Components of a cell.
The fundamental, structural, and functional units or subunits of living organisms. They are composed of CYTOPLASM containing various ORGANELLES and a CELL MEMBRANE boundary.
A tomographic technique for obtaining 3-dimensional images with transmission electron microscopy.
The use of instrumentation and techniques for visualizing material and details that cannot be seen by the unaided eye. It is usually done by enlarging images, transmitted by light or electron beams, with optical or magnetic lenses that magnify the entire image field. With scanning microscopy, images are generated by collecting output from the specimen in a point-by-point fashion, on a magnified scale, as it is scanned by a narrow beam of light or electrons, a laser, a conductive probe, or a topographical probe.
Microscopy of specimens stained with fluorescent dye (usually fluorescein isothiocyanate) or of naturally fluorescent materials, which emit light when exposed to ultraviolet or blue light. Immunofluorescence microscopy utilizes antibodies that are labeled with fluorescent dye.
Specific particles of membrane-bound organized living substances present in eukaryotic cells, such as the MITOCHONDRIA; the GOLGI APPARATUS; ENDOPLASMIC RETICULUM; LYSOSOMES; PLASTIDS; and VACUOLES.
Fluorescence microscopy utilizing multiple low-energy photons to produce the excitation event of the fluorophore. Multiphoton microscopes have a simplified optical path in the emission side due to the lack of an emission pinhole, which is necessary with normal confocal microscopes. Ultimately this allows spatial isolation of the excitation event, enabling deeper imaging into optically thick tissue, while restricting photobleaching and phototoxicity to the area being imaged.
Cellular processes, properties, and characteristics.
The network of filaments, tubules, and interconnecting filamentous bridges which give shape, structure, and organization to the cytoplasm.
A light microscopic technique in which only a small spot is illuminated and observed at a time. An image is constructed through point-by-point scanning of the field in this manner. Light sources may be conventional or laser, and fluorescence or transmitted observations are possible.
The process of generating three-dimensional images by electronic, photographic, or other methods. For example, three-dimensional images can be generated by assembling multiple tomographic images with the aid of a computer, while photographic 3-D images (HOLOGRAPHY) can be made by exposing film to the interference pattern created when two laser light sources shine on an object.
Slender, cylindrical filaments found in the cytoskeleton of plant and animal cells. They are composed of the protein TUBULIN and are influenced by TUBULIN MODULATORS.
Filamentous proteins that are the main constituent of the thin filaments of muscle fibers. The filaments (known also as filamentous or F-actin) can be dissociated into their globular subunits; each subunit is composed of a single polypeptide 375 amino acids long. This is known as globular or G-actin. In conjunction with MYOSINS, actin is responsible for the contraction and relaxation of muscle.
Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen.
The marking of biological material with a dye or other reagent for the purpose of identifying and quantitating components of tissues, cells or their extracts.
The development and use of techniques to study physical phenomena and construct structures in the nanoscale size range or smaller.
Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.
Fibers composed of MICROFILAMENT PROTEINS, which are predominately ACTIN. They are the smallest of the cytoskeletal filaments.
Proteins which are involved in the phenomenon of light emission in living systems. Included are the "enzymatic" and "non-enzymatic" types of system with or without the presence of oxygen or co-factors.
Microscopy in which the object is examined directly by an electron beam scanning the specimen point-by-point. The image is constructed by detecting the products of specimen interactions that are projected above the plane of the sample, such as backscattered electrons. Although SCANNING TRANSMISSION ELECTRON MICROSCOPY also scans the specimen point by point with the electron beam, the image is constructed by detecting the electrons, or their interaction products that are transmitted through the sample plane, so that is a form of TRANSMISSION ELECTRON MICROSCOPY.
Agents that emit light after excitation by light. The wave length of the emitted light is usually longer than that of the incident light. Fluorochromes are substances that cause fluorescence in other substances, i.e., dyes used to mark or label other compounds with fluorescent tags.
High molecular weight proteins found in the MICROTUBULES of the cytoskeletal system. Under certain conditions they are required for TUBULIN assembly into the microtubules and stabilize the assembled microtubules.
Monomeric subunits of primarily globular ACTIN and found in the cytoplasmic matrix of almost all cells. They are often associated with microtubules and may play a role in cytoskeletal function and/or mediate movement of the cell or the organelles within the cell.
Protein analogs and derivatives of the Aequorea victoria green fluorescent protein that emit light (FLUORESCENCE) when excited with ULTRAVIOLET RAYS. They are used in REPORTER GENES in doing GENETIC TECHNIQUES. Numerous mutants have been made to emit other colors or be sensitive to pH.
A microtubule subunit protein found in large quantities in mammalian brain. It has also been isolated from SPERM FLAGELLUM; CILIA; and other sources. Structurally, the protein is a dimer with a molecular weight of approximately 120,000 and a sedimentation coefficient of 5.8S. It binds to COLCHICINE; VINCRISTINE; and VINBLASTINE.
A partitioning within cells due to the selectively permeable membranes which enclose each of the separate parts, e.g., mitochondria, lysosomes, etc.
The lipid- and protein-containing, selectively permeable membrane that surrounds the cytoplasm in prokaryotic and eukaryotic cells.
Established cell cultures that have the potential to propagate indefinitely.
A technique of inputting two-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer.
Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.
The part of a cell that contains the CYTOSOL and small structures excluding the CELL NUCLEUS; MITOCHONDRIA; and large VACUOLES. (Glick, Glossary of Biochemistry and Molecular Biology, 1990)
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
The systematic study of the complete complement of proteins (PROTEOME) of organisms.
Within a eukaryotic cell, a membrane-limited body which contains chromosomes and one or more nucleoli (CELL NUCLEOLUS). The nuclear membrane consists of a double unit-type membrane which is perforated by a number of pores; the outermost membrane is continuous with the ENDOPLASMIC RETICULUM. A cell may contain more than one nucleus. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.
The process of moving proteins from one cellular compartment (including extracellular) to another by various sorting and transport mechanisms such as gated transport, protein translocation, and vesicular transport.
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
The first continuously cultured human malignant CELL LINE, derived from the cervical carcinoma of Henrietta Lacks. These cells are used for VIRUS CULTIVATION and antitumor drug screening assays.
Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
Recombinant proteins produced by the GENETIC TRANSLATION of fused genes formed by the combination of NUCLEIC ACID REGULATORY SEQUENCES of one or more genes with the protein coding sequences of one or more genes.
Proteins found in the nucleus of a cell. Do not confuse with NUCLEOPROTEINS which are proteins conjugated with nucleic acids, that are not necessarily present in the nucleus.
Semiautonomous, self-reproducing organelles that occur in the cytoplasm of all cells of most, but not all, eukaryotes. Each mitochondrion is surrounded by a double limiting membrane. The inner membrane is highly invaginated, and its projections are called cristae. Mitochondria are the sites of the reactions of oxidative phosphorylation, which result in the formation of ATP. They contain distinctive RIBOSOMES, transfer RNAs (RNA, TRANSFER); AMINO ACYL T RNA SYNTHETASES; and elongation and termination factors. Mitochondria depend upon genes within the nucleus of the cells in which they reside for many essential messenger RNAs (RNA, MESSENGER). Mitochondria are believed to have arisen from aerobic bacteria that established a symbiotic relationship with primitive protoeukaryotes. (King & Stansfield, A Dictionary of Genetics, 4th ed)
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
The rate dynamics in chemical or physical systems.
A cell line derived from cultured tumor cells.
Elements of limited time intervals, contributing to particular results or situations.

Preliminary findings in germinal vesicle transplantation of immature human oocytes. (1/139)

Transplanting a germinal vesicle (GV) from an aged woman's oocyte into a younger ooplasm has been proposed as a possible way to reduce the incidence of oocyte aneuploidy which is considered to be responsible for age-related infertility. In this study, we have assessed the efficiency of each step involved in nuclear transplantation-specifically cell survival, nuclear-cytoplasmic reconstitution, and the capacity of the reconstituted oocytes for in-vitro maturation. In addition, we have evaluated the fertilizability and karyotypic status of the manipulated oocytes by intracytoplasmic sperm injection (ICSI) and fluorescent in-situ hybridization technique respectively. Nuclear transplantation was accomplished with an overall efficiency of 73%. Due to the limited availability of materials, most nuclear transplantation procedures were performed between sibling oocytes. The maturation rate of 62% following reconstitution was comparable with that of control oocytes, as was the incidence of aneuploidy among the reconstituted oocytes. The ICSI results of the reconstituted oocytes yielded a survival rate of 77%, a fertilization rate of 52%, and a satisfactory early embryonic cleavage. Furthermore, in a limited number of observations where the nucleus of an aged oocyte was transferred into a younger ooplasm, there was an appropriate chromosomal segregation. These findings demonstrate that human oocytes reconstituted with GV nuclei are able to undergo maturation, fertilization, and early embryo cleavage, and maintain a normal ploidy. Although in-vitro maturation seems to be a limiting step, this technique would allow us to investigate further the nuclear-ooplasmic relationship during meiotic maturation.  (+info)

Inferring sub-cellular localization through automated lexical analysis. (2/139)

MOTIVATION: The SWISS-PROT sequence database contains keywords of functional annotations for many proteins. In contrast, information about the sub-cellular localization is available for only a few proteins. Experts can often infer localization from keywords describing protein function. We developed LOCkey, a fully automated method for lexical analysis of SWISS-PROT keywords that assigns sub-cellular localization. With the rapid growth in sequence data, the biochemical characterisation of sequences has been falling behind. Our method may be a useful tool for supplementing functional information already automatically available. RESULTS: The method reached a level of more than 82% accuracy in a full cross-validation test. Due to a lack of functional annotations, we could infer localization for fewer than half of all proteins in SWISS-PROT. We applied LOCkey to annotate five entirely sequenced proteomes, namely Saccharomyces cerevisiae (yeast), Caenorhabditis elegans (worm), Drosophila melanogaster (fly), Arabidopsis thaliana (plant) and a subset of all human proteins. LOCkey found about 8000 new annotations of sub-cellular localization for these eukaryotes.  (+info)

Prediction of protein subcellular locations by support vector machines using compositions of amino acids and amino acid pairs. (3/139)

MOTIVATION: The subcellular location of a protein is closely correlated to its function. Thus, computational prediction of subcellular locations from the amino acid sequence information would help annotation and functional prediction of protein coding genes in complete genomes. We have developed a method based on support vector machines (SVMs). RESULTS: We considered 12 subcellular locations in eukaryotic cells: chloroplast, cytoplasm, cytoskeleton, endoplasmic reticulum, extracellular medium, Golgi apparatus, lysosome, mitochondrion, nucleus, peroxisome, plasma membrane, and vacuole. We constructed a data set of proteins with known locations from the SWISS-PROT database. A set of SVMs was trained to predict the subcellular location of a given protein based on its amino acid, amino acid pair, and gapped amino acid pair compositions. The predictors based on these different compositions were then combined using a voting scheme. Results obtained through 5-fold cross-validation tests showed an improvement in prediction accuracy over the algorithm based on the amino acid composition only. This prediction method is available via the Internet.  (+info)

In vivo noninvasive identification of cell composition of intimal lesions: a combined approach with ultrasonography and immunocytochemistry. (4/139)

PURPOSE: We investigated whether differences in cellular composition of the shoulder region of carotid plaque, a cell-rich, debris-free area, can be revealed with computer-driven analysis of ultrasound scans. METHODS: In 26 patients referred for carotid endarterectomy, the shoulder region of plaque eligible for surgical removal was identified with ultrasound scanning. Digital images were obtained and evaluated with a specially developed computer-driven system (Medical Image Processing [MIP]). The gray level distribution of the region of interest (ROI), along with some statistical parameters exploring the spatial distribution of pixels, such as entropy and second angular moment, were analyzed. In the specimen retrieved at surgery, the area corresponding to the ROI was selected. Cryosections were tested at immunocytochemistry with monoclonal antibodies specific to smooth muscle cells (SMCs), macrophages), and lymphocytes. Computerized image analysis was performed to quantify each cellular component of the lesion. RESULTS: Mean gray levels were related positively to the content of SMCs (r = 0.576, P =.002) and negatively to the content of macrophages (r = -0.555, P =.003). Lymphocytes did not show any correlation. Prevalence of SMCs, expressed as the ratio SMC/(SMC + macrophages), was related positively with entropy (r = 0.517, P =.007) and negatively with the second angular moment (r = -0.422, P =.032). The quartiles of gray level were useful for detecting significant differences in terms of cellular composition. CONCLUSIONS: Some cellular features of the shoulder region of plaque are associated with specific videodensitometric patterns evaluated with MIP. This approach enables in vivo noninvasive prediction and monitoring of cell composition of the shoulder region, and could be extended to study of the thickened intima.  (+info)

Prediction of protein subcellular locations using fuzzy k-NN method. (5/139)

MOTIVATION: Protein localization data are a valuable information resource helpful in elucidating protein functions. It is highly desirable to predict a protein's subcellular locations automatically from its sequence. RESULTS: In this paper, fuzzy k-nearest neighbors (k-NN) algorithm has been introduced to predict proteins' subcellular locations from their dipeptide composition. The prediction is performed with a new data set derived from version 41.0 SWISS-PROT databank, the overall predictive accuracy about 80% has been achieved in a jackknife test. The result demonstrates the applicability of this relative simple method and possible improvement of prediction accuracy for the protein subcellular locations. We also applied this method to annotate six entirely sequenced proteomes, namely Saccharomyces cerevisiae, Caenorhabditis elegans, Drosophila melanogaster, Oryza sativa, Arabidopsis thaliana and a subset of all human proteins. AVAILABILITY: Supplementary information and subcellular location annotations for eukaryotes are available at http://166.111.30.65/hying/fuzzy_loc.htm  (+info)

Translational polymorphism as a potential source of plant proteins variety in Arabidopsis thaliana. (6/139)

MOTIVATION: According to scanning model, 40S ribosomal subunits can either initiate translation at start AUG codon in suboptimal context or miss it and initiate translation at downstream AUG(s), thereby producing several proteins. Functional significance of such a protein translational polymorphism is still unknown. RESULTS: We compared predicted subcellular localizations of annotated Arabidopsis thaliana proteins and their potential N-terminally truncated forms started from the nearest downstream in-frame AUG codons. It was found that localizations of full and N-truncated proteins differ in many cases: 12.2% of N-truncated proteins acquired sorting signals de novo and 5.7% changed their predicted subcellular locations (mitochodria, chloroplast or secretory pathway). It is likely that the in-frame downstream AUGs may be frequently utilized to synthesize proteins possessing new functional properties and such a translational polymorphism may serve as an important source of cellular and organelle proteomes.  (+info)

Predicting subcellular localization of proteins using machine-learned classifiers. (7/139)

MOTIVATION: Identifying the destination or localization of proteins is key to understanding their function and facilitating their purification. A number of existing computational prediction methods are based on sequence analysis. However, these methods are limited in scope, accuracy and most particularly breadth of coverage. Rather than using sequence information alone, we have explored the use of database text annotations from homologs and machine learning to substantially improve the prediction of subcellular location. RESULTS: We have constructed five machine-learning classifiers for predicting subcellular localization of proteins from animals, plants, fungi, Gram-negative bacteria and Gram-positive bacteria, which are 81% accurate for fungi and 92-94% accurate for the other four categories. These are the most accurate subcellular predictors across the widest set of organisms ever published. Our predictors are part of the Proteome Analyst web-service.  (+info)

Morphological and physiological changes induced by high hydrostatic pressure in exponential- and stationary-phase cells of Escherichia coli: relationship with cell death. (8/139)

The relationship between a loss of viability and several morphological and physiological changes was examined with Escherichia coli strain J1 subjected to high-pressure treatment. The pressure resistance of stationary-phase cells was much higher than that of exponential-phase cells, but in both types of cell, aggregation of cytoplasmic proteins and condensation of the nucleoid occurred after treatment at 200 MPa for 8 min. Although gross changes were detected in these cellular structures, they were not related to cell death, at least for stationary-phase cells. In addition to these events, exponential-phase cells showed changes in their cell envelopes that were not seen for stationary-phase cells, namely physical perturbations of the cell envelope structure, a loss of osmotic responsiveness, and a loss of protein and RNA to the extracellular medium. Based on these observations, we propose that exponential-phase cells are inactivated under high pressure by irreversible damage to the cell membrane. In contrast, stationary-phase cells have a cytoplasmic membrane that is robust enough to withstand pressurization up to very intense treatments. The retention of an intact membrane appears to allow the stationary-phase cell to repair gross changes in other cellular structures and to remain viable at pressures that are lethal to exponential-phase cells.  (+info)

A non-biological entity with a cellular organizational structure (also known as a cellular organization, cellular system, nodal ... efficient use of cellular organizational planning. A cellular business structure is partly related, philosophically speaking, ... Tony Hsieh, the CEO of Zappos, has remarked that his business considers cellular-type self-management groups to be a key to its ... This structure, as applied in areas such as business management, exists in direct contrast to traditional hierarchical ...
CCS provide steep vertical mechanically stabilized earth structures (either gravity or reinforced walls) for steep faces, walls ... cellular confinement systems. Today cellular confinement systems are typically made from strips 50-200 mm wide, ultrasonically ... Cellular Confinement Systems (CCS) have been used to improve the performance of both paved and unpaved roads by reinforcing the ... The cellular confinement system was used for load support, slope erosion control and channel lining and earth retention ...
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The use of steel girders with web openings (SBWOs) for structures such as industrial buildings has proven to be extensive. ... Cellular beams are usually made of structural steel, but can also be made of other materials. The cellular beam is a structural ... The difference between cellular beam and castellated beam is the visual characteristic. A cellular beam has round openings ( ... Cellular beam is a further development of the traditional castellated beam. The advantage of the steel beam castellation ...
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... (RCCM) are three-dimensional lattices of modular structures that can be ... Site locations are locally constrained, yielding structures that merge desirable features of carbon fiber composites, cellular ... These structures have previously been implemented only in relatively dense engineered materials. For the ultralight regime the ... Cellular composites extend stretch-dominated lattices to the ultralight regime (below ten milligrams per cubic centimeter). ...
... , or acellular life is life that exists without a cellular structure for at least part of its life cycle. ... The corresponding cellular life name would be Cytota. Non-cellular organisms and cellular life would be the two top-level ... The primary candidates for non-cellular life are viruses. Some biologists consider viruses to be organisms, but others do not. ... Tsagris, E. M.; Martínez De Alba, A. E.; Gozmanova, M; Kalantidis, K (2008). "Viroids". Cellular Microbiology. 10 (11): 2168-79 ...
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"Tall structures and their impact on broadcast and other wireless services" (PDF). "5G-Netzausbau wird "unfassbar teuer"" (in ... The cellular V2X technology can be traced back to the early 2000s when the idea of using cellular networks for vehicle-to- ... Cellular V2X uses 3GPP standardized 4G LTE or 5G mobile cellular connectivity to exchange messages between vehicles, ... Cellular V2X is a 3GPP standard for V2X applications such as self-driving cars. It is an alternative to 802.11p, the IEEE ...
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The first structure to be solved by this method was that of sperm whale myoglobin by Sir John Cowdery Kendrew. In this ... On the other hand, a protein may interact briefly and in a reversible manner with other proteins in only certain cellular ... The crystal structures of complexes, obtained at high resolution from different but homologous proteins, have shown that some ... The molecular structures of many protein complexes have been unlocked by the technique of X-ray crystallography. ...
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Aoki-Kinoshita K.F. (2013). "Using databases and web resources for glycomics research". Molecular & Cellular Proteomics. 12 (4 ... The main data stored in CSDB are carbohydrate structures of bacterial, fungal, and plant origin. Each structure is assigned to ... Molecular structures of glycans, glycopolymers and glycoconjugates: primary structure, aglycon information, polymerization ... Automated NMR-based structure elucidation (GRASS: generation, ranking and assignment of saccharide structures). Statistical ...
Structure-based Function and Regulation". Journal of Biological Chemistry. 289 (24): 16615-16623. doi:10.1074/jbc.R114.563148. ... Cellular respiration, Biomolecules). ...
Ideally, the structure of a drug target is known, which allows for structure-based pharmacophore modeling. A structure-based ... When coupled with mass spectrometry, this technique is referred to as the Mass Spectrometry Cellular Thermal Shift Assay (MS- ... Compound structures are superimposed virtually and common elements are scored on the basis of their tendency toward bioactivity ... A second challenge arises from the decision of how to superimpose analog structures. A common approach is to use a least- ...
... s (NOXes) are one of the major sources of cellular reactive oxygen species (ROS), and they still are the focus of ... Panday A, Sahoo MK, Osorio D, Batra S (January 2015). "NADPH oxidases: an overview from structure to innate immunity-associated ... DUOX1 DUOX2 The whole structure of the membrane-bound vascular enzyme is composed of five parts: two cytosolic subunits ( ... differing in biochemical structure and functions. Neutrophilic NADPH oxidase produces superoxide almost instantaneously, ...
2. Okwute, S.K. OKOGUN, J.I. and Okorie, D.A. 1984 Revised Structure and Synthesis of Piperolein acids; Guineensine and ... Guineensine inhibits the cellular reuptake of anandamide and 2-arachidonoylglycerol in a mouse model (EC50 = 290 nM). This ...
The tertiary and quaternary structures of PTGS1 (COX-1) and PTGS2 (COX-2) enzymes are almost identical. Each subunit has three ... Wu T, Wu H, Wang J, Wang J (2011). "Expression and cellular localization of cyclooxygenases and prostaglandin E synthases in ... Picot D, Loll PJ, Garavito RM (January 1994). "The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1 ...
The neo-colonial structures and discourses are already part of the different "postcolonial" cultures. The postcolonial era in ... cellular coverage, electricity), a skills dimension (including education legacy regarding computer training, social capital ... Yet, the neo-colonial structures that are still rampant in the postcolonial societies. Although the nation-state might forward ... Beyond the GDPR, one of the structured regulations is the UK's Information Commissioner's Office (ICO) Children Code (formally ...
It has also been used to study the structure of Plasmodium falciparum, a particularly pathogenic form of malaria. In 1986, P. A ... and biological cells and cellular components, a more detailed approach is necessary. The Mie solution is named after its ...
The normal cellular gene was called c-src (cellular-src). This discovery changed the current thinking about cancer from a model ... This induces long-range allostery via protein domain dynamics, causing the structure to be destabilized, resulting in the ... It is believed that at one point an ancestral virus mistakenly incorporated the c-Src gene of its cellular host. Eventually ... Proto-oncogene tyrosine-protein kinase Src, also known as proto-oncogene c-Src, or simply c-Src (cellular Src; pronounced "sarc ...
The sequences and structures of N proteins from different coronaviruses, particularly the C-terminal domains, appear to be well ... "Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic ... A third small domain at the C-terminal tail appears to have an ordered alpha helical secondary structure and may be involved in ... N also serves as a chaperone protein for the formation of RNA structure in the genomic RNA. Synthesis of genomic RNA appears to ...
They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation ... and cellular growth and division. The protein encoded by this gene is a component of the 17S U2 snRNP complex; it plays an ...
Microtubules are protein structures that are part of the cytoskeleton and are necessary for cells to have diverse, complex ... Platelets are cellular fragments formed from protrusions on megakaryocytes that enable blood clotting. Blood symptoms have not ... CENPF also has a role in orienting long, cylindrical structures called microtubules to form thin cell protrusions called cilia ... in order to orient microtubules correctly to form thin cellular projections called cilia. Most cilia are primary cilia, which ...
Lugovskoy AA, Zhou P, Chou JJ, McCarty JS, Li P, Wagner G (December 1999). "Solution structure of the CIDE-N domain of CIDE-B ... Caspase 3 is responsible for cellular differentiation, although it is unclear how this kind of protein can promote the cell ... Uegaki K, Otomo T, Sakahira H, Shimizu M, Yumoto N, Kyogoku Y, Nagata S, Yamazaki T (April 2000). "Structure of the CAD domain ... Zhou P, Lugovskoy AA, McCarty JS, Li P, Wagner G (May 2001). "Solution structure of DFF40 and DFF45 N-terminal domain complex ...
TGF-β regulates a variety of different cellular developmental processes including growth, differentiation, proliferation, and ... PDBe-KB provides an overview of all the structure information available in the PDB for Human Death domain-associated protein 6 ... "PML is critical for ND10 formation and recruits the PML-interacting protein daxx to this nuclear structure when modified by ... where it is interacting with some subnuclear structures. Several additional interacting proteins are known, but not always is ...
3GPP TS 36.212, version 8.8.0, page 14 "Digital Video Broadcast (DVB); Frame structure, channel coding and modulation for a ... One of the earliest commercial applications of turbo coding was the CDMA2000 1x (TIA IS-2000) digital cellular technology ... Also interleavers hide the structure of errors; without an interleaver, more advanced decoding algorithms can take advantage of ... "Digital Video Broadcast (DVB); Second generation framing structure, channel coding and modulation systems for Broadcasting, ...
The primary structure, or amino acid sequence identity, of the proteins between paralogs is ~60% identical and between ... Beckmann J, Schubert R, Chiquet-Ehrismann R, Müller DJ (June 2013). "Deciphering teneurin domains that facilitate cellular ... At E8.5, Ten-m3 is expressed at the caudal forebrain, the midbrain region and structures outside of the CNS, including the ... This creates a high dorsal to low ventral gradient topography mapping between the two structures. In Ten-m3 null mutant mice, ...
In general, the complex molecules that make up cellular structures are constructed step-by-step from smaller and simpler ... Most of the structures that make up animals, plants and microbes are made from four basic classes of molecules: amino acids, ... Each different protein has a unique sequence of amino acid residues: this is its primary structure. Just as the letters of the ... The three main purposes of metabolism are: the conversion of the energy in food to energy available to run cellular processes; ...
... extra-cellular polymers, nectar, root exudates and leachates, dissolved organic matter, extra-cellular matrix, mucilage). The ... Pyramid structure can vary across ecosystems and across time. In some instances biomass pyramids can be inverted. This pattern ... At different levels in the hierarchy of life, such as the stability of a food web, "the same overall structure is maintained in ... Population structure, migration rates, and environmental refuge for prey are other possible causes for pyramids with biomass ...
Tycko B, Morison IM (September 2002). "Physiological functions of imprinted genes". Journal of Cellular Physiology. 192 (3): ... an extraembryonic structure that nourishes the embryo in a manner analogous to the mammalian placenta. Unlike the embryo, the ... proportion of mammalian genes they play an important role in embryogenesis particularly in the formation of visceral structures ...
Mushegian, A. R.; Koonin, E. V. (1996-09-17). "A minimal gene set for cellular life derived by comparison of complete bacterial ... A common explanation for these manipulative abilities is their consistently compact and efficient genomic structure. These ... Hinegardner R (1968). "Evolution of cellular DNA content in teleost fishes". American Naturalist. 102 (928): 517-523. doi: ... One obligate endosymbiont of leafhoppers, Nasuia deltocephalinicola, has the smallest genome currently known among cellular ...
Simon JH, Gaddis NC, Fouchier RA, Malim MH (Dec 1998). "Evidence for a newly discovered cellular anti-HIV-1 phenotype". Nature ... The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core ... Coux O, Tanaka K, Goldberg AL (1996). "Structure and functions of the 20S and 26S proteasomes". Annual Review of Biochemistry. ... The proteasomes form a pivotal component for the ubiquitin-proteasome system (UPS) and corresponding cellular Protein Quality ...
The BSF focuses on bioenergy, environmental and soil remediation and includes systems biology, microbial and cellular biology ... Buildings and structures in Benton County, Washington, Richland, Washington, Research institutes in Washington (state), ...
Cell-cell adhesion complexes are required for simple epithelia in higher organisms to maintain structure, function and polarity ... Catenins play roles in cellular organization and polarity long before the development and incorporation of Wnt signaling ... it is nonetheless an important player in cellular organization, function and growth. α-catenin participates in the formation ... although β-catenin substitutes for plakoglobin at many cellular junctions. Keratinocytes engineered to not express alpha- ...
Molecular and Cellular Biology. 15 (9): 4898-907. doi:10.1128/MCB.15.9.4898. PMC 230736. PMID 7651409. Gui JF, Lane WS, Fu XD ( ... Gene Structure and Expression. 1625 (2): 141-52. doi:10.1016/S0167-4781(02)00600-0. PMID 12531473. Tran Q, Roesser JR (February ... Molecular and Cellular Biology. 20 (9): 3049-57. doi:10.1128/MCB.20.9.3049-3057.2000. PMC 85584. PMID 10757789. Monsalve M, Wu ... Molecular and Cellular Biology. 23 (21): 7437-47. doi:10.1128/MCB.23.21.7437-7447.2003. PMC 207616. PMID 14559993. Beausoleil ...
Fang CT, Kuo HH, Pan TS, Yu FC, Yih LH (October 2016). "HSP70 regulates the function of mitotic centrosomes". Cellular and ... Milner CM, Campbell RD (1990). "Structure and expression of the three MHC-linked HSP70 genes". Immunogenetics. 32 (4): 242-251 ... "Genomic structure of the spermatid-specific hsp70 homolog gene located in the class III region of the major histocompatibility ...
These two ways in which fragmentation is used in cellular processes describe normal cellular functions and common laboratory ... "Structure and Function of Mammalian DNA Ligases." Mutation Research/DNA Repair 407.1 (1998): 1-9. Print. Hung, Mien-Chie, and ... Cellular and nuclear shrinkage, chromatin condensation and fragmentation, formation of apoptotic bodies and phagocytosis by ...
Spinach is a synthetically derived RNA aptamer born out of the need for a way of studying the role of RNAs at the cellular ... An adapted structure, which includes two binding sites, limits fluorescence of the aptamer to (1) the fluorophore and (2) the ... This structure, 4-hydroxybenzylidene imidazolinone (HBI) was the basis for the synthetic analogue used in the SELEX studies. ... Spinach is an 84-nucleotide-long structure with two helical strands and an internal bulge with a G-quadruplex motif. It is at ...
A similar structure has also been used by the AP when referring to virus variants, for example, referring to it as the "Delta ... Cellular & Molecular Immunology. 17 (5): 554. doi:10.1038/s41423-020-0372-4. PMC 7091741. PMID 32024976. Chan JF, Yuan S, Kok ...
Another cellular enzyme, RNAse L-also induced by interferon action-destroys RNA within the cells to further reduce protein ... Nagata S, Mantei N, Weissmann C (October 1980). "The structure of one of the eight or more distinct chromosomal genes for human ... ISBN 978-981-02-3148-4. Tan YH, Armstrong JA, Ke YH, Ho M (September 1970). "Regulation of cellular interferon production: ... Gray PW, Goeddel DV (August 1982). "Structure of the human immune interferon gene". Nature. 298 (5877): 859-63. Bibcode: ...
The structure of Φ29 is composed of seven main proteins: the terminal protein (p3), the head or capsid protein (p8), the head ... Errington, Jeffery; van der Aart, Lizah T (2020-05-11). "Microbe Profile: Bacillus subtilis: model organism for cellular ... This novel structure system has inspired ongoing research in nanotechnology, drug delivery, and therapeutics. In nature, the ... Φ29 is one of many phages with a DNA polymerase that has a different structure and function compared to standard DNA ...
... (or virological synapse) is a molecularly organized cellular junction that is similar in some aspects to ... By recruiting the receptors and viral particles at the point of contact, these synaptic structures significantly enhance the ...
Mallette, Frédérick A.; Richard, Stéphane (2012-11-29). "JMJD2A promotes cellular transformation by blocking cellular ... as derived from their related structure and function). The miR-137 clan contains two members: miR-137 and miR-234; the total ... which leads to change in folding and the secondary structure of miR-137. This alteration is believed to cause inefficient ... and that restoration of its expression leads to cellular growth arrest and senescence in pancreatic cancer cells. MicroRNA ...
and structured as a joint venture between Telefónica and Liberty Global. Between 1985 and 1989, John Carrington was the CEO of ... "Cellular Tower and Signal Map". CellMapper. Retrieved 1 March 2022. "O2 enters U.K. broadband market with purchase of Be". O2 ... Cellnet was established in 1985 as a joint subsidiary of BTCR, British Telecom Cellular Radio, providing the engineering ... It was during this period that Carrington launched Cellnet's first cellular service, following innovative development work by ...
... refer to conserved RNA structures that are associated with genes acting in the photosynthetic reaction ... Molecular and cellular biology stubs). ... "Comparative genomics reveals 104 candidate structured RNAs from ...
In this paper, a novel S-based TPMS hollow isotropic cellular structure is proposed with both s... , Find, read and cite all ... Cellular structures are regarded as excellent candidates for lightweight-design, load-bearing, and energy-absorbing ... The hollow cellular structure is designed with Boolean operation based on the Fischer-Koch (S) implicit triply periodic minimal ... Hollow cellular structure; triply periodic minimal surfaces; isotropic property; energy absorption; load-bearing ...
5: Cellular Structure is shared under a not declared license and was authored, remixed, and/or curated by LibreTexts. ... 5.01:_Why_It_Matters-_Cellular_Structure : property get [Map MindTouch.Deki.Logic.ExtensionProcessorQueryProvider+,,c__ ... Cellular_Structure : property get [Map MindTouch.Deki.Logic.ExtensionProcessorQueryProvider+,,c__DisplayClass228_0., ... Cellular_Structure : property get [Map MindTouch.Deki.Logic.ExtensionProcessorQueryProvider+,,c__DisplayClass228_0., ...
Courses▻PhDs and Research Masters▻Structured Programmes▻College of SCIENCE and Engineering▻Cellular and Molecular Biology ( ... Structured PhD in Cellular and Molecular Biology. Applications are made online via the University of Galway Postgraduate ... This PhD programme in Cellular and Molecular Biology addresses this need by providing a structured training programme with the ... Optional CMB6150: Cellular & Molecular Biology - 0 Credits - Semester 3. Optional BI5105: Current Topics in Cellular and ...
... very like a honeycomb structure. According to thermal insulation principle of porous materials, the thinner cell wall, the ...
Cellular structures with deterministic architecture can be considered as example of periodic structures. Periodic structures ... Cellular structures exhibit a number of desirable multifunctional properties, which make them attractive in a variety of ... This work presents a methodology for the analysis of the dynamic behavior of periodic cellular structures, which allows the ... Numerical and experimental results show the potential of periodic cellular structures as mechanical filters and/or isolators of ...
Nikon Introduces Reduced-Halo Phase Contrast Technique - Makes Unstained Living Cellular Structures Clearly Visible. Mai 8, ... Nikon Introduces Reduced-Halo Phase Contrast Technique - Makes Unstained Living Cellular Structures Clearly Visible ... the new Nikon method allows the clear imaging of minute structures inside living cells and other thick specimens that used to ... microscope optics reduce the unwanted halos that are routinely caused by large phase shifts around the periphery of cellular ...
Effects of sound exposure on general cellular structure. The OHCs could swell and contract so that their bases with their nerve ... 1998a) Vital staining of the hearing organ: visualization of cellular structure with confocal microscopy. Neuroscience 83:215- ... Using laser scanning confocal microscopy, stimulus-induced changes of the cellular structure of the hearing organ were ... Quantitative measurements of motion were measured using cellular structures that could be followed throughout the stack. ...
This amazing tool decrease in benefit to the cellular wall structure associated with solution cellular creates your wilted look ... Herb check it out Cellular Structure. by Provia , Jan 6, 2021 , Uncategorized , 0 comments ... Just what are the Qualities Regarding the Ribosomes In plant Cellular?. Remove cells had gotten various check it out organelles ... They metabolise substances that are beneficial from the cellular in order to store as well as waste people that is adverse. ...
... cellular materials; design of skeletons and other supportive structures; locomotion (walking, running, flying, swimming); power ... To extract principles of biological structures and reformulate them as engineering structures. To use concepts from biology to ... Biological fibres, fillers and ceramics; composites; soft structures; inflatable structures; mechanical properties and testing ... adaptive structures; smart materials; neural networks; genetic algorithms and programming; structures made by animals and their ...
Photocontrolled DNA nanotubes as stiffness tunable matrices for controlling cellular behavior Soumya Sethi, Tomoko Emura, Kumi ... structure, functions and applications. The collection focuses on self-assembly, structure-function relationships, physical ... Schematic representation of the effect of nucleases on the stability of a DNA structure, which is shown to break along the ... DNA nanotechnology is a rapidly growing field that utilizes DNA as a structural molecule to design a palette of structures at ...
Here, we provide guidance on how to use SRM techniques advantageously for investigating cellular structures and dynamics to ... Nonlinear structured-illumination microscopy with a photoswitchable protein reveals cellular structures at 50-nm resolution. ... Imaging cellular structures in super-resolution with SIM, STED and localisation microscopy: a practical comparison. Sci. Rep. 6 ... Investigating cellular structures at the nanoscale with organic fluorophores. Chem. Biol. 20, 8-18 (2013). ...
Kenny Lu and Gina Bria: How to Improve Cellular Hydration With Structured Water Kenny Lu and Gina Bria: How to Improve Cellular ... Hydration With Structured Water. Did you know daily movement is critical to cellular hydration?. In this episode of The ... 22:00: How does spring water stay structured?. 26:19: What is mother water?. 27:25: Are we seeing water the right way?. 28:02: ... 1:01:01: How easy is it to introduce structured water into your diet?. 1:02:44: How can you find a balance between diets?. 1:06 ...
... cellular structure, organization, and respiration; biodiversity, biomes, communities, conservation, ecosystems; meiosis and ... Questions on both tests may include problems referring to Cellular and Molecular Biology, Ecology, Evolution and Diversity, ... cell structure, photosynthesis, and respiration (Biology-M). The student should confer with his or her high school Biology ... inheritance patterns; Mendelian, molecular, and population genetics; development, function, and structure of plant and animal ...
cell structure and function, cell cycle, cell replication. DNA replication, genes to proteins. DNA technology, genomics, ... metabolism and enzymes; cellular respiration Animal biology form and function. homeostasis and thermoregulation. osmoregulation ... Topics covered include cell structure and function, DNA replication and the flow of genetic information, enzyme function, ...
Cell structure; Mitosis and cellular reproduction; Meiosis and the production of gametes; DNA structure and replication; Gene ... Neuron structure and function; Central and peripheral nervous systems; Glands and hormone action; Homeostasis and feedback ...
... is formed by melt pools of different dimensions with titanium segregation at the walls of the cellular-dendritic structure in a ... matrix of ? phase of body-centered cubic (BCC) structure. The hardness of the PA samples varied from 173 to 224 HV0.2, while ...
The cellular structures were visualized by phalloidin-rhodamine staining. Rat primary cell cultures were incubated with rabbit ... and they function in recognition and binding of molecular structures. The crystal structure of mouse Kim-1 was elucidated (43 ... Structures of T cell immunoglobulin mucin protein 4 show a metal-ion-dependent ligand binding site where phosphatidylserine ... Epithelial structures in different organs perform diverse and complex tasks but display stereotyped responses to injury. The ...
4 Cell Structure and Function 5 Membrane Structure and Function 6 Metabolism: Energy and Enzymes 7 Photosynthesis 8 Cellular ... 24 Flowering Plants: Structure and Organization 25 Flowering Plants: Nutrition and Transport 26 Flowering Plants: Control of ... 9 The Cell Cycle and Cellular Reproduction 10 Meiosis and Sexual Reproduction 11 Mendelian Patterns of Inheritance 12 Molecular ...
... which form structures like bones and skin.,/p,\n,h2 id=tab1 ,Looking at cell structure,/h2,\n,p,A cell has three main parts ... Nucleus: The nucleus controls cellular activity. Its like the brains behind the cell, and it holds the cells genetic material ... which form structures like bones and skin.,/p,\n,h2 id=tab1 ,Looking at cell structure,/h2,\n,p,A cell has three main parts ... "Basic structures of plant and animal cells. width=389/,,div class=imageCaption,Basic structures of plant and animal ...
In addition, like all virtual screening methods used for drug design, structure-based virtual screening can focus on curated ... In this review, we introduce the protein-ligand docking methods used for structure-based drug design and other biological ... The docking methods used in structure-based virtual database screening offer the ability to quickly and cheaply estimate the ... Unsurprisingly, they are involved in cellular aging and cancers [144]. Alcaro et al. used a hybrid approach to screen a ...
The aluminosilicates also have a glassy structure. Contrary to artificial teeth in resin, the colour of tooth ceramic remains ... Zhu, Xiaolong; Chen, Jun; Scheideler, Lutz; Altebaeumer, Thomas; Geis-Gerstorfer, Juergen; Kern, Dieter (2004). "Cellular ... as they are similar to the main mineral phase of bone in structure and chemical composition. Such synthetic bone substitute or ... This can be achieved by the inclusion of grain refining dopants and by imparting defects in the crystalline structure through ...
In-building Cellular * Enterprise LAN & WLAN , RUCKUS® * Enterprise Networks Structured Cabling * Data Centers ... In-building Cellular In-building Cellular. Expand coverage for cellular services with distributed antenna systems (DAS) and ... In-Building Cellular Systems In-Building Cellular Systems. Expand coverage for cellular services with distributed antenna ... Enterprise Networks Structured Cabling Enterprise Networks Structured Cabling. Build a reliable building connectivity ...
Structure of biomolecular assemblies and x-ray physics. more. Prof. Dr. Sarah Köster. Cellular Biophysics. more. Prof. Dr. ... Tim Salditts group is directed at structure analysis of soft and biological matter, from macromolecular assemblies to cells ... Sarah Köster is dedicated to nanoscale imaging of cellular dynamics, by combining close-to-physiological sample environments ...
Song MD, Maesaki S, Wachi M, Takahashi T, Doi M, Ishino F, Primary structure and origin of the gene encoding the beta-lactam- ... Escherichia coli and Salmonella typhimurium: cellular and molecular biology. Washington, DC: American Society for Microbiology ... Musser JM, Kroll JS, Granoff DM, Global genetic structure and molecular epidemiology of encapsulated Haemophilus influenzae. ... Genetic structure and variation in natural populations of Escherichia coli. In: Neidhardt FC, Ingraham JL, Low KB, Magasanik B ...
Molecular-structure; Lung-tissue; Lung; Lung-function; Animals; Laboratory-animals; Cell-function; Cellular-function; Cell- ... The effects of PQ on cellular processes and biological pathways were investigated by analyzing proteome in the lung tissues in ...
CELLULAR STRUCTURES. ESTRUCTURAS CELULARES. ESTRUTURAS CITOPLASMÁTICAS. CYTOPLASMIC STRUCTURES. ESTRUCTURAS CITOPLASMATICAS. ... CELL MEMBRANE STRUCTURES. ESTRUCTURAS DE LA MEMBRANA CELULAR. ESTRUTURAS DO NÚCLEO CELULAR. CELL NUCLEUS STRUCTURES. ... QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP. RELACION ESTRUCTURA-ACTIVIDAD CUANTITATIVA. REPLICAÇÃO DE SEQUÊNCIA AUTO- ... CHROMOSOME STRUCTURES. ESTRUCTURAS CROMOSOMICAS. ESTRUTURAS DA MEMBRANA CELULAR. ...
Cytoplasm, extra-cellular space (9) Inclusion Bodies. Other. Tubular structures in cytoplasm (9) ...
Atomistic autophagy: the structures of cellular self-digestion. Cell 157(2):300-311, 2014. ... Viral E3 ubiquitin ligase-mediated degradation of a cellular E3: viral mimicry of a cellular phosphorylation mark targets the ... Cover story; Preview, Structure 17:321-322.. Duda DM, Borg LA, Scott DC, Hunt HW, Hammel M, Schulman BA. Structural Insights ... Structure of a glomulin-RBX1-CUL1 complex: inhibition of a RING E3 ligase through masking of its E2-binding surface. Mol Cell ...
The role of peroxisomes in mammalian cellular metabolism. . J. Inherit. Metab. Dis. ... Structure of the peroxisomal ubiquitin ligase complex.. (A) Cartoon model of the structure of the ubiquitin ligase complex from ... Structure of the peroxisomal ubiquitin ligase complex.. (A) Cartoon model of the structure of the ubiquitin ligase complex from ... Structure and function of the peroxisomal ubiquitin ligase complex Peiqiang Feng 0000-0003-1371-0290 ...
  • Structures called mitochondria provide most of a cell's energy. (nih.gov)
  • The tRNA Leu(UUR) molecule is present in cellular structures called mitochondria. (medlineplus.gov)
  • The nanometer scale of biological electron microscopy lies between the realms of live-cell optical microscopy and atomic-scale structural tools that require extraction and purification of cellular components. (nih.gov)
  • At its core, the Taraska lab develops and uses advanced fluorescence and electron microscopy methods along with structural, biochemical, cellular, and biophysical tools to investigate the nanometer-scale organization of proteins that regulate key cellular events. (nih.gov)
  • This FOA solicits applications to establish Centers for High-Throughput Structure Determination that will become the backbone of the NIGMS PSI:Biology network for high-throughput-enabled structural biology. (nih.gov)
  • The structural and functional organisation of the nervous system at cellular, tissue, system and integrative levels. (otago.ac.nz)
  • CommScope premium structural support solutions reinforce your structure and optimize antenna performance. (commscope.com)
  • The centers must be able to provide capabilities for high-throughput structure determination on the order of those that have been developed during previous phases of the Protein Structure Initiative (PSI), e.g., ~ 200 structures per year deposited in the Protein Databank (PDB). (nih.gov)
  • Current research includes development of techniques for (1) determining the tertiary and quaternary structures of macromolecular assemblies, (2) visualizing 3D ultrastructure, (3) mapping the elemental composition of subcellular compartments quantitatively, and (4) studying bionanoparticles and their interactions with cells. (nih.gov)
  • The research of Prof. Dr. Tim Salditt's group is directed at structure analysis of soft and biological matter, from macromolecular assemblies to cells and tissues, see research pages of the Salditt group. (uni-goettingen.de)
  • ANAT 242 will be delivered as modules directed at distinct levels: anatomical structure, cellular organization, molecular events, systems organization and ethics, supported by laboratory teaching. (otago.ac.nz)
  • The first will provide a reasonably detailed and systematic overview of the anatomical organization of the brain, peripheral nervous system and their related structures. (otago.ac.nz)
  • The second module is focused on the cellular organization of the nervous system, and will consider the specialized structure of a variety of cells that constitute the nervous system. (otago.ac.nz)
  • To introduce the materials, structures and mechanisms of natural organisms. (bath.ac.uk)
  • To show how organisms can be analysed as engineering structures using standard techniques. (bath.ac.uk)
  • We aim to fill this gap by developing and using new ultra-high resolution imaging tools to determine the nano-scale structures, organizations, and dynamics of molecules that are important for the biology of membrane traffic in neurons, endocrine, and immune cells. (nih.gov)
  • The structure and spontaneous curvature of clathrin lattices at the plasma membrane. (nih.gov)
  • The entrance feels as though an orifice inside a cellular membrane that allows just travel document owners right the way through. (arafaoasis.com)
  • This PhD programme will focus on the molecular mechanisms that maintain cellular homeostasis and on the mechanisms that dictate tissue and organism-level homeostasis. (universityofgalway.ie)
  • This RFA, SCORs in Pathobiology of Fibrotic Lung Disease, Pathobiology of Lung Development, and Cellular and Molecular Mechanisms of Asthma, is related to the priority areas of Occupational Safety and Health, Environmental Health, Maternal and Infant Health, Diabetes and Chronic Disabling Diseases and Immunization and Infectious Diseases. (nih.gov)
  • The finite element method is further conducted to analyze the static mechanical performance of hollow cellular structure considering the size effect. (techscience.com)
  • Such dynamic properties are here exploited to provide cellular structures with the capability of behaving as directional, pass-band mechanical filters, thus complementing their well documented multifunctional characteristics. (gatech.edu)
  • Numerical and experimental results show the potential of periodic cellular structures as mechanical filters and/or isolators of vibrations. (gatech.edu)
  • A gap exists between understanding protein structures and their dynamic cellular contexts. (nih.gov)
  • Moreover, our data suggest that the provision of the EIAV Tat protein in trans potentiates read-through transcription through the 3' viral long terminal repeat (3' LTR), thus suggesting activation of downstream-located cellular genes. (nih.gov)
  • Brains processed with B Ex showed reduced cell death, preserved anatomical and cell architecture, restored blood vessel structure and circulatory function, restored glial inflammatory responses, spontaneous neural activity at synapses and active cerebral metabolism, compared to brains perfused with a control solution, which rapidly decomposed. (nih.gov)
  • Topics covered include cell structure and function, DNA replication and the flow of genetic information, enzyme function, metabolism and physiology of microorganisms, plants, and animals. (sfu.ca)
  • The area of Cellular and Molecular Biology has developed rapidly during the past decade. (universityofgalway.ie)
  • Questions on both tests may include problems referring to Cellular and Molecular Biology, Ecology, Evolution and Diversity, Genetics, and Organismal Biology. (testprepreview.com)
  • The Laboratory of Molecular and Cellular Imaging, led by Dr. Justin Taraska, studies how vesicles fuse with and are captured from the cell surface in mammalian cells. (nih.gov)
  • As a result, when observing or photographing unstained specimens or living tissue, the new Nikon method allows the clear imaging of minute structures inside living cells and other thick specimens that used to be obscured by bright rings of light. (nikon.com)
  • The research group of Prof. Dr. Sarah Köster is dedicated to nanoscale imaging of cellular dynamics, by combining close-to-physiological sample environments and in situ imaging. (uni-goettingen.de)
  • The effects of PQ on cellular processes and biological pathways were investigated by analyzing proteome in the lung tissues in comparison with the control. (cdc.gov)
  • These include ultra-light structures, thermal and acoustic insulators, and impact amelioration systems, among others. (gatech.edu)
  • The authors set out to prepare cellular vitreous carbon (CVC) foams with varying thermal and physical properties. (thermtest.com)
  • To extract principles of biological structures and reformulate them as engineering structures. (bath.ac.uk)
  • Understand fundamental concepts of biological design such as scaling, hierarchy of structures and materials, designing for high strains and low loads, energy conservation, adaptive design, damage control. (bath.ac.uk)
  • Furthermore, the central question of how these processes are carefully balanced even under drastic changes in cellular activity is unclear. (nih.gov)
  • Compared with the solid counterpart, the S-based hollow cellular structure has a higher elastic modulus, better load-bearing and energy absorption characteristics. (techscience.com)
  • The anisotropy and effective elasticity properties of cellular structures are evaluated with the numerical homogenization method. (techscience.com)
  • Numerical results of the Zener ratio proved that the S-based hollow cellular structure tends to be isotropic, even better than the sheet-based Gyroid TPMS. (techscience.com)
  • Because serotype analysis of relatively few surface structures does not provide robust data for estimating overall levels of chromosomal diversity and relationships among strains, the primary research tool used to examine the population genetics of emerging bacterial pathogens has been multilocus enzyme electrophoresis ( 10 , 11 ). (cdc.gov)
  • The Cellular and Supramolecular Structure and Function (CSSF) Section develops new methods based on electron microscopy and related techniques. (nih.gov)
  • Read more about the research topics of interest to the Cellular and Supramolecular Structure and Function. (nih.gov)
  • Read more about the resources available to the Cellular and Supramolecular Structure and Function. (nih.gov)
  • See a list of publications authored by the Cellular and Supramolecular Structure and Function. (nih.gov)
  • Because the structure and function of the organ of Corti can be monitored for several hours ( Ulfendahl and Flock, 1998 ), both immediate and long-term effects of acoustic overstimulation can be studied. (jneurosci.org)
  • Structure and function of the eustachian tube (ET). (nih.gov)
  • Calcium signaling drives mitochondrial and metabolic changes and is likely the mediator of the cellular response in retinal neurodegeneration. (nih.gov)
  • Restoring Cellular Energetics Promotes Axonal Regeneration and Functional Recovery after Spinal Cord Injury. (nih.gov)
  • Researchers have developed a high-tech support system that can keep a large mammalian brain from rapidly decomposing in the hours after death, enabling study of certain molecular and cellular functions. (nih.gov)
  • With funding through the National Institutes of Health BRAIN Initiative , researchers developed a way to deliver an artificial blood supply to the isolated postmortem brain of a pig, preventing the degradation that would otherwise destroy many cellular and molecular functions and render it unsuitable for study. (nih.gov)
  • Molecular and cellular changes in rod photoreceptors are detectable in a mouse model of retinal degeneration several days prior to observable morphological changes, according to researchers at the National Eye Institute. (nih.gov)
  • Using the widely studied retinal neurodegeneration mouse model Pde6b rd1/rd1 , the researchers investigated molecular and cellular events that might initiate and/or trigger rod cell death by applying an integrated multi-omics approach. (nih.gov)
  • Specifically, it is not well understood how dozens of different molecules work together in the crowded cellular environment to regulate and catalyze exocytosis and endocytosis. (nih.gov)
  • It shows Y-Warm material contains nanometer-scale cell walls and independent micrometer-scale foam cells, very like a honeycomb structure. (do-matrix.com)
  • The findings suggest that boosting cellular energy levels could help damaged adult nerve cells repair themselves. (nih.gov)
  • These structures convert energy from food into a form that cells can use. (medlineplus.gov)
  • Expand coverage for cellular services with distributed antenna systems (DAS) and small cells, and deploy private wireless networks for mission-critical applications. (commscope.com)
  • Plants also will come with a secondary mobile structure, a hard, thick coating fashioned inside the original herb cell walls when the cellular try mature. (arafaoasis.com)
  • Recently, cell-free polyadenylation assays suggested that perturbation of the EIAV TAR secondary structure diminished polyadenylation efficiency. (nih.gov)
  • The Cellular Senescence Network (SenNet) program was created to catalyze the development of a framework for mapping cellular senescence and its associated secretory phenotype at high resolution using existing and new tools, to provide comprehensive atlases of cellular senescence in multiple tissues and under diverse conditions, including early development, health, and across the lifespan. (nih.gov)
  • In addition, it is expected that SenNet will provide comprehensive sets of biomarkers describing heterogeneous senescent cell states, as well as additional tools to facilitate the study of cellular senescence at the single cell level. (nih.gov)
  • Cellular structures are regarded as excellent candidates for lightweight-design, load-bearing, and energy-absorbing applications. (techscience.com)
  • Present studies are more mechanistic and seek to understand the pathogenesis of the disease at the cellular and molecular level, identify vaccine candidates, and develop novel therapeutic approaches. (nih.gov)
  • This provides a possibility to observe all of the structures mentioned above, except the tip-links, and their response to acoustic stimulation, while at the same time recording electrophysiological events. (jneurosci.org)
  • Prior to this study, we lacked knowledge of the precise cellular events and molecular cues that precede the onset of pathology. (nih.gov)
  • The experimental model is representative of one cell of a typical multi-cellular structure and the results obtained can be used in the application of grillage techniques to the analysis of such structures. (trb.org)
  • This work presents a methodology for the analysis of the dynamic behavior of periodic cellular structures, which allows the evaluation of location and spectral width of propagation and attenuation regions. (gatech.edu)
  • Cellular structures exhibit a number of desirable multifunctional properties, which make them attractive in a variety of engineering applications. (gatech.edu)
  • They will address the regulation of these cellular functions at three hierarchical tiers: molecular-, cellular- and supracellular levels. (universityofgalway.ie)
  • In this paper, a novel S-based TPMS hollow isotropic cellular structure is proposed with both superior load-bearing and energy-absorbing performances. (techscience.com)
  • The isolated large mammalian brain's capacity for restoration of microcirculatory, molecular and cellular activity has been underappreciated. (nih.gov)
  • Herb cell have original cell wall, that will be an adaptable film designed on the exterior an evergrowing remove cellular. (arafaoasis.com)
  • 1:01:01: How easy is it to introduce structured water into your diet? (apple.com)