The bonelike rigid connective tissue covering the root of a tooth from the cementoenamel junction to the apex and lining the apex of the root canal, also assisting in tooth support by serving as attachment structures for the periodontal ligament. (Jablonski, Dictionary of Dentistry, 1992)
The proteins that are part of the dental enamel matrix.
The part of a tooth from the neck to the apex, embedded in the alveolar process and covered with cementum. A root may be single or divided into several branches, usually identified by their relative position, e.g., lingual root or buccal root. Single-rooted teeth include mandibular first and second premolars and the maxillary second premolar teeth. The maxillary first premolar has two roots in most cases. Maxillary molars have three roots. (Jablonski, Dictionary of Dentistry, 1992, p690)
The formation of DENTAL CEMENTUM, a bone-like material that covers the root of the tooth.
A hard thin translucent layer of calcified substance which envelops and protects the dentin of the crown of the tooth. It is the hardest substance in the body and is almost entirely composed of calcium salts. Under the microscope, it is composed of thin rods (enamel prisms) held together by cementing substance, and surrounded by an enamel sheath. (From Jablonski, Dictionary of Dentistry, 1992, p286)
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
The fibrous CONNECTIVE TISSUE surrounding the TOOTH ROOT, separating it from and attaching it to the alveolar bone (ALVEOLAR PROCESS).
The structures surrounding and supporting the tooth. Periodontium includes the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.
Shiny, flexible bands of fibrous tissue connecting together articular extremities of bones. They are pliant, tough, and inextensile.
A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.
The process of TOOTH formation. It is divided into several stages including: the dental lamina stage, the bud stage, the cap stage, and the bell stage. Odontogenesis includes the production of tooth enamel (AMELOGENESIS), dentin (DENTINOGENESIS), and dental cementum (CEMENTOGENESIS).
A publication issued at stated, more or less regular, intervals.
An abnormality in the direction of a TOOTH ERUPTION.
One of a set of bone-like structures in the mouth used for biting and chewing.
An abnormal opening or fissure between two adjacent teeth.
The collective tissues from which an entire tooth is formed, including the DENTAL SAC; ENAMEL ORGAN; and DENTAL PAPILLA. (From Jablonski, Dictionary of Dentistry, 1992)
The largest and strongest bone of the FACE constituting the lower jaw. It supports the lower teeth.
The processes occurring in early development that direct morphogenesis. They specify the body plan ensuring that cells will proceed to differentiate, grow, and diversify in size and shape at the correct relative positions. Included are axial patterning, segmentation, compartment specification, limb position, organ boundary patterning, blood vessel patterning, etc.
The teeth collectively in the dental arch. Dentition ordinarily refers to the natural teeth in position in their alveoli. Dentition referring to the deciduous teeth is DENTITION, PRIMARY; to the permanent teeth, DENTITION, PERMANENT. (From Jablonski, Dictionary of Dentistry, 1992)
A major dental enamel-forming protein found in mammals. In humans the protein is encoded by GENES found on both the X CHROMOSOME and the Y CHROMOSOME.
Calcium salts of phosphoric acid. These compounds are frequently used as calcium supplements.
A spectroscopic technique in which a range of wavelengths is presented simultaneously with an interferometer and the spectrum is mathematically derived from the pattern thus obtained.
The elaboration of dental enamel by ameloblasts, beginning with its participation in the formation of the dentino-enamel junction to the production of the matrix for the enamel prisms and interprismatic substance. (Jablonski, Dictionary of Dentistry, 1992).
A clinically and genetically heterogeneous group of hereditary conditions characterized by malformed DENTAL ENAMEL, usually involving DENTAL ENAMEL HYPOPLASIA and/or TOOTH HYPOMINERALIZATION.
Group composed of associates of same species, approximately the same age, and usually of similar rank or social status.
A form of interactive entertainment in which the player controls electronically generated images that appear on a video display screen. This includes video games played in the home on special machines or home computers, and those played in arcades.
Recording of visual and sometimes sound signals on magnetic tape.
A quantitative measure of the frequency on average with which articles in a journal have been cited in a given period of time.
The evaluation by experts of the quality and pertinence of research or research proposals of other experts in the same field. Peer review is used by editors in deciding which submissions warrant publication, by granting agencies to determine which proposals should be funded, and by academic institutions in tenure decisions.
An organized procedure carried out by a select committee of professionals in evaluating the performance of other professionals in meeting the standards of their specialty. Review by peers is used by editors in the evaluation of articles and other papers submitted for publication. Peer review is used also in the evaluation of grant applications. It is applied also in evaluating the quality of health care provided to patients.

The root surface in human teeth: a microradiographic study. (1/33)

In an attempt to clarify the nature of the human cemento-dentinal junction, ground sections of incompletely formed and fully formed extracted teeth were prepared and their histology compared with their microradiographic appearances. The results showed that incompletely formed teeth possess distinctive surface layers outside the granular layer of Tomes. The evidence indicates that these layers are of dentinal origin; their presence during development supports previous explanations by the author of the hyaline layer of Hopewell-Smith and of so-called intermediate cementum. The results also indicate that the granular layer of Tomes does not represent the outer limit of root dentine. The relationship of these surface layers to the definitive cementum which is present in fully formed teeth was studied in both young and older patients. From the results it was concluded that cementum formation begins in the more apical region of the teeth at a time when root formation is well advanced, and that it spreads towards the crown rather than in the generally accepted reverse direction.  (+info)

On the configuration of incremental lines in human dentine as revealed by tetracycline labelling. (2/33)

The pattern of tetracycline labelling in dentine was investigated in ground sections of human teeth under visible and ultraviolet light. The tetracycline lines presented different appearances near the enamel-junction region, near the dentine-cementum junction, in the mantle dentine, and in the circumpulpal dentine, depending on whether the mineralization front was linear, globular or linear-globular.  (+info)

The developmental biology of cementum. (3/33)

In conclusion, we have reviewed an extensive literature on early cementogenesis and performed a detailed morphological and molecular analysis to illustrate and verify key issues in the current debate about epithelial and mesenchymal contributions to root cementum. We have demonstrated that prior to cementogenesis, Hertwig's epithelial root sheath disintegrates and dental follicle cells penetrate the epithelial layer to invade the root surface. Our studies confirmed that HERS became disrupted or disintegrated prior to cementum deposition. We visualized how mesenchymal cells from the dental follicle penetrated the HERS bilayer and deposited initial cementum, while immediately adjacent epithelial cells were separated from the root surface by a basal lamina and did not secrete any cementum. Human specimen from the Gottlieb collection indicated that HERS was removed from the root surface prior to cementum deposition. Our in situ hybridization and immolocalization data revealed that both amelogenin mRNAs and enamel proteins were restricted to the crown enamel and were absent from the root surface and from the cervical-most ameloblasts adjacent to the root margin. On Western blots, cementum protein extracts did not cross-react with amelogenin antibodies. Our studies in conjunction with our literature review together confirmed the classical theory of cementum as a dental follicle derived connective tissue that forms subsequent to HERS disintegration.  (+info)

Lesions related to the formation of bone, cartilage or cementum arising in the oral area: a statistical study and review of the literature. (4/33)

This report contains a statistical review of 559 cases of lesions forming hard tissues that were diagnosed by the departments of Clinical Pathophysiology and of Pathology at Tokyo Dental College from 1966 to 2001. Sixteen kinds of lesions which were related to the formation of bone, cartilage or cementum were analysed: osteoma, osteo-chondroma, chondroma, osteoid osteoma, osteoblastoma, ossifying fibroma, cemento-ossifying fibroma, cementifying fibroma, so-called cementoma, cementoblastoma, gigantiform cementoma, periapical cemental dysplasia, osteosarcoma, chondrosarcoma, fibro-osseous lesion, and fibrous dysplasia of bone. The most common lesion was osteoma (203 cases). There is a marked tendency for this condition to occur in females (201 males cases and 358 female cases). The patients' ages ranged from 3 to 84 years, and the mean was 40.1 years old. Lesions with hard tissue formation were observed most frequently in the third decade and in the mandibular molar region.  (+info)

Cementum and periodontal wound healing and regeneration. (5/33)

The extracellular matrix (ECM) of cementum resembles other mineralized tissues in composition; however, its physiology is unique, and it contains molecules that have not been detected in other tissues. Cementum components influence the activities of periodontal cells, and they manifest selectivity toward some periodontal cell types over others. In light of emerging evidence that the ECM determines how cells respond to environmental stimuli, we hypothesize that the local environment of the cementum matrix plays a pivotal role in maintaining the homeostasis of cementum under healthy conditions. The structural integrity and biochemical composition of the cementum matrix are severely compromised in periodontal disease, and the provisional matrix generated during periodontal healing is different from that of cementum. We propose that, for new cementum and attachment formation during periodontal regeneration, the local environment must be conducive for the recruitment and function of cementum-forming cells, and that the wound matrix is favorable for repair rather than regeneration. How cementum components may regulate and participate in cementum regeneration, possible new regenerative therapies using these principles, and models of cementoblastic cells are discussed.  (+info)

Gene therapy of bone morphogenetic protein for periodontal tissue engineering. (6/33)

BACKGROUND: The reconstruction of lost periodontal support including bone, ligament, and cementum is a major goal of therapy. Bone morphogenetic proteins (BMPs) have shown much potential in the regeneration of the periodontium. Limitations of BMP administration to periodontal lesions include need for high-dose bolus delivery, BMP transient biological activity, and low bioavailability of factors at the wound site. Gene transfer offers promise as an alternative treatment strategy to deliver BMPs to periodontal tissues. METHODS: This study utilized ex vivo BMP-7 gene transfer to stimulate tissue engineering of alveolar bone wounds. Syngeneic dermal fibroblasts (SDFs) were transduced ex vivo with adenoviruses encoding either green fluorescent protein (Ad-GFP or control virus), BMP-7 (Ad-BMP-7), or an antagonist of BMP bioactivity, noggin (Ad-noggin). Transduced cells were seeded onto gelatin carriers and then transplanted to large mandibular alveolar bone defects in a rat wound repair model. RESULTS: Ad-noggin treatment tended to inhibit osteogenesis as compared to the control-treated and Ad-BMP-7-treated specimens. The osseous lesions treated by Ad-BMP-7 gene delivery demonstrated rapid chrondrogenesis, with subsequent osteogenesis, cementogenesis and predictable bridging of the periodontal bone defects. CONCLUSION: These results demonstrate the first successful evidence of periodontal tissue engineering using ex vivo gene transfer of BMPs and offers a new approach for repairing periodontal defects.  (+info)

Cementoblast delivery for periodontal tissue engineering. (7/33)

BACKGROUND: Predictable periodontal regeneration following periodontal disease is a major goal of therapy. The objective of this proof of concept investigation was to evaluate the ability of cementoblasts and dental follicle cells to promote periodontal regeneration in a rodent periodontal fenestration model. METHODS: The buccal aspect of the distal root of the first mandibular molar was denuded of its periodontal ligament (PDL), cementum, and superficial dentin through a bony window created bilaterally in 12 athymic rats. Treated defects were divided into three groups: 1) carrier alone (PLGA polymer sponges), 2) carrier + follicle cells, and 3) carrier + cementoblasts. Cultured murine primary follicle cells and immortalized cementoblasts were delivered to the defects via biodegradable PLGA polymer sponges, and mandibulae were retrieved 3 weeks and 6 weeks post-surgery for histological evaluation. In situ hybridization, for gene expression of bone sialoprotein (BSP) and osteocalcin (OCN), and histomorphometric analysis were further done on 3-week specimens. RESULTS: Three weeks after surgery, histology of defects treated with carrier alone indicated PLGA particles, fibrous tissue, and newly formed bone scattered within the defect area. Defects treated with carrier + follicle cells had a similar appearance, but with less formation of bone. In contrast, in defects treated with carrier + cementoblasts, mineralized tissues were noted at the healing site with extension toward the root surface, PDL region, and laterally beyond the buccal plate envelope of bone. No PDL-bone fibrous attachment was observed in any of the groups at this point. In situ hybridization showed that the mineralized tissue formed by cementoblasts gave strong signals for both BSP and OCN genes, confirming its nature as cementum or bone. The changes noted at 3 weeks were also observed at 6 weeks. Cementoblast-treated and carrier alone-treated defects exhibited complete bone bridging and PDL formation, whereas follicle cell-treated defects showed minimal evidence of osteogenesis. No new cementum was formed along the root surface in the above two groups. Cementoblast-treated defects were filled with trabeculated mineralized tissue similar to, but more mature, than that seen at 3 weeks. Furthermore, the PDL region was maintained with well-organized collagen fibers connecting the adjacent bone to a thin layer of cementum-like tissue observed on the root surface. Neoplastic changes were observed at the superficial portions of the implants in two of the 6-week cementoblast-treated specimens, possibly due in part to the SV40-transformed nature of the implanted cell line. CONCLUSIONS: This pilot study demonstrates that cementoblasts have a marked ability to induce mineralization in periodontal wounds when delivered via polymer sponges, while implanted dental follicle cells seem to inhibit periodontal healing. These results confirm the selective behaviors of different cell types in vivo and support the role of cementoblasts as a tool to better understand periodontal regeneration and cementogen-  (+info)

Effect of sustained gene delivery of platelet-derived growth factor or its antagonist (PDGF-1308) on tissue-engineered cementum. (8/33)

BACKGROUND: Cementum, a mineralized tissue lining the tooth root surface, is destroyed during the inflammatory process of periodontitis. Restoration of functional cementum is considered a criterion for successful regeneration of periodontal tissues, including formation of periodontal ligament, cementum, and alveolar bone. Short-term administration of platelet-derived growth factor (PDGF) has been shown to partially regenerate periodontal structures. Nonetheless, the role of PDGF in cementogenesis is not well understood. The aim of the present study was to determine the effect of sustained PDGF gene transfer on cementum formation in an ex vivo ectopic biomineralization model. METHODS: Osteocalcin (OC) promoter-driven SV40 transgenic mice were used to obtain immortalized cementoblasts (OCCM). The OCCM cells were transduced with adenoviruses (Ad) encoding either PDGF-A, an antagonist of PDGF signaling (PDGF-1308), a control virus (green fluorescent protein, GFP), or no treatment (NT). The transduced cells were incorporated into polymer scaffolds and implanted subcutaneously into severe combined immunodeficient (SCID) mice. The implants were harvested at 3 and 6 weeks for histomorphometric analysis of the newly formed mineralized tissues. Northern blot analysis was performed to determine the expression levels of mineral-associated genes including bone sialoprotein (BSP), OC, and osteopontin (OPN) in the cell-implant specimens at 3 and 6 weeks. RESULTS: The results indicated mineralization was significantly reduced in both the Ad/PDGF-A and Ad/PDGF-1308 treated specimens when compared to the NT or Ad/GFP groups at 3 and 6 weeks (P<0.01). In addition, the size of the implants treated with Ad/PDGF-A and Ad/PDGF-1308 was significantly reduced compared to implants from Ad/GFP and NT groups at 3 weeks (P<0.05). At 6 weeks, the size of implants and mineral formation increased in NT, Ad/GFP, and Ad/PDGF-A groups, while the Ad/PDGF-1308 treated implants continued to decrease in size and mineral formation (P<0.01). Northern blot analysis revealed that in the Ad/PDGF-A treated implants OPN was increased, whereas OC gene expression was downregulated at 3 weeks. In the Ad/PDGF-1308 treated implants, BSP, OC, and OPN were all downregulated at 3 weeks. At 3 weeks, the Ad/PDGF-A treated implants contained significantly higher multinucleated giant cell (MNGC) density compared to NT, Ad/GFP, and Ad/PDGF-1308 specimens. The MNGC density in NT, Ad/GFP, and Ad/PDGF-A treated groups reduced over time, while the Ad/PDGF-1308 transduced implants continued to exhibit significantly higher MNGC density compared with the other treatment groups at 6 weeks. CONCLUSIONS: The results showed that continuous exposure to PDGF-A had an inhibitory effect on cementogenesis, possibly via the upregulation of OPN and subsequent enhancement of MNGCs at 3 weeks. On the other hand, Ad/PDGF-1308 inhibited mineralization of tissue-engineered cementum possibly due to the observed downregulation of BSP and OC and a persistence of stimulation of MNGCs. These findings suggest that continuous exogenous delivery of PDGF-A may delay mineral formation induced by cementoblasts, while PDGF is clearly required for mineral neogenesis.  (+info)

Υπόβαθρο: Η παγκόσμια οικονομική κρίση επηρεάζει τις πολιτικές υγείας παγκοσμίως, ενώ το Ευρωπαϊκό πλαίσιο πολιτικής «Υγεία 2020» επιδιώκει τη δημιουργία βιώσιμων, ισότιμα προσβάσιμων, υψηλής ποιότητας, ασθενοκεντρικών ...
Purpose/Aim: Cementogenesis is a critical step in periodontal tissue regeneration given the essential role of cementum in anchoring teeth to the alveolar bone. This study is designed to achieve integrated cementum formation on the root surfaces of human teeth using growth factor-releasing scaffolds with periodontal ligament stem/progenitor cells (PDLSCs). Materials and methods: Human PDLSCs were sorted by CD146 expression, and characterized using CFU-F assay and induced multi-lineage differentiation. Polycaprolactone scaffolds were fabricated using 3D printing, embedded with poly(lactic-co-glycolic acids) (PLGA) microspheres encapsulating connective tissue growth factor (CTGF), bone morphogenetic protein-2 (BMP-2), or bone morphogenetic protein-7 (BMP-7). After removing cementum on…. ...
Aim: Keratin preparations have been shown to have bioactive effects on various cells including osteoblasts and neurons and offer the potential as a biomaterial in tissue regeneration. The aim of this study was to assess the in vitro effect of keratin preparations on the viability and proliferation of cementoblast OCCM-30 and fibroblast L929 cells and on the mineralisation capability of the OCCM-30 cells.. Method: Cementoblast OCCM-30 cells were grown in Dulbeccos modified Eagles medium (DMEM) with 10% Fetal bovine serum (FBS) and 1% antibiotic-antimycotic. The fibroblast L929 cells were grown in minimum essential media (MEM) with 10% FBS and 1% antibiotic-antimycotic. The cells of L929 and OCCM-30 were assessed for viability in growth media supplemented with 10 mg/ml, 1 mg/ml and 0.1 mg/ml of keratin with a LIVE/DEAD assay™ Kit using confocal laser scanning microscope. Cell proliferation was tested with similar keratin concentrations using an alamarBlue® proliferation assay at 0, 24, 48 and ...
The process of TOOTH formation. It is divided into several stages including: the dental lamina stage, the bud stage, the cap stage, and the bell stage. Odontogenesis includes the production of tooth enamel (AMELOGENESIS), dentin (DENTINOGENESIS), and dental cementum (CEMENTOGENESIS ...
Title:Role of the Epithelial Cell Rests of Malassez in Periodontal Homeostasis and Regeneration - A Review. VOLUME: 10 ISSUE: 5. Author(s):Zhenhua Yang, Yanjiao Li, Xiaojie Ma, Lin Shen, Zhihe Zhao and Fang Jin. Affiliation:145 West Changle Road, Xian, Shaanxi 710032, PR China;. Keywords:Hertwigs epithelial root sheath, epithelial cell rests Malassez, periodontium development, periodontal regeneration, cementogenesis, stem cells.. Abstract:Predictable and complete periodontal regeneration following periodontitis has been the ultimate goal of periodontal treatment. It has been recognized that Hertwigs epithelial root sheath (HERS) cells play a crucial role in cementogenesis and root formation. As the descendants of HERS and unique odontogenic epithelium in the adult periodontium, epithelial cell rests of Malassez (ERM) have long been considered as quiescent epithelial remnants devoid of structure and function. Here we will present an overview of our present understanding and putative functions ...
BSP is multifunctional, affecting cell attachment and signaling through an RGD integrin-binding region, and acting as a positive regulator for mineral precipitation by nucleating hydroxyapatite crystals. BSP is present in cementum, the hard tissue covering the tooth root that anchors periodontal ligament PDL attachment.. Results collected here suggest that BSP plays a non-redundant role in acellular cementum formation, likely involved in initiating mineralization on the root surface. Through its importance to cementum integrity, BSP is essential for periodontal function. Keywords: bone sialoprotein, cementum, periodontal ligament, bone, alkaline phosphatase, extracellular matrix Introduction Bone sialoprotein BSP, or integrin binding sialoprotein is an extracellular matrix protein in the Small Integrin Binding Ligand N-linked Glycoprotein SIBLING family, associated with mineralized tissues of the skeleton and dentition Ganss et al.. The ability of BSP to act as a positive regulator of ...
The speed of degradation of Syn Oss = Rate of bone formation Degrades fully within 6 - 12 months, depending upon regeneration dynamics of the patient.. Syn Oss is indicated for filling of mostly non-stressed, multiple bone defects of the skeleton. The augmentation site should be free of inflamation, soft tissue, granulation tissue & infection. Indications include : Post extraction ridge ...
Background. Stem cells have contributed to the development of tissue-engineered-based regenerative periodontal therapies. In order to find the best stem cell sources for such therapies, the biologic properties of stem cells isolated from periodontal ligaments (PDL) of deciduous (DePDLSC) and permanent (PePDLSC) teeth were comparatively evaluated. Methods. PDL stem cells were isolated from six sound fully erupted premolars and six deciduous canines of healthy subjects. In vitro biologic characteristics such as colony formation, viability, stem cell marker identification and osteogenic differentiation (using alkaline phosphatase analysis and Alizarin red staining) were comparatively assessed using one-way ANOVA and post hoc Tukey tests using SPSS 13 ...
Meanwhile, since he was sedated for the ultrasound, the vets took a closer look at Fitz teeth. His gums were receding so much that the roots of two teeth were almost entirely exposed. One had a huge tartar cap on it that was so hard it took a Dremel to drill through it and break it apart. (Weve since heard this abnormal tartar buildup called a cementoblast.) As the vet drilled into the cementoblast, the bit went right through what should have been tooth behind it and into dead bone. The infection in the tooth had moved into the bone and caused some decay. A second infected incisor was also removed, but there was no bone involvement in relation to that one. That left one more incisor with most of the root exposed, but it still seemed to be firmly in place and not infected, so it was left alone for the time being ...
Molecules involved in periodontal regeneration, Cytokines, Growth factors, Adhesion molecules, Fibroblast growth factor-1 and -2, Bone morphogenetic proteins, Insulin-like growth factor-I and II, Platelet-derived growth factor.
Fu, J.-H.,Wang, H.-L. (2013-04-05). Clinical Correlate: Periodontal Regeneration. Mineralized Tissues in Oral and Craniofacial Science: Biological Principles and Clinical Correlates : 201-205. [email protected] Repository. https://doi.org/10.1002/9781118704868.ch23 ...
TY - JOUR. T1 - Effect of platelet-rich plasma on the healing of intrabony defects treated with beta tricalcium phosphate and expanded polytetrafluoroethylene membranes. AU - Döri, Ferenc. AU - Huszár, Tamás. AU - Nikolidakis, Dimitris. AU - Tihanyi, Dora. AU - Horváth, Attila. AU - Arweiler, Nicole B.. AU - Gera, I.. AU - Sculean, Anton. PY - 2008/4. Y1 - 2008/4. N2 - Background: Regenerative periodontal therapy using platelet-rich plasma (PRP) and different types of bone substitutes with or without guided tissue regeneration (GTR) has been proposed as a modality to enhance the outcome of regenerative surgery. However, there are limited data from controlled clinical studies evaluating the effect of PRP on the healing of deep intrabony defects treated with a combination of bone substitutes and GTR. The aim of this study was to clinically evaluate the effect of PRP on the healing of deep intrabony defects treated with beta tricalcium phosphate (β-TCP) and GTR by means of a non-bioresorbable ...
There are three hard tissues that comprise human teeth: enamel, dentin and cementum. The majority of the tooth structure is formed from dentin, and the enamel serves as the superficial layer of the crown while the cementum serves to cover the root. In the mid-1990s, however, it was discovered that a very thin layer of enamel actually exists between the dentin and cementum on the roots of adult human teeth. This led researchers to conclude that enamel matrix proteins (or EMPs) laid down by Hertwigs epithelial root sheath serve as precursors to acellular cementum during its formation, known as cementogenesis.[1] The presence of acellular cementum acts to signal the development of periodontal ligament fibers, followed by new alveolar bone, thus leading to the formation of the tissues of the periodontium.[2]. ...
Regenics bone regeneration synthetic materials regenics bone regeneration help regeneration of bone synthetic materials materials regenics synthetic
Title:Recent Advances in Cell Sheet Technology for Periodontal Regeneration. VOLUME: 9 ISSUE: 3. Author(s):Jing Wang, Rui Zhang, Yun Shen, Chenyuan Xu, Shengcai Qi, Liyan Lu, Raorao Wang and Yuanzhi Xu. Affiliation:Department of Stomatology, Shanghai Tenth Peoples Hospital, Tongji University School of Medicine, No. 301, Middle Yanchang Road, Shanghai 200072, P.R. China.. Keywords:Application, cell sheet technology, co-culture, micro-printing, periodontal regeneration, tissue engineering.. Abstract:Tissue engineering has yielded several successes in early clinical trials of regenerative medicine with grafting therapeutic cells seeded into biodegradable scaffolds. However this conventional cell delivery method has limited the fields progress. In recent decades, we have developed a novel cell transferring method, cell sheet technology that allows for controlled attachment and detachment of cells via simple temperature variations of a surface-intelligent temperatureresponsive polymer:poly ...
0033] In a particular embodiment of the present invention, the concentration of the growth and differentiation factors incorporated in cell-guiding scaffolds can be adjusted according to the release kinetics influenced by the scaffold material, the presence of the intermediate binding agent (protein, glycoprotein, glycosaminoglycan, polysaccharide) and the type of the binding (covalent crosslinking or otherwise). According to a specific aspect of the embodiment, basic fibroblast growth factor (bFGF) concentration varies in the range of 1 μg/ml-1000 μg/ml, and more preferably between 5 μg/ml-500 μg/ml, and still more preferably between 10 μg/ml-300 μg/ml. In a multicenter randomized double-blinded clinical study, the bFGF application to periodontal defects at concentration ranging between 300 μg/ml-3000 μg/ml resulted with a significant attachment gain and 2-fold bone height gain after 36 months postoperatively (Kitamura et al. PLoS ONE. 2008; 3(7):e2611.) According to another aspect of ...
The cells of cementum are the entrapped cementoblasts, the cementocytes. Each cementocyte lies in its lacuna, similar to the pattern noted in bone. These lacunae also have canaliculi or canals. Unlike those in bone, however, these canals in cementum do not contain nerves, nor do they radiate outward. Instead, the canals are oriented toward the periodontal ligament and contain cementocytic processes that exist to diffuse nutrients from the ligament because it is vascularized. After the apposition of cementum in layers, the cementoblasts that do not become entrapped in cementum line up along the cemental surface along the length of the outer covering of the periodontal ligament. These cementoblasts can form subsequent layers of cementum if the tooth is injured. Sharpey fibers are part of the principal collagenous fibers of the periodontal ligament embedded in the cementum and alveolar bone to attach the tooth to the alveolus.[2] ...
Periodontal regeneration - true regeneration of the attachment apparatus (new cementum, new periodontal ligament, and new alveolar bone) on a previously diseased root surface when used specifically in the LANAP® Protocol. 510(k) ...
Immunohistochemical Localization of Osteopontin - A Comparative Study on Periodontally Healthy and Diseased Tooth Root Surface, Julie Toby Thomas, Toby
Principal Investigator:TANAKA SAORI, Project Period (FY):2013-04-01 - 2016-03-31, Research Category:Grant-in-Aid for Scientific Research (C), Section:一般, Research Field:Conservative dentistry
Hyaluronic acid (HA) is a natural-non sulphated high molecular weight glycosaminoglycan that forms a critical component of the extracellular matrix and contributes significantly to tissue hydrodynamics, cell migration and proliferation. The use of HA
Professor - Division of Periodontics - FOP-UNICAMP - Citado por 9.060 - periodontal research - randomized clinical trials - periodontal regeneration
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1PC3: Crystal structure of M tuberculosis ABC phosphate transport receptor: specificity and charge compensation dominated by ion-dipole interactions.
Looking for online definition of tip of tooth root in the Medical Dictionary? tip of tooth root explanation free. What is tip of tooth root? Meaning of tip of tooth root medical term. What does tip of tooth root mean?
The use of guided tissue regeneration procedures has intensified the need to determine the types and quantity of tissues formed in healing. Regeneration is differentiated from new attachment in one basic, but very important manner: alveolar bone formation with new inserted periodontal fibers in new cementum is a prerequisite for the regeneration of periodontium (4-6). Areas of new cementum deposition without adjacent bone, and vice-versa, and areas of ankylosis, for example, do not satisfy the criteria for regeneration (7). Furthermore, recent advances in the understanding of functions and mechanisms of action of growth factors to regulate the healing process have provided evidence that these proteins may serve as therapeutic agents to enhance the healing of periodontal wounds (8-11). Sigurdsson et al. (12) found a significant enhancement in periodontal regeneration using the rhBMP-2 in dog models. They described limited root resorption and ankylosis generally limited immediately apical to the ...
Every single member from our large efficiency profits team values customers requirements and organization communication for Tricalcium Phosphate Hs Code , Tricalcium Phosphate Powder , tricalcium phosphate hs code , We believe that good business relationships will lead to mutual benefits and improvement for both parties. We have established long-term and successful cooperative relationships with many customers through their confidence in our customized services and integrity in doing business. We also enjoy a high reputation through our good performance. Better performance will be expected as our principle of integrity. Devotion and Steadiness will remain as ever ...
The case shown here is of a 46 year-old female patient diagnosed with a severe generalised Chronic Periodontitis. The x-rays revealed the presence of several angular bony defects, known to progress quickly if left untreated, leading to tooth loss.. ...
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Normal Periodontium and its components including gingiva, periodontal ligament, cementum, alveolar bone. Formation, classification and functions of these components.
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Periodontal regeneration is now FDA-approved -- for the first time ever. Your periodontist in Florham Park is excited to share the news about the treatment.
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The ACP Education Foundation is proud to announce the recipient of the 2015 GSK Prosthodontist Innovator Award.. Dr. Alireza Moshaverinia is a tenure-track assistant professor at the UCLA School of Dentistry. His research, titled Novel Multifunctional Polymeric Membrane for Periodontal Tissue Engineering, aims to develop a novel bioactive smart membrane for periodontal tissue regeneration and promising treatment approach for maxillofacial and skeletal defects.. More information on this educational grant:. ...
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Human periodontal ligament stem cells (hPDLSCs) are best seed cells for periodontal regeneration. A larger understanding of the dynamic protein profiles throughout osteogenic differentiation contributed to the advance of periodontal regeneration tissue engineering. Tandem Mass Tag quantitative proteomics was utilized to disclose the temporal protein expression sample throughout osteogenic differentiation of hPDLSCs on days.... ...
Principal Investigator:Toyoda Kyosuke, Project Period (FY):2015-08-28 - 2017-03-31, Research Category:Grant-in-Aid for Research Activity start-up, Research Field:Periodontology
The report generally describes tricalcium phosphate, examines its uses, production methods, patents. Tricalcium phosphate market situation is overviewed;
Human periodontal ligament stem cells (hPDLSCs) are best seed cells for periodontal regeneration. A larger understanding of the dynamic protein profiles throughout osteogenic differentiation contributed to the advance of periodontal regeneration tissue engineering. Tandem Mass Tag quantitative proteomics was utilized to disclose the temporal protein expression sample throughout osteogenic differentiation of hPDLSCs on days.... ...
A high purity α-tricalcium phosphate ceramic having a superior biocompatibility for use mainly as a bone filler, is produced by shaping a powder material formed by a wet method, followed by sintering it and then cooling at a predetermined rate.
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TY - JOUR. T1 - Reaction of bone to tricalcium phosphate ceramic pellets. AU - Cutright, Duane E.. AU - Bhaskar, Surindar N.. AU - Brady, John M.. AU - Getter, Lee. AU - Posey, William R.. PY - 1972/1/1. Y1 - 1972/1/1. N2 - This study indicates that tricalcium phosphate is well accepted by the tissue and may actually contribute mineral salts for the formation of bone at the site as the ceramic is broken down into granules.. AB - This study indicates that tricalcium phosphate is well accepted by the tissue and may actually contribute mineral salts for the formation of bone at the site as the ceramic is broken down into granules.. UR - http://www.scopus.com/inward/record.url?scp=0015337449&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0015337449&partnerID=8YFLogxK. U2 - 10.1016/0030-4220(72)90457-4. DO - 10.1016/0030-4220(72)90457-4. M3 - Article. C2 - 4502161. AN - SCOPUS:0015337449. VL - 33. SP - 850. EP - 856. JO - Oral Surgery, Oral Medicine, Oral Pathology and Oral ...
Detail of the period when the root sheath cells (blue) secrete enamel matrix proteins. Following formation of the protein matrix on the surface of the mineralizing dentin, cementoblasts (Red) start producing cementum (Light blue) which anchors collagen fibers.. The Next Generation. In the mid 1980s, a revolutionary breakthrough in the basic biology of tooth development took place at the Karolinska Institutes department of Oral Pathology in Stockholm. The discovery revealed a native complex of enamel matrix proteins and the key if not crucial , role they play in the development of tooth-supporting tissues. These enamel related proteins mediate the formation of acellular cementum on the root of the developing tooth, providing a foundation for all of the necessary tissues associated with a functional periodontal attachment.. This groundbreaking discovery has fueled the development of a new generation in periodontal therapy, and makes the recreation of lost tooth support an attainable goal in the ...
Sintering Behavior and Mechanical Properties of Magnesium/β-Tricalcium Phosphate Composites Sintered by Spark Plasma SinteringSintering Behavior and Mechanical Properties of Magnesium/β-Tricalcium Phosphate Composites Sintered by Spark Plasma Sintering ...
The good news is that cementum can repair itself. Cementoblasts - cells in your tooth root - make cementum continuously throughout your life as the old cementum ages and thins. This way your teeth stay firmly embedded in your jawbone.. Your goal is to support this natural repair process, to neatly close off your exposed dentinal tubules with cementum.. Cementum is about 50% hydroxylapatite. Tooth enamel is 90% hydroxylapatite, and bone is 70%. Hydroxylapatite is a calcium phosphate mineral, also known as the bone mineral.. Acid food and drinks dissolve hydroxylapatite, and hence cementum. Enamel begins to demineralize at a pH of 5.5.. Yet another reason to eat a high-alkaline diet! When raw fooders eat too much acidic citrus, it dissolves their tooth enamel. They get sensitive teeth. Watch those oranges and lemons. Juice them, or rinse your mouth after eating.. The other 50% of cementum (the part that isnt calcified hydroxylapatite) is mainly collagen and protein polysaccharides (compounds of ...
Platelet concentrate is nothing but a centrifuged blood with only platelets and fibrin in maximum amount and less or very few leucocytes at the bottom. Other
Research Report on EMEA (Europe, Middle East and Africa) Tricalcium Phosphate (TCP) Market Report 2017. The Report includes market price, demand, trends, size, Share, Growth, Forecast, Analysis & Overview.
Esthetics and Periodontium Online publication: December 24, 2009 Introductory pages (p. 1-5) Contents (p. 6-7) Scientific Editors note (p. 8) Full t...
In this study, DNA analyses were employed to verify the identity of six morphologically similar species that occur in the coastal waters of Taiwan: the black seabream complex (Acanthopagrus latus, Acanthopagrus schlegelii, Acanthopagrus sivicolus, Acanthopagrus taiwanensis, Acanthopagrus chinshira and Acanthopagrus pacificus). Amplified fragment‐length polymorphism (AFLP) analyses clearly distinguished the same six species that are morphologically diagnosable based on subtle differences in scale counts and anal‐fin colouration. In contrast, mitochondrial DNA analyses based on cytochrome b gene sequences did not distinguish individuals of A. schlegelii and A. sivicolus, reflecting either historical introgression or recent speciation and incomplete sorting of their mitochondrial lineages. Phylogenetic relationships among these six north‐west Pacific Ocean species of Acanthopagrus analysed using AFLP data were consistent with scale rows above the lateral line (TRac), sperm ultrastructure and ...
Discovery of EMP's role in cementogenesis[edit]. There are three hard tissues that comprise human teeth: enamel, dentin and ... known as cementogenesis.[1] The presence of acellular cementum acts to signal the development of periodontal ligament fibers, ...
Cementogenesis • Cementum • Central giant cell granuloma • Central odontogenic fibroma • Central ossifying fibroma • Central ...
Main article: Cementogenesis. Cementum is secreted by cells called cementoblasts within the root of the tooth and is thickest ...
Cementum formation is called cementogenesis and occurs late in the development of teeth. Cementoblasts are the cells ... responsible for cementogenesis. Two types of cementum form: cellular and acellular. Acellular cementum forms first. The ...
Cementum Cementogenesis Cementoblast Sankari Leena S, Ramakrishnan K (2011). "Benign cementoblastoma". Journal of Oral and ...
Complications of cementogenesis and proliferation of cementoblasts can be implicated; however, cementomas have only been linked ...
Cementum Cementogenesis Tooth development Cementoblastoma Enamel List of human cell types derived from the germ layers Ten ... and whose biological function is cementogenesis, which is the formation of cementum (hard tissue that covers the tooth root). ...
... but HERS may be involved in cementogenesis and the secreting of cementum, or that HERS-derived products might be related to ...
... cementogenesis MeSH G07.574.500.325.377.750.461 - dentinogenesis MeSH G07.574.500.325.520 - sex differentiation MeSH G07.574. ...
... is the formation of cementum, one of the three mineralized substances of a tooth. Cementum covers the roots of ... The cementoblasts then disperse to cover the root dentin area and undergo cementogenesis, laying down cementoid. During the ... For cementogenesis to begin, Hertwig epithelial root sheath (HERS) must fragment. HERS is a collar of epithelial cells derived ... This then stimulates the activation of cementoblasts to begin cementogenesis. The external shape of each root is fully ...
... is the degree of maturation of a child's bones. As a person grows from fetal life through childhood, puberty, and finishes growth as a young adult, the bones of the skeleton change in size and shape. These changes can be seen by x-ray. The "bone age" of a child is the average age at which children reach this stage of bone maturation. A child's current height and bone age can be used to predict adult height. For most people, their bone age is the same as their biological age but for some individuals, their bone age is a couple years older or younger. Those with advanced bone ages typically hit a growth spurt early on but stop growing early sooner while those with delayed bone ages hit their growth spurt later than normal. Kids who are below average height do not necessarily have a delayed bone age; in fact their bone age could actually be advanced which if left untreated, will stunt their growth. At birth, only the metaphyses of the "long bones" are present. The long bones are those that ...
Talk:Cementogenesis. *Talk:Cementum. *Talk:Center for Biofilm Engineering. *Talk:Central giant-cell granuloma ...
Cementogenesis is the formation of cementum, one of the three mineralized substances of a tooth. Cementum covers the roots of ... The cementoblasts then disperse to cover the root dentin area and undergo cementogenesis, laying down cementoid. During the ... For cementogenesis to begin, Hertwig epithelial root sheath (HERS) must fragment. HERS is a collar of epithelial cells derived ... This then stimulates the activation of cementoblasts to begin cementogenesis. The external shape of each root is fully ...
Several aspects of cementogenesis remain unclear, including differences between acellular cementum and cellular cementum, and ... The focus of this study was to define the roles of these phosphatases in cementogenesis. TNAP was associated with earliest ... Developmental expression of TNAP during molar root formation. Prior to onset of cementogenesis in first molars at (a, b) 4 dpn ... Developmental expression of NPP1 during molar root formation. (a, b) At 8 dpn, at the earliest initiation of cementogenesis, ...
Journal Article] Experimental Model for Cementogenesis using Dental Follicle2003. *. Author(s). K.Handa, M.Saito, A.Tsunoda, S. ... Transplantation study of the dental follicle provides a useful model for investigating molecular mechanisms of cementogenesis. ... Development of poiodontal regenerative medicine that based on molecular mechanism of cementogenesis.. Research Project ...
"Cementogenesis" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... This graph shows the total number of publications written about "Cementogenesis" by people in this website by year, and whether ... Below are the most recent publications written about "Cementogenesis" by people in Profiles. ... "Cementogenesis" was a major or minor topic of these publications. To see the data from this visualization as text, click here. ...
Discovery of EMPs role in cementogenesis[edit]. There are three hard tissues that comprise human teeth: enamel, dentin and ... known as cementogenesis.[1] The presence of acellular cementum acts to signal the development of periodontal ligament fibers, ...
Main article: Cementogenesis. Cementum is secreted by cells called cementoblasts within the root of the tooth and is thickest ...
... Connect Tissue Res ... localized to the cemental root surface at latter periods coincident with the initiation of root formation and cementogenesis. ... suggest that BSP and OPN are intimately involved in the sequence of cellular and molecular events accompanying cementogenesis. ...
Hertwigs Epithelial Root Sheath Fate during Initial Cellular Cementogenesis in Rat Molars. Files in This Item: A20_48_15006. ... To elucidate the fate of the epithelial root sheath during initial cellular cementogenesis, we examined developing maxillary ... Hertwigs Epithelial Root Sheath Fate during Initial Cellular Cementogenesis in Rat Molars. ... where initial cellular cementogenesis begins. After fragmentation of the epithelial sheath, many keratin-positive epithelial ...
Cementogenesis • Cementum • Central giant cell granuloma • Central odontogenic fibroma • Central ossifying fibroma • Central ...
... a few are embedded into the cementum during cementogenesis (N, indicated by arrow). Dental mesenchymal cells are detectable ...
Cementogenesis. the formation of cementum. Cementoid. the most recent uncalcified layer covering the surface of cementum. ...
7 Root Formation and Cementogenesis 8 Bone 9 Salivary Glands 10 Oral Somatosensory Systems 11 Muscle 12 Cartilage and ...
Intermittent parathyroid hormone promotes cementogenesis via ephrinB2-EPHB4 forward signaling. March 01, 2021 ...
... has been shown to have a role in the upregulation of osteopontin in cementogenesis via the MAPK pathway (Boabaid et al. 2004). ... a candidate signaling molecule during cementogenesis. J Periodontol 75, 1126-1136. *CrossRef , ...
Amelogenin Promotes Dentinogenesis And Cementogenesis Of Dental/periodontal Stem/progenitor Cells. J. GU1, M. CHEN1, T. SHEU2, ...
Several aspects of cementogenesis remain unclear, including differences between acellular cementum and cellular cementum, and ... "Counter-regulatory phosphatases TNAP and NPP1 temporally regulate tooth root cementogenesis". International Journal of Oral ...
2004). Leucine-rich amelogenin peptide: a candidate signaling molecule during cementogenesis. J. Periodontol. 75, 1126-1136. ...
Induction of cementogenesis and periodontal ligament regeneration by the bone morphogenetic proteins.- Control of bone mass by ...
2014). Counter-regulatory phosphatases TNAP and NPP1 temporally regulate tooth root cementogenesis. Int. J. Oral Sci. 7, 27-41 ...
Notably, simultaneous β-catenin knockout rescued ectopic cementogenesis caused by Bmpr1a knockout by inhibiting EMT; while ... this study provided the direct in vivo evidences for epithelia-originated cementogenesis through EMT. ... simultaneous Wnt1 over-expression advanced Bmpr1a knockout-induced ectopic cementogenesis by further promoting EMT. Conclusions ...
Nagaishi, The effect of various implant materials on cementogenesis, Nippon Shishubyo Gakkai Kaishi, 31(2):551-572 (1989).. ...
Hertwigs epithelial root sheath, enamel matrix proteins, and initiation of cementogenesis in porcine teeth BOSSHARDT DD ...
Leucine-rich amelogenin peptide: a candidate signaling molecule during cementogenesis. J Periodontol. 2004;75(8):1126-36. ...
Bone morphogenetic protein-2 stimulates cell recruitment and cementogenesis during early wound healing. J Clin Periodontol 2001 ...
Bone morphogenetic protein-2 stimulates cell recruitment and cementogenesis during early wound healing. J Clin Periodontol 2001 ...
PDL-derived cells (PDLCs) express both osteo/cementogenesis and teno/ligamentogenesis genes. However, an efficient method to ...
Copyright Get Revising 2018 all rights reserved. Get Revising is one of the trading names of The Student Room Group Ltd. Register Number: 04666380 (England and Wales), VAT No. 806 8067 22 Registered office: International House, Queens Road, Brighton, BN1 3XE ...
7 Root Formation and Cementogenesis 8 Bone 9 Salivary Glands 10 Oral Somatosensory Systems 11 Muscle 12 Cartilage and ...
1Histologic evaluation of cementogenesis on periodontitis-affected roots in humans (pp. 429-435). Middleton. Bowers ...
... collagen-producing cells that become entrapped in the extracellular matrix they excrete during cementogenesis. The canaliculi ...
  • Several aspects of cementogenesis remain unclear, including differences between acellular cementum and cellular cementum, and between cementum and bone. (nature.com)
  • Cementogenesis is the formation of cementum, one of the three mineralized substances of a tooth. (wikipedia.org)
  • This led researchers to conclude that enamel matrix proteins (or EMPs) laid down by Hertwig's epithelial root sheath serve as precursors to acellular cementum during its formation, known as cementogenesis . (wikipedia.org)
  • Odontogenesis includes the production of tooth enamel (AMELOGENESIS), dentin (DENTINOGENESIS), and dental cementum (CEMENTOGENESIS). (umassmed.edu)
  • We will isolate primary periodontal cell, from 2 week animals that have no cellular cementum related but acellular cementoblast precursors, and PDL and osteoblast cells, 2 month animals undergoing active cellular cementogenesis, PDL formation and osteogenesis, and 6 month animals in which cementogenesis is complete. (uthscsa.edu)
  • Bone sialoprotein and osteopontin are the two major non-collagenous proteins in cementum that appeared to have important roles in cementogenesis and regeneration. (imedpub.com)
  • Developmental factors directing cementogenesis remain poorly defined, hampering progress toward more effective therapies for cementum regeneration. (kedstroy.ru)
  • For cementum, cementogenesis is being studied and the attempts to cover the root dentin by neo-cementum are promising [12] . (scidoc.org)
  • Intermittent parathyroid hormone promotes cementogenesis via ephrinB2-EPHB4 forward signaling. (medscape.com)
  • During the periodontal regeneration process, periodontal ligament (PDL) cells play an important role in forming new attachments between these tissues as well as cementogenesis and osteogenesis. (nii.ac.jp)
  • By validation in vivo, we will determine a set of genes that is selectively expressed during cementogenesis and not osteogenesis. (uthscsa.edu)
  • Recently, Osterix (Osx) is known to be a key transcriptional factor essential for osteogenesis and especially for cementogenesis. (dentalhypotheses.com)
  • cemento-ossifying fibroma, peripheral cementifying fibroma, ossifying fibro-epithelial polyp, peripheral fibroma with osteogenesis, peripheral fibroma with cementogenesis (8). (marialamslag.nl)
  • This then stimulates the activation of cementoblasts to begin cementogenesis. (wikipedia.org)
  • The cementoblasts then disperse to cover the root dentin area and undergo cementogenesis, laying down cementoid. (wikipedia.org)
  • E2 promoted the function of cementoblasts and cementogenesis by activating extracellular signal-regulated kinase-1/2 pathway. (pocketdentistry.com)
  • It has been recognized that Hertwig's epithelial root sheath (HERS) cells play a crucial role in cementogenesis and root formation. (eurekaselect.com)
  • There is increasing evidence that the cells of the epithelial root sheath synthesize enamel matrix proteins and that these proteins play a fundamental role in cementogenesis and periodontal tissue formation. (hacettepe.edu.tr)
  • To elucidate the fate of the epithelial root sheath during initial cellular cementogenesis, we examined developing maxillary first molars of rats by immunohistochemistry for keratin, vimentin, and tissue non-specific alkaline phosphatase (TNALP) and by TdT-mediated dUTP nick end labeling (TUNEL). (hokudai.ac.jp)
  • and section 3, where initial cellular cementogenesis begins. (hokudai.ac.jp)
  • and (2) epithelial sheath cells do not undergo epithelial-mesenchymal transition during initial cellular cementogenesis. (hokudai.ac.jp)
  • A Great deal of effort has been focused on trying to determine the presence and localization of factors responsible for cementogenesis, as well as in repair and regeneration of periodontal tissues. (imedpub.com)
  • For cementogenesis to begin, Hertwig epithelial root sheath (HERS) must fragment. (wikipedia.org)
  • Hertwig's epithelial root sheath cell behavior during initial acellular cementogenesis in rat molars. (creativebiomart.net)
  • Accelerated reattachment with cementogenesis to dentin, demineralized in situ. (bvsalud.org)
  • Conclusion: These results suggest that in addition to untreated PDL, decellularized PDL also partially supports reattachment (particularly cementogenesis) in pristine extraction sites but not in defect areas. (elsevier.com)
  • The entire process of cementogenesis depends on tooth-root formation. (healthinesslife.com)
  • Here, we analyzed the function of BSP in cementogenesis and periodontal stability by determining the effects of the lack of BSP on tooth formation. (kedstroy.ru)
  • In general, tooth eruption is a complex process that involves a regulated interrelationship of root genesis and cementogenesis. (pocketdentistry.com)
  • While BSP was localized to alveolar bone and odontoblasts early in development, BSP was distinctly localized to the cemental root surface at latter periods coincident with the initiation of root formation and cementogenesis. (nih.gov)
  • These are the lacunae of the former cementocytes, collagen-producing cells that become entrapped in the extracellular matrix they excrete during cementogenesis. (intarch.ac.uk)
  • These findings demonstrated that estrogen administration might be a solution to reduce orthodontically induced root resorption through the activation of extracellular signal-regulated kinase-1/2 pathway and enhancement of cementogenesis. (pocketdentistry.com)
  • Cementogenesis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (childrensmercy.org)
  • Transplantation study of the dental follicle provides a useful model for investigating molecular mechanisms of cementogenesis. (nii.ac.jp)
  • Development of poiodontal regenerative medicine that based on molecular mechanism of cementogenesis. (nii.ac.jp)
  • These findings collectively suggest that BSP and OPN are intimately involved in the sequence of cellular and molecular events accompanying cementogenesis. (nih.gov)
  • The focus of this study was to define the roles of these phosphatases in cementogenesis. (nature.com)
  • PDL-derived cells (PDLCs) express both osteo/cementogenesis and teno/ligamentogenesis genes. (jove.com)
  • This graph shows the total number of publications written about "Cementogenesis" by people in this website by year, and whether "Cementogenesis" was a major or minor topic of these publications. (childrensmercy.org)
  • In addition, for the first time as far as we know, this study provided the direct in vivo evidences for epithelia-originated cementogenesis through EMT. (umich.edu)
  • while simultaneous Wnt1 over-expression advanced Bmpr1a knockout-induced ectopic cementogenesis by further promoting EMT. (umich.edu)