Cell Biology
Biology
Systems Biology
Molecular Biology
Developmental Biology
Cells
Computational Biology
A field of biology concerned with the development of techniques for the collection and manipulation of biological data, and the use of such data to make biological discoveries or predictions. This field encompasses all computational methods and theories for solving biological problems including manipulation of models and datasets.
Synthetic Biology
Stem Cells
Models, Biological
Signal Transduction
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
Cell Differentiation
Regenerative Medicine
Planarians
Neoplasms
Gene Expression Profiling
Cell Lineage
Biochemistry
Embryonic Stem Cells
Stem Cell Transplantation
The transfer of STEM CELLS from one individual to another within the same species (TRANSPLANTATION, HOMOLOGOUS) or between species (XENOTRANSPLANTATION), or transfer within the same individual (TRANSPLANTATION, AUTOLOGOUS). The source and location of the stem cells determines their potency or pluripotency to differentiate into various cell types.
Neoplastic Stem Cells
Microscopy, Fluorescence
Cells, Cultured
Allergy and Immunology
Organelles
Research
Critical and exhaustive investigation or experimentation, having for its aim the discovery of new facts and their correct interpretation, the revision of accepted conclusions, theories, or laws in the light of newly discovered facts, or the practical application of such new or revised conclusions, theories, or laws. (Webster, 3d ed)
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Gene Expression Regulation
Proteins
Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.
Phenotype
Microscopy
The use of instrumentation and techniques for visualizing material and details that cannot be seen by the unaided eye. It is usually done by enlarging images, transmitted by light or electron beams, with optical or magnetic lenses that magnify the entire image field. With scanning microscopy, images are generated by collecting output from the specimen in a point-by-point fashion, on a magnified scale, as it is scanned by a narrow beam of light or electrons, a laser, a conductive probe, or a topographical probe.
Neurobiology
Software
Gene Regulatory Networks
Interacting DNA-encoded regulatory subsystems in the GENOME that coordinate input from activator and repressor TRANSCRIPTION FACTORS during development, cell differentiation, or in response to environmental cues. The networks function to ultimately specify expression of particular sets of GENES for specific conditions, times, or locations.
Green Fluorescent Proteins
Cell Movement
Bioengineering
Microfluidic Analytical Techniques
Protein Transport
Stem Cell Niche
Tissue Engineering
Mutation
Cytoskeleton
Cleome
Embryology
Biological Evolution
Biotechnology
Body of knowledge related to the use of organisms, cells or cell-derived constituents for the purpose of developing products which are technically, scientifically and clinically useful. Alteration of biologic function at the molecular level (i.e., GENETIC ENGINEERING) is a central focus; laboratory methods used include TRANSFECTION and CLONING technologies, sequence and structure analysis algorithms, computer databases, and gene and protein structure function analysis and prediction.
Disease
Bioartificial Organs
Oligonucleotide Array Sequence Analysis
Nanotechnology
Epithelial Cells
Cells that line the inner and outer surfaces of the body by forming cellular layers (EPITHELIUM) or masses. Epithelial cells lining the SKIN; the MOUTH; the NOSE; and the ANAL CANAL derive from ectoderm; those lining the RESPIRATORY SYSTEM and the DIGESTIVE SYSTEM derive from endoderm; others (CARDIOVASCULAR SYSTEM and LYMPHATIC SYSTEM) derive from mesoderm. Epithelial cells can be classified mainly by cell shape and function into squamous, glandular and transitional epithelial cells.
Genetic Engineering
Nuclear Reprogramming
The process that reverts CELL NUCLEI of fully differentiated somatic cells to a pluripotent or totipotent state. This process can be achieved to a certain extent by NUCLEAR TRANSFER TECHNIQUES, such as fusing somatic cell nuclei with enucleated pluripotent embryonic stem cells or enucleated totipotent oocytes. GENE EXPRESSION PROFILING of the fused hybrid cells is used to determine the degree of reprogramming. Dramatic results of nuclear reprogramming include the generation of cloned mammals, such as Dolly the sheep in 1997.
Mammals
Serial Publications
Cell Division
Computer Simulation
Cell Dedifferentiation
Metabolic Networks and Pathways
Algorithms
Universities
Genome
Models, Animal
Amino Acid Sequence
Cell Cycle
The complex series of phenomena, occurring between the end of one CELL DIVISION and the end of the next, by which cellular material is duplicated and then divided between two daughter cells. The cell cycle includes INTERPHASE, which includes G0 PHASE; G1 PHASE; S PHASE; and G2 PHASE, and CELL DIVISION PHASE.
Microtechnology
Manufacturing technology for making microscopic devices in the micrometer range (typically 1-100 micrometers), such as integrated circuits or MEMS. The process usually involves replication and parallel fabrication of hundreds or millions of identical structures using various thin film deposition techniques and carried out in environmentally-controlled clean rooms.
Evolution, Molecular
Gene Expression Regulation, Developmental
Membrane Proteins
Transcription Factors
Microfluidics
Plants
Multicellular, eukaryotic life forms of kingdom Plantae (sensu lato), comprising the VIRIDIPLANTAE; RHODOPHYTA; and GLAUCOPHYTA; all of which acquired chloroplasts by direct endosymbiosis of CYANOBACTERIA. They are characterized by a mainly photosynthetic mode of nutrition; essentially unlimited growth at localized regions of cell divisions (MERISTEMS); cellulose within cells providing rigidity; the absence of organs of locomotion; absence of nervous and sensory systems; and an alternation of haploid and diploid generations.
Extracellular Matrix
MicroRNAs
Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer, that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC) of target RNA by binding to homologous 3'UTR region as an imperfect match. The small temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered, and are from a class of miRNAs involved in developmental timing.
Microscopy, Confocal
Biomedical Research
RNA Interference
A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-INDUCED SILENCING COMPLEX. DNA METHYLATION may also be triggered during this process.
Luminescent Proteins
Models, Molecular
RNA, Messenger
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Cell Membrane
Epigenesis, Genetic
A genetic process by which the adult organism is realized via mechanisms that lead to the restriction in the possible fates of cells, eventually leading to their differentiated state. Mechanisms involved cause heritable changes to cells without changes to DNA sequence such as DNA METHYLATION; HISTONE modification; DNA REPLICATION TIMING; NUCLEOSOME positioning; and heterochromatization which result in selective gene expression or repression.
Gene Expression
Cell Communication
Autobiography as Topic
Time-Lapse Imaging
Cellular Microenvironment
Dimethylpolysiloxanes
Silicone polymers which consist of silicon atoms substituted with methyl groups and linked by oxygen atoms. They comprise a series of biocompatible materials used as liquids, gels or solids; as film for artificial membranes, gels for implants, and liquids for drug vehicles; and as antifoaming agents.
Cell Transplantation
Apoptosis
One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.
Cell Survival
Drosophila
Base Sequence
Protein Binding
Drug Design
The molecular designing of drugs for specific purposes (such as DNA-binding, enzyme inhibition, anti-cancer efficacy, etc.) based on knowledge of molecular properties such as activity of functional groups, molecular geometry, and electronic structure, and also on information cataloged on analogous molecules. Drug design is generally computer-assisted molecular modeling and does not include pharmacokinetics, dosage analysis, or drug administration analysis.
Neurons
Flow Cytometry
Technique using an instrument system for making, processing, and displaying one or more measurements on individual cells obtained from a cell suspension. Cells are usually stained with one or more fluorescent dyes specific to cell components of interest, e.g., DNA, and fluorescence of each cell is measured as it rapidly transverses the excitation beam (laser or mercury arc lamp). Fluorescence provides a quantitative measure of various biochemical and biophysical properties of the cell, as well as a basis for cell sorting. Other measurable optical parameters include light absorption and light scattering, the latter being applicable to the measurement of cell size, shape, density, granularity, and stain uptake.
Fluorescent Dyes
High-Throughput Screening Assays
Internet
Eukaryotic Cells
Disease Models, Animal
Single-Cell Analysis
Immunohistochemistry
Host-Pathogen Interactions
Mice, Transgenic
Induced Pluripotent Stem Cells
Educational Measurement
Neural Stem Cells
Homeostasis
Models, Genetic
Protein Structure, Tertiary
The level of protein structure in which combinations of secondary protein structures (alpha helices, beta sheets, loop regions, and motifs) pack together to form folded shapes called domains. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure. Small proteins usually consist of only one domain but larger proteins may contain a number of domains connected by segments of polypeptide chain which lack regular secondary structure.
Morphogenesis
Cell Polarity
Transcription, Genetic
Drosophila Proteins
Translational Medical Research
Molecular Imaging
Fluorescence
Saccharomyces cerevisiae
Drosophila melanogaster
Actins
Filamentous proteins that are the main constituent of the thin filaments of muscle fibers. The filaments (known also as filamentous or F-actin) can be dissociated into their globular subunits; each subunit is composed of a single polypeptide 375 amino acids long. This is known as globular or G-actin. In conjunction with MYOSINS, actin is responsible for the contraction and relaxation of muscle.
Reverse Transcriptase Polymerase Chain Reaction
Endocytosis
Biological Markers
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
Gene Expression Regulation, Neoplastic
Microscopy, Interference
The science and application of a double-beam transmission interference microscope in which the illuminating light beam is split into two paths. One beam passes through the specimen while the other beam reflects off a reference mirror before joining and interfering with the other. The observed optical path difference between the two beams can be measured and used to discriminate minute differences in thickness and refraction of non-stained transparent specimens, such as living cells in culture.
Cell Nucleus
Within a eukaryotic cell, a membrane-limited body which contains chromosomes and one or more nucleoli (CELL NUCLEOLUS). The nuclear membrane consists of a double unit-type membrane which is perforated by a number of pores; the outermost membrane is continuous with the ENDOPLASMIC RETICULUM. A cell may contain more than one nucleus. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)
Viruses
Mitosis
Satellite Cells, Skeletal Muscle
Genetic Techniques
Species Specificity
The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.
Zebrafish
Biological Transport
Biocompatible Materials
Mass Spectrometry
Sequence Analysis, DNA
Hair Follicle
A tube-like invagination of the EPIDERMIS from which the hair shaft develops and into which SEBACEOUS GLANDS open. The hair follicle is lined by a cellular inner and outer root sheath of epidermal origin and is invested with a fibrous sheath derived from the dermis. (Stedman, 26th ed) Follicles of very long hairs extend into the subcutaneous layer of tissue under the SKIN.
Caenorhabditis elegans
Biosensing Techniques
Cell Transformation, Neoplastic
Endothelial Cells
Highly specialized EPITHELIAL CELLS that line the HEART; BLOOD VESSELS; and lymph vessels, forming the ENDOTHELIUM. They are polygonal in shape and joined together by TIGHT JUNCTIONS. The tight junctions allow for variable permeability to specific macromolecules that are transported across the endothelial layer.
Mice, Knockout
Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.
RNA, Small Interfering
Small double-stranded, non-protein coding RNAs (21-31 nucleotides) involved in GENE SILENCING functions, especially RNA INTERFERENCE (RNAi). Endogenously, siRNAs are generated from dsRNAs (RNA, DOUBLE-STRANDED) by the same ribonuclease, Dicer, that generates miRNAs (MICRORNAS). The perfect match of the siRNAs' antisense strand to their target RNAs mediates RNAi by siRNA-guided RNA cleavage. siRNAs fall into different classes including trans-acting siRNA (tasiRNA), repeat-associated RNA (rasiRNA), small-scan RNA (scnRNA), and Piwi protein-interacting RNA (piRNA) and have different specific gene silencing functions.
Physics
Bacteria
One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.
Eukaryota
One of the three domains of life (the others being BACTERIA and ARCHAEA), also called Eukarya. These are organisms whose cells are enclosed in membranes and possess a nucleus. They comprise almost all multicellular and many unicellular organisms, and are traditionally divided into groups (sometimes called kingdoms) including ANIMALS; PLANTS; FUNGI; and various algae and other taxa that were previously part of the old kingdom Protista.
Models, Theoretical
Embryo, Nonmammalian
Neurodegenerative Diseases
Feedback, Physiological
Gametogenesis
Fungi
A kingdom of eukaryotic, heterotrophic organisms that live parasitically as saprobes, including MUSHROOMS; YEASTS; smuts, molds, etc. They reproduce either sexually or asexually, and have life cycles that range from simple to complex. Filamentous fungi, commonly known as molds, refer to those that grow as multicellular colonies.
Image Processing, Computer-Assisted
How cells (might) sense microgravity. (1/414)
This article is a summary of a lecture presented at an ESA/NASA Workshop on Cell and Molecular Biology Research in Space that convened in Leuven, Belgium, in June 1998. Recent studies are reviewed which suggest that cells may sense mechanical stresses, including those due to gravity, through changes in the balance of forces that are transmitted across transmembrane adhesion receptors that link the cytoskeleton to the extracellular matrix and to other cells (e.g., integrins, cadherins, selectins). The mechanism by which these mechanical signals are transduced and converted into a biochemical response appears to be based, in part, on the finding that living cells use a tension-dependent form of architecture, known as tensegrity, to organize and stabilize their cytoskeleton. Because of tensegrity, the cellular response to stress differs depending on the level of pre-stress (pre-existing tension) in the cytoskeleton and it involves all three cytoskeletal filament systems as well as nuclear scaffolds. Recent studies confirm that alterations in the cellular force balance can influence intracellular biochemistry within focal adhesion complexes that form at the site of integrin binding as well as gene expression in the nucleus. These results suggest that gravity sensation may not result from direct activation of any single gravioreceptor molecule. Instead, gravitational forces may be experienced by individual cells in the living organism as a result of stress-dependent changes in cell, tissue, or organ structure that, in turn, alter extracellular matrix mechanics, cell shape, cytoskeletal organization, or internal pre-stress in the cell-tissue matrix.--Ingber, D. How cells (might) sense microgravity. (+info)Mapping the literature of cytotechnology. (2/414)
The major purpose of this study was to identify and assess indexing coverage of core journals in cytotechnology. It was part of a larger project sponsored by the Nursing and Allied Health Resources Section of the Medical Library Association to map the literature of allied health. Three representative journals in cytotechnology were selected and subjected to citation analysis to determine what journals, other publication types, and years were cited and how often. Bradford's Law of Scattering was applied to the resulting list of cited journals to identify core titles in the discipline, and five indexes were searched to assess coverage of these core titles. Results indicated that the cytotechnology journal literature had a small core but wide dispersion: one third of the 21,021 journal citations appeared in only 3 titles; another third appeared in an additional 26 titles; the remaining third were scattered in 1,069 different titles. Science Citation Index Expanded rated highest in indexing coverage of the core titles, followed by MEDLINE, EMBASE/Excerpta Medica, HealthSTAR, and Cumulative Index to Nursing and Allied Health Literature (CINAHL). The study's results also showed that journals were the predominantly cited format and that citing authors relied strongly on more recent literature. (+info)Antibodies and sperm survival in the female tract of the mouse and rabbit. (3/414)
Rabbit and mouse spermatozoa from male and female tracts have been examined for their species-antigenic surface character, and for adherent antibodies, by double immunofluorescence techniques. Mouse spermatozoa from the ductus deferens showed an area over the acrosome which was positive to anti-mouse serum that had been absorbed with some male mouse somatic tissues including blood, but those from the uterus and oviduct were not stained. Spermatozoa from the uterus were shown to have an antibody coat on the acrosome, with anti-mouse IgG, but those from the ductus deferens and oviduct did not. Rabbit spermatozoa were more variable but their activity was similar: ejaculated spermatozoa sometimes already had antibody of male origin; the majority of the spermatozoa arriving early in the uterus were coated, but in general those that attained the oviducts were not coated. The results are interpreted as evidence for selection by the female tract of a small antigenically different population; the majority of spermatozoa are rejected and/or destroyed. (+info)A new miniature hydrostatic pressure chamber for microscopy. Strain-free optical glass windows facilitate phase-contrast and polarized-light microscopy of living cells. Optional fixture permits simultaneous control of pressure and temperature. (4/414)
This paper describes the development of a miniature, temperature-controlled, stainless steel pressure chamber which uses strain-free optical glass for windows. It is directly adaptable to standard phase-contrast and polarized-light microscopes and requires a minimum amount of equipment to generate and measure pressure. Birefringence retardation (BR) og 0.1 nm up to 3,000 psi, 0.4 nm up to 5,000 psi and 1.0 nm up to 10,000 psi can be detected over a 0.75-mm central field with two strain-free Leitz 20 times UM objectives, one used as a condenser. In phase-contrast studies a Nikon DML 40 times phase objective and Zeiss model IS long working-distance phase condenser were used, with little deterioration of image quality or contrast at pressures as high as 12,000 psi. The actual design process required a synthesis of various criteria which may be categorized under four main areas of consideration: (a) specimen physiology; (b) constraints imposed by available optical equipment and standard microscope systems; (c) mechanical strength and methods for generating pressure; and (d) optical requirements of the chamber windows. Procedures for using the chambers, as well as methods for shifting and controlling the temperature within the chamber, are included. (+info)Prototype Web-based continuing medical education using FlashPix images. (5/414)
Continuing Medical Education (CME) is a requirement among practicing physicians to promote continuous enhancement of clinical knowledge to reflect new developments in medical care. Previous research has harnessed the Web to disseminate complete pathology CME case studies including history, images, diagnoses, and discussions to the medical community. Users submit real-time diagnoses and receive instantaneous feedback, eliminating the need for hard copies of case material and case evaluation forms. This project extends the Web-based CME paradigm with the incorporation of multi-resolution FlashPix images and an intuitive, interactive user interface. The FlashPix file format combines a high-resolution version of an image with a hierarchy of several lower resolution copies, providing real-time magnification via a single image file. The Web interface was designed specifically to simulate microscopic analysis, using the latest Javascript, Java and Common Gateway Interface tools. As the project progresses to the evaluation stage, it is hoped that this active learning format will provide a practical and efficacious environment for continuing medical education with additional application potential in classroom demonstrations, proficiency testing, and telepathology. Using Microsoft Internet Explorer 4.0 and above, the working prototype Web-based CME environment is accessible at http://telepathology.upmc.edu/WebInterface/NewInterface/welcome.html. (+info)A brief history of the Japan Society for Cell Biology. (6/414)
The Japan Society for Cell Biology (JSCB) was first founded in 1950 as the Japan Society for Cellular Chemistry under the vigorous leadership of Seizo Katsunuma, in collaboration with Shigeyasu Amano and Satimaru Seno. The Society was provisionally named as above simply because cell biology had not yet been coined at that time in Japan, although in prospect and reality the Society was in fact for the purpose of pursuing cell biology. Later in 1964, the Society was properly renamed as the Japan Society for Cell Biology. After this renaming, the JSCB made great efforts to adapt itself to the rapid progress being made in cell biology. For this purpose the Society's constitution was created in 1966 and revised in 1969. According to the revised constitution, the President, Executive Committee and Councils were to be determined by ballot vote. The style of the annual meetings was gradually modified to incorporate general oral and poster presentations in addition to Symposia (1969-1974). The publication of annual periodicals in Japanese called Symposia of the Japan Society for Cellular Chemistry (1951-1967) and later Symposia of the Japan Society for Cell Biology (1968-1974) was replaced by a new international journal called Cell Structure and Function initiated in 1975. This reformation made it possible for the Society to participate in the Science Council of Japan in 1975 and finally in 1993 to acquire its own study section of Cell Biology with grants-in-aid from the Ministry of Education and Science, Japan. The JSCB hosted the 3rd International Congress on Cell Biology (ICCB) in 1984 and the 3rd Asian-Pacific Organization for Cell Biology (APOCB) Congress in 1998, thus contributing to the international advancement of cell biology. Now the membership of JSCB stands at approximately 1,800 and the number of presentations per meeting is 300 to 400 annually. Although a good number of interesting and important findings in cell biology have been reported from Japan, the general academic activity of the JSCB is far less than one might expect. This is simply due the fact that academic activity in the field of cell biology in Japan is divided among several other related societies such as the Japan Society for Molecular Biology and the Japan Society for Developmental Biology, among others. (+info)Myocardial lysis in acute rheumatic fever followed by regeneration of cardiac muscle and origin of Aschoff bodies. (7/414)
In acute rheumatic heart disease, lysis of cardiac muscle fibres with or without retention of sarcolemma is found to be the most damaging feature in many cases. In deeper myocardium the cellular lysis often forms anastomosing clefts or sinus-like spaces between surviving muscle bundles and in the outer portion of myocardium cellular lysis may leave the sarcolemma more or less intact. From lysing cardiac muscle fibres there arise dedifferentiated cells with remarkable potentiality for regeneration. For the origin of these dedifferentiated cells, which are often indistinguishable from lymphocytes, no mitosis is seen in cardiac muscle cells. The successive stages of development of muscle cell from these dedifferentiated cells within the remaining or newly formed sarcolemma have been observed in this study. This study infers that the increased number of fibrous septa, when seen, denotes the tracks of previous muscle degeneration and subsequent replacement of it with incomplete muscle regeneration and fibrous tissue formation. In an area of muscle lysis the origin of Aschoff bodies from these dedifferentiated cells has been followed. Ashoff bodies arising in this was behave as an abortive and atypical growth of muscle fibres in a nodular fashion specific to rheumatic fever. (+info)Papanicolaou tests diagnosed as atypical by a cytotechnologist and downgraded to benign by a pathologist: a measure of laboratory quality. (8/414)
Follow-up of Papanicolaou (Pap) tests diagnosed as atypical squamous cells of undetermined significance (ASCUS) or atypical glandular cells of undetermined significance (AGUS) by a cytotechnologist and downgraded to benign by a pathologist has not been measured. Squamous intraepithelial lesion (SIL) follow-up rates were obtained for Pap tests diagnosed as ASCUS (288) or AGUS (94) and downgraded to benign and for Pap tests diagnosed as repair (231). Statistically significant associations were seen between 7 cytotechnologists and between 7 pathologists and ASCUS, AGUS, downgraded ASCUS, and downgraded AGUS rates. The percentage of downgraded ASCUS cases compared with all ASCUS cases per pathologist ranged from 4.8% to 43.7%. Statistically significant associations between pathologists and SIL follow-up rates for downgraded ASCUS diagnoses were seen. The SIL follow-up rate for repair (7.9%) was similar to that for a downgraded ASCUS (11.0%) or AGUS (7.3%). The parameters of downgraded ASCU and AGUS Pap test interpretations are good quality indicators of individual performance and overall laboratory quality. (+info)
Imaris for Cell Biologists - Imaris - Oxford Instruments
UCR plant cell biologist to study how plant stem cells maintain and change thei... ( RIVERSIDE Calif. A plant cell biolo...)
Granule (cell Biology) Resource | Learn About, Share and Discuss Granule (cell Biology) At Popflock.com
Sunday « 58th Annual Scientific Meeting
Cell biologists identify new tumor suppressor for l... ( Cancer and cell biology experts at t...)
Cellular and Micro Biology - Seattle University
Imaging with total internal reflection fluorescence microscopy for the cell biologist | Journal of Cell Science
Yeast becomes a cell biologist | JCB
UC San Diego Names First George Palade Endowed Chair
How Cell Biologists Work: Valentina Greco on cultivating a passionate research team - ASCB
Medical Xpress - cell biologist
Medical Xpress - cell biologists
2011 - 2012 Thursday Series Seminar Archives
Physical and Biological Sciences Division honors three prominent alumni
Post-doc position in Cell Biology at U. of Crete
Research | Department of Cell Biology at Johns Hopkins University School of Medicine
Computational cell biology at the home of the helix | EMBO Reports
James E Rothman, PhD > Molecular Cell Biology, Genetics & Development | Biological and Biomedical Sciences | Yale...
James E Rothman, PhD > Biological & Biomedical Sciences | Yale...
Welcome to the Department of Anatomy and Cell Biology
Scientists solve decades-old cell biology puzzle
Cell Culture Inside Eurkaryote Cell Biology Humor - Words & Unwords
VIDEO: Newly discovered form of cell division may help ward off cancer : Spoonful of Medicine
Bruce H. Lipton, PhD - SoulSpring - A hub for conscious insights on all things life, wellness, love, transformation and...
Dr. Lauren Flynn awarded CFI funding to study fat-derived stem cells - Anatomy and Cell Biology - Western University
Professor Titia Sixma, PhD - Mission Therapeutics
One Form of Neuron Turned into Another in Brain - Metanexus
Division of Anatomy and Cell Biology - Rush University - Graduate Programs and Degrees
Learning biology | Statistical Biophysics Blog
PCB 4023 : Molecular and Cell Biology - FAU - Page 1 - Course
Associate Scientist/Scientist, Functional Genomics | Genomeweb
Fluorescence Microscopy Solutions for Today and the Future | Bruker
Stanford CIRM Training Program | Californias Stem Cell Agency
Eyes News | SciTechDaily
Beyond the Identification of Transcribed Sequences: Functional and Expression Analysis
Mitochondria - Immo E. Scheffler - Google Libros
Spinning-disk microscope offers window into the center of a cell
Institute awarded pediatric brain cancer research grant
Epithelial Cell Culture A Practical Approach PDF Book - Mediafile Sharing
Thinking Big | Genome Canada
August 2016 - Weeding the Gems
The informational content of gradients of Wnt proteins. - Semantic Scholar
Molecular Biology & Genetics, News & Press - A Blog by Fausto Intilla (WWW.OLOSCIENCE.COM): When Intestinal Bacteria Go Surfing...
Anniversary paper on Billingham (1956) | Philosophical Transactions of the Royal Society B: Biological Sciences
VR app gives students a new way to see inner workings of cells | Folio
George Dickson
Radiation from Mammograms Can Cause Breast Cancer - Adjustments for Life
Book Utopianism And Marxism (Ralahine Utopian Studies)
Quantification of Cell Edge Velocities and Traction Forces Reveals Distinct Motility Modules during Cell Spreading | Academic...
Development and Implementation of College and University Curricula Concerning Stem Cell Science and Related Ethical, Legal and...
Download New Frontiers Of Molecular Epidemiology Of Infectious Diseases
DI] miserable opas (cell biology course ?)
W:\aerosol\passion | Wildstylers
Women In Cell Biology Medal For Victoria Cowling : News : University of Dundee
Dr. Jason E. Heindl Named Assistant Professor of Biology at USciences | University of the Sciences | Philadelphia, PA
Assistant Professor of Biology - Rollins College (2 positions) - Jobs - ZFIN Community Wiki
Epub New Frontiers In Resilient Aging: Life Strengths And Well Being In Late Life
Visiting Professor Christiana Ruhrberg - FOR2240
Internetquellen-Führer: Suche - Virtuelle Fachbibliothek Biologie (vifabio)
Dr Mark R Philips
Download Algorithms In A Nutshell 2Nd Edition A Desktop Quick Reference
Harris H. Wang | Data Science Institute
Kevin Brown, Ph.D.
UAB - Magazine - UAB Magazine Online Features
George Emil Palade - Vikipedi
Committee on Development, Regeneration, and Stem Cell Biology - University of Chicago - Graduate Programs and Degrees
ASCB 2016 meeting (San Francisco, Dec 3 - 7) - PLOS Biologue
ECHO, the executable CHOndrocyte - Research - Aarhus University
Dr Neil Hotchin - School of Biosciences - University of Birmingham
bone marrow transplant
Cell biology course 5 - intracellular compartments and protein transport summary - Course 5 Cell Biology (LS5C) - Stuvia
Stem Cells and Aging: How Cellular Stress Affects Aging - Health Extension Salons
Cell Biology · Courses · Courses & Schedules · Keene State College
Interviews | Journal of Cell Science
Image analysis in fluorescence microscopy: bacterial dynamics as a case study. | Lewis-Sigler Institute
Biologists capture cells elusive motor on videotape, solving the mystery of its deployment
Primary Faculty/Secondary Faculty | Department of Pharmacology
Stephen B. Deitz, Ph.D.
Joshua LaBaer, MD, Ph.D. | National Biomarker Development Alliance (NBDA)
Researchers Recreate Genetic Disorder In The Lab - Redorbit
Biological Sciences Division | The University of Chicago
Howard Hughes Medical Institute Names Two UCSF Scientists as New Investigators | UC San Francisco
Monolithic PDMS passband filters for fluorescence detection
PRIMARY CILIA
The Mini Lungs and Other Organoids Helping to Beat COVID -
- Medtelligence
Researchers tap into cell power to create building skins that adapt to heat/light of environment | EurekAlert! Science News
Interviews with Nutritional Experts: How Vitamin E Prevents Heart Disease , Interview with Dr. David Janero as interviewed...
BUILDING BROKEN HEART - NamesakExperT
AANS Neurosurgeon Mice on Wheels Show Scientists How Exercise Benefits Their Brains - AANS Neurosurgeon
A simple and accurate rule-based modeling framework for simulation of autocrine/paracrine stimulation of glioblastoma cell...
Department of Microbiology & Immunology
Under the skin and out in the world
Uncategorized
Systematics (ref. ID; 4926)
Mind Your Head!: What Makes You Uniquely You?
Myocyte - Wikipedia
Immune cells gobble out-of-control fibroblasts when dont-eat-me signal is blocked - Scope
Wear your science - or a cross-section of it - bioephemera
Guanches
Cell Biology, Published Online October 26, 2017 Galindo, Juan de Abreu (1999-01-01). "VII". The History of the Discovery and ... Current Biology. Cell Press. 27 (21): 3396-3402. doi:10.1016/j.cub.2017.09.059. PMID 29107554. Retrieved July 13, 2020. Secher ... BMC Evolutionary Biology. BioMed Central. 9 (181): 181. doi:10.1186/1471-2148-9-181. PMC 2728732. PMID 19650893. Fregel, Rosa; ... BMC Evolutionary Biology. BioMed Central. 14 (109): 109. doi:10.1186/1471-2148-14-109. PMC 4062890. PMID 24885141. Roman Trade ...
Cav1.2
Cahalan MD (Oct 2010). "Cell biology. How to STIMulate calcium channels". Science. 330 (6000): 43-4. doi:10.1126/science. ... Cav1.2 channels are arranged in cluster of eight, on average, in the cell membrane. When calcium ions bind to calmodulin, which ... Calcium channels mediate the influx of calcium ions (Ca2+) into the cell upon membrane polarization (see membrane potential and ... Cav1.2 is widely expressed in the smooth muscle, pancreatic cells, fibroblasts, and neurons. However, it is particularly ...
Centromere
Cell Biology. Philadelphia: Saunders. pp. 200-203. ISBN 978-1-4160-2255-8. Pollard, TD (2007). Cell Biology. Philadelphia: ... Dalal, Yamini (2009). "Epigenetic specification of centromeres". Biochemistry and Cell Biology. 87 (1): 273-82. doi:10.1139/O08 ... Molecular Cell Biology (6th ed.). New York: W.H. Freeman. ISBN 978-0-7167-7601-7. Nagaki, Kiyotaka; Cheng, Zhukuan; Ouyang, Shu ... Essential Cell Biology (4 ed.). New York, NY: Garland Science. p. 183. ISBN 978-0-8153-4454-4. Pollard, T.D. (2007). ...
Western Hunter-Gatherer
Current Biology. Cell Press. 27 (4): 576-582. doi:10.1016/j.cub.2016.12.060. PMC 5321670. PMID 28162894. Kashuba, Natalija (May ... Current Biology. Cell Press. 27 (14): 2185-2193. doi:10.1016/j.cub.2017.06.022. PMID 28712569. Anthony, David (Spring-Summer ... PLOS Biology. PLOS. 16 (1): e2003703. doi:10.1371/journal.pbio.2003703. PMC 5760011. PMID 29315301. Haak, Wolfgang (June 11, ... Communications Biology. Nature Research. 2 (105): 185. doi:10.1038/s42003-019-0399-1. PMC 6520363. PMID 31123709. Lazaridis, ...
Daniel Colón-Ramos
Daniel Alfonso Colón-Ramos is the McConnell Duberg Professor of Neuroscience and Cell Biology at Yale University School of ... "Home > Colón-Ramos Lab , Cell Biology , Yale School of Medicine". medicine.yale.edu. Retrieved 2018-12-25. Santella, Anthony; ... American Society for Cell Biology, 2016 Early Career Award for Public Engagement with Science, American Association for the ... where his lab studies the cell biology of the synapse during development and learning. He is also the founder of the nonprofit ...
List of Nobel laureates affiliated with Harvard University
"James E Rothman, PhD > Rothman Lab , Cell Biology , Yale School of Medicine". medicine.yale.edu. Retrieved 2018-02-05. ... Greenberg, Philip D. (2011-12-27). "Ralph M. Steinman: A man, a microscope, a cell, and so much more". Proceedings of the ...
University of Strathclyde Faculty of Science
Research within the Institute is advanced through six Research Groups: • Cardiovascular Research • Cell Biology • Infection, ... the study of how the microbial cell functions biochemically) again at University of Glasgow. The professor also works with the ... Scottish Qualifications Authority in creating the new Curriculum For Excellence Framework in Biology.[citation needed] The ...
Genetic studies on Sami
Current Biology. Cell Press. 19 (20): 1758-1762. doi:10.1016/j.cub.2009.09.017. PMC 4275881. PMID 19781941. Mittnik, Alisa ( ...
List of Nobel laureates affiliated with Stanford University
"CV (Randy W. Schekman)" (PDF). "James E Rothman, PhD > Rothman Lab , Cell Biology , Yale School of Medicine". medicine.yale.edu ...
List of Nobel laureates affiliated with Princeton University
"James E Rothman, PhD > Rothman Lab , Cell Biology , Yale School of Medicine". medicine.yale.edu. Retrieved 2018-02-05. "The ...
List of Nobel laureates affiliated with Columbia University
"James E Rothman, PhD > Rothman Lab , Cell Biology , Yale School of Medicine". medicine.yale.edu. Retrieved 2018-02-05. "Richard ... "LEFKOWITZ BIO". HHMI. Retrieved 2018-01-15. "CV (Martin Chalfie)". "CV (Robert H. Grubbs)" (PDF). "William S. Knowles - ...
Schindleria
Burke, Jack D. (1970). Cell Biology. Williams and Wilkins. p. 200. Retrieved 2009-01-16. CS1 maint: discouraged parameter (link ...
Melissa Little
She is the serving theme director of Cell Biology at the Murdoch Childrens Research Institute and directs the MCRI Stem Cell ... Recapitulating the development in human pluripotent stem cells". Developmental Biology. The Development of Stem Cell-derived ... "Cell Biology , Murdoch Childrens Research Institute". www.mcri.edu.au. Retrieved 29 August 2017. "Professor Melissa Little , ... Professor Melissa Little FAA FAHMS is an Australian scientist and academic, currently Theme Director of Cell Biology, heading ...
Shahrekord University
... embryo and stem cell biology and technology Department of molecular and cellular genetics in domestic animal reproduction ... Production of cell lines of bone marrow mesenchymal stem cells and their differentiation to bone and adipose cells · ... Animal Bio-systematics(MSc), Plant Biology(BSc), and Animal Biology (BSc) degrees. 2. Department of Genetics Genetics ... Departments: 1. Department of Biology Biology department offers the Biochemistry (MSc and PhD), Botanical Physiology (MSc and ...
Exosite
Biology. Cell.com. 16 (4): 442-51. doi:10.1016/j.chembiol.2009.03.007. PMID 19389630. Retrieved 11 May 2013. CS1 maint: ...
Glossary of medicine
... is a branch of biology that studies the structure and function of the cell, which is the basic unit of life. Cell biology is ... Beta cell - Beta cells (β cells) are a type of cell found in pancreatic islets that synthesize and secrete insulin. Beta cells ... White blood cell - White blood cells (WBCs), also called leukocytes or leucocytes, are the cells of the immune system that are ... All white blood cells are produced and derived from multipotent cells in the bone marrow known as hematopoietic stem cells. ...
Scandinavian Hunter-Gatherer
Current Biology. Cell Press. 19 (20): 1758-1762. doi:10.1016/j.cub.2009.09.017. PMC 4275881. PMID 19781941. Mathieson, Iain ( ... In a genetic study published in PLOS Biology in January 2018, the remains of seven SHGs were examined. All three samples of Y- ... PLOS Biology. PLOS. 16 (1): e2003703. doi:10.1371/journal.pbio.2003703. PMC 5760011. PMID 29315301. Haak, Wolfgang (June 11, ... PLOS Biology. 16 (1): e2003703. doi:10.1371/journal.pbio.2003703. ISSN 1545-7885. PMC 5760011. PMID 29315301. Lazaridis, Iosif ...
Cdc6
Cell biology. Saunders Elsevier. pp. 766-767. ISBN 1-4160-2255-4. Bell SP, Dutta A (2002). "DNA replication in eukaryotic cells ... Cdc6, or cell division cycle 6, is a protein in eukaryotic cells. It is mainly studied in the budding yeast Saccharomyces ... CDC6 is normally present at high levels during the G1 phase of the cell cycle. This is partly because the CDC6 gene is only ... Cell. 11 (5): 1673-85. doi:10.1091/mbc.11.5.1673. PMC 14875. PMID 10793143. Bueno A, Russell P (June 1992). "Dual functions of ...
Comb Ceramic culture
Current Biology. Cell Press. 27 (14): 2185-2193. doi:10.1016/j.cub.2017.06.022. PMID 28712569. Zvelebil, Marek (1997). "Pitted ...
List of Nobel laureates by university affiliation
"James E Rothman, PhD > Rothman Lab , Cell Biology , Yale School of Medicine". medicine.yale.edu. Retrieved 5 February 2018. ... "History of the LMB - MRC Laboratory of Molecular Biology". MRC Laboratory of Molecular Biology. Retrieved 16 January 2018. " ... "Fast Facts - MRC Laboratory of Molecular Biology". MRC Laboratory of Molecular Biology. Retrieved 16 January 2018. " ... "Postdoctoral Opportunities - MRC Laboratory of Molecular Biology". MRC Laboratory of Molecular Biology. Retrieved 15 March 2018 ...
Haplogroup R1a
July 24, 2017). "Extensive Farming in Estonia Started through a Sex-Biased Migration from the Steppe". Current Biology. Cell ... 2003). "A Y Chromosome Census of the British Isles" (PDF). Current Biology. 13 (11): 979-84. doi:10.1016/S0960-9822(03)00373-7 ... 2017). "A genetic chronology for the Indian Subcontinent points to heavily sex-biased dispersals". BMC Evolutionary Biology. 17 ... BMC Biology. 8 (1): 15. doi:10.1186/1741-7007-8-15. PMC 2838831. PMID 20163704. Archived from the original on 27 April 2011. Di ...
Haplogroup I-M253
April 2019). "Survival of Late Pleistocene Hunter-Gatherer Ancestry in the Iberian Peninsula". Current Biology. Cell Press. 29 ... May 2003). "A Y chromosome census of the British Isles". Current Biology. 13 (11): 979-84. doi:10.1016/S0960-9822(03)00373-7. ... Current Biology, vol. 20 (February 23, 2010), R174-R183. yDNA Haplogroup I: Subclade I1, Family Tree DNA, Batini C, Hallast P, ... Current Biology. 19 (20): 1758-62. doi:10.1016/j.cub.2009.09.017. Malmström H, Günther T, Svensson EM, Juras A, Fraser M, ...
Funnelbeaker culture
Current Biology. Cell Press. 19 (20): 1758-62. doi:10.1016/j.cub.2009.09.017. PMID 19781941. S2CID 9487217. Retrieved July 16, ... BMC Evolutionary Biology 10, no. 36, pp. 1-11. Itan, Yuval; Powell, Adam; Beaumont, Mark A.; Burger, Joachim; Thomas, Mark G. ( ... 2009). "The Origins of Lactase Persistence in Europe". PLOS Computational Biology. 5 (8): e1000491. doi:10.1371/journal.pcbi. ...
FMRFamide in Biomphalaria glabrata
Darnell, J. E.; Lodish, H. F. & Baltimore, D. (1990). "Molecular cell biology". Scientific American Books: 302-312. Kempf SC, ... Fields S, Johnston M (Mar 2005). "Cell biology. Whither model organism research?". Science. 307 (5717): 1885-6. doi:10.1126/ ... The cell sends a single process on each side and each process follows the body curvature. As these processes elongate, two ... as the first FMRFamide immunoreactive cell appears at 25-28% of development and is located at the extreme posterior of the ...
Cpf1
CRISPR CRISPR/Cpf1 Cas9 Genome editing Pollard, T.D. (2007). Cell Biology. Philadelphia: Saunders. pp. 200-203. ISBN 978-1-4160 ... Cell Biology. 29 (12): 1305-12. doi:10.1016/S1357-2725(97)00085-X. PMC 2002184. PMID 9570129. Karin M (Feb 1990). "Too many ... Cell. 163 (3): 759-771. doi:10.1016/j.cell.2015.09.038. PMC 4638220. PMID 26422227. Using Cpf1 for CRISPR published by " ... In molecular biology, CRISPR-associated endonuclease in Prevotella and Francisella 1 or Cpf1 is a single RNA-guided ...
Sarmatians
Current Biology. Cell Press. 29 (14): 2430-2441. doi:10.1016/j.cub.2019.06.019. PMID 31303491. Retrieved July 4, 2020. Harmatta ... A genetic study published in Current Biology in July 2019 examined the remains of nine Sarmatians. The five samples of Y-DNA ...
Sámi people
Current Biology. Cell Press. 19 (20): 1758-1762. doi:10.1016/j.cub.2009.09.017. PMC 4275881. PMID 19781941. Mittnik, Alisa ( ... Current Biology. 29 (10): 1701-1711.e16. doi:10.1016/j.cub.2019.04.026. ISSN 0960-9822. PMC 6544527. PMID 31080083. "The ski- ...
Early European Farmers
July 24, 2017). "Extensive Farming in Estonia Started through a Sex-Biased Migration from the Steppe". Current Biology. Cell ... Current Biology. Cell Press. 27 (4): 576-582. doi:10.1016/j.cub.2016.12.060. PMC 5321670. PMID 28162894. Juras, Anna; et al. ( ... Current Biology. Cell Press. 27 (12): 1801-1810. doi:10.1016/j.cub.2017.05.023. PMC 5483232. PMID 28552360. Hofmanová, Zuzana; ...
Mycocepurus
Current Biology. Cell Press. 24 (17): 2047-2052. doi:10.1016/j.cub.2014.07.048. PMID 25155509. Media related to Mycocepurus at ...
Kunda culture
Current Biology. Cell Press. 27 (4): 576-582. doi:10.1016/j.cub.2016.12.060. PMC 5321670. PMID 28162894. Mathieson, Iain ( ...
Bile acid
"ACS Chemical Biology. 11 (10): 2908-2914. doi:10.1021/acschembio.6b00624. PMC 5074845. PMID 27571266.. ... Cell signallingEdit. Bile acids have metabolic actions in the body resembling those of hormones, acting through two specific ... Bile acid synthesis occurs in liver cells, which synthesize primary bile acids (cholic acid and chenodeoxycholic acid in humans ... Exposure of colonic cells to high DCA concentrations increase formation of reactive oxygen species, causing oxidative stress, ...
Craniosynostosis
Lenton KA, Nacamuli RP, Wan DC, Helms JA, Longaker MT (2005). "Cranial suture biology". Current Topics in Developmental Biology ... Certain cells in the brain respond specifically to an increase of CO2 in the blood.[4][24] The response involves vasodilatation ... Advances in the fields of molecular biology and genetics, as well as the use of animal models have been of great importance in ... Frontiers of Oral Biology. 12 (1): 107-43. doi:10.1159/000115035. ISBN 978-3-8055-8326-8. . PMID 18391498.. ...
Plasma cell
Kierszenbaum, Abraham L. (2002). Histology and cell biology: an introduction to pathology. St. Louis: Mosby. p. 275. ISBN 0-323 ... Plasma cells, also called plasma B cells, plasmocytes, plasmacytes, or effector B cells, are white blood cells that secrete ... In humans, CD27 is a good marker for plasma cells, naive B cells are CD27-, memory B-cells are CD27+ and plasma cells are ... Germinal center B cells may differentiate into memory B cells or plasma cells. Most of these B cells will become plasmablasts ( ...
T细胞 - 维基百科,自由的百科全书
Bacteria, mucosal-associated invariant T cells and MR1. Immunology and Cell Biology. November 2010, 88 (8): 767-9. PMID ... T Cells to protect tumour cells. Nature Communications. March 2018, 9 (1): 948. PMC 5838096. PMID 29507342. doi:10.1038/s41467- ... 细胞毒性T细胞(CTLs, killer T cells)负责杀伤被病毒感染的细胞和癌细胞,在对器官移植的免疫排斥中也有参与。其特点在于细胞表面的CD8蛋白质。它通过识别所有有核细胞表
N-myristoyltransferase 1
Cell. Biochem. 204 (1-2): 135-55. doi:10.1023/A:1007012622030. PMID 10718634. Geyer M, Fackler OT, Peterlin BM (2001). " ... N-myristoyltransferase 2 Molecular and Cellular Biology portal. ... and membrane association in COS cells". Proc. Natl. Acad. Sci. ... Wice BM, Gordon JI (1992). "A strategy for isolation of cDNAs encoding proteins affecting human intestinal epithelial cell ... "Antimyristoylation of the gag proteins in the human immunodeficiency virus-infected cells with N-myristoyl glycinal ...
Type 2 diabetes
Seminars in Cell and Developmental Biology. doi:10.1016/j.semcdb.2019.12.002. PMID 31831356.. ... a type 2 diabetic will have lost about half of their beta cells.[52] Fatty acids in the beta cells activate FOXO1, resulting in ... Type 2 diabetes is due to insufficient insulin production from beta cells in the setting of insulin resistance.[13] Insulin ... In the early stages of insulin resistance, the mass of beta cells expands, increasing the output of insulin to compensate for ...
Eating
"Integrative and Comparative Biology. 47 (1): 147-163. doi:10.1093/icb/icm016. PMID 21672827.. ... The brain detects insulin in the blood, which indicates that nutrients are being absorbed by cells and a person is getting full ... Schreiber, Elizabeth Anne; Joanna Burger (2001). Biology of Marine Birds. Boca Raton: CRC Press. ISBN 0-8493-9882-7.. ... When the glucose levels of cells drop (glucoprivation), the body starts to produce the feeling of hunger. The body also ...
Indinavir
"Journal of Molecular Biology. 354 (4): 789-800. doi:10.1016/j.jmb.2005.09.095. PMC 1403828. PMID 16277992.. ... 1156 patients with a mean of 87 CD4 cell counts and mean viral load of 100,000 copies/ml were randomized to one of the two ... Viral resistance to the drug leads to the drug becoming useless since the virus evolves to have cells that are able to resist ... There were higher CD4 cell counts and less viral load in patients assigned to the three-drug group, proving that a three-drug ...
Catenin
Nature Reviews Molecular Cell Biology. 10 (4): 276-86. doi:10.1038/nrm2654. PMID 19305417. MacDonald BT, Tamai K, He X (July ... F9 embryonal carcinoma cells are similar to the P19 cells shown in Figure 1 and normally have cell-to-cell adhesion mediated by ... A tumor cell line with defective δ-catenin, low levels of E-cadherin and poor cell-to-cell adhesion could be restored to normal ... providing the cell with a means of stable cell adhesion. However, decreases in this adhesion ability of the cell has been ...
Centrifugation
Cells are homogenised in a blender and filtered to remove debris. *The homogenised sample is placed in an ultracentrifuge and ... Current Opinion in Chemical Biology, Vol. 10, 2006. pp. 430-436.. *Dam, J., Velikovsky, C.A., Mariuzza R.A., et al. ... General method of fractionation: Cell sample is stored in a suspension which is: *Buffered - neutral pH, preventing damage to ... This method is commonly used to separate organelles and membranes found in cells. Organelles generally differ from each other ...
Nespecifična monooksigenaza
Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins ( ... Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley- ... Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). ... Nebert, D.W. and Gelboin, H.V. (1968). "Substrate-inducible microsomal aryl hydroxylase in mammalian cell culture. I. Assay and ...
Αμινά Γκουρίμπ - Βικιπαίδεια
Gurib-Fakim, A.; Sewraj, M.; J., Gueho; Dulloo, E.. «Medicinal Plants of Rodrigues». Pharmaceutical Biology. doi:10.1076/phbi. ... In vitro modulation of oxidative burst via release of reactive oxygen species from immune cells by extracts of selected ... Gurib-Fakim, A.; Gueho, J.; Sewraj-Bissoondoyal, M.. «The Medicinal Plants of Mauritius - Part 1». Pharmaceutical Biology. doi: ... Pharmaceutical Biology. doi:10.1076/phbi.36.3.153.6345. ... Pharmaceutical Biology. doi:10.1076/phbi.37.3.202.6300. ...
Lewis Joel Greene
Greene received a BA in liberal arts from Amherst College in 1955 and a PhD in biochemistry and cell biology at Rockefeller ... where he is a full professor of cell and molecular biology and head of the Center for Protein Chemistry of Hemocentro de ... After his doctorate, he went to work for 12 years as a tenured researcher in the Department of Biology at Brookhaven National ...
Labium - Simple English Wikipedia, the free encyclopedia
This short article about biology can be made longer. You can help Wikipedia by adding to it. ... Sertoli cell - Spermatic cord - Testicles (testes) - Urethra - Vasa deferentia ...
QIAGEN Silicon Valley
... and is purchased by QIAGEN in May of the same year Systems biology Bioinformatics Computational genomics Computational biology ... BD Cell Pathways "Ingenuity Systems Announces Immediate Availability Of The Ingenuity Pathways Knowledge Base" (Press release ... The software has been cited in thousands of scientific molecular biology publications and is one of several tools for systems ... "Best of Show: Life Science Software & Informatics". Bio-IT World. June 13, 2007. Retrieved April 7, 2012. "Ingenuity Systems ...
Cell membrane - Simple English Wikipedia, the free encyclopedia
Kimball's biology pages, Cell membranes *↑ Singleton P, (1999). Bacteria in biology, biotechnology and medicine (5th ed.). New ... In all cells, the cell membrane separates the cytoplasm inside the cell from its surroundings. Animal cells are contained in ... The cell membrane is a thin flexible layer around the cells of all living things. It is sometimes called the plasma membrane or ... Molecular cell biology. 4th ed, New York: Scientific American Books. ISBN 0716731363 ...
UDP-N,N'-diacetilbacilozaminska 2-epimeraza (hidroliza)
Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins ( ... Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley- ... Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). ...
Chi's Sweet Home
Cells at Work! Code Black (2018). *Gurazeni: Pa League-hen (2018). *Cells at Work! Baby (2019) ... Bio Hunter (1995). *Birdy the Mighty (1996-1997). *Night Warriors: Darkstalkers' Revenge (1997-1998) ...
Streptococcus pneumoniae
Invasins, such as pneumolysin, an antiphagocytic capsule, various adhesins, and immunogenic cell wall components are all major ... and white blood cells to fill the alveoli. This condition is called pneumonia.[20] It is susceptible to clindamycin.[21] ...
Positron emission tomography
"Magnetic Resonance Materials in Physics, Biology and Medicine. 26 (1): 99-113. doi:10.1007/s10334-012-0353-4. ISSN 0968-5243. ... This tracer is a glucose analog that is taken up by glucose-using cells and phosphorylated by hexokinase (whose mitochondrial ... This means that FDG is trapped in any cell that takes it up until it decays, since phosphorylated sugars, due to their ionic ... Qi, J.; R. Leahy (2006). "Iterative reconstruction techniques in emission computed tomography". Physics in Medicine and Biology ...
Leaf
... epidermal hair cells (trichomes), cells in the stomatal complex; guard cells and subsidiary cells. The epidermal cells are the ... "School of Biology, Georgia Institute of Technology. Retrieved 12 March 2017.. *. Geneve, Robert. "Leaf" (PDF). PLS 220: ... Cells that bring water and minerals from the roots into the leaf.. Phloem. Cells that usually move sap, with dissolved sucrose( ... Its cells contain many more chloroplasts than the spongy layer. Cylindrical cells, with the chloroplasts close to the walls of ...
Ebola
... dendritic cells and other cells including liver cells, fibroblasts, and adrenal gland cells.[93] Viral replication triggers ... Klenk, Hans-Dieter; Feldmann, Heinz (2004). Ebola and Marburg viruses: molecular and cellular biology (Limited preview). ... doi:10.1016/j.cell.2014.10.006. PMC 4243531. PMID 25417101.. *^ a b c d e f g h Kühl A, Pöhlmann S (September 2012). "How Ebola ... liver cells, and several types of immune cells such as macrophages, monocytes, and dendritic cells are the main targets of ...
Oligosaccharyltransferase
"Cell. 136 (2): 272-83. doi:10.1016/j.cell.2008.11.047. PMC 2859625. PMID 19167329.. ... "J. Cell Biol. 161 (4): 715-25. doi:10.1083/jcb.200301043. PMC 2199356. PMID 12756234.. ... the hepatitis C virus envelope protein E1 occurs posttranslationally in a mannosylphosphoryldolichol-deficient CHO mutant cell ...
Pre-Bötzinger complex
It also contains pacemaker cells and nonpacemaker cells that initiate spontaneous breathing. Research is being conducted on the ... Advances in experimental medicine and biology. 758: 115-22. PMID 23080151. Stafstrom CE. Persistent Sodium Current and Its Role ... It is one of the four cell groups of the Ventral Respiratory Group (VRG). It is hypothesized that the pre-Bötzinger complex is ... which helps cell regenerate its bursts. The ratio between inward and outward currents helps determine the activity of pacemaker ...
Respiration
BiologyEdit. *Cellular respiration, the process in which nutrients are converted into useful energy in a cell *Anaerobic ... Respiration (physiology), transporting oxygen and carbon dioxide between cells and the external environment *Respiratory system ...
Amphibian - Simple English Wikipedia, the free encyclopedia
Cell Press. doi:10.1016/j.isci.2020.101234. Retrieved July 7, 2020.. Cite journal requires ,journal=. (help). ... Biology of amphibians. Johns Hopkins University Press. ISBN 978-0-8018-4780-6 ... Experimental approaches to conservation biology. University of California Press. ISBN 978-0-520-24024-7 ... bullfrogs are dissected in biology classes. Usually, this is done in grammar school.[32]p85 The dissecting is a method for ...
Chloroplast DNA
Alberts B (2002). Molecular biology of the cell (4. ed.). New York [u.a.]: Garland. ISBN 978-0-8153-4072-0. .. ... Because the cell acquiring a chloroplast already had mitochondria (and peroxisomes, and a cell membrane for secretion), the new ... Biology 8th Edition Campbell & Reece. Benjamin Cummings (Pearson). 2009. p. 516.. *^ a b Kobayashi T, Takahara M, Miyagishima ... and therefore topologically outside of the cell, because to reach the chloroplast from the cytosol, you have to cross the cell ...
質譜法 - 維基百科,自由的百科全書
Methods in molecular biology. Methods in Molecular Biology. 2009, 600: 269-281. ISBN 978-1-60761-453-1. PMID 19882135. doi: ... 細胞損傷(英語:Cell damage). *傷口癒合 ...
Sandhya Srikant Visweswariah
Indian Society of Cell Biology[19] (1995-present) and the Society of Research in Reproduction, India (1994-present). ... Basu et al (2014) Intestinal cell proliferation and senescence is regulated by receptor guanylyl cyclase C and p21 J. Biol. ... the American Society for Biochemistry and Molecular Biology[21] (ASBMB), and the American Society for Microbiology (ASM).[22] ... Additionally, she is a member of Guha Research Council, India (1997-present), the Alliance for Cell Signalling[20] (1997- ...
Barnacle
"Biology of Barnacles". Museum Victoria. 1996. Archived from the original on February 17, 2007. Retrieved April 20, 2012.. ... Such barnacles feed by extending thread-like rhizomes of living cells into their hosts' bodies from their points of attachment. ... Leone, Stacy E. (2008). Predator Induced Plasticity in Barnacle Shell Morphology (Master of Arts in Biology thesis). Central ... 1987-06-01). Barnacle Biology. Crustacean Issues. 5. Leiden, Netherlands: CRC Press / A. A. Balkema. ISBN 978-90-6191-628-4. . ...
Cell (biology) - Wikipedia
In mammals, major cell types include skin cells, muscle cells, neurons, blood cells, fibroblasts, stem cells, and others. Cell ... Cells are often called the "building blocks of life". The study of cells is called cell biology, cellular biology, or cytology ... Cell wall. Further information: Cell wall. Many types of prokaryotic and eukaryotic cells have a cell wall. The cell wall acts ... Main article: Cell division. Cell division involves a single cell (called a mother cell) dividing into two daughter cells. This ...
cell biology | ScienceBlogs
In cell biology or molecular biology labs the emphasis is on working sterile, quickly and reproducibly. So companies have been ... tags: The Nature of Cell Science, cell biology, microscopy, research, science, music, Venetian Snares, Szamár Madár, field ... tags: Lab Trash, recycle, molecular biology, cell biology, streaming video Ive been telling you about the perils of plastics, ... Scientists are reporting that they have made a living cell from DNA that was originally synthesized in a lab. This isnt quite ...
CELL BIOLOGY-2
Cell biology | NIST
Chapter I: Human cells dont grow randomly (aka Gretas academic adventure).. Scientists need to grow cells with structures ... Chapter II: Human cells dont grow alone (aka Gretas NIST experience).. In common practices for counting cells, scientists ... Researchers also often use toxic dyes for labeling live and dead cells. These dyes kill the cells and essentially end the ... Scientists can combine cells and the scaffolds they grow on into structures that can repair or restore damaged or lost tissue ...
For authors : Immunology & Cell Biology
... with a particular emphasis on its cell biology. Areas that are covered include but are not limited to: Cellular immunology, ... Immunology and Cell Biology focuses on the general functioning of the immune system in its broadest sense, ... That Immunology & Cell Biology has an impact factor of 4.557. Top of page Top of page Submitting an article. To read about how ... Immunology & Cell Biology has adopted Springer Natures online submission system, which allows authors to submit papers via the ...
Cell Biology | Journal | Springer
Cell Biology and Toxicology Wang, X. (Ed) Cell Biology and Toxicology (CBT) is an international journal focused on clinical and ... Cancer Cell International Coppola, D. (Ed) Cancer Cell International publishes articles on all aspects of cancer cell biology, ... Stem Cell Reviews and Reports Ratajczak, M. Z. (Ed) The purpose of Stem Cell Reviews and Reports is to cover contemporary and ... Stem Cell Research & Therapy OBrien, T. (Ed), Tuan, R. S. (Ed) Stem Cell Research & Therapy is the major forum for ...
Cell and Tissue Biology
... in vivo and in cell culture, which offers insight into the structure and functions of the live cell as a whole. Typically, the ... The journal Cell and Tissue Biology publishes research on animal and plant cells, ... The journal Cell and Tissue Biology publishes research on animal and plant cells, in vivo and in cell culture, which offers ... Cell and Tissue Biology. Editor-in-Chief: Nikolai N. Nikolsky. ISSN: 1990-519X (print version). ISSN: 1990-5203 (electronic ...
Structural Cell Biology Group
Scott Williams, Ph.D., is Deputy Chief of the Genome Integrity and Structural Biology Laboratory, head of the Structural Cell ... Deputy Chief, Genome Integrity and Structural Biology Laboratory and Principal Investigator Tel 984-287-3542 [email protected] ... We focus on understanding the mechanisms through which chemically heterogeneous DNA breaks are recognized and repaired in cells ... The Genome Stability Structural Biology Group links insights into the fundamental principles of molecular recognition and ...
Cell and Developmental Biology
... PhDs. The Department of Cell and Developmental Biology has a very ... Developmental and Stem Cell Biology PhD Programme - Supervisors and Research Areas. Prof Jonathan Chubb, LMCB imaging ... Developmental and Stem Cell Biology PhD Programme - How to Apply. Please complete a UCL Graduate Student application form. ... Developmental and Stem Cell Biology PhD Programme - Outline. This programme offers a unique environment with one of the largest ...
Cell biology
... everything you need for studying or teaching Cell biology. ... Immediately download the Cell biology summary, chapter-by- ... Cell biology Summary. Everything you need to understand or teach Cell biology. ... Cytology Cytology is the branch of biology that studies cells, the building blocks of life. The name for this science is ...
Cell biology - Wikipedia
Biology portal Science portal The American Society for Cell Biology Cell biophysics Cell disruption Cell physiology Cellular ... Cell biology (also cellular biology or cytology) is a branch of biology studying the structure and function of the cell, also ... Direct cell-cell contact is when a receptor on a cell binds a molecule that is attached to the membrane of another cell. ... Many techniques commonly used to study cell biology are listed below: Cell culture: Utilizes rapidly growing cells on media ...
Cell (biology) - Wikipedia
In mammals, major cell types include skin cells, muscle cells, neurons, blood cells, fibroblasts, stem cells, and others. Cell ... Cells Alive! Cell Biology in "The Biology Project" of University of Arizona. Centre of the Cell online The Image & Video ... Biology portal Cell cortex Cell culture Cellular model Cytorrhysis Cytoneme Cytotoxicity Human cell Lipid raft Outline of cell ... Some eukaryotic cells (plant cells and fungal cells) also have a cell wall. Inside the cell is the cytoplasmic region that ...
Networks in Cell Biology | SpringerLink
Albert, R. (2005). Scale-free networks in cell biology. J. Cell Sci., 118 (Pt 21):4947-57.PubMedCrossRefGoogle Scholar ... Rodríguez-Caso C., Solé R.V. (2007) Networks in Cell Biology. In: Dubitzky W., Granzow M., Berrar D. (eds) Fundamentals of Data ... Barabasi, A.L. and Oltvai, Z.N. (2004). Network biology: Understanding the cells functional organization. Nat. Rev. Genet., 5( ... In Bonchev, D. and Rouvray, D. H., editors, Complexity in chemistry, biology and ecology. Springer, New York.Google Scholar ...
Category:Cell biology - Wikimedia Commons
... cell biology (sco); Эсийн биологи (mn); cellebiologi (nn); cytologi (nb); sitologiya (az); cell biology (en); علم الأحياء ... Media in category "Cell biology". The following 200 files are in this category, out of 474 total. ... Pages in category "Cell biology". This category contains only the following page. ... biología celular (es); frumulíffræði (is); biologi sel (ms); cell biology (en-gb); Клетъчна биология (bg); biologie celulară ( ...
Category:Cell biology - Wikimedia Commons
biología celular (es); frumulíffræði (is); biologi sel (ms); cell biology (en-gb); Клетъчна биология (bg); Cell biology (simple ... cell biology (sco); Эсийн биологи (mn); cellebiologi (nn); cytologi (nb); sitologiya (az); cell biology (en); علم الأحياء ... File nella categoria "Cell biology". Questa categoria contiene 200 file, indicati di seguito, su un totale di 465. ... Pagine nella categoria "Cell biology". Questa categoria contiene ununica pagina, indicata di seguito. ...
Cell Biology Group - Scientists & Staff
Cell biology - Latest research and news | Nature
Cell biology. Definition. Cell biology is the discipline of biological sciences that studies the structure, physiology, growth ... reproduction and death of cells. Research in cell biology uses microscopic and molecular tools and examines all cell types, ... Collective cell migration and metastases induced by an epithelial-to-mesenchymal transition in Drosophila intestinal tumors ... She is interested in understanding biomechanical regulation of stem cell fate decisions in health and disease. Kates long term ...
Unit 1 Cell Biology - National 5 Biology
Cell ultrastructure and functions to include: cell walls, mitochondria, chloroplasts, cell membrane, vacuole, nucleus, ... Welcome to the Cell Biology Unit...or as we like to call it, What are we made of? In this unit we take your understanding of ... Cell production by cell culture requires aseptic techniques, an appropriate medium and the control of other factors. ... Animal cells can burst or shrink and plant cells can become turgid or plasmolysed in different solutions. ...
luc-berthiaume | Department of Cell Biology
Detection of fatty acylated proteins, chemical biology leading the way Progress in the study of fatty acylation has been ... Simply put, signal transduction is the movement of a signal from outside to inside the cell. It often results in changes in ... 43*. Berthiaume, Luc G. (2013) "Wnt acylation: Seeing is believing" Nature Chemical Biology Published online 24 November 2013 ... in cultured cells and in vivo using click chemistry: H- and N-Ras as a case study" J. Lipid Res. 51, 1566-1580). (* these ...
Cell Biology of Extracellular Matrix | SpringerLink
Embryo biology cell cell biology genetics glycoprotein membrane metabolism molecular biology molecular genetics protein ... We decided that with judicious editing we could present the recent findings in molecular biology within the same cell biology ... Extracellular matrix and cell-matrix interaction are now routine topics in the meetings and annual reviews sponsored by cell ... Research in molecular biology has so advanced the number of known matrix molecules and the topic of gene structure and ...
Induced pluripotent stem cell | biology | Britannica
Induced pluripotent stem cells (iPS cells) differ from embryonic stem cells (ES cells), which form the inner ... iPS cell), immature cell that is generated from an adult (mature) cell and that has regained the capacity to differentiate into ... Induced pluripotent stem cells (iPS cells) differ from embryonic stem cells (ES cells), which form the inner cell mass of an ... Alternative Title: iPS cell. Induced pluripotent stem cell (iPS cell), immature cell that is generated from an adult (mature) ...
jennifer hocking | Department of Cell Biology
J Cell Biol. 2010 Nov 15;191(4):875-90. doi: 10.1083/jcb.201004154. Epub 2010 Nov 8. Erratum in: J Cell Biol. 2010 Dec 27;191(7 ... with the goal of expanding out understanding of the cell biology underlying retinal dystrophies. We use zebrafish as an animal ... Their retinas have an abundance of both rods and cones, allowing us to study both cell types. Further, we have many tools for ... IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation. Oberoi TK, Dogan T, Hocking JC, ...
Cell biology of molybdenum. - PubMed - NCBI
More articles from Cell Biology | PNAS
Single-cell resolution analysis of the human pancreatic ductal progenitor cell niche Mirza Muhammad Fahd Qadir, Silvia Álvarez- ... Cell atlas of aqueous humor outflow pathways in eyes of humans and four model species provides insight into glaucoma ... K6-linked SUMOylation of BAF regulates nuclear integrity and DNA replication in mammalian cells Qiaoyu Lin, Bin Yu, Xiangyang ... Molecular taxonomy of human ocular outflow tissues defined by single-cell transcriptomics - May 21, 2020 ...
Cell Biology News » Topix
News for Cell Biology continually updated from thousands of sources on the web : Building better tiny kidneys to test drugs and ... Topix › Cell Biology News Cell Biology News. News on Cell Biology continually updated from thousands of sources around the net. ... Non-invasive perturbations of intracellular flow reveal physical principles of cell organization Monday Feb 5 , Nature Cell ... Regulation of T cell signalling by membrane lipids Monday Feb 12 , Nature Reviews Immunology , ...
Cell Biology and Cancer
... developed with the National Cancer Institute (NCI) is a creative, inquiry-based ... If you know the author of Cell Biology and Cancer, please help us out by filling out the form below and clicking Send. ... You just viewed Cell Biology and Cancer. Please take a moment to rate this material. ... There are interactive units on the cell cycle, tumor suppressors, proto-oncogenes and their role in the development of cancer. ...
Cell Biology | UC Davis
Cell biologists study these processes and the principles that govern the organization and function of cells within the body. ... Cell biology integrates principles from many disciplines, including chemistry, physics, ... Cells-the basic unit of organization of all life-carry out the fundamental processes necessary for organisms to grow, reproduce ... Cell Biology Cells-the basic unit of organization of all life-carry out the fundamental processes necessary for organisms to ...
GCSE Science Revision - B1: Cell Biology Revision Videos
Cell Biology
Includes bioassays for biologics, cell viability and cytotoxicity assays, genetic reporter assays cell signaling assays, and ... Cell Biology. Cell biology, the study of the structure and function of the cell, encompasses many research areas. Cell biology ... Cell Biology Basics. Cell biology assays are used with cells grown in vitro to help researchers answer questions about the ... Cell biology assays can be used with cellular model systems including :. *monolayer cell cultures - any cell type grown on a ...
Cell & Molecular Biology Program | Science Mission Directorate
Hardware BioCell Habitat BioCell Habitat is a cell culture system capable of supporting complex cell culture experiments. The ... Cell & Molecular Biology Program Hardware. BioCell Habitat. BioCell Habitat is a cell culture system capable of supporting ... including cell biology, microbiology, discovery biology, and drug-testing studies to be conducted on the ISS. Operationally, ... changes in cell cycle, growth and development, and/or genetic abnormality. Applications range from fundamental biology ...
BiochemistryMembraneProteinsDevelopmentalLiving organismsCytologyDifferentiationProteinEukaryotic cellMembranesImmunologyCellular biology2020BiologicalProliferationMoleculesCytoskeletonPhysiology2018TissuesMechanismsNucleusLaboratoryMetabolismStructural BiologyPathwaysBacteriaGeneMitosisAnatomyMicroscopicRegenerative medicineBiologistsChemistryFundamentalResearchersSignal transductionStudy of eukaryotic cellsMitochondriaMicroscopyResearchJournal of Cell BiologyCyclePolarityOrganismDepartment of BiologyTissueBioscienceGenetics and molecular biologySmaller than eukaryotic cellsCancer cell biologyProgenitorProkaryotic and eukaryotic cellsRegulationOrganizationTumorContentScientistsApoptosisProkaryotesGeneticCytoplasmMainMolecular genetics
Biochemistry11
- Cell biology integrates principles from many disciplines, including chemistry, physics, genetics, biochemistry and physiology, for a more complete understanding of cell function. (ucdavis.edu)
- Dr. Korn's laboratory brings the tools of biochemistry and cell biology to focus on three research areas: the role of the actin cytoskeleton in Dictyostelium fruiting body development, the molecular basis of the regulation of actin-activated ATPase activity in myosin II, and the mechanism of association of myosin I with cell membranes. (nih.gov)
- Chemistry is the backbone of Cellular Biology so some knowledge of Biochemistry is necessary for the concepts. (wikiversity.org)
- Research in a selected topic in molecular biology, cell biology and biochemistry. (bu.edu)
- Welcome to the Department of Cell Biology and Plant Biochemistry ! (uni-regensburg.de)
- Read a description of the Cell Biochemistry Section . (nih.gov)
- Welcome to the Department of Molecular Biology, Cell Biology & Biochemistry (MCB), which is the largest on-campus department in the Division of Biology and Medicine. (brown.edu)
- Research in cell biology is closely related to genetics , biochemistry , molecular biology , immunology , and developmental biology . (wikipedia.org)
- The Department of Biochemistry & Molecular Biology offers programs leading to MS, PhD, and MD/PhD degrees, preparing students for successful careers as independent investigators in academia, government, biotechnology, and in teaching in academia, govern. (gradschools.com)
- he Department of Biochemistry and Molecular Biology offers a program of study leading to the Ph.D. degree. (gradschools.com)
- Cell biology encompasses both prokaryotic and eukaryotic cells and can be divided into many sub-topics which may include the study of cell metabolism, cell communication, cell cycle, biochemistry, and cell composition. (wikipedia.org)
Membrane25
- Cells consist of cytoplasm enclosed within a membrane , which contains many biomolecules such as proteins and nucleic acids . (wikipedia.org)
- They are simpler and smaller than eukaryotic cells, and lack a nucleus , and other membrane-bound organelles . (wikipedia.org)
- Enclosing the cell is the cell envelope - generally consisting of a plasma membrane covered by a cell wall which, for some bacteria, may be further covered by a third layer called a capsule . (wikipedia.org)
- Though most prokaryotes have both a cell membrane and a cell wall, there are exceptions such as Mycoplasma (bacteria) and Thermoplasma (archaea) which only possess the cell membrane layer. (wikipedia.org)
- The cell membrane consists of lipids and proteins and is selectively permeable . (google.com)
- Protein fatty acylation is a very unique protein modification that impacts on virtually every aspect of cellular life including the regulation of membrane targeting, apoptosis, cell proliferation, protein-protein interaction, protein stability and protein secretion. (ualberta.ca)
- She has applied her wealth of experience in the cell biology of protein folding and membrane trafficking toward deciphering the mechanisms of prion formation and propagation. (nih.gov)
- As with every cell, the ability of the podocyte to receive signals from the surrounding environment and to translate them to the intracellular milieu is dependent largely on molecules residing on the cell membrane. (nih.gov)
- In this review, we take a membrane biologist's view of the podocyte, examining the many membrane receptors, channels, and other signaling molecules that have been implicated in podocyte biology. (nih.gov)
- Since then, superresolution microscopy techniques, such as STORM and PALM, have become popular methods to study the organization of proteins in the cell membrane. (eurekalert.org)
- Surprisingly, many research groups found that virtually all studied proteins form clusters in the cell membrane. (eurekalert.org)
- For many important problems in medicine and biology, it is crucial to understand the structure of the cell membrane", says Florian Baumgart from the biophysics-research team led by Professor Gerhard Schütz at TU Wien. (eurekalert.org)
- Superresolution microscopy is an ideal tool to study the spatial arrangement of proteins on the cell membrane. (eurekalert.org)
- An intermediate level exploration of cell structure and function including membrane structure, intracellular organelles, membrane trafficking, surface receptors and signal transduction, the cytoskeleton, cell motility and communication, and the cell cycle. (upenn.edu)
- Although mast cells may be activated by a number of stimuli and pathways [ 11 , 12 ], the major mechanism for their activation and subsequent degranulation is through the high-affinity receptor for immunoglobulin E (Fc ε RI), present in the plasma membrane of mast cells, epidermal Langerhans cells, eosinophils, and basophils [ 13 ]. (hindawi.com)
- For reference, parts of chapters 9 (Microscopy), 12 (Protein transport), 13 (Intracellular membrane transport) and 14 (Mitochondria and Chloroplasts) from the book Molecular Biology of the Cell will be used. (rug.nl)
- The cell is a membrane-enclosed body that is the structural and functional unit of living organisms , being the smallest unit that can carry on all life processes, including maintenance, growth, replication, and self-repair. (newworldencyclopedia.org)
- Cell contents are enclosed by a cell surface membrane , a lipid bilayer within which are floating up to thousands of protein molecules. (newworldencyclopedia.org)
- Although some few prokaryotic cells use internal membranes as a site of metabolism, prokaryotic cells characteristically lack internal membrane-bound compartments, while eukaryotic cells have a highly specialized endomembrane system, characterized by regulated traffic and transport vesicles. (newworldencyclopedia.org)
- Thomas Sollner (University of Munich): "The complex organization of eucaryotic cells into various membrane-bound compartments (organelles) requires a very specific targeting of newly synthesized proteins to their final destinations. (the-scientist.com)
- They are known principally for their pivotal role in regulating the actin cytoskeleton, but their ability to influence cell polarity, microtubule dynamics, membrane transport pathways and transcription factor activity is probably just as significant. (nih.gov)
- [9] Eukaryotic cells include animal, plant, fungi, and protozoa cells which all have a nucleus enclosed by a membrane, with various shapes and sizes. (wikipedia.org)
- The main constituents of the general molecular composition of the cell includes: proteins and lipids which are either free flowing or membrane bound, along with different internal compartments known as organelles . (wikipedia.org)
- Prokaryotic cells are distinguished from eukaryotic cells by the absence of a cell nucleus or other membrane bound organelle. (wikipedia.org)
- All chromosomal DNA is stored in the cell nucleus, separated from the cytoplasm by a membrane. (wikipedia.org)
Proteins16
- These are structures (not present in all prokaryotes) made of proteins that facilitate movement and communication between cells. (wikipedia.org)
- In the ultra tiny world of proteins, inside cells, there is little difference between form and function. (scienceblogs.com)
- It is estimated that at least 5% of nuclear encoded proteins are either myristoylated or palmitoylated and yet little is known about the biology of protein fatty acylation. (ualberta.ca)
- Recent breakthroughs in our laboratory and others have led to major improvements in detection and identification of fatty acylated proteins using chemical biology (e.g. publications 29 and 33 below). (ualberta.ca)
- Several proteins have been identified that are capable of inducing or enhancing pluripotency in nonpluripotent (i.e., adult) cells. (britannica.com)
- Pluripotency factors can be introduced into nonpluripotent cells in different ways, such as by plasmids or delivery as proteins or modified RNAs . (britannica.com)
- These are organized into categories such as "cell cycle proteins," "cell movement," etc. and are annotated with brief descriptions of the experiment and a link to the original publication. (merlot.org)
- Fluorescently-labelled intracellular targets can be bleached within a region of interest, followed by imaging in the area to determine kinetic and dynamic properties of proteins and structures in live cells. (zeiss.com)
- In recent years, various research groups have investigated how proteins are distributed on cell membranes. (eurekalert.org)
- mRNAs are the blueprints that specify the structures of all the proteins made in the cell, and represent "transcribed" copies of the corresponding genetic information encoded in specific segments of the genomic DNA in the cell nucleus. (eurekalert.org)
- Thus a complete catalog of the mRNAs in a cell provides a comprehensive view of the proteins that it produces, and tells one what subset of the thousands of genes in the genome are active and how their activity is regulated. (eurekalert.org)
- PAR proteins are essential transducers of spatial information between upstream symmetry-breaking cues and downstream pathways that control polarized processes such as cell migration, asymmetric cell division and tissue architecture. (ucl.ac.uk)
- Students successfully completing this second year module should develop a conceptual understanding of how the different organelles and proteins contribute to the life cycle & functions of an eukaryotic cell. (bangor.ac.uk)
- Topics include electron and fluorescence microscopy of cells/tissues, the use of fluorescent dyes and proteins, special fluorescence approaches such as FRAP (fluorescence recovery after photobleaching), FCS (fluorescence correlation spectroscopy) and FRET (Förster resonance energy transfer), superresolution microscopy, atomic force microscopy and optical tweezers. (rug.nl)
- We study the proteins and genes responsible for differentiation of and/or long-lived survival of antibody-secreting cells. (seattlechildrens.org)
- Identification of the full reprtoires of proteins (full proteomes, including many thousands of proteins) present in samples such as cell lines, tissues or mircoorganisms. (weizmann.ac.il)
Developmental17
- The Department of Cell and Developmental Biology has a very active MPhil/PhD programme. (ucl.ac.uk)
- Select 'Division of Biosciences' for the UCL Department you are applying to and 'Research Degree: Cell and Developmental Biology' for Programme Title. (ucl.ac.uk)
- This programme offers a unique environment with one of the largest and strongest concentrations of high quality developmental and stem cell biologists anywhere in the world. (ucl.ac.uk)
- The programme provides training at the interface between developmental and stem cell biology. (ucl.ac.uk)
- The 3 year version is available in laboratories in the Cell and Developmental Biology Department. (ucl.ac.uk)
- Among the first to discover that possibility was British developmental biologist John B. Gurdon , who in the late 1950s had shown in frogs that egg cells are able to reprogram differentiated cell nuclei. (britannica.com)
- At UC Davis, cell biology majors enjoy access to extensive laboratory resources and research opportunities, meaning you can be at the forefront of exciting new frontiers in research in genetics, disease processes and developmental biology. (ucdavis.edu)
- At the upper division level, you will study more advanced topics in organic and physical chemistry and developmental, molecular and cell biology. (ucdavis.edu)
- The Cell and Developmental Biology Research Group is focused on understanding how cellular and molecular processes combine to regulate the development and functioning of animals and plants. (bath.ac.uk)
- Diverse in vivo and cell culture models are employed to address fundamental questions relevant to crop improvement, human health and ageing (especially neurodegenerative disorders, cancer and diabetes), and developmental biology, stem cells and regenerative medicine. (bath.ac.uk)
- The Cell and Developmental Biology Center aims to understand the molecules and the molecular interactions inside cells that build the organelle systems that support basic and specialized functions to control cell fate and behavior. (nih.gov)
- This Center also seeks to apply its basic cell and developmental biological research to the understanding and treatment of human diseases. (nih.gov)
- Imaging of inter- and intracellular events range from the nanometre scale of molecular and ultrastructural investigations to the millimetre level required for developmental biology. (zeiss.com)
- Cell polarity is the simplest form of whole-cell pattern beyond spherical symmetry, from which more complex developmental and multicellular patterns emerge. (jhmi.edu)
- Developmental Cell 42. (ucl.ac.uk)
- This course is intended for research scientists and PhD students who already have laboratory experience and a good knowledge (equivalent to a Master level) in developmental and cell biology. (pasteur.fr)
- Harland is a pioneer in the field of developmental biology whose major contributions to the field include understanding dorsal ventral patterning of the early embryo and the induction and patterning of the neural plate. (berkeley.edu)
Living organisms5
- [7] [8] Cell theory , first developed in 1839 by Matthias Jakob Schleiden and Theodor Schwann , states that all organisms are composed of one or more cells, that cells are the fundamental unit of structure and function in all living organisms, and that all cells come from pre-existing cells. (wikipedia.org)
- The cell is the fundamental unit of all living organisms. (eurekalert.org)
- All living organisms, with the exception of viruses (and there is debate whether or not they can be considered living organisms), consist of cells, demonstrating the unity, harmony, and interconnectedness of life. (newworldencyclopedia.org)
- Robert Hooke was the first person to term the building block of all living organisms as "cells" after looking at cork . (wikipedia.org)
- In 1665, Robert Hooke termed the building block of all living organisms as "cells" after looking at a piece of cork and observing a cell-like structure, however, the cells were dead and gave no indication to the actual overall components of a cell. (wikipedia.org)
Cytology4
- The study of cells is called cell biology , cellular biology, or cytology. (wikipedia.org)
- Cytology Cytology is the branch of biology that studies cells, the building blocks of life. (bookrags.com)
- Cell biology (also called cytology , from the Greek κυτος, kytos , "vessel") is a branch of biology that studies the structure and function of the cell , which is the basic unit of life . (wikipedia.org)
- Cell biology (also cellular biology or cytology) is a branch of biology studying the structure and function of the cell, also known as the basic unit of life. (wikipedia.org)
Differentiation9
- In a study funded by a NASA Space Biology grant researchers sent cultures of mouse embryonic stem cells into low earth orbit for 15 days on the STS-131 mission to follow the progress of stem cell differentiation, both while in space and then in culture back in normal gravity on earth. (nasa.gov)
- p21 stimulates and regulates cellular differentiation in stem cells. (nasa.gov)
- Cell culture imaging can provide information on growth, contamination, cell differentiation and status, and transfection rates. (zeiss.com)
- Mast cells, like blood cells, are derived from pluripotent bone marrow hematopoietic stem cells but, unlike blood cells, they leave the bone marrow as progenitors and migrate into virtually all vascularized tissues to complete their differentiation under the influence of factors present at each tissue site. (hindawi.com)
- We found that myocilin is expressed in bone marrow-derived mesenchymal stem cells (MSCs) and affects their differentiation into osteoblasts. (nih.gov)
- Our lab is currently focused on (1) identifying optimal conditions for differentiation of engineered human B cells into long-lived antibody-secreting cells, (2) assessing the impact of autophagy on plasma cell survival, and (3) determining the effect that a host immune system will have on engrafted engineered B cells. (seattlechildrens.org)
- Steroids and related hormones, including those derived from vitamins A and D3, are often thought to induce cellular differentiation and are frequently associated with an inhibition of cell growth. (the-scientist.com)
- Simplistically, cell growth and differentiation are thought of as opposing phenomena, and frequently, a terminally differentiated cell is also a post-mitotic cell. (the-scientist.com)
- Cells have to withstand stress from changing environmental conditions, such as temperature, pH, nutrient or oxygen supply, but also during cell differentiation and aging. (uni-due.de)
Protein19
- Interactions create most behaviors around us: A meeting between two people, file transfers among computers, predator-prey dynamics, cell responses, complex protein formation or DNA-protein binding. (springer.com)
- This energy can be used for cellular activities including muscle cell contraction, cell division, protein synthesis and transmission of nerve impulses. (google.com)
- Using these methods, we can now easily readily study protein fatty acylation in cells and even i n vivo (33). (ualberta.ca)
- Protein transport into the outer segment is influenced by the light:dark cycle, and we propose that formation of outer segment disks is affected by the ability of the cell to respond to light. (ualberta.ca)
- The primary research interest of the Laboratory of Cellular Physiology, led by Dr. Lois Greene, is in the formation and breakdown of normal and pathological protein complexes in the cell, with an emphasis on the role of molecular chaperones. (nih.gov)
- Space Biology researchers are looking at how the protein p21 can be used to stimulate bone growth. (nasa.gov)
- It is well known that during antigen recognition, T cells can create stable protein clusters which are large enough to be seen even with classical fluorescence microscopy. (eurekalert.org)
- Tiny nanoscopic protein clusters were considered to be precursors of these larger structures - with great importance for the function of T cells. (eurekalert.org)
- neurodegenerative diseases (Alzheimer's, Parkinson's and prion diseases), often caused by an "infectious" protein that forms aggregates on brain cells and leads to malfunction or progressive loss of neurons. (pasteur.fr)
- In animal cells, Taxol disrupts microtubule formation by binding to microtubules and accelerating their assembly from the protein precursor, tubulin. (google.com)
- The Department is devoted to cutting-edge research that addresses basic questions in biology, including the control of gene expression, cell fate determination, protein synthesis, the genetics of behavior, control of the cell cycle, and signaling pathways within the cell. (brown.edu)
- and to track any and every protein in action within the cell. (i-sis.org.uk)
- Antibody secreting plasma cells are dedicated protein-producing machines that are responsible for neutralizing viruses and bacteria, but also can cause disease. (seattlechildrens.org)
- One focus of the lab is to leverage this technology to build a cell therapy for protein delivery. (seattlechildrens.org)
- First, these cells can produce protein indefinitely. (seattlechildrens.org)
- Second, antibody-secreting B cells produce similar quantities of protein as industrial cell lines. (seattlechildrens.org)
- This new volume of Methods in Cell Biology looks at micropatterning in cell biology and includes chapters on protein photo-patterning on PEG with benzophenone, laser-directed cell printing and dip pen nanolithography. (elsevier.com)
- The molecular mechanisms responsible for the signalling and biochemical responses of cells with a particular focus on protein structure and function. (massey.ac.nz)
- The course explores current methods of protein analysis, advanced studies in protein structure and function, cell signalling and cellular processes. (massey.ac.nz)
Eukaryotic cell4
- This module takes students on a journey through the eukaryotic cell. (bangor.ac.uk)
- Demonstrate a conceptual understanding of how the different organelles and compartments form a living eukaryotic cell. (bangor.ac.uk)
- Demonstrate a conceptual understanding of how the different organelles and compartments interact within a living eukaryotic cell. (bangor.ac.uk)
- With spatial and temporal activation of multiple switches factored in, it is not surprising to find Rho GTPases having such a prominent role in eukaryotic cell biology. (nih.gov)
Membranes2
- Topics to be discussed include the cell surface and membranes, cytoskeletal elements and motility, cytoplasmic organelles and bioenergetics, the interphase nucleus and chromosomes, mitosis, meiosis, and cell cycle regulation. (amherst.edu)
- Viruses lack common characteristics of a living cell, such as membranes, cell organelles , and the ability to reproduce by themselves. (wikipedia.org)
Immunology4
- That the millions of users of nature.com can now sign up for an e-mail copy of the table of contents for the Immunology & Cell Biology issue in which your article is published. (nature.com)
- That an academic journal like Immunology & Cell Biology hosted on nature.com has on average over 50,000 page views on their web site per month. (nature.com)
- Immunology & Cell Biology has adopted Springer Nature's online submission system, which allows authors to submit papers via the Web. (nature.com)
- Many studies involve the Department of Genomes & Genetics , to develop the genomics side, or the Department of Immunology , to study immune response in cells. (pasteur.fr)
Cellular biology3
- Cellular biology encompasses a vast field, from the unicellular to complete living systems. (zeiss.com)
- Cytoplasm Cellular Biology Cells are the structural units of all living things (with the possible exceptions of viruses and prions). (einet.net)
- The research programs of the Core Faculty in CCMB lie fundamentally at the intersection of computer science, evolutionary biology, mathematics, and molecular and cellular biology. (brown.edu)
20201
- Corning Incorporated will showcase its life sciences solutions April 14 - April 17 at Chinese Society for Cell Biology 2020 Meeting in Suzhou, China. (corning.com)
Biological23
- The cell (from Latin cella , meaning "small room" [1] ) is the basic structural, functional, and biological unit of all known organisms . (wikipedia.org)
- Prokaryotic cells were the first form of life on Earth, characterized by having vital biological processes including cell signaling . (wikipedia.org)
- With those stimuli, the molecules in the liquid crystal coating aligned in whatever direction Greta wanted, creating surface patterns that particles or biological cells could adhere to and grow on. (nist.gov)
- Originally used to prove the existence of biological cells, the microscope has long been recognized for its important role in biological research. (nist.gov)
- Cell Research is published in partnership with the Shanghai Institutes for Biological Sciences (SIBS), and Chinese Academy of Sciences (CAS). (springer.com)
- Cell biology is the discipline of biological sciences that studies the structure, physiology, growth, reproduction and death of cells. (nature.com)
- Enzymes function as biological catalysts and are made by all living cells. (google.com)
- Cell biology majors find their study provides an excellent background for entering graduate or professional schools in biological or health sciences. (ucdavis.edu)
- The Bioculture System is a space biological science incubator designed to conduct cell and microbiology research on the ISS. (nasa.gov)
- The Major and Liberal programs offer decreasing levels of specialization in Anatomy and Cell Biology but with a broader base in other biological sciences. (mcgill.ca)
- Hence, in order to understand essential biological processes and the perturbations that give rise to disease, one must first dissect the functions of cells and the mechanisms that regulate them. (eurekalert.org)
- In the present work a validation of a protocol for isolation, culture, expansion, freezing, and thawing of olfactory mucosa mesenchymal stem/stromal cells was performed, applied to the rat model, as well as a biological characterization of these cells. (hindawi.com)
- cancers: the aim being to study the biological processes that explain both the normal process of cell division and migration, until the mechanisms behind cancer proliferation, cancers invading cells and their metastasis in the organism are understood. (pasteur.fr)
- Research into all these biological phenomena in cells requires state-of-the-art microscopy and high-level human expertise to analyze the findings. (pasteur.fr)
- Besides the roles in pathological conditions, the biological functions of mast cells include roles in innate immunity, involvement in host defense mechanisms against parasites, immunomodulation of the immune system, tissue repair, and angiogenesis. (hindawi.com)
- This paper presents evidence that lipid rafts or raft components modulate many of the biological processes in mast cells, such as degranulation and endocytosis, play a role in mast cell development and recruitment, and contribute to the overall preservation of mast cell structure and organization. (hindawi.com)
- Tissue Types Histology is the branch of biological science concerned with the study of cells and the extracellular matix of animal and plant tissues. (einet.net)
- Chemistry concepts necessary for understanding biological processes are introduced, as well as the structure and function of cell components. (studiesabroad.com)
- Sections dealing with genetics and cell division provide an introduction to biological diversity. (studiesabroad.com)
- One of the current grand challenges in biology is bridging the gap between detailed gene/interaction lists and phenotypic, systems-level behaviors of biological networks. (ucl.ac.uk)
- Centrifugal Separations in Molecular and Cell Biology focuses on the application of modern centrifugation technology in molecular and cell biology, including the separation and fractionation of biological particles by centrifugation on the preparative and analytical scales. (elsevier.com)
- The Center for Computational Molecular Biology (CCMB) promotes the development, implementation and application of analytical and computational methods to foundational questions in the biological and medical sciences. (brown.edu)
- Knowing the components of cells and how cells work is fundamental to all biological sciences while also being essential for research in biomedical fields such as cancer, and other diseases. (wikipedia.org)
Proliferation4
- Temporal and time-lapse fluorescence imaging of live cells offers insights into intracellular and molecular dynamics, cell proliferation, cell motility and many other aspects. (zeiss.com)
- Olfactory mucosa mesenchymal stem/stromal cells have been regarded as a promising tool in regenerative therapies because of their several favorable properties such as multipotency, high proliferation rate, helpful location, and few associated ethical issues. (hindawi.com)
- We discovered that myocilin increased cell proliferation and survival. (nih.gov)
- There is a dearth of new ideas that can lift cell biology out of the pervasive molecular malaise that has infected all of the life sciences to varying degrees in this post-genomics era: a proliferation of molecular hardware and data, with no modicum of general understanding on the horizon. (i-sis.org.uk)
Molecules9
- The importance of diffusion in cells as the movement of molecules along a concentration gradient. (google.com)
- Research in molecular biology has so advanced the number of known matrix molecules and the topic of gene structure and regulation that we won- dered how best to incorporate the new material. (springer.com)
- However, light can react with intracellular molecules or fluorophores to produce free radicals, and long-term imaging of cells may result in phototoxicity. (zeiss.com)
- In particular, single-cell RNA sequencing (scRNA-seq) permits one to determine the levels of RNA molecules - the gene copies - that are expressed in a given cell, and several versions of the methodology have been described in recent years. (eurekalert.org)
- The purpose of scRNA-seq is to identify the relative amounts of the messenger RNA (mRNA) molecules present in the cells of interest. (eurekalert.org)
- The central theme of the Department of Molecular Cell Biology is how molecules by dynamical organisation and interaction create life. (vu.nl)
- The functioning of a cell depends upon its ability to extract and use chemical energy stored in organic molecules. (newworldencyclopedia.org)
- however, most of the processes within the cell are made up of a mixture of small organic molecules, inorganic ions, hormones, and water. (wikipedia.org)
- [12] These molecules within the cell, which operate as substrates, provide a suitable environment for the cell to carry out metabolic reactions and signalling. (wikipedia.org)
Cytoskeleton1
- We work with a protozoan parasite Trypanosoma brucei to better understand their role in the architecture of the cytoskeleton, cell division and cytokinesis. (brookes.ac.uk)
Physiology5
- ANATOMY, PHYSIOLOGY & CELL BIOLOGY Emphasizes programs with a strong correlation between structure and function. (ucdavis.edu)
- ANATOMY, PHYSIOLOGY & CELL BIOLOGY We work to advance the knowledge and techniques of cellular and physiological mechanisms of organ function. (ucdavis.edu)
- Cell motility is crucial for the development and physiology of diverse cell types and tissues, yet mechanistic insights have come mainly from transformed cell lines moving on 2D surfaces. (jhmi.edu)
- [7] Modern day cell biology research looks at different ways to culture and manipulate cells outside of a living body to further research in human anatomy and physiology, to derive treatments and other medications, etc. (wikipedia.org)
- The Department of Cell Biology offers graduate training in cell biology and physiology leading to the Ph.D. degree. (gradschools.com)
20181
- If you started this programme in 2018, you can find information about 2018 entry on the 2018 Cell Biology page . (st-andrews.ac.uk)
Tissues9
- Erom these interactions large-scale systems emerge as a mesh of relations: Society, Internet, food webs, organisms, tissues or cells. (springer.com)
- This Center studies how cell behavior guides normal development, including the creation and maintenance of tissues and organs. (nih.gov)
- The process of directed cellular movement is of critical importance to human health, as is observed when immune cells seek out infected tissues or metastatic cancer cells invade new organs. (nih.gov)
- Embryonic stem cells can differentiate into all the specialized cells needed to grow a whole organism but are also responsible for maintaining the normal turnover of regenerative organs, such as blood, skin, or intestinal tissues. (nasa.gov)
- Stem/stromal cell-based therapies are a branch of regenerative medicine and stand as an attractive option to promote the repair of damaged or dysfunctional tissues and organs. (hindawi.com)
- The scientists in this research department want to shed light on normal and pathological cell function and the interactions between infectious agents and their hosts (humans), both by unraveling the mechanisms governing them but also by understanding the consequences of these interactions on tissues, organs and the entire organism. (pasteur.fr)
- We have extensive experience in all aspects of single cell transcriptomics and continue to generate large amounts of data (see Figure) from a wide variety of mouse and human normal and diseased tissues. (jax.org)
- We are also implementing imaging mass cytometry approaches to provide some spatial context to cell-types within tissues. (jax.org)
- The course includes modules that emphasise structure and function in the cells of animals, plants, and microbes, in addition to how cells interact as they form tissues and embryos. (st-andrews.ac.uk)
Mechanisms7
- Our lab studies the mechanisms underlying formation of an outer segment during development and its ongoing maintenance in the adult, with the goal of expanding out understanding of the cell biology underlying retinal dystrophies. (ualberta.ca)
- This research often coincides with studies on cell senescence and the mechanisms of aging. (pasteur.fr)
- The basic cellular and molecular mechanisms underlying the production and function of blood cells. (nih.gov)
- The Hematopoiesis and Hematopoietic Stem Cell Biology program focuses on understanding the basic cellular and molecular mechanisms underlying the production and function of blood cells in health and disease. (nih.gov)
- Major areas of interest include the basic mechanisms involved in regulating the production and terminal development of blood cells, referred to as hematopoiesis. (nih.gov)
- With a focus on the regulation of cell polarity, identity and signaling we are studying plant germline development and function, fertilization mechanisms and early seed development. (uni-regensburg.de)
- Eukaryotic cells have evolved to use distinct cellular compartments, known as organelles, which maintain homeostatic mechanisms to ensure their distinct functionalities and overall cellular homeostasis. (uni-due.de)
Nucleus9
- Gurdon used a technique known as somatic cell nuclear transfer (SCNT), in which the nucleus of a somatic cell is transferred into the cytoplasm of an enucleated egg (an egg that has had its nucleus removed). (britannica.com)
- Here, we have found that Klotho is enriched in nucleus pulposus (NP) cells and Klotho overexpression attenuates H 2 O 2 -induced acute inflammation essentially via suppressing Toll-like receptor 4 (TLR4). (hindawi.com)
- Measurements of the amount of DNA per nucleus were taken on a large number of cells from a growing fungus. (google.com)
- In which stage of the cell cycle did the nucleus contain 6 picograms of DNA? (google.com)
- A group of cells is assayed for DNA content immediately following mitosis and is found to have an average of 8 picograms of DNA per nucleus. (google.com)
- The Cell Nucleus Structure/function correlations The cell nucleus is a remarkable organelle because it forms the package for our genes and their controlling factors. (einet.net)
- [10] Prokaryotic cells, lacking an enclosed nucleus, include bacteria and archaea . (wikipedia.org)
- Cells are of two types: eukaryotic, which contain a nucleus, and prokaryotic, which do not. (wikipedia.org)
- Most important among these is a cell nucleus, an organelle that houses the cell's DNA. (wikipedia.org)
Laboratory8
- The Laboratory of Cell and Tissue Morphodynamics, led by Dr. Clare Waterman, has made pioneering discoveries into the complex and dynamic mechanical interactions between organelle systems within cells that are required for directed movement. (nih.gov)
- The Laboratory of Cell Biology is led by Dr. Edward Korn, who has been studying the function and regulation of the actomyosin system in its diverse forms since he discovered the first unconventional non-filamentous myosin, myosin I (containing only a single heavy chain), in the single-cell soil protozoan Acanthamoeba castellanii , approximately forty years ago. (nih.gov)
- The Single Cell Biology Laboratory (SCBL) develops and offers single cell capabilities to JAX faculty and, through a Single Cell Genomics Center agreement, University of Connecticut faculty. (jax.org)
- Read a description of the Laboratory of Cell and Molecular Biology . (nih.gov)
- Sidney Frank Hall of Life Sciences is a five-story, 169,000-square-foot glass and brick structure devoted to the study of human biology and the Laboratory of Molecular Medicine that houses laboratories of faculty drawn from five basic science departments of the Brown Medical School, and two cutting edge research centers. (brown.edu)
- The laboratory of Cell Biology studies the dynamics of cellular organization in relation to cell growth, cell division and the organization of cell walls. (wur.nl)
- Researchers from the laboratory of Cell Biology publish in Cell in collaboration with groups in Dresden en Amsterdam. (wur.nl)
- 1 MRC Laboratory for Molecular Cell Biology and Cell Biology Unit, Cancer Research UK Oncogene and Signal Transduction Group, University College London, Gower Street, London WC1E 6BT, UK. (nih.gov)
Metabolism2
- It presents developments in cell birth, lineage and death, expanded coverage of signaling systems and of metabolism and movement of lipids. (worldcat.org)
- Mitochondria change their morphology and distribution depending on the metabolism and functional state of a cell. (hindawi.com)
Structural Biology1
- Laboratories for Molecular Medicine (LMM) houses the other half of MCB labs along with the Genomics Core Facility, Structural Biology Core Facility, & the Transgenic Mouse Facility. (brown.edu)
Pathways5
- Subjects under elucidation range from the structural dynamics of domains within macromolecules and subunits of macromolecular assemblies, through the integration of pathways and organelles, to the interactions of a cell with its immediate environment. (vu.nl)
- We are currently investigating how aneuploidy affects the epigenetic state of cells and which cellular pathways may be particularly sensitive to modification by an unbalanced chromosome dosage. (jhmi.edu)
- Rho GTPases are molecular switches that control a wide variety of signal transduction pathways in all eukaryotic cells. (nih.gov)
- [1] Cell biology is concerned with the physiological properties, metabolic processes, signaling pathways , life cycle , chemical composition and interactions of the cell with their environment. (wikipedia.org)
- Cell biology focuses more on the study of eukaryotic cells, and their signalling pathways, rather than on prokaryotes which is covered under microbiology . (wikipedia.org)
Bacteria8
- [3] Organisms can be classified as unicellular (consisting of a single cell such as bacteria ) or multicellular (including plants and animals ). (wikipedia.org)
- The cell wall consists of peptidoglycan in bacteria, and acts as an additional barrier against exterior forces. (wikipedia.org)
- Did you know there are about 10 trillion human cells in our body, and another 90 trillion bacteria cells on and in your body! (google.com)
- using examples from typical plant , animal , fungi and bacteria cells. (google.com)
- Offered as BIOL 291 and BCBP 291) An analysis of the structure and function of cells in plants, animals, and bacteria. (amherst.edu)
- Also includes information about human cells, viruses, bacteria, and crystals as well as tips on cell imaging and research. (einet.net)
- In the case of eukaryotic cells - which are made up of animal, plant, fungi, and protozoa cells - the shapes are generally round and spherical or oval [10] while for prokaryotic cells - which are composed of bacteria and archaea - the shapes are: spherical ( cocci ), rods ( bacillus ), curved ( vibrio ), and spirals ( spirochetes ) . (wikipedia.org)
- Bacteria can be classed as either gram positive or gram negative depending on the cell wall composition. (wikipedia.org)
Gene10
- WetLab-2 will enable traditional uses of quantitative PCR, such as measuring gene transcription or rapid detection of gene targets that indicate infectious disease, cell stress, changes in cell cycle, growth and development, and/or genetic abnormality. (nasa.gov)
- One of the questions that may be answered from this work is whether mice missing the p21 gene will induce stem cells to reproduce in microgravity aboard the ISS. (nasa.gov)
- Furthermore, aberrant patterns of gene activity point to disturbances in gene expression and cell function, and reveal the presence of specific pathologies. (eurekalert.org)
- It aims to provide no less than a complete inventory of all the cell types and subtypes in the human body at all stages of development from embryo to adult on the basis of their patterns of gene activity. (eurekalert.org)
- Our recent work has demonstrated dramatic ways in which aneuploidy alters gene expression and cell behavior. (jhmi.edu)
- CellView is a web application that allows easy and intuitive exploration of gene expression to validate clustering, describe heterogeneity, and identify and discover new cell types in complex single cell transcriptome data sets. (jax.org)
- Historically, gene delivery to B cells has been challenging. (seattlechildrens.org)
- We recently developed an efficient method for gene delivery to primary human B cells. (seattlechildrens.org)
- Jun-Fos and receptors for vitamins A and D recognize a common response element in the human osteocalcin gene," Cell, 61:497-504, 1990. (the-scientist.com)
- This finding "uncovers the physical parameters that affect gene activation, thus pushing forward our understanding of how genes are regulated in time and space," according to NYU Biology Professor Christine Rushlow. (berkeley.edu)
Mitosis3
- If cells in the process of dividing are subjected to colchicine, a drug that interferes with the formation of the spindle apparatus, at which stage will mitosis be arrested? (google.com)
- Where do the microtubules of the spindle originate during mitosis in both plant and animal cells? (google.com)
- Reproduction by cell division (binary fission, mitosis or meiosis ). (newworldencyclopedia.org)
Anatomy3
- These programs also form a sound background for graduate studies in Anatomy and Cell Biology, or for further professional training. (mcgill.ca)
- in Anatomy and Cell Biology provides an excellent preparation for technical and administrative positions in laboratories of universities, research institutions, hospitals, pharmaceutical, and biotechnological industries. (mcgill.ca)
- Inquiries about programs should be directed to the Department of Anatomy and Cell Biology. (mcgill.ca)
Microscopic5
- Research in cell biology uses microscopic and molecular tools and examines all cell types, from unicellular organisms such as protozoa to the specialised cells that consitutute multicellular organisms. (nature.com)
- Quicktime videos of time-lapse microscopic views of cells from publications in the "Journal Of Cell Biology. (merlot.org)
- Maintaining a healthy and stable cell culture requires daily microscopic examination, which should be quick and easy in order to prevent environmental stress and minimise the risk of contamination, as well as to keep your work load low. (zeiss.com)
- This is done both on a microscopic and molecular level as it encompasses prokaryotic cells and eukaryotic cells . (wikipedia.org)
- Advancement in microscopic techniques and technology such as fluorescence microscopy , phase-contrast microscopy , dark field microscopy , confocal microscopy , cytometry , transmission electron microscopy , etc. have allowed scientists to get a better idea of the structure of cells. (wikipedia.org)
Regenerative medicine1
- The purpose of Stem Cell Reviews and Reports is to cover contemporary and emerging areas in stem cell research and regenerative medicine. (springer.com)
Biologists5
- ASCB is an inclusive, international community of biologists studying the cell, the fundamental unit of life. (idealist.org)
- Cell biologists study these processes and the principles that govern the organization and function of cells within the body. (ucdavis.edu)
- The Honours program is designed as the first phase in the training of career cell and molecular biologists. (mcgill.ca)
- Cell and Molecular Biology Online, an informational resource for cell and molecular biologists. (einet.net)
- We have also developed methods to enable biologists to interact and mine single cell transcriptome data, specifically the CellView app developed by Mohan Bolisetty within the group. (jax.org)
Chemistry1
- biology, chemistry, biotechnology engineering and mass spectrometry. (weizmann.ac.il)
Fundamental8
- Cells-the basic unit of organization of all life-carry out the fundamental processes necessary for organisms to grow, reproduce and negotiate their environments. (ucdavis.edu)
- Applications range from fundamental biology investigations to commercial drug discovery efforts. (nasa.gov)
- Presents an introduction to the fundamental concepts of cell biology. (worldcat.org)
- Movement of and within cells is fundamental to life, whether in development of an organism, defense against infection, repair after injury, or in pathologies such as cancer and heart disease. (nih.gov)
- However, Cell Biology is fundamental to all of biology, and can serve as a reasonable starting point for students exploring the field. (wikiversity.org)
- You might want to write a lesson about how the regulation of cell survival is a fundamental process that helps control the number of cells in a tissue. (wikiversity.org)
- For example, scRNA-seq is a fundamental prerequisite for the success of the effort to assemble a Human Cell Atlas - one of the most ambitious international projects in genomics since the initial sequencing of the human genome. (eurekalert.org)
- On March 23, during the 41st Annual Meeting & Exhibition of the American Association for Dental Research (AADR), held in conjunction with the 36th Annual Meeting of the Canadian Association for Dental Research, a symposium titled "TMJ: Stem Cell Biology and Engineering toward Clinical Translation" will provide a rare forum for multidisciplinary discussion of the biology, engineering and clinical translation of fundamental discoveries towards novel clinical therapy. (redorbit.com)
Researchers9
- Researchers who work with stem cells have ambitious goals. (nist.gov)
- Researchers also often use toxic dyes for labeling live and dead cells. (nist.gov)
- Researchers at NIST have devised a way to eliminate a long-standing problem affecting our understanding of both living cells and batteries. (nist.gov)
- Since the initial development of iPS cells, researchers have been working to improve the techniques and to learn what drives pluripotent stem cells to differentiate in particular ways. (britannica.com)
- The Bio-Chip Space-Lab provides an accessible platform that enables academic and industry researchers to perform long-term automated cell culturing experiments with live-cell imaging in the unique microgravity environment onboard the International Space Station. (nasa.gov)
- Cell and Molecular Space Biology Researchers conduct experiments that help develop an understanding of the ways cells (or parts of cells) function and respond to spaceflight. (nasa.gov)
- Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich have now carried out a comprehensive comparison of methodologies that quantify RNAs of single cells. (eurekalert.org)
- International Journal of Cell Biology maintains an Editorial Board of practicing researchers from around the world, to ensure manuscripts are handled by editors who are experts in the field of study. (hindawi.com)
- Cell Signalling Biology provides researchers teachers and students alike with an outstanding online resource describing the biology of cell signalling. (portlandpress.com)
Signal transduction1
- Simply put, signal transduction is the movement of a signal from outside to inside the cell. (ualberta.ca)
Study of eukaryotic cells1
- The study of eukaryotic cells is typically the main focus of cytologists, whereas prokaryotic cells are the focus of microbiologists. (wikipedia.org)
Mitochondria3
- Here, we analyzed the mitochondria and selected structures in female germ-line cysts in a representative of clitellate annelids - the white worm Enchytraeus albidus in which each germ cell has one cytoplasmic bridge that connects it to a common cytoplasmic mass. (hindawi.com)
- A thorough understanding of molecular cell biology research will be obtained, focusing on mitochondria and the secretory pathway. (rug.nl)
- Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output" References: https://www.cell.com/cell/fulltext/S0092-8674(20)31000-X. (brandeis.edu)
Microscopy10
- Therefore, live-cell imaging often requires the multi-dimensional capabilities of confocal laser scanning microscopy (CLSM). (zeiss.com)
- Using serial block-face scanning electron microscopy (SBEM), we prepared three-dimensional ultrastructural reconstructions of the entire selected compartments of a cyst at the advanced stage of oogenesis, i.e. the nurse cell, cytophore, and cytoplasmic bridges of all 16 cells (15 nurse cells and oocyte). (hindawi.com)
- Various microscopy approaches used in current molecular cell biology research will be discussed. (rug.nl)
- Research in our department employs a range of cross-disciplinary approaches, including state of the art optical tools for confocal and electron microscopy, physical technologies such as X-ray diffraction, and innovative techniques in molecular biology. (brown.edu)
- Bio-Formats reads proprietary microscopy image data and metadata, and converts them to OME-TIFF, a combination of TIFF and OME-XML . (dcc.ac.uk)
- [3] Electron microscopy gives a much higher resolution showing greatly detailed cell structure. (wikipedia.org)
- The study of cells is performed using several techniques such as cell culture, various types of microscopy, and cell fractionation. (wikipedia.org)
- Due to advancements in microscopy, techniques and technology have allowed for scientists to hold a better understanding of the structure and function of cells. (wikipedia.org)
- Fluorescence microscopy: Fluorescent markers such as GFP, are used to label a specific component of the cell. (wikipedia.org)
- Transmission electron microscopy: Involves metal staining and the passing of electrons through the cells, which will be deflected upon interaction with metal. (wikipedia.org)
Research29
- Cells are being used in drug discovery, therapeutics development, biomedical research, and biotechnological and medical applications. (nist.gov)
- Stem Cell Research & Therapy is the major forum for translational research into stem cell therapies. (springer.com)
- The journal Cell and Tissue Biology publishes research on animal and plant cells, in vivo and in cell culture, which offers insight into the structure and functions of the live cell as a whole. (springer.com)
- The main objective of the journal is to provide a competent representation and integration of research made on cells (animal and plant cells, both in vivo and in cell culture) offering insight into the structure and functions of live cells as a whole. (springer.com)
- NIEHS research uses state-of-the-art science and technology to investigate the interplay between environmental exposures, human biology, genetics, and common diseases to help prevent disease and improve human health. (nih.gov)
- Many years of research efforts studying the implications of myristoylation in cancer and apoptosis have led to the discovery that blood cancer cells are extremely vulnerable to myristoylation inhibitors. (ualberta.ca)
- The strong research focus of the major gives you the chance to become familiar with modern experimental biology, and you will be encouraged to work with faculty on independent research products to enhance your classroom studies. (ucdavis.edu)
- This incubator supports a wide diversity of tissue, cell, and microbiological cultures and experiment methods to meet any spaceflight research experiment goals and objectives, including cell biology, microbiology, discovery biology, and drug-testing studies to be conducted on the ISS. (nasa.gov)
- Previous research conducted by Space Biology investigators revealed that the stem cell mechanism that controls bone growth is weakened in microgravity. (nasa.gov)
- As life scientists, the study of cells and live-cell imaging are intrinsic to your research. (zeiss.com)
- Depending on your research interests, cells may derive from an immortalized cell line, primary cells, stem cells or ex vivo tumour cells for cancer cell imaging. (zeiss.com)
- Our research focuses on T cells, which can recognize antigens and therefore play an important role in our immune system. (eurekalert.org)
- International Journal of Cell Biology publishes original research articles as well as review articles in all areas of cell biology. (hindawi.com)
- The goal of our research is to understand how eukaryotic cells polarize, divide, move, and vary their genomes to adapt to the changing environment. (jhmi.edu)
- An emerging line of research in our lab is to study the motility of cells of well-defined tissue origins in mechanical and geometrical environments that mimic physiological conditions. (jhmi.edu)
- Shedding light on the intricate workings of microbes and cells is the focus of research conducted in the Department of Cell Biology & Infection. (pasteur.fr)
- in vitro models to study diseases, particularly microfluidic cell and organ culture models with the Center for Innovation & Technological Research (Citech) . (pasteur.fr)
- Bioreactor expands health research NASA device gives a new dimension to cell science Dec. 18, 1997 Dec. 28, 1997 update: Added hi-res JPG images suitable for printing. (einet.net)
- The pancreatic Islet Cell Biology Core is located on the 12 floor (12-169 to 12-171) of the Smilow Center for Translation Research, 3400 Civic Center Blvd, Philadelphia, PA 19104. (upenn.edu)
- Examples of molecular cell biology research will be discussed from a molecular to cellular level using in vitro and in vivo approaches in yeast and mammalian model systems. (rug.nl)
- The School of Biology conducts world-class, innovative multidisciplinary research, and in the UK Research Excellence Framework 2014 , Biology was ranked second in the UK based on the impact of its research. (st-andrews.ac.uk)
- I met Ling for the first time at the prestigious Gordon Research Conference on Interfacial Water in Cell Biology in Mount Holyoke (Bradley, Massachusetts, USA) in June 2004. (i-sis.org.uk)
- One of two research centers in the US creating libraries of signatures that describe how cells respond to perturbation, it uses the ISA-TAB standard to describe its data. (dcc.ac.uk)
- The center provides advanced instrumentation and expertise for live cell imaging, food sciences and materials research. (wur.nl)
- it is also essential for research in bio-medical fields such as cancer , and other diseases. (wikipedia.org)
- The symposium is co-sponsored by the Craniofacial Biology, Mineralized Tissue and Neuroscience Scientific Research Groups of the International Association for Dental Research. (redorbit.com)
- The graduate program in the Department of Biology provides students with the training they need to excel in academic or biomedical research careers. (gradschools.com)
- The Molecular Biology Program at MU cultivates the use of molecular biology in 24 academic areas of basic research. (gradschools.com)
- These have allowed for and are currently being used for discoveries and research pertaining to how cells function, ultimately giving insight into understanding larger organisms. (wikipedia.org)
Journal of Cell Biology1
- A repository for viewing and analysing multi-dimensional image data associated with articles published in The Journal of Cell Biology. (dcc.ac.uk)
Cycle2
- There are interactive units on the cell cycle, tumor suppressors, proto-oncogenes and their role in the development of cancer. (merlot.org)
- E) the S phase of the cell cycle. (google.com)
Polarity3
- Our ongoing work attempts to explain how molecular components of distinct functional modules interact in time and space to establish cell polarity that is robust to noise but sensitive to physiological inputs. (jhmi.edu)
- A functional consequence of cell polarity in the unicellular organism, the budding yeast, is asymmetric segregation of aging determinants such that cell division generates a young cell with renewed replicative potential from an aged mother cell. (jhmi.edu)
- Parameter-space topology of models for cell polarity. (ucl.ac.uk)
Organism5
- Five years ago, scientists created a single-celled synthetic organism that, with only 473 genes, was the simplest living cell ever known. (nist.gov)
- grow transformed cells to produce a GM organism . (google.com)
- Particular attention is given to genetic and epigenetic programming, cell signalling and whole organism biology. (bath.ac.uk)
- E) Binary fission would not allow the organism to have complex cells. (google.com)
- all vital functions of an organism occur within cells, and cells contain the hereditary information necessary for regulating cell functions and for transmitting information to the next generation of cells. (newworldencyclopedia.org)
Department of Biology1
- The Department of Biology will provide you with the opportunity to learn in new, spacious and modern teaching laboratories which provide excellent facilities for practicals and small group project work, alongside our state-of-the-art computing facilities. (york.ac.uk)
Tissue4
- Scientists can combine cells and the scaffolds they grow on into structures that can repair or restore damaged or lost tissue or organs in patients. (nist.gov)
- These results may provide important clues to the basis for the inhibition of tissue regeneration in space and explain why bone and muscle cell numbers are reduced after long exposures to microgravity. (nasa.gov)
- We isolate primary cells from genetically modified animals and then apply high-resolution biophysical techniques to observe and parameterize their motility in vitro in engineered environments that provide tissue-mimetic tests of environmental inputs. (jhmi.edu)
- This was ultimately concluded by plant scientist, Matthias Schleiden and animal scientist, Theodor Schwann in 1838, who viewed live cells in plant and animal tissue, respectively. (wikipedia.org)
Bioscience1
- The upcoming BioScience-4 mission will be the first study to investigate the division of nervous system stem cells in spaceflight. (nasa.gov)
Genetics and molecular biology1
- Plant Cell Reports publishes original, peer-reviewed articles on new advances in all aspects of plant cell science, plant genetics and molecular biology. (springer.com)
Smaller than eukaryotic cells1
- Prokaryotic cells are much smaller than eukaryotic cells, making prokaryotic cells the smallest form of life. (wikipedia.org)
Cancer cell biology1
- Cancer Cell International publishes articles on all aspects of cancer cell biology, originating largely from, but not limited to, work using cell culture techniques. (springer.com)
Progenitor3
- Two types of cells will be studied in this experiment: neural stem cells and oligodendrocyte progenitor cells, which are derived from neural stem cells. (nasa.gov)
- Recently, stem/progenitor cells have been identified in TMJ disc and condyle, with potential origin from neural crest cells in development. (redorbit.com)
- Putative TMJ stem/progenitor cells are subjected to local, hormonal and other systemic factors in homeostasis in multiple processes that warrant better elucidation. (redorbit.com)
Prokaryotic and eukaryotic cells1
- An exception is the ribosomes , which are present in both prokaryotic and eukaryotic cells. (newworldencyclopedia.org)
Regulation2
- She is interested in understanding biomechanical regulation of stem cell fate decisions in health and disease. (nature.com)
- Our studies examine DNA function and structure, cellular and molecular changes, phenotypic changes to organisms, as well as the ability of eukaryotic cells to generate and maintain their complex internal cyto-architecture integral to the regulation of both growth and form. (nasa.gov)
Organization5
- Typically, the journal publishes articles on biology of free-living and parasitic protists, which unlike Metazoa, are eukariotic organisms at the cellular level of organization. (springer.com)
- Network biology: Understanding the cell's functional organization. (springer.com)
- We are intrigued about how cells generate patterns through self-organization in response to environmental signals, accomplish division or motility through coordinated structural rearrangements and force production, and, when challenged with hostile environments or genetic perturbations, evolve innovative solutions to maintain vitality and functionality. (jhmi.edu)
- The specialization of cells in multicellular organisms to form many different organs and bodily systems all integrated into a harmonious, hierarchically arrayed collective, with each component of equal value and essential to the function of the whole, demonstrates a principle and pattern of organization that provides an analogue for systems of higher order, like ecosystems, families, and nations. (newworldencyclopedia.org)
- We focus on the interactions that cytoskeletal filaments, microtubules and actin, have with each other and from there aim to understand the organization and functioning of large-scale cytoskeletal networks that have essential roles in shaping cells. (wur.nl)
Tumor3
- Here, the authors show that constitutive expression of Sna in primary adult Drosophila intestinal tumors drives EMT and dissemination of tumor cells, induces collective cell migration and formation of polyclonal metastases. (nature.com)
- Our ultimate goals are to identify context-dependent design principles in the cytoskeletal machine that drives cell movement and to use this insight to develop cancer-specific therapies against tumor spreading and metastasis. (jhmi.edu)
- We currently are developing circulating tumor cell enrichment, characterization, and model generation strategies. (jax.org)
Content3
- The high-content interrogation of single cells with platforms optimized for the multiparameter characterization of cells in liquid and solid biopsy samples can. (nist.gov)
- With its acclaimed author team, cutting-edge content, and coverage based on landmark experiments, Molecular Cell Biology has earned an impeccable reputation with instructors. (worldcat.org)
- Cytometry: The cells are placed in the machine which uses a beam to scatter the cells based on different aspects and can therefore separate them based on size and content. (wikipedia.org)
Scientists4
- Scientists are reporting that they have made a living cell from DNA that was originally synthesized in a lab. (scienceblogs.com)
- Scientists need to grow cells with structures like the frames (or scaffolds) that you might see around buildings under construction. (nist.gov)
- In common practices for counting cells, scientists examine samples of cells that float freely and unattached in a liquid, unlike in reality, where they come together into a 3D structure and shape. (nist.gov)
- Scientists have struggled to decide whether viruses are alive or not and whether they are in agreement with the cell theory. (wikipedia.org)
Apoptosis1
- Oppositely, expression of mutated myocilin sensitizes cells to apoptosis induced by oxidative stress. (nih.gov)
Prokaryotes2
- The cells of eukaryotes (left) and prokaryotes (right). (newworldencyclopedia.org)
- Prokaryotes also lack most of the intracellular organelles and structures that are characteristic of eukaryotic cells. (newworldencyclopedia.org)
Genetic1
- Genetic information can be transferred from one cell to another naturally or by genetic engineering . (google.com)
Cytoplasm3
- The DNA of a prokaryotic cell consists of a single circular chromosome that is in direct contact with the cytoplasm . (wikipedia.org)
- Indeed, by the time of Dolly's creation, it was widely accepted that factors in the egg cytoplasm were responsible for reprogramming differentiated cell nuclei. (britannica.com)
- Nonetheless, retroviral delivery remains highly effective, and technical advances to prevent the integration of retroviral material into the nuclear genome have allowed for the generation of iPS cells via ectopic expression (in the cytoplasm) of retrovirus-delivered transcription factors. (britannica.com)
Main1
- This is the main page for the Cell Biology course, in the Department of Cell Biology . (wikiversity.org)
Molecular genetics1
- We strive for integrated analyses on the systems level that combines whole-cell quantitative observation and mathematical modeling with cutting-edge molecular genetics approaches. (jhmi.edu)