Cells cell division. Medical search

Although a number of molecules have been implicated in regulation of asymmetric stem cell division, here, we highlight known tumor suppressors with established roles in this process. (elsevier.com)
Mutations in tumor suppressors involved in asymmetric stem cell division provide mechanisms by which cancer stem cells can hyperproliferate and offer an intriguing new focus for understanding cancer biology. (elsevier.com)

Asymmetric stem cell division has emerged as a major regulatory mechanism for physiologic control of stem cell numbers. (elsevier.com)

Reinvigoration of the cancer stem cell theory suggests that tumorigenesis may be regulated by maintaining the balance between asymmetric and symmetric cell division. (elsevier.com)

The cell is actually split in two in a process called cytokinesis, in which the cellular membrane is pinched in the middle like a balloon squeezed in the center. (encyclopedia.com)
Cytokinesis then divides the rest of the cell, and two identical cells result. (encyclopedia.com)
And this is what the cell does using Topo 2", explains Manuel Mendoza, head of the Coordination of Cytokinesis with Chromosome Segregation group at the CRG. (eurekalert.org)
Since other cells, including human cells, depend on similar proteins for cytokinesis [cell division], it is entirely possible that they use the same strategy. (eurekalert.org)
Bacterial cell division is essential and requires the recruitment and regulation of a complex network of proteins needed to initiate and guide constriction and cytokinesis. (asm.org)
Interphase is the process a cell must go through before mitosis, meiosis, and cytokinesis . (wikipedia.org)
After the cell proceeds successfully through the M phase, it may then undergo cell division through cytokinesis. (wikipedia.org)
At the peak of the cyclin attached to the cyclin dependent kinases this system pushes the cell out of interphase and into the M phase, where mitosis, meiosis, and cytokinesis occur. (wikipedia.org)
Mitosis is specifically the division happening of the nucleus whereas cytokinesis follows to do the actual splitting of the cell (mentioned at 7:30 ). (youtube.com)
Both the cell-free egg extract system and embryos recruit critical signaling molecules necessary for cytokinesis signaling. (phys.org)
The name given to this process by those early biologists, cytokinesis, translates as "cell movement" and captures the sense of a highly active and organized series of events. (phys.org)
Now Harvard Medical School systems biologists report in Science that they have reconstituted cytokinesis-complete with signals that direct molecular traffic-without the cell. (phys.org)
Quickly removing and returning proteins to see how changes in the molecular players affect cytokinesis is impossible when the cell is whole, but easy when the cellular innards are spread out on a microscope slide. (phys.org)
The key challenge, though, was that the behavior of cytokinesis is entirely dependent on having a membrane to furrow-and membranes are exactly what have to be removed to make the system cell-free. (phys.org)
To really prove that we reconstituted the cytokinesis signal, we needed to add the bilayer membrane and then see if it could recruit the proteins that would be on the cortex of the cell," Field said about the specialized layer beneath the cell membrane. (phys.org)
Mitosis and cytokinesis, the period of active cell division, is followed by a period of non-division known as interphase. (abpischools.org.uk)
Along with cytokinesis (the division of the rest of a cell), mitosis results in a parent cell dividing into two daughter cells. (pbs.org)
Nuclear division divides the genetic material in the nucleus, while cytokinesis divides the cytoplasm. (cliffsnotes.com)
Simultaneously, cytokinesis occurs, dividing the cytoplasm into two cells. (cliffsnotes.com)
This led Flemming to discover the cell process that we call mitosis: division of the eukaryotic cell nucleus that occurs just prior to cytokinesis , which is the division of the cell itself. (visionlearning.com)
This occurs at a precise stage cytokinesis when the cell splits into two new daughter cells. (nanowerk.com)
Division is a complex and robust process that is generally performed flawlessly, but when an error occurs in DNA separation or during cytokinesis, it can be a source for triggering cancer, for example, said Hickson. (nanowerk.com)

When DNA is replicated before the cell divides, each chromosome has two identical copies of DNA called sister chromatids. (encyclopedia.com)
It is a two-step process that reduces the chromosome number by half-from 46 to 23-to form sperm and egg cells. (medlineplus.gov)
Errors in cell division can cause mutations that lead to cancer, and this study could shed light on the role of chromosome abnormalities in uncontrolled cell replication. (redorbit.com)
Once the whole chromosome has been replicated, these three proteins form a band-like structure over the cell equator. (innovations-report.com)
2) Our video is intended to focus on animal cells (as drawn) - specifically human cells - as we use human chromosome numbers. (youtube.com)
During meiosis, the genetic material replicates and is divided between daughter cells so that each gamete contains a single copy of each chromosome instead of two copies. (reference.com)
Most eukaryotic cells have 2 copies of every chromosome. (prezi.com)
Early during cell division, each chromosome is duplicated and split into two identical copies known as chromatids, which must be sorted and organized to ensure that new cells receive a single copy of each chromosome. (news-medical.net)
by the end of this phase each chromosome in the cell consists of two chromatids attached at the centromere. (flashcardmachine.com)
In order to replicate its entire DNA, that is to say nearly 6.4 billion pairs of nucleotides in just a few hours, the cell organizes the preparation of this process at thousands of sites on each chromosome simultaneously. (eurasiareview.com)
A complete chromosome set must be apportioned to each daughter cell during cell division. (sciencemag.org)
Phosphorylation of the chromatin protein histone H2A plays a critical role in chromosome segregation during cell division. (sciencemag.org)
It appears that cells lacking pericentrin have abnormal chromosome segregation, which leads, in some fraction of cells, to arrest of the cell cycle and possibly cell death. (gnxp.com)
Now researchers from the European Molecular Biology Laboratory for the first time tracked chromosome condensation in mammalian cells over the entire course of cell division. (brightsurf.com)
In this week's advanced online publication of Nature Cell Biology they report crucial new insights into timing, function and molecular basis of chromosome condensation. (brightsurf.com)
In Drosophila and also in humans impairment of chromosome segregation during cell division may contribute to disease and birth defects. (healthcanal.com)
Thus, errors in centromere function can lead to chromosome instability and aberrant cell division, both of which are often observed in cancer cells. (healthcanal.com)
Several other proteins are involved in different steps of the cell division process such as site selection (Min proteins, Noc, SlmA) and chromosome segregation (Smc proteins) (for review see Goehring and Beckwith, 2005). (scielo.br)
Somatic cells (all body cells except eggs and sperm) are diploid cells because each cell contains two copies of every chromosome. (cliffsnotes.com)
It is a huge challenge to divide these long tangled chromosome strands correctly. (ed.ac.uk)
In biochemical experiments where you look at an average of what is going on in all cells of a population, that synchrony meant we could see every step along the pathway of chromosome formation. (ed.ac.uk)

may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. (wikimedia.org)
It constricts the cell membrane into a cleavage furrow that eventually pinches the cell in two. (eurekalert.org)
Time-lapse imaging and computer modeling demonstrated that cells undergoing mitosis set up small clusters of proteins, or nodes, on the inside of the cell membrane around the equator of the cell. (eurekalert.org)
What kind of molecules pass through a cell membrane most easily? (reference.com)
The type of molecules that pass most readily through a cell membrane are nonpolar molecules, such as water, oxygen, carbon dioxide and fatty substrates. (reference.com)
Combining frog-egg extracts with lipid membranes that mimic the membrane of the cell, they built a cell-free system that recapitulates how the cleavage furrow is assembled. (phys.org)
What made this work possible was the realization that a controlled, flat membrane-made from two layers of artificial lipid supported on glass-could substitute for the curved, constantly moving and complex membrane of the cell. (phys.org)
The final component was the model of the cell membrane. (phys.org)
The outer membrane furrows and seems to pinch in, but ultimately does not close itself off to form two complete cells. (wisconline.com)
The red outer membrane is complete around each new cell, while the green midbody still remains between them. (wisconline.com)
published recently in the electronic journal eLife, has revealed that in the sea squirt embryo, the orientation of the cell division machinery in epithelial cells is controlled by a unique cell membrane structure, which we call an 'invagination. (brightsurf.com)
This protein polymerizes to form the Z-ring, a structure associated to the cytosolic face of the inner membrane at midcell and essential for recruitment of other proteins to the division site. (scielo.br)
As the microfilaments shorten, they act like purse strings to pull the plasma membrane into the center, dividing the cell into two daughter cells. (cliffsnotes.com)
During such a division process, the outer cell membrane has to undergo a series of morphological transformations that ultimately lead to membrane fission. (mpg.de)
Division process of an artificial cell (red), which is controlled by the protein concentration (green) in the outer aqueous solution: (I) Low protein concentrations induce a prolate or dumbbell shape of the cell with a wide membrane neck. (mpg.de)
A further increase in the protein concentration leads to a closed membrane neck in (II) and to a curvature-induced constriction force that cleaves this neck in (III), thereby creating two separate daughter cells. (mpg.de)
These cells are provided by giant lipid vesicles, which have the size of a typical animal cell and are bounded by a single lipid membrane, which provides a robust and stable barrier between the interior and exterior aqueous solution. (mpg.de)
On the one hand, artificial cells with a wide membrane neck remain stable for days and weeks. (mpg.de)
On the other hand, as soon as the neck has closed down the membrane generates a constriction force onto this neck that cleaves the neck and divides the artificial cell into two daughter cells. (mpg.de)
Furthermore, once a closed membrane neck has been formed, the spontaneous curvature generates a local constriction force that leads to the division of these cells. (mpg.de)
Thus, quite surprisingly, the complete division of the artificial cells is driven by the mechanical properties of the membranes: the force that divides the membrane neck arises directly from the asymmetry of the bilayer membranes. (mpg.de)
Furthermore, the used density of the membrane-bound proteins was rather low which leaves ample space for other proteins to be accommodated on the artificial cell membranes. (mpg.de)
DHODH also binds a lipid in the cell's mitochondrial respiratory chain complex, suggesting the enzyme might use special lipids to locate the correct binding site on the cell membrane, Landreh said. (fiercebiotech.com)

In Drosophila, this process has been analyzed in great detail and several of the key players that control asymmetric cell division in the developing nervous system have been identified over the past years. (nih.gov)
Asymmetric cell division in vertebrate neurogenesis has been studied mostly at a descriptive level and so far little is known about the molecular mechanisms that control this process. (nih.gov)
In this review we will focus on recent findings dealing with asymmetric cell division during neurogenesis in Drosophila and vertebrates and will discuss common principles and apparent differences between both systems. (nih.gov)
Hawkins ED, Russell SM (2008) Upsides and downsides to polarity and asymmetric cell division in leukemia. (springer.com)
Pham K, Sacirbegovic F, Russell SM (2014) Polarized cells, polarized views: asymmetric cell division in hematopoietic cells. (springer.com)

All organisms regulate cell cycle progression by coordinating cell division with DNA replication status. (asm.org)
In eukaryotes, DNA damage or problems with replication fork progression induce the DNA damage response (DDR), causing cyclin-dependent kinases to remain active, preventing further cell cycle progression until replication and repair are complete. (asm.org)
Meiosis results in four haploid daughter cells by undergoing one round of DNA replication followed by two divisions. (wikipedia.org)
All cell divisions, regardless of organism, are preceded by a single round of DNA replication . (wikipedia.org)
G 1 is a time of growth for the cell where specialized cellular functions occur in order to prepare the cell for DNA Replication. (wikipedia.org)
In humans, telomeres limit cells to ~50 divisions, which is probably related to how DNA replication is only 99.9998% accurate. (slashdot.org)
Human DNA replication (in normal cells with no damage) is 99.99999999% accurate (i.e. about 1 mutation per 10^-10 base pairs). (slashdot.org)
This consists of isolating and sequencing the newly synthesized DNA from cells that have just entered the replication phase, in order to map on the genome the sites where replication has begun. (eurasiareview.com)
Initially, the cell identifies all potential replication origins with a molecular marker. (eurasiareview.com)
We have discovered that in normal cells, the aberrant replication origins are subsequently eliminated. (eurasiareview.com)
The activation of the oncogenes Cyclin E or Myc, on the other hand, induces the cells to begin replication of their DNA prematurely, without having had time to eliminate all the replication origins present in the genes. (eurasiareview.com)
Our earlier data showed that cancer cells utilize this unusual form of DNA replication far more often than normal cells, because cancer cells have a lot of 'replication stress' in S-phase due to the cell division cycle being perturbed by the over-activity of cancer-causing genes called oncogenes,' says Ian Hickson. (news-medical.net)
MiDAS helps cells to finish DNA replication that is not completed in S-phase. (news-medical.net)
Cell division and replication are fundamental biological processes that occur in all organisms. (alison.com)
And without DNA replication, cell division would not occur. (icr.org)

Meiosis is the process of cellular division that produces the gametes which take part in sexual reproduction. (encyclopedia.com)
Where mitosis produces two daughter cells from one mother cell, meiosis produces four daughter cells from one mother cell. (encyclopedia.com)
Meiosis II is similar to mitosis - sister chromatids split apart into new cells - and the same steps occur in the same order. (encyclopedia.com)
There are two types of cell division: mitosis and meiosis. (medlineplus.gov)
Meiosis is the type of cell division that creates egg and sperm cells. (medlineplus.gov)
Meiosis also allows genetic variation through a process of DNA shuffling while the cells are dividing. (medlineplus.gov)
Mitosis and meiosis, the two types of cell division. (medlineplus.gov)
North Dakota State University's Virtual Cell Animation Collection offers videos that illustrate the processes of mitosis and meiosis . (medlineplus.gov)
The other type of cell division is called meiosis, and it is how the body produces eggs or sperm. (reference.com)
Meiosis features color photomicrographs (2,400x) of lily pollen and color diagrams of centrioles and asters found only in animal cells. (carolina.com)
The M phase, can be either mitosis or meiosis depending on the type of cell. (wikipedia.org)
Germ cells , or gametes, undergo meiosis, while somatic cells will undergo mitosis. (wikipedia.org)
10) is parent cell pat of meiosis? (smore.com)
Meiosis is the type of cell division that produces gametes, the reproductive cells of a sexually reproducing organism. (reference.com)
Meiosis only occurs in primordial germ cells in the reproductive organs and not in somatic cells, which make up the majority of the cells in the body. (reference.com)
In males, meiosis is called spermatogenesis because it produces sperm cells. (reference.com)
Maternal age and environmental factors may contribute to meiosis errors, although in some cases errors occur simply as a result of natural inefficiencies in the process of cell division. (reference.com)
Meiosis produces four gamete cells. (reference.com)
In contrast, meiosis is a reduction division, producing daughter cells that contain half the genetic information of the parent cell. (cliffsnotes.com)

Each new cell has exactly the same genetic material (DNA) as the cell that produced it. (encyclopedia.com)
Because each gamete has half the genetic material of the mother cell, this fusion results in a zygote with the correct amount of genetic material. (encyclopedia.com)
It involves a fairly complex process known as "mitosis", during which the cell duplicates its genetic material and separates it into two identical halves, which are then split apart. (eurekalert.org)
Prokaryotes ( bacteria ) undergo a vegetative cell division known as binary fission , where their genetic material is segregated equally into two daughter cells. (wikipedia.org)
A change in the arrangement or amount of genetic material in a cell. (abpischools.org.uk)
Recent genetic studies have shown that the function of Cdc42 in regulating cell polarity appears highly conserved from budding yeast to humans. (springer.com)
The genetic information within each of these daughter cells is identical. (pbs.org)
Two is important," Megraw said, "because you divide your genetic material into two equal sets. (scienceblog.com)
Human cells use a timer to divide: each cell gets at least 30 minutes to divide its genetic material between the nuclei of two daughter cells. (brightsurf.com)
In doing so, cells have to produce a copy of their genetic material (DNA) and separate it into two identical sets, one for each daughter cell. (healthcanal.com)
Given the essential roles of the centromeric CenH3 during cell division and the similarities in centromeric structure and function observed among all eukaryotes, the insights into Drosophila centromere stability provided by Azorín's group may contribute to our understanding of the genetic basis of cancer. (healthcanal.com)
When trying to divide and produce two daughters, one problem the cell has is there is such a huge length of DNA encoding our genetic blueprint. (ed.ac.uk)
These must be duplicated prior to division so that each of the daughter cells can receive a full complement of identical genetic material. (ed.ac.uk)

Cellular division has three main functions: (1) the reproduction of an entire unicellular organism, (2) the growth and repair of tissues in multicellular animals, and (3) the formation of gametes (eggs and sperm) for sexual reproduction in multicellular animals. (encyclopedia.com)
The growth of a fertilized embryo is accomplished through the division and differentiation of cells, a. (bookrags.com)
These fundamental discoveries have a great impact on all aspects of cell growth" and "may in the long term open new possibilities for cancer treatment," said the prize citation. (newscientist.com)
Focusing on Escherichia coli in steady growth, we quantify cell division control using a stochastic model, by inferring the division rate as a function of the observable parameters from large empirical datasets of dividing cells. (pnas.org)
Cell division control couples growth and division, influencing most aspects of cellular physiology ( 1 ). (pnas.org)
Cells can only reach a certain size due to a lack of balanced growth between their parts, so they have to divide once they reach a certain point. (reference.com)
By combining discoveries about the growth signals that bombard the cell from the outside with knowledge of the internal machinery that orchestrates growth, scientists hope to form a complete and finely detailed portrait of the dividing cell. (nytimes.com)
After growth, cell division by mitosis allows for continual construction and repair of the organism. (wikipedia.org)
During G 2 , the cell undergoes the final stages of growth before it enters the M phase, where spindles are synthesized. (wikipedia.org)
G1 is a time of growth for the cell. (wikipedia.org)
During G2, the cell undergoes the final stages of growth before it enters the M phase. (wikipedia.org)
Along with cell shape changes, cell rearrangements, apoptosis and growth, oriented cell division modifies the geometry and topology of live tissue in order to create new organs and shape the organisms. (wikipedia.org)
Cell division has three purposes for an organism: reproduction, growth and maintenance. (reference.com)
Microbial population growth is typically measured when cells can be directly observed, or when death is rare. (mendeley.com)
Here we introduce a new method (distributed cell division counting, DCDC) that uses the accurate segregation at cell division of genetically encoded fluorescent particles to measure microbial growth rates. (mendeley.com)
Each component of the telomerase complex was studied during cell growth and division in yeast used to make wine and bread. (ibtimes.co.uk)
In this stem cell from bone marrow are injected into a recipient after treating them with growth factor. (medindia.net)
As the number of cycles increases, the number of cells jumps drastically, making it hard to visualize the growth rate. (dummies.com)
During the G 2 period of growth, materials for the next mitotic division are prepared. (cliffsnotes.com)
The researchers say their findings, described in a pair of papers published in the journals eLife (" Biochemical reconstitution of branching microtubule nucleation ") and Nature Communications (" Phase separation of TPX2 enhances and spatially coordinates microtubule nucleation "), are a key step toward recreating the entire cell division machinery and could lead to new therapies aimed at preventing the growth of cancer cells. (genengnews.com)
Furthermore, the proliferation and growth of these organisms is based on the ability of each cell to divide into two daughter cells. (mpg.de)
Cells carry on the many functions needed to sustain life, including cell growth and development. (nsta.org)
The Cell Division and Differentiation Enhanced E-boo*k explores these cellular processes for growth and development, including the selective expression of specific genes, which allow for the differentiation and specialization of cells. (nsta.org)
We use Drosophila to unveil the basic principles that govern cell proliferation and malignant growth. (irbbarcelona.org)
The molecular basis of the contribution of germline functions to malignant growth in Drosophila somatic cells " (ONCOGERM), cofinanciado por el Ministerio de Economía, Industria y Competitividad - Agencia Estatal de Investigación y el Fondo Europeo de Desarrollo Regional (FEDER) de la Unión Europea. (irbbarcelona.org)
Targeting cell division is an attractive approach to slowing or preventing cancer growth. (fiercebiotech.com)
Researchers from Sweden and the U.K. have devised a new method to curb cancer growth by shutting down a single enzyme and stopping cells from dividing. (fiercebiotech.com)
Attacking cell division to slow cancer growth is a popular idea, for the simple reason that the abnormal growth of cells is the very definition of cancer. (fiercebiotech.com)
In cooperation with various institutes for material research we are investigating how biomaterials, surface topography, and elasticity impact on growth and differentiation of stem cells. (ukaachen.de)

When cells divide, two daughter cells are produced from one mother cell. (encyclopedia.com)
Mitosis is the process of cellular division that produces identical daughter cells from one mother cell. (encyclopedia.com)
Cells reproduce by splitting and passing on their genes (hereditary information) to Daughter cells. (bookrags.com)
New Haven, Conn. -- Time-lapse videos and computer simulations provide the first concrete molecular explanation of how a cell flexes tiny muscle-like structures to pinch itself into two daughter cells at the end of each cell division, according to a report in Science Express. (eurekalert.org)
Living cells divide into two daughter cells to reproduce themselves. (eurekalert.org)
The band then squeezes the cell into two so that two new daughter cells are formed. (innovations-report.com)
Cell division is the process whereby the two daughter cells are separated. (innovations-report.com)
Cell division is the process by which a parent cell divides into two or more daughter cells. (wikipedia.org)
7) is 2 daughter cells part of phase? (smore.com)
Cell division orientation is the direction along which the new daughter cells are formed. (wikipedia.org)
The enzyme was previously known only for its involvement in cell division, or mitosis, a process that involves the creation of two daughter cells from one parental cell. (medicalnewstoday.com)
A cleavage furrow begins to separate a dividing cell into daughter cells. (hopkinsmedicine.org)
In eukaryotic organisms, mitosis results in two daughter cells with identical copies of the parent cell DNA. (abpischools.org.uk)
in animal cells the cleavage furrow continure pinching together and eventually drawing together completely separating the cell into two distinct daughter cells. (flashcardmachine.com)
When a cell divides into two daughter cells, it must replicate its entire genome and transcribe part of it to make new proteins. (eurasiareview.com)
The two most important are S-phase when the cell's DNA is duplicated or replicated, and mitosis when the duplicated DNA is divided equally between the two daughter cells. (news-medical.net)
From bacteria to humans, all forms of life are based on the capacity of one cell to divide into two or more identical daughter cells. (healthcanal.com)
One cell replicates itself and splits into two daughter cells, enabling an organism to develop, grow, and replace cells in its body. (icr.org)
Max Planck scientists uncover a novel and generic mechanism for the division of artificial cells into two daughter cells. (mpg.de)
The success of life on earth is based on the amazing ability of living cells to divide themselves into two daughter cells. (mpg.de)

The primary concern of cell division is the maintenance of the original cell's genome . (wikipedia.org)
In the long run, a full overview of all the cell's proteins will allow us to see how different important processes of life, like cell division and cell death for example, are linked to one another. (europa.eu)

Second, the cytoplasm (the rest of the content of the cell) is divided. (encyclopedia.com)
African clawed frog (Xenopus laevis) egg-extract preparation involves collecting unfertilized eggs, crushing them, and separating out fractions of the cytoplasm through centrifugation, a process that divides membranes, organelles and cytoplasm by density. (phys.org)
To maintain a healthy balance of cells in the body, it is important that before cells divide they are the right size with plenty of cytoplasm and replicated organelles, that the DNA has replicated and is error free (or any errors have been repaired) and that once mitosis gets under way, the pairs of chromatids are attached to the spindle in the correct positions by the centromere. (abpischools.org.uk)

Anaphase B is just one part of the complex molecular choreography that is cell division. (redorbit.com)
He wanted to understand what happens during Anaphase B. So his team, led by postdoctoral fellow Chuanhai Fu, PhD, began systematically mutating molecular motors in the fission yeast, Schizosaccharomyces pombe and then clocking each mutant's cell division. (redorbit.com)
Only in cells containing mutant Klp9p was Anaphase B significantly slower. (redorbit.com)
Now, however, "we have a very detailed and complete description of four molecules" -- Klp9p, Ase1p, Cdc2p, and Clp1p "" each playing a role in one aspect of cellular division, Anaphase B. (redorbit.com)

Flemming's diagram of eukaryotic cell division (1888). (visionlearning.com)

The 2001 Nobel prize for physiology or medicine has been awarded for research on the molecular elements that control cell division. (newscientist.com)
And lately, through an extraordinary convergence of research from a broad spectrum of disciplines, scientists have made enormous progress in unraveling the pivotal molecular events that control cell division. (nytimes.com)
Working in yeast, the C. elegans worm and human cells, Cheeseman has helped to identify dozens of the kinetochore's molecular components and their specific roles. (news-medical.net)
Through its research, CohesinMolMech (Molecular mechanisms of cohesin-mediated sister chromatid cohesion and chromatin organization) aims to advance our understanding of cell division, chromatin structure and gene regulation. (europa.eu)
In addition, vesicle and cell membranes have essentially the same molecular architecture and consist of molecular bilayers with two molecular leaflets that define the two sides of the membranes: the inner leaflet is exposed to the interior, the outer leaflet to the exterior solution. (mpg.de)
We have been watching cells divide for more than 100 years, but we continue to seek to understand the molecular mechanisms involved. (nanowerk.com)
For example, stem cells divide asymmetrically, while most other cells divide symmetrically, and we still do not understand these differences in molecular terms. (nanowerk.com)
Our research focusses on molecular mechanisms that regulate human stem cells, particularly hematopoietic stem cells, mesenchymal stem cells, and induced pluripotent stem cells. (ukaachen.de)
We are working on optimized culture conditions and definition of molecular markers for quality control of mesenchymal stem cells. (ukaachen.de)
Aging of the organism as well as replicative senescence during culture expansion of stem cells is associated with various functional and molecular changes. (ukaachen.de)

Scientists have long studied aspects of how cells actually make this division -- the structure of the cellular machinery, how it assembles and how the machine works. (eurekalert.org)
The paired proteins seem to work by altering the shapes and duties of a string of other proteins in the cell, and scientists have identified many of those target proteins. (nytimes.com)
Scientists have now learned much more about the proteins involved and their behavior, and yet a central mystery remains: How does the cell signal where the furrow should be? (phys.org)
The latest cell research engaged in by scientists has helped immensely in finding a possible cure for cancer. (i4u.com)
Cell structure has aided scientists in finding the ins and outs of cancer and cancerous growths in humans. (i4u.com)
Scientists have been looking at cells since the 17th Century and so to find something that no-one has seen before is amazing. (i4u.com)
The scientists published their study in the journal Developmental Cell . (brightsurf.com)
By controlling the enzyme telomerase which directs the division, scientists now hope to be able to delay or trigger cell division. (ibtimes.co.uk)
Scientists at Salk Institute have found a cellular switch that could be controlled to encourage cells to divide and generate in old age, while preventing some others like cancer cells from dividing. (ibtimes.co.uk)
Scientists at the Oklahoma Medical Research Foundation have discovered a way in which cells duplicate themselves accurately and completely. (journalrecord.com)
The Indian Council of Medical Research and the Department of Biotechnology have jointly formulated guidelines for stem cell research and therapy to help experts and scientists working in the field conduct research responsibly and ethically sensitive manner. (medindia.net)
While up to now most research laboratories have focused on single proteins in living cells, scientists working on the EU-funded iNEXT and CohesinMolMech projects have taken a more comprehensive approach. (europa.eu)
Scientists at the Max Planck Institute of Colloids and Interfaces, Potsdam, and at the Max Planck Institute for Polymer Research, Mainz, have now achieved unprecedented control over these shape transformations and the resulting division process by anchoring low densities of proteins to the artificial cell membranes. (mpg.de)
Scientists in the preceding years had already been seeing faint structures in cells , but their dyes were not good enough to reveal what any of these structures did. (visionlearning.com)
Throughout the 19th century, as microscopes developed, scientists had been seeing clues of structures in dividing cells of eukaryotes . (visionlearning.com)
Scientists at the Oxford Institute for Radiation Oncology and Cancer Research UK created radiation-carrying gold nanoparticles that target cell division by entering cells and shutting down telomerase. (fiercebiotech.com)

In one-celled organisms like yeast, each cell division yields a new creature. (eurekalert.org)
We found that fission yeast cells assemble their contractile ring using a 'search, capture, pull and release' mechanism," said Pollard. (eurekalert.org)
Future work will involve testing the concepts learned from fission yeast in other cells to learn if the mechanism is universal," said Pollard. (eurekalert.org)
This link between Bub1, histone H2A phosphorylation, and shugoshin is conserved in budding yeast and mammalian cells. (sciencemag.org)
Some bacteria and fungi, like yeast, form new cells through budding. (dummies.com)

A structure called a cleavage furrow is crucial to producing new cells through cell division. (hopkinsmedicine.org)
Successful cell division hangs on the formation of a dip called a cleavage furrow, a process that has remained mysterious. (hopkinsmedicine.org)

In single-cell organisms like protists, mitosis produces two whole organisms. (encyclopedia.com)
Why are cells important for living organisms? (reference.com)
Cells are important for living organisms because cells are the basic building blocks from which all organisms are created. (reference.com)
On a larger scale, mitotic cell division can create progeny from multicellular organisms, such as plants that grow from cuttings. (wikipedia.org)
Mitotic cell division enables sexually reproducing organisms to develop from the one-celled zygote , which itself was produced by meiotic cell division from gametes . (wikipedia.org)
Whenever multicellular organisms grow, more cells are required. (abpischools.org.uk)
A novel connection between primordial organisms and complex life has been discovered, as new evidence sheds light on the evolutionary origins of the cell division process that is fundamental to complex life on Earth. (brightsurf.com)
Observing the cell in its native state: Imaging subcellular dynamics in multicellular organisms," bioRxiv , doi:10.1101/243352, 2018. (the-scientist.com)
All living organisms on earth are built up from individual cells. (mpg.de)

The discovery reveals that, when disturbed, this process could contribute to cancer or other diseases by failing to properly control the steps and timing of cell division, the researchers say. (medindia.net)
The comings and goings of the sugar on proteins seem to be important controllers of cell division, say the researchers. (medindia.net)
The researchers' next steps are to examine select proteins modified by O-GlcNAc and found at locations important for various steps in cell division to figure out why an imbalance of O-GlcNAc on the cells' proteins has such a dramatic effect on the process. (medindia.net)
With the use of immunofluorescence the researchers determined the location of these proteins in the cell and in doing so discovered that three proteins play a crucial role in the cell division of Sulfolobus acidocaldarius. (innovations-report.com)
UT Southwestern Medical Center and California researchers provide the first report that an enzyme previously known solely for its role in cell division also acts as an on-off switch in the innate immune system -- the body's first defense against infection. (medicalnewstoday.com)
Researchers are in desperate need of single-cell analysis techniques and those that allow the isolation of high-value T-cells for research and development. (news-medical.net)
This cell-free system has two huge advantages: It expands the scale of the furrow-building events, making them easier to see, and it gives the researchers an easy way to manipulate the proteins involved. (phys.org)
However, when researchers at California Institute of Technology observed this step using their new technique, what they saw was not the usual cell division. (photonics.com)
The researchers are now using the same method to try to image human cells. (photonics.com)
In the new study, which is a continuation of the previous findings in the CCS, the researchers have primarily done tests on different types of cancer cells including bone, cervical and colon cancer. (news-medical.net)
Researchers from the Ludwig Institute for Cancer Research at the University of California, San Diego School of Medicine, have uncovered a remarkable property of the contractile ring, a structure required for cell division. (brightsurf.com)
Researchers at the University of Liverpool have resolved the debate over the mechanisms involved in the shut-down process during cell division in the body. (brightsurf.com)
Researchers report in bioRxiv that they combined lattice light sheet microscopy, which increases the speed of image acquisition and reduces phototoxic damage to cells, with two-channel adaptive optics to image multiple cellular processes in vivo. (the-scientist.com)
As the project's researchers explain in a paper published in the journal 'Nature', the model can also be used to study the role that proteins play in other cellular functions, such as cell death or the metastasis of cancer cells. (europa.eu)
Reporting in the journal Cell , researchers found that a particular enzyme called Cdk operates as a master oscillator, undergoing rhythmic periods of activity. (icr.org)
It turns out, however, that controlled division can be achieved in a much simpler way, as researchers at the Max Planck Institute of Colloids and Interfaces, Potsdam, and at the Max Planck Institute for Polymer Research, Mainz, have recently demonstrated for artificial cells. (mpg.de)
In addition to demonstrating the division of artificial cells, the researchers around Reinhard Lipowsky also identified the novel mechanism, by which this constriction force can be controlled in a systematic manner. (mpg.de)

Cell Division Cell division is the process by which an organism grows or replaces damaged tissue. (bookrags.com)
Cell Division Cell division is the process where a single living cell splits to become two or more distinct new cells. (bookrags.com)
Most of the time when people refer to "cell division," they mean mitosis, the process of making new body cells. (medlineplus.gov)
The "help" which Topo2 receives comes from the microtubules, a type of tiny wire that makes up part of the mitotic spindle, a structure similar to a rugby ball that is created when the cell begins the process of duplication and division. (eurekalert.org)
The process is akin to two children dividing up their Halloween candy: collect your candy, pile it in the middle, and divide it into two equal portions. (redorbit.com)
Chlamydiae divide by a unique MreB-dependent polarized cell division process. (asm.org)
Studying the process of cell division in Sulfolobus acidocaldarius could therefore lead to new insights into the processes involving ESCRT proteins, such as HIV particle release. (innovations-report.com)
Mitosis: The Amazing Cell Process that Uses Division to Multiply! (youtube.com)
In females, the process is called oogenesis because it produces egg cells, also known as ova. (reference.com)
The majority of cells that build the nervous system of animals are generated early in embryonic development in a process called neurogenesis. (nih.gov)
The cell has to monitor and control its activities to coordinate with the cell division process. (news-medical.net)
Phys.org) -The process of cell division is central to life. (phys.org)
They then mimicked fertilization and added labeled antibodies or proteins to visualize the self-organization of structures required for the cell division process, using fluorescence microscopy in ways that aren't possible with actual living cells in tissue cultures. (phys.org)
Now, Professor Carl-Philipp Heisenberg and his team at the Institute of Science and Technology Austria discovered how mechanical tension from surrounding tissue influences the division process. (brightsurf.com)
A study led by the Universitat Autònoma de Barcelona has determined the three-dimensional structure of certain proteins linked to the correct functioning of the cell division process: The LC8 and Nek9 pair. (brightsurf.com)
She will grow and develop as new cells are formed by the process of mitosis (cell division). (abpischools.org.uk)
Bacterial cell division has been studied mainly in model systems such as Escherichia coli and Bacillus subtilis , where it is described as a complex process with the participation of a group of proteins which assemble into a multiprotein complex called the septal ring. (scielo.br)
Cell division in bacteria is a complex process involving the coordinated participation of a group of proteins which assemble at the division site into a multiprotein complex called the septal ring (for reviews see Errington et al . (scielo.br)
Binary fission, which is used by many bacteria, is a process in which the growing cell first replicates its DNA and then the cell wall constricts, dividing the cell into two. (dummies.com)
Their role in cell division is also especially important, since they control all parts of the process, from beginning to end. (europa.eu)
By entering any combination of up to seven proteins, users will be able to see the relevant cell division process in real time. (europa.eu)
How do cells keep all of this straight, and how do they continually repeat the process with such precision? (icr.org)
The success of the process is crucial for any dividing cell, which includes all cells and therefore all living systems. (icr.org)
1 Cdk activates a host of subsidiary oscillators, each one in charge of activating a separate but necessary process at a distinct phase of cell division. (icr.org)
We have found that neural stem cells originate tumours when the delicately balanced process of self-renewing asymmetric division is disrupted. (irbbarcelona.org)
They were part of the life process of the cells . (visionlearning.com)
It's important to remember that the process of cell division is cyclical, with one phase feeding into the next. (visionlearning.com)
The discovery of this mechanism is a significant breakthrough in advancing knowledge about the cell division process. (nanowerk.com)

Cancer cells are able to replicate by overcoming the normal controls of cell division. (abpischools.org.uk)

Dexamethasone suppresses HMBA-mediated MELC differentiation, but MELC retain a memory for their exposure to HMBA since, on transfer from culture with HMBA and dexamethasone to medium without additions, a portion of the cells express characteristics of terminal differentiation. (pnas.org)
We characterize how epigenetic changes are acquired during differentiation and how cell fate is regulated by external stimuli. (ukaachen.de)
Cellular differentiation is governed by epigenetic changes - and hence the epigenetic makeup is ideally suited to characterize cells. (ukaachen.de)

Pairs of sister chromatids split and are pulled to opposite sides of the cell by the microtubules. (encyclopedia.com)
Microtubules pull each homologue to opposite sides of the cell. (encyclopedia.com)
He also has started to define how the attachments between kinetochores and spindle microtubules are regulated throughout cell division. (news-medical.net)
The microtubules that are part and parcel of the inner "bone-work" of the cell seem to be involved here. (i4u.com)
Centrosomes organize microtubules, which are structures in the cell that many important anti-cancer drugs target. (scienceblog.com)

Prophase is the first stage of division. (wikipedia.org)

A decline in stem cell function has been proposed to contribute to tissue ageing, although the underlying mechanism is poorly understood. (nature.com)
The simulations show that cells use reaction rates that are nearly ideal to make this mechanism work on the time scale of the events in the cells. (eurekalert.org)
A Swedish research group, partly financed by NWO, has discovered a new mechanism for cell division in a microorganism found in extremely hot and acidic conditions. (innovations-report.com)
The new mechanism for cell division was discovered in Sulfolobus acidocaldarius, a microorganism found in hot springs in Yellowstone National Park. (innovations-report.com)
And this is just one mechanism, tightly linked with many other major cell processes, that ensures cell division is properly regulated. (icr.org)
In this way, a simple and generic mechanism for the division of artificial cells has been identified. (mpg.de)

Some of the proteins in the new type of cell division are similar to proteins in other eukaryotes that have a completely different function. (innovations-report.com)

Mycoplasmas are cell wall-less bacteria presenting a reduced genome. (scielo.br)

How does cell division provide for continuity of life processes in an individual and in a species? (prezi.com)
FtsH and FtsY, even if they were initially identified by mutants that showed a filamentation phenotype, they are in fact involved in general processes that have pleiotropic effects on cell division (Tomoyasu et al . (scielo.br)
Learn more about the biological processes of cell division. (alison.com)
This course about cell division will explain the complex processes of cell division in detail. (alison.com)
To make this possible, hundreds of different proteins work together in a single cell, driving its various processes. (europa.eu)
Such evolutionary conservation from flies to humans is expected for processes as fundamental as cell division, he explained. (nanowerk.com)
In fact, all cancers are characterised by unchecked cell division, and the underpinning processes are potential targets for therapeutic interventions that prevent cancer onset and spread. (nanowerk.com)
But before we get there, we must continue to expand our knowledge about the basic processes and signals involved in normal cell division to understand how they can go awry, or how they can be exploited. (nanowerk.com)

A mass of abnormal cells which keep multiplying in an uncontrolled way. (abpischools.org.uk)
This abnormal cell division causes a tumor to develop. (eurasiareview.com)
The health span of supercentenarians might be partly explained by the expansion of T cells that kill infected or abnormal cells. (pnas.org)
In the case of cancer, this means that the cancer cell has the potential to become even more abnormal due to the new mutations,' Ying Liu explains. (news-medical.net)

These proteins localize to specific parts of the cell and regulate cell division from there. (wur.nl)
Several factors could regulate cell shape and therefore orientation of cell division. (wikipedia.org)

Two 18 x 24" charts detail mitotic and meiotic cell division in both plants and animals. (carolina.com)

The 10 million Euro, five-year scientific project is a joint research effort, bringing together the expertise of thirteen European institutions and companies to generate a comprehensive mathematical understanding of mitotic cell division. (innovations-report.com)
Mitotic cell division does not take place at random. (abpischools.org.uk)

Sex cells, such as eggs and sperm, are only created through specialized cell division. (reference.com)
The sex cells (ova and sperm) that join together to form a new unique diploid cell in sexual reproduction. (abpischools.org.uk)

Otherwise, they will not be able to separate during cell division, and the DNA within could be cut or divided badly, which might lead to cell death or harmful mutations - and possibly cancer. (eurekalert.org)
If MiDAS cannot take place, it leads to cell death or mutations in the surviving cells. (news-medical.net)

Blood stem cell transplantation and stem cell treatment in India, the possibilities and challenges ahead and the need for cord blood banks were discussed at a Jeevan oration meet in Chennai. (medindia.net)
Preferred Term is Hematopoietic stem cell transplantation. (medindia.net)
For decades, cord blood donation has served an important role in facilitating stem cell transplantation for the treatment of various blood and immune disorders. (stanford.edu)
Spinal cord injury has been recognized as one of the conditions for which stem cell transplantation might be beneficial. (wingsforlife.com)

While binary fission many be the means of division by most prokaryotes, there are alternative manners of division, such as budding, that have been observed. (wikipedia.org)

Isolated midbodies are also pictured in green around the cells to show the organelles in more detail. (wisconline.com)

the replicated pairs of centrioles migrate to opposite poles of the cell. (flashcardmachine.com)

The chemical is called putrescine (1,4 diaminobutane), a malodorous organic compound within the polyamine family-a group of molecules already known to play a crucial role in important functions like cell division. (discovermagazine.com)

dramatically increase the activity of this gene when they regenerate, allowing stem cells to maintain their telomeres as they divide to replace missing tissues. (slashdot.org)
Telomeres also help divvy-up the workload among stem cells so the most eager doesn't monopolize the work. (slashdot.org)
It rebuilds telomeres and allows cells to divide indefinitely. (ibtimes.co.uk)

In humans and other multicellular species, cell division creates an adult from an embryo. (eurekalert.org)

Each cell contains a pair of sister chromatids. (encyclopedia.com)
Migration of chromatids to cell poles mediated by the kinetochore. (prezi.com)

NRLP3 is one of several inflammasomes - multiprotein structures in disease-fighting white blood cells - the first of which was identified less than 15 years ago. (medicalnewstoday.com)
Unfortunately, the dyes killed the cells, and since the structures under the microscope were difficult to see as it was, Flemming's forerunners weren't sure they were seeing anything characteristic of a live, functional cell. (visionlearning.com)

But many more years of work are required before the team can create a data set for the 600 or so proteins that drive mitosis in human cells. (europa.eu)

Without Cdk and its associate enzymes comprising what the authors call a 'phase-locking model,' cell division would not work. (icr.org)

Normal cell division is called mitosis, and this results in two identical cells. (reference.com)

In both cases, neuronal cells are derived from polarized progenitor cells that divide asymmetrically. (nih.gov)
A) Culture expansion of hematopoietic stem and progenitor cells (CD34+ cells, HSCs) on plastic or mesenchymal stromal cells (MSCs). (ukaachen.de)
Cancer initiating cells are often derived from stem and progenitor cells. (ukaachen.de)

That information will in turn permit them to better understand cell division gone awry, the hallmark of cancer. (nytimes.com)
Clarke MF, Fuller M (2006) Stem cells and cancer: two faces of eve. (springer.com)
Dick JE (2008) Stem cell concepts renew cancer research. (springer.com)
Thus cancer involves a glitch in cell division. (i4u.com)
Cancer is a disease of the cells, which are the body's basic building blocks. (cancervic.org.au)
We were investigating which proteins help cancer cells to use MiDAS. (news-medical.net)
We believe that this RTEL1 function is critical for any cancer cells that rely on MiDAS, which is more than 80 percent of the known cancer types based on our knowledge. (news-medical.net)
Therefore, we can use this to design drugs to inhibit RTEL1 and hopefully selectively kill cancer cells,' says Ying Liu. (news-medical.net)
In this interview, News-Medical speaks to Dr. Cristina Branco from Breast Cancer Now about the spread of breast cancer cells to the lungs. (news-medical.net)
Understanding how the contractile ring works to divide the cell may facilitate development of therapies to prevent uncontrolled cell division in cancer. (brightsurf.com)
The idea that a failure of proper cell division produces genomic instability and promotes the development of cancer was first proposed by German biologist Theodor Boveri in 1915. (brightsurf.com)
Cancer is a disease that originates in our own cells. (abpischools.org.uk)
Cancer cells may spread from the original (primary) tumour to form new (secondary) tumours throughout the body. (abpischools.org.uk)
This resource looks at how cancer cells develop, the causes of cancer and how treatments are used to tackle cancer. (abpischools.org.uk)
Sometimes mitosis can go wrong and cause cancer cells to develop. (abpischools.org.uk)
The new 4D model was used to integrate data on fluorescently knocked-in mitotic proteins taken from HeLa cells, an immortal line of human cancer cells commonly used in scientific research. (europa.eu)
Elevated TPX2 levels lead to both aberrant microtubule assembly in cells and poor outcomes in cancer patients. (genengnews.com)
Ultimately, this could help the rational design of more specific therapies to inhibit the division of cancer cells, ideally without affecting the healthy cells that are dividing at the same time, Hickson said. (nanowerk.com)
In cancer, this breakdown is sabotaged, allowing the cells to multiply freely. (fiercebiotech.com)

Anatomy52

Organisms26

Diseases2

Chemicals and Drugs78

Analytical, Diagnostic and Therapeutic Techniques and Equipment24

Phenomena and Processes84

Disciplines and Occupations1

Technology, Industry, Agriculture3

Information Science6

Health Care1

Epidermis

Meiosis

Oncolytic adenovirus

Cdc25

Syntelic

Centrosome cycle

Aurora A kinase

PLK1

Light sheet fluorescence microscopy

John Graham White

Arbacia punctulata

Transplacental carcinogenesis

Frank Uhlmann

Cln3

Compartment (development)

WPP domain

POLD1

Amy Gladfelter

Breast cancer classification

Fetal tissue in vaccines

APC/C activator protein CDH1

SV40 large T antigen

Immunosuppressive drug

Balanced-growth equilibrium

Lactoylglutathione lyase

Neuron - Simple English Wikipedia, the free encyclopedia

Carboxyfluorescein succinimidyl ester

Cancer

Embryophyte

Plasma cell

Pol Pot

Clave (rhythm)

Elastina - Wikipédia, a enciclopédia livre

Vinca alkaloid

Group 3 element

Leaf

Ebola

Acne

Octopus

Caulobacter crescentus

Tüvirakud - Vikipeedia, vaba entsüklopeedia

Cultured neuronal network

Tornado

Pinophyta

Alkali metal

Brain tumor

Antiandrogen

Brassicaceae

Cold fusion

Tonsil

STS-47

G1 phase

Prokaryotic DNA replication

Nigel Unwin

Papillary tumors of the pineal region

Interferon

CDC25C

ABL (gene)

Pyrrolobenzodiazepine

Cell Division | Encyclopedia.com

Cell division

Category:Cell division - Wikimedia Commons

How do cells divide?: MedlinePlus Genetics

Unraveling cell division | EurekAlert! Science News

Cell division discoveries get Nobel prize | New Scientist

Newly Discovered Mechanism in Cell Division - Redorbit

Centrosome misorientation reduces stem cell division during ageing | Nature

Concerted control of Escherichia coli cell division | PNAS

Why do cells divide? | Reference.com

Cell Division Gizmo : ExploreLearning

Cell Division

Cell Division

How molecular muscles help cells divide | EurekAlert! Science News

Biologists Unravel Key Events of Cell Division - The New York Times

Sugar Helps Control Cell Division

cell division | Journal of Bacteriology

Proteins strangle cell during division

Cell Division Charts | Carolina.com

The Art of Cell Division

cell division Archives - Discoblog : Discoblog