Nerve Tissue: Differentiated tissue of the central nervous system composed of NERVE CELLS, fibers, DENDRITES, and specialized supporting cells.Sciatic Nerve: A nerve which originates in the lumbar and sacral spinal cord (L4 to S3) and supplies motor and sensory innervation to the lower extremity. The sciatic nerve, which is the main continuation of the sacral plexus, is the largest nerve in the body. It has two major branches, the TIBIAL NERVE and the PERONEAL NERVE.Peripheral Nerves: The nerves outside of the brain and spinal cord, including the autonomic, cranial, and spinal nerves. Peripheral nerves contain non-neuronal cells and connective tissue as well as axons. The connective tissue layers include, from the outside to the inside, the epineurium, the perineurium, and the endoneurium.Neoplasms, Nerve Tissue: Neoplasms composed of nerve tissue. This concept does not refer to neoplasms located in the nervous system or its component nerves.Portulaca: A plant genus of the family PORTULACACEAE.Nerve Regeneration: Renewal or physiological repair of damaged nerve tissue.Optic Nerve: The 2nd cranial nerve which conveys visual information from the RETINA to the brain. The nerve carries the axons of the RETINAL GANGLION CELLS which sort at the OPTIC CHIASM and continue via the OPTIC TRACTS to the brain. The largest projection is to the lateral geniculate nuclei; other targets include the SUPERIOR COLLICULI and the SUPRACHIASMATIC NUCLEI. Though known as the second cranial nerve, it is considered part of the CENTRAL NERVOUS SYSTEM.Organic Chemistry Phenomena: The conformation, properties, reaction processes, and the properties of the reactions of carbon compounds.PropaneOptical Imaging: The use of light interaction (scattering, absorption, and fluorescence) with biological tissue to obtain morphologically based information. It includes measuring inherent tissue optical properties such as scattering, absorption, and autofluorescence; or optical properties of exogenous targeted fluorescent molecular probes such as those used in optical MOLECULAR IMAGING, or nontargeted optical CONTRAST AGENTS.Nanofibers: Submicron-sized fibers with diameters typically between 50 and 500 nanometers. The very small dimension of these fibers can generate a high surface area to volume ratio, which makes them potential candidates for various biomedical and other applications.Schwann Cells: Neuroglial cells of the peripheral nervous system which form the insulating myelin sheaths of peripheral axons.Nerve Tissue ProteinsTissue Scaffolds: Cell growth support structures composed of BIOCOMPATIBLE MATERIALS. They are specially designed solid support matrices for cell attachment in TISSUE ENGINEERING and GUIDED TISSUE REGENERATION uses.Nerve Fibers: Slender processes of NEURONS, including the AXONS and their glial envelopes (MYELIN SHEATH). Nerve fibers conduct nerve impulses to and from the CENTRAL NERVOUS SYSTEM.Axons: Nerve fibers that are capable of rapidly conducting impulses away from the neuron cell body.Spinal Cord: A cylindrical column of tissue that lies within the vertebral canal. It is composed of WHITE MATTER and GRAY MATTER.Nerve Block: Interruption of NEURAL CONDUCTION in peripheral nerves or nerve trunks by the injection of a local anesthetic agent (e.g., LIDOCAINE; PHENOL; BOTULINUM TOXINS) to manage or treat pain.Nerve Endings: Branch-like terminations of NERVE FIBERS, sensory or motor NEURONS. Endings of sensory neurons are the beginnings of afferent pathway to the CENTRAL NERVOUS SYSTEM. Endings of motor neurons are the terminals of axons at the muscle cells. Nerve endings which release neurotransmitters are called PRESYNAPTIC TERMINALS.Sural Nerve: A branch of the tibial nerve which supplies sensory innervation to parts of the lower leg and foot.Median Nerve: A major nerve of the upper extremity. In humans, the fibers of the median nerve originate in the lower cervical and upper thoracic spinal cord (usually C6 to T1), travel via the brachial plexus, and supply sensory and motor innervation to parts of the forearm and hand.Facial Nerve: The 7th cranial nerve. The facial nerve has two parts, the larger motor root which may be called the facial nerve proper, and the smaller intermediate or sensory root. Together they provide efferent innervation to the muscles of facial expression and to the lacrimal and SALIVARY GLANDS, and convey afferent information for TASTE from the anterior two-thirds of the TONGUE and for TOUCH from the EXTERNAL EAR.Nerve Crush: Treatment of muscles and nerves under pressure as a result of crush injuries.Peripheral Nerve Injuries: Injuries to the PERIPHERAL NERVES.Tibial Nerve: The medial terminal branch of the sciatic nerve. The tibial nerve fibers originate in lumbar and sacral spinal segments (L4 to S2). They supply motor and sensory innervation to parts of the calf and foot.Ulnar Nerve: A major nerve of the upper extremity. In humans, the fibers of the ulnar nerve originate in the lower cervical and upper thoracic spinal cord (usually C7 to T1), travel via the medial cord of the brachial plexus, and supply sensory and motor innervation to parts of the hand and forearm.Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents.Femoral Nerve: A nerve originating in the lumbar spinal cord (usually L2 to L4) and traveling through the lumbar plexus to provide motor innervation to extensors of the thigh and sensory innervation to parts of the thigh, lower leg, and foot, and to the hip and knee joints.Spinal Nerves: The 31 paired peripheral nerves formed by the union of the dorsal and ventral spinal roots from each spinal cord segment. The spinal nerve plexuses and the spinal roots are also included.Nerve Growth Factor: NERVE GROWTH FACTOR is the first of a series of neurotrophic factors that were found to influence the growth and differentiation of sympathetic and sensory neurons. It is comprised of alpha, beta, and gamma subunits. The beta subunit is responsible for its growth stimulating activity.Trigeminal Nerve: The 5th and largest cranial nerve. The trigeminal nerve is a mixed motor and sensory nerve. The larger sensory part forms the ophthalmic, mandibular, and maxillary nerves which carry afferents sensitive to external or internal stimuli from the skin, muscles, and joints of the face and mouth and from the teeth. Most of these fibers originate from cells of the TRIGEMINAL GANGLION and project to the TRIGEMINAL NUCLEUS of the brain stem. The smaller motor part arises from the brain stem trigeminal motor nucleus and innervates the muscles of mastication.Nerve Growth Factors: Factors which enhance the growth potentialities of sensory and sympathetic nerve cells.Neurons: The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.Phrenic Nerve: The motor nerve of the diaphragm. The phrenic nerve fibers originate in the cervical spinal column (mostly C4) and travel through the cervical plexus to the diaphragm.Radial Nerve: A major nerve of the upper extremity. In humans the fibers of the radial nerve originate in the lower cervical and upper thoracic spinal cord (usually C5 to T1), travel via the posterior cord of the brachial plexus, and supply motor innervation to extensor muscles of the arm and cutaneous sensory fibers to extensor regions of the arm and hand.Cranial Nerves: Twelve pairs of nerves that carry general afferent, visceral afferent, special afferent, somatic efferent, and autonomic efferent fibers.Cells, Cultured: Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.Spinal Nerve Roots: Paired bundles of NERVE FIBERS entering and leaving the SPINAL CORD at each segment. The dorsal and ventral nerve roots join to form the mixed segmental spinal nerves. The dorsal roots are generally afferent, formed by the central projections of the spinal (dorsal root) ganglia sensory cells, and the ventral roots are efferent, comprising the axons of spinal motor and PREGANGLIONIC AUTONOMIC FIBERS.Nerve Compression Syndromes: Mechanical compression of nerves or nerve roots from internal or external causes. These may result in a conduction block to nerve impulses (due to MYELIN SHEATH dysfunction) or axonal loss. The nerve and nerve sheath injuries may be caused by ISCHEMIA; INFLAMMATION; or a direct mechanical effect.Ophthalmic Nerve: A sensory branch of the trigeminal (5th cranial) nerve. The ophthalmic nerve carries general afferents from the superficial division of the face including the eyeball, conjunctiva, upper eyelid, upper nose, nasal mucosa, and scalp.Mandibular Nerve: A branch of the trigeminal (5th cranial) nerve. The mandibular nerve carries motor fibers to the muscles of mastication and sensory fibers to the teeth and gingivae, the face in the region of the mandible, and parts of the dura.Cochlear Nerve: The cochlear part of the 8th cranial nerve (VESTIBULOCOCHLEAR NERVE). The cochlear nerve fibers originate from neurons of the SPIRAL GANGLION and project peripherally to cochlear hair cells and centrally to the cochlear nuclei (COCHLEAR NUCLEUS) of the BRAIN STEM. They mediate the sense of hearing.Splanchnic Nerves: The major nerves supplying sympathetic innervation to the abdomen. The greater, lesser, and lowest (or smallest) splanchnic nerves are formed by preganglionic fibers from the spinal cord which pass through the paravertebral ganglia and then to the celiac ganglia and plexuses. The lumbar splanchnic nerves carry fibers which pass through the lumbar paravertebral ganglia to the mesenteric and hypogastric ganglia.Glossopharyngeal Nerve: The 9th cranial nerve. The glossopharyngeal nerve is a mixed motor and sensory nerve; it conveys somatic and autonomic efferents as well as general, special, and visceral afferents. Among the connections are motor fibers to the stylopharyngeus muscle, parasympathetic fibers to the parotid glands, general and taste afferents from the posterior third of the tongue, the nasopharynx, and the palate, and afferents from baroreceptors and CHEMORECEPTOR CELLS of the carotid sinus.Neural Conduction: The propagation of the NERVE IMPULSE along the nerve away from the site of an excitation stimulus.Optic Nerve Injuries: Injuries to the optic nerve induced by a trauma to the face or head. These may occur with closed or penetrating injuries. Relatively minor compression of the superior aspect of orbit may also result in trauma to the optic nerve. Clinical manifestations may include visual loss, PAPILLEDEMA, and an afferent pupillary defect.Optic Nerve Diseases: Conditions which produce injury or dysfunction of the second cranial or optic nerve, which is generally considered a component of the central nervous system. Damage to optic nerve fibers may occur at or near their origin in the retina, at the optic disk, or in the nerve, optic chiasm, optic tract, or lateral geniculate nuclei. Clinical manifestations may include decreased visual acuity and contrast sensitivity, impaired color vision, and an afferent pupillary defect.Thoracic Nerves: The twelve spinal nerves on each side of the thorax. They include eleven INTERCOSTAL NERVES and one subcostal nerve. Both sensory and motor, they supply the muscles and skin of the thoracic and abdominal walls.Nerve Fibers, Myelinated: A class of nerve fibers as defined by their structure, specifically the nerve sheath arrangement. The AXONS of the myelinated nerve fibers are completely encased in a MYELIN SHEATH. They are fibers of relatively large and varied diameters. Their NEURAL CONDUCTION rates are faster than those of the unmyelinated nerve fibers (NERVE FIBERS, UNMYELINATED). Myelinated nerve fibers are present in somatic and autonomic nerves.Accessory Nerve: The 11th cranial nerve which originates from NEURONS in the MEDULLA and in the CERVICAL SPINAL CORD. It has a cranial root, which joins the VAGUS NERVE (10th cranial) and sends motor fibers to the muscles of the LARYNX, and a spinal root, which sends motor fibers to the TRAPEZIUS and the sternocleidomastoid muscles.Facial Nerve Injuries: Traumatic injuries to the facial nerve. This may result in FACIAL PARALYSIS, decreased lacrimation and salivation, and loss of taste sensation in the anterior tongue. The nerve may regenerate and reform its original pattern of innervation, or regenerate aberrantly, resulting in inappropriate lacrimation in response to gustatory stimuli (e.g., "crocodile tears") and other syndromes.Abducens Nerve: The 6th cranial nerve which originates in the ABDUCENS NUCLEUS of the PONS and sends motor fibers to the lateral rectus muscles of the EYE. Damage to the nerve or its nucleus disrupts horizontal eye movement control.Oculomotor Nerve: The 3d cranial nerve. The oculomotor nerve sends motor fibers to the levator muscles of the eyelid and to the superior rectus, inferior rectus, and inferior oblique muscles of the eye. It also sends parasympathetic efferents (via the ciliary ganglion) to the muscles controlling pupillary constriction and accommodation. The motor fibers originate in the oculomotor nuclei of the midbrain.Sympathetic Nervous System: The thoracolumbar division of the autonomic nervous system. Sympathetic preganglionic fibers originate in neurons of the intermediolateral column of the spinal cord and project to the paravertebral and prevertebral ganglia, which in turn project to target organs. The sympathetic nervous system mediates the body's response to stressful situations, i.e., the fight or flight reactions. It often acts reciprocally to the parasympathetic system.Cranial Nerve Neoplasms: Benign and malignant neoplasms that arise from one or more of the twelve cranial nerves.Facial Nerve Diseases: Diseases of the facial nerve or nuclei. Pontine disorders may affect the facial nuclei or nerve fascicle. The nerve may be involved intracranially, along its course through the petrous portion of the temporal bone, or along its extracranial course. Clinical manifestations include facial muscle weakness, loss of taste from the anterior tongue, hyperacusis, and decreased lacrimation.
Loose connective tissue. Loose connective tissue contains fibres, extracellular matrix, cells, nerves and blood vessels. ... The cells include fibroblast, defence cells and undifferentiated mesenchymal cells. Cell Rest of Malassez. These groups ... The PDL consists of principal fibres, loose connective tissue, blast and clast cells, oxytalan fibres and Cell Rest of Malassez ... The tissues of the periodontium combine to form an active, dynamic group of tissues. The alveolar bone (C) is surrounded for ...
Models: Tissue cultures of dissociated nerve cells. Spinal cord of the rat. Neuromuscular junction of the rat, mouse and frog. ... Molecular mechanisms of chemical interaction between excitable cells and factors determining excitability of nerve cells and ... 47:291-5, 1998, BBA 2008 etc). 3. Ion-selective microelectrodes for K+ and Na+ in nerve and muscle tissue. He performed first ... 2009, etc.). 6. Patch-clamp studies on nerve and muscle cells. First demonstration of K+ channel subtypes during myotube ...
Each nerve lies within a cord of connective tissue lying beneath the cuticle and between the muscle cells. The ventral nerve is ... At the anterior end of the animal, the nerves branch from a dense, circular nerve (nerve ring) round surrounding the pharynx, ... Behind the sensory bristles on the head lie two small pits, or 'amphids'. These are well supplied with nerve cells, and are ... Projections run from the inner surface of muscle cells towards the nerve cords; this is a unique arrangement in the animal ...
More recently, it is becoming clear what types of nerves innervated which sections of bone. The periosteal layer of bone tissue ... Bone tumors are composed of a conglomeration of cell types including cancer and immune system cells. Often tumor cells secrete ... Stimulation of specialized pain-sensitive nerve fibers (nociceptors) that innervate bone tissue leads to the sensation of bone ... Metastatic cancer cells often establish themselves within the skeleton. When the cancer cells have metastasized, the mechanical ...
Regeneration in humans
The nerves in the spine are a tissue that requires a stem cell population to regenerate. In 2012 a Polish fireman Darek Fidyka ... In humans with non-injured tissues, the tissue is naturally regenerated over time; by default these tissues have new cells ... 2014). "Humans iPS cell-engineered cardiac tissue sheets with cardiomyocytes and vascular cells for cardiac regeneration". ... nerve and pancreas, as these tissue types need stem cell populations. The first organ ever induced and made in the lab was the ...
2016 in science
21 November - Researchers use human pluripotent stem cells to grow human intestinal tissues with functioning nerves, then use ... One of the most flexible types of stem cell, these can develop into all human tissue other than the placenta. 7 March - German ... Researchers at Rutgers and Stanford universities develop a novel way to inject healthy human nerve cells into mouse brains, ... "Scientists Tissue Engineer Human Intestines and Functioning Nerves". Cincinnati Children's Hospital Medical Center. 21 November ...
Toxic effects from anatoxin-a progress very rapidly because it acts directly on the nerve cells (neurons) as a neurotoxin. The ... The nerve tissues which communicate with muscles contain a receptor called the nicotinic acetylcholine receptor. Stimulation of ... It acts on the voltage-gated sodium channels of nerve cells, preventing normal cellular function and leading to paralysis. The ... Nerve synapse Anabaena, Aphanizomenon, Lyngbya, Cylindrospermopsis Lipopolysaccharides Potential irritant; affects any exposed ...
It consists of loose connective tissue, adipose tissue and elastin. The main cell types are fibroblasts, macrophages and ... Sensation: contains a variety of nerve endings that react to heat and cold, touch, pressure, vibration, and tissue injury; see ... Cells are formed through mitosis at the basale layer. The daughter cells (see cell division) move up the strata changing shape ... The main type of cells that make up the epidermis are Merkel cells, keratinocytes, with melanocytes and Langerhans cells also ...
Friedrich Gustav Jakob Henle
This causes calcification of tissue and loss of nerve cells in the cerebral cortex. Neurological symptoms include seizures that ... In babies with SWS due to mutation of gene GNAQ, this network of nerves doesn't go away. This reduces the amount of oxygen and ... Around the sixth week of development, a network of nerves develops around the area that will become a baby's head. Normally, ... blood flowing to the brain, which can affect brain tissue development. CT and MRI are most often used to identify intracranial ...
Normal peristalsis depends upon the interaction between muscles, nerve cells and tendinous connective tissue. A malfunction of ... Intestinal Connective tissue abnormality may cause Intestinal Desmosis The absence of the tendinous plexus layer was first ... Histological findings are absence of the tendinous plexus layer and connective tissue fibers in longitudinal and circular ... Inflammation of the muscularis propria releases enzymes including collagenases which destroy the connective tissue of the bowel ...
The body tissues are composed of numerous types of cell, including those found in muscles, nerves and skin. Each typically has ... Metazoans do not include the sponges, which have undifferentiated cells. Unlike plant cells, animal cells have neither a cell ... The outer epithelial layer may include cells of several types including sensory cells, gland cells and stinging cells. There ... Nervous tissue is composed of many nerve cells known as neurons which transmit information. In some slow-moving radially ...
Cell type. The cells that interpret information about the environment can be either (1) a neuron that has a free nerve ... Nociception (physiological pain) signals nerve-damage or damage to tissue. The three types of pain receptors are cutaneous ( ... Every nerve, sensory or motor, has its own signal transmission speed. For example, nerves in the frog's legs have a 90 ft/s (99 ... Via cranial and spinal nerves, the different types of sensory receptor cells (mechanoreceptors, photoreceptors, chemoreceptors ...
Cranial neural crest
"Improvement of peripheral nerve regeneration by a tissue-engineered nerve filled with ectomesenchymal stem cells". Int J Oral ... nerves and connective tissue. The endocranium and facial bones of the skull are ultimately derived from crest cells. Other ... Sensory ganglia of the fifth, seventh, ninth and tenth cranial nerves. Schwann cells "The Neural Crest". Retrieved 2009-05-31. ... Jiang HB, Tian WD, Liu LK, Xu Y (June 2008). "In vitro odontoblast-like cell differentiation of cranial neural crest cells ...
Once released (lysed), and ingested, these toxins can damage liver and nerve tissues in mammals. In areas where water quality ... Effects of the Blue Green Algae Aphanizomenon flos-aquae on Human Natural Killer Cells. - Chapter 3.1 of the IBC Library Series ... Aphanizomenon flos-aquae is known to produce endotoxins, the toxic chemicals released when cells die. ... found that eating it had a profound effect on natural killer cells (NKCs). A. flos-aquae triggers the movement of 40% of the ...
The nerve tissues which communicate with muscles contain a receptor called the nicotinic acetylcholine receptor. Stimulation of ... Toxic effects from anatoxin-a progress very rapidly because it acts directly on the nerve cells (neurons). The progressive ... Neurotoxins are toxins that are poisonous or destructive to nerve tissue (causing neurotoxicity). Neurotoxins are an extensive ... which would induce significant neuron death if they reach nervous tissue. Thus, protective cells termed astrocytes surround the ...
It is responsible for preparing the tissue for repair and promoting recruitment of certain cells to the wound area. ... The ANS directly innervates tissue through the postganglionic nerves, which is controlled by preganglionic neurons originating ... This type of stress saw in increase in granulocytes, natural killer cells, IgA, Interleukin 6, and an increase in cell ... Brief naturalistic stressors elicit a shift from Th1(cellular) to Th2(humoral) immunity, while decreased T-cell proliferation, ...
The growth of cervical loop cells into the deeper tissues forms Hertwig's Epithelial Root Sheath, which determines a tooth's ... This tissue contains blood vessels and nerves that enter the tooth from a hole at the apex of the root. Along the border ... The dental papilla contains cells that develop into odontoblasts, which are dentin-forming cells. Additionally, the ... It is one of the four major tissues which make up the tooth, along with dentin, cementum, and dental pulp. It is normally ...
Irritation to the nerve can also come from inflammation to the tissue. Joint conditions such as rheumatoid arthritis, psoriatic ... Without a proper supply of blood and nutrients, nerve cells can no longer adequately send signals to the brain. Because of this ... Similar brief shocks can be experienced when any other nerve is tweaked (a tweaked neck nerve may cause a brief shock-like ... also notably may cause recurring pain and tingling in skin or tissue along the distribution path of that nerve (most commonly ...
Ectomesenchymal chondromyxoid tumor
The cells may extend into and entrap soft tissue structures including skeletal muscle and nerve bundles. The tumor is made up ... Sometimes large cells are seen in chondroid or cartilaginous areas. Swirling formations give the appearance of neural tissue. ... often separated from the periphery and internally by fibrous connective tissue bands. The cells are arranged in cords, nests, ... mesenchymal cells. There are some who think it is a myoepithelial tumor type. Derived from ectomesenchymal cells migrating from ...
Neural Regeneration Research
As opposed to osseous tissue, the periosteum has nociceptive nerve endings, making it very sensitive to manipulation. It also ... After a bone fracture the progenitor cells develop into osteoblasts and chondroblasts, which are essential to the healing ... The periosteum consists of dense irregular connective tissue. It is divided into an outer "fibrous layer" and inner "cambium ... layer" (or "osteogenic layer"). The fibrous layer contains fibroblasts, while the cambium layer contains progenitor cells that ...
Face and neck development of the human embryo
In addition, the muscular components of each arch have their own cranial nerve, and wherever the muscle cells migrate, they ... Initially, pharyngeal grooves consist of four bars of mesenchymal tissue that separate pharyngeal nerves. Most of these ... The corresponding nerve for the three prominences of the anterior tongue is the trigeminal nerve. The posterior tongue is ... It is derived from neural crest cells, which have an ectodermal origin. These neural crest cells migrate from the ectoderm as ...
Creatine and its phosphorylated form play a central role in the energy metabolism of muscle and nerve tissues. Creatine is in ... Creatine helps buffer the rapid changes in ADP/ATP ratio in muscle and nerve cells during active periods. Creatine is also ... of the cells that make up those tissues. L-Arginine:glycine amidinotransferase catalyses the first, which is also the committed ... It has been suggested that AGAT activity in tissues is regulated in a number of ways including induction by growth hormone and ...
Francis, a physiologist, was studying "the molecular organization of cells and tissues with particular reference to nerve ... After his time at Woods Hole, Otto and his wife Viola moved to London to continue his research with nerve impulses under ... "the brothers were eager to go there together to use Otto's new electrical apparatus on the unusually large nerve axons of squid ... Otto continued his investigation into nerve impulse formation and propagation. He also looked for new applications for his war ...
Enamel is not a vital tissue, as it lacks blood vessels, nerves, and living cells. Consequently, pathologic processes involving ... and an inner soft tissue core (the pulp system), which contains nerves and blood vessels. The visible parts of the teeth in the ... infarcts in the jaws caused by sickle cell disease, and osteomyelitis. Various conditions of the trigeminal nerve can ... and unmyelinated C nerve fibers (slow, dull, aching, or burning pain) of the trigeminal nerve, which supplies sensation to the ...
Encephalopsins and neuropsins are highly expressed in nerve cells and brain tissue, but so far their function is unknown. ... of the rod cells in the vertebrate retina absorbs green-blue light. The photopsins of the cone cells of the retina differ in a ... This change acts as a molecular switch to activate a signal transduction mechanism within the cell. Depending on the type of ... They are commonly found in the light-sensing organs, for example in the photoreceptor cells of vertebrate retina where they ...
Type 2 diabetes
... a type 2 diabetic will have lost about half of their beta cells. Fatty acids in the beta cells activate FOXO1, resulting in ... and fat tissue. In the liver, insulin normally suppresses glucose release. However, in the setting of insulin resistance, ... Type 2 diabetes is due to insufficient insulin production from beta cells in the setting of insulin resistance. Insulin ... In the early stages of insulin resistance, the mass of beta cells expands, increasing the output of insulin to compensate for ...
A CT scan can distinguish muscle tissue from other tissues and thereby estimate the amount of muscle tissue in the body. Fast ... Neurogenic atrophy, which has a similar effect, is muscle atrophy resulting from damage to the nerve which stimulates the ... "satellite cells" which help to regenerate skeletal muscle fibers, and a decrease in sensitivity to or the availability of ... Disuse of the muscles, such as when muscle tissue is immobilized for even a few days of unuse - when the patient has a primary ...
The TH2 lymphocytes interact with B cells and together they produce IgE. IgE circulates around and binds to receptors of cells ... For example, after a back surgery that removed a herniated disc from causing a pinched nerve, the patient may still continue to ... In "central sensitization," nociceptive neurons in the dorsal horns of the spinal cord become sensitized by peripheral tissue ... the Antigen-Presenting Cell causes a response in a TH2 lymphocyte which produce the cytokine interleukin-4 (IL-4). ...
The epidermis tissue includes several differentiated cell types; epidermal cells, epidermal hair cells (trichomes), cells in ... 2 major basal nerves besides the midrib. Diagrams of venation patternsEdit. ... Esau, Katherine (2006) . Evert, Ray F (ed.). Esau's Plant Anatomy: Meristems, Cells, and Tissues of the Plant Body: Their ... Cells that bring water and minerals from the roots into the leaf.. Phloem. Cells that usually move sap, with dissolved sucrose( ...
... stem cells, white blood cells) in many tissues and organs. SP amplifies or excites most cellular processes. ... When the innervation to substance P nerve terminals is lost, post-synaptic cells compensate for the loss of adequate ... Cell growth, proliferation, angiogenesis, and migrationEdit. The above processes are part and parcel to tissue integrity and ... Elevation of serum, plasma, or tissue SP and/or its receptor (NK1R) has been associated with many diseases: sickle cell crisis; ...
The skin consists of a thin outer epidermis with mucous cells and sensory cells, and a connective tissue dermis consisting ... It contains tetrodotoxin, which causes paralysis by blocking the transmission of nerve impulses to the muscles. This causes ... Other colour-changing cells are reflective iridophores and white leucophores. This colour-changing ability is also used to ... largely of collagen fibres and various cells allowing colour change. Most of the body is made of soft tissue allowing it to ...
The use of a transcutaneous electrical nerve stimulation device has been shown to alleviate hyperalgesia. ... This seems to occur via immune cells interacting with the peripheral nervous system and releasing pain-producing chemicals ( ... Secondary hyperalgesia describes pain sensitivity that occurs in surrounding undamaged tissues.. Opioid-induced hyperalgesia ... Hyperalgesia is similar to other sorts of pain associated with nerve irritation or damage such as allodynia and neuropathic ...
Neurological (consciousness, awareness, brain, vision, cranial nerves, spinal cord and peripheral nerves) ... Histology is the study of the structures of biological tissues by light microscopy, electron microscopy and ... discovered by Paul Ehrlich in 1908 after he observed that bacteria took up toxic dyes that human cells did not. The first major ... Subspecialties include electroencephalography, electromyography, evoked potential, nerve conduction study and polysomnography. ...
Category:Mid-importance Anatomy articles
The cells of connective tissue include fibroblasts, adipocytes, macrophages, mast cells and leucocytes. ... Connective tissue neoplasms including sarcomas such as hemangiopericytoma and malignant peripheral nerve sheath tumor in ... Connective tissue (CT) is one of the four basic types of animal tissue, along with epithelial tissue, muscle tissue, and ... and special connective tissue. Connective tissue proper consists of loose connective tissue and dense connective tissue ( ...
... leading to a buildup of dead tissue, cell debris and toxins at or near the site of the necrotic cells ... Optic nerve sheath meningioma, Pediatric ependymoma, Pilocytic astrocytoma, Pinealoblastoma, Pineocytoma, Pleomorphic ... Anaplastic cells have lost total control of their normal functions and many have deteriorated cell structures. Anaplastic cells ... The thalamus and hypothalamus of the diencephalon also consist of neuron and glial cell tissue with the hypophysis (pituitary ...
NervesEdit. The reptilian nervous system contains the same basic part of the amphibian brain, but the reptile cerebrum and ... Morphological and cellular aspects of tail and limb regeneration in lizards a model system with implications for tissue ... Cell. 25 (4): 326-328. doi:10.1016/j.devcel.2013.05.011. PMID 23725759.. ... via connective tissue) to the rest of the viscera. By using a series of special muscles (roughly equivalent to a diaphragm), ...
Soft tissue laceration. Facial nerve branches. Facial nerve should be examined for any potential damage when buccal ... as this will damage the delicate cells that make up the tooth's interior. ... The layers of tissue that make up the tooth are clearly visible, with the pink pulp standing out against the paler dentine and ... The facial nerve and parotid duct should be examined for any potential damage when the buccal mucosa is involved. ...
Cortisol is a major stress hormone and has effects on many tissues in the body, including the brain. In the brain, cortisol ... CRH and vasopressin are released from neurosecretory nerve terminals at the median eminence. CRH is transported to the anterior ... There, CRH and vasopressin act synergistically to stimulate the secretion of stored ACTH from corticotrope cells. ACTH is ... This helps to protect the organism from a lethal overactivation of the immune system, and minimizes tissue damage from ...
Efferent nerve fibers of gamma motoneurons also terminate in muscle spindles; they make synapses at either or both of the ends ... Muscle spindles have a capsule of connective tissue, and run parallel to the extrafusal muscle fibers.[c] ... They convey length information to the central nervous system via afferent nerve fibers. This information can be processed by ... Muscle Nerve. 31 (2): 135-56. CiteSeerX 10.1.1.126.3583. doi:10.1002/mus.20261. PMID 15736297.. ...
Hyperimmunoglobulin E syndrome
Azari kept all the nerves and tendons long and extended, which would give him plenty to work with later. Then he sutured them ... 2008). "Hand Transplantation: The Innsbruck Experience". Transplantation of Composite Tissue Allografts. pp. 234-250. doi: ... The recipient's hand was removed during the same 8 hour operation, reportedly allowing very accurate restoration of nerve ... July 2007). "Second report (1998-2006) of the International Registry of Hand and Composite Tissue Transplantation". Transpl ...
Death of Caylee Anthony
However, he told the defense he did not know that George had a second cell phone. ... "struck such a nerve" with the public. "I think when people see someone that they believe has so gone away from [a mother's love ... Investigative teams recovered duct tape which was hanging from Caylee's hair and some tissue left on her skull. Over the ...
Diabetic ketoacidosis - Simple English Wikipedia, the free encyclopedia
Without enough electrolytes, the heart, muscles, and nerve cells cannot work properly. Also, eventually, the kidneys can fail ... This causes the tissues in the body to lose nitrogen. ... If the cells give up too much water, they can get dehydrated ( ... The cells start starving, because they do not have insulin to break down glucose into a form that the cells can use for energy ... In homeostasis, there would be an equal amount of sugar in the bloodstream and the cells. To try to make this happen, the cells ...
කොලෙස්ටරෝල් - විකිපීඩියා, නිදහස් විශ්වකෝෂය
Cholesterol is primarily synthesized from acetyl CoA through the HMG-CoA reductase pathway in many cells and tissues. About 20- ... In myelin, it envelopes and insulates nerves, helping greatly to conduct nerve impulses. ... Low-density lipoproteins are taken into the cell by LDL receptor-mediated endocytosis in clathrin-coated pits, and then ... It plays a central role in many biochemical processes, such as the building of cell membranes and the synthesis of steroid ...
Fruit and vegetables for kids
Vitamin A assists in the maintenance and promotion of healthy growth of skin and tissues cells. Healthy growth of tissue cells ... Assists in functionality of muscle construction and nerve impulses - Calcium regulates the transmutation of nerve impulses for ... Zinc ensure the body has healthy growth by influencing cell division and cell growth. Development of chronic disease has become ... Maintains mucous cell tissues to ensure a secure barrier against harmful bacteria's and disease (Deen & Hark, 2007) Helps ...
Evert RF, Eichhorn SE (2006). Esau's Plant Anatomy: Meristems, Cells, and Tissues of the Plant Body: Their Structure, Function ... Deficiency of plasmalogens causes profound abnormalities in the myelination of nerve cells, which is one reason why many ... when excess H2O2 accumulates in the cell, catalase converts it to H2O through this reaction: 2. H. 2. O. 2. →. 2. H. 2. O. +. O ... "The Journal of Cell Biology. 119 (5): 1129-36. doi:10.1083/jcb.119.5.1129. PMC 2289717. PMID 1447292.. ...
Intravenous regional anesthesia
For example, benzodiazepine and fentanyl are often added to prevent seizures and to improve nerve blockage, respectively. ... The anesthetic agent is intravenously introduced into the limb and allowed to diffuse into the surrounding tissue while ... such as in sickle cell anemia, where there is a risk of massive hemolysis due to low oxygen tension or hemolytic crisis due to ... The veins are filled with the anesthetic, with the anesthetic setting into local tissue after approximately 6-8 minutes, after ...
Schizophrenia - Simple English Wikipedia, the free encyclopedia
... brain tissue development was replicated in three dimensions by scientists cloning a human "mini-brain" using stem cells. This ... the band of nerve fibers which connects the left side and the right side of the brain. People with schizophrenia also tend to ... but clozapine can lower the white blood cell count in 1 to 4 percent of people who take it. This is a serious side effect.[ ...
Brain-derived neurotrophic factor
nerve development. • nerve growth factor signaling pathway. • regulation of neuron differentiation. • neuron projection ... cell-cell signaling. • positive regulation of brain-derived neurotrophic factor receptor signaling pathway. • collateral ... Although BDNF is needed in the developmental stages, BDNF levels have been shown to decrease in tissues with aging. Studies ... regulation of protein localization to cell surface. • regulation of receptor activity. • activation of phospholipase C activity ...
The cancerous tissue is removed and the incision is closed. Post operative care may employ the use of suction drainage to ... The surgeon cuts the shaft of the elongated phallus and sews the glans and preserved nerves back onto the stump. In a less ... If the malignancy is present in muscular tissue in the region, it is also removed. In some cases, the surgeon is able to ... allow the deeper tissues to heal toward the surface. Follow up after surgery includes the stripping of the drainage device to ...
Cell biologyEdit. Main article: Biomarker (cell). In cell biology, a biomarker is a molecule that allows the detection and ... These include dendritic protein microtubule-associated protein-2 (MAP-2) [137,138], brain-derived nerve growth factor (BDNF) [ ... and interdependent cascades of biological reactions at the tissue, cellular, and subcellular levels. Due to the extended length ... Basu, P. K.; Miller, I.; Ormsby, H. L. (1960-03-01). "Sex chromatin as a biologic cell marker in the study of the fate of ...
Cell death may be instigated in the meibomian glands, hypothalamic cells, hippocampus cells and-important ... The influence of isotretinoin and 5-a reductase inhibitors in metaloproteases of connective tissue in patients with ance] (in ... It is also used for treatment of neuroblastoma, a form of nerve cancer. ... programmatic cell death) in various cells in the body. ... suppresses hippocampal cell survival in mice". Annals of the ...
Using Stem Cells to Grow Artificial Tissue for Peripheral Nerve Repair
... and clinical studies in all areas of stem cell biology and applications. The journal will consider basic, translational, and ... Stem Cells International is a peer-reviewed, Open Access journal that publishes original research articles, review articles, ... Currently, there are no licensed stem cell based artificial nerve tissues for peripheral nerve repair. Using stem cells in ... "Adipose derived stem cells" (. ), "Dental pulp stem cells" (. ), "Neural stem cells" (. ), "Skin derived stem cells" (. ), " ...
Stem Cells and Nerves Interact in Tissue Regeneration and Cancer Progression
Regeneration »bone marrow stem cells »cancer progression »cancer stem cells »cell types »nerves »neurons »stem cells »tissue ... cancer stem cells , cell types , nerves , neurons , stem cells , tissue regeneration ... Cancer cells (green) are innervated with nerve cells (red). The cell nuclei (blue) are also visible. ... Im Focus: Stem Cells and Nerves Interact in Tissue Regeneration and Cancer Progression. Researchers at the University of Zurich ...
Scientists produce functional intestine. Tissue, nerves and muscles from a single line of human stem cells | Bioethics Research...
... they recently reported in Nature Medicine that they had grown a piece of gut-nerves, muscles and all& ... ... In 2011 researchers at the same center announced that they had grown intestinal tissue-but it was missing nerve cells and so ... Tissue, nerves and muscles from a single line of human stem cells. ... "Just like in developing human bodies, the nerve cells knew where to go," says Michael Helmrath, surgical director of the ...
Dedifferentiation, redifferentiation and bundle formation of smooth muscle cells in tissue culture: the influence of cell...
... redifferentiation and bundle formation of smooth muscle cells in tissue culture: the influence of cell number and nerve fibres ... redifferentiation and bundle formation of smooth muscle cells in tissue culture: the influence of cell number and nerve fibres ... redifferentiation and bundle formation of smooth muscle cells in tissue culture: the influence of cell number and nerve fibres ... redifferentiation and bundle formation of smooth muscle cells in tissue culture: the influence of cell number and nerve fibres ...
Stem Cells and Nerves Interact in Tissue Regeneration and Cancer Progression | myScience / news / news 2020
Innervation may therefore be crucial for proper tissue regeneration. They also demonstrate that cancer stem cells likewise ... Researchers at the University of Zurich show that different stem cell populations are innervated in distinct ways. ... establish contacts with nerves. Targeting tumour innervation could thus lead to new cancer therapies. ... Cancer cells (green) are innervated with nerve cells (red). The cell nuclei (blue) are also visible. (Image: Institute of Oral ...
A New Method for Staining Connective Tissue Fibres, with a Note on Liang's Method for Nerve-fibres | Journal of Cell Science
A New Method for Staining Connective Tissue Fibres, with a Note on Liangs Method for Nerve-fibres ... A New Method for Staining Connective Tissue Fibres, with a Note on Liangs Method for Nerve-fibres ... A New Method for Staining Connective Tissue Fibres, with a Note on Liangs Method for Nerve-fibres ... A New Method for Staining Connective Tissue Fibres, with a Note on Liangs Method for Nerve-fibres ...
KAKEN - Research Projects | Establishment of transplantation methods by using neural stem cells and peripheral nerve tissues...
Establishment of transplantation methods by using neural stem cells and peripheral nerve tissues for spinal cord repair. ... A combination of hippocampus-derived NSC and peripheral nerves as scaffolds of the cells could be effective treatment to ... neural stem cell / peripheral nerve / transplantation / spinal cord regeneration / 細胞移動 / オリゴ・デンドロサイト. ... In contrast, only 64% of total spinal cord cells were in the dorsal white matter. Both NSC-like cells showed restricted ...
Electrical stimulation of nerve cells using conductive nanofibrous scaffolds for nerve tissue engineering | [email protected]
Electrical stimulation of nerve cells using conductive nanofibrous scaffolds for nerve tissue engineering. Tissue Engineering ... Electrical stimulation of nerve cells using conductive nanofibrous scaffolds for nerve tissue engineering. ... and electrical properties is critical for the success of nerve tissue engineering. Electrical stimulation was directly applied ... stimulation for its enhanced conductivity and is used for in vitro culture and electrical stimulation of nerve stem cells. 3-(4 ...
Interaction of Schwann cells with laminin encapsulated PLCL core-shell nanofibers for nerve tissue engineering | [email protected]
Interaction of Schwann cells with laminin encapsulated PLCL core-shell nanofibers for nerve tissue engineering. ... Laminin is a glycoprotein naturally occurring in nerves and it plays a significant role towards the migration of nerve cells ... Interaction of Schwann cells with laminin encapsulated PLCL core-shell nanofibers for nerve tissue engineering. European ... Nerve tissue engineering (TE) is a rapidly expanding area of research advancing towards the repair and regeneration of non- ...
Joining microelectronics and microionics: Nerve cells and brain tissue on semiconductor chips :: MPG.PuRe
Adult Rat or Mouse Sciatic Nerve: Fresh tissue suspended in media, not frozen cells - Science Exchange
Fresh tissue suspended in media, not frozen cells - Science Exchange Lets You Compare Quotes From Leading Service Providers. ... For more results try searching for Adult Rat or Mouse Sciatic Nerve: Fresh tissue suspended in media, not frozen cells across ... No results found for Adult Rat or Mouse Sciatic Nerve: Fresh tissue suspended in media, not frozen cells ...
Expressed sequence tag analysis of adult human optic nerve for NEIBank: Identification of cell type and tissue markers | BMC...
The data provide clues for tissue-specific and species-specific properties of human ON that will help in design of therapeutic ... We examined the gene expression profile of human optic nerve (ON) and, through the NEIBANK online resource, to provide a ... An un-normalized cDNA library was constructed from pooled human ON tissues and was used in expressed sequence tag (EST) ... Immunofluorescence revealed that this protein is a useful oligodendrocyte cell-type marker in rodent and primate ONs. L-type ...
Re-evaluating microglia expression profiles using RiboTag and cell isolation strategies | Nature Immunology
... which avoids cell retrieval from tissue context and yields translatome sequencing information. Conventional whole-cell ... Isolating tissue-resident cells runs the risk of altering their expression profile. Jung and colleagues use a RiboTagging ... Focusing on microglia, the brains macrophages, we report here a side-by-side comparison of classical cell-sorting-based ... Transcriptome profiling is widely used to infer functional states of specific cell types, as well as their responses to stimuli ...
NIOSHTIC-2 Publications Search - 20042864 - Nerve growth factor reduces amiloride-sensitive Na+ transport in human airway...
Optimum airway surface liquid (ASL), controlled by epithelial cells, is essential for normal lung function. NGF has been shown ... but no information is available as to the effect NGF has on ion transport of airway epithelial cells. T ... Nerve growth factor (NGF) is over-expressed in patients with lung inflammatory diseases including airway virus infections. ... Nerve-function; Nerve-tissue; Nerves; Lung; Lung-disease; Lung-disorders; Viral-diseases; Diseases; Humans; Men; Women ...
Cell-mediated demyelination of peripheral nerve in tissue culture. | Profiles RNS
Cultured Stem Cells Reconstruct Sensory Nerve and Tissue Structure in the Nose | Science and Technology Research News
Cultured Stem Cells Reconstruct Sensory Nerve and Tissue Structure in the Nose. Lab-grown olfactory stem cells will enable ... Home Human Health Cultured Stem Cells Reconstruct Sensory Nerve and Tissue Structure in the Nose ... OE tissue contains two types of stem cells - globose basal cells (GBCs) and HBCs. The GBCs have been successfully cultured and ... The stem cells, called horizontal basal cells (HBCs), can repopulate all olfactory epithelium (OE) cell types, including ...
Patent US6179803 - Cell necrosis apparatus - Google Patents
... energy to the selected tissue site and reduce a volume of the selected site without damaging a hypoglossal nerve. A cable means ... deliver electromagnetic energy to the tissue site and create controlled cell necrosis. The creation of cell necrosis zones 28 ... advance a sufficient distance to a tissue site, deliver electromagnetic energy to the tissue site, create controlled cell ... The creation of cell necrosis zones 28 repositions soft palate structure 94 and tightens the interior tissue of soft palate ...
Scientists find new source of stem cells - latimes
... nerve cells and other kinds of tissue, according to a study published Wednesday in the online edition of ... Scientists have converted cells from human testes into stem cells that grew into muscle, ... Scientists have converted cells from human testes into stem cells that grew into muscle, nerve cells and other kinds of tissue ... Using the testicular cells of adult men, researchers have produced muscle, nerve and other kinds of tissue. ...
Reduced Intensity Stem Cell Transplantation in Children With Relapsed Neuroblastoma After Autologous Transplantation - Full...
Reduced Intensity Stem Cell Transplantation in Children With Relapsed Neuroblastoma After Autologous Transplantation. This ... Neoplasms, Germ Cell and Embryonal. Neoplasms by Histologic Type. Neoplasms. Neoplasms, Glandular and Epithelial. Neoplasms, ... Allogeneic Hematopoietic Stem Cell Transplantation With Reduced-intensity Conditioning in Children With Neuroblastoma Who Have ... In this context, allogeneic stem cell transplantation (allo-SCT) has been tried as salvage treatment in patients with NB who ...
Prominent decline of newborn cell proliferation, differentiation, and apoptosis in the aging dentate gyrus, in absence of an...
In this study, we examined apoptosis, proliferation, migration, and survival of newborn cells in the youn … ... Stem Cells / cytology * Stem Cells / physiology * Stress, Physiological / metabolism Substances * Biomarkers * Nerve Tissue ... We also measured dentate volume and cell numbers, along with basal corticosterone and stress response parameters. We show that ... In this study, we examined apoptosis, proliferation, migration, and survival of newborn cells in the young (2 weeks), young- ...
The Role of Peptide-loaded Dendritic Cells to Augment the Therapeutic Effect of Interleukin-2 - Full Text View - ClinicalTrials...
Neoplasms, Germ Cell and Embryonal. Neoplasms by Histologic Type. Neoplasms. Neoplasms, Nerve Tissue. Nevi and Melanomas. ... The Role of Peptide-loaded Dendritic Cells to Augment the Therapeutic Effect of Interleukin-2. The safety and scientific ... The principal objective of the study is to identify whether a dendritic cell-based vaccine can increase the moderate ... The Role of Autologous Dendritic Cells Pulsed by Melanoma Associated Peptides to Augment the Therapeutic Effect of Interleukin- ...
Cabozantinib in Recurrent/Metastatic Merkel Cell Carcinoma - Full Text View - ClinicalTrials.gov
Expression of c-MET, phospho-MET and VEGFR-2 on tumor tissue [ Time Frame: 2 Years ]. To retrospectively correlate the ... Cabozantinib in Recurrent/Metastatic Merkel Cell Carcinoma. The safety and scientific validity of this study is the ... Carcinoma, Merkel Cell. Carcinoma. Skin Neoplasms. Neoplasms, Glandular and Epithelial. Neoplasms by Histologic Type. Neoplasms ... Must have histologically or cytologically confirmed Merkel Cell Carcinoma that is metastatic or unresectable and for which ...
Expanded Natural Killer Cell Infusion in Treating Younger Patients With Recurrent/Refractory Brain Tumors - Full Text View -...
Function of NK cells [ Time Frame: Up to 30 days after the last infusion in course 3 ]. Assessed by cell lysis of standardized ... Infusing a particular type of a patients own white blood cells called natural killer cells that have been through a procedure ... To determine the persistence of adoptively-transferred expanded NK cells (as performed with excess NK cells, via optional ... Biological: Natural Killer Cell Therapy Given autologous ex-vivo expanded NK cells IV ...
Germline mutations in glial cell line-derived neurotrophic factor (GDNF) and RET in a Hirschsprung disease patient
Glial Cell Line-Derived Neurotrophic Factor Receptors * Nerve Growth Factors * Nerve Tissue Proteins ... The glial cell line-derived neurotrophic factor (GDNF) is such a molecule. Recently, mice carrying two null alleles for Gdnf ... Germline mutations in glial cell line-derived neurotrophic factor (GDNF) and RET in a Hirschsprung disease patient Nat Genet. ...
Cartilage News, Research - Page 3
Stem cells establish contacts with nerves in tissue regeneration and cancer progression Researchers at the University of Zurich ... Old human cells regain youthful strength after rejuvenating protein treatment, study finds Old human cells return to a more ... New 3D model shows how breast cancer cells interact with the bodys stem cells A Loughborough University Ph.D. student has ... 3D-printed tissue-engineering scaffolds with living cells to help heal injuries. ...
Recent Articles | Synthetic Biology And Cell & Molecular Biology | The Scientist Magazine®| Page 11
Scientists Grow Intestinal Tissues With Functional Nerves In The Lab. By Joshua A. Krisch , November 23, 2016 ... Researchers are using the tissue, synthesized with human pluripotent stem cells and implanted into mice, to study a rare form ... Solving a long-standing structural puzzle will open the door to understanding one of the cells most enigmatic machines. ... Profilee Satyajit Mayor discusses his explorations of cell membranes, which are helping to update the classical fluid mosaic ...
Marios G. and Issue - Free people check - Yasni.com
Tissue Engineering of the Peripheral Nerve: Stem Cells and.... books.google.de ... of International Review of Neurobiology brings together cutting-edge research on tissue engineering of the peripheral nerve. It ... The Role of Erythropoietin as an Inhibitor of Tissue Ischemia . Nikolaos Paschos, Marios G. Lykissas ... ... The Role of Erythropoietin as an Inhibitor of Tissue Ischemia. www.ijbs.com ...
Neuroblastoma | NB | MedlinePlus
Neuroblastoma is a cancer in nerve tissue in the adrenal gland, neck, chest, or spinal cord. It often affects young children. ... Neuroblasts are immature nerve tissue. They normally turn into working nerve cells. But in neuroblastoma, they form a tumor. ... This kills the cancer cells, but it also kills healthy cells. So your child will get a stem cell transplant, usually of his or ... Neuroblastoma is a type of cancer that forms in nerve cells called neuroblasts. ...
Cincinnati Children's Hospital Medical Center, Author Profile | Lab Manager
Scientists Tissue Engineer Human Intestines and Functioning Nerves. November 23, 2016 New technology to study human health ... Experimental Drug Targets Nucleus of Allergen-Sensitized Cells. April 20, 2017 Study suggests blocking transcription factor to ... Scientists Tissue-Engineer Part of Human Stomach in Laboratory. January 5, 2017 ... Research shows obesity causes durable and harmful changes to the hematopoietic stem cell compartment ...
Frontiers | Inflammatory stimulation preserves physiological properties of retinal ganglion cells after optic nerve injury |...
Spontaneous RGC activity decreased for the two most numerous RGC types (ON- and OFF-sustained cells) within one post-operative ... Spontaneous RGC activity decreased for the two most numerous RGC types (ON- and OFF-sustained cells) within one post-operative ... a degenerative or a regenerative state in ex vivo retinae 1 week after either optic nerve cut alone (ONC) or additional IS (ONC ... a degenerative or a regenerative state in ex vivo retinae one week after either optic nerve cut alone (ONC) or additional ...
Optic nerveConnective tissuesSciatic NerveProteinsEpithelial tissuesSpinalFunctionalNeuronalRetinal GangResearchersStem cellRegenerateProteinPhysiologyScar-TissueEmbryonicEstablish contacts with nervesBoneLungImmuneBiologyNeuralSynapsesCancersRegenerativeProliferationPeripheral nerve regenerationPhenotypeVivoCartilageGeneKinds of tissuePluripotent stemTherapiesGliaRegulationMesenchymal cellsSubstancesMiceAdiposeGlial cellsApoptosisCancerousComplex tissuesSpecific tissues
- Optic nerve sheath diameter ultrasonography is strongly correlated with invasive ICP measurements and may serve as a sensitive and noninvasive method for detecting elevated ICP in TBI patients after decompressive craniectomy 1) . (neurosurgery.directory)
- Optic nerve sheath diameter measured by transorbital ultrasound imaging is an accurate method for detecting intracranial hypertension that can be applied in a broad range of settings. (neurosurgery.directory)
- 7.5 MHz ) linear probes with improved spatial resolution have enabled excellent views of the optic nerve sheath . (neurosurgery.directory)
- The optic nerve sheath diameter (ONSD), measured at a fixed distance behind the retina has been evaluated to diagnose and measure intracranial hypertension in traumatic brain injury and intracranial hemorrhage 3) 4) . (neurosurgery.directory)
- The optic nerve sheath is fairly easy to visualize by ultrasonography by insonation across the orbit in the axial plane. (neurosurgery.directory)
- Padayachy et al present a method for assessment of optic nerve sheath ONS pulsatile dynamics using transorbital ultrasound imaging . (neurosurgery.directory)
- Of the studied ultrasound noninvasive intracranial pressure monitoring , optic nerve sheath diameter (ONSD), is the best estimator of ICP . (neurosurgery.directory)
- The novel combination of optic nerve sheath diameter ultrasonography and venous transcranial Doppler (vTCD) of the straight sinus is a promising and easily available technique for identifying critically ill patients with intracranial hypertension 10) . (neurosurgery.directory)
- Correlations between ICP and Optic nerve sheath diameter (ONSD) using CT and MRI have been observed in adult populations. (neurosurgery.directory)
- Intracranial pressure (ICP) can be noninvasively estimated from the sonographic measurement of the optic nerve sheath diameter (ONSD) and from the transcranial Doppler analysis of the pulsatility (ICPPI) and the diastolic component (ICPFVd) of the velocity waveform 14) . (neurosurgery.directory)
- This is most likely due to an impaired retraction capability of the optic nerve sheath. (neurosurgery.directory)
- Immunohistochemical analysis largely confirmed the results of the western blot analysis with often localization of Ninjurin-1 in the regions with abundant connective tissues . (bvsalud.org)
- Muscular tissues, epithelial tissues, and connective tissues. (answers.com)
- fat layer, epitheremis, dermis Tissues of the skin are epithelial tissues and connective tissues. (answers.com)
- For more results try searching for Adult Rat or Mouse Sciatic Nerve: Fresh tissue suspended in media, not frozen cells across all experimental services. (scienceexchange.com)
- Engineered neural tissue with aligned, differentiated adipose-derived stem cells promotes peripheral nerve regeneration across a critical sized defect in rat sciatic nerve. (jamesphillips.org)
- Injury to the sciatic nerve, for example, is not considered a spinal cord injury . (healthtap.com)
- In this study, we obtained a global lncRNA portrayal following sciatic nerve injury in male rats using microarray and further investigated one of these dys-regulated lncRNAs, TNXA-PS1, confirming its vital role in regulating Schwann cells. (jneurosci.org)
- Systematic lncRNA expression profiling of sciatic nerve segments following nerve injury in rats suggested lncRNA TNXA-PS1 as a key regulator of Schwann cell migration, providing a potential therapeutic target for nerve injury repair. (jneurosci.org)
- We have identified a set of dys-regulated long noncoding RNAs (lncRNAs) in rats following sciatic nerve injury and found that the expression of TNXA-PS1 was significantly downregulated. (jneurosci.org)
- An MRI was obtained to visualize the retrotrochanteric soft tissues and showed a tight scar surrounding the sciatic nerve, which was also compressed by an adjacent lipoma. (springermedizin.de)
- Therefore, she was reoperated on to remove the lipoma and the scar tissue around the sciatic nerve. (springermedizin.de)
- To decrease the risk of recurrent scarring around the sciatic nerve, an adhesion barrier was applied before closure. (springermedizin.de)
- Scar tissue around the sciatic nerve is frequently observed during revision surgery. (springermedizin.de)
- However, we feel that sciatic nerve entrapment by scar tissue should be a part of the differential diagnosis of painful THR. (springermedizin.de)
- Schuh A, Riedel F, Craiovan B, Zeiler G (2003) Delayed neuropathy of the sciatic nerve after total hip replacement with an acetabular reinforcement ring. (springermedizin.de)
- Bendszus M, Rieckmann P, Perez J, Koltzenburg M, Reiners K, Solymosi L (2003) Painful vascular compression syndrome of the sciatic nerve caused by gluteal varicosities. (springermedizin.de)
- Old human cells return to a more youthful and vigorous state after being induced to briefly express a panel of proteins involved in embryonic development, according to a new study by researchers at the Stanford University School of Medicine. (news-medical.net)
- Neuromodulator-mediated phosphorylation of specific proteins in a neurotumor hybrid cell line (NCB-20). (curehunter.com)
- This suggests that in NCB-20 cells, several unique proteins can be phosphorylated by cyclic AMP-dependent protein kinase in response to hormonal elevation of cyclic AMP levels. (curehunter.com)
- Proteins are the molecular building blocks and engines of the cell, and are involved in practically all life processes. (mpg.de)
- Composed of a limited number of proteins and often organized according to geometric principles, viral particles are effective devices in the transfer of the viral genome and proteins to host cells. (mpg.de)
- Transplantation of in vitro-expanded neural stem cells (NSCs) is a potentially powerful tool to repair functions of the injured spinal cord. (nii.ac.jp)
- We evaluated the basic characteristics of NSC-like cells from two different donor sources, the embryonic hippocampus and spinal cord, after transplantation into the neonatal spinal cord. (nii.ac.jp)
- Both NSC-like cells can survive within the environment of the intact neonatal spinal cord and showed extensive migratory behavior shortly after transplantation. (nii.ac.jp)
- In contrast, only 64% of total spinal cord cells were in the dorsal white matter. (nii.ac.jp)
- BrdU proliferation assay revealed that 10% of total hippocampal cells and 7% of total spinal cord cells were immunoreactive with BrdU. (nii.ac.jp)
- NSCs to supply the cell source for immature oligodendrocytes, which are thought to be essential for both the myelination and trophic support of regenerating axons in the dorsal white matter of the spinal cord. (nii.ac.jp)
- Within brain and spinal cord these nerves connect to other nerves via synapses on both axons and dendrites. (healthtap.com)
- While there is a lot of interest in using stem cells to regenerate injured brain, spinal cord, and eye disease, so far, these are all experimental and unproven. (healthtap.com)
- Is nerve injury the same as nerve damage or spinal cord damage? (healthtap.com)
- While spinal cord and nerves are both nervous tissue, nerves typically are structures that have branched outside the spinal cord. (healthtap.com)
- It can manifest as bumps under the skin, colored spots, bone problems, pressure on spinal nerve roots, and other neurological problems. (medicalnewstoday.com)
- There are certain "real neuroses" such as paralysis and spinal-cord disease, which involve an organic impairment of nerve-tissue. (dictionary.com)
- The formation of such extended networks and the establishment of numerous contacts suggest that dental stem cells create functional connections with nerves of the face. (innovations-report.com)
- Therefore, these cells could represent an attractive choice for the regeneration of functional, properly innervated facial tissues," adds co-author and junior group leader Pierfrancesco Pagella. (innovations-report.com)
- This information can shed light on the molecular bases for the structural and functional differences among tissues, and for important differences in tissue responsiveness to pharmacological agents and sensitivity to various pathological processes. (biomedcentral.com)
- Transcriptome profiling is widely used to infer functional states of specific cell types, as well as their responses to stimuli, to define contributions to physiology and pathophysiology. (nature.com)
- But, she said, it remains to be seen whether the germline stem cells are able to form as many kinds of functional cells as embryonic stem cells. (latimes.com)
- Axonal injuries in the optic nerve normally result in permanent functional loss due to regenerative failure of RGCs. (frontiersin.org)
- The final functional objective of regeneration is the re-establishment of tissue after injury. (frontiersin.org)
- Kinetic analyses confirmed that all cells analyzed in this study possess functional GLUTs that take up 2-deoxyglucose and DHA. (springer.com)
- Groups of different kinds of tissues are organized together to form organs, which have special functions with characteristic shapes and functional properties. (encyclopedia.com)
- Therefore, further exploration of functional molecules in the Schwann cell phenotype modulation is of great importance. (jneurosci.org)
- Tissues come together to form a functional unit called organs. (answers.com)
- Cells without functional lamellipodia are still highly motile but lose their ability to stay on track, report researchers at the Stowers Institute for Medical Research in the April 9, 2012, online issue of the Journal of Cell Biology. (redorbit.com)
- Unlike previous studies, which had mostly relied on RNA interference to reduce the concentration of functional Arp2/3 complex and had reached conflicting conclusions, Li and her team opted for the genetic disruption of the ARP2/3 complex to determine its function in fibroblast cell motility. (redorbit.com)
- Mouse neuroblastoma X embryonic Chinese hamster brain explant hybrid cell line (NCB-20) forms functional synapses when intracellular cyclic AMP levels are elevated for a prolonged period of time. (curehunter.com)
- A team of researchers led by Thimios Mitsiadis, professor at the Institute of Oral Biology of the University of Zurich, has now published two studies that elucidate how stem cells promote neuronal growth in tissue regeneration and in cancer progression. (innovations-report.com)
- Using the "organ-on-a-chip" technology, which relies on small three-dimensional devices mimicking the basic functions of human organs and tissues, the researchers demonstrated that both types of stem cells promoted neuronal growth. (innovations-report.com)
- Neuronal growth is a fundamental event during ontogenetic development and nerve regeneration. (pnas.org)
- This study analyzed the effects of oxidative stress and DHA uptake on neuronal cell death in vitro. (springer.com)
- Thus, DHA promotes the death of stressed neuronal cells, which is reversed by incubating the cells with cytochalasin B, an inhibitor of DHA uptake by GLUT1 and GLUT3. (springer.com)
- Li X, Huang J, May JM (2003) Ascorbic acid spares alpha-tocopherol and decreases lipid peroxidation in neuronal cells. (springer.com)
- On the neuronal side, ion channels, nerve cells and brain tissue are employed. (mpg.de)
- Hence, the incorporation of neuroactive molecules into electroconductive polymers via a specific and stable method is essential for neuronal tissue engineering applications. (royalsocietypublishing.org)
- Researchers at the University of Zurich show that different stem cell populations are innervated in distinct ways. (innovations-report.com)
- In the second study, the researchers examined the interaction between nerves and cancer stem cells found in ameloblastoma, an aggressive tumour of the mouth. (innovations-report.com)
- In 2011 researchers at the same center announced that they had grown intestinal tissue-but it was missing nerve cells and so was unable to contract in the undulating motion that pushes food along a colon. (georgetown.edu)
- Eventually, the researchers hope to treat people with gastrointestinal problems by making copies of a patient's gut to observe how a disease manifests-or even to transplant the tissue. (georgetown.edu)
- First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. (biologists.org)
- The current challenge for researchers is to develop a biomimetic scaffold that is capable of stimulating the re-growth of the native tissue, thus structurally mimicking the extracellular matrix (ECM), providing chemical guidance cues and mechanical support for re-enervation of the damaged region. (nus.edu.sg)
- A team of researchers at Tufts University School of Medicine developed a method to grow and maintain olfactory stem cells in culture, which can then be used to restore tissue in the nose. (scienceandtechnologyresearchnews.com)
- In this study, the researchers determined the optimal conditions for expanding and maintaining healthy HBC stem cells in culture, borrowing methods and factors used to maintain respiratory stem cells. (scienceandtechnologyresearchnews.com)
- The stem cells offer another potential alternative to embryonic stem cells for researchers who aim to treat diseases such as diabetes and Parkinson's by replacing damaged or malfunctioning cells with custom-grown replacements. (latimes.com)
- Researchers from Chalmers University of Technology, Sweden, have created a new, rubber-like material with a unique set of properties, which could act as a replacement for human tissue in medical procedures. (news-medical.net)
- Researchers are using the tissue, synthesized with human pluripotent stem cells and implanted into mice, to study a rare form of Hirschprung's disease. (the-scientist.com)
- Using genes inserted into two types of human cells, fibroblasts and glia cells, researchers showed that it is possible to reprogram other cells to become nerve cells directly in the brain. (scitechdaily.com)
- A new report from researchers at Lund University in Sweden shows that it is possible to reprogram other cells to become nerve cells, directly in the brain. (scitechdaily.com)
- Two years ago, researchers in Lund were the first in the world to reprogram human skin cells, known as fibroblasts, to dopamine-producing nerve cells - without taking a detour via the stem cell stage. (scitechdaily.com)
- Once the researchers had transplanted the cells into the brains of rats, the genes were activated using a drug in the animals' drinking water. (scitechdaily.com)
- The Stowers researchers derived mouse embryonic stem (ES) cells from animals that lacked the gene encoding the ARPC3 subunit of the Arp2/3 complex and normal control mice and differentiated them into fibroblasts. (redorbit.com)
- To find out whether the inability to form lamellipodia impacted cells' ability to move, the researchers used a wound healing-assay to test cell motility. (redorbit.com)
- The researchers also want to find out what the actual protein composition of the cell looks like and how complete biological systems function. (mpg.de)
- Researchers of the MPI for Molecular Biomedicine in Münster have made an important advancement towards obtaining patient-specific stem cells. (mpg.de)
- A team of researchers spoke to News-Medical about their latest research investigating whether micro and nanoplastics are accumulating in human tissues. (news-medical.net)
- Now, however, a team of researchers from a range of disciplines in the University - from engineering to biology - have discovered a novel, electronically-controlled method of generating dynamic cell patterns using a portable device based on acoustic force for spatial manipulation of cells and particles. (phys.org)
- Dr Mathis Riehle, a reader in the Institute of Molecular Cell and Systems Biology, said the researchers' ambition was to turn what is currently a two-dimensional application into one that is three-dimensional. (phys.org)
- In this review, we discuss the different stem cell types that are showing promise for nervous system tissue engineering in the context of peripheral nerve injury. (hindawi.com)
- When ameloblastoma cells were isolated and placed in the "organ-on-a-chip" devices, they retained not only their stem cell properties but also attracted nerves and established contact with them. (innovations-report.com)
- Published today in the journal Stem Cell Reports , the development paves the way for further research into stem cell transplantation therapies, or pharmacological approaches that stimulate stem cells within the nose to regenerate tissue. (scienceandtechnologyresearchnews.com)
- The trigger used was retinoic acid, which has the effect of lowering levels of the protein P63 in the cells, leading to stem cell activation. (scienceandtechnologyresearchnews.com)
- Experiments in mice suggested that reproductive cells -- also known as germ cells -- were good candidates for making stem cells because they naturally express low levels of the "pluripotency" genes that make embryonic stem cells so versatile, said Renee A. Reijo Pera, director of the Center for Human Embryonic Stem Cell Research and Education at Stanford University, who was not involved in the study. (latimes.com)
- This would be a great way to produce pluripotent stem cells," said Kathrin Plath, a researcher at the Broad Center of Regenerative Medicine and Stem Cell Research at UCLA, who was not involved in the study. (latimes.com)
- The purpose of this study is to evaluate the feasibility and efficacy of reduced-intensity allogeneic stem cell transplantation (RIST) with RIC regimen in children with neuroblastoma who have failed a prior autologous stem cell transplantation. (clinicaltrials.gov)
- Therefore, a strategy using high-dose chemotherapy and autologous stem cell transplantation (HDCT/auto-SCT) has been explored to improve the prognosis of patients with high-risk NB. (clinicaltrials.gov)
- In this context, allogeneic stem cell transplantation (allo-SCT) has been tried as salvage treatment in patients with NB who have failed a prior auto-SCT. (clinicaltrials.gov)
- High-dose chemotherapy and radiation therapy with stem cell rescue. (medlineplus.gov)
- So your child will get a stem cell transplant , usually of his or her own cells collected earlier. (medlineplus.gov)
- The ability to regenerate whole-body structures has been studied for many decades and is of particular interest for stem cell research due to its therapeutic potential. (frontiersin.org)
- A stem-cell matrix can repair brain damage in rodents. (technologyreview.com)
- Correlation of HIWI and HILI Expression with Cancer Stem Cell Markers in Colorectal Cancer. (cancerindex.org)
- Side effects can happen any time during, immediately after or days to months after stem cell transplant. (cancer.ca)
- Short-term, or acute, side effects generally develop during the first 100 days after a stem cell transplant. (cancer.ca)
- A stem cell transplant is a very complex procedure. (cancer.ca)
- Side effects of stem cell transplant can be very serious or even life-threatening. (cancer.ca)
- The healthcare team watches people receiving a stem cell transplant very closely. (cancer.ca)
- All types of stem cell transplants share some of the same side effects. (cancer.ca)
- Other side effects are unique to high-dose therapy and stem cell transplant. (cancer.ca)
- The following are the most common side effects that people tend to experience with stem cell transplant. (cancer.ca)
- Tell your healthcare team if you have these side effects or others you think might be from stem cell transplant. (cancer.ca)
- Infection is one of the most common early side effects of a stem cell transplant. (cancer.ca)
- Infection occurs after stem cell transplant because the white blood cell count is very low and the immune system is very weak. (cancer.ca)
- People who have a stem cell transplant need to take special precautions until their white blood cell counts are back to normal and their bodies can fight infections. (cancer.ca)
- Many people who receive a stem cell transplant have to follow dietary restrictions and food safety guidelines. (cancer.ca)
- Doctors may also prescribe colony-stimulating factors (CSFs), such as filgrastim (Neupogen) or pegfilgrastim (Neulasta), following a stem cell transplant to help lower the risk of infection and speed up engraftment. (cancer.ca)
- Infection can also occur long after a stem cell transplant. (cancer.ca)
- This could make future stem cell therapies simpler and safer. (mpg.de)
- A PML-PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance. (yu.edu)
- To kick off the 2018 Till & McCulloch Meetings in style, the Stem Cell Network and CCRM will be hosting a welcome reception on the evening of Sunday November 11. (cvent.com)
- Once we determined that we could grow HBCs in the lab, and that they expressed the same identifying molecular markers found in vivo, we sought to confirm whether they would work as well as the in vivo HBCs - can they regenerate tissue that has been injured - and they did! (scienceandtechnologyresearchnews.com)
- The aim of this area is to prepare a lung-on-a-chip for the development of novel strategies to regenerate damaged lung tissue. (utwente.nl)
- Marian Blanca Ramírez from the CSIC in Spain has been studying the effects of LRRK2, a protein associated with Parkinson's disease, on cell motility. (biologists.org)
- Immunofluorescence revealed that this protein is a useful oligodendrocyte cell-type marker in rodent and primate ONs. (biomedcentral.com)
- The so-called germline stem cells grew nearly as fast as embryonic stem cells and produced many of the specialized protein markers associated with embryonic stem cells. (latimes.com)
- Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. (cancerindex.org)
- The encoded protein contains a high mobility group-box DNA binding domain and participates in the regulation of cell cycle genes and cellular senescence. (cancerindex.org)
- Dead and dying nerve cells contain tangles, which are made up of twisted strands of another protein. (alz.org)
- In this study, we analyzed the prognostic value of epithelial membrane protein 3 (EMP3) in terms of overall survival (OS) in glioblastoma multiforme (GBM) and the association between its expression and DNA methylation.Bioinformatic analysis was performed by using data from the Cancer Genome Atlas (TCGA) database.EMP3 expression was markedly higher in GBM tissues than in normal brain tissues. (bireme.br)
- The Interleukin (IL) -1 (IL-1), IL-6, IL-10, tumor necrosis factor alpha (TNF-a), protein C-reactive (CRP) and white blood cells count were measured at rest, immediately post-exercise, and at 24, 48, 72, 96 h in post-exercise recovery. (slideshare.net)
- D-Ala2,D-Leu enkephalin , which decreased cyclic AMP levels and reversed the 2-chloroadenosine-stimulated phosphorylation of tyrosine hydroxylase in differentiated PC12 cells, also reversed the stimulation of phosphorylation of the 90-kDa protein in NCB-20 cells. (curehunter.com)
- These products of cell metabolism are primarily nitrogenous substances derived from protein, especially ammonia, or possibly certain short-chain fatty acids. (britannica.com)
- Our findings open up the possibility of anti-inflammatory drugs that are more tissue-specific and don't have NSAIDs' side effects," said the study's senior author Benjamin F. Cravatt, chair of the Department of Chemical Physiology and member of the Skaggs Institute for Chemical Biology and the Dorris Neuroscience Center at Scripps Research. (healthcanal.com)
- Anatomy and Physiology Microscope Slide Set for biology and life science illustrates the fascinating diversity and specialization of tissues which comprise the various organ systems of the mammalian body. (flinnsci.com)
- They are theoretically superior to traditional embryonic stem cells because they can be obtained directly from male patients and used to grow replacement tissue that their bodies won't reject, Sabine Conrad of the University of Tuebingen in Germany and her colleagues wrote. (latimes.com)
- After about three weeks, some of the cells formed colonies resembling embryonic stem cells, the team reported. (latimes.com)
- Reijo Pera said germline stem cells do not have a completely blank slate like embryonic stem cells or the reprogrammed skin cells known as induced pluripotent stem cells. (latimes.com)
- Therapy based on embryonic stem cells improved patients. (latimes.com)
- Our study is the first one to use knock-out mice and differentiated mouse embryonic stem cells to dissect the function of Arp2/3 in fibroblast cell motility," says postdoctoral researcher and lead author Praveen Suraneni, Ph.D. Fibroblasts are very mobile and have become the standard model to study cell motility. (redorbit.com)
- Li and her team are now planning to look at different cell types derived from ARPC+/+ and ARPC-/- mouse embryonic stem cells. (redorbit.com)
- They have succeeded in resetting adult somatic cells to an embryonic original state with less intrusions than previously necessary: instead of a „cocktail" of four genes, the scientists needed merely two. (mpg.de)
Establish contacts with nerves1
- Stem cells can generate a variety of specific tissues and are increasingly used for clinical applications such as the replacement of bone or cartilage. (innovations-report.com)
- Both can differentiate into various cell types such as bone, cartilage and fat cells. (innovations-report.com)
- Human bone marrow stem cells are isolated from skeletal bones and are the gold standard for bone regenerative approaches. (innovations-report.com)
- Human dental pulp stem cells exhibit enhanced properties in comparison to human bone marrow stem cells on neurites outgrowth. (innovations-report.com)
- A sarcoma is a cancerous tumor of the bone or soft tissue. (bidmc.org)
- Sarcomas are divided into two main groups - bone sarcomas and soft tissue sarcomas. (bidmc.org)
- To confirm the diagnosis, the physician will surgically remove some of the tissue from the tumor or bone marrow ( biopsy ), and examine the cells under the microscope. (encyclopedia.com)
- The risk of infection for all types of transplant is high until the bone marrow starts to make white blood cells, which is called engraftment. (cancer.ca)
- The alveolar bone (C) is surrounded for the most part by the subepithelial connective tissue of the gingiva, which in turn is covered by the various characteristic gingival epithelia. (wikipedia.org)
- skin tissues, mussle tissues, organ tissues and bone tissues. (answers.com)
- Nerve growth factor (NGF) is over-expressed in patients with lung inflammatory diseases including airway virus infections. (cdc.gov)
- Optimum airway surface liquid (ASL), controlled by epithelial cells, is essential for normal lung function. (cdc.gov)
- In this project, lung alveolar epithelial cells and microvascular endothelial cells will be cultured on curved, flexible and elastic PTMC membranes in a chip. (utwente.nl)
- This lung-on-a-chip will subsequently be used to develop novel strategies for lung regeneration as well as the engineering of bioartificial lung tissue. (utwente.nl)
- These amino acids are required for tissue building and repair, playing an important role in immune function, taking part in various biochemical reactions and are vital for metabolism. (hindustantimes.com)
- Their study provides new insight into cell motility, a complex and integrated process, which, when gone awry, can lead to various disease conditions such as cancer metastasis, birth defects, cardiovascular disease and compromised immune function. (redorbit.com)
- B cells are important in helping the immune system fight pathogens. (news-medical.net)
- The fight against illnesses and pathogens requires activation or deactivation of a large number of different cell types in our immune system at the right place and the right time. (news-medical.net)
- In recent years certain immune cells, the myeloid-derived suppressor cells (MDSCs), have been receiving increasing attention in this context. (news-medical.net)
- B cells can develop into cells which produce antibodies, but they can also activate other immune cells by secreting immune messengers. (news-medical.net)
- or, B cells activate immune cells in the blood and lymph systems which then move to the meninges, where they cause damage. (news-medical.net)
- Nerves are fundamental for regulating the physiological and regenerative processes involving stem cells. (innovations-report.com)
- The nerves that confer the sense of smell are unique when compared to the rest of the nervous system, in that they can trigger a robust and nearly complete regenerative response after injury. (scienceandtechnologyresearchnews.com)
- In the current study, we investigated the signal propagation in single intraretinal axons as well as characteristic activity features of RGCs in a naive, a degenerative or a regenerative state in ex vivo retinae 1 week after either optic nerve cut alone (ONC) or additional IS (ONC + IS). (frontiersin.org)
- It remains unclear whether the reported changes are a consequence of decreased cell density or arise at single-cell level which would be necessary to investigate the health status of surviving RGCs or susceptibility to regenerative treatments after optic nerve cut. (frontiersin.org)
- Trainees and HQP interested in connecting with experts and leaders the field of stem cells and regenerative medicine should gather in the Governor General III Room for this valuable networking and career building event. (cvent.com)
- A majority of progenitor cells migrated through dorsal white matter without proliferation during the period of one week after transplantation. (nii.ac.jp)
- In this study, we examined apoptosis, proliferation, migration, and survival of newborn cells in the young (2 weeks), young-adult (6 weeks), middle-aged (12 months), and old (24 months) rat DG. (nih.gov)
- We show that new cell proliferation and apoptosis slow down profoundly over this time period. (nih.gov)
- The main focus of this area is to understand and improve the adhesion and proliferation of endothelial cells on natural and artificial surfaces. (utwente.nl)
Peripheral nerve regeneration1
- Both NSC-like cells showed restricted phenotype toward the oligodendroglial lineage after transplantation. (nii.ac.jp)
- V. Correlate NK cell persistence, phenotype, and function with overall response. (clinicaltrials.gov)
- BACKGROUND: Rh phenotype is an extremely rare condition characterized by no expression of Rh antigens at the surface of red blood cells. (bireme.br)
- We conclude that the new cDNA library is a faithful representation of human ON and EST data provide an initial overview of gene expression patterns in this tissue. (biomedcentral.com)
- While many cDNA libraries are normalized (a subtraction hybridization approach to reduce the representation of abundant clones) or amplified (an expansion in which different clones proliferate at different rates), most NEIBank libraries are unnormalized and unamplified so that random sequencing for EST analysis reflects more closely the natural abundance of common gene transcripts in each tissue. (biomedcentral.com)
- Single-cell sequencing reveals dissociation-induced gene expression in tissue subpopulations. (nature.com)
- Moreover, the description of the stomach as the major source of the novel anorexigenic hormone nesfatin-1 derived from the NUCB2 gene further corroborated the assumption that the gastric X/A-like cell products are not only stimulant but also inhibitors of feeding, thereby acting as so far unique dual regulator of food intake located in a logistically important place where the gastrointestinal tract has initial contact with food. (biomedsearch.com)
- The mutation in the gene means that the nerve tissue is not properly controlled. (medicalnewstoday.com)
- This gene encodes a member of the T cell factor/lymphoid enhancer factor family of transcription factors. (cancerindex.org)
- In primary nasal epithelial cells transfected with the human telomerase reverse transcriptase gene, knockdown of p63 by siRNAs induced claudin-4 expression. (bireme.br)
- Claudin-4 knockout by TALEN-mediated gene targeting in MDCK cells: Claudin-4 is dispensable for the permeability properties of tight junctions in wild-type MDCK cells. (bireme.br)
Kinds of tissue3
- The ON consists of the myelinated axons of retinal ganglion cells (RGC), their supporting glia, oligodendrocytes and vascular elements, all enclosed by a fibrous sheath. (biomedcentral.com)
- The genes were inserted into two types of human cells: fibroblasts and glia cells - support cells that are naturally present in the brain. (scitechdaily.com)
- In a separate experiment on mice, where similar genes were injected into the mice's brains, the research group also succeeded in reprogramming the mice's own glia cells to become nerve cells. (scitechdaily.com)
- Your nerves need these substances to send signals. (medlineplus.gov)
- The alkaloid kills insects by disrupting their neurotransmitters, substances released by the bug's activated nerve cells. (nytimes.com)
- If liver cells are damaged, certain substances that are normally cleansed from the blood by the healthy liver are not removed. (britannica.com)
- However, stem cells are also present in cancerous tissues and are involved in cancer progression and metastasis. (innovations-report.com)
- The expression level of HIWI and HILI and cancer stem cells markers in paired cancerous and non-cancerous tissues was measured by real-time reverse transcription-polymerase chain reaction (RT-PCR) assay. (cancerindex.org)
- A non-cancerous (benign) soft tissue tumour is a growth that does not spread (metastasize) to other parts of the body. (cancer.ca)
- There are many types of non-cancerous soft tissue tumours. (cancer.ca)
- Many non-cancerous soft tissue tumours start in the fat tissue of the body including the following. (cancer.ca)
- Lipoma is the most common type of non-cancerous soft tissue tumour. (cancer.ca)
- Different non-cancerous tumours can develop in fibrous tissues. (cancer.ca)
- Superficial fibromatosis is when small non-cancerous tumours develop in the tissues of the hands, feet or penis. (cancer.ca)
- Desmoid-type fibromatosis is a soft tissue tumour that is usually non-cancerous. (cancer.ca)
- A benign (non-cancerous) brain tumour is a mass of cells that grows relatively slowly in the brain. (www.nhs.uk)
- There are many different types of non-cancerous brain tumours, which are related to the type of brain cells affected. (www.nhs.uk)
- Cell-type-specific isolation of ribosome-associated mRNA from complex tissues. (nature.com)
- Simple and complex tissues are conducting tissues. (answers.com)
- Cells of different types of permanent tissues are called as complex tissues. (answers.com)
- Conducting tissues referred to as complex tissues because complex tissues are made up of more than one type of cells. (answers.com)