Growth processes that result in an increase in CELL SIZE.
The quantity of volume or surface area of CELLS.
Proteins found in plants (flowers, herbs, shrubs, trees, etc.). The concept does not include proteins found in vegetables for which VEGETABLE PROTEINS is available.
The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION.
Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.
General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).
Abnormal enlargement or overgrowth of the gingivae brought about by enlargement of existing cells.
Non-inflammatory enlargement of the gingivae produced by factors other than local irritation. It is characteristically due to an increase in the number of cells. (From Jablonski's Dictionary of Dentistry, 1992, p400)
Excessive growth of the gingiva either by an increase in the size of the constituent cells (GINGIVAL HYPERTROPHY) or by an increase in their number (GINGIVAL HYPERPLASIA). (From Jablonski's Dictionary of Dentistry, 1992, p574)
'Gingival diseases' is a general term for conditions affecting the soft tissues surrounding and supporting the teeth, primarily characterized by inflammation, bleeding, redness, or swelling, which can progress to periodontal disease if left untreated.
Oral tissue surrounding and attached to TEETH.
Inflammation of gum tissue (GINGIVA) without loss of connective tissue.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)

A portrait of AKT kinases: human cancer and animal models depict a family with strong individualities. (1/461)

More than a decade after their discovery, the three AKT kinase family members have emerged as central players in the signaling cascades that regulate cell growth, proliferation, survival and various aspects of intermediary metabolism. The mechanisms of activation of AKT kinases have been defined in relatively precise terms and new substrates are currently being validated in vivo. However, it is presently unclear whether AKT1, AKT2 and AKT3 are functionally redundant or whether each one performs specific functional role(s). In this review, we will summarize the signaling properties and highlight the specificities of AKT kinases that have emerged from the study of human cancer and animal models. While AKT kinases are an attractive target for pharmacological intervention, knowledge of the precise individual roles of AKT family members will improve the design of highly specific AKT-based therapeutics having reduced toxicity and improved efficacy.  (+info)

Effect of ethanol on cell growth of budding yeast: genes that are important for cell growth in the presence of ethanol. (2/461)

The budding yeast Saccharomyces cerevisiae has been used in the fermentation of various kinds of alcoholic beverages. But the effect of ethanol on the cell growth of this yeast is poorly understood. This study shows that the addition of ethanol causes a cell-cycle delay associated with a transient dispersion of F-actin cytoskeleton, resulting in an increase in cell size. We found that the tyrosine kinase Swe1, the negative regulator of Cdc28-Clb kinase, is related to the regulation of cell growth in the presence of ethanol. Indeed, the increase in cell size due to ethanol was partially abolished in the SWE1-deleted cells, and the amount of Swe1 protein increased transiently in the presence of ethanol. These results indicated that Swe1 is involved in cell size control in the presence of ethanol, and that a signal produced by ethanol causes a transient up-regulation of Swe1. Further we investigated comprehensively the ethanol-sensitive strains in the complete set of 4847 non-essential gene deletions and identified at least 256 genes that are important for cell growth in the presence of ethanol.  (+info)

Overexpression of sphingosine-1-phosphate lyase or inhibition of sphingosine kinase in Dictyostelium discoideum results in a selective increase in sensitivity to platinum-based chemotherapy drugs. (3/461)

The efficacy of the chemotherapy drug cisplatin is often limited due to resistance of the tumors to the drug, and increasing the potency of cisplatin without increasing its concentration could prove beneficial. A previously characterized Dictyostelium discoideum mutant with increased resistance to cisplatin was defective in the gene encoding sphingosine-1-phosphate (S-1-P) lyase, which catalyzes the breakdown of S-1-P, an important regulatory molecule in cell function and development and in the regulation of cell fate. We hypothesized that the increased resistance to cisplatin was due to an elevation of S-1-P and predicted that lowering levels of S-1-P should increase sensitivity to the drug. We generated three strains that stably overexpress different levels of the S-1-P lyase. The overexpressor strains have reduced growth rate and, confirming the hypothesis, showed an expression-dependent increase in sensitivity to cisplatin. Consistently, treating the cells with D-erythro-N,N,-dimethylsphingosine, a known inhibitor of sphingosine kinase, increased the sensitivity of mutant and parent cells to cisplatin, while addition of exogenous S-1-P or 8-Br-cyclic AMP made the cells more resistant to cisplatin. The increased sensitivity of the overexpressors to cisplatin was also observed with the cisplatin analog carboplatin. In contrast, the response to doxorubicin, 5-flurouracil, or etoposide was unaffected, indicating that the involvement of the sphingolipid metabolic pathway in modulating the response to cisplatin is not part of a global genotoxic stress response. The augmented sensitivity to cisplatin appears to be the result of an intracellular signaling function of S-1-P, because D. discoideum does not appear to have endothelial differentiation growth (EDG/S1P) receptors. Overall, the results show that modulation of the sphingolipid pathway at multiple points can result in increased sensitivity to cisplatin and has the potential for increasing the clinical usefulness of this important drug.  (+info)

Dynamic balancing of the dual nature of HIF-1alpha for cell survival. (4/461)

In hypoxic cells, HIF-1alpha escapes from oxygen-dependent proteolysis and binds to the hypoxia-responsive element (HRE) for transcriptional activation of target genes involved in angiogenesis and glycolysis. We recently demonstrated that the G(1) checkpoint gene p21(cip1)is activated by HIF-1alpha with a novel mechanism that involves the HIF-1alpha PAS domains to displace Myc binding from p21(cip1) promoter. This HIF-1alpha-Myc pathway may account for up- and down-regulation of other hypoxia-responsive genes that lack the HRE. Moreover, the role of HIF-1alpha in cell cycle control indicates a dual, yet seemingly conflicting, nature of HIF-1alpha: promoting cell growth and arrest in concomitance. We speculate that a dynamic balance between the two processes is achieved by a "stop-and-go" strategy to maintain cell growth and survival. Tumor cells may adopt such scheme to evade the killing by chemotherapeutic agents.  (+info)

Coordination of cell growth and cell division: a mathematical modeling study. (5/461)

Although there is general agreement that cell growth and division are functionally coordinated, the mechanisms that link the two processes are poorly understood. In this study, we have developed a mathematical model based on current biological concepts of the signaling transduction pathways involved in cell growth, which predicts that cell growth rate is proportional to cell surface area at birth. To investigate the relationship between growth control and cell division, we then applied our mathematical model to three classic experiments measuring cycle time versus cell birth size in fission yeast and Xenopus laevis, and the cell cycle delay in mammalian cells after serum withdrawal. When coupled to a cell cycle exhibiting 'sizer' and 'timer' phases, we show that a simple model in which growth rate is proportional to the cell surface area immediately after division reproduces the experimental observations including the relationship between cycle time and birth size in fission yeast and Xenopus laevis. The model also accounts for the cell cycle delay seen in restriction point experiments performed in HeLa cells.  (+info)

Cytochemical and ultrastructural characterization of growing colonies of human embryonic stem cells. (6/461)

The morphology of human embryonic stem (ES) cells changes with their colonial growth. For a better understanding of the growth of ES cell colonies in culture, we determined their cytochemical and ultrastructural characteristics focusing on images of living cells under a phase contrast microscope. During the initial growth stages, the colonies exhibited a mosaic appearance with discernible cell-cell borders. PAS staining coupled with amylase digestion demonstrated that the bright granules and dark deposits in the cytoplasm contained glycogen. Ultrastructurally they were glycogen accumulations, and clustered open spaces associated with various amounts of glycogen. Although intercellularly heterogeneous, these structures were detectable throughout colony growth. As the colonies grew, compaction towards the centre emerged and increased, accompanied by heterogeneous increases in coarse particles with or without a halo. TUNEL showed these particles to consist at least in part of apoptotic cells/bodies. Transmission electron microscopy indicated that most apoptotic cells had been phagocytosed by intact ES cells. Spontaneous differentiation was detected occasionally in the periphery of the colonies. The presence of PAS-positive fibrous structures not susceptible to amylase digestion and laminin-immunoreactivity indicated the accumulation of extracellular matrix in the peripheral differentiated areas. These findings made it possible to determine the growth stage of human ES cell colonies.  (+info)

The mechanics of surface expansion anisotropy in Medicago truncatula root hairs. (7/461)

Wall expansion in tip-growing cells shows variations according to position and direction. In Medicago truncatula root hairs, wall expansion exhibits a strong meridional gradient with a maximum near the pole of the cell. Root hair cells also show a striking expansion anisotropy, i.e. over most of the dome surface the rate of circumferential wall expansion exceeds the rate of meridional expansion. Concomitant measurements of expansion rates and wall stresses reveal that the extensibility of the cell wall must vary abruptly along the meridian of the cell to maintain the gradient of wall expansion. To determine the mechanical basis of expansion anisotropy, we compared measurements of wall expansion with expansion patterns predicted from wall structural models that were either fully isotropic, transversely isotropic, or fully anisotropic. Our results indicate that a model based on a transversely isotropic wall structure can provide a good fit of the data although a fully anisotropic model offers the best fit overall. We discuss how such mechanical properties could be controlled at the microstructural level.  (+info)

Hedgehog and Decapentaplegic instruct polarized growth of cell extensions in the Drosophila trachea. (8/461)

The migration of cellular extensions is guided by signals from tissues with which they contact. Many axon guidance molecules regulate growth cone migration by directly regulating actin cytoskeletal dynamics. Secreted morphogens control global patterns of cell fate decisions during organogenesis through transcriptional regulation, and constitute another class of guidance molecules. We have investigated the guidance roles of the morphogens Hedgehog and Decapentaplegic during directed outgrowth of cytoplasmic extensions in the Drosophila trachea. A subset of tracheal terminal cells adheres to the internal surface of the epidermis and elongates cytoplasmic processes called terminal branches. Hedgehog promotes terminal branch spreading and its extension over the posterior compartment of the epidermis. Decapentaplegic, which is expressed at the onset of terminal branching, restricts dorsal extension of the terminal branch and ensures its monopolar growth. Orthogonal expression of Hedgehog and Decapentaplegic in the epidermis instructs monopolar extension of the terminal branch along the posterior compartment, thereby matching the pattern of airway growth with that of the epidermis.  (+info)

Cell enlargement is a process in which the size of a cell increases due to various reasons. This can occur through an increase in the amount of cytoplasm, organelles, or both within the cell. Cell enlargement can be a normal physiological response to stimuli such as growth and development, or it can be a pathological change associated with certain medical conditions.

There are several mechanisms by which cells can enlarge. One way is through the process of hypertrophy, in which individual cells increase in size due to an increase in the size of their component parts, such as organelles and cytoplasm. This type of cell enlargement is often seen in response to increased functional demands on the cell, such as in the case of muscle cells that enlarge in response to exercise.

Another mechanism by which cells can enlarge is through the process of hyperplasia, in which the number of cells in a tissue or organ increases due to an increase in the rate of cell division. While this does not result in individual cells becoming larger, it can lead to an overall increase in the size of the tissue or organ.

Cell enlargement can also occur as a result of abnormal accumulations of fluids or other materials within the cell. For example, cells may become enlarged due to the accumulation of lipids, glycogen, or other storage products, or due to the accumulation of waste products that are not properly cleared from the cell.

In some cases, cell enlargement can be a sign of a medical condition or disease process. For example, certain types of cancer cells may exhibit abnormal growth and enlargement, as can cells affected by certain genetic disorders or infections. In these cases, cell enlargement may be accompanied by other symptoms or signs that can help to diagnose the underlying condition.

Cell size refers to the volume or spatial dimensions of a cell, which can vary widely depending on the type and function of the cell. In general, eukaryotic cells (cells with a true nucleus) tend to be larger than prokaryotic cells (cells without a true nucleus). The size of a cell is determined by various factors such as genetic makeup, the cell's role in the organism, and its environment.

The study of cell size and its relationship to cell function is an active area of research in biology, with implications for our understanding of cellular processes, evolution, and disease. For example, changes in cell size have been linked to various pathological conditions, including cancer and neurodegenerative disorders. Therefore, measuring and analyzing cell size can provide valuable insights into the health and function of cells and tissues.

"Plant proteins" refer to the proteins that are derived from plant sources. These can include proteins from legumes such as beans, lentils, and peas, as well as proteins from grains like wheat, rice, and corn. Other sources of plant proteins include nuts, seeds, and vegetables.

Plant proteins are made up of individual amino acids, which are the building blocks of protein. While animal-based proteins typically contain all of the essential amino acids that the body needs to function properly, many plant-based proteins may be lacking in one or more of these essential amino acids. However, by consuming a variety of plant-based foods throughout the day, it is possible to get all of the essential amino acids that the body needs from plant sources alone.

Plant proteins are often lower in calories and saturated fat than animal proteins, making them a popular choice for those following a vegetarian or vegan diet, as well as those looking to maintain a healthy weight or reduce their risk of chronic diseases such as heart disease and cancer. Additionally, plant proteins have been shown to have a number of health benefits, including improving gut health, reducing inflammation, and supporting muscle growth and repair.

Cell division is the process by which a single eukaryotic cell (a cell with a true nucleus) divides into two identical daughter cells. This complex process involves several stages, including replication of DNA, separation of chromosomes, and division of the cytoplasm. There are two main types of cell division: mitosis and meiosis.

Mitosis is the type of cell division that results in two genetically identical daughter cells. It is a fundamental process for growth, development, and tissue repair in multicellular organisms. The stages of mitosis include prophase, prometaphase, metaphase, anaphase, and telophase, followed by cytokinesis, which divides the cytoplasm.

Meiosis, on the other hand, is a type of cell division that occurs in the gonads (ovaries and testes) during the production of gametes (sex cells). Meiosis results in four genetically unique daughter cells, each with half the number of chromosomes as the parent cell. This process is essential for sexual reproduction and genetic diversity. The stages of meiosis include meiosis I and meiosis II, which are further divided into prophase, prometaphase, metaphase, anaphase, and telophase.

In summary, cell division is the process by which a single cell divides into two daughter cells, either through mitosis or meiosis. This process is critical for growth, development, tissue repair, and sexual reproduction in multicellular organisms.

Cell differentiation is the process by which a less specialized cell, or stem cell, becomes a more specialized cell type with specific functions and structures. This process involves changes in gene expression, which are regulated by various intracellular signaling pathways and transcription factors. Differentiation results in the development of distinct cell types that make up tissues and organs in multicellular organisms. It is a crucial aspect of embryonic development, tissue repair, and maintenance of homeostasis in the body.

Hypertrophy, in the context of physiology and pathology, refers to an increase in the size of an organ or tissue due to an enlargement of its constituent cells. It is often used to describe the growth of muscle cells (myocytes) in response to increased workload or hormonal stimulation, resulting in an increase in muscle mass. However, hypertrophy can also occur in other organs such as the heart (cardiac hypertrophy) in response to high blood pressure or valvular heart disease.

It is important to note that while hypertrophy involves an increase in cell size, hyperplasia refers to an increase in cell number. In some cases, both hypertrophy and hyperplasia can occur together, leading to a significant increase in the overall size and function of the organ or tissue.

Gingival hypertrophy is a condition characterized by an abnormal enlargement or overgrowth of the gingiva (gum tissue). This can be caused due to various reasons such as inflammation from poor oral hygiene, certain medications like phenytoin and cyclosporine, or systemic conditions such as pregnancy, leukemia, and vitamin C deficiency.

The enlarged gums may appear swollen, red, and bleed easily. They can also cover the teeth, making cleaning difficult, which can further worsen the inflammation. Depending on the cause, treatment options may include improving oral hygiene, changing medications, or undergoing surgical procedures to remove the excess tissue.

Gingival hyperplasia is a condition characterized by an abnormal growth or enlargement of the gingiva (gum tissue). This condition can be caused by various factors, including bacterial infection, certain medications (such as phenytoin, cyclosporine, and nifedipine), systemic diseases (such as leukemia, vitamin C deficiency, and Crohn's disease), and genetic disorders.

The enlarged gum tissue can be uncomfortable, irritated, and prone to bleeding, especially during brushing or flossing. It may also make it difficult to maintain good oral hygiene, which can increase the risk of dental caries and periodontal disease. Treatment for gingival hyperplasia typically involves improving oral hygiene, controlling any underlying causes, and in some cases, surgical removal of the excess tissue.

Gingival overgrowth, also known as gingival hyperplasia or hypertrophy, refers to an abnormal enlargement or growth of the gum tissue (gingiva) surrounding the teeth. This condition can be caused by various factors, including poor oral hygiene, certain medications (such as phenytoin, cyclosporine, and calcium channel blockers), genetic predisposition, and systemic conditions like vitamin C deficiency or leukemia.

Gingival overgrowth can lead to several complications, such as difficulty in maintaining oral hygiene, which may result in periodontal disease, tooth decay, bad breath, and potential loss of teeth. In some cases, the enlarged gum tissue may also cause discomfort or pain during speaking, chewing, or brushing. Treatment for gingival overgrowth typically involves improving oral hygiene, adjusting medications if possible, and undergoing surgical procedures to remove the excess gum tissue. Regular dental check-ups and cleanings are essential in managing and preventing this condition.

Gingival diseases are infections or inflammations that affect the gingiva, which is the part of the gum around the base of the teeth. These diseases can be caused by bacteria found in dental plaque and can lead to symptoms such as redness, swelling, bleeding, and receding gums. If left untreated, gingival diseases can progress to periodontal disease, a more serious condition that can result in tooth loss. Common types of gingival diseases include gingivitis and periodontitis.

Gingiva is the medical term for the soft tissue that surrounds the teeth and forms the margin of the dental groove, also known as the gum. It extends from the mucogingival junction to the base of the cervical third of the tooth root. The gingiva plays a crucial role in protecting and supporting the teeth and maintaining oral health by providing a barrier against microbial invasion and mechanical injury.

Gingivitis is a mild form of gum disease (periodontal disease) that causes irritation, redness, swelling and bleeding of the gingiva, or gums. It's important to note that it is reversible with good oral hygiene and professional dental treatment. If left untreated, however, gingivitis can progress to a more severe form of gum disease known as periodontitis, which can result in tissue damage and eventual tooth loss.

Gingivitis is most commonly caused by the buildup of plaque, a sticky film of bacteria that constantly forms on our teeth. When not removed regularly through brushing and flossing, this plaque can harden into tartar, which is more difficult to remove and contributes to gum inflammation. Other factors like hormonal changes, poor nutrition, certain medications, smoking or a weakened immune system may also increase the risk of developing gingivitis.

An encyclopedia is a comprehensive reference work containing articles on various topics, usually arranged in alphabetical order. In the context of medicine, a medical encyclopedia is a collection of articles that provide information about a wide range of medical topics, including diseases and conditions, treatments, tests, procedures, and anatomy and physiology. Medical encyclopedias may be published in print or electronic formats and are often used as a starting point for researching medical topics. They can provide reliable and accurate information on medical subjects, making them useful resources for healthcare professionals, students, and patients alike. Some well-known examples of medical encyclopedias include the Merck Manual and the Stedman's Medical Dictionary.

Hyperplasia refers to an increased number of cells, and hypertrophy refers to an increase in the size of individual cells. As ... enlargement Drug induced enlargement Enlargement associated with systemic diseases or conditions Neoplastic enlargement False ... Gingival enlargement has a multitude of causes. The most common is chronic inflammatory gingival enlargement, when the gingivae ... This type of gingival enlargement is sometimes termed "drug induced gingival enlargement" or "drug influenced gingival ...
Giant cell fibroma • Gigantiform cementoma • Gingiva • Gingival and periodontal pockets • Gingival cyst of the adult • Gingival ... cyst of the newborn • Gingival enlargement • Gingival fibers • Gingival sulcus • Gingivectomy • Gingivitis • Giovanni Battista ... Dental pulp stem cells • Dental radiography • Dental restoration • Dental restorative materials • Dental sealant • Dental spa ... Acinic cell carcinoma • Acrodont • Adalbert J. Volck • Adenomatoid odontogenic tumor • Adhesive Dentistry • Aetna • Agar • ...
Characteristics of the tumor cell, and; Virological characteristics The demonstration of peripheral nerve enlargement along ... primitive reticular cells, and occasional plasma cells, as well as macrophage and plasma cells. The T cells are involved in the ... Furthermore, without stimulation by cell-mediated immunity, the humoral immunity conferred by the B-cell lines from the Bursa ... Pleomorphic lymphoid cells in nerves and tumors; and T-cell lymphomas. In addition to gross pathology and histology, other ...
There is a rapid thyroid enlargement. Compression of trachea, dysphagia are probable outcomes. Marked thyroid follicular cell ... The hallmarks of the disease are fibrosis and infiltration by IgG4 secreting plasma cells. IgG4-related autoimmune diseases are ...
Liver cell death and severe lactic acidosis may be present as well. Caudate lobe enlargement is often present. The majority of ... liver enlargement, enlargement of the spleen, fluid accumulation within the peritoneal cavity, elevated liver enzymes, and ... and liver enlargement. It is usually seen in younger adults, with the median age at diagnosis between the ages of 35 and 40, ...
Development proceeds by cell division until maturity; further growth occurs via cell enlargement only. This growth is known as ... In all organisms displaying cell constancy, nuclei division by mitosis in mature cells is not achieved. Embryonic cells are ... The cells from gastric glands and the vitellarium of Hydatina were examined, counted, and statistically analyzed. These cells ... A relationship between mean cell number and cell number variation was established following a law possessing an exponent of 2 ...
This is caused by bilirubin (one of the end products of red blood cell destruction). Enlargement of the newborn's liver and ... Red blood cells lacking Rh/RhAG proteins have structural abnormalities (such as stomatocytosis) and cell membrane defects that ... All Rh antibodies except D display dosage (antibody reacts more strongly with red cells homozygous for an antigen than cells ... or breaking down of red blood cells Erythroblastosis refers to the making of immature red blood cells Fetalis refers to the ...
... the cells that defend the body from foreign invaders) count. Neutropaenia a reduced neutrophil (the white blood cells that kill ... Breast enlargement (in either sex). This is a complication of hyperprolactinaemia. Galactorrhoea (expulsion of milk from the ... which allows cells to utilise sugars for energy. This in turn forces the body to burn fats for energy and fats require ... a part of blood cells that is used to carry oxygen. In most people this is an indication of impaired liver function) Abdominal ...
In the testes, testosterone is produced by the Leydig cells. The male generative glands also contain Sertoli cells, which ... Enlargement of sebaceous glands. This might cause acne, subcutaneous fat in face decreases. Pubic hair extends to thighs and up ... testosterone is synthesized primarily in Leydig cells. The number of Leydig cells in turn is regulated by luteinizing hormone ( ... Cell Biol. 42 (6): 813-27. doi:10.1016/j.biocel.2009.11.013. PMID 19931639. Wang C, Liu Y, Cao JM (2014). "G protein-coupled ...
... the lymphocytes inside of the node trigger a response which can cause proliferation or cell enlargement. This is also referred ... It is known, however, that a stimulation of the B cell compartment and by abnormal cell growth of secondary follicles are key ... It is caused by a stimulation of the B cell compartment and by abnormal cell growth of secondary follicles. This typically ... white and platelet cells found in the blood. If the patient has low blood cell counts, this can be an indication of lymphoma. ...
Splenomegaly can make anemia worse, and it can reduce the life of transfused red blood cells. Severe enlargement of the spleen ... Thalassemia is often accompanied by the destruction of a large number of red blood cells and the task of removing these cells ... 2011). "T cell-depleted hla-haploidentical stem cell transplantation in thalassemia young patients". Pediatric Reports. 3 ( ... Gaziev, J; Lucarelli, G (June 2011). "Hematopoietic stem cell transplantation for thalassemia". Current Stem Cell Research & ...
These enlargements appear to begin as early as their last instar as larvae. The lateral oviducts of healthy, adult female moths ... areone or two cell layers; those of infected female moths have four to eight layers instead. These enlargements may increase ... Both viruses can replicate in cell cultures, though only HzNV-2 can replicate in an insect host. The genomes of HzNV-2 and HzNV ... Hink WF, Ignoffo CM (May 1970). "Establishment of a new cell line (IMC-HZ-1) from ovaries of cotton bollworm moths, Heliothis ...
Glomerular enlargement may be observed. Ultrastructural changes evaluated with electron microscopy were mostly consistent with ... Large dysmorphic lysosomes within tubular epithelial cells have been proposed as a distinctive feature but at present are not ...
Sorrosa, J. M.; M. Satoh; Y. Shiraiwa (2005). "Low temperature stimulates cell enlargement and intracellular calcification of ... Prymnesiophyceae)". Plant and Cell Physiology. 40 (7): 762-766. doi:10.1093/oxfordjournals.pcp.a029603. DeBose, J. L.; S. C. ... During massive blooms (which can cover over 100,000 square kilometers), E. huxleyi cell concentrations can outnumber those of ... Plant Cell Physiology. 45 (10): 1434-1441. doi:10.1093/pcp/pch164. PMID 15564527. Read, B.; J. Kegel; MJ. Klute (2013). "Pan ...
T cells against infected B lymphocytes, resulting in enlarged, atypical lymphocytes (Downey cells). When the infection is acute ... Spleen enlargement is common in the second and third weeks, although this may not be apparent on physical examination. Rarely ... They are more likely to have liver enlargement and jaundice. People over 40 years of age are more likely to develop serious ... There may also be some enlargement of the liver. Jaundice occurs only occasionally. It generally gets better on its own in ...
Meanwhile, enlargement of heart cells will reduce the T1 signal. Using T1 signal, Extracellular volume (ECV) is useful to ... One of the major routes to decrease the production of these excess light chains is to kill the abnormal cells that are ... Chemotherapeutic agents such as melphalan or bortezomib can be used to kill off the abnormal cell line that is producing the ... These chains are created by an abnormal expansion of plasma cells. Over time, these light chains deposit into the interstitial ...
Enlargement of the liver and spleen, or hepatosplenomegaly is characteristic. The mast cells release also many anticoagulants ... If the mast cells represent less than 10% of blood cells, the tumor is called "aleukemic" mast cell leukemia. Acute mast cell ... Mast cell tryptase is an enzyme contained in mast cell granules. Mast cell numbers are best estimated by tryptase ... The cells usually express CD2 and CD25. Malignant mast cells overexpress the anti-apoptosis gene, bcl-2. A mutation called KIT ...
Image shows open-cell brain terrain and closed-cell brain terrain, which is more common. Open-cell brain terrain is thought to ... Note: this is an enlargement of the previous CTX image. Lineated valley fill, as seen by HiRISE under HiWish program. Close ... Closed-cell brain terrain, as seen by HiRISE under the HiWish program. This type of surface is common on lobate debris aprons, ... Open- and closed-cell brain terrain, as seen by HiRISE, under HiWish program. Wide CTX view showing mesa and buttes with lobate ...
... lymph node enlargement (90%) including those in the mediastinum (36%); and lymphomatous lesions in the skin (26%), bone (14%), ... pcALCL lesions exhibit large malignant T-cells or null cells (i.e. cells lacking many T-cell receptor proteins) with "Hallmark ... a small-cell pattern consisting of small to medium-sized neoplastic cells with clear cytoplasm and "hallmark" cells that are ... These cells do not express ALK and often lack the characteristic surface marker proteins of T-cells. Identification of the ...
... the degree of host nucleus displacement and the degree of host cell enlargement. DNA studies should help to clarify this area ... straight gametocytes that normally occur in anucleate cells and are almost as long as the host cell (H. enucleator) Gametocytes ... Once the vector bites a new host, the sporozoites enter the blood stream and invade endothelial cells of blood vessels within ... Within the endothelial cells, the sporozoites undergo asexual reproduction becoming schizonts. These in turn produce numerous ...
Ultrasound or computerized tomography may show hydrops (enlargement) of the gallbladder. Urinalysis may show white blood cells ... Systemic vasculitides may be classified according to the type of cells involved in the proliferation, as well as the specific ... Due to the potential involvement of the upregulated calcium-nuclear factor of activated T cells pathway in the development of ... high white-blood-cell count, high band count, high CRP concentrations, male sex, and age less than one year. Coronary artery ...
Waste rock removal: Rock extracted from the mine was removed from tailings piles and disposed of in a compacted cell. In ... This plan was implemented, removing the need for the dam enlargement. ...
Their most significant enlargements takes place during puberty.: 746 The air cells are hypothesised to protect the temporal ... The mastoid cells (also called air cells of Lenoir or mastoid cells of Lenoir) are air-filled cavities within the mastoid ... The term "cells" here refers to enclosed spaces, not cells as living, biological units. The mastoid air cells vary greatly in ... The mastoid cells are a form of skeletal pneumaticity. Infection in these cells is called mastoiditis. ...
... and vacuolation of cells undergoing paraptosis can be seen through light microscopy. There is physical enlargement of the ... In the NB4 cell line, paraptosis was the primary method of cell death. In K562 cells, apoptosis was the primary mechanism, with ... Cell death induced by IGFIR-IC in 293T cells demonstrated cell death without associated caspase activity. This is in comparison ... to stimulate cell death in 293T cells and mouse embryonic fibroblasts, observing distinct differences from other forms of cell ...
... leading to cell enlargement. This enlargement is made possible by the sliding of polymers, increasing the cell wall's surface ... Treating living cells with acid induces acidification of the cell wall by activating an ATPase in the cell wall's plasma ... The stretching of the cell wall, or the reduction of stress, occurs as a result of cell expansion and rearrangement. Cell ... as it opposes the pressure of the cell's primary cell wall; this also allows for stretching of the cell wall. ...
Studies show elevated levels of leukocytes, or white blood cells, which is referred to as eosinophilia. It is mainly found in ... In addition, it causes spleen and liver enlargement, which is called hepatosplenomegaly. ... If there are abnormally high levels of white blood cells, then a physical examination will most likely find an enlarged spleen ... Relative eosinophilia is different from absolute because relative refers to an increase in percentage of white blood cells (i.e ...
Vegetative cells are capable of enlargement and may also produce resting spores. However, samples from Puget Sound, WA display ... The D. brightwellii cell has a high length to diameter ratio. The cell wall is silicified, as is characteristic of all diatoms ... Oceanic currents and surface winds prevent D. brightwellii cells from sinking beneath the euphotic zone. Cells range in size ... This hard, porous covering is known as the frustule and causes the cell to be more dense than the surrounding water. ...
... cells may also colonize diatoms during instances of vegetative cell enlargement. Cyanobacteria in the genus Richelia ... Richelia's trichomes are made up of two cell types: Heterocyst and Vegetative. The heterocyst is a terminal single cell within ... Within diatoms that are dead or dying, some Richelia cells have enlarged and rounded vegetative cells, some begin to ... Also hypothesized is that Richelia cells may be affiliated with auxospore cells, or may enter diatoms during sexual ...
... medium-sized cells with prominent nucleoli (15-18 µm) and, large cells (50-100 µm). The cells are generally packed into nodules ... Most present with slow, painless testicular enlargement, which may involve both testes. Spermatocytic tumors are diagnosed ... Cells undergoing mitosis are common, as are cells undergoing apoptosis. Intratubular growth of spermatocytic tumor can be seen ... Histologically, spermatocytic tumors consist of three cell populations: small cells with a large nuclear-to-cytoplasmic ratio ( ...
It works in two ways, first by disrupting cell membranes and mitochondria resulting cell death, and then by inducing antibody- ... rapid enlargement), B (bleeding), E (erythema), and U (ulceration). AKs are usually diagnosed clinically, but because they are ... Clinical practice guide: basal cell carcinoma, squamous cell carcinoma (and related lesions): a guide to clinical management in ... These cells have been observed to proliferate into the dermis as buds and duct-like structures. Lichenoid: Demonstrate a band- ...
Ovocytes appear to be among the infected cells and their nuclei are hypertrophic, and the host does not noticeably respond with ... A hypertrophy has also been observed in spermatocytes; in general an enlargement of the gametes is observed. Such viruses have ...
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  • The acute syndrome presents with rapidly progressive severe upper abdominal pain , yellow discoloration of the skin and whites of the eyes , liver enlargement , enlargement of the spleen , fluid accumulation within the peritoneal cavity , elevated liver enzymes , and eventually encephalopathy . (wikipedia.org)
  • and enlargement of the spleen (splenomegaly). (medlineplus.gov)
  • It causes a sudden, painful enlargement of the spleen. (healthline.com)
  • The spleen may have to be removed due to complications of sickle cell disease in an operation known as a splenectomy. (healthline.com)
  • Some sickle cell patients will sustain enough damage to their spleen that it becomes shrunken and ceases to function at all. (healthline.com)
  • The cutaneous form presents with skin ulcers, while the mucocutaneous form presents with ulcers of the skin, mouth and nose and the visceral form starts with skin ulcers and then later presents with fever, low red blood cells, and a large spleen and liver. (disabled-world.com)
  • In extremely rare cases, affected individuals may experience abnormal enlargement of the liver and/or spleen (hepatosplenomegaly). (rarediseases.org)
  • Niemann-Pick disease is a group of autosomal recessive disorders caused by an accumulation of fat and cholesterol in cells of the liver, spleen, bone marrow, lungs, and, in some instances, brain. (nih.gov)
  • Enlargement of the liver and spleen characteristically occurs in the early adolescence. (nih.gov)
  • These were attributed to a genetic disorder, an enlargement of the liver and spleen. (cdc.gov)
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  • A cavitating right lower lobe squamous cell carcinoma. (medscape.com)
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  • On histopathology, the tumours consist of mixed populations of neoplastic lymphoid cells and inflammatory cells that include lymphocytes (primarily T cells) and macrophages ( Fig. 1D ). (uoguelph.ca)
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  • While normal thyrocytes were detected in thyroid gland, atypical lymphoid cells showing diffuse infiltration in thyroid tissue were observed in the nodule, which were stained diffuse, strongly positive for CD20 and BcL and negative for CD45 RO. (endocrine-abstracts.org)
  • According to Revised European American Classification of Lymphoid Neoplasms, the diagnosis was diffuse large B-cell lymphoma. (endocrine-abstracts.org)
  • We introduce the case in order to emphasize that infiltration of diffuse large B-cell lymphoma should be recalled with instantaneous enlargement of nodules known to be benign previously, and when cytological specimen is uncertain, immunohistochemical staining should be performed for differential diagnosis. (endocrine-abstracts.org)
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  • The symptoms are non-specific and vary widely, but it may present with the classical triad of abdominal pain, ascites , and liver enlargement . (wikipedia.org)
  • Liver cell death and severe lactic acidosis may be present as well. (wikipedia.org)
  • Additionally, moderate proliferation of the fibrous connective tissue and the myoepithelial cells near the proliferating acini was evident. (scielo.br)
  • Rosai-Dorfman disease is a rare disorder characterized by overproduction (proliferation) and accumulation of a specific type of white blood cell (histiocyte) in the lymph nodes of the body (lymphadenopathy), most often those of the neck (cervical lymphadenopathy). (rarediseases.org)
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  • Gingival enlargement has been classified according to cause into 5 general groups: Inflammatory enlargement Drug induced enlargement Enlargement associated with systemic diseases or conditions Neoplastic enlargement False enlargement. (wikipedia.org)
  • Fine needle aspiration was performed and revealed inflammatory cells with degenerative changes but neoplastic malformation could not be ruled out. (who.int)
  • If you have only one copy of the gene, you are said to have sickle cell trait. (healthline.com)
  • People who only inherit a mutated gene (hemoglobin S) from one parent are said to have sickle cell trait. (healthline.com)
  • Children are only at risk for sickle cell disease if both parents carry sickle cell trait. (healthline.com)
  • This distribution reflects the fact that sickle-cell trait confers a survival advantage against malaria and that selection pressure due to malaria has resulted in high frequencies of the mutant gene especially in areas of high malarial transmission. (who.int)
  • The sickle-cell gene has become common in Africa because the sickle-cell trait confers some resistance to falciparum malaria during a critical period of early childhood, favouring survival of the host and subsequent transmission of the abnormal haemoglobin gene. (who.int)
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  • In the lymph node, diffusely infiltrating atypical lymphoid cells with similar immunohistochemical staining properties were observed. (endocrine-abstracts.org)
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  • These are not precise descriptions of gingival enlargement because these terms are strictly histologic diagnoses, and such diagnoses require microscopic analysis of a tissue sample. (wikipedia.org)
  • As these identifications cannot be performed with a clinical examination and evaluation of the tissue, the term gingival enlargement is more properly applied. (wikipedia.org)
  • Some investigators assert that underlying inflammation is necessary for the development of drug-induced enlargement, while others purport that the existing enlargement induced by the drug effect compounds plaque retention, thus furthering the tissue response. (wikipedia.org)
  • Situations in which the chronic inflammatory gingival enlargement include significant fibrotic components that do not respond to and undergo shrinkage when exposed to scaling and root planing are treated with surgical removal of the excess tissue, most often with a procedure known as gingivectomy. (wikipedia.org)
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  • Sickle beta-zero thalassemia is the fourth type of sickle cell disease. (healthline.com)
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