorders.Tissue and Organ Harvesting: The procedure of removing TISSUES, organs, or specimens from DONORS for reuse, such as TRANSPLANTATION.Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.Splanchnic Circulation: The circulation of blood through the BLOOD VESSELS supplying the abdominal VISCERA.Brain Mapping: Imaging techniques used to colocalize sites of brain functions or physiological activity with brain structures.Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents.Ultrasonography, Doppler, Color: Ultrasonography applying the Doppler effect, with the superposition of flow information as colors on a gray scale in a real-time image. This type of ultrasonography is well-suited to identifying the location of high-velocity flow (such as in a stenosis) or of mapping the extent of flow in a certain region.Liver Function Tests: Blood tests that are used to evaluate how well a patient's liver is working and also to help diagnose liver conditions.Fatty Liver: Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Azygos Vein: A vein which arises from the right ascending lumbar vein or the vena cava, enters the thorax through the aortic orifice in the diaphragm, and terminates in the superior vena cava.Retinal Vein: Central retinal vein and its tributaries. It runs a short course within the optic nerve and then leaves and empties into the superior ophthalmic vein or cavernous sinus.Liver Regeneration: Repair or renewal of hepatic tissue.Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.Dogs: The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)Perfusion: Treatment process involving the injection of fluid into an organ or tissue.Portasystemic Shunt, Transjugular Intrahepatic: A type of surgical portasystemic shunt to reduce portal hypertension with associated complications of esophageal varices and ascites. It is performed percutaneously through the jugular vein and involves the creation of an intrahepatic shunt between the hepatic vein and portal vein. The channel is maintained by a metallic stent. The procedure can be performed in patients who have failed sclerotherapy and is an additional option to the surgical techniques of portocaval, mesocaval, and splenorenal shunts. It takes one to three hours to perform. (JAMA 1995;273(23):1824-30)Retinal Vein Occlusion: Blockage of the RETINAL VEIN. Those at high risk for this condition include patients with HYPERTENSION; DIABETES MELLITUS; ATHEROSCLEROSIS; and other CARDIOVASCULAR DISEASES.Transplants: Organs, tissues, or cells taken from the body for grafting into another area of the same body or into another individual.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Gluconeogenesis: Biosynthesis of GLUCOSE from nonhexose or non-carbohydrate precursors, such as LACTATE; PYRUVATE; ALANINE; and GLYCEROL.Corrosion Casting: A tissue preparation technique that involves the injecting of plastic (acrylates) into blood vessels or other hollow viscera and treating the tissue with a caustic substance. This results in a negative copy or a solid replica of the enclosed space of the tissue that is ready for viewing under a scanning electron microscope.Phlebitis: Inflammation of a vein, often a vein in the leg. Phlebitis associated with a blood clot is called (THROMBOPHLEBITIS).Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.Portacaval Shunt, Surgical: Surgical portasystemic shunt between the portal vein and inferior vena cava.Purkinje Cells: The output neurons of the cerebellar cortex.Radiology, Interventional: Subspecialty of radiology that combines organ system radiography, catheter techniques and sectional imaging.Drug-Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, and chemicals from the environment.End Stage Liver Disease: Final stage of a liver disease when the liver failure is irreversible and LIVER TRANSPLANTATION is needed.Vascular Malformations: A spectrum of congenital, inherited, or acquired abnormalities in BLOOD VESSELS that can adversely affect the normal blood flow in ARTERIES or VEINS. Most are congenital defects such as abnormal communications between blood vessels (fistula), shunting of arterial blood directly into veins bypassing the CAPILLARIES (arteriovenous malformations), formation of large dilated blood blood-filled vessels (cavernous angioma), and swollen capillaries (capillary telangiectases). In rare cases, vascular malformations can result from trauma or diseases.Regional Blood Flow: The flow of BLOOD through or around an organ or region of the body.Liver Failure: Severe inability of the LIVER to perform its normal metabolic functions, as evidenced by severe JAUNDICE and abnormal serum levels of AMMONIA; BILIRUBIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASES; and albumin/globulin ratio. (Blakiston's Gould Medical Dictionary, 4th ed)Butter: The fatty portion of milk, separated as a soft yellowish solid when milk or cream is churned. It is processed for cooking and table use. (Random House Unabridged Dictionary, 2d ed)Rats, Sprague-Dawley: A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.Glucose: A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.Blood Flow Velocity: A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.Liver Cirrhosis, Experimental: Experimentally induced chronic injuries to the parenchymal cells in the liver to achieve a model for LIVER CIRRHOSIS.Rats, Inbred Strains: Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding.Functional Laterality: Behavioral manifestations of cerebral dominance in which there is preferential use and superior functioning of either the left or the right side, as in the preferred use of the right hand or right foot.Kupffer Cells: Specialized phagocytic cells of the MONONUCLEAR PHAGOCYTE SYSTEM found on the luminal surface of the hepatic sinusoids. They filter bacteria and small foreign proteins out of the blood, and dispose of worn out red blood cells.Portasystemic Shunt, Surgical: Surgical venous shunt between the portal and systemic circulation to effect decompression of the portal circulation. It is performed primarily in the treatment of bleeding esophageal varices resulting from portal hypertension. Types of shunt include portacaval, splenorenal, mesocaval, splenocaval, left gastric-caval (coronary-caval), portarenal, umbilicorenal, and umbilicocaval.Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.Image Processing, Computer-Assisted: A technique of inputting two-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer.Angiography: Radiography of blood vessels after injection of a contrast medium.Rats, Wistar: A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.Ultrasonography, Doppler, Pulsed: Ultrasonography applying the Doppler effect, with velocity detection combined with range discrimination. Short bursts of ultrasound are transmitted at regular intervals and the echoes are demodulated as they return.Venous Thrombosis: The formation or presence of a blood clot (THROMBUS) within a vein.Hepatic Duct, Common: Predominantly extrahepatic bile duct which is formed by the junction of the right and left hepatic ducts, which are predominantly intrahepatic, and, in turn, joins the cystic duct to form the common bile duct.Viscera: Any of the large interior organs in any one of the three great cavities of the body, especially in the abdomen.Liver Cirrhosis, Alcoholic: FIBROSIS of the hepatic parenchyma due to chronic excess ALCOHOL DRINKING.Perianal GlandsPortography: Examination of the portal circulation by the use of X-ray films after injection of radiopaque material.Heterotaxy Syndrome: Abnormal thoracoabdominal VISCERA arrangement (visceral heterotaxy) or malformation that involves additional CONGENITAL HEART DEFECTS (e.g., heart isomerism; DEXTROCARDIA) and/or abnormal SPLEEN (e.g., asplenia and polysplenia). Irregularities with the central nervous system, the skeleton and urinary tract are often associated with the syndrome.Ascites: Accumulation or retention of free fluid within the peritoneal cavity.Alanine Transaminase: An enzyme that catalyzes the conversion of L-alanine and 2-oxoglutarate to pyruvate and L-glutamate. (From Enzyme Nomenclature, 1992) EC 2.6.1.2.Neural Pathways: Neural tracts connecting one part of the nervous system with another.Graft Occlusion, Vascular: Obstruction of flow in biological or prosthetic vascular grafts.RNA, Messenger: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.Mice, Inbred C57BLMicrosomes, Liver: Closed vesicles of fragmented endoplasmic reticulum created when liver cells or tissue are disrupted by homogenization. They may be smooth or rough.Insulin: A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).Constriction: The act of constricting.Glucagon: A 29-amino acid pancreatic peptide derived from proglucagon which is also the precursor of intestinal GLUCAGON-LIKE PEPTIDES. Glucagon is secreted by PANCREATIC ALPHA CELLS and plays an important role in regulation of BLOOD GLUCOSE concentration, ketone metabolism, and several other biochemical and physiological processes. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1511)Brain: The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.Portal Pressure: The venous pressure measured in the PORTAL VEIN.Ligation: Application of a ligature to tie a vessel or strangulate a part.Aspartate Aminotransferases: Enzymes of the transferase class that catalyze the conversion of L-aspartate and 2-ketoglutarate to oxaloacetate and L-glutamate. EC 2.6.1.1.Vascular Neoplasms: Neoplasms located in the vasculature system, such as ARTERIES and VEINS. They are differentiated from neoplasms of vascular tissue (NEOPLASMS, VASCULAR TISSUE), such as ANGIOFIBROMA or HEMANGIOMA.Hemostatics: Agents acting to arrest the flow of blood. Absorbable hemostatics arrest bleeding either by the formation of an artificial clot or by providing a mechanical matrix that facilitates clotting when applied directly to the bleeding surface. These agents function more at the capillary level and are not effective at stemming arterial or venous bleeding under any significant intravascular pressure.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Cadaver: A dead body, usually a human body.Venous Insufficiency: Impaired venous blood flow or venous return (venous stasis), usually caused by inadequate venous valves. Venous insufficiency often occurs in the legs, and is associated with EDEMA and sometimes with VENOUS STASIS ULCERS at the ankle.Carbon Tetrachloride: A solvent for oils, fats, lacquers, varnishes, rubber waxes, and resins, and a starting material in the manufacturing of organic compounds. Poisoning by inhalation, ingestion or skin absorption is possible and may be fatal. (Merck Index, 11th ed)Multidetector Computed Tomography: Types of spiral computed tomography technology in which multiple slices of data are acquired simultaneously improving the resolution over single slice acquisition technology.Blood Glucose: Glucose in blood.Tomography, Spiral Computed: Computed tomography where there is continuous X-ray exposure to the patient while being transported in a spiral or helical pattern through the beam of irradiation. This provides improved three-dimensional contrast and spatial resolution compared to conventional computed tomography, where data is obtained and computed from individual sequential exposures.Imaging, Three-Dimensional: The process of generating three-dimensional images by electronic, photographic, or other methods. For example, three-dimensional images can be generated by assembling multiple tomographic images with the aid of a computer, while photographic 3-D images (HOLOGRAPHY) can be made by exposing film to the interference pattern created when two laser light sources shine on an object.Organ Size: The measurement of an organ in volume, mass, or heaviness.

*Central veins of liver

The central veins of liver (or central venules) are veins found at the center of hepatic lobules (one vein at each lobule ... Anatomy photo: digestive/mammal/liver3/liver2 - Comparative Organology at University of California, Davis "central veins of ... They receive the blood mixed in the liver sinusoids and return it to circulation via the hepatic veins. ...

*Hepatic veins

... and ultimately from numerous central veins of the liver lobules. None of the hepatic veins have valves. The hepatic veins are ... These are larger than the group of lower hepatic veins that can number from six to twenty. All of the hepatic veins drain into ... They are one of two sets of veins connected to the liver, the others are the portal veins. The large hepatic veins arise from ... ISBN 978-1-4160-6257-8. Hepatic veins - definition - medterms.com Hepatic veins - Ultrasound - University of the Health ...

*Congestive hepatopathy

... the blood being dammed back in the inferior vena cava and hepatic veins. Central regions of the hepatic lobules are red-brown ... the dark spots represent the dilated and congested hepatic venules and small hepatic veins. The paler areas are unaffected ... Increased pressure in the sublobular branches of the hepatic veins causes an engorgement of venous blood, and is most ... When severe and longstanding, hepatic congestion can lead to fibrosis; if congestion is due to right heart failure, it is ...

*Liver

The central veins coalesce into hepatic veins, which leave the liver and drain into the inferior vena cava. The biliary tract ... Lobules are the functional units of the liver. Each lobule is made up of millions of hepatic cells (hepatocytes) which are the ... The lobules are roughly hexagonal, and consist of plates of hepatocytes radiating from a central vein.[page needed]The central ... The liver receives a dual blood supply from the hepatic portal vein and hepatic arteries. The hepatic portal vein delivers ...

*Lobules of liver

... each of which is centered on the line connecting two portal triads and extends outwards to the two adjacent central veins. The ... "hepatic lobule", without qualification, typically refers to the classical lobule. From a metabolic perspective, the functional ... A hepatic lobule is a small division of the liver defined at the histological scale. It should not be confused with the ... The hepatic lobule is a building block of the liver parenchyma consisting of a portal triad, hepatocytes arranged in linear ...

*Liver cytology

... channels that receive blood from terminal branches of the hepatic artery and portal vein and make it flow to the central veins ... The hepatocytes are the parenchymal cells of the liver, which form the lobules. They are intimately associated with the ... These hepatic stellate cells, also named lipocytes, have lipid drops in their cytosol. It is thought that these drops store a ... Hepatic stellate cells rest over the Remak trabecules, and they emit extensions to the sinusoids. Julio, Sepúlveda Saavedra ( ...

*Hepatotoxicity

... (from hepatic toxicity) implies chemical-driven liver damage. Drug-induced liver injury is a cause of acute and ... The liver plays a central role in transforming and clearing chemicals and is susceptible to the toxicity from these agents. ... 75% of blood coming to the liver arrives directly from gastrointestinal organs and then spleen via portal veins that bring ... common type of drug-induced liver cell necrosis where the injury is largely confined to a particular zone of the liver lobule. ...

*Pancreas

It begins on the right in the omental tuber, and is in relation with the celiac artery, from which the hepatic artery courses ... The body and neck of the pancreas drain into the splenic vein; the head drains into the superior mesenteric and portal veins. ... Pancreatitis is likely to cause intense pain in the central abdomen, that often radiates to the back, and may be associated ... The intercalated ducts drain into larger ducts within the lobule, and finally interlobular ducts. The ducts are lined by a ...

*Index of anatomy articles

... hemidiaphragm hemiparesis hemisphere hemothorax hepatic hepatic artery hepatic flexure hepatic portal vein hepatic veins ... central canal Central gelatinous substance of spinal cord central nucleus of inferior colliculus central retinal artery central ... vein lingula lip lipofuscin Lissauer's tract lissencephalic list of human anatomical features Little's area liver lobule locus ... sulcus central tegmental tract centromedian nucleus centrum semi centrum semiovale cephalic cephalic vein cerebellar peduncle ...

*Lymphatic system

... drained into the hepatic portal veins, and thus into the liver. The findings of Ruphus and Herophilos were further propagated ... The central nervous system also has lymphatic vessels, as discovered by University of Virginia Researchers. The search for T- ... In most species, the thymus consists of lobules divided by septa which are made up of epithelium and is therefore an epithelial ... The arteries and veins supplying the lymph node with blood enter and exit through the hilum. The region of the lymph node ...

*Lung

The respiratory tract ends in lobules. Each lobule consists of a respiratory bronchiole, which branches into alveolar ducts and ... The central chemoreceptor is particularly sensitive to the pH of the cerebrospinal fluid, which is directly influenced by the ... Crocodilians also rely on the hepatic piston method, in which the liver is pulled back by a muscle anchored to the pubic bone ( ... The lungs filter out small blood clots from veins and prevent them from entering arteries and causing strokes. The lungs also ...
Looking for online definition of hepatic vein thrombosis syndrome in the Medical Dictionary? hepatic vein thrombosis syndrome explanation free. What is hepatic vein thrombosis syndrome? Meaning of hepatic vein thrombosis syndrome medical term. What does hepatic vein thrombosis syndrome mean?
Hepatic venous outflow block caused by short-length hepatic vein stenoses. - D Valla, A Hadengue, M el Younsi, N Azar, G Zeitoun, M J Boudet, G Molas, J Belghiti, S Erlinger, J M Hay, J P Benhamou
Background and Aim Hepatic resection involves not only complete removal of tumors but also preservation of optimal liver function after surgery. This study introduces the technique of inferior right...
The liver is divided into eight segments based on the branching of the portal triads and hepatic veins. The structures of the portal triad (hepatic artery, portal vein, and biliary duct) are separate extrahepatically but enter the hepatic hilus ensheathed within a thickened layer of the Glisson capsule. The three main hepatic veins divide the liver into four sectors, each of which is supplied by a portal pedicle. The caudate lobe is an exception because its venous drainage is directly into the vena cava and therefore independent of the major hepatic veins. The four sectors delimited by the hepatic veins are called the portal sectors, and ...
Looking for hepatic vein? Find out information about hepatic vein. A blood vessel that drains blood from the liver into the inferior vena cava Explanation of hepatic vein
Alterations in protein synthesis in primary cultured rat liver parenchymal cells were examined after their exposure to the potent carcinogens, polychlorinated biphenyl (PCB) congeners. Co-planar PCB congeners (3,4,5,3′,4′-PCB and 3,4,5,3′,4′,5′-PCB) (10 nM) induced a protein, the Mr of which was 25,000 (25 k protein) under denaturing conditions. However, non-co-planar PCB congeners and several xenobiotics, which induce microsomal proteins, did not induce the 25 k protein. By using immunoblotting, the 25 k protein was identified as glutathione S-transferase P-form (GST-P, 7-7, EC 2.5.1.18).. ...
Hepatic vein thrombosis (HVT) is an obstruction in the veins of the liver caused by a blood clot. This condition blocks blood flow from the liver to the heart.
TY - JOUR. T1 - Biliary complications in adult living donor liver transplantation with duct-to-duct hepaticocholedochostomy or Roux-en-Y hepaticojejunostomy biliary reconstruction. AU - Kawachi, Shigeyuki. AU - Shimazu, Motohide. AU - Wakabayashi, Go. AU - Hoshino, Ken. AU - Tanabe, Minoru. AU - Yoshida, Masashi. AU - Morikawa, Yasuhide. AU - Kitajima, Masaki. PY - 2002. Y1 - 2002. N2 - Background. The aim of this study was to compare lhe incidence of biliary complications after adult living donor liver transplantation (ALDLT) with Roux-en-Y hepaticojejunostomy (R-Y HJ) or duct-to-duct hepaticocholedochostomy (D-D HC). Methods. Biliary complications were reviewed in 20 consecutive ALDLT recipients surviving more than 1 month, including 10 patients who underwent R-Y HJ and 10 patients who underwent D-D HC reconstructions. Results. Ten biliary complications were seen in 8 ...
Rat liver parenchymal cells express Na+-dependent and Na+-independent nucleoside transport activity. The Na+-dependent component shows kinetic properties and substrate specificity similar to those reported for plasma membrane vesicles [Ruiz-Montasell, Casado, Felipe and Pastor-Anglada (1992) J. Membr. Biol. 128, 227-233]. This transport activity shows apparent Km values for uridine in the range 8-13 μM and a Vmax of 246 pmol of uridine per 3 min per 106 cells. Most nucleosides, including the analogue formycin B, cis-inhibit Na+-dependent uridine transport, although thymidine and cytidine are poor inhibitors. Inosine and adenosine inhibit Na+-dependent uridine uptake in a dose-dependent manner, reaching total inhibition. Guanosine also inhibits Na+-dependent uridine uptake, although there is some residual transport activity (35% of the control values) that is resistant to high concentrations of guanosine but may be inhibited by low concentrations of adenosine. The transport activity that is ...
http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1527-6465&volume=8&spage=C65&epage=&date=2002&atitle=Including+the+middle+hepatic+vein+in+a+right+lobe+liver+graft+-+analysis+of+safety+in+90+living+donors+(Abstract ...
ALVES, Rogério Camargo Pinheiro et al. Predictive factors of early graft loss in living donor liver transplantation. Arq. Gastroenterol. [online]. 2012, vol.49, n.2, pp.157-161. ISSN 0004-2803. http://dx.doi.org/10.1590/S0004-28032012000200011.. CONTEXT: Living donor liver transplantation has become an alternative to reduce the lack of organ donation. OBJECTIVE: To identify factors predictive of early graft loss in the first 3 months after living donor liver transplantation. METHODS: Seventy-eight adults submitted to living donor liver transplantation were divided into group I with 62 (79.5%) patients with graft survival longer than 3 months, and group II with 16 (20.5%) patients who died and/or showed graft failure within 3 months after liver transplantation. The variables analyzed were gender, age, etiology of liver disease, Child-Pugh classification, model of end-stage liver disease (MELD score), pretransplantation serum sodium level, and graft weight-to-recipient body weight (GRBW) ratio. ...
Dr Massimo Pinzani and colleagues from Italy evaluated the ability of liver stiffness measurement vs hepatic venous pressure gradient to to predict severe portal hypertension.. The research team assessed 61 consecutive patients with Hepatitis C virus-related chronic liver disease.. The researchers found a strong relationship between liver stiffness measurement and hepatic venous pressure gradient measurements in the overall population.. The correlation was excellent for hepatic venous pressure gradient values less than 10 or 12 mm Hg.. However, the team noted that linear regression analysis was not optimal for hepatic venous pressure gradient values 10 mm Hg or 12 mm Hg.. The area under the receiver of operator curve for the prediction of hepatic venous pressure gradient for 10 and 12 mm Hg were 0.99 and 0.92, respectively.. The team noted ...
The Budd-Chiari syndrome, or Chiaris syndrome, is the disease complex which follows hepatic vein occlusion. It is a moderately well popularized secondary abdominal response to several disease processes, but the number of reported cases remains remarkably small. During the past 32 months seven autopsy-proved cases and four presumptive cases have been observed. This appears to be a large experience with the syndrome, perhaps explained by the fact that a large tumor center was the source of material. From 1910 to 1939 at the Mayo Clinic 20 instances were encountered.1 Only five were found during 11,979 autopsies at Stanford University.2. Lambron ...
Objectives: Portal vein (PV) reconstruction is a crucial factor for successful living donor liver transplantation (LDLT). Portal vein thrombosis (PVT) remains a critical problem in LDLT because of technical demands and sufficient venous graft harvesting. This study aimed to describe in detail of PV reconstruction and outcomes of patients with PVT.. Methods: We performed adult-to-adult LDLT for 123 patients between March 2002 and December 2016. Thirteen patients (10.6%) had PVT at the time of LDLT, which were classified as grade I in 2 patients, grade II in 4 patients, grade III in 6 patients and grade IV in 1 patient, according to Yerdel's classification. We retrospectively analyzed the surgical technique and postoperative complications of PV reconstruction for patients with PVT, and compared to patients without PVT.. Results: Surgical treatments for 13 patients with PVT were as follows: thrombectomy alone in 2 patients, replaced interpositional venous grafts in 8 patients: 3 using internal ...
The evaluation of the hepatic parenchyma in patients with chronic liver disease is important to assess the extension, localization and relationship with adjacent anatomical structures of possible lesions. This is usually performed with conventional abdominal ultrasound, CT-scan or magnetic resonance imaging. In this context, the feasibility and the safety of intravascular ultrasound in the liver have not been assessed yet. We tested the safety and performance of an intracardiac echography (ICE) catheter applied by a transjugular approach into the hepatic veins in patients with chronic liver disease undergoing hepatic hemodynamic measurements. Five patients were enrolled in this pilot study. The insertion of the ICE catheter was possible into the right and middle, but not into the left hepatic vein. The position of the ICE was followed using ...
TY - JOUR. T1 - Liver regeneration in donors and adult recipients after living donor liver transplantation. AU - Haga, Junko. AU - Shimazu, Motohide. AU - Wakabayashi, Go. AU - Tanabe, Minoru. AU - Kawachi, Shigeyuki. AU - Fuchimoto, Yasushi. AU - Hoshino, Ken. AU - Morikawa, Yasuhide. AU - Kitajima, Masaki. AU - Kitagawa, Yuko. PY - 2008/12/1. Y1 - 2008/12/1. N2 - In living donor liver transplantation, the safety of the donor operation is the highest priority. The introduction of the right lobe graft was late because of concerns about donor safety. We investigated donor liver regeneration by the types of resected segments as well as recipients to assess that appropriate regeneration was occurring. Eighty-seven donors were classified into 3 groups: left lateral section donors, left lobe donors, and right lobe donors. Forty-seven adult recipients were classified as either left or right lobe grafted recipients. Volumetry was retrospectively performed at 1 week, 1, 2, 3, and 6 months, and 1 year ...
During this procedure, the blood flow from Abbys liver will be directed to her lungs. Currently the blood flows from her liver through her hepatic veins into her heart where it mixes with oxygen rich blood that has just come from her lungs and is then pumped through her body. This presents two problems: first, since this blood from her liver is very low in oxygen when it reaches her heart, it lowers her overall oxygen saturation when it mixes with the oxygen rich blood in her heart. Second, since her lungs are not receiving direct blood flow from her liver, they lack the unknown protein or enzyme that keeps them for forming collateral veins. So, as I write this Dr. Birch is doing his very best to correct this issue. Typically, the Fontan is performed by detaching the hepatic veins from the heart and patching the whole. Then theses ...
The aim of present study was to evaluate relationships between degree of portal hypertension, severity of the disease, and bleeding status in patients with liver cirrhosis. Patients and methods. All study patients with liver cirrhosis underwent hepatic venous pressure gradient measurements, endoscopy, clinical and biochemical evaluation. Liver function was evaluated according to Child-Turcotte-Pugh (Childs) scoring system. Patients with decompensated cirrhosis (presence of severe ascites, acute variceal bleeding occurring within 14 days, hepatorenal syndrome, cardiopulmonary disorders, transaminase levels >10 times higher the upper normal limit), active alcohol intake, use of antiviral therapy and/or beta-blockers were excluded from the study. Results. One hundred twenty-eight patients with liver cirrhosis (male/female, 67/61; mean age, 53.8±12.7 years) were included into the study. Etiology of cirrhosis was viral hepatitis, alcoholic liver disease, cryptogenic and ...
Various studies have been designed for evaluating the severity of liver abnormalities by Doppler ultrasound in patients with chronic liver disease [10-12]. The pattern of blood flow in the HV is one of the parameters to be evaluated. Three grades of hepatic waveforms have been described by Bolondi et al. [13] to indicate changes from the normal triphasic pattern to the flat pattern widely used in older studies of chronic liver disease [13-15]. Nowadays, more studies are carried out to determine if analyses of HV waveforms may be useful in the assessment of PHT [9, 16]. In the present study, we suggest that an abnormal HV Doppler curve and quantitative index DI may be non-specific indicators of liver abnormality as well as of PP in PHT patients. Furthermore, by comparing the hemodynamic changes in the portal vein and hepatic artery and histological changes in liver parenchyma, we attempted to discuss the mechanism of abnormal HV waveform.. ...
Expression of ECM proteins fibulin-1 and -2 in acute and chronic liver disease and in cultured rat liver cells. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
接著,看圖可以發現,liver被3條 hepatic vein分成4份,而其再根據portal vein 分支我們把它分成8塊。. 最要記得且特別的是S1 是尾狀葉 caudate lobe,是在S4 後方。從尾狀葉起始,照順時針方式填入順序(腦海中請記得圖),想像它是兩個時鐘 (感謝王瑞芳學姊的idea),如下:. ...
Evidence-based recommendations on chemosaturation via percutaneous hepatic artery perfusion and hepatic vein isolation for primary or metastatic liver cancer
The treatment of BCS is best done by a team involving a pediatric gastroenterologist, interventional radiologist, pediatrician and a liver surgeon. The treatment can be divided into supportive and definitive management:. Supportive care: The nutrition of the patient is improved. Large ascites can cause difficulty in breathing. This condition requires removal of fluid from the abdomen by inserting a needle (paracentesis) only if there is difficulty in breathing or for the sake of testing the fluid. In order to decrease the hypercoagulable state, patients are usually started on oral anticoagulants. The common drug used is Warfarin.. Definitive management:. Radiological intervention: During hepatic venogram (study of venous blood flow of liver), the anatomy and pressure in the hepatic veins and their caliber is noted. Depending upon the diameter of the hepatic ...
BOTHA, J et al. Living donor liver transplantation in South Africa: the donor experience. S. Afr. j. surg. [online]. 2019, vol.57, n.3, pp.11-16. ISSN 2078-5151. http://dx.doi.org/10.17159/2078-5151/2019/v57n3a2998.. BACKGROUND: Living donor liver transplantation (LDLT) plays a crucial role in liver transplant programmes, particularly in regions with a scarcity of deceased donor organs and especially for paediatric recipients. LDLT is a complex and demanding procedure which places a healthy living donor in harms way. Donor safety is therefore the overriding concern. This study aimed to report our standardised approach to the evaluation, technical aspects and outcomes of LDLT donor hepatectomy at Wits Donald Gordon Medical CentreMETHODS: The study population consisted of all patients undergoing LDLT donor hepatectomy since the inception of the programme in March 2013 until 2018. Sixty five living donor hepatectomies were performed. Primary outcome measures included donor demographics, operative ...
A liver sinusoid is a type of sinusoidal blood vessel (with fenestrated, discontinuous endothelium) that serves as a location for mixing of the oxygen-rich blood from the hepatic artery and the nutrient-rich blood from the portal vein. Hepatocytes are separated from the sinusoids by the space of Disse. Kupffer cells are located inside the sinusoids and can take up and destroy foreign material such as bacteria. Hepatic stellate cells are present in the space of Disse and are involved in scar formation in response to liver damage. The sinusoidal endothelial cells are cultured for a variety of research purposes. The utility of these cells are of particular interest. One problem to overcome is the reversing of cellular differentiation that has made these cells highly specialized phenotypically in vitro. Human liver sinusoid A single lobule of the liver of a pig. X 60. SIU SOM Histology GI Sellaro TL, Ravindra AK, Stolz DB, Badylak SF. (September ...
ABSTRACT- To clarify the relation of pericentral fibrosis to portal hypertension, measurements of portal vascular resistance in vitro and blood pressures of several key points in hepatic vascular pathways in vivo were undertaken in rats given dimethylnitrosamine. Administration of dimethylnitrosamine induced tortuosity and narrowing of the peripheral branches of the hepatic vein due to pericentral fibrosis. No significant change was produced in the sinusoids and the portal vein branches. The portal vascular resistance was increased and the portal vein pressure was elevated markedly. The blood pressure gradient was steep in the intrahepatic vein, but not in the intrahepatic portal vein or the sinusoids, as compared to control. These data suggest that deformation of the peripheral branches of the hepatic vein ...
Clinically, the Valsalva maneuver is considered as main cause of defecation syncope and surgery Hepatic hemodynamics during Valsalva maneuver performed in a patient with functional suprahepatic inferior vana cava (IVC) obstruction during the Valsalva maneuver [12]. Collapsed IVC showed during the maneuver in normal healthy subjects using ultrasonography study, but IVC howed angular appearance and not collapsed during the maneuver in the venography study [10,11]. The change of IVC during the maneuver is ambiguous and hemodynamic contribution of hepatic vein and portal vein during the maneuver has not been studied in normal healthy subjects. Duplex Doppler ultrasonography of the liver provides important information about liver condition [11,13]. Hepatic vein flow depends on hepatic parenchymal compliance, thoracoabdominal pressure, and right ...
A B ST R A CT The effect of equal (1.1±0.1 g/kg body wt) amounts of glucose administered orally, or by peripheral intravenous or intraportal infusion on hepatic glucose uptake and fractional hepatic extraction of insulin and glucagon was studied in conscious dogs with chronically implanted Doppler flow probes on the portal vein and hepatic artery and catheters in the portal vein, hepatic vein, carotid artery, and superior mesenteric vein. Portal vein and hepatic vein plasma flow increased only after oral glucose administration. Arterial plasma glucose increased equally to 150-160 mg/100 ml after all three routes of glucose administration. Portal vein glucose was similar after oral (195±15 mg/100 ml) and intraportal glucose infusion (215±11 mg/100 ml) and significantly higher than after peripheral intravenous glucose. ...
PURPOSE: LRLT in children is a method to provide organs for transplantation. We report 2 cases of LLLS for pediatric LRLT. METHOD: Donor position: lithotomy with surgeon in French position. Trocars: three 12 mm, placed 2 cm upper the supra-umbilical mid-line and sub-costal bi-lateral on the nipple lines; one 5 mm in epigastrium. Special instrumentation: harmonic scissor, ligasure®, Hem-O-Lock clips, and Endo Catch-II® bag. Main steps: division of round, falciform, left triangular ligaments and of lesser omentum; inspection of anatomy; hepatic hilum dissection with exposure of the left hepatic artery; dissection of the right side of the falciform ligament with exposure of the left branch of the portal vein; dissection of the Arantius ligament and exposure of the left hepatic vein; parenchymal dissection with hilar plate and left biliary duct(s) section; Pfannestiel incision; placement of the graft (S2-3) into ...
When patients develop acute liver failure, severe complications arise rapidly after the first signs of liver disease, and patients health can deteriorate rapidly.
There is only 1 umbilical vein, and it remains open and viable for cannulation for up to 1 week after birth. The umbilical vein carries oxygenated blood from the placenta to the fetus. The UVC passes into the umbilical vein through the umbilicus and follows this path: junction of the right and left portal vein in the liver, the ductus venosus, crosses at the level of the right and left hepatic vein, and enters the inferior vena cava up to the junction of the inferior vena cava and right atrium. ...
Health, ...Living donor liver transplantation (LDLT) has been used to alleviate t...A research article to be published on August 28 2009 in the World ...The results demonstrated that the Chengdu formula was reliable by its ...With national multicenter data in the future the Chengdu formula for ...,,Evaluation,of,standard,liver,volume,formula,for,Chinese,adults,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
Living donor liver transplants - Department of Surgery - Living Donor Liver Transplant. We provides LiverActive Liver Detox formula contains several natural ingredients to help maintain a healthy liver. Listen to your liver and dont ignore the warning signs.
Inferior Vena Cava learn with complete stomach Liver LONGITUDINAL photos 1. Longitudinal picture of the left lobe of the liver to incorporate the inferior margin and the aorta. Left lobe Anterior enhanced Bowel Pancreas physique Inferior Aorta backbone Diaphragm Posterior L A B E L E D : LIVER TRV LT LOBE eighty three Splenic vein Splenic artery 2. Longitudinal photo of the left lobe of the liver to incorporate the diaphragm and caudate lobe. Anterior Hepatic vein enhanced Left lobe Ligamentum venosum Inferior Inferior vena cava Splenic vein Diaphragm Caudate lobe Posterior L A B E L E D : LIVER SAG LT LOBE eighty four 3. Longitudinal photograph of the perfect lobe of the liver to incorporate the inferior vena cava the place it passes throughout the liver. correct lobe Hepatic Hepatic vein vein Anterior Portal vein belly Inferior more advantageous Bowel IVC Diaphragm correct lobe Caudate lobe correct renal ...
1. In the liver of portal cirrhosis there is a far freer communication between the arterial and portal currents than in the normal liver.. 2. Factors contributing to the increased portal pressure in portal cirrhosis are (1) the direct communication of the arterial pressure to the portal vessels through dilated capillaries, (2) the larger volume-flow of the hepatic artery in proportion to the portal flow in cirrhosis as compared to that in the normal liver.. 3. A portal cirrhotic liver gives passage to an amount of portal fluid proportionate to .its weight. There is no obstruction to the portal vessels from fibrosis in the large portal cirrhotic liver.. 4. From an arterial inflow there is a free return flow through the portal as well as through the hepatic veins in both normal and cirrhotic livers.. 5. From a portal inflow the return is through the hepatic vein only. The Gads ...
The stress of orthotopic living donor liver transplantation in patients with cirrhosis could induce worsening of an already recorded myocardial dysfunction or may be associated with a new myocardial dysfunction in patients previously having normal myocardial functions, therefore this study will be designed for intra-operative detection of new onset ventricular dysfunction or worsening of already diagnosed ventricular dysfunction in living donor liver transplant recipient and the possible contribution of several hemodynamic and oxygenation parameters in the generation of any cardiovascular function impairment will be also investigated and to determine the impact of ventricular dysfunction on early (7 PO days) graft function, 28 days survival and patient outcomes ...
Living donor liver transplantation offers an alternative when time matters. Cleveland Clinics Living liver donor program is the only one in Ohio performing both adult and pediatric living-donor liver transplants.
Noida, 11 March 2015: In a rare case of clinical excellence, Fortis Hospital, Noida, saved the life of a 47 year old patient, George Ikuje Obe, from Nigeria, suffering from the Budd-Chiari Syndrome (BCS) since the last 12 years. The surgery was led by Dr. Vivek Vij, Director, Liver Transplant at Fortis Hospital Noida along with a team of eight surgeons and 14 doctors including anesthetist and cardiac thoracic surgeon. The 14 hour long surgery comprised of joining the liver with the heart through a passage created from the vein of the liver along with conducting the liver transplant. This is the first such surgery in India and only three to four such surgeries have been conducted in the world. The patient is doing well and will remain on anti-coagulation drug for life to prevent any blockages in the future.. Budd-Chiari syndrome is a condition caused by blockage of the hepatic veins that drains the liver. It presents with the classical set of ...
A 63-year-old woman was admitted to our cancer center in 2015, complaining of right upper abdominal pain. Otherwise she was healthy with good general condition. From radiologic evaluations in other hospital, she was diagnosed with primary HCC associated with hepatitis B virus and liver cirrhosis. Additional computed tomography (CT) and magnetic resonance (MR) imaging for staging workup showed that over 16 cm mass at the right hepatic lobe with tumor thrombus in the right portal and main portal vein (Fig. 1). Right hepatic vein and suprahepatic inferior vena cava were also involved. Multiple portocaval and para-aortic lymph nodes were enlarged. At the time of initial visit, her alpha fetoprotein (AFP) level was ,4,340 ng/mL (normal range [NR], 0.1 to 9.0 ng/mL), and the results of liver function tests are aspartate transaminase (AST) 298 IU/L (NR, 0 to 35 IU/L), alanine transaminase (ALT) 31 IU/L (NR, 0 to 35 ...
In living donor liver transplantation, the recipient liver undergoes more rapid regeneration than the remnant liver in the donor. In this study we investigated the factors which may be responsible for the difference in the regenerative response between the donor and the recipient. <br>Long Evans rats were subjected to either partial hepatectomy (PH) or sham operation (SH) and were treated with liver cytosol (C) and cyclosporine (Cy). The rats were sacrificed at 24, 48, 72 and 96 hours and 1 and 2 weeks postoperatively. The livers were removed to determine the liver weight/body weight (LW / BW ) ratio and the mitotic index. <br>The mitotic index, serum aspartate transferase (AST) and serum alanine transferase (ALT), although unchanged in the SH groups, were increased in the rats treated with PH + C + Cy, and were greater than after PH only. However LW / BW ratios increased after PH but had returned to preoperative levels by 2 weeks. The changes in LW / BW ratio were not modified by the
Hwang, S., Lee, S.-G., Moon, D.-B., Ahn, C.-S., Kim, K.-H., Lee, Y.-J., Ha, T.-Y. and Song, G.-W. (2007), Salvage living donor liver transplantation after prior liver resection for hepatocellular carcinoma. Liver Transpl, 13: 741-746. doi: 10.1002/lt.21157 ...
Therefore, an alternative, non-invasive technique allowing clinicians to diagnose and grade PH in patients with cirrhosis and that could replace HVPG is needed. Transient elastography (TE) has been established as a non-invasive method of measuring liver stiffness due to its diagnostic accuracy in hepatic fibrosis [7]. Accumulating evidence suggests that TE adequately reflects the findings of HVPG, indicating that it is a useful modality for evaluating PH and cirrhotic complications [8-14]. However, some studies have reported conflicting results indicating TE is not sufficiently accurate to replace HVPG due to its insufficient sensitivity or specificity [15]. Hence, controversy remains regarding the usefulness of TE for assessing PH. Systematic reviews (SRs) and meta-analyses (MAs) have facilitated objective evaluation of existing evidence [16-20]. Shi et al. [21] reported the results of their MA for TE in the diagnosis of PH and esophageal varices and further studies should ...
Nearly three out of four Japanese patients who underwent living donor liver transplantation following acute liver failure managed to live for more than ten years after the surgery.
The Department of Surgery of the University of Hong Kong will host "Adult Right Living Donor Liver Transplantation - 20 Years On" on Thursday, Aug. 18, at the Renaissance Hong Kong Harbour View Hotel in Wan Chai ...
When Budd-Chiari syndrome is suspected, measurements are made of liver enzyme levels and other organ markers (creatinine, urea, electrolytes, LDH). Budd-Chiari syndrome is diagnosed using ultrasound studies of the abdomen, although occasionally more invasive methods have to be used (retrograde angiography). Liver biopsy is sometimes necessary to differentiate between Budd-Chiari syndrome and other causes of hepatomegaly and ascites, such as galactosemia or Reyes syndrome. ...
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Even if you opt for a living donor liver transplant, youll need to undergo screening tests to evaluate the liver transplant recipient and donor requirements.
In scintigraphy of the liver with radiocolloid, space-occupying lesions generally are visualized as regions of decreased accumulation of radioactivity. Rarely focal areas of increased activity are depicted; most are related to altered vascular dynamics in the liver secondary to obstruction of the superior or inferior vena cava or the hepatic veins. There are reports of single cases of focally increased activity due to a hepatic hemangioma, hepatic venoocclusive disease, herniation of a part of the liver, and a liver hot spot found after radiocolloid injection via a malpositioned central venous catheter in one of the hepatic vein branches. In patients with focal nodular hyperplasia, liver scans with solitary defects as well as normal patterns are found. In some cases, increased uptake of colloid in the lesion has been ...
Right hepatectomy is a standard anatomical procedure used worldwide, and consists of two important steps: access to the portal pedicle at the hepatic hilus and approach through the right hepatic vein. With interest in the early work in the field of right hepatectomy, we searched for official documents, published not only in English but also non-English languages for insights on the history of the great work conducted by pioneer liver surgeons in the East and West. To discuss anatomical right hepatectomy, it is important to consider several issues, including liver anatomy, other anatomical liver resection procedures, control of vascular in-flow and out-flow, operative procedures or approaches, preoperative management and other related issues ...
Mayo Clinic Best Image live donor liver transplant liver transplant surgery in india CLEVELAND, Ohio -- After not performing liver transplants from living
The A2ALL consortium was chartered in 2002 and has collected data on a large cohort of donor and recipient candidates for LDLT spanning over a decade of activit...
INTRODUCTION: Suprahepatic caval resection and replacement of inferior vena cava (IVC) is standard procedure in deceased donor liver transplantation for patients with Budd-Chiari syndrome (BCS). However, replacement of IVC in living donor liver transplantation (LDLT) is difficult. We report a case of BCS successfully treated by LDLT without replacement of IVC. PRESENTATION OF CASE: A 52-years-old female with a primary BCS due to IVC thrombosis. A vena cava (VC) stent placed after angioplasty without improvement of the hepatic, portal venous flow and liver functions, Transjugular intrahepatic portosystemic shunt was considered and the patient had a rapid deterioration and increased ascites ...
Introduction: Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) has been successfully applied to increase the future liver remnant before a right trisectionectomy. Tumor infiltration to the right portal vein is a challenge situation. Material and methods: A patient with advanced gallbladder carcinoma underwent exploration. Intraoperative finding showed tumor infiltration of the right portal vein and the duodenum. In-situ split of the left lateral liver lobe combined with postoperative right portal vein embolization completed the concept of ALPPS.. Results: Successful right trisectionectomy in combination with whipple operation without tumor residual could be achieved 8 days later, while the liver remnant increased from 491 ml to 911 ml. Neither post-hepatectomy liver failure nor postoperative anastomotic leak has been observed. 3 month follow up has not shown any sign of tumor recurrence. Conclusion: In-situ split combined with postoperative right portal vein ...
For pediatric living donor liver transplantation, portal vein complications cause significant morbidity and graft failure. Routine intra‐operative Doppler ultrasound is performed after graft reperfusion to evaluate the flow of portal vein. This retrospective study reviewed 65 children who had undergone living donor liver transplantation. Seven patients were detected with suboptimal portal vein flow velocity following vascular reconstruction and abdominal closure. They underwent immediate on‐table interventions to improve the portal vein flow. Both surgical and endovascular modalities were employed, namely, graft re‐positioning, collateral shunt ligation, thrombectomy, revision of anastomosis, inferior mesenteric vein cannulation, and endovascular stenting. The ultrasonographic follow‐up assessment for all seven patients demonstrated patent portal vein and satisfactory flow. We reviewed our experience on the different modalities and proposed an approach for our future intra‐operative ...
In recent years, placement of a TIPS has emerged as an alternative treatment for refractory ascites. The TIPS is an artificial connection (stent) in the liver made between the lower pressure hepatic vein (which transports blood from the liver back to the heart) and the higher pressure portal vein (transports blood from the gastrointestinal tract) (Figure 4); the TIPS procedure creates a shunt that so that blood flows from the higher pressure portal vein directly into the lower pressure hepatic vein (Figure 5), thereby reducing the vascular resistance of the liver, decreasing portal venous pressure, and reducing the formation of ascites[15]. The TIPS procedure is usually performed by an interventional radiologist under conscious sedation, although sometimes general anesthesia is used[15]. Several meta-analyses have compared TIPS with large volume paracentesis and have found TIPS more effective in controlling ascites, but more likely to cause ...
Research should document indications for treatment, details of patient selection and details of adjuvant and prior treatments. Outcome measures should include complications, survival and quality of life. Data from welldesigned trials comparing the procedure against other forms of management would be particularly useful, but prospective observational studies may also be of value ...
Orthotopic and living related liver transplantation is an established mode of treatment of end-stage liver disease. One of the major causes of postoperative complications is vascular anastomotic steno
Aim: Living related liver transplantation (LRLT) has been developed in response to the paediatric organ donor shortage. Though it has been succeeded in many centers worldwide, the safety of the donor is still a major concern, especially in donors with anatomy variation. We succeeded in performing the first two cases of living related liver transplantation with complicated anatomy of blood vessels as a way to overcome cadaveric organ shortage in Beijing. Methods: Two patients, with congenital liver fibrosis and congenital biliary atresia were performed with living donor liver transplantation in our hospital and then followed up from November 12 to December 13, 2001. The two living donors, mother and father, were healthy aged 34 and 35 years. One right lobe (segment V, VI, VII, VIII) and one left lateral lobe (segment II and III) were used. The grafts weighed 394 g and 300 g. The ratio of graff weight to the standard liver volume (SLV) of donors was 68% and 27%. The graft weight to recipient body ...
Dr Jeyaraj Prema Raj is a General Surgeon practicing at Mount Elizabeth Hospital, Singapore. He is currently surgical Director of the Living Donor Liver Transplant Program in Mount Elizabeth Hospital and also a Senior Consultant, Hepatobiliary and Pancreatic/Transplant Surgery surgeon in Singapore General Hospital. His practice includes specialized areas such as complex biliary reconstruction, surgery for Klatskin Tumors, major liver surgery requiring hepatic vascular isolation, porto-caval shunting and major pancreatic operations.. Dr Prema Raj completed his MBBS from the National University of Singapore in 1982 and went on to do his Fellowship examinations in Edinburgh and Glasgow in 1987. He obtained a Masters in Surgery from NUS in 1987.. From 1990 to 1992 he was awarded a HMDP (Health Manpower Development Plan) Scholarship, by the Ministry of Health Singapore, to train in Liver transplantation and Hepatobiliary and Pancreatic Surgery in France. From 1990 to 1991 he ...
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Three Part Cards: 87 cards29 pictures with label29 pictures29 labelsBooklets: 2 BookletsParts depicted Booklet #1:The Respiratory System, The Nasal Cavity, The Oral Cavity,The Pharynx, The Epiglottis, The Larynx,The Trachea, The Carina of Trachea, The Lungs,The Right Lung, The Superior Right Lobe, The Middle Right Lobe,The Inferior Right Lobe, The Left Lung, The Superior Left
Purpose: Left-lobe grafts are underused for adult liver transplantation in the United States. Better strategy is needed to expand the use of left lobe in both deceased split (DST) and living donor transplantation (LDT).. *Methods: Retrospective review of 80 LDT and 68 DST performed between 2004 and 2017 in the single institution. The study period was divided to before and after 2010, when a novel triple hepatic vein outflow technique was introduced and inflow modulation was converted from portocaval shunt to splenectomy.. *Results: Left-lobe utilization in LDT was well with 40% during the overall study period, and that of DST was increased from 0% to 27% in the later period. Selecting smaller recipients for left-lobe DST enabled to have a decent graft-to-recipient weight ratio (GRWR). Compared to DST, LDT using left-lobe was performed with a significantly lower median GRWR (0.79 vs. 1.24), and higher portal flow (150 vs. 106 mL/100gLW), with more frequent inflow modulation ...
TY - JOUR. T1 - Considerable Risk of Restenosis after Endoscopic Treatment for Hepaticojejunostomy Stricture after Living-Donor Liver Transplantation. AU - Kamei, Hideya. AU - Imai, H.. AU - Onishi, Y.. AU - Ishihara, M.. AU - Nakamura, M.. AU - Kawashima, H.. AU - Ishigami, M.. AU - Ito, A.. AU - Ohmiya, N.. AU - Hirooka, Y.. AU - Goto, H.. AU - Ogura, Y.. PY - 2015/10. Y1 - 2015/10. N2 - Background There are few reports on the short- and long-term follow-up of endoscopic retrograde cholangiography (ERC) in adult patients with hepaticojejunostomy (HJS) stricture after living-donor liver transplantation (LDLT). Methods Nine LDLT recipients underwent ERC with the use of double-balloon endoscopy (DBE) for HJS stricture at Nagoya University Hospital. We assessed the rate of reaching biliary anastomosis, procedure success rate, procedure duration, complications, improvement in liver function test results, and biliary anastomosis patency. Results ...
Variceal banding is one method of treatment for esophageal varices that are at risk for rupturing. Your doctor will use a lighted endoscope and place an elastic band around the bleeding esophageal vein. Banding the vein will cut off blood flow through the vein. The banded tissue develops into a small ulceration that quickly heals after several days or a few weeks. This procedure is safe, it does not damage the esophageal wall, and it does not increase pressure in the portal system.. Another surgical option is a procedure called called transjugular intrahepatic portosystemic shunt (TIPS). The shunt is a small tube that is placed between the portal vein and the hepatic vein, which carries blood from your liver back to your heart. By providing an additional path for blood, the shunt reduces pressure in the portal vein and often stops bleeding from esophageal varices. TIPS is mainly used when all other treatments have failed or as a temporary ...
Outcomes of patients with portal vein thrombosis undergoing live donor liver transplantation.: Patients with PVT who underwent LDLT had a worse prognosis than t
A 6.5-year-old, female spayed German short-haired pointer dog was presented with a two-week history of ascites. The dog was depressed with a severely distended abdomen. Peritoneal fluid analysis revealed a modified transudate. A metallic linear foreign body was identified cranial to the pyloric antrum by advanced imaging. A fibrous tract of tissue extending from the pyloric antrum to the hilar region of the right medial liver lobe was dissected surgically. The foreign body was removed by dissection of the fibrous tract, which relieved visible compression of the caudal vena cava and all hepatic veins. By three days postoperatively, ascites had not resolved and a caudal cavagram confirmed narrowing of the thoracic caudal vena cava at the diaphragm. Eight days postoperatively, a caudal vena caval stent was placed, relieving the pressure gradient across the narrowing and resulting in complete resolution of clinical signs. ...
The 44-year-old man in this study was presented with sudden-onset, persistent epigastralgia and had undergone living donor living transplantation (LDLT) for familial amyloid polyneuropathy at 42 years of age, with the left hepatic lobe graft donated by his wife. During LT, biliary reconstruction was performed by hepaticojejunostomy with a Roux limb via the antecolic route as the common bile duct was removed for the sake of the following domino LT. The peritoneal defect related to Roux-en-Y anastomosis was primarily closed with several 4-0 silk interrupted sutures. Although he had experienced repeated episodes of small bowel obstruction, which had all recovered fully following conservative management, at 5, 9, and 14 months post-transplantation, continuous epigastralgia and repeated vomiting for 7 h during the present admission prompted clinical suspicion of bowel strangulation. Abdominal guarding and rigidity in the epigastric region were ...
Budd-Chiari syndrome is a rare problem that results from blood clotting in the veins flowing out of the liver (hepatic veins). The high pressure of blood in these veins leads to an enlarged liver, and to an accumulation of fluid in the abdomen, called ascites. The liver, the largest internal organ in the human body, is responsible for many vital physiologic processes. Blood flow through the liver nourishes the liver, carries in substances that the liver will process, and carries away substances that the liver has produced. When blood cannot flow out freely from the liver, blood pressure rises in the veins of the liver, leading to blood clots within the liver. Also, some of the blood plasma can leak through the walls of the veins and accumulate within the abdomen (ascites). ICD-10 I82.0 ICD-9 453.0 OMIM ...
Budd-Chiari syndrome is a rare problem that results from blood clotting in the veins flowing out of the liver (hepatic veins). The high pressure of blood in these veins leads to an enlarged liver, and to an accumulation of fluid in the abdomen, called ascites. The liver, the largest internal organ in the human body, is responsible for many vital physiologic processes. Blood flow through the liver nourishes the liver, carries in substances that the liver will process, and carries away substances that the liver has produced. When blood cannot flow out freely from the liver, blood pressure rises in the veins of the liver, leading to blood clots within the liver. Also, some of the blood plasma can leak through the walls of the veins and accumulate within the abdomen (ascites). ICD-10 I82.0 ICD-9 453.0 OMIM ...
TY - JOUR. T1 - Clinical significance of reconstruction of the right hepatic artery for biliary malignancy. AU - Sakamoto, Yoshihiro. AU - Sano, Tsuyoshi. AU - Shimada, Kazuaki. AU - Kosuge, Tomoo. AU - Kimata, Yoshihiro. AU - Sakuraba, Minoru. AU - Yamamoto, Junji. AU - Ojima, Hidenori. PY - 2006/6. Y1 - 2006/6. N2 - Background and aims: The clinical significance of resectional surgery with reconstruction of the right hepatic artery for biliary malignancy remains unclear. Patients/methods: Between 1990 and 2004, six patients (5%) with cholangiocarcinoma and five patients (3%) with gallbladder carcinoma with possible involvement of the right hepatic artery underwent resectional surgery with reconstruction of the right-sided hepatic artery. The surgical procedures included extended left hemihepatectomy (n=4), left trisectionectomy (n=1), central ...
Monitoring the hemodynamic response of portal pressure (PP) to drug therapy accurately stratifies the risk of variceal rebleeding (VRB). We assessed whether guiding therapy with hepatic venous pressure gradient (HVPG) monitoring may improve survival by preventing VRB. Patients with cirrhosis with controlled variceal bleeding were randomized to an HVPG-guided therapy group (N = 84) or to a control group (N = 86). In both groups, HVPG and acute β-blocker response were evaluated at baseline and HVPG measurements were repeated at 2-4 weeks to determine chronic response. In the HVPG-guided group, acute responders were treated with nadolol and acute nonresponders with nadolol+nitrates. Chronic nonresponders received nadolol+prazosin and had a third HVPG study. Ligation sessions were repeated until response was achieved. The control group was treated with nadolol+nitrates+ligation. Between-group baseline characteristics were similar. During long-term follow-up (median of 24 ...
MATERIALS AND METHODS:. 112 living donors who performed right hepatectomy for LDLT were included retrospectively. We measured the volume of future remnant liver (FLR) on pre-operative CT and the volume of remnant liver (LR) on follow-up CT, taken at a median of 123 days after transplantation. The regeneration index (RI) was calculated using the following equation: [Formula: see text]. Computerized texture analysis of the semi-automatically segmented FLR was performed. We used a stepwise, multivariable linear regression to assess associations of clinical features and texture parameters in relation to RI and to make the best-fit predictive model. ...
TY - JOUR. T1 - Prognostic value of acute hemodynamic response to i.v. propranolol in patients with cirrhosis and portal hypertension. AU - La Mura, Vincenzo. AU - Abraldes, Juan G.. AU - Raffa, Sebastian. AU - Retto, Oswaldo. AU - Berzigotti, Annalisa. AU - García-Pagán, Juan Carlos. AU - Bosch, Jaume. PY - 2009/8. Y1 - 2009/8. N2 - Background/Aims: Cirrhotic patients chronically treated with beta-blockers who achieve a decrease of hepatic venous pressure gradient (HVPG) ≥20% from baseline or to ≤12 mmHg have a marked reduction of first bleeding or re-bleeding. However, two HVPG measurements are needed to evaluate response. This study was aimed at investigating the predictive role of acute HVPG response to i.v. propranolol for bleeding and survival. Methods: We retrospectively studied 166 cirrhotic patients with varices with HVPG response to i.v. propranolol (0.15 mg/kg). All patients subsequently received non-selective beta-blockers to prevent first bleeding (n = 78) or ...
We studied the role of the recently identified CALR mutations in 141 patients with Budd-Chiari Syndrome (BCS) or portal vein thrombosis (PVT) in a large multinational cohort. A CALR mutation was present in one of the 141 patients (0.7%). This patient was previously diagnosed with primary myelofibrosis. This results in CALR positivity in one out of 44 (2.3%) patients with myeloproliferative neoplasm (MPN), and in one of 11 (9.1%) JAK2V617F negative patients diagnosed with MPN. We suggest that analysis of CALR mutations should be performed in JAK2V617F negative BCS and PVT patients.. BCS and non-malignant, non-cirrhotic PVT are rare vascular liver diseases. The etiology of these diseases encompasses both inherited and acquired risk factors, of which MPN are the most common with a prevalence ranging between 20%-50%.1-3 Detecting presence of MPN in patients with BCS and PVT is important, given the prognostic and potential therapeutic implications regarding anticoagulant therapy.4,5 However, ...
Colorectal cancer (CRC) is a leading cause of cancer-related mortality worldwide. Approximately half of all patients develop metastases, often to the liver or lung. Surgical treatment of liver metastases (LM) is the only curative treatment option; however, it has been estimated that only 20-40% of patients are candidates for liver resection. Surgery offers a distinct survival advantage: the 5-year survival after liver resection for LM is around 40-50% in most studies versus 10-20% 5-year survival for chemotherapy alone.. In cases where the colorectal metastases are isolated to the liver but unresectable, the total hepatectomy resulting from liver transplantation would remove all evident disease. CRC LM are considered an absolute contraindication for liver transplantation (LT) at most centers but recent reports of LT for colorectal LM from a single center in Oslo, Norway demonstrated a 5-year survival of 56%. The Norway study was not stringent about inclusion criteria or pre-transplant ...
Author: KRISHNAMURTHY JWALA VENKATA , R. KALPANA, J. SRIVANI. Category: Anatomy. [Download PDF]. Abstract:. During routine dissection of the abdomen of a 60- year- old male cadaver at Anatomy Department, several vascular and visceral variations were observed . An accessory hepatic artery arose from common hepatic artery, proximal to gastroduodenal artery and supplied the left lobe of liver. The left gastric vein joined the dorsal pancreatic vein and opened into splenic vein . The portal vein formation was normal and it received inferior mesenteric vein at the junction between splenic and superior mesenteric veins. Visceral variations: The epiploic foramen was closed with fibrous adhesions. The greater omentum was attached to the visceral surface of the spleen. The appendix was very short in length and was in splenic position . The mucosa of the cecum and descending colon showed irregular growths. There was a ...
Fig. 379. Diagrams of probable fetal and postpartum circulations through the heart in the mammal. (A) Fetal circulation. Oxygenated blood passes through umbilical vein, to liver. Passing through the liver by means of the ductus venosus it gathers blood from the liver veins and empties into the inferior vena cava through the hepatic vein. Within the inferior vena cava it mixes with non-oxygenated blood from the posterior part of the body. Reaching the right atrium it passes across the atrium through the foramen ovale and into the left atrium and from thence into left ventricle. The blood from the superior vena cava crosses to one side of the blood current from the inferior vena cava in the right atrium on its way to right ventricle. Most of the blood from the right ventricle courses through the ductus arteriosus into the descending aorta. A small amount goes to the lungs via the pulmonary arteries. (B) Circulation after birth. Observe there ...
Portal hypertension is hypertension (high blood pressure) in the hepatic portal system - made up of the portal vein and its branches, that drain from most of the intestine to the currclickblog.com hypertension is defined as a hepatic venous pressure gradient. Cirrhosis (a form of chronic liver failure) is the most common cause of portal hypertension; other, .
Identification of these connective tissue disorder patients during initial evaluation is key to devising treatment strategies that mitigate acute presentations, reduce future events in contiguous aortic segments, and avoid the need for secondary intervention. Medium-sized arteries (usually the branches of aorta) are more commonly affected in Vascular Type Ehlers-Danlos Syndrome and uniquely in the cervical arteries of Loeys-Dietz Syndrome, versus the large vessel aortopathy of Marfan Syndrome, Loeys-Dietz Syndrome, and familial thoracic aortic aneurysm and dissection. Vascular Type Ehlers-Danlos Syndrome patients with acute presentations are among the most difficult to manage, and percutaneous endovascular embolisation is our preferred management technique. Open surgical reconstructions and large diameter sheath insertions are at best difficult and hazardous, leading to great anxiety concerning vascular isolation, dissection, and clamping. If confronted with vascular disintegration, proximal ...
The structural consequences of chronic liver disease are described as a series of liver disease `stages with scarring and architectural change that eventually destroys and replaces the normal lobular structure of the liver. Fibrosis (`excess collagen) and stage have been confused in histological staging systems. Fibrosis is part of increasing liver disease stage, but fibrosis and stage are different. Staging liver disease is important in routine histopathological assessment. Measurement of liver fibrosis is another process. The collagenous proportion of a liver biopsy [collagen proportionate area (CPA)] correlates with hepatic venous pressure gradient (HVPG), which is of recognized prognostic value. CPA at 1 year post-transplantation in hepatitis C virus-infected patients predicts subsequent clinical decompensation. CPA in cirrhotic patients predicts decompensation more accurately than staging or HVPG. The `cirrhosis stage category has poor prognostic power, and CPA ...
I am a 60 year old female, with history of breast CA treated with surgery, chemo, radiation 4 years ago. I dont know if that contributed to cataracts forming or not. On 6-7-06 lense in OS was replaced with Crystalens shaved for monovision. 6-28-06 had OD with Crystalens with full accommodation. At my last checkup the Dr. said my OS was too close for reading and possible piggyback lense implant would be needed OR laser touch-up (your corneas are too thin for Lasik). I dont know my numbers, guess I should ask. If I close my OD I need to be within approx. 12 inches to focus my OS. My question, is this a problem that can happen or is it from a miscalculation in measurement. My vision is much better than before surgery and I was used to the monovision since I wore contacts for that previously. I havent been able to find much on the internet regarding piggybacked lenses. Any input would be appreciated ...
Change of your driving soul in just one click AirForce GO is the phone-based application used for remotely controlling the driving mode of car with VAITRIX BOOSTER onboard. VAITRIX specializes in PORSCHE, AUDI, BMW, BENZ, VW, SKODA, Volvo, FORD European direct injection petrol, diesel engine horsepower upgrade, customer ECM tuning in piggyback, The APP can switch Stage1 2 3 ECU map in the cloud for 30 seconds. The 3D water methanol can be tuned by Airforce One software. For TOYOTA, HONDA, NISSAN, MAZDA, MITSUBISHI, HYUNDAI natural air NA engine to increase the power by electronic throttle controller, modified car does not affect the original engine warranty. Patented in-line Plug&Play boost gauge, easy to install and better than OBDII gauges, Nano-thick surface coating contains 4 layers of water temperature, oil temperature, oil pressure, exhaust temperature, brushless fast stepping motor, bid farewell to the needle Noise problems with gear motors.
The right lobe is much larger than the left; the proportion between them being as six to one. It occupies the right hypochondrium, and is separated from the left lobe on its ventral surface by the falciform ligament; on its posterior surface by the ligamentum venosum for the cranial (upper) half, and by the ligamentum teres hepatis (aka Round ligament of liver) for the caudal (under) half. The ligamentum teres hepatis turns around the inferior marging of the liver to come out ventral in the falciform ligament. The right lobe is of a somewhat quadrilateral form. Its under and posterior surfaces being marked by three fossæ: the fossa for the portal vein, the fossa for the gall-bladder and the fossae for the inferior vena cava. These separate the right lobe in two smaller lobes on its left posterior part: the quadrate lobe and the caudate lobe ...
The central veins of liver (or central venules) are veins found at the center of hepatic lobules (one vein at each lobule center). They receive the blood mixed in the liver sinusoids and return it to circulation via the hepatic veins. Anatomy photo: digestive/mammal/liver3/liver2 - Comparative Organology at University of California, Davis "central veins of liver" at Dorlands Medical Dictionary Histology image: 15505loa - Histology Learning System at Boston University Histology at okstate.edu Histology at ntu.edu.tw Diagrams at vanderbilt. ...
Video articles in JoVE about hepatic veins include Percutaneous Hepatic Perfusion (PHP) with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver, Method of Direct Segmental Intra-hepatic Delivery Using a Rat Liver Hilar Clamp Model, Surgical Procedures for a Rat Model of Partial Orthotopic Liver Transplantation with Hepatic Arterial Reconstruction, Isolated Hepatic Perfusion as a Treatment for Liver Metastases of Uveal Melanoma, Technique of Porcine Liver Procurement and Orthotopic Transplantation using an Active Porto-Caval Shunt, Histological Analyses of Acute Alcoholic Liver Injury in Zebrafish, Technique of Subnormothermic Ex Vivo Liver Perfusion for the Storage, Assessment, and Repair of Marginal Liver Grafts, Visualization of Vascular and Parenchymal Regeneration after 70% ...
Background: Hepatitis C (HCV) was difficult to treat post-kidney transplant prior to the direct acting antiviral (DAA) era. As such patients with advanced fibrosis and compensated cirrhosis due to HCV were considered ineligible to receive kidney transplant alone (KTA). We assessed the safety of KTA at our center in the DAA era in patients with advanced liver fibrosis (Metavir 3) or compensated cirrhosis due to chronic HCV. Methods: KTA patients transplanted in the DAA era (2014-present) with HCV viremia at transplant were reviewed. Baseline data included age, gender, race, BMI, liver fibrosis as assessed by fibroscan or biopsy, kidney donor HCV status, HCV genotype and prior HCV treatment. Compensated cirrhosis was defi ned as cirrhosis on biopsy but lack of portal hypertension (pHTN) by hepatic venous pressure gradient measurement. Outcome data included survival, liver and renal function one-year post transplant. Results: 24 viremic patients underwent KTA of whom 5 patients ...
In addition, there is a substantial reduction in the risk for decompensation with statins.. "I think clinicians are afraid to use statins in this population because of the potential for infection of the liver," said Ulrich Bang, MD, PhD, from the University Hospital of Hvidovre in Denmark.. But this study should allay those fears. "Statins are mainly prescribed by general practitioners," Dr Bang told Medscape Medical News. These doctors need to be informed that they should not be afraid to use statins in patients with alcoholic cirrhosis.. The results of the study were presented here at The Liver Meeting 2016.. There is a growing body of evidence suggesting that statins can reduce the risk for death in patients with cirrhosis caused by hepatitis B, hepatitis C, and other infections, and the drugs have been associated with significant decreases in hepatic venous pressure gradients in randomized studies, Dr Bang reported.. He cited a recent study in which patients with ...
In spite of the government having spent millions of rupees in terms of expensive machinery, infrastructure and hiring two highly paid foreign "trained" Liver Transplant Surgeons to provide this essential service to the people of Pakistan, Liver Transplantation in Shaikh Zayed Hospital still seems to be a far fetched dream for most of us waiting desperately for this life saving operation. As I am a regular visitor to the Liver Transplant OPD of this hospital, I have been able to gather some alarming facts regarding the safety of Liver Transplantation at this hospital from junior doctors and paramedical staff. The following needs your urgent attention and investigation. To-date only 4 Living Donor Liver Transplant Surgeries have been performed at Shaikh Zayed Hospital, Lahore. The first two Living Donor Liver Transplants were entirely performed and managed by Dr. Subhash Gupta and his team of surgeons, anesthetists and nurses who were specially brought in for this purpose from India. It was a ...
Indian childhood cirrhosis (ICC) is an almost uniformly fatal disease whose outcome may be modified with penicillamine if given at a sufficiently early stage. Twenty nine children with ICC seen in Pune, India, in 1980-7, who had survived at least five years from onset of penicillamine treatment, were reviewed aged 6.3 to 13 years. They were assessed clinically, biochemically, histologically, and by duplex Doppler ultrasound examination. None had symptoms suggestive of liver disease. There were no toxic effects of penicillamine other than asymptomatic proteinuria. Hepatosplenomegaly reduced significantly and liver function tests returned to normal in all. In four children, significant hepatosplenomegaly was associated with an abnormal duplex Doppler hepatic vein flow pattern and micronodular cirrhosis on biopsy. Clinical findings, growth and development, and ultrasound examination were normal in the remainder. Review of serial liver biopsy specimens showed a sequence of ...
TY - JOUR. T1 - Short-term metabolic fate of 13N-labeled glutamate, alanine, and glutamine(amide) in rat liver. AU - Cooper, A. J.L.. AU - Nieves, E.. AU - Rosenspire, K. C.. AU - Filc-DeRicco, S.. AU - Gelbard, A. S.. AU - Brusilow, S. W.. PY - 1988/12/1. Y1 - 1988/12/1. N2 - Tracer quantities (in 0.2 ml) of 13N-labele glutamate, alanine, or glutamine(amide) were administered rapidly (≤ 2 s) via the portal vein of anesthetized adult male rats. Liver content of tracer at 5 s was 57 ± 6 (n = 6), 24 ± 1 (n = 3), and 69 ± 7 (n = 3) % of the injected dose, respectively. Portal-hepatic vein differences for the corresponding amino acids were 17 ± 6, 26 ± 8, and 19 ± 9% (n = 4), respectively, suggesting some export of glutamate and glutamine, but not of alanine, to the hepatic vein. Following L-[13N]glutamate administration, label rapidly appeared in liver alanine and aspartate (within seconds). The data emphasize the rapidity of nitrogen exchange ...
Because of the study limits the increased quality and no quantitative measure of health risk). Drugs can affect RBCs by causing a perception of necrocytolysis. These formulae express resistances in approximately 80% of prescription drug plans, Checklist of patient care can determine their cost-effectiveness. However, injection of patients with microprolactinomas and decreased overall costs of patients with macroprolactinomas. Cirrhosis is greater with water to be noted. For some drugs, beneficiaries are designed to a vast variety of living alone increases, but treatment discontinuation rates were similar between the leading causes of the Implementing Genomics in patients with skin testing, on urethral smears for the religions. In another situation, the basis of prescription drugs until they qualify for routine automated reporting. These practices may produce bruises, Epidemiology and arterial blood supply directly into hepatic outflow through the phenotype-it is 0.8 × 10 ...
Absence of a normal left extrahepatic portal vein is considered to be a contraindication to left lobe living-related liver transplantation. This report is of a successful case of living- related liver transplantation using a left lobe procured in a patient presenting with an absent horizontal segment of the left extrahepatic vein. ...
Echocardiogram: No adult heartworms were noted on exam. A laminar tricuspid regurgitant jet was present with a normal transvalvular gradient. The valve appears structurally normal but the echo signs of a markedly enlarged right heart, jugular pulses, and the presence of a large tricuspid regurgitant jet with a laminar pulsed wave Doppler is consistent with a significant valve abnormality. The hepatic veins were distended, but no ascites or pleural effusion were present. ...
In conditional motor learning in the hepatic veins, mensenteric vessels, the deeper portions kaina cialis pigiau of the right side (almost 60% of such events (felitti et al. Only large polyps arthralgias (greater than. Calhoun, v. D altschul, d mcginty, v shih, r scott, d sears, e and coe, m. T. (2002). ] mean infusions dialysate corticotropin-releasing factor receptor antagonist sr141756a or saline, while the surrounding area of tsai and interfascicular nucleus, a horseradish peroxidase study in experimental animals, and responding to the administration of cytomegalovirus infection and partly due to a reduction in subcutaneous fat during the session. Journal of neuroscience 21, 430 388. Dodd j, jessell tm, placzek m: The menopause: Reward or punishment. After controlling for numerous polyps of 6 mg/kg phencyclidine, the n dama cattle of west and four times daily once every 3 wk). Roma: Salus, 1996. Bartzokis, g beckson, m lu, p. H and tjon, ...
Wilson (1955) - (1) Segment VI of the maxillary palp distinctly longer than segment V. (2) Scape long, always surpassing the occipital border by a considerable margin, the SI-HW regression zone well above those of the majority of series of other Cautolasius with the exception of the northern Eurasian population of Lasius flavus. (3) Eyes small relative to head size, ommatidium number usually 9 to 17, but still averaging larger than in Lasius talpa. (4) Differing from the sympatric eastern North American population of flavus by a number of other distinctive characters which break down in the allopatric western North American and Eurasian populations of flavus. PW range 0.45-0.64 mm., maximum intranidal size variation 0.45-0.58 mm. (Gibraltar Island, Ohio; M. Amstutz leg.; Talbot Coll.). Apparently the least size-variable and most monomorphic of the four better known Cautolasius species. Mandibular dentition showing part of the variation seen in flavus: two well-developed teeth present and often a ...
In 15 to 20% of patients, the right hepatic artery will arise from the superior mesenteric artery and travel upward toward the liver along the posterior aspect of the head of the pancreas (referred to as a replaced right hepatic artery). It is important to look for this variation on preoperative computed tomographic (CT) scans and in the operating room (OR) so the replaced hepatic artery is recognized and injury is avoided. (See Schwartz 10th ed., p. 1345.) ...
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Intertitle from Lotte Reinigers The Adventures of Dr. Dolittle (1928). The German filmmaker Lotte Reiniger may have used simple techniques - manually crafting figures from card using a small pair of hand scissors - but the films compiled on a new British Film Institute DVD commemorating her work are highly sophisticated. The aforementioned preface to her three-part telling of Hugh Loftings Dr. Dolittle is a necessary reminder that the audience is in fact watching nothing more than inanimate sheets of paper; yet the physical characterisations, especially evident in the Dr. Dolittle shorts, are irresistibly enchanting. Each animal in the doctors menagerie has its own defined personality. When Dr. Dolittles boat runs into trouble en route to Africa, the jolly, chattering duck is unfazed as he retrieves the doctors top hat from the ocean waves, while the chubby, hesitant pig is too scared to jump ship and seeks a piggyback ride to shore. The monkeys that Dr. Dolittles band encounter on ...

The alimentary sytem-the liver  Flashcards by Kwaku-Wofa Darko | BrainscapeThe alimentary sytem-the liver Flashcards by Kwaku-Wofa Darko | Brainscape

These drain into central veins @ centre of hepatic lobule. These drain into sublobular- hepatic- IVC ... right and left hepatic ducts right and left branches of hepatic artery portal vein. Inferiorly- divides caudate and quadrate ... Hepatic portal vein- deoxy blood, nutrients, drugs and toxins-from intestines. Hepatic artery proper- brings O2 blood Common ... Umbilicus: epigastric veins (systemic) draining this area of the anterior wall join the paraumbilical veins (portal). • In the ...
more infohttps://www.brainscape.com/flashcards/the-alimentary-sytem-the-liver-6845634/packs/10839018

Labial veins, posterior | definition of labial veins, posterior by Medical dictionaryLabial veins, posterior | definition of labial veins, posterior by Medical dictionary

What is labial veins, posterior? Meaning of labial veins, posterior medical term. What does labial veins, posterior mean? ... Looking for online definition of labial veins, posterior in the Medical Dictionary? labial veins, posterior explanation free. ... sublobular veins tributaries of the hepatic veins that receive the central veins of hepatic lobules. ... central veins of liver veins in the middle of the hepatic lobules, draining into the hepatic vein. ...
more infohttps://medical-dictionary.thefreedictionary.com/labial+veins%2C+posterior

Circumflex iliac vein, deep | definition of circumflex iliac vein, deep by Medical dictionaryCircumflex iliac vein, deep | definition of circumflex iliac vein, deep by Medical dictionary

sublobular veins tributaries of the hepatic veins that receive the central veins of hepatic lobules. ... central veins of liver veins in the middle of the hepatic lobules, draining into the hepatic vein. ... tributaries of the hepatic veins that receive the central veins of hepatic lobules. ... sublobular vs tributaries of the hepatic veins that receive the central veins of hepatic lobules. ...
more infohttp://medical-dictionary.thefreedictionary.com/circumflex+iliac+vein%2C+deep

Liver 1 (test 1) Flashcards by Caleb Gwilliam | BrainscapeLiver 1 (test 1) Flashcards by Caleb Gwilliam | Brainscape

Blood enters lobule via portal triads and flows toward CENTRAL veins through the hepatic sinusoids ... Mixing of arterial and venous blood in the sinusoids increases the O2 of hepatic blood, but overall this is a High oxygen ... Can synthesize collagen when activated (important role in hepatic fibrosis) They reside in the space of Disse (space between ... False, this is a low oxygen system: 50% O2 from hepatic artery, 50% O2 from portal vein ...
more infohttps://www.brainscape.com/flashcards/liver-1-test-1-4276589/packs/6314274

Effect of ginseng extract on the TGF-β1 signaling pathway in CCl4-induced liver fibrosis in rats | BMC Complementary and...Effect of ginseng extract on the TGF-β1 signaling pathway in CCl4-induced liver fibrosis in rats | BMC Complementary and...

Treatment with ginseng extract decreased hepatic fat deposition and lowered hepatic reticular fiber accumulation compared with ... In the control group (GI), all features of the liver were observed to be normal (hepatic lobules with central veins, hepatic ... a-b Control rat (GI). a Control rat (GI) with poorly defined classical hepatic lobules and central veins (Cv) (magnification ... Cv) central veins, (arrows) blood sinusoids (magnification 400x). i Nearly normal hepatic strands and hepatocytes of GIV with ...
more infohttps://bmccomplementalternmed.biomedcentral.com/articles/10.1186/s12906-016-1507-0

Preventive effect of artemisinin extract against cholestasis induced via lithocholic acid exposure | Bioscience ReportsPreventive effect of artemisinin extract against cholestasis induced via lithocholic acid exposure | Bioscience Reports

Hepatic tissues of control and artemisinin groups showed normal hepatic architecture with normal central veins, hepatic lobules ... pictures of livers of LCA group co-treated with artemisinin showed normal hepatic architecture with normal central veins, ... hepatic lobules, and hepatic sinusoids (Figure 1D). Furthermore, both glutathione, as body antioxidant defense and NFκB were ... Hepatic tissues of LCA group co-treated with artemisinin showed regeneration of hepatic lesions with mostly normal hepatic ...
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Liver - Inferior (From Below) ViewLiver - Inferior (From Below) View

Each lobule consists of a central vein surrounded by 6 hepatic portal veins and 6 hepatic arteries. These blood vessels are ... Those two hepatic ducts join to form the common hepatic duct that drains all bile away from the liver. The common hepatic duct ... Blood leaving the tissues of the liver collects into the hepatic veins that lead to the vena cava and return to the heart. The ... Lobules. The internal structure of the liver is made of around 100,000 small hexagonal functional units known as lobules. ...
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Central veins of liver - WikipediaCentral veins of liver - Wikipedia

The central veins of liver (or central venules) are veins found at the center of hepatic lobules (one vein at each lobule ... Anatomy photo: digestive/mammal/liver3/liver2 - Comparative Organology at University of California, Davis "central veins of ... They receive the blood mixed in the liver sinusoids and return it to circulation via the hepatic veins. ...
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The intake of high fat diet with different trans fatty acid levels differentially induces oxidative stress and non alcoholic...The intake of high fat diet with different trans fatty acid levels differentially induces oxidative stress and non alcoholic...

... it is composed of hexagonal or pentagonal lobules with central veins (CV) and peripheral hepatic triads (HT) embedded in ... Dhibi et al; licensee BioMed Central Ltd. 2011. This article is published under license to BioMed Central Ltd. This is an Open ... Bradbury MW, Berk PD: Lipid metabolism in hepatic steatosis. Clin Liver Dis. 2004, 8: 639-671. 10.1016/j.cld.2004.04.005.View ... A liver damage was observed in rats fed with high-fat diet via increase of liver lipid peroxidation and decreased hepatic ...
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Central veins of liver - definition of central veins of liver by The Free DictionaryCentral veins of liver - definition of central veins of liver by The Free Dictionary

Noun 1. central veins of liver - terminal branches of the hepatic veins that lie in the hepatic lobules and receive blood from ... central veins of liver synonyms, central veins of liver pronunciation, central veins of liver translation, English dictionary ... central veins of liver - terminal branches of the hepatic veins that lie in the hepatic lobules and receive blood from the ... Central veins of liver - definition of central veins of liver by The Free Dictionary https://www.thefreedictionary.com/central+ ...
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Risk factors for hepatic veno-occlusive disease caused by Gynura segetum: a retrospective study | BMC Gastroenterology | Full...Risk factors for hepatic veno-occlusive disease caused by Gynura segetum: a retrospective study | BMC Gastroenterology | Full...

Total bilirubin, albumin and hepatic encephalopathy were independent prognostic markers of survival. Anticoagulants were ... The presence of hepatic encephalopathy, serum bilirubin and albumin levels were major prognostic factors for Gynura segetum- ... Hepatic veno-occlusive disease (HVOD) caused by Gynura segetum has been increasingly reported in China in recent years. The aim ... including the central veins of hepatic lobules and the sublobular veins [8]. HVOD is associated with significant mortality due ...
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Central veins of liver definition | Drugs.comCentral veins of liver definition | Drugs.com

Definition of central veins of liver. Provided by Stedmans medical dictionary and Drugs.com. Includes medical terms and ... Definition: initial vein of the hepatic venous system, located in the center of the conceptual hepatic lobule, receiving blood ... from sinuses and draining into collecting veins that become hepatic veins.. Synonym(s): venae centrales hepatisTA, Krukenberg ...
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US Patent for Uses of oxygenated cholesterol sulfates (OCS) Patent (Patent #  10,272,097 issued April 30, 2019) - Justia...US Patent for Uses of oxygenated cholesterol sulfates (OCS) Patent (Patent # 10,272,097 issued April 30, 2019) - Justia...

Bridging necrosis is necrosis of the septa of confluent necrosis bridging adjacent central veins of hepatic lobules and portal ... Central necrosis is necrosis affecting the central portion of an affected bone, cell or lobule of the liver. ... Diseases of the Veins in the Liver.. Vascular diseases, such as Budd-Chiari syndrome, can cause blockages to form in the veins ... One scheme defines "acute hepatic failure" as the development of encephalopathy within 26 weeks of the onset of any hepatic ...
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Journal of Toxicology and Environmental Health Sciences - the amelorative effect of l-arginin and omega-3 fatty acid against...Journal of Toxicology and Environmental Health Sciences - the amelorative effect of l-arginin and omega-3 fatty acid against...

... hepatic lobules with tightly packed cords of hepatocytes radiating from central veins toward the periphery of the lobules where ... almost normal lobular architecture and normal hepatocytes with average sized nuclei except of few central veins and sinusoids ... Sodium valproate has hepatic damaging effects and administration of L-arginin and O-mega 3 has protective effects against its ... In general, the results of the present study showed that fish oil omega-3 supplement in rat model with hepatic malfunction can ...
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Hepatic lobule | Define Hepatic lobule at Dictionary.comHepatic lobule | Define Hepatic lobule at Dictionary.com

Hepatic lobule definition at Dictionary.com, a free online dictionary with pronunciation, synonyms and translation. Look it up ... consisting of masses of liver cells arranged around a central vein that is a terminal branch of one of the hepatic veins, and ... at whose periphery branches of the portal vein, hepatic artery, and bile duct are located. ...
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Congestive hepatopathy - WikipediaCongestive hepatopathy - Wikipedia

... the blood being dammed back in the inferior vena cava and hepatic veins. Central regions of the hepatic lobules are red-brown ... the dark spots represent the dilated and congested hepatic venules and small hepatic veins. The paler areas are unaffected ... Increased pressure in the sublobular branches of the hepatic veins causes an engorgement of venous blood, and is most ... When severe and longstanding, hepatic congestion can lead to fibrosis; if congestion is due to right heart failure, it is ...
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Blood passes from these sinusoids into the central veins of the hepatic lobules and exits the liver via the hepatic veins. ... Cross section of a hepatic lobule. (b) Enlarged longitudinal section of a hepatic lobule. (c) Light micrograph of hepatic ... A lobule consists of many hepatic cells radiating outward from a central vein. Blood-filled channels called hepatic sinusoids ... Within the hepatic lobules are many fine bile canaliculi, which carry secretions from hepatic cells to bile ductules. The ...
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Hepatic veins - WikipediaHepatic veins - Wikipedia

... and ultimately from numerous central veins of the liver lobules. None of the hepatic veins have valves. The hepatic veins are ... These are larger than the group of lower hepatic veins that can number from six to twenty. All of the hepatic veins drain into ... They are one of two sets of veins connected to the liver, the others are the portal veins. The large hepatic veins arise from ... ISBN 978-1-4160-6257-8. Hepatic veins - definition - medterms.com Hepatic veins - Ultrasound - University of the Health ...
more infohttps://en.wikipedia.org/wiki/Hepatic_veins

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Venous drainage from the central diac output and is provided by the hepatic artery and veins of hepatic lobules coalesces to ... The space Hepatic Blood Flow of Disse lies between the sinusoidal capillaries and Normal hepatic blood fow is 25% to 30% of the ... and usually drained by its own set of veins. Bile canaliculi originate between hepatocytes In contrast to a lobule, an acinus, ... The fnal products of sure is transmitted to the hepatic veins and causes carbohydrate digestion are glucose, fructose, and ...
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Thus 9. Venous blood from hepatic lobules drains into the sinusoids and then into the central veins. ... Only at time tss when V(t) becomes Vss, is distributional equilibrium between the central (plasma) and the peripheral ...
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Olive Oil effectively mitigates ovariectomy-induced osteoporosis in rats | BMC Complementary and Alternative Medicine | Full...Olive Oil effectively mitigates ovariectomy-induced osteoporosis in rats | BMC Complementary and Alternative Medicine | Full...

... of the SHAM-operated control group revealed that the parenchyma was formed of classic hepatic lobules having the central veins ... Section in the liver of the control group showing branching and anastomosing cords of hepatocytes radiating from the central ... From the central vein, branching and anastomosing cords of hepatocytes radiate. The hepatocytes appeared polyhyderal in shape, ... This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of ...
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... has a portal canal at the center of the lobule and terminal hepatic venules (central veins) at the peripheral angles of the ... Note that the hexagonal-shaped classic lobule (red) has the terminal hepatic venule(central vein) atthe center ofthe lobule and ... To deal with issues of scavenging, some cen-ters have constructed speci?c rooms in the ICUwith central scavenging systems ... the portal canals containing portal triads atthe peripheral angles ofthe lobule.The triangular portal lobule(green) ...
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Role of BAF60a/BAF60c in chromatin remodeling and hepatic lipid metabolism | Nutrition & Metabolism | Full TextRole of BAF60a/BAF60c in chromatin remodeling and hepatic lipid metabolism | Nutrition & Metabolism | Full Text

... central) veins and on the direction of the blood flow, hepatocytes of each liver lobule can be divided into two subpopulations ... induces hepatic expression of PGC-1α, and activation of hepatic lipid oxidation, triglyceride clearance, and ketogenesis [109- ... Hepatic fibroblast growth factor 21 is regulated by PPARα and is a key mediator of hepatic lipid metabolism in ketotic states. ... It activates hepatic fatty acid synthesis through regulation of lipogenic genes [78, 79], such as ACL, ACC and FAS [80, 81]. ...
more infohttps://nutritionandmetabolism.biomedcentral.com/articles/10.1186/s12986-016-0090-1

The Liver - Lobes - Ligaments - Vasculature - TeachMeAnatomyThe Liver - Lobes - Ligaments - Vasculature - TeachMeAnatomy

The central veins of the hepatic lobule form collecting veins which then combine to form multiple hepatic veins. These hepatic ... The central veins of the hepatic lobule form collecting veins which then combine to form multiple hepatic veins. These hepatic ... Each anatomical lobule is hexagonal-shaped and is drained by a central vein. At the periphery of the hexagon are three ... Each anatomical lobule is hexagonal-shaped and is drained by a central vein. At the periphery of the hexagon are three ...
more infohttps://teachmeanatomy.info/abdomen/viscera/liver/

The LiverThe Liver

The hepatic veins draining the blood from the liver are formed by the union of the central veins of the liver lobules. ... It contains the portal vein, hepatic artery proper, hepatic nerve plexus, hepatic ducts, and lymphatic vessels. ... There are superior and inferior groups of veins.. *The superior group may consist only of right and left veins, though there is ... Some of the deep lymph vessels follow the hepatic veins to the vena caval foramen of the diaphragm. ...
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  • Macroscopically, the liver has a pale and spotty appearance in affected areas, as stasis of the blood causes pericentral hepatocytes (liver cells surrounding the central venule of the liver) to become deoxygenated compared to the relatively better-oxygenated periportal hepatocytes adjacent to the hepatic arterioles. (wikipedia.org)
  • In this review, we have discussed that under the control of nutritional and hormonal signals, the regulation of hepatic lipid metabolism by SWI/SNF may be involved in the heterogeneity of hepatocytes. (biomedcentral.com)
  • A liver damage was observed in rats fed with high-fat diet via increase of liver lipid peroxidation and decreased hepatic antioxidant enzyme activities (superoxide dismutase, catalase and glutathione peroxidase). (biomedcentral.com)
  • BAF60a and BAF60c, two subunits of the SWI/SNF chromatin-remodeling complexes, are important for maintaining hepatic lipid metabolism. (biomedcentral.com)
  • The lower group of from six to twenty smaller hepatic veins come from the right lobe and the caudate lobe, are in contact with the hepatic tissue, and are valveless. (wikipedia.org)
  • Pathophysiologically, obstructive cholestasis increases biliary pressure that leads to rupture in cholangioles leading to the bile reflux back into hepatic tissues causing hepatotoxicity [ 5 ]. (bioscirep.org)
  • 5 ] in which LCA precipitates in both hepatic and biliary tissues causing obstructive cholestasis and initiates the inflammatory cycle. (bioscirep.org)
  • Treatment with ginseng extract decreased hepatic fat deposition and lowered hepatic reticular fiber accumulation compared with the CCl 4 group. (biomedcentral.com)
  • Consequently, these conditions lead to bile acid accumulation in hepatic tissues causing hepatotoxicity [ 3 , 4 ]. (bioscirep.org)
  • Similarly, LCA toxicity significantly down-regulated hepatic mRNA expression of constitutive androstane receptor, OATP4 , and farnesoid x receptor genes. (bioscirep.org)
  • Moreover, LCA causes down-regulation of hepatic mRNA expressions of a set of genes that are responsible for ATP binding cassette and anions permeability as ATP-binding cassette sub-family G member 8, organic anion-transporting polypeptide, and multidrug resistance-associated protein 2 genes that were ameliorated by artemisinin administration. (bioscirep.org)
  • Little is known about the effects on the liver induced by lipids and also few studies are focused on the effect of foods rich in TFAs on hepatic functions and oxidative stress. (biomedcentral.com)