Connections between cells which allow passage of small molecules and electric current. Gap junctions were first described anatomically as regions of close apposition between cells with a narrow (1-2 nm) gap between cell membranes. The variety in the properties of gap junctions is reflected in the number of CONNEXINS, the family of proteins which form the junctions.
Direct contact of a cell with a neighboring cell. Most such junctions are too small to be resolved by light microscopy, but they can be visualized by conventional or freeze-fracture electron microscopy, both of which show that the interacting CELL MEMBRANE and often the underlying CYTOPLASM and the intervening EXTRACELLULAR SPACE are highly specialized in these regions. (From Alberts et al., Molecular Biology of the Cell, 2d ed, p792)
Oligonucleotide Array Sequence Analysis
Gene Expression Profiling
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
Gene Expression Regulation
Communication Aids for Disabled
Equipment that provides mentally or physically disabled persons with a means of communication. The aids include display boards, typewriters, cathode ray tubes, computers, and speech synthesizers. The output of such aids includes written words, artificial speech, language signs, Morse code, and pictures.
Computer Communication Networks
Radiology Information Systems
Communication, in the sense of cross-fertilization of ideas, involving two or more academic disciplines (such as the disciplines that comprise the cross-disciplinary field of bioethics, including the health and biological sciences, the humanities, and the social sciences and law). Also includes problems in communication stemming from differences in patterns of language usage in different academic or medical disciplines.
The homeobox gene Pitx2: mediator of asymmetric left-right signaling in vertebrate heart and gut looping. (1/8670)Left-right asymmetry in vertebrates is controlled by activities emanating from the left lateral plate. How these signals get transmitted to the forming organs is not known. A candidate mediator in mouse, frog and zebrafish embryos is the homeobox gene Pitx2. It is asymmetrically expressed in the left lateral plate mesoderm, tubular heart and early gut tube. Localized Pitx2 expression continues when these organs undergo asymmetric looping morphogenesis. Ectopic expression of Xnr1 in the right lateral plate induces Pitx2 transcription in Xenopus. Misexpression of Pitx2 affects situs and morphology of organs. These experiments suggest a role for Pitx2 in promoting looping of the linear heart and gut. (+info)
oko meduzy mutations affect neuronal patterning in the zebrafish retina and reveal cell-cell interactions of the retinal neuroepithelial sheet. (2/8670)Mutations of the oko meduzy (ome) locus cause drastic neuronal patterning defect in the zebrafish retina. The precise, stratified appearance of the wild-type retina is absent in the mutants. Despite the lack of lamination, at least seven retinal cell types differentiate in oko meduzy. The ome phenotype is already expressed in the retinal neuroepithelium affecting morphology of the neuroepithelial cells. Our experiments indicate that previously unknown cell-cell interactions are involved in development of the retinal neuroepithelial sheet. In genetically mosaic animals, cell-cell interactions are sufficient to rescue the phenotype of oko meduzy retinal neuroepithelial cells. These cell-cell interactions may play a critical role in the patterning events that lead to differentiation of distinct neuronal laminae in the vertebrate retina. (+info)
The Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinase. (3/8670)Stimulation of the hepatocyte growth factor (HGF) receptor tyrosine kinase, Met, induces mitogenesis, motility, invasion, and branching tubulogenesis of epithelial and endothelial cell lines in culture. We have previously shown that Gab1 is the major phosphorylated protein following stimulation of the Met receptor in epithelial cells that undergo a morphogenic program in response to HGF. Gab1 is a member of the family of IRS-1-like multisubstrate docking proteins and, like IRS-1, contains an amino-terminal pleckstrin homology domain, in addition to multiple tyrosine residues that are potential binding sites for proteins that contain SH2 or PTB domains. Following stimulation of epithelial cells with HGF, Gab1 associates with phosphatidylinositol 3-kinase and the tyrosine phosphatase SHP2. Met receptor mutants that are impaired in their association with Gab1 fail to induce branching tubulogenesis. Overexpression of Gab1 rescues the Met-dependent tubulogenic response in these cell lines. The ability of Gab1 to promote tubulogenesis is dependent on its pleckstrin homology domain. Whereas the wild-type Gab1 protein is localized to areas of cell-cell contact, a Gab1 protein lacking the pleckstrin homology domain is localized predominantly in the cytoplasm. Localization of Gab1 to areas of cell-cell contact is inhibited by LY294002, demonstrating that phosphatidylinositol 3-kinase activity is required. These data show that Gab1 is an important mediator of branching tubulogenesis downstream from the Met receptor and identify phosphatidylinositol 3-kinase and the Gab1 pleckstrin homology domain as crucial for subcellular localization of Gab1 and biological responses. (+info)
p27 is involved in N-cadherin-mediated contact inhibition of cell growth and S-phase entry. (4/8670)In this study the direct involvement of cadherins in adhesion-mediated growth inhibition was investigated. It is shown here that overexpression of N-cadherin in CHO cells significantly suppresses their growth rate. Interaction of these cells and two additional fibroblastic lines with synthetic beads coated with N-cadherin ligands (recombinant N-cadherin ectodomain or specific antibodies) leads to growth arrest at the G1 phase of the cell cycle. The cadherin-reactive beads inhibit the entry into S phase and the reduction in the levels of cyclin-dependent kinase (cdk) inhibitors p21 and p27, following serum-stimulation of starved cells. In exponentially growing cells these beads induce G1 arrest accompanied by elevation in p27 only. We propose that cadherin-mediated signaling is involved in contact inhibition of growth by inducing cell cycle arrest at the G1 phase and elevation of p27 levels. (+info)
Endothelial cells modulate the proliferation of mural cell precursors via platelet-derived growth factor-BB and heterotypic cell contact. (5/8670)Embryological data suggest that endothelial cells (ECs) direct the recruitment and differentiation of mural cell precursors. We have developed in vitro coculture systems to model some of these events and have shown that ECs direct the migration of undifferentiated mesenchymal cells (10T1/2 cells) and induce their differentiation toward a smooth muscle cell/pericyte lineage. The present study was undertaken to investigate cell proliferation in these cocultures. ECs and 10T1/2 cells were cocultured in an underagarose assay in the absence of contact. There was a 2-fold increase in bromodeoxyuridine labeling of 10T1/2 cells in response to ECs, which was completely inhibited by the inclusion of neutralizing antiserum against platelet-derived growth factor (PDGF)-B. Antisera against PDGF-A, basic fibroblast growth factor, or transforming growth factor (TGF)-beta had no effect on EC-stimulated 10T1/2 cell proliferation. EC proliferation was not influenced by coculture with 10T1/2 cells in the absence of contact. The cells were then cocultured so that contact was permitted. Double labeling and fluorescence-activated cell sorter analysis revealed that ECs and 10T1/2 cells were growth-inhibited by 43% and 47%, respectively. Conditioned media from contacting EC-10T1/2 cell cocultures inhibited the growth of both cell types by 61% and 48%, respectively. Although we have previously shown a role for TGF-beta in coculture-induced mural cell differentiation, growth inhibition resulting from contacting cocultures or conditioned media was not suppressed by the presence of neutralizing antiserum against TGF-beta. Furthermore, the decreased proliferation of 10T1/2 cells in the direct cocultures could not be attributed to downregulation of the PDGF-B in ECs or the PDGF receptor-beta in the 10T1/2 cells. Our data suggest that modulation of proliferation occurs during EC recruitment of mesenchymal cells and that heterotypic cell-cell contact and soluble factors play a role in growth control during vessel assembly. (+info)
Cell surface sialic acid and the regulation of immune cell interactions: the neuraminidase effect reconsidered. (6/8670)It has been known for over a decade that sialidase (neuraminidase) treatment could substantially enhance the capacity of resting B cells to stimulate the proliferation of allogeneic and antigen specific, syngeneic T cells. Thus, cell-surface sialic acid was implicated as a potential modulator of immune cell interaction. However, little progress has been made in either identifying explicit roles for sialic acid in this system or in hypothesizing mechanisms to explain the "neuraminidase effect." Here we show for the first time that cell surface sialic acid on medium incubated B cells blocks access to costimulatory molecules on the B cell surface, and that this is the most likely explanation for the neuraminidase effect. Further, we show that it is likely to be upregulation of ICAM-1 and its subsequent engagement of LFA-1 rather than loss of cell surface sialic acid that in part regulates access to CD86 and other costimulatory molecules. However, we cannot exclude a role for CD86-bound sialic acid on the B cell in modulating binding to T cell CD28. Because sialidase treatment of resting B cells but not resting T cells enables T cell activation, we suggest that sialidase treatment may still be an analogue for an authentic step in B cell activation, and show that for highly activated B cells (activated with polyclonal anti-IgM plus INF-gamma) there is specific loss 2, 6-linked sialic acid. Potential roles for sialic acid in modulating B cell/T cell collaboration are discussed. (+info)
Glucocorticoid down-regulation of fascin protein expression is required for the steroid-induced formation of tight junctions and cell-cell interactions in rat mammary epithelial tumor cells. (7/8670)Glucocorticoid hormones, which are physiological regulators of mammary epithelium development, induce the formation of tight junctions in rat Con8 mammary epithelial tumor cells. We have discovered that, as part of this process, the synthetic glucocorticoid dexamethasone strongly and reversibly down-regulated the expression of fascin, an actin-bundling protein that also interacts with the adherens junction component beta-catenin. Ectopic constitutive expression of full-length mouse fascin containing a Myc epitope tag (Myc-fascin) in Con8 cells inhibited the dexamethasone stimulation of transepithelial electrical resistance, disrupted the induced localization of the tight junction protein occludin and the adherens junction protein beta-catenin to the cell periphery, and prevented the rearrangement of the actin cytoskeleton. Ectopic expression of either the carboxyl-terminal 213 amino acids of fascin, which includes the actin and beta-catenin-binding sites, or the amino-terminal 313 amino acids of fascin failed to disrupt the glucocorticoid induction of tight junction formation. Mammary tumor cells expressing the full-length Myc-fascin remained generally glucocorticoid responsive and displayed no changes in the levels or protein-protein interactions of junctional proteins or the amount of cytoskeletal associated actin filaments. However, a cell aggregation assay demonstrated that the expression of Myc-fascin abrogated the dexamethasone induction of cell-cell adhesion. Our results implicate the down-regulation of fascin as a key intermediate step that directly links glucocorticoid receptor signaling to the coordinate control of junctional complex formation and cell-cell interactions in mammary tumor epithelial cells. (+info)
Novel insights into human endometrial paracrinology and embryo-maternal communication by intrauterine microdialysis. (8/8670)The regulation of human implantation is still unknown. Evidence from mice suggests an essential role for several paracrine mediators but species differences with implantation in the human preclude the extrapolation of these concepts to humans. An intrauterine microdialysis device (IUMD), consisting of microdialysis tubing glued into a balloon catheter on one side and into a polypropylene tube on the other, allows a dynamic and accurate in-vivo measurement of uterine paracrine interactions in humans. Inserted into the uterine cavity in the form of a loop, it can be continuously perfused with saline to reveal a number of relevant cytokines and growth factors in uterine effluents of non-pregnant women in both follicular and luteal phases. These included interleukin (IL)-1alpha, IL-1beta, IL-6, leukaemia inhibitory factor (LIF), macrophage colony-stimulating factor (M-CSF), epidermal growth factor, vascular endothelial growth factor (VEGF), insulin-like growth factor binding protein-1 (IGFBP-1), prolactin, and human chorionic gonadotrophin (HCG). The source of intrauterine HCG is unclear since endometrial mRNA for the HCG beta-subunit is not revealed using reverse transcriptase polymerase chain reaction analysis. Applying urinary HCG locally via the IUMD profoundly alters endometrial secretory parameters. Prolactin, IGFBP-1, and M-CSF are significantly inhibited and VEGF is regulated in a biphasic manner involving early stimulation followed by inhibition of intrauterine levels. Use of the IUMD has thus shown that the urinary HCG preparations routinely used for ovulation induction and luteal support may directly alter endometrial function. (+info)
Patent US5940753 - Controller for cellular communications system - Google Patents
A cellular communications system is provided have both satellite nodes and surface nodes for providing mobile cellular communications services for a plurality of mobile user units. The surface and satellite nodes are fully integrated by a network controller for providing service over large areas. Multiple beam, relatively high gain antennas are disposed in the satellite nodes to establish satellite cells having enough gain in the satellite part of the system such that a user unit need only comprise a small, mobile handset with a non-directional antenna for communications with both ground nodes and satellite nodes.
The Rhomboid family of intramembrane proteases, conserved regulators of cell communication
The development of multicellular organisms relies heavily on cell communication. Cells send and receive complex sets of signals, harmonising their growth and differentiation with that of other, often distant, cell populations. In animals, the Epidermal Growth Factor Receptor (EGFR) is an important mediator of cell communication. EGFR activation regulates various developmental events in nematodes, insects and vertebrates. In addition, mutations in human EGFRs have been associated with a number of cancers. In Drosophila, a key event triggering EGFR signalling is the regulated release of the extracellular portion of EGFR ligands. Rhomboid (Rho), an unusual polytopic protease, cleaves the transmembrane, inactive ligand precursor into an active, soluble form. Both the target sequence and Rho s catalytic site are embedded within the membrane bilayer and for this reason the reaction has been described as regulated intramembrane proteolysis. The work presented in this thesis begins with the ...
Ai/E10 (30 count) - Immune Cell Communication - Vita Day Products
ITEM 01003721 AiE10 Helps To Support Immune Cell Communication Ai/E10 supports healthy immune cell communication by providing a concentrate of immune system messengers. BENEFITS OF AiE10 Provides additional low molecular weight molecules including cytokines, lactoferrin, lysozymes, defensins, and disaccharides* Provid
ENGR213 lecture3 - Cell Signaling and Cellular Communication Lecture 3 What is Cell Signaling Cell signaling is part of a...
View Notes - ENGR213_lecture3 from ENGR 213 at Cal Poly. Cell Signaling and Cellular Communication Lecture 3 What is Cell Signaling ? Cell signaling is part of a complex system of communication
Chapter 11 - Chapter 11 Cell Communication Overview The Cellular Internet Cell-to-cell communication is essential for...
View Notes - Chapter 11 from BIOL 211 at Bellevue College. Chapter 11 Cell Communication Overview: The Cellular Internet Cell-to-cell communication is essential for multicellular organisms Biologists
Overview On 5G-Massive MIMO Cellular Communication<...
TY - GEN. T1 - Overview On 5G-Massive MIMO Cellular Communication. AU - Kamath, H. Srikanth. AU - Adarsh, PY - 2019/8. Y1 - 2019/8. N2 - Massive MIMO is most fundamental and the basis of 5G. Whole evolution from older generation to 5G in context of data speed, huge amount of data traffic handling capacity, decrease in response time, providing very large range of bandwidth, increase in coverage are, high energy efficiency and many others has been done due to this new technology called Massive MIMO. It is the basic building block for 5G, whole 5G is built upon Massive MIMO. Objectives: This paper presents the basic working of 5G networks in terms of Massive MIMO and tries to find answer of question like how it increases the capacity of data handling by a huge amount as much as 1000 times more, how it gives such high speeds, what are the concept behind this significant improvements, will there be significant increase in size of BS since massive number of antennas are used. There is also a ...
Shungite Effect of radiation from cellular communications equipment on vital bodily functions when shielded with shungite
Effect of radiation from cellular communications equipment on vital bodily fUnctions when shielded with shungite S. P. KUROTCHENKO*, T. I. SUBB...
Cellular Communication Routers Market to Witness an Outstanding Growth During 2021- 2026
The Cellular Communication Routers market report offers a granular evaluation of this industry landscape. According to the document, the market is estimated to generate substantial revenues as well as register a robust growth rate during the projected timeframe.
describes what glyconutritionals are and how they are used to increase cellular communication, which in turn provides optimal health.
New windows opened on cell-to-cell interactions (w/ Video)
Applying biological molecules from cell membranes to the surfaces of artificial materials is opening peepholes on the very basics of cell-to-cell interaction.
Biology, The Cell, Cell Communication, Signaling in Single-Celled Organisms | OER Commons
Cellular Communication in YeastsThe first life on our planet consisted of single-celled prokaryotic organisms that had limited interaction with each other. While some external signaling occurs between different species of single-celled organisms, the majority of signaling within bacteria and yeasts concerns only other members of the same species. The evolution of cellular communication is an absolute necessity for the development of multicellular organisms, and this innovation is thought to have required approximately 2.5 billion years to appear in early life forms.. Yeasts are single-celled eukaryotes, and therefore have a nucleus and organelles characteristic of more complex life forms. Comparisons of the genomes of yeasts, nematode worms, fruit flies, and humans illustrate the evolution of increasingly complex signaling systems that allow for the efficient inner workings that keep humans and other complex life forms functioning correctly.. Kinases are a major component of cellular ...
Analysis of HIV-1 cell-to-cell transfer to macrophages / Lucie Bracq ; sous la direction de Serge Bénichou et de Paul Zhou -...
Sudoc Catalogue :: - Livre / BookAnalysis of HIV-1 cell-to-cell transfer to macrophages / Lucie Bracq ; sous la direction de Serge Bénichou et de Paul Zhou
Bidirectional Interactions between Antigen-bearing Respiratory Tract Dendritic Cells (DCs) and T Cells Precede the Late Phase...
Bidirectional Interactions between Antigen-bearing Respiratory Tract Dendritic Cells (DCs) and T Cells Precede the Late Phase Reaction in Experimental Asthma: DC Activation Occurs in the Airway Mucosa but Not in the Lung ...
Mechanism-based model characterizing bidirectional interaction between | IJN
Mechanism-based model characterizing bidirectional interaction between PEGylated liposomal CKD-602 (S-CKD602) and monocytes in cancer patients Huali Wu,1 Ramesh K Ramanathan,2 Beth A Zamboni,3 Sandra Strychor,4 Suresh Ramalingam,5 Robert P Edwards,4 David M Friedland,4 Ronald G Stoller,4 Chandra P Belani,4 Lauren J Maruca,4 Yung-Jue Bang,6 William C Zamboni11UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, USA; 2Translational Research Division, The Translational Genomics Research Institute, Scottsdale, AZ, USA; 3Department of Mathematics, Carlow University, Pittsburgh, PA, USA; 4School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA; 5Winship Cancer Institute, Emory University, Atlanta, GA, USA; 6College of Medicine, Seoul National University, Seoul, KoreaAbstract: S-CKD602 is a PEGylated liposomal formulation of CKD-602, a potent topoisomerase I inhibitor. The objective of this study was to characterize the bidirectional pharmacokinetic-pharmacodynamic (PK-PD)
Biology Chapter 11 Cell Communication Flashcards - Cram.com
Study Flashcards On Biology Chapter 11 Cell Communication at Cram.com. Quickly memorize the terms, phrases and much more. Cram.com makes it easy to get the grade you want!
Gap Junctions: Molecular Basis of Cell Communication in Health and Disease, Volume 49 - 1st Edition
Purchase Gap Junctions: Molecular Basis of Cell Communication in Health and Disease, Volume 49 - 1st Edition. Print Book & E-Book. ISBN 9780125506458, 9780080925240
Cellular mechanisms of regulation of the inflammatory response in atherosclerosis: the role of cell contact-mediated signaling]...
The regulatory mechanisms of the inflammatory process in the atherosclerotic plaque are still not clearly understood. Stimulated T cells may have a key role in enhancing and perpetuating inflammation at the atherosclerotic site. They activate endothelial cells, macrophages and smooth muscle cells in the atherosclerotic plaque, not only via the production of soluble mediators, but also through cell-cell contact-mediated interactions (via membrane receptors and their ligands). Cell/cell contact between stimulated T lymphocytes and monocytes/macrophages and endothelial cells induces the production of pro-inflammatory cytokines (tumor necrosis factor-alpha, interleukin-6) and chemokines (interleukin-8, monocyte chemotactic factor-1). Thus, these interactions could play a relevant role in the disregulation of the inflammatory process in the atherosclerotic plaque, representing a novel mechanism of progression and complication of the atherosclerotic disease. Understanding the key ligands and receptors
Nerve cell communication mechanisms uncovered, may lead to new therapeutic approaches for neurodegenerative diseases
How it works: Rebuilding cell theory. Garcias early research disproved a long-standing hypothesis concerning this cellular feature.. Mammals nervous systems are uniquely equipped with myelination, which has been shown to increase conduction velocity, or the speed at which nerve cells pass signals. Low velocity is often associated with neurodegenerative diseases, so research exploring why could later have application in therapeutic technology.. In addition to myelination, cell size makes a big difference in conduction velocity - the bigger the nerve cells, the faster they can pass and receive signals. Garcias findings disproved a hypothesis that related myelination to this phenomenon.. The hypothesis, published in a 1992 edition of Cell, claimed that myelination causes a cellular process called phosphorylation which then causes an increase in the axonal diameter (width of the communicating part of a nerve cell), leading to faster nerve cell communication. Garcia found that myelination did ...
Phone Mobile Cell Communication Wireless Images | Free Clip Art & Vector Art At Clker
Search and use 100s of phone mobile cell communication wireless clip arts and images all free! Royalty free, no fees, and download now in the size you need.
Cell Communication and Signaling | Articles
Welcoming basic and translational aspects of cell communication and signaling research that influence cellular morphology, structure, and function in both ...
Cell Communication and Signaling | Articles
Welcoming basic and translational aspects of cell communication and signaling research that influence cellular morphology, structure, and function in both ...
Citation Machine: Cell Communication And Signaling format citation generator for raw rata
Citation Machine™ helps students and professionals properly credit the information that they use. Cite your raw rata in Cell Communication and Signaling format for free.
British Library EThOS: Characterisation of HIV-1 Cell-to-Cell Transfer across the Virological Synapse.
HIV-1 is believed to spread by two mechanisms in an infected host: by cell-free virions and by cell-associated transmission. The mechanisms of HIV-1 cell-to-cell transmission were not well understood until the recent description of the virological synapse (VS). The VS is a specialised supramolecular structure, formed between an infected effector cell and a permissive target cell, to facilitate direct virus infection of the permissive cell. Direct cell-to-cell spread is probably an important mechanism in tissues densely populated with target cells, such as CD4+ T cells in lymph nodes and the GALT. Moreover, VS-mediated viral transfer may help the virus to hide from elements of the immune system, such as neutralising antibodies and complement. Many areas relating to HIV-1 cell-to-cell spread and VS function remain to be explored. Therefore, the aim of the project behind this thesis was to extend our initial molecular characterisation of the supramolecular structure of VS in T cells and to ...
Ccn1 cellular communication network factor 1 [Mus musculus (house mouse)] - Gene - NCBI
These reference sequences exist independently of genome builds. Explain. These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above. ...
IUCr) Structural Dynamics in Cellular Communications
Join VIB at its first conference on Structural dynamics in cellular communication that will take place in an architecturally significant venue in the heart of Europe (Brussels, Belgium) from 9-10 February, 2015.. The conference will cover the latest advances in protein science, focusing on systems structural biology, the functional role of structural dynamics, the organization of complexes and key technological advances. During four plenary sessions this first edition will handle the following topics: macromolecular machines and assemblages; protein network dynamics; protein fluctuations and function; and membrane proteins and complexes ...
Researchers demystifying complex cellular communications hubs found in sensory neurons
Its safe to say that cilia, the hairlike appendages jutting out from the smooth surfaces of most mammalian cells, have long been misunderstood - underestimated, even.
Robott - Page 3 - Mobile Technology Is The Technology Used For Cellular Communication
How to Select the Best Throttle Controller Device for Your Car Are you looking for the best throttle controller device for your car?…. Read More ...
Direct cell-cell communications and social behavior of cells in mammals, protists, and bacteria. Possible causes of...
Read Direct cell-cell communications and social behavior of cells in mammals, protists, and bacteria. Possible causes of multicellularity, Russian Journal of Developmental Biology on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
Cell-Cell Interactions - Tom P. Fleming - Oxford University Press
The book comprises ten chapters written by experts in the field on cell-cell interactions and their role in biology and medicine. Cell-cell interactions are the means by which cells are able to communicate, transfer information, develop spatial awareness and coordinate their differentiation. The ten areas have been selected for their breadth and relevance to modern research scientists where cell-cell interactions have been shown to play a critical role in biological processes.
E1A oncogene induction of cellular susceptibility to killing by cytolytic lymphocytes through target cell sensitization to...
E1A oncogene expression increases mammalian cell susceptibility to lysis by cytolytic lymphocytes (CLs) at a stage in this intercellular interaction that is independent of cell surface recognition events. Since CLs can induce either apoptotic or necrotic cell death, we asked whether E1A sensitizatio …
Scientists reveal details of brain cell communication: implications for learnin...( lectrical stimulation and allow calcium...)
lectrical stimulation and allow calcium to flow into dendritic spines.... In their study Sabatini and Svoboda could detect if single calcium... Visually examining calcium fluctuations in a single dendritic spin... But nothing is that simple in the brain. Which type of channel is c... The local influx of calcium we have observed in spines is a fundam...,Scientists,reveal,details,of,brain,cell,communication:,implications,for,learning,&,memory,biological,biology news articles,biology news today,latest biology news,current biology news,biology newsletters
Study brings secrets of brain cell communication closer
Researchers at The University of Queenslands Queensland Brain Institute (QBI) have taken a significant step towards unravelling the mechanism by which communication between brain cells occurs.
Cell communication modelled - Niels Bohr Institute - University of Copenhagen
Animals and plants need to know what is happening throughout their organism. For that an organised communication system is needed, so that the body or the plant knows what is happening all the way out in the...
Cell Communication - Causative Agent - ALPF Medical Research
Surface receptors are integral membrane proteins to which certain signal molecules bind. They generally span the cell membrane, connecting the outside of the cell with the inside, enabling the inner workings of the cell to sense and respond to signals outside of the cell. Each surface receptor is specific with respect to the compound or compounds it will bind; a molecule that can bind to a given receptor is called a ligand for that receptor. When a ligand binds to its surface receptor, the internal portion of the receptor becomes modified in some manner, effectively communicating to the cell that the ligand is present. This then elicits some type of response, such as chemotaxis. ■ chemotaxis, p. 65. Cells can alter the types of surface molecules they make, enabling them to respond only to signals that are relevant when the cell is in a certain location or developmental stage. For example, a dendritic cell in the tissues would respond differently to certain stimuli than one that has migrated to ...
Signal Transduction: cell to cell communication (thing) by jandradt - Everything2.com
Signal transduction is a way that cells talk to one another. Cells communicate to coordinate what they do. They might be a group of cells al...
Biology Animations: Cell Communication Videos
Biology Animations includes selected, high quality biological animations; about cell biology, microbiology, genetics, immunology, cancer treatments and diagnosis.... ...
Cell Communication Flashcards
involves the G-linked receptor protein; when ligand binds, the GDP is dropped from the G protein and the GTP binds. The G protein then diffuses through the membrane to activating adenylate cyclase which converts ATP to cAMP. Protein kinase is then instructed to respond, resulting in celluar response. ...
Conjugation Bacterial- Hfr- Horizontan gene transfer- auxotroph
Conjugation, the transfer of DNA by direct cell-to-cell contact, depends on the presence of a conjugative plasmid(is small, double-stranded DNA molecules
Dr. Tony Pawson Inducted into Canadian Medical Hall of Fame - Mount Sinai Hospital - Toronto
A senior investigator and former director of the SLRI, Dr. Pawsons work has had a profound impact on biomedical research. His ground-breaking studies have focused on the signals that are transmitted between cells in the human body and how this forms a pattern of communication. By understanding cellular communication, scientists can track how the patterns of communication can break down in conditions such as heart disease and immune system deficiencies ...
Conexinas y sistema cardiovascular
SUAREZ, Jorge E. y BRAVO, Alicia I.. Conexins and the Cardiovascular System. Rev. argent. cardiol. [online]. 2006, vol.74, n.3, pp. 149-156. ISSN 1850-3748.. Intercellular communication is an essential biologic event of multicellular organisms and is associated with cell growth and differentiation control, apoptosis, adaptive responses of differentiated cells and the synchronization of cellular functions. A kind of intercellular junctions known as gap junctions, actively participate in these processes and are structurally made of conexins. From a cardiovascular viewpoint, cell to cell communication, under normal conditions, is essential in cardiac embryogenesis, electrical impulse transmission, synchronization of cardiac contractile activity, transmission of vascular reflex signals and other biological functions. Under pathological conditions, either by inherited or acquired genetic mutation, intercellular communications participate in the development of congenital cardiopathies, ...
pub H-BRS | Search
O-Glycosylation in general has impact on a diversity of biological processes covering cellular aspects (targeted transport of glycoproteins), molecular aspects (protein conformation, resistance to proteolysis), and aspects involved in cellular communication (cell-cell and cell-matrix interaction ...
Regenerative Medicine, Cell Bilology. With the recent progress in organ transplantation technology and stem-cell research, the practical application of regenerative therapy using stem cell-derivatives has come to public attention. To increase the feasibility of this new concept, however, kinetics and the functional expression of engrafted cells should be strictly controlled in well- organized 3-D tissues. So far, many researches have elucidated part of molecular mechanisms underlying the tissue morphogenesis to accumulate background information for successful cell transplantation. They include: 1) how nascent cells differentiate into functional ones;2) how they establish the proper polarity and the cell-cell junctional apparatus that enable cellular communications,;3) how they arrange functional multicellular structures; and 4) how they determine the overall size and control the shape of the tissue. All such dynamic cellular behaviors are known to be directed by the concerted action of many ...
Impact of the Immune System on the Brain and Mental Health | Side Effects
Most are aware that neurons send neurotransmitter signals to each other in circuits within the brain. My new book, The Secret Language of Cells, shows that similar conversations occur among all the cells in the body and these wide ranging conversations determine all physiological functions. While there are numerous examples of this cellular communication in the book - such as capillary cells sending directional signals for white blood cells to find an infection and capillaries instructing stem cells how to produce particular cells for the brain, this article will focus on a few ways that cellular conversations among immune cells and brain cells affect mental health. Two-way cellular conversations between traveling immune cells and stationary brain cells use signals that are sent as molecules, or molecules inside sacs, that are secreted into tissues, blood vessels, and cerebrospinal fluid. The signals can profoundly affect general cognition and memory, and are highly related to depression and ...
Technology - DC4U Technologies
Antigen based immunotherapeutics aim to rehabilitate the immune system and prepare the human body to concur disease. Key factor in this biological process is the immune response via dendritic cells (DCs) that either turn on the immune response or actively dampen unwanted immune inflammation. Current antigen based therapies however still lack an effective response which is potent, antigen specific and durable, and can also rely on a favorable safety profile. Therefore, there is a clear need for improvements in this therapeutic class. GlycoDCTM dendritic cell targeting technology. The core of DC4Us proprietary GlycoDCTM technology is glycation of antigens to which we direct the immune response. Glycans are complex carbohydrate structures that form recognition elements for glycan-specific receptors that, upon recognition, mediate cellular communication. The immuno-therapeutics that can be developed using the GlycoDCTM technology, are exceptional because they are potent, specific, durable, ...
Patent US6141546 - Mobile telephone systems - Google Patents
In a mobile cellular communication system, adjacent basestations BS1-BS4 are assigned different selections of different frequency channels to communicate with mobiles in their cells (10, etc.). To improve system quality and capacity, a basestation selects a frequency channel which is not assigned to it or any neighbour station, and makes test communications on that frequency channel with mobiles (e.g. MS1) in its cell. The basestation assesses the potential performance of that frequency channel, and neighbour basestations can monitor for potential interference on that frequency channel. The information so gathered can be analysed by an operations maintenance station OMC.
Application Note 129: AZ1395 small molecule targeting GPR39 - Biosensing Instrument
Membrane proteins play critical roles in cellular communications and are the most popular drug targets, accounting for over a half of the FDA approved drugs. One particularly important example of membrane proteins is G protein coupled receptors (GPCRs), which constitute the largest and most diverse protein family in the human genome with over 800 members identified to date. GPCRs are responsible for numerous cellular and physiological processes, including cell proliferation, differentiation, neurotransmission, development and apoptosis, and cancer growth and development.  Unsurprisingly, GPCRs are the largest family of membrane protein drug targets. A key task in studying the physiological functions of GPCRs and developing drugs targeting GPCRs is to measure the binding kinetics of ligands with GPCRs.. GPR39 receptor was studied against 3,4-bis-(2-imidazol-1-ylethoxy)-benzonitrile (AZ1395)  using SPRm 200. The GPR39 receptor is expressed in metabolic tissues including pancreatic ...
A Networking Paradigm Inspired by Cell Communication Mechanisms: Engineering Book Chapter | IGI Global
A Networking Paradigm Inspired by Cell Communication Mechanisms: 10.4018/978-1-4666-5125-8.ch002: This chapter provides a brief review of molecular communication, a networking paradigm inspired by cell communication mechanisms. In molecular communication
Junctional communication is induced in migrating capillary endothelial cells. | JCB
Using an in vitro model in which a confluent monolayer of capillary endothelial cells is mechanically wounded, gap junction-mediated intercellular communication has been studied by loading the cells with the fluorescent dye, Lucifer Yellow. Approximately 40-50% of the cells in a nonwounded confluent monolayer were coupled in groups of four to five cells (basal level). Basal levels of communication were also observed in sparse and preconfluent cultures, but were reduced in postconfluent monolayers. 30 min after wounding, coupling was markedly reduced between cells lining the wound. Communication at the wound was partially reestablished by 2 h, exceeded basal levels after 6 h and reached a maximum after 24 h, at which stage approximately 90% of the cells were coupled in groups of six to seven cells. When the wound had closed (after 8 d), the increase in communication was no longer observed. Induction of wound-associated communication was unaffected by exposure of the cells to the DNA synthesis ...
Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles
In the 1980s, exosomes were described as vesicles of endosomal origin secreted from reticulocytes. Interest increased around these extracellular vesicles, as they appeared to participate in several cellular processes. Exosomes bear proteins, lipids, and RNAs, mediating intercellular communication be …
SA node cell to atrial cardiac muscle cell communication Antibodies | Invitrogen ...
Antibodies for proteins involved in SA node cell to atrial cardiac muscle cell communication pathways, according to their Panther/Gene Ontology Classification
Brain cell communication findings pave way for new therapies - Healthcanal.com : Healthcanal.com
The researchers believe targeting the mechanism may lead to new therapies for the symptoms of motor neurone disease.. Otago neurobiologist Associate Professor Ian McLennan and his Aberdeen colleagues have discovered that a protein known as transforming growth factor beta 2 (TGF-β2) appears to regulate how motor neurons send signals to neighbouring brain cells.. Their findings are newly published in the prestigious US journal Proceedings of the National Academy of Sciences (PNAS).. Associate Professor McLennan says the discovery of the TGF-β2proteins previously invisible role in regulating brain cell communication surprised the team.. We did not predict this, and the finding fundamentally alters our understanding of how communication between cells in the brains motor system is controlled. It is also likely that this mechanism plays a role in other brain signalling systems.. Historically it was thought that the information flow from cell to cell was controlled by the number of quanta, or ...
Model of the role of FGF in establishing regional diffe | Open-i
Model of the role of FGF in establishing regional differences in gap junction-mediated intercellular communication in the lens. (A) The concentration of FGF i
Mapping intercellular communication networks with scRNA-seq - Scipio
One of the possible applications of single-cell sequencing data is to map potential communication between cell (sub-)types, which can be depicted as intercellular communication networks. These networks can yield detailed insight into the role of different cell types and processes within the complex system of cellular communication during various biological states such as development or disease.
Pancreatic acinar cells: the effect of carbon dioxide, ammonium chloride and acetylcholine on intercellular communication | Meta
1. Segments of mouse pancreatic or exorbital lacrimal gland were superfused with saline solutions. Under visual control two micro-electrodes were inserted into neighbouring cells within the same acinus or into neighbouring acini. Cell to cell electrical coupling was assessed by injecting rectangular current pulses through one electrode and measuring the electrotonic potential change in the same cell (V(1)) and in the neighbouring cell (V(2)). Acetylcholine (ACh) was added locally to impaled acini by micro-ionophoresis from an extracellular micropipette.2. Exposure of the tissues to a Krebs solution equilibrated with 100% CO(2) caused a rapid increase in the size of electrotonic potential changes in the current injection cell and disappearance of the electrotonic potential changes in a neighbouring acinus or cell. This electrical uncoupling of previously coupled cells was rapidly reversible upon return to a solution equilibrated with 95% O(2) and 5% CO(2).3. Reduction of electrical intercellular ...
New mode of cellular communication discovered in the brain
16.07.2013 Researchers at Johannes Gutenberg University Mainz (JGU) have discovered a new form of communication between different cell types in the brain. Nerve cells interact with neighboring glial cells, which results in a transfer of protein and genetic information. Nerve cells are thus protected against stressful growth conditions. The study undertaken by the Mainz-based cell biologists shows how reciprocal communication between the different cell types contributes to neuronal integrity. Their results have been recently published in the journal PLOS Biology. Brain function is determined by the communication between electrically excitable neurons and the surrounding glial cells, which perform many tasks in the brain. Oligodendrocytes are a type of glial cell and these form an insulating myelin sheath around the axons of neurons. In addition to providing this protective insulation, oligodendrocytes also help sustain neurons in other ways that are not yet fully understood. If this support ...
Harald Janovjak - Neurosciences - FBN
Abstract :. The development and function of multicellular organisms relies on the ordered communication of cells that function in networks and circuits. Our understanding of cellular communication and its physiological consequences hinges on the ability to modulate specific signals while monitoring effects in intact tissues and behaving animals. In our laboratory, we combine synthetic biology and cell biology to modulate the communication between cells and ultimately intervene with physiology. To achieve this goal, we re-engineer molecular components of the mammalian cellular communication machinery, currently in particular those components that control cell survival, to be responsive to new synthetic stimuli. These stimuli are novel ligands or, more recently, light in optogenetics, which offers control in space and time. For instance, we have recently developed receptor tyrosine kinases, such as the receptors for neurotrophic factors or EGF, that are activated by blue or red light in the ...
BB hangs up on cell tower planner | Anna Maria Island News
The strained relationship between Bradenton Beach and the Center for Municipal Solutions came to an end Feb. 8 with notification the city will repeal its cellular communications tower ordinance.. CMSs Lawrence Rusty Monroe and the city have been feuding for months over language in the ordinance drafted by Monroe and adopted May 5, 2011, under former Mayor Bob Bartelts administration.. As the city moved forward with discussions on installing a cellular communications tower near the public works facility last year, Commissioner Ric Gatehouse observed several issues in the ordinance he found objectionable.. The relationship between the city and Monroe became brittle and shattered at one point, with Monroe withdrawing - saying he would take his ordinance with him.. Monroe said the city had no rights to use his ordinance without agreeing to pay exclusive application review fees to his company, as per the original agreement outlined in his ordinance.. Gatehouse initially wanted the ordinance ...
Leukemia cell to endothelial cell communication via exosomal miRNAs | Read by QxMD
Recent findings indicate that specific microRNAs (miRNAs), such as those of the miR-17-92 cluster, may be responsible for regulating endothelial gene expression during tumor angiogenesis. Secreted miRNAs enclosed in exosomes also have an important role in cell-cell communication. To elucidate whether miRNAs secreted from neoplastic cells transfer into endothelial cells and are functionally active in the recipient cells, we investigated the effect of exosomal miRNAs derived from leukemia cells (K562) on human umbilical vein endothelial cells (HUVECs). As K562 cells released the miR-17-92 cluster, especially miR-92a, into the extracellular environment, K562 cells, transfected with Cy3-labeled pre-miR-92a, were co-cultured with HUVECs. Cy3-miR-92a derived from K562 cells was detected in the cytoplasm of HUVECs, and the Cy3-miR-92a co-localized with the signals of an exosomal marker, CD63. The expression of integrin α5, a target gene for miR-92a, was significantly reduced in HUVECs by exosomal ...
A plasma membrane protein is involved in cell contact-mediated regulation of tissue-specific genes in adult hepatocytes. | JCB
We have identified the liver-regulating protein (LRP), a cell surface protein involved in the maintenance of hepatocyte differentiation when cocultured with rat liver epithelial cells (RLEC). LRP was defined by immunoreactivity to a monoclonal antibody (mAb L8) prepared from RLEC. mAb L8 specifically detected two polypeptides of 85 and 73 kD in immunoprecipitation of both hepatocyte- and RLEC-iodinated plasma membranes. The involvement of these polypeptides, which are integral membrane proteins, in cell interaction-mediated regulation of hepatocytes was assessed by evaluating the perturbing effects of the antibody on cocultures with RLEC. Several parameters characteristic of differentiated hepatocytes were studied, such as liver-specific and house-keeping gene expression, cytoskeletal organization and deposition of extracellular matrix (ECM). An early cytoskeletal disturbance was evidenced and a marked alteration of hepatocyte functional capacity was observed in the presence of the antibody, ...
Search Results for tumour cell-tumour cell communication | Sciendo
The review describes the role of cells of extracellular matrix (ECM) as a source of neoplastic outgrowths additional to the original tumour. The cells undergo a spontaneous transformation or stimulation by the original tumour through intercellular signals, e.g. through Shh protein (sonic hedgehog). Additionally, cells of an inflammatory infiltrate, which frequently accompany malignant tumours and particularly carcinomas, may regulate tumour cell behaviour. This is either by restricting tumour proliferation or, inversely, by induction and stimulation of the proliferation of another tumour cell type, e.g. mesenchymal cells. The latter type of tumour may involve formation of histologically differentiated stromal tumours (GIST), which probably originate from interstitial cells of Cajal in the alimentary tract. Occasionally, e.g. in gastric carcinoma, proliferation involves lymphoid follicles and lymphocytes of GALT (gut-associated lymphoid tissue), which gives rise to lymphoma. The process is ...
Anti-Integrin β5 antibodies, human - Primary antibodies - Antibodies - MACS Flow Cytometry - Products - Miltenyi Biotec -...
Clone REA718 recognizes the human integrin β5 antigen, a 95 kDa glycoprotein single-pass type I membrane protein. Integrins are a family of transmembrane receptors that mediate adhesion of cells to extracellular matrices, as well as intercellular interactions. These interactions transduce signals that control complex cell functions such as proliferation, differentiation, and survival, and require the regulation of gene expression. Integrins are heterodimeric glycoprotein receptors and exist as non-covalently bound α and β subunits. The integrin αV/β5 heterodimer is found on many types of tissue cells, such as epithelial cells, endothelial cells, keratinocytes, and osteoblastic cells. It is a receptor for fibronectin and vitronectin and acts as a receptor for adenovirus type C. Additional information: Clone REA718 displays negligible binding to Fc receptors. - Nederland
Anti-Integrin β5 antibodies, human - Primary antibodies - Antibodies - MACS Flow Cytometry - Products - Miltenyi Biotec -...
Clone REA718 recognizes the human integrin β5 antigen, a 95 kDa glycoprotein single-pass type I membrane protein. Integrins are a family of transmembrane receptors that mediate adhesion of cells to extracellular matrices, as well as intercellular interactions. These interactions transduce signals that control complex cell functions such as proliferation, differentiation, and survival, and require the regulation of gene expression. Integrins are heterodimeric glycoprotein receptors and exist as non-covalently bound α and β subunits. The integrin αV/β5 heterodimer is found on many types of tissue cells, such as epithelial cells, endothelial cells, keratinocytes, and osteoblastic cells. It is a receptor for fibronectin and vitronectin and acts as a receptor for adenovirus type C. Additional information: Clone REA718 displays negligible binding to Fc receptors. - Lëtzebuerg
CD95 Rabbit Polyclonal Antibody (ER1902-56) - HUABIO
Cytotoxic T lymphocyte (CTL)-mediated cytotoxicity constitutes an important component of specific effector mechanisms in immuno-surveillance against virus-infected or transformed cells. Two mechanisms appear to account for this activity, one of which is the perforin-based process. Independently, a FAS-based mechanism involves the transducing molecule FAS (also designated APO-1) and its ligand (FAS-L). The human FAS protein is a cell surface glycoprotein that belongs to a family of receptors that includes CD40, nerve growth factor receptors and tumor necrosis factor receptors. The FAS antigen is expressed on a broad range of lymphoid cell lines, certain of which undergo apoptosis in response to treatment with antibody to FAS. These findings strongly imply that targeted cell death is potentially mediated by the intercellular interactions of FAS with its ligand or effectors, and that FAS may be critically involved in CTL-mediated cytotoxicity.. ...
3D Cell Culture Industry Worth USD 1.69 billion by 2024 - Market Analysis By Technology, Application, End Use & Forecasts...
The global 3D cell culture market is anticipated to reach USD 1.69 billion by 2024, according to a new report by Grand View Research, Inc. Potential of this technology to replace and reduce the usage of animal models for histological analysis and biochemical assays is expected to fuel demand for 3D cell culture products thus driving growth in the coming years.. Advent of technology with respect to spheroid formation and matured assay methods is expected to boost the emergence of 3D optimized assays, kits, and protocols, in turn, expediting the entire research process. In addition, the scope of three-dimensional (3D) cell culturing experiments for evaluation of drug moiety is anticipated to grow owing to advantages associated with its usage. These advantages include increased cell to extra cellular matrix (ECM) as well as intercellular interactions, variation in the proliferation zones, ease for analyzing impact of site-specific stromal tissue components in the tumor microenvironment.. Research ...
Effective method for correcting various CNS pathologies developing under oxygen deficiency - Lobachevsky University
Hypoxia is a key factor that accompanies most brain pathologies, including ischemia and neurodegenerative diseases. Reduced oxygen concentration results in irreversible changes in nerve cell metabolism that entails cell death and destruction of intercellular interactions. Since neural networks are responsible for the processing, storage and transmission of information in the brain, the loss of network elements can lead to dysfunction of the central nervous system and, consequently, the development of neurological deficiency and the patients severe disability.. This is the reason why the worlds neurobiological community is currently involved in an active search for compounds that can prevent the death of nerve cells and support their functional activity under stress.. According to Maria Vedunova, Director of the Institute of Biology and Biomedicine at Lobachevsky University (UNN), the Institutes researchers propose to use the bodys own potential to combat hypoxia and its consequences.. Our ...
Student influence upon the teacher: three case studies and their theoretical implications for a bidirectional interaction model...
The purpose of this study was to examine student influence upon the teacher within the context of a bidirectional model of interaction. The possibility of using the teachers motivational structure as a means of explaining and predicting the occurence of student influence was also considered. -- The theoretical framework for the study was developed from a review of the literature. The key components of the model were: the teachers predispositions, including their motivational structure, the objective situation, and the definition of the situation. Presumably, the teachers behavior would be controlled by their definition of the situation, which would be a function of the predispositional structure and the objective situation. -- The interaction between the teacher and the students in three elementary classrooms was studied. These teachers were chosen from a sample of 54 teachers, who had first been categorized into three groups, on the basis of a Q-Sort. Thus, there was one teacher to represent ...
Evolutionary Biology: Cell-Cell Communication, and Complex Disease | Cell Biology | Cell & Molecular Biology | Life Sciences |...
Preface xi About the Authors xiii. 1 THE CELLULAR ORIGIN OF VERTEBRATES 1. The Origins of Unicellular Life on Earth 1. Prokaryotes versus Eukaryotes 4. Coevolution of traits 5. Cholesterol Facilitates Lipid Rafts for Cell-Cell Communication 7. The Endomembrane System 9. The Cellular Mechanism of Evolution 10. Why Evolve? 11. Cell-Cell Communication and Aging 12. 2 REDUCING LUNG PHYSIOLOGY TO ITS MOLECULAR PHENOTYPES 17. Hormonal Acceleration of Lung Development 17. Neutral Lipid Traffi cking and Lung Evolution 19. Other Examples of Cellular Cooperativity 23. Summary 24. 3 A CELL-MOLECULAR STRATEGY FOR SOLVING THE EVOLUTIONARY PUZZLE 25. Rationale for Cell-Molecular Evolution 25. Mechanism of Mammalian Lung Development 28. Avian Lung Structure-Function Relationship: The Exception that Proves the Rule 32. Does Ontogeny Recapitulate Phylogeny? The Role of PTHrP in Lung Development 32. Interrelationship between PTHrP, Development, Physiology, and Repair: Is Repair a Recapitulation of Ontogeny and ...
Answer Key Cell Communication Webquest Answers
There are two pages in this section to help you and your learners: Project Based Learning (Page 1 of 2): An essay. Start studying cell reproduction worksheet. Students can toggle between two different views of the cell cycle by pressing the text in the center of the graphic. Animal Systems I. 3 Stoichiometry Webquest Answer Key. Helens School District. Background: The endocrine system is a complex network of glands, hormones and receptors. Click DNA to Protein and try the interactive activities Build a DNA Molecule & Transcribe and Translate a Gene 5. 2 Introduction to Signal Transduction4. Tkt Is Taken As A Series Of Multiple-Choice Tests. To give you an idea about size, the length of a key on the keyboard is about 1 cm. The diagram below is of a nerve cell or neurone. is able to correctly answer word problems, but is unable to explain how he/she got the answer. •Movement of gases, liquids, and solids. For the years , Monsanto was Steins office. Key Indicators 1) What is carbon dioxide ...
An astounding find reveals a rare cause of epilepsy - India Education | Latest Education News | Global Educational News |...
Researchers at The University of Queensland, working to gain a better understanding of how brain cells work, have discovered the underlying mechanism of a rare genetic mutation that can cause epilepsy.. Dr Victor Anggono from UQs Queensland Brain Institute said his team made the ground-breaking findings while researching nerve cell communications, which are an important process in normal brain function.. Were both excited and astounded to make such an important contribution to the field of cellular and molecular neuroscience, Dr Anggono said.. He stressed that the mutation was extremely rare, with only one reported case in the world to date.. Dr Anggonos team studied protein structures, called receptors, that are attached to cell surfaces to make the discovery.. It turns out that this particular mutation causes receptors in brain cells to behave differently, resulting in an imbalance in brain cell communication - and that can lead to disorders, he said.. For example, cells that talk ...
Berkmen - OpenWetWare
Bacterial mating or conjugation is the transfer of DNA from one bacterium to another via direct cell-to-cell contact through a mating pore. My current research uses the genetically-tractable bacterium Bacillus subtilis as a model system to explore the function and subcellular localization of a putative component of the bacterial mating pore apparatus. I have been characterizing the protein ConE (formerly YddE) which is encoded on the B. subtilis conjugal element ICEBs1. ConE is related to proteins encoded on conjugal elements in numerous bacteria, including the Gram-positive pathogens S. aureus, C. difficile, and L. monocytogenes. ConE belongs to a large superfamily of ATP-dependent pumps involved in the extrusion of proteins and DNA through membrane pores. I have shown that ConE and its ATPase domain are essential for mating of ICEBs1. In addition, ConE-GFP localizes at the cell poles, in close association with the membrane (see Figure). Given ConEs localization, ATPase domain, and ...
Difference between revisions of Berkmen - OpenWetWare
Bacterial mating or conjugation is the transfer of DNA from one bacterium to another via direct cell-to-cell contact through a mating pore. My current research uses the genetically-tractable bacterium Bacillus subtilis as a model system to explore the function and subcellular localization of a putative component of the bacterial mating pore apparatus. I have been characterizing the protein ConE (formerly YddE) which is encoded on the B. subtilis conjugal element ICEBs1. ConE is related to proteins encoded on conjugal elements in numerous bacteria, including the Gram-positive pathogens S. aureus, C. difficile, and L. monocytogenes. ConE belongs to a large superfamily of ATP-dependent pumps involved in the extrusion of proteins and DNA through membrane pores. I have shown that ConE and its ATPase domain are essential for mating of ICEBs1. In addition, ConE-GFP localizes at the cell poles, in close association with the membrane (see Figure). Given ConEs localization, ATPase domain, and ...
bacterial transformation powerpoint
PPT - Bacterial Transformation PowerPoint presentation , free to view - id: 14d701-NGYwZ. Conjugation (bacterial sex) involves the exchange of DNA through direct cell-to-cell contact or through a bridge-like connection between two cells called a sex pilus. preparation for the pglo lab. After transformation, the cells may express the acquired genetic information, which may serve as a source of genetic diversity and potentially provide … chapter 3. content. partnership for health and wholeness benjamin v. lozare, ph.d johns hopkins, BACTERIAL MENINGITIS - . Bacteria are used to copy DNA and make desired proteins . abe lab sequence. What if nothing grows on either LB plate? Transformation is a key process in molecular cloning, by which multiple copies of recombinant DNA molecules are produced. • Changing the genes and phenotype of a bacteria by uptake of foreign/new DNA • a natural process that bacteria have evolved in order to obtain DNA from their environment. • If so, did the gene of ...
Help to go: T cells transfer CD40L to antigen-presenting B cells. - Nuffield Department of Orthopaedics, Rheumatology and...
Most immune cell communication takes place by intercellular transfer of cytokines or the contact-dependent interaction of surface receptors in immunological synapses. In this issue of the European Journal of Immunology, Gardell and Parker (Eur. J. Immunol. 2017, 47, 41-50) point to a new, hybrid mechanism for Th1-cell delivery of help to B cells, based on contact-dependent CD40L transfer. The transfer process and its specificity are both cell contact dependent and antigen dependent. CD40 expression is also required on the B-cell surface to capture the CD40L presented by the Th1 cell. While further studies are needed to confirm the phenomenon in vivo and to test the role of transferred CD40L in other aspects of T-cell help, this study provides an exceptional take-off point and makes excellent use of mouse genetics to work out some possible rules for B cells being able to order help to go.
Supplementary MaterialsSupplementary Figures S1, S2 and S3 41598 2018 31569 MOESM1 ESM. lymphocyte proliferation and - Novel...
Supplementary MaterialsSupplementary Figures S1, S2 and S3 41598_2018_31569_MOESM1_ESM. lymphocyte proliferation and activation in response to Concanavalin A. Transwell experiments demonstrated that this was predominantly due to direct cell-cell contact in addition to soluble mediators whereby CDCs produced high levels of PGE2 under inflammatory conditions. This led to down-regulation of CD25 expression on lymphocytes via the EP4 receptor. Blocking prostaglandin synthesis restored both, proliferation and activation (measured via CD25 expression) of stimulated lymphocytes. We demonstrated for the first time in a large animal model that CDCs inhibit proliferation in allo-reactive lymphocytes and have potent immunosuppressive activity mediated via PGE2. Introduction Cardiac disease is a significant cause of death in humans, accounting for around 25% of all causes of mortality1. Recognition that the heart is capable of regeneration2, has raised considerable interest over BSF 208075 inhibition the ...
Alternative Promoter use Governs the Expression of IgLON Cell Adhesion Molecules in Histogenetic Fields of the Embryonic Mouse...
The members of the IgLON superfamily of cell adhesion molecules facilitate fundamental cellular communication during brain development, maintain functional brain circuitry, and are associated with several neuropsychiatric disorders. Usage of alternative promoter-specific 1a and 1b mRNA isoforms in Lsamp, Opcml, Ntm and the single promoter of Negr1 in the mouse and human brain has been previously described. To determine the precise spatiotemporal expression dynamics of Lsamp, Opcml, Ntm isoforms and Negr1, in the developing brain, we generated isoform-specific RNA probes and carried out in situ hybridization in the developing (embryonic, E10.5, 13.5, 17; post natal, P0) and adult mouse brains. We show that promoter-specific expression of IgLONs is established early during pallial development (at E10.5), where it remains throughout its differentiation through adulthood. In the diencephalon, midbrain and hindbrain, strong expression patterns are initiated a few days later and begin fading after birth,
In the present work, we report evidence that in addition to its role on the proliferation of pancreatic progenitor cells, the mesenchyme is crucial in controlling the timing of pancreatic β-cell differentiation. When we cultured rat embryonic pancreatic epithelium in the absence of its surrounding mesenchyme, we found that Ngn3 expression was turned on rapidly and then turned off a few days later, in keeping with the reported in vivo pattern (15,25). Our filter-separation experiments indicate that the mesenchyme-induced delay in Ngn3 induction requires direct contact between the epithelium and the mesenchyme. This result fits in with recent data indicating that direct cell-cell contact between epithelial and mesenchymal cells suppresses β-cell formation (26). We also found that Ngn3 expression occurred far earlier without mesenchyme, within a few hours compared with 3 days with mesenchyme either in vitro or in vivo. This acceleration in Ngn3 induction resembles the pancreatic phenotype of mice ...
Mapping the Human Adipose Tissue Cells and Intercellular Communication - Chan Zuckerberg Initiative
This network will characterize the single nucleus transcriptomes and intercellular communication networks of human adipose tissue cells (adipocytes and stroma-vascular cells) across fat depots, sex, and ethnicity.
Wonky Waves Allow Cancer Cells To Spread - ScienceAGoGo
The waves are said to be produced in direct response to the presence of epidermal growth factor (EGF), and last approximately 10 - 20 minutes before vanishing. Wave cells have become a hot topic of late, as researchers suspect that they play an important role in the transmission and regulation of normal cellular communication.. Under normal circumstances, waves are responsible for selectively collecting growth-promoting proteins and directing them into the inner structure of the cell. This process results in a reorganization of the cells outer infrastructure, where it forms a flexible foot-like structure (lamellipodia) which then allows the cell to move and dock with corresponding epidermal growth factor receptors (EGFR). Usually, the wave neutralizes or moderates the internalized growth protein, but in cancer cells, where the wave is either malfunctioning or not present, metastatic cancer occurs as a result of unregulated EGF and EGFR interaction.. These findings have broad implications ...
Team Laura Brion | Department of Medicine, Solna | Karolinska Institutet
Signal transduction is the molecular basis for cellular communication. Complex networks of intracellular molecules enable cells to receive signals from their environment and to modify their behavior in response to these signals. Signaling molecules are interconnected, and depending on how they are linked together they can form different types of networks. We have recently described a novel network of proteins that becomes activated by increases in cell sodium permeability and that regulates active sodium transport. Because each component of this sodium-sensing network so far described have been independently associated with multiple and essential cell functions, our work on the network topology and modeling is of importance because it will help us to understand the networks role and complexity when transforming the sodium signal into transcription activation and gene expression leding to changes in myocardial- and/or renal cells growth.. Also, understanding the function and relevance of the ...
Q&A with Maliha Aqeel, Director of Global Communications at Fix Network World
Maliha Aqeel, Director of Global Communications at Fix Network World is an award-winning, communication and marketing professional who helps companies harness the power of their brand to drive engagement and achieve measurable business results. She has developed and...
Results Of Emerging Technologies On The Society | Y-Framework
Cell phone is a protracted-vary, transportable electronic machine used for cellular communication. Dad and mom use the GPS system to keep track of their youngsters. Theyll set up digital boundaries on the app so it alerts them when their little one crosses that line. Cell phone firms offer the service for an extra charge as a solution to make extra revenue. Lately a mobile phone can give place to various applications coming from numerous genres. These embrace social networking purposes (Fb, Twitter, hi5, MySpace and so on.), gaming purposes, cell office applications, all chatting purposes (yahoo, gtalk, msn and so forth.) and plenty of such others as effectively. These applications carry loads of significance too as these had opened a brand new dimension of communication.. Judd Heape, a Qualcomm vp for product management, says the cell chip chief couldnt embody AV1 technology within the new chip due to schedule and value considerations. Qualcomm chips will finally support AV1, he mentioned, ...
Localized signaling islands in cells: New targets for precision drug design - Scienmag: Latest Science and Health News
Dr. John D. Scott, professor and chair of pharmacology at the University of Washington School of Medicine and a Howard Hughes Medical Institute Investigator, along with Dr. F. Donelson Smith of the UW and HHMI, led this study, which also involved Drs. Claire and Patrick Eyers and their group at the University of Liverpool.. The researchers explained that key cellular communication machinery is more regionally constrained inside the cell than was previously thought. Communication via this vital system is akin to social networking on your Snapchat account.. Within a cell, the precise positioning of such messaging components allows hormones, the bodys chief chemical communicators, to transmit information to exact places inside the cell. Accurate and very local activation of the enzyme that Scott and his group study helps assure a correct response occurs in the right place and at the right time. The inside of a cell is like a crowded city, said Scott, It is a place of construction and tearing ...
Targeting tumor growth
The platelet-derived growth factor-ß (PDGF-ß) intracellular signaling pathway has an established role in mediating cellular communication between endothelial and mural cells, which is essential for the normal formation of blood vessels. Dr. Weiss and colleagues have discovered that MT1-MMP, whose traditional role in endothelial and mural cells is to break down the proteins that reside in the spaces between cells, has an additional role in the regulation of PDGF-ß signaling ...
Cell Communication and Adhesion provides a central forum for the rapid publication of full-length manuscripts, short communications, reviews and conference reports of high quality, covering all aspects of receptor-based cell recognition and signaling. This includes research directed toward an understanding of the molecular basis of cell behavior as influenced by the interaction of cells with one another and with the extracellular environment, including extracellular matrix, cytokines and chemotactic factors. This journal provides a single source of information concerning all forms of intercellular communication, intercellular junctions and families of adhesion receptors and counter receptors from diverse biological systems. Manuscripts will be accepted describing the role of intercellular signaling, junctions and adhesion pathways in pathological and normal processes, ranging from fundamental interactions in developing systems to immune- based recognition events and neuronal targeting. Research ...
At the Redenti Lab, we are exploring cellular communication involved in the development and regeneration of retinal and other central nervous system tissue. We are particularly interested in how cells respond to morphogenetic fields of discrete, localized biochemical and electrical signals leading to the development of organized neural tissue. Read More ...
Products: Is This The Missing Link In Human…..Nutrition?
Mannatechs Ambrotose complex is the worlds first dietary supplement to combine a scientifically proven and standardized blend of plant sourced glyconutrients.. What are Glyconutrients?. Good question glad you asked. Glyconutrient saccharides make up what is called a Glycoprotein. These attach themselves to cell membranes massively increasing the cells abilities to talk to each other. Improving the efficiency of all the bodies systems.. O.K. thats the sciencey stuff out of the way so what does that actually mean for you and your familys health?. A lot. Third party clinical trials have shown that due to improved cellular communication, you get improved cognitive function. This means better memory and concentration. Improved moods and less irritability. Boosts to the immune system, and support for proper organ function. And a more efficient digestive system. Ambrotose complex helps you build a strong foundation for better wellbeing, at the cellular level.. Where does Mannatechs Ambrotose ...
Scientists reveal new avenue for drug treatment in neuropathic pain
New research from Kings College London has revealed a previously undiscovered mechanism of cellular communication, between neurons and immune cells, in neuropathic pain.
RXRA related Antibodies, Proteins, cDNA and ELISA Kits- Cusabio
Cusabio offers RXRA related Antibodies, Proteins, cDNA and ELISA Kits. We also illustrate the related signaling pathways covering most research areas so that you can know the internal cellular communication. Some free antibody samples are given away in times.
Cerna home care releases OnHand Assistance, a smartwatch for seniors safety - Body Electron
Senior care service provider Cerna Home Care launched Onhand Assistance - a smartwatch especially designed for seniors. The stylish wearable device provides fall detection, fall notification, vitals monitoring, cellular communication, and medication reminders - in addition to life-saving calls and care. Every second an older adult fall, making falls the number one cause of injuries and deaths from injury among older Americans. In 2014 alone, 29 million falls among elderly Americans resulted in seven million injuries and costing an estimated $31 billion in annual Medicare costs, according to a new report published by the Centers for Disease Control and Prevention in this weeks Morbidity and Mortality Weekly Report (MMWR).. Onhand Assistance helps lessen the need for expensive personal caregivers and avoids time consuming ambulance trips to the hospital due to false alarms. Family members monitor their loved one through the Onhand Assistance smartphone app. Seniors, their friends and their ...
Cell Communication & Adhesion
... (formerly Cell Adhesion & Communication) is an academic journal that publishes review articles on ... Cell Communication & Adhesion homepage of Cell Communication & Adhesion (Articles with short description, Short description is ... Intercelluar communication Intercellular junctions Receptor-based cell recognition & signaling Cell Communication & Adhesion is ... FRACP are the regional editors of Cell Communication & Adhesion. Cell Communication & Adhesion publishes six issues per year in ...
Cell Communication and Signaling
... - Editorial Board Journal Citation Reports - Cell Communication and Signaling (Paywall) v t e ... has been the editor-in-chief of Cell Communication and Signaling since April 2008. In June 2012, Cell Communication and ... Cell Communication and Signaling is a peer-reviewed and open access scientific journal that publishes original research, ...
New Jersey Cybersecurity and Communications Integration Cell
The New Jersey Cybersecurity and Communications Integration Cell (NJCCIC), also known as the New Jersey Office of Homeland ... "NEW JERSEY CYBERSECURITY AND COMMUNICATIONS INTEGRATION CELL (NJCCIC) AND FS-ISAC PARTNER TO DELIVER CYBER THREAT INTELLIGENCE ... On July 8, 2015, the New Jersey Cybersecurity and Communications Integration Cell partnered with the Financial Services ... Governor Chris Christie signed an Executive order to establish the New Jersey Cybersecurity and Communications Integration Cell ...
... installs four 400kW fuel cells in California - The Hydrogen Journal Archived August 1, 2013, at the Wayback ... Cox Communications Partners with UTC Power to Install Fuel Cells in California - SOUTH WINDSOR, Conn., Feb. 7, 2011/PRNewswire ... Gardner, W. David (November 19, 2010). "Cox Communications Launches Cell Service". InformationWeek. Retrieved December 22, 2010 ... "Cox Communications - High Speed Internet services in Cox Communications". Cox.com. Retrieved June 22, 2012. "Cox moving 100 ...
In biology, cell signaling (cell signalling in British English) or cell communication is the ability of a cell to receive, ... Cell biology/Pollard et al, The Cell/ G.M. Cooper Cell biology/Pollard et al, The Cell/ G.M. Cooper Cooper GM (2000). " ... "The Inside Story of Cell Communication". learn.genetics.utah.edu. Retrieved 2018-10-20. "When Cell Communication Goes Wrong". ... Cell signaling, Cell biology, Cell communication, Systems biology, Human female endocrine system). ...
Cell Communication & Adhesion. 10 (1): 27-36. doi:10.1080/15419060302063. PMID 12881038. S2CID 225894. Wang WH, Yang JJ, Lin YC ... However, Cx29, which is highly expressed in myelin-forming glial cells of the CNS and PNS, has not been documented to form gap ... "Identification of novel variants in the Cx29 gene of nonsyndromic hearing loss patients using buccal cells and restriction ... "Connexin29 is uniquely distributed within myelinating glial cells of the central and peripheral nervous systems". The Journal ...
Civitelli, R (2008). "Cell-cell communication in the osteoblast/osteocyte lineage". Archives of Biochemistry and Biophysics. ... Adams, Dany S; Levin, Michael (2012). "Endogenous voltage gradients as mediators of cell-cell communication: Strategies for ... In non-excitable cells, the resting potential across the plasma membrane (Vmem) of individual cells propagate across distances ... Robinson, K. R (1985). "The responses of cells to electrical fields: A review". The Journal of Cell Biology. 101 (6): 2023-7. ...
Cell Communication & Adhesion. 16 (1-3): 15-27. doi:10.1080/15419060903009329. PMID 19533476. S2CID 19077857. Kirchner F, ... Plakophilin-2 over time has shown to be more than components of cell-cell junctions; rather the plakophilins are emerging as ... Cell. Proteomics. 4 (6): 785-95. doi:10.1074/mcp.M500021-MCP200. PMID 15778465. Kimura K, Wakamatsu A, Suzuki Y, Ota T, ... Cell Genet. 88 (3-4): 286-7. doi:10.1159/000015540. PMID 10828611. S2CID 35411706. Hofmann I, Mertens C, Brettel M, Nimmrich V ...
Tandem mass spectrometry
Gafken PR, Lampe PD (2006). "Methodologies for characterizing phosphoproteins by mass spectrometry". Cell Communication & ... Tandem mass spectrometry cannot be applied for single-cell analyses as it is insensitive to analyze such small amounts of a ... TMT reagents can be used to simultaneously analyze 2 to 11 different peptide samples prepared from cells, tissues or biological ... Fragments observed by EISA have higher signal intensity than traditional fragments which suffer losses in the collision cells ...
... which allow for gap junction intercellular communication (GJIC) between cells to regulate cell death, proliferation, and ... Furthermore, GJA1 is expressed in many immune cells, such as eosinophils and T cells, where its gap junction function promotes ... In addition, GJA1 can be found in the Leydig cells and seminiferous tubules between Sertoli cells and spermatogonia or primary ... Cell Communication & Adhesion. 10 (4-6): 201-205. doi:10.1080/cac.10.4-6.201.205. PMID 14681016. Harris AL, Locke D (2009). ...
... cell junctions help hold animal cells together. Cell junctions are also especially important in enabling communication between ... Cell junctions are also important in reducing stress placed upon cells. In plants, similar communication channels are known as ... ISBN 978-1-4160-2973-1. Bloemendal, S; Kück, U (January 2013). "Cell-to-cell communication in plants, animals, and fungi: a ... Loss of this adhesion effects cell structure, cellular functioning and communication with other cells and the extracellular ...
Pioneer of Cell-Matrix Interactions". Cell Communication & Adhesion. 20 (6): 139. doi:10.3109/15419061.2013.857662. "Richard O ... His research focuses on cell adhesion and the interactions between cells and the extracellular matrix, with a particular ... Hynes served as the president of the American Society for Cell Biology in 2000. He has been a member of the Board of Governors ... In 2007, the American Society for Cell Biology awarded Hynes and Zena Werb their most prestigious award, the E.B. Wilson Medal ...
Cell Communication & Adhesion. 13 (3): 171-83. doi:10.1080/15419060600726183. PMID 16798616. Konshina AG, Boldyrev IA, Utkin YN ... though some members may cause physical damage to the cell by establishing pores in the cell membrane. Another class, called the ... Many members of the family are neurotoxins that bind to receptor proteins in the cell membrane, particularly nicotinic ... Nature Communications. 10 (1): 3642. Bibcode:2019NatCo..10.3642D. doi:10.1038/s41467-019-11639-2. ISSN 2041-1723. PMC 6692343. ...
Cell Communication & Adhesion. 17 (2): 48-54. doi:10.3109/15419061.2010.492535. ISSN 1541-9061. PMC 3285265. PMID 20560867. ... Another beneficial cell modification is the adjustment of substrate and growth requirements of a cell. By changing cell needs, ... changing cell growth and proliferation requirements, adding or removing cell functions, and many more. Cell engineering often ... improving monoclonal antibody production using engineered cells In vivo cell factories: engineering cells to produce ...
Kučera O, Cifra M (November 2013). "Cell-to-cell signaling through light: just a ghost of chance?". Cell Communication and ... The hypothesis of cellular communication by biophotons was highly criticised for failing to explain how could cells detect ... In healthy cells, the concentration of ROS is minimized by a system of biological antioxidants. However, heat shock and other ... One biophoton mechanism focuses on injured cells that are under higher levels of oxidative stress, which is one source of light ...
Cell Communication and Signaling. 9 (18): 18. doi:10.1186/1478-811X-9-18. PMC 3180438. PMID 21914164. Mantovani A (June 2010 ... For a normal cell to transform into a cancer cell, the genes that regulate cell growth and differentiation must be altered. The ... such as giant cell carcinoma, spindle cell carcinoma and small-cell carcinoma. An invasive ductal carcinoma of the breast (pale ... Germ cell tumor: Cancers derived from pluripotent cells, most often presenting in the testicle or the ovary (seminoma and ...
Cell Communication and Signaling. 7 (22): 22. doi:10.1186/1478-811X-7-22. PMC 2747914. PMID 19737390. Simister PC, Feller SM ( ... GC-GAP is responsible for the proliferation of astroglioma cells. The interaction between GAB2 and Grb2 at the cell membrane ... It is a member of the GAB/DOS family localized on the internal membrane of the cell. It mediates the interaction between ... PI3K activation by GAB2 promotes cell growth. The effects of all the pathways activated by GAB proteins are not known, but it ...
Cell Communication and Signaling. 18 (1): 181. doi:10.1186/s12964-020-00658-y. ISSN 1478-811X. PMC 7656774. PMID 33176800. ... Dunlap correctly predicted that single cells, including mammalian cells, can act as autonomous oscillators with their own ... Cell. 137(4): 749-60. doi: 10.1016/j.cell.2009.03.019 PMID 19450520 Larrondo, L.F.; Olivares-Yañez, C.; Baker, C.L.; Loros, J.J ... Cell. 137 (4): 749-760. doi:10.1016/j.cell.2009.03.019. ISSN 0092-8674. PMC 2718715. PMID 19450520. Hurley, Jennifer M.; ...
Heldin CH (2013). "Targeting the PDGF signaling pathway in tumor treatment". Cell Communication and Signaling. 11: 97. doi: ... In vitro studies using cultured cells indicate that endothelial cells secrete PDGF, which recruits PDGFRβ-expressing pericytes ... Olson LE, Soriano P (2011). "PDGFRβ signaling regulates mural cell plasticity and inhibits fat development". Developmental Cell ... Cell. Biol. 12 (12): 5824-33. doi:10.1128/MCB.12.12.5824. PMC 360522. PMID 1333047. Chen M, She H, Davis EM, Spicer CM, Kim L, ...
Cell Communication and Signaling. 10 (1): 34. doi:10.1186/1478-811X-10-34. PMC 3515343. PMID 23176204. Priolo, M.; Laganà, C ( ... The DLHP cells function in a similar fashion as MHP cells regarding their wedge like shape, however, the DLHP cells result in ... These special cells are called medial hinge cells (MHPs). As the ectoderm continues to elongate, the ectodermal cells of the ... The neural crest cells eventually pull the adjacent ectodermal cells together, which leaves neural crest cells between the ...
Cell Communication and Signaling. 20 (1): 8. doi:10.1186/s12964-021-00813-z. PMC 8756626. PMID 35022040. Horning MS, Trombley ... Granule cell precursors (GCPs) of the cerebellum, after undergoing symmetric cell division in the external granule-cell layer ( ... Two of these variable subunits, GluN2A and GluN2B, have been shown to preferentially lead to cell survival and cell death ... ions into the cell and potassium (K+) out of the cell. Ca2+ flux through NMDA receptors in particular is thought to be critical ...
... is a Src family kinase target in colorectal cancer cells". Cell Communication and Signaling. 6: 7. doi:10.1186/1478-811X-6-7. ... is a Src family kinase target in colorectal cancer cells". Cell Communication and Signaling. 6: 7. doi:10.1186/1478-811X-6-7. ... ODIN may be involved in cancer cell signaling mechanisms. In a study, 64 colorectal cancer cell lines were tested for their ... The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain". DNA ...
Cell Communication and Signaling. 7: 9. doi:10.1186/1478-811X-7-9. PMC 2685135. PMID 19389260. Nygaard G, Di Paolo JA, Hammaker ... Zou X, Tsutsui T, Ray D, Blomquist JF, Ichijo H, Ucker DS, Kiyokawa H (July 2001). "The cell cycle-regulatory CDC25A ... Chen J, Fujii K, Zhang L, Roberts T, Fu H (July 2001). "Raf-1 promotes cell survival by antagonizing apoptosis signal- ... Zhang L, Chen J, Fu H (July 1999). "Suppression of apoptosis signal-regulating kinase 1-induced cell death by 14-3-3 proteins ...
As such, succinate links TCA cycle dysfunction or metabolic changes to cell-cell communication and to oxidative stress-related ... Succinate may enhance adaptive immunity by triggering the activity of antigen-presenting cells that, in turn, activate T-cells ... Enzymes required for the GABA shunt are expressed in neurons, glial cells, macrophages and pancreatic cells. Succinate is ... Cell Communication and Signaling. 14: 3. doi:10.1186/s12964-016-0126-1. PMC 4709936. PMID 26759054. Bardella, Chiara; Pollard, ...
Developmental biologists suggest that complex interactions in genetic networks and communication among cells can lead to ... Before a cell divides through mitosis, the DNA is copied, so that each of the resulting two cells will inherit the DNA sequence ... Cell Communication and Signaling. 9 (30): 30. doi:10.1186/1478-811X-9-30. PMC 3215633. PMID 22053760. "Francis Galton (1822- ... However, this was disputed by the creation of the cell theory in the 19th century, where the fundamental unit of life is the ...
Li Y, Wang Z, Ajani JA, Song S (February 2021). "Drug resistance and Cancer stem cells". Cell Communication and Signaling. 19 ( ... A parent cell divides to form two daughter cells, and these daughter cells are used to build new tissue or to replace cells ... Cancer cells are cells that divide continually, forming solid tumors or flooding the blood with abnormal cells. Cell division ... Healthy cells stop dividing when there is no longer a need for more daughter cells, but cancer cells continue to produce copies ...
JAK-STAT signaling pathway
Cell Communication and Signaling. 10 (1): 32. doi:10.1186/1478-811X-10-32. PMC 3507883. PMID 23134684. Kiu, Hiu; Nicholson, ... For example, non-functional JAK3 causes SCID, which results in patients having no NK cells, B cells or T cells, and this would ... Also, STAT4 is able to activate NK cells (natural killer cells), and STAT5 can drive the formation of white blood cells. In ... In addition, because patients with JAK3 gene mutations have no functional T cells, B cells or NK cells, they would more likely ...
Nest (protein structural motif)
Lee, H-J; Zheng JJ (2010). "PDZ Domains and their binding Partners: Structure Specificity and Modification". Cell Communication ... thereby preventing bacterial cells from multiplying. Nests are defined by the conformation of the main chain atoms, namely the ... in the antibiotic peptide vancomycin which binds a key carboxylate group utilized during the final stages of bacterial cell ...
Cell Communication and Signaling. 16 (1): 12. doi:10.1186/s12964-018-0224-3. PMC 5883603. PMID 29615051. Hornbeck PV, Zhang B, ... CCDC188 has decreased expression in G1 of the cell cycle. Genes with similar mRNA expression in the hypothalamus, supraoptic ... Two phosphate groups have been experimentally verified on serine residues 322 and 324 in B-cell leukemia. CCDC188 is conserved ... Copy number variations of CCDC188 have also been identified in lung squamous cell tumors with 16 tumors having amplifications ...
Tardigrade specific proteins
Cell Communication and Signaling. 18 (1): 178. doi:10.1186/s12964-020-00670-2. PMC 7640644. PMID 33148259. Boothby TC, Tapia H ... It is seen that CAHS proteins are dispersed throughout the cell in normal conditions, but then forms a network of filaments ... They are each named after where the protein is localized within a cell. These proteins are similar to late embryogenesis ... Dried tardigrades have been seen to have an abundance of secretory cells which when rehydrated, are not seen. The mechanism ...
Technopark also hosts a Technology Business Incubation Cell under Kerala Startup Mission. Technopark houses domestic firms, ... "Exports from companies in Technopark: Chapter 21, page:502, section:21.8" (PDF). Information And Communication Technology. ... "Exports from companies in Technopark: Chapter 21, page:220, section:21.66" (PDF). Information And Communication Technology. ...
Mobile positioning data
U. S. Federal Communications Commission (1999). "The Wireless Communications and Public Safety Act (E911)" (PDF). Ahas, R., ... the geographical reference is the location and/or the coverage area of the network cell (initially the ID of the cell). For ... The accuracy of passive mobile positioning is limited to the coverage area of network cells, which can range from a few hundred ... Moreover, the accuracy of passive mobile positioning is limited to the coverage area of network cells, which can range from a ...
Uridine monophosphate synthase
Cell. 122 (6): 957-68. doi:10.1016/j.cell.2005.08.029. hdl:11858/00-001M-0000-0010-8592-0. PMID 16169070. S2CID 8235923. ... Biochemical and Biophysical Research Communications. 390 (2): 337-41. doi:10.1016/j.bbrc.2009.09.128. PMID 19800871. French JB ... Lin T, Suttle DP (May 1995). "UMP synthase activity expressed in deficient hamster cells by separate transferase and ... Somatic Cell Genetics. 9 (3): 359-74. doi:10.1007/BF01539144. PMID 6574608. S2CID 29498380. McClard RW, Black MJ, Livingstone ...
Exposure to loud noises damages the hair cells in the inner ear that are essential for sending neural impulses to the brain in ... nonverbal), the ease of communication, and the noise exposure levels of the worker. Workers may want to wear their hearing aids ... Loss of these hair cells leads to hearing loss that may cause speech and sounds to be muffled or distorted. Tinnitus is often ... Active earmuffs have an electronic component and microphones that allow the user to control their access to communication while ...
Occupation of the Malheur National Wildlife Refuge
... at which point their line of communication was cut. About a week later, David Fry was able to reestablish online communications ... Other cell phone video footage shot by Ryan Bundy, another passenger, also showed Finicum taunting officers and daring them to ... "Ryan Bundy's cell phone video of moments before and after Finicum shooting released". Portland, Oregon: KATU. April 5, 2016. ... Bend, Oregon: Western Communications. Retrieved June 14, 2016. Purdy, Jedediah (January 5, 2016). "The Bundys and the Irony of ...
Cell phones are also very common among all three groups today. Text messaging has made cell phones particularly useful for ... As the world evolves more, however, and technology is used more and more for work and communication, many Hutterite young ...
Development of the reproductive system
Development proceeds and the oogonia become fully surrounded by a layer of connective tissue cells (pre-granulosa cells). In ... it establishes a communication with the exterior. This opening is for a while the primitive urogenital opening, and it extends ... At about the fifth or sixth month the lumen of the vagina is produced by the breaking down of the central cells of the ... For a time the vagina is represented by a solid rod of epithelial cells. A ring-like outgrowth of this epithelium occurs at the ...
Mie theory has been used to determine whether scattered light from tissue corresponds to healthy or cancerous cell nuclei using ... Nature Communications 3, no. 1 (6 November 2012): 1171. https://doi.org/10.1038/ncomms2167. Rahimzadegan, Aso, et al. " ... and biological cells and cellular components, a more detailed approach is necessary. The Mie solution is named after its ...
FUT2 fucosyltransferase transfers a fucose sugar to the end of the ABO(H) precursor in gastrointestinal cells and saliva glands ... communication and notification. The guideline also identifies eight high-priority recommendations and suggests several areas in ... Entry into the host cell is achieved by attachment to host receptors, which mediates endocytosis. Positive-stranded RNA virus ...
New World Communications of Tampa, Inc. August 25, 2019. Archived from the original on August 27, 2019. Frank Pallotta (March ... The attraction is an electronic scavenger hunt that has guests using special "Kimmunicators" (in actuality, customized cell ... New World Communications of Tampa, Inc. August 25, 2019. Archived from the original on August 27, 2019. Pedersen, R. A. (2011 ... including communication, imagination, and the visual and culinary arts. Spaceship Earth, an eighteen-story-tall geodesic sphere ...
Rhomboid-related protein 2
Molecular Cell. 11 (6): 1425-34. doi:10.1016/s1097-2765(03)00181-3. PMID 12820957. Urban S, Lee JR, Freeman M (October 2001). " ... Biochemical and Biophysical Research Communications. 317 (1): 244-52. doi:10.1016/j.bbrc.2004.03.039. PMID 15047175. Cheng TL, ... "Quantitative proteomics screen identifies a substrate repertoire of rhomboid protease RHBDL2 in human cells and implicates it ... "Drosophila rhomboid-1 defines a family of putative intramembrane serine proteases". Cell. 107 (2): 173-82. doi:10.1016/s0092- ...
... communications delivered over mass electronic communication networks Digital media, electronic media used to store, transmit, ... objects in which microorganisms or cells can experience growth Media filter, a filter consisting of several different filter ... Media may refer to: Media (communication), tools used to deliver information or data Advertising media, various media, content ... communications delivered via paper or canvas Published media, any media made available to the public Recording medium, devices ...
... from the zooxanthellate jellyfish Cotylorhiza tuberculata modulates gap junction intercellular communication in human cell ... C. tuberculata have been studied due to their specified cytotoxicity in regards to certain breast cancer cells, which is made ... Since a main objective in cancer research is to create treatments that selectively kill malignant cells while leaving healthy ... possible due to the organism's efficient intercellular gap junction communication. While further studies have been proposed to ...
Coronavirus nucleocapsid protein
Coronaviruses manipulate the cell cycle of the host cell through various mechanisms. In several coronaviruses, including SARS- ... Nature Communications. 12 (1): 5553. Bibcode:2021NatCo..12.5553M. doi:10.1038/s41467-021-25796-w. ISSN 2041-1723. PMC 8455558. ... N also has additional functions in manipulating the cell cycle of the host cell. The N protein is highly immunogenic and ... "Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals". Cell. 181 (7 ...
Interruptions and outside communication were forbidden for the duration of the exam. If a candidate died, officials wrapped his ... When he finally enters his cell and, along with the other candidates, stretches his neck to peer out, he is just like the larva ... The facilities provided for the examinee consisted of an isolated room or cell with a makeshift bed, desk, and bench. Each ... examinee was assigned to a cell according to their number. Paper was provided by the examiners and stamped with an official ...
Politicization of science
Bolsen, Toby; Druckman, James N. (2015). "Counteracting the Politicization of Science". Journal of Communication (65): 746. ... accused the administration in July 2007 of political interference and muzzling him on key issues like embryonic stem cell ... reportedly sent a list to the CDC on words that the agency was prohibited from using in its official communications, including ...
... voice communication and sometimes warm water to heat the diving suit from the surface. Some tourist resorts offer a surface- ... and the large amounts of breathing gas necessary for these dive profiles and ready availability of oxygen sensing cells ...
Before retreat, Russian army destroyed infrastructure facilities of the city (communications, water, heat, electricity, TV ... underground cells. The Kherson district leadership of the OUN was headed by Bogdan Bandera (brother of OUN leader Stepan ...
On January 14, 1994 the agreement with TILTS Communications was concluded and SIA Lattelekom established. As a result of ... tablet computers and cell phones. Lattelecom Interactive TV, soon to be known as Helio iTV, is a high-definition television ... Until January 1, 2003 the company held monopoly on fixed voice communication services thereby turning into the leading fixed ... Until relatively recently, Lattelecom had a monopoly rights on fixed-line voice communications in Latvia, which ended on ...
Apoptosis is a cell self-destruct process that removes toxic and/or useless cells during mammalian development and other life ... Biochemical and Biophysical Research Communications. 264 (1): 176-80. doi:10.1006/bbrc.1999.1497. PMID 10527860. Larsen BD, ... The cell diversity is originated by cell differentiation, which has been attributed to the activation of specific transcription ... Despite this gene being present in every cell, this protein is only expressed in different tissues and cell variety such as ...
Items like cell phones, a cup of coffee, and chewing gum are not recommended to bring to an interview, as it can lead to the ... The ability to convey this complexity allows more media-rich forms of communication to better handle uncertainty (like what can ... When given a series of options, individualists tend to choose the task-oriented option that involves direct communication with ... Media richness theory states that more detailed forms of communication will be able to better convey complex information. ...
Azure Communication Services offers an SDK for creating web and mobile communications applications that include SMS, video ... For example, an event hub can be used to track data from cell phones such as coordinating with a GPS in real time. Queues, ... Relays, which provide bi-directional communication. Unlike queues and topics, a relay doesn't store in-flight messages in its ... Topics, which provide one-directional communication using a subscriber pattern. It is similar to a queue, however, each ...
Charleston church shooting
At the jail, his cell-block neighbor was Michael Slager, the former North Charleston police officer charged with murder after ... According to unnamed officials, he was in online communication with other white supremacists, who did not appear to have ... "Charleston portrait project pays tribute to Emanuel 9". Media General Communications Holdings, LLC. WCBD News 2. May 29, 2016. ... improve communications, develop relationships with local law enforcement, and secure and monitor all entrances to and exits ...
The sum data rate of a cell is increased as well because of a better resource utilization. In addition load balancing: p.42 is ... Carrier aggregation is a technique that is used in wireless communication to increase the data rate per user, whereby multiple ... Carrier aggregation is also called Dual Cell in the context of UMTS/HSPA+. Through carrier aggregation (part of the UMTS ... IEEE Transactions on Communications, 66(2), Sep.2017, 808-818. F. Foukalas and T. Tsiftsis, "Energy Efficient Power Allocation ...
Cytogenetics and Cell Genetics. 27 (2-3): 168-75. doi:10.1159/000131478. PMID 6995030. Hirschhorn R, Huie ML, Kasper JS (Oct ... Biochemical and Biophysical Research Communications. 141 (1): 33-8. doi:10.1016/S0006-291X(86)80330-8. PMID 3099781. Usuki F, ... expressed in Chinese hamster ovary cells". The Journal of Biological Chemistry. 265 (18): 10373-82. doi:10.1016/S0021-9258(18) ... "Temporal expression of HIV-1 envelope proteins in baculovirus-infected insect cells: implications for glycosylation and CD4 ...
Meanwhile, a network of cells and committees known as the Viet Cong Infrastructure provided support and extended control into ... Nui Dat's central position offered short lines of communication, was close but not adjacent to the main population centres, and ...
Error correction code
Hamming codes are only suitable for more reliable single-level cell (SLC) NAND. Denser multi-level cell (MLC) NAND may use ... Many communication channels are not memoryless: errors typically occur in bursts rather than independently. If the number of ... In multi-carrier communication systems, interleaving across carriers may be employed to provide frequency diversity, e.g., to ... The idea is to directly use software ECCs in the communications. For instance in the 5G, the software ECCs could be located in ...
CKLF-like MARVEL transmembrane domain-containing 5
The forced over expression of CMTM5-v1 in Huh7 human hepatic cells also inhibited the ability of these cells to grow in a mouse ... Biochemical and Biophysical Research Communications. 387 (1): 139-42. doi:10.1016/j.bbrc.2009.06.148. PMID 19577543. Wu K, Li X ... Cai B, Xiao Y, Li Y, Zheng S (August 2017). "CMTM5 inhibits renal cancer cell growth through inducing cell-cycle arrest and ... the forced overexpression of CMTM5-v1 in cultured DU145 cells (a human prostate cancer cell line) reduces, while the forced ...
Multiple system atrophy
Speech changes mean that alternative communication may be needed, for example, communication aids or word charts.[citation ... Mesenchymal stem cell therapy may delay the progression of neurological deficits in patients with MSA-cerebellar type. Ronald ... Multiple system atrophy can be explained as cell loss and gliosis or a proliferation of astrocytes in damaged areas of the ... Hass EW, Sorrentino ZA, Xia Y, Lloyd GM, Trojanowski JQ, Prokop S, Giasson BI (August 2021). "Disease-, region- and cell type ...
"Bonang by Cell C". People Magazine. "QUEEN B LAUNCHES BMOJI!". Daily Sun. "Bonang Matheba Bio". Buzz South Africa. 9 February ... Outraged by their lack of communication, Bonang resigned from the radio station the next day. In 2008, Matheba made a ... In 2018, Matheba signed an endorsement deal with cellular network Cell C, a deal that saw her partnering with them to also ...
Cell biology | Nature Communications
Read the latest Research articles in Cell biology from Nature Communications ... The cell wall and cytoplasmic MreB polymers are important for bacterial cell shape. However, Spiroplasma cells lack a cell wall ... Here, the authors develop a culture platform that can dynamically mimic the cell-cell and cell-extracellular matrix ... Alveolar cell fate selection and lifelong maintenance of AT2 cells by FGF signaling Here the authors show that FGF signaling ...
Cell Communication: The Inside Story - Scientific American
Small Cell | Federal Communications Commission
Cell Phone Accessories - Telephones & Communication - Homedepot.ca
New insights on cell-to-cell communication-mRNA "zip codes" | NIDDK
Researchers have identified one way that cells determine which microRNAs to release to affect other cells-an insight that has ... including fat cells (adipocytes), liver cells, and other cells, finding that each cell type secreted different miRNAs in their ... New insights on cell-to-cell communication-mRNA "zip codes". Research Update Dec. 22, 2021. ... This knowledge provides important new insights into cell-to-cell communication and could inform the development of therapies ...
Phone, telephone, cell, call, communication, multimedia icon - Free download
Bi-directional Force Communication on Cell-Matrix | BiFCCM Project | Fact Sheet | H2020 | CORDIS | European Commission
Wellfleet Communications Cell Tower | Cape Cod Commission
Wellfleet Communications Cell Tower (TR15011). Physical project files are available for review at the Cape Cod Commission ... Wellfleet Communications Cell Tower, Wellfleet, MA Staff Report - 9/3/2015 Page 1 of 6 STAFF REPORT PROJECT: DRI REVIEW ... TR15011 Wellfleet Cell Twr mod dec 1-29-19 3225 MAIN STREET • P.O. BOX 226 BARNSTABLE, MASSACHUSETTS 02630 (508) 362-3828 • Fax ...
regulation of cell communication - Ontology Browser - Rat Genome Database
regulation of cell communication + Any process that modulates the frequency, rate or extent of cell communication. Cell ... regulation of cell communication by electrical coupling + regulation of cell communication involved in growth plate cartilage ... Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular ... regulation of cell communication (GO:0010646). Annotations: Rat: (3666) Mouse: (3787) Human: (3997) Chinchilla: (3065) Bonobo ...
FlyPhoneDB: An integrated web-based resource for cell-cell communication prediction in Drosophila | bioRxiv
Altogether, FlyPhoneDB is an easy-to-use framework that can be used to predict cell-cell communication between cell types from ... These depict all of the potential cell-cell communication events, with each node representing a unique cell type and each edge ... 2020 dataset (B) Circle plot shows the cell-cell communication for EGFR signaling pathways, providing a summary of cell ... Jin, S., C. F. Guerrero-Juarez, L. Zhang, I. Chang, R. Ramos et al., 2021 Inference and analysis of cell-cell communication ...
Efficient passivated phthalocyanine-quantum dot solar cells - Chemical Communications (RSC Publishing)
The power conversion efficiency of CdSe and CdS quantum dot sensitized solar cells is enhanced by passivation with ... Efficient passivated phthalocyanine-quantum dot solar cells V. M. Blas-Ferrando, J. Ortiz, V. González-Pedro, R. S. Sánchez, I ... The power conversion efficiency of CdSe and CdS quantum dot sensitized solar cells is enhanced by passivation with ...
Photo of Income, Business, Communications, Cell Phone, Money and Laptop Computer
Cell Phone, Money and Laptop Computer , Acclaim Images ... Income, Business, Communications, Cell Phone, Money and Laptop ... cell, cell phone, cellphone, cellular, commerce, communication, communications, computer, computer network, computers, concept ... Photo of Income, Business, Communications, Cell Phone, Money and Laptop Computer. Stock Photograph by Verna Bice Image Number: ... Stock Photo Description: Making money and income, cell phone, cash, laptop comuputer. Signs and symbols of business and success ...
Cancer: Harnessing cell energy for cancer treatment | Nature Communications | Nature Portfolio
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Cellular Abroad: GSM Rentals and Cell Phone Sales for International Cellular Communication
Cancer and Cell Science - Cognizant Communication Corporation
Mobile communication in macro-cell assisted small cell networks - Patent US-10271252-B2 - PubChem
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Challenges and directions in studying cell-cell communication by extracellular vesicles
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IntercellularSickle cell di2022BiologyHuman umbilical vein endothelial cellsProgenitorSignalingMesenchymal stem2019ProteinRenal cell carcSynapsesProteinsEndothelial cell migrationTumorModulatesInteractionCytoskeletonExtracellular matrixPeople with sickleDifferentiationPathways202310.1038NeuronsInteractions2021ApoptosisVitroNerveContentLymphocytesImmuneStemJunctionalRecipient cellsPhoneGeneDevelopmentalNeuralMolecularInsightsGlialResearchersMembraneLymphomaMiRNAsAngiogenesisTissuesVascularLiverTissueFindingsLineageCancerTowersResearchCytoplasmEarliest stagesTumourEpithelial
- Extracellular vesicles (EVs) are increasingly recognized as important mediators of intercellular communication. (izon.com)
- Here, we highlight areas of consensus as well as contentious issues in our understanding of the intracellular and intercellular journey of EVs: from biogenesis, release and dynamics in the extracellular space, to interaction with and uptake by recipient cells. (izon.com)
- Using an in vitro model in which a confluent monolayer of capillary endothelial cells is mechanically wounded, gap junction-mediated intercellular communication has been studied by loading the cells with the fluorescent dye, Lucifer Yellow. (rupress.org)
- Those intercellular channels, which allow cells to exchange molecules and ions, are crucial to the growth of a glioblastoma tumor, researchers found. (bioquicknews.com)
- A Postdoctoral Scholar Employee position is available in the Eom Lab in the Department of Developmental and Cell Biology, the University of California, to study cellular protrusion mediated intercellular communication in stem cells. (uci.edu)
- Details] Effects of 50 Hz magnetic fields on gap junctional intercellular communication in NIH3T3 cells [med. (emf-portal.org)
Sickle cell di10
- He is a consultant for Pfizer related to sickle cell disease. (cdc.gov)
- Lomé - African health ministers today launched a campaign to ramp up awareness, bolster prevention and care to curb the toll of sickle cell disease, one of the most common illnesses in the region but which receives inadequate attention. (who.int)
- More than 66% of the 120 million people affected worldwide by sickle cell disease live in Africa. (who.int)
- Sickle cell disease is an inherited blood disorder that shortens red blood cell survival, causing anaemia-often called sickle cell anaemia. (who.int)
- Poor blood oxygen levels and blood vessel blockages in people with sickle cell disease can cause extreme pain in the back, chest, hands and feet as well as severe bacterial infections. (who.int)
- In the African region, 38 403 deaths from sickle cell disease were recorded in 2019, a 26% increase from 2000. (who.int)
- Many public health facilities across the region lack the services for prevention, early detection and care for sickle cell disease. (who.int)
- The campaign, launched at a side event on enhancing advocacy on sickle cell disease during the Seventy-second World Health Organization (WHO) Regional Committee for Africa-the region's flagship health meeting, aims to shore up political will and engagement as well as financial resources for sickle cell disease prevention and control across the region. (who.int)
- Most African countries do not have the necessary resources to provide comprehensive care for people with sickle cell disease despite the availability of proven cost-effective interventions for prevention, early diagnosis and management of this condition," said Dr Matshidiso Moeti, WHO Regional Director for Africa. (who.int)
- Sickle cell anemia is the most severe form of sickle cell disease , a group of inherited red blood cell disorders causing unusually shaped, hard, and sticky red blood cells. (cdc.gov)
- Research in the fields of cancer and cell biology. (cognizantcommunication.com)
- Nature Reviews Molecular Cell Biology, March. (izon.com)
- Recent advances in tumor biology have revealed that a detailed analysis of the complex interactions of tumor cells with their adjacent microenvironment (tumor stroma) is mandatory in order to understand the various mechanisms involved in tumor growth and the development of metastasis. (biomedcentral.com)
- We are seeking a highly motivated and career-oriented candidate with research expertise in Developmental Biology, Cell Biology, Molecular Genetics, preferably with some experience in confocal imaging. (uci.edu)
- We use systems biology approaches to define changes in ubiquitylation as activation states change, and to identify ubiquitin ligases that regulate immune cell fate. (upenn.edu)
- We combine this information with genetic, cellular and biochemical approaches to define how ubiquitin enzymes regulate immune cell biology. (upenn.edu)
- Our recent work has employed systems biology approaches in which we intrgrated transcriptome, proteome and ubiquitome information to identify Cullin E3 ubiquitin ligases that are particularly active as T cells transition from resting to activated states. (upenn.edu)
- New research from the Cabernard Lab on cell fusion was recently published in Communications Biology . (washington.edu)
- The general phase courses Plant Physiology and Animal Physiology will emphasize integrative themes and basic concepts that are central to the biology of both life forms (e.g. communication within and between different organisms, signals between cells and organs, symbiosis, cooperation and plant-animal interactions). (ru.nl)
- The journal is devoted to the promotion of pharmaceutical sciences and related disciplines (including biotechnology, cell and molecular biology, medical and other life sciences, and related engineering fields). (who.int)
Human umbilical vein endothelial cells2
- In this study, we used a two-dimensional co-culture of human umbilical vein endothelial cells (HUVEC) with human adipose stromal cells (ASC) without exogenous matrix addition to study self-assembled network formation (SNF) by HUVEC. (msu.ru)
- To elucidate whether miRNAs secreted from neoplastic cells transfer into endothelial cells and are functionally active in the recipient cells, we investigated the effect of exosomal miRNAs derived from leukemia cells (K562) on human umbilical vein endothelial cells (HUVECs). (qxmd.com)
- Lung branching requires differentiation of progenitor cells to be coordinated with morphogenetic events. (nature.com)
- The source of both these cells is another cell type called the glial progenitor cell (GPC). (bipolar1blog.com)
- When glial cells from schizophrenic people are turned into pluripotent stem cells and then Glial progenitor cells and injected into brains of neonatal mice, these mice show all the symptoms of schizophrenia, they were more fearful, anxious, anti-social, and had a variety of cognitive deficits. (bipolar1blog.com)
- The 9 members of this family that exist in mammalian cells evolved from a common yeast progenitor known as RSP5. (upenn.edu)
- Discordant congenital Zyka syndrome twins show differential in vitro viral susceptibility of neural progenitor cells. (bvsalud.org)
- The polarization of distinct scaffold-signaling hubs at opposite cell poles constitutes the basis of asymmetric cell division. (nature.com)
- Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. (mcw.edu)
- Here, we generated a high confidence list of L-R pairs for the major fly signaling pathways and developed FlyPhoneDB, a quantification algorithm that calculates interaction scores to predict L-R interactions between cells. (biorxiv.org)
- Quorum sensing is the mechanism bacteria use for cell-to-cell signaling. (ciriscience.org)
- We are interested in mechanisms underlying cellular protrusion-mediated long-distance cell-to-cell signaling in developing zebrafish. (uci.edu)
- Recent findings, including ours, have shown long-thin cellular protrusion-mediated signaling play critical roles in many contexts, including stem cell maintenance, cancer progression, tissue remodeling/patterning, etc. (uci.edu)
- Ndfip1 restricts mTORC1 signaling and glycolysis in regulatory T cells to prevent autoinflammatory disease. (upenn.edu)
- In 2003, Lamartine reclassified the ectodermal dysplasias into the following 4 functional groups based on the underlying pathophysiologic defect: (1) cell-to-cell communication and signaling, (2) adhesion, (3) development, and (4) other. (medscape.com)
- [ 8 ] Other classification systems categorize the ectodermal dysplasias based on defects in cell-cell communication and signaling, adhesion, transcription regulation, or development. (medscape.com)
- These interactions are determined by structural and biochemical properties of the ECM as well as by communication with surrounding non-neoplastic cells such as endothelial cells (ECs, during the process of transendothelial migration), cancer-associated fibroblasts (CAFs), mesenchymal stem cells (MSC), and a variety of different immune cells including lymphocytes and tumor-associated macrophages (TAMs). (biomedcentral.com)
- Only 2 in 5 children 2-9 years used recommended medication that can prevent sickle cell anemia complications in 2019. (cdc.gov)
- Authors show here that genomic deletion of the p38α mitogen activated protein kinase specifically in the B cell lineage leads to diminished plasma cell differentiation via impairment of a transcriptional regulatory program by BLIMP1. (nature.com)
- The receptor-interacting protein (RIPK1) promotes cell death and contributes to nonalcoholic steatohepatitis pathogenesis. (nature.com)
- Induction of wound-associated communication was unaffected by exposure of the cells to the DNA synthesis inhibitor mitomycin C, but was prevented by the protein synthesis inhibitor, cycloheximide. (rupress.org)
- The current research focused on connexin 46, a protein that is an essential component of cancer stem cells. (bioquicknews.com)
- however, they were unable to rule out the possibility that the protein was parted into its amino acid building blocks and then reattached in the destination cell. (azolifesciences.com)
- The scientists also used a unique set of protein tags to prove that these proteins were all being transferred between cells in the majority of cases within exosomes-tiny, membrane-enclosed compartments packed with proteins, similar to suitcases stuffed with clothes. (azolifesciences.com)
- This protein transports a particular hormone into nerve cells in the developing brain. (medlineplus.gov)
- As a result, this protein is unable to transport T3 into nerve cells effectively. (medlineplus.gov)
- To accomplish this, immune cells can increase protein production, modify existing proteins, or change their rate of protein degradation. (upenn.edu)
- Cytoskeleton offers several reagents for live-cell research including fluorescent proteins, cell permeable protein activators and inhibitors, as well as our recent addition of live cell imaging probes. (cytoskeleton.com)
- CNN reports, a study published in Alzheimer's and dementia, the journal of the Alzheimer's Association found exercise boost levels of a protein known to strengthen communication between brain cells via synapses, which are critical, communicating junctions between nerve cells. (ketv.com)
Renal cell carc3
- Welcome to season two of Medscape's InDiscussion series on renal cell carcinoma (RCC). (medscape.com)
- 2021. Sexual Dimorphism in Cancer: Insights from Transcriptional Signatures in Kidney Tissue and Renal Cell Carcinoma. (who.int)
- 2017. Genome-wide association study identifies multiple risk loci for renal cell carcinoma. (who.int)
- The astrocytes help facilitate the communication between neurons at the synapses by regulating the flow of glutamate and potassium, which enable neurons to "fire" when they are communicating with each other. (bipolar1blog.com)
- miRNAs may be retained by their parent cell or released in exosomes-small cellular delivery packages that transfer miRNAs and proteins from one cell to another. (nih.gov)
- Scientists from Scripps Research Institute discovered hundreds of proteins that are constantly transferred throughout the healthy brain in small membrane-enclosed sacs, revealing a novel mode of communication among brain cells. (azolifesciences.com)
- Scripps Research scientists tracked proteins tagged with biotin (black areas of this electron microscopy image) from retinal cells (pictured) to the visual cortex of the brain. (azolifesciences.com)
- For example, research examining Alzheimer's disease discovered that synuclein and tau-two proteins linked to neurodegeneration-could move between brain cells of the Alzheimer-affected animals. (azolifesciences.com)
- Many of the proteins involved have known functions in the brain, such as tau and synuclein, which are seen progressing between cells in Alzheimer's disease. (azolifesciences.com)
- His work within the lab focuses primarily on the cerebral circulation and he typically probes a defined research question by blending theoretical approaches such as computational modeling with experimental techniques that extend from single proteins, to cells, and then to whole tissues. (uwo.ca)
- Immune cells must continually respond to external stimuli, and adjust their levels of key regulatory proteins, to transition between poised and active states. (upenn.edu)
- A mini tour and lecture that will be led by Artist Dolores Bartholomew on plant communication and the important role the cell cytoskeleton plays along with other cell proteins to coordinate growth and development in plants. (sciencecenter.org)
Endothelial cell migration2
- These results suggest that junctional communication may play an important role in wound repair, possibly by coordinating capillary endothelial cell migration. (rupress.org)
- The most salient feature of this study is the exosome, derived from K562 cells with enforced miR-92a expression, did not affect the growth of HUVECs but did enhance endothelial cell migration and tube formation. (qxmd.com)
- The mutual interactions between tumor cells and cellular and non-cellular components (extracellular matrix = ECM) of the tumor microenvironment will eventually lead to a loss of tissue homeostasis and promote tumor development and progression. (biomedcentral.com)
- Thus, interactions of genetically altered tumor cells and the ECM on the one hand and reactive non-neoplastic cells on the other hand essentially control most aspects of tumorigenesis such as epithelial-mesenchymal-transition (EMT), migration, invasion ( i.e. migration through connective tissue), metastasis formation, neovascularisation, apoptosis and chemotherapeutic drug resistance. (biomedcentral.com)
- During each stage, tumor cells have to detach, migrate, invade, adapt and re-attach by involving matrix degrading enzymes and mechanical processes such as cell adhesion, changes of cell fate, cell movements and motility, and the generation of forces. (biomedcentral.com)
- Since these multiple interactions with the tumor stroma determine not only cancer growth and metastasis but may also develop protective effects with respect to the tumor cells' drug sensitivity/resistance, the tumor stroma also has to be considered as a potential therapeutic target. (biomedcentral.com)
- In this mini-review, we refer to two articles which recently appeared in this journal [ 1 , 2 ] describing the major types of tumor stroma interactions (cancer cell with non-neoplastic cells and cancer cell with ECM). (biomedcentral.com)
- Special attention is devoted to the dialogue of tumor cells with TAMs, CAFs, and ECs and the role of transforming growth factor (TGF)-β in the regulation of cancer cell migration and invasion. (biomedcentral.com)
- The rapid spread of a common and deadly brain tumor has been slowed down significantly in a mouse model by cutting off the way some cancer cells communicate, according to a team of researchers that includes University of Florida (UF) Health faculty. (bioquicknews.com)
- Rather than taking what is a very complex tumor microenvironment with lots of different types of cells, T cells, myeloid cells, B cells, tumor cells, endothelial cells, and dozens of cell types and mushing it all together, putting it in a blender, and trying to figure out what it all means, it allows you to pick out individual cells at a time and ask directed questions. (medscape.com)
- We classified patients into groups on the basis of underlying diseases: immunocompetent patients, solid tumor patients, solid organ transplantation recipients, hematopoietic stem cell transplant recipients, hematologic malignancy patients, and patients receiving long-term steroid treatment. (cdc.gov)
- ALCL was recognized in 1985, when tumor cells consistently demonstrated labeling by the monoclonal antibody Ki-1, a marker later shown to recognize the CD30 antigen. (medscape.com)
- Recently, data generated from single cell RNA sequencing (scRNA-seq) have enabled L-R interaction predictions at an unprecedented resolution. (biorxiv.org)
- S ocial & B ehaviour C hange C ommunication C ell (SBCC) uses the most powerful and fundamental human interaction - communication - for positive influence in the social dimensions. (sbccmalda.org)
- [ 7 ] Similarly, in 2001, Priolo and Laganà reclassified the ectodermal dysplasias into 2 main functional groups: (1) defects in developmental regulation/epithelial-mesenchymal interaction and (2) defects in cytoskeleton maintenance and cell stability. (medscape.com)
- Cytoskeleton is excited to introduce the next generation of Spirochrome's live cell imaging probes - the SPY™ probes. (cytoskeleton.com)
- Following the tour and lecture Dolores and former member of the Gallagher lab, undergraduate Amy Goldfischer will show participants how to create "Cytoskeleton Cells" using the Create 3Doodler tool. (sciencecenter.org)
- Importantly, HUVEC start network formation after 14 hours of co-culture with ASC that coincides with synthesis and secretion of extracellular matrix (ECM) by co-culturing cells. (msu.ru)
People with sickle1
- Everyone can help improve care for people with sickle cell anemia by taking steps to address racism and prejudice. (cdc.gov)
- Additionally, we have determined that these adaptors regulate T cell activation, CD4 differentiation and effector function, and Treg cell metabolism and lineage stability. (upenn.edu)
- Extremely low frequency magnetic fields regulate differentiation of regulatory T cells: potential role for ROS-mediated inhibition on AKT [med. (emf-portal.org)
- Cell-cell communication pathways can be inferred from transcriptomic datasets based on ligand-receptor (L-R) expression. (biorxiv.org)
- To demonstrate that FlyPhoneDB can effectively identify active ligands and receptors to uncover cell-cell communication events, we applied FlyPhoneDB to Drosophila scRNA-seq data sets from adult midgut, abdomen, and blood, and demonstrate that FlyPhoneDB can readily identify previously characterized cell-cell communication pathways. (biorxiv.org)
- The use of iPSCs allows us to examine more precisely the differences in cell fates and gene pathways that occur in neural cells from autistic and typical individuals. (bigthink.com)
- Hepatology communications 2023 0 0. (cdc.gov)
- Nature Communications DOI: 10.1038/ncomms15724. (who.int)
- Neurotransmitters are chemicals, which transport signals from one cell to the next, are typically used by neurons to transmit signals throughout the brain. (azolifesciences.com)
- This research shows that schizophrenia may NOT be the result of abnormalities in neurons, but actually abnormalities in cells that support neurons. (bipolar1blog.com)
- Glia are an important family of support cells found in the brain and play a critical role in the development and maintenance of the brain's complex interconnected network of neurons. (bipolar1blog.com)
- These cells out-competed the animal's own native glia, resulting in mice with brains comprised of animal neurons and human GPCs, oligodendrocytes, and astrocytes. (bipolar1blog.com)
- How does disease affect the functions of brain cells such as the communication between neurons or the structural integrity of the neurons? (kcl.ac.uk)
- By treating the cells with an array of growth factors, the scientists were able to drive the hair cells to become nerve cells (or neurons), much like those found in either the cortex or the midbrain region. (bigthink.com)
- Days 21 and 35 of the study showed cells from typical and autistic people differed significantly in a number of ways, proving that the makeup of neurons in the cortex differs in the autistic and typically developing brains. (bigthink.com)
- Additionally, cells directed to develop as midbrain neurons (a brain region that's not implicated in autism dysfunction) showed only negligible differences between typical and autistic individuals. (bigthink.com)
- Cell communication is the process that mediates interactions between a cell and its surroundings. (mcw.edu)
- All of these methods start by generating a single-cell gene expression matrix of ligand-receptor (L-R) pairs that is then used to predict the strength of interactions between cells. (biorxiv.org)
- Cell Phone Services for South Bend, IN 46601 (St. Joseph County) as of December 2021. (wirelessadvisor.com)
- Details] Repetitive exposure to a 60-Hz time-varying magnetic field induces DNA double-strand breaks and apoptosis in human cells [med. (emf-portal.org)
- Details] Millimeter wave induced reversible externalization of phosphatidylserine molecules in cells exposed in vitro [med. (emf-portal.org)
- In vitro studies based on MCF-7 cell proliferation and induction of vitellogenin in primary culture of rainbow trout hepatocytes. (cdc.gov)
- Astrocytes are the brain's principal support cells, while oligodendrocytes are responsible for producing myelin, the fatty tissue that, like the insulation on electrical wires, wraps the axons that connect different nerve cells. (bipolar1blog.com)
- When researchers transplanted human brain cells generated from individuals diagnosed with childhood-onset schizophrenia into mice, the animal's nerve cell networks did not mature properly and the mice exhibited the same anti-social and anxious behaviors seen in people with the disease. (bipolar1blog.com)
- The inability of these cells to do their job, which is to help nerve cells build and maintain healthy and effective communication networks, appears to be a primary contributor to the disease. (bipolar1blog.com)
- During development, astrocytes colonize areas of the brain and establish domains in which these cells help direct and organize the network of connections between nerve cells. (bipolar1blog.com)
- Because T3 is not taken up by nerve cells, excess amounts of this hormone continue to circulate in the bloodstream. (medlineplus.gov)
- The emergence of differences associated with autism in these nerve cells shows that these differences arise very early in life. (bigthink.com)
- Damaged myelin exposes our nerve fiber and disrupts key communication between our nervous system and brain. (medlineplus.gov)
- 1 ], the architecture and composition of the microenvironment in terms of structural and biochemical properties of the ECM (fiber network morphology collagen content, fiber thickness, extent of intrafibrillar cross-links, and the ratio mesh size-diameter of the migrating cell) determines the degree of resistance the moving cell encounters. (biomedcentral.com)
- Accurate and reliable measures of CD4+ T-lymphocytes (CD4+ T-cells) are essential to the assessment of the immune system of human immunodeficiency virus (HIV)-infected persons (1-3). (cdc.gov)
- and the percentage of lymphocytes that are CD4+ T-cells. (cdc.gov)
- The CDC guidelines concerning CD4+ T-cell determinations (33) were first published in the MMWR in 1992 to provide laboratorians with the most complete information about how to measure CD4+ T-lymphocytes in blood from HIV-infected persons by using flow cytometry. (cdc.gov)
- Our focus is on defining new mechanisms that regulate immune cell activation and protective immune responses. (upenn.edu)
- During pathogenic infection, immune cells collaborate to remove invading organisms while minimizing collateral damage. (upenn.edu)
- We are now poised to define how cullin ligases form distinct ubiquitin complexes in T cells or other immune cells, and the unique set of substrates targeted by these complexes. (upenn.edu)
- The research found the cell-based quadrivalent influenza vaccine (QIVc) produced a sufficient immune response in children aged two to 18 years. (edu.au)
- MS is considered to be an autoimmune disease, in which your immune system mistakenly attacks healthy cells in your body. (medlineplus.gov)
- As we review here, the experimental accessibility of these epidermal lineages, particularly in Arabidopsis , has made stomata a conceptual and technical framework for the study of cell fate, stem cells, and cell polarity in plants. (biologists.com)
- Researchers focused on disrupting the cell-to-cell communication that allows cancer stem cells to spread. (bioquicknews.com)
- In the new study, the researchers obtained skin cells from individuals with childhood-onset schizophrenia and reprogrammed the cells to create induced pluripotent stem cells (iPSC) which, like embryonic stem cells, are capable of giving rise to any cell type found in the body. (bipolar1blog.com)
- Mortality rates were highest in hematopoietic stem cell transplantation recipients (22% at 30 days). (cdc.gov)
- HMPV infection progresses from upper respiratory tract infection (URI) to lower respiratory tract disease in up to 60% of hematopoietic stem cell transplant (HCT) recipients ( 14 ), and mortality rates are 6%-40% ( 15 , 16 ). (cdc.gov)
- The study used induced pluripotent stem cells to recreate the development of each sample in the womb. (bigthink.com)
- These induced pluripotent stem cells (referred to as IPSCs) retain the genetic identity of the person from which they came, and the cells restart their development as it would have happened in the womb. (bigthink.com)
- For nearly 20 years, dental stem cells (DSCs) have been successfully isolated from mature/immature teeth and surrounding tissue, including dental pulp of permanent teeth and exfoliated deciduous teeth, periodontal ligaments, dental follicles, and gingival and apical papilla. (bvsalud.org)
- Adipose-derived stem cell (ADSC) is a promising cell type for cultured meat. (bvsalud.org)
- Junctional communication is induced in migrating capillary endothelial cells. (rupress.org)
- This redirection of miRNAs led to changes in gene activity in the recipient cells, suggesting that altering these sequence motifs to change the location of miRNAs could be used to affect downstream cellular activity. (nih.gov)
- If the cell phone can's connect, then amateur VHF and UHF probably wouldn't work either, so you'd have to rely upon HF with longer range but much greater variability in terms of signal propagation. (stanford.edu)
- The SureCall Fusion5s™ cell phone signal booster increases voice, text and 4G LTE signal strength for all North American cell carriers, including AT&T, Verizon, Sprint and T-Mobile. (nielsoncom.com)
- In a cell phone. (cookerly.com)
- Today when you meet someone and exchange phone numbers, there's a very good chance that the only time you will ever enter that person's number on your keypad is when you are adding it to the "New Contact" entry you created on your cell phone. (cookerly.com)
- Ever wanted to build a telephone TAP to intercept cell phone communications? (cognyl-fournier.com)
- Paget had his jammer and an amplifier on stage but declined to turn them on saying they would "probably knock out all Las Vegas cell phone systems. (cognyl-fournier.com)
- On the other hand, the future communication network will be secretly controlled by mobile cell phone jammer . (perfectjammer.com)
- Cell phone ringing interferes with watching movies, causing discomfort. (perfectjammer.com)
- It will use Cell Phone Disruptor Kit Amazon to interfere with cell phone communication. (perfectjammer.com)
- BT8 18W GPS WiFi Cell Phone 3G 4G Jammer. (perfectjammer.com)
- This 8 bands desktop cell phone jammer has a jamming distance of 50 meters. (perfectjammer.com)
- Is it actual communication systems like phone lines and cell towers? (cdc.gov)
- The cell phone companies listed below are licensed to provide ZIP code 46601 in South Bend, IN (St. Joseph County) with wireless phone services. (wirelessadvisor.com)
- Find and research all the cell phone companies serving your area. (wirelessadvisor.com)
- BURNABY, BC, March 22, 2013 /CNW/ - Matt Buie , a Financial Planner and father living in Burnaby, BC, was recently stunned by a $22,000 roaming charge on his cell phone account incurred by his 11-year-old while on vacation. (newswire.ca)
- After Buie spoke out in the media and talked to other cell phone users he quickly realized that he was not alone in feeling price-gouged, and is now taking action. (newswire.ca)
- Solar flares can trip electrical power grids and disrupt satellites including GPS as well as other radio communication systems including cell phone networks. (pocketgpsworld.com)
- In males (who have only one X chromosome), one altered copy of the gene in each cell is sufficient to cause the condition. (medlineplus.gov)
- In X-linked recessive inheritance, a female with one altered copy of the gene in each cell is called a carrier . (medlineplus.gov)
- Details] Phosphorylation and gene expression of p53 are not affected in human cells exposed to 2.1425 GHz band CW or W-CDMA modulated radiation allocated to mobile radio base stations [med. (emf-portal.org)
- Multicellular organisms rely on cell-cell communication to exchange information necessary for developmental processes and metabolic homeostasis. (biorxiv.org)
- Single cell RNA sequencing (scRNA-seq) is increasingly being used for high-throughput and high-precision studies to characterize cell states and cell types, and in particular is quickly becoming the method of choice to study developmental and physiological processes. (biorxiv.org)
- The plant stomatal lineage manifests features common to many developmental contexts: precursor cells are chosen from an initially equivalent field of cells, undergo asymmetric and self-renewing divisions, communicate among themselves and respond to information from a distance. (biologists.com)
- Developmental models distill essential problems faced by cells, tissues and organisms into simplified and experimentally accessible systems. (biologists.com)
- Cells from autistic people formed smaller rosettes (or did not form any rosettes at all), and key developmental genes were expressed at lower levels. (bigthink.com)
- Hormones also distribute through the brain, influencing cell growth and aiding in the formation of new neural connections. (azolifesciences.com)
- Please follow us on social media to learn of the latest publications and news in Molecular Plant and Plant Communications ! (kxgw100.com)
- This knowledge provides important new insights into cell-to-cell communication and could inform the development of therapies for diseases associated with miRNA dysfunction. (nih.gov)
- These cells are Glial cells or Glia. (bipolar1blog.com)
- While mice who were implanted with glial cells that were from normal people did not show these symptoms. (bipolar1blog.com)
- The findings of this study argue that glial cell dysfunction may be the basis of childhood-onset schizophrenia," said University of Rochester Medical Center (URMC) neurologist Steve Goldman, M.D., Ph.D., co-director of the Center for Translational Neuromedicine and lead author of the study which appears today in the journal Cell . (bipolar1blog.com)
- Researchers have identified short genetic sequences on microRNAs (miRNAs) that help determine which miRNAs are retained by the cell that produced them and which are released to affect other cells. (nih.gov)
- Eight UF Health researchers took part in the study, which was co-authored by Dr. Deleyrolle and published in an open-access article in the May 19, 2015 issue of Cell Reports. (bioquicknews.com)
- This active group of researchers and clinicians in London hold expertise in diseases associated with aging of cells of the brain, vasculature or heart. (uwo.ca)
- Researchers at Nanyang Technological University, Singapore (NTU Singapore) have developed a quantum communication chip that is 1,000 times smaller than current quantum setups, but offers the. (innovationtoronto.com)
- At various stages, the researchers examined the developing cells' appearance and sequenced their RNA to see which genes the cells were expressing. (bigthink.com)
- Healing and death begin on the cell membrane so that means when you learn how to heal the cell you will get well. (quantumwellness.rs)
- Anaplastic large cell lymphomas (ALCLs) are distinguished from other lymphomas by their anaplastic cytology and constant membrane expression of the CD30 antigen (an activation marker for B or T cells). (medscape.com)
- IMSEAR at SEARO: Mast cell reactivity in lymphoma: a preliminary communication. (who.int)
- Sharma VK, Agrawal A, Pratap VK, Nagar AM, Mehrotra ML. Mast cell reactivity in lymphoma: a preliminary communication. (who.int)
- Fifty nodes of Hodgkin's disease, 50 of non-Hodgkin's lymphoma and 20 of reactive hyperplasia revealed varying degree of mast cell reactivity. (who.int)
- The number of mast cells was more in nodular sclerosis variety of Hodgkin's disease than other Rye-subtypes, and more in Hodgkin's group than non-Hodgkin's, out of the latter, the diffuse histiocytic lymphoma revealed higher number. (who.int)
- This ulcerated nodule of localized primary cutaneous CD30+ anaplastic large cell lymphoma is relatively nonspecific in appearance. (medscape.com)
- However, the mechanisms by which cells determine which miRNAs go where are not understood. (nih.gov)
- To address this gap in knowledge, scientists examined miRNAs in exosomes secreted by different types of mouse cells grown in the laboratory, including fat cells (adipocytes), liver cells, and other cells, finding that each cell type secreted different miRNAs in their exosomes. (nih.gov)
- Additionally, some miRNAs were more likely to be found in exosomes, while others were mostly retained by the cell that produced them, suggesting a mechanism of miRNA sorting. (nih.gov)
- To understand how the sorting occurred, the scientists studied whether specific genetic sequences in miRNAs determined whether they were packaged into exosomes or retained by cells-was there a "zip code" telling the cell where miRNAs should go? (nih.gov)
- These results provide new understanding about how cells sort miRNAs and communicate with one another. (nih.gov)
- Secreted miRNAs enclosed in exosomes also have an important role in cell-cell communication. (qxmd.com)
- Our results support the idea that exosomal miRNAs have an important role in neoplasia-to-endothelial cell communication. (qxmd.com)
- Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs. (qxmd.com)
- MicroRNAs (miRNAs) are a class of short non-coding RNA that play important roles in disease processes in animals and are present in a highly stable cell-free form in body fluids. (cdc.gov)
- Urokinase system is an important participant in the communication between endothelial and mesenchymal cells during angiogenesis. (msu.ru)
- Cardiomyocytes mediate anti-angiogenesis in type 2 diabetic rats through the exosomal transfer of miR-320 into endothelial cells. (qxmd.com)
- Exosomal miR-135b shed from hypoxic multiple myeloma cells enhances angiogenesis by targeting factor-inhibiting HIF-1. (qxmd.com)
- With what he called an "integrated biofabrication platform," Modern Meadow CEO Andras Forgacs said his company engineers animal cells and tissues to produce edible meat products and material goods like leather. (agri-pulse.com)
- and 2) cell-cell communication in vascular tissue. (uwo.ca)
- Humoral and T-cell-mediated immunity to SARS-CoV-2 vaccination in patients with liver disease and transplant recipients. (cdc.gov)
- To produce a hide, the Modern Meadow platform uses the best naturally performing cells of a cow, then proceeds to "tweak the performance of cells so they grow faster," and then focuses on tissue architecture. (agri-pulse.com)
- These findings, published in Nature Communications this week, may provide another strategy for treating cancer. (natureasia.com)
- These findings may result in new strategies for delivering chemotherapeutics to cancer cells. (natureasia.com)
- The findings, published in The New England Journal of Medicine , were the first on the absolute efficacy of a cell-based influenza vaccine in children as young as two years of age. (edu.au)
- Stomata (the epidermal valves that mediate gas exchange between plants and the atmosphere) and the lineage from which they are derived have emerged as a pre-eminent model for answering questions about cell fate and pattern in plants. (biologists.com)
- A drug carrier that uses the 'energy molecule' inside a cancer cell to trigger release of drugs at the tumour site is reported to be successful in treating cancer in mice. (natureasia.com)
- Cancer cells often have high levels of ATP that provides energy for metabolism and this could be exploited for treatment. (natureasia.com)
- They find that this approach enhanced doxorubicin-induced cancer cell death in the laboratory in cultured cells and in mice. (natureasia.com)
- To do that, they targeted a channel that cancer cells use to transfer molecules. (bioquicknews.com)
- miR-92a inhibits peritoneal dissemination of ovarian cancer cells by inhibiting integrin α5 expression. (qxmd.com)
- Effect of 10.5 GHz CW radiofrequency radiation exposure on normal and prostate cancer cell morphology [med. (emf-portal.org)
- Brendan Cotter, a senior vice president for Blackboard, said cell broadcasting lets the company indentify a specific area and send a mass emergency notification through single or multiple towers and have them received via text message to anyone in that geo-targeted area. (urgentcomm.com)
- The tag was implanted in the retinal ganglion cells of rats' eyes by the research team. (azolifesciences.com)
- Research consistently shows evidence-based communication programmes can increase knowledge, shift attitudes and cultural norms and produce changes in a wide variety of behaviours. (sbccmalda.org)
- Our research looks at the similarities and differences between these diseases to find the keys to slow or halt loss of brain cells at the earliest stages. (kcl.ac.uk)
- The research was funded by UK-based Seqirus , which announced last year plans to build a cell-based manufacturing facility in Australia, which will be the first facility of its kind in the Southern Hemisphere. (edu.au)
- He also served as the Director of Extramural Research at the National Institute on Deafness and Other Communication Disorders (NIDCD), part of the National Institutes of Health (NIH), from 1999-2002. (aro.org)
- It seeks to foster multi-disciplinary research and collaboration among scientists, pharmaceutical industries and healthcare sector as well as provide an international forum for the communication and evaluation of data, methods and opinions in pharmaceutical sciences and related disciplines. (who.int)
- Cy3-miR-92a derived from K562 cells was detected in the cytoplasm of HUVECs, and the Cy3-miR-92a co-localized with the signals of an exosomal marker, CD63. (qxmd.com)
- Histologically, ALCL is characterized by sheets of large pleomorphic cells with abundant cytoplasm, horseshoe- or wreath-shaped nuclei, and multiple prominent nucleoli. (medscape.com)
- A new study shows that the atypical development of autism in human brain cells starts at the very earliest stages of brain organization, which can happen as early as the third week of pregnancy. (bigthink.com)
- Nanoparticles can deliver drugs to tumours but improvements in selectively targeting tumour cells are required. (natureasia.com)
- Viral NA b inhibition prevents sialic acid cleavage from HA beta virus gets trapped inside cells, and epithelial spread is blocked. (medscape.com)
- These drugs trap the virus inside the infected respiratory epithelial cells and prevent spread to other cells. (medscape.com)