A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe and effective in aged patients and in patients with hematologic disorders.
Semisynthetic broad-spectrum cephalosporin.
A group of broad-spectrum antibiotics first isolated from the Mediterranean fungus ACREMONIUM. They contain the beta-lactam moiety thia-azabicyclo-octenecarboxylic acid also called 7-aminocephalosporanic acid.
A semisynthetic cephamycin antibiotic resistant to beta-lactamase.
A semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms. It has a high rate of efficacy in many types of infection and to date no severe side effects have been noted.
Formularies concerned with pharmaceuticals prescribed in hospitals.
Gram-negative bacteria occurring in the lower intestinal tracts of man and other animals. It is the most common species of anaerobic bacteria isolated from human soft tissue infections.
A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
A second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections.
Semisynthetic broad-spectrum cephalosporin with a tetrazolyl moiety that is resistant to beta-lactamase. It has been proposed especially against Pseudomonas infections.
Infections with bacteria of the genus BACTEROIDES.
Semisynthetic wide-spectrum cephalosporin with prolonged action, probably due to beta-lactamase resistance. It is used also as the nafate.
Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).
A semisynthetic cephamycin antibiotic that is administered intravenously or intramuscularly. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative microorganisms.
One of the CEPHALOSPORINS that has a broad spectrum of activity against both gram-positive and gram-negative microorganisms.
Substances that reduce the growth or reproduction of BACTERIA.
Naturally occurring family of beta-lactam cephalosporin-type antibiotics having a 7-methoxy group and possessing marked resistance to the action of beta-lactamases from gram-positive and gram-negative organisms.
Visible accumulations of fluid within or beneath the epidermis.
Non-susceptibility of an organism to the action of the cephalosporins.
Broad- spectrum beta-lactam antibiotic similar in structure to the CEPHALOSPORINS except for the substitution of an oxaazabicyclo moiety for the thiaazabicyclo moiety of certain CEPHALOSPORINS. It has been proposed especially for the meningitides because it passes the blood-brain barrier and for anaerobic infections.
Cyclic AMIDES formed from aminocarboxylic acids by the elimination of water. Lactims are the enol forms of lactams.
Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, GONORRHEA, and HAEMOPHILUS.
One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.
Gram-negative gas-producing rods found in feces of humans and other animals, sewage, soil, water, and dairy products.
Enzymes found in many bacteria which catalyze the hydrolysis of the amide bond in the beta-lactam ring. Well known antibiotics destroyed by these enzymes are penicillins and cephalosporins.
The chemical and physical integrity of a pharmaceutical product.
The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).
A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.
Nonsusceptibility of an organism to the action of penicillins.
A broad-spectrum antibiotic derived from KANAMYCIN. It is reno- and oto-toxic like the other aminoglycoside antibiotics.

In-vitro susceptibilities of species of the Bacteroides fragilis group to newer beta-lactam agents. (1/167)

The in-vitro activities of imipenem and four beta-lactam-beta-lactamase inhibitor combinations were tested against 816 strains of the Bacteroides fragilis group, and compared with other anti-anaerobic agents. None of the strains was resistant to metronidazole, and only one was resistant to chloramphenicol. Mezlocillin and piperacillin were moderately active, while clindamycin was the least active. Rates of resistance varied between various species. The new beta-lactam agents tested showed excellent activity; piperacillin-tazobactam and imipenem were the most active. The emergence of strains that are resistant to these agents, observed in this study, suggests there is a need to perform periodic antimicrobial susceptibility tests.  (+info)

AS-924, a novel bifunctional prodrug of ceftizoxime. (2/167)

To improve the oral absorption of ceftizoxime (CZX), 7beta-[(Z)-2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamido]- 3-cephem-4- carboxylic acid, we synthesized and evaluated a novel series of bifunctional prodrugs, in which L-alanine was introduced into the aminothiazole-oxime moiety at the C-7 position of the various lipophilic esters of CZX. Among these prodrugs, pivaloyloxymethyl 7beta-[(Z)-2-(2-(S)-alanylaminothiazol-4-yl)-2-methoxyiminoa cetamido]-3-cephem-4-carboxylate hydrochloride (ceftizoxime alapivoxil, AS-924) was well absorbed after oral administration in experimental animals and showed potent therapeutic effects in mice infected with gram-positive and gram-negative bacteria.  (+info)

Predicting susceptibility of Streptococcus pneumoniae to ceftriaxone and cefotaxime by cefuroxime and ceftizoxime disk diffusion testing. (3/167)

In this study, disk diffusion testing with ceftizoxime and cefuroxime was evaluated for use in predicting the susceptibility of Streptococcus pneumoniae to ceftriaxone and cefotaxime. Of the 194 isolates included in this study, 138 were susceptible, 34 were intermediate, and 22 were resistant to cefotaxime by MIC testing; 138 isolates were susceptible, 35 were intermediate, and 21 were resistant to ceftriaxone by MIC testing. A zone of inhibition around the cefuroxime disk of >/=32 mm correctly categorized 101 of 138 isolates as susceptible to cefotaxime and ceftriaxone. A zone of inhibition around the ceftizoxime disk of >/=26 mm correctly categorized 111 of 138 isolates as susceptible to cefotaxime and 114 of 138 as susceptible to ceftriaxone. We conclude that disk diffusion can separate S. pneumoniae isolates susceptible to ceftriaxone and cefotaxime from those that are not susceptible. Isolates not falling into the susceptible category by disk diffusion require additional testing to determine the MIC.  (+info)

Gradual alterations in cell wall structure and metabolism in vancomycin-resistant mutants of Staphylococcus aureus. (4/167)

In five vancomycin-resistant laboratory step mutants selected from the highly and homogeneously methicillin-resistant Staphylococcus aureus strain COL (MIC of methicillin, 800 microg/ml; MIC of vancomycin, 1.5 microg/ml), the gradually increasing levels of resistance to vancomycin were accompanied by parallel decreases in the levels of methicillin resistance and abnormalities in cell wall metabolism. The latter included a gradual reduction in the proportion of highly cross-linked muropeptide species in peptidoglycan, down-regulation of the production of penicillin-binding protein 2A (PBP2A) and PBP4, and hypersensitivity to beta-lactam antibiotics each with a relatively selective affinity for the various staphylococcal PBPs; the PBP2-specific inhibitor ceftizoxime was particularly effective.  (+info)

Effect of supplements with lactic acid bacteria and oligofructose on the intestinal microflora during administration of cefpodoxime proxetil. (5/167)

Thirty healthy volunteers in three groups participated in a study of the effect on the intestinal microflora of oral supplementation with Bifidobacterium longum, Lactobacillus acidophilus and oligofructose, an indigestible oligosaccharide, during oral administration of cefpodoxime proxetil bd for 7 days. Those in group A also received an oral supplement with c.1011 cfu of B. longum BB 536 and L. acidophilus NCFB 1748 and 15 g oligofructose daily, those in group B received a supplement with oligofructose only and those in group C received placebo, for 21 days. In all three groups there was a marked decrease in aerobic microorganisms, involving mainly a rapid and almost complete disappearance of Escherichia coli (P: < 0.05) during antimicrobial administration and, thereafter, an overgrowth of enterococci (P: < 0.05). The number of intestinal yeasts also increased significantly (P: < 0.05) in groups A and B over the same period. There was a dramatic decrease in anaerobic microorganisms on day 4 of administration, mainly caused by loss of bifidobacteria (P: < 0.05) in all groups. The number of lactobacilli also decreased but was significantly higher in group A than in group C at the end of cefpodoxime proxetil administration. Clostridium difficile was found in only one person from group A, but six persons each in groups B and C. Of the bifidobacterial strains isolated from the faecal samples in group A, one was similar to the strain of B. longum administered, but most volunteers were colonized by several different strains of B. longum during the investigation period. The administered strain of L. acidophilus was recovered from six patients in group A.  (+info)

Detection of extended-spectrum beta-lactamases in klebsiellae with the Oxoid combination disk method. (6/167)

The Oxoid combination disk method for detecting extended-spectrum beta-lactamases (ESBLs) depends on comparing the inhibition zones of cefpodoxime (10-microg) and cefpodoxime-plus-clavulanate (10- plus 1-microg) disks. The presence of clavulanate enlarged the zones for all of 180 ESBL-producing klebsiellae by >/=5 mm, whereas zones for cefpodoxime-susceptible isolates and cefpodoxime-resistant isolates with AmpC and K1 beta-lactamases were enlarged by +info)

Improved detection of methicillin-resistant Staphylococcus aureus using phenyl mannitol broth containing aztreonam and ceftizoxime. (7/167)

We tested a phenyl mannitol broth containing ceftizoxime and aztreonam (PHMB(+)) for detection of methicillin-resistant Staphylococcus aureus (MRSA) with reference MRSA strains and, subsequently, with clinical samples (n = 1,098). All reference MRSA strains induced color change in PHMB(+) after 24 to 72 h of incubation. In a clinical setting, 40 MRSA strains were detected with PHMB(+), compared with only 23 detected with a routine method. Thus, this selective broth significantly (P < 0.001) improved the rate of MRSA detection.  (+info)

Effect of experimental renal failure on the pharmacodynamics of cefoselis-induced seizures in rats. (8/167)

We investigated the effect of infusion rate and experimental renal failure on the pharmacodynamics of cefoselis (CFSL)-induced seizures. As an animal model of CFSL-induced seizures, male Wistar rats received an intravenous infusion of CFSL at one of three different rates (1.4-5.8 g/h/rat) until the onset of maximal seizures (which occurred after 8.0 to 36.0 min of infusion). Samples of cerebrospinal fluid (CSF), blood (for serum), and brain were obtained immediately after stopping infusion of CSFL. The serum concentration of CFSL at the onset of seizures increased with increasing infusion rate, but brain and CSF concentrations of CFSL at the onset of seizures were not affected by the infusion rate. Ureter-ligated (UL) and control rats received an intravenous infusion of CFSL at 1.4 g/h/rat until the onset of seizures. Then the same procedure as used to determine the effect of infusion rate on the concentrations of CFSL was carried out. Renal failure was associated with a significant decrease in the amount of CFSL required to induce seizures. Serum, brain, and CSF concentrations of CFSL in UL rats were significantly lower than those in control rats. These results indicate that the experimental strategy and animal model in this investigation would be useful to assess the effects of diseases and other variables on the pharmacodynamics of CFSL-induced seizures and that renal failure is one of the risk factors for neurotoxicity of CFSL.  (+info)

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Cefpodoxime proxetil is indicated for the treatment of patients with mild to moderate infections caused by susceptible strains of the designated microorganisms in the conditions listed below.. Recommended dosages, durations of therapy, and applicable patient populations vary among these infections. Please see DOSAGE AND ADMINISTRATION for specific recommendations. Acute otitis media caused by Streptococcus pneumoniae (excluding penicillin-resistant strains), Streptococcus pyogenes, Haemophilus influenzae (including beta-lactamase-producing strains), or Moraxella (Branhamella) catarrhalis (including beta-lactamase-producing strains).. Pharyngitis and/or tonsillitis caused by Streptococcus pyogenes.. NOTE: Only penicillin by the intramuscular route of administration has been shown to be effective in the prophylaxis of rheumatic fever. Cefpodoxime proxetil is generally effective in the eradication of streptococci from the oropharynx. However, data establishing the efficacy of cefpodoxime proxetil ...
Cefpodoxime Proxetil 100 mg per tablet, This is for priced for individual pills Cefpodoxime proxetil is an oral cephalosporin antibiotic used to treat bacterial infections of the skin, such as wounds
TY - JOUR. T1 - Ceftizoxime treatment of pneumonia, cellulitis and other infections in 120 hospitalized patients. AU - Counts, G. W.. AU - Hill, C. D.. AU - Hooton, T. M.. AU - Turck, M.. PY - 1982/1/1. Y1 - 1982/1/1. N2 - Ceftizoxime is a new semisynthetic /Mactamase-resistant parenteral cephalosporin. For most Gram-negative bacilli 1 -0 mg/1 or less of ceftizoxime inhibited 90% of isolates of Gram-negative and Gram-positive bacteria tested by agar dilution. The drug was slightly less active in broth dilution testing, and an inoculum effect was noted in that MIC and MBC were at least two-fold higher when a larger inoculums was employed. Good activity was shown against multi-drug resistant isolates of Serratia marcescens. Ceftizoxime had little activity against isolates of enterococcus and Pseudomonas aeruginosa. In doses of 0-5-1-0 g every 12 h the drug was used to treat pneumonia (71), skin and soft tissue (44), and other infections (5) in hospitalized adult patients. Overall cure rate was 94% ...
The National Medical University named after A.A. Bogomolets, Kiev, Ukraine Purpose: studying the effectiveness, the security profiles and commitment to the therapy using the cefpodoxime proxetil in an acute bronchitis treatment of the bacterial etiology among children in age from 247 years. Patients and methods: there were 32 children under the observation. 18 (56.3%) patients had a clinical bronchitis features simultaneously with the ENT 4diseases or during a day after their occurrence ; the others 14 (43.7%) patients had a febrile fever and a clinical bronchitis features on a 3-5 day of ARVI flowing. The bronchitis treatment and the related diseases performed in accordance with the protocols. Cefpodoxime proxetil (Cefrodox) appointed in the suspension form twice per day during 7 days term.The dynamics rate of the symptoms was performed before the treatment assignment, on 3 and 8 days with an antibiotic therapy. The intensity of intoxication syndrome was studied, the cough frequency and its ...
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Cefpodoxime has a similar spectrum of antibacterial activity to the parenteral cephalosporins ceftriaxone and cefotaxime and a long elimination half-life, which allows once- or twice-daily administration. Cefpodoxime proxetil has proven efficacy in the treatment of community-acquired pneumonia and upper respiratory tract. The clinical efficacy of 5 days of treatment with cefpodoxime proxetil is similar to that of 10 days of treatment with penicillin V. In children with lower respiratory tract infections (primarily pneumonia), clinical and bacteriological efficacy rates achieved with cefpodoxime proxetil treatment were similar to those produced by. Of pleas enrolled, were randomized to cefpodoxime proxetil (8 mg/kg/day desperate daily) and to amoxicilin/clavanulate (amoxicillin 40 mg/kg/day 3 weeks a day).. ...
Dechra Cefpoderm (cefpodoxime proxetil) is a once-a-day cephalosporin antibiotic for the treatment of skin infections, wounds,and abscesses in dogs caused by susceptible strains of Staphylococcus, Streptococcus, Escherichia coli, Pasteurella and Proteus.
Cefpodoxime Proxetil is an extended spectrum, third generation cephalosporin antibiotic. Bactericidal - Arrests the cell wall assembly leading to bacterial cell
Cefpodoxime proxetil belongs to the group of cephalosporin antibiotics. The active ingredient prevents bacteria from building up their cell wall. It is used for the treatment of bacterial infections.
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Cefpodoxime proxetil answers are found in the Johns Hopkins ABX Guide powered by Unbound Medicine. Available for iPhone, iPad, Android, and Web.
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice. ...
Cefpodoxime proxetil answers are found in the Johns Hopkins ABX Guide powered by Unbound Medicine. Available for iPhone, iPad, Android, and Web.
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Cefpodoxime is an oral, third-generation cephalosporin antibiotic. It is active against most Gram-positive and Gram-negative organisms. Notable exceptions include Pseudomonas aeruginosa, Enterococcus, and Bacteroides fragilis. Currently, it is only marketed as generic preparations in the USA, according to the FDA Orange Book. It is commonly used to treat acute otitis media, pharyngitis, sinusitis, and gonorrhea. It also finds use as oral continuation therapy when intravenous cephalosporins (such as ceftriaxone) are no longer necessary for continued treatment.. Zoetis markets cefpodoxime proxetil under the trade name Simplicef for veterinary use. The dose range in dogs is 5-10 mg/kg body weight, administered orally, once a day.. Finecure, India markets the products under trade name Cefpo.. Cefpodoxime inhibits cell wall synthesis by inhibiting the final transpeptidation step of peptidoglycan synthesis in cell walls. It has well established pharmacokinetic profile with absorption of 50%. It is ...
Alpod-CV from Altar LS, Cefpodoxime - Cafage-Cl-P to Cefage O | Cefpodoxime (marketed as the prodrug cefpodoxime proxetil by Pharmacia & Upjohn under the trade name Vantin and under the name Orelox by Sanofi-Aventis), is an oral third generation cephalosporin. Use of Alpod-CV from Altar LS, Pregnancy, lactation in childrens and special precautions for Alpod-CV from Altar LS, prices of Alpod-CV from Altar LS . It is active against most Gram positive and Gram negative organisms. Notable exceptions include Pseudomonas aeruginosa, Enterococcus, and Bacteroides fragilis. It is commonly used to treat acute otitis media, pharyngitis, and sinusitis. It also finds use as oral continuation therapy when intravenous cephalosporins (such as ceftriaxone) are no longer necessary for continued treatment., drugsupdate.com - Indias leading online platform for Doctors and health care professionals. Updates on Drugs, news, journals, 1000s of videos, national and international events, product-launches and much more..
Apodox from Uniroyal Biotech, Cefpodoxime - Cefonetic to Ceftop SYR | Cefpodoxime (marketed as the prodrug cefpodoxime proxetil by Pharmacia & Upjohn under the trade name Vantin and under the name Orelox by Sanofi-Aventis), is an oral third generation cephalosporin. Use of Apodox from Uniroyal Biotech, Pregnancy, lactation in childrens and special precautions for Apodox from Uniroyal Biotech, prices of Apodox from Uniroyal Biotech . It is active against most Gram positive and Gram negative organisms. Notable exceptions include Pseudomonas aeruginosa, Enterococcus, and Bacteroides fragilis. It is commonly used to treat acute otitis media, pharyngitis, and sinusitis. It also finds use as oral continuation therapy when intravenous cephalosporins (such as ceftriaxone) are no longer necessary for continued treatment., drugsupdate.com - Indias leading online platform for Doctors and health care professionals. Updates on Drugs, news, journals, 1000s of videos, national and international events, product
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Acute otitis media caused by H. influenzae, S. pneumoniae, and Moraxella catarrhalis Children ages 5 months to 12 years: 5 mg/kg P.O. q 12 hours (maximum of 200 mg/dose) or 10 mg/kg q 24 hours (maximum of 400mg/dose) for 10 days ...
Cefpodoxime proxetil is an orally administered, extended spectrum, semi-synthetic antibiotic of the cephalosporin class. The chemical name is (RS)-1(isopropoxycarbonyloxy) ethyl (+)-(6R,7R)-7-[2-(2-amino-4-thiazolyl)-2-{(Z)methoxyimino}acetamido]-3-methoxymethyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate. Its empirical formula is CHNOS and its structural formula is represented below: The molecular weight of cefpodoxime proxetil is… Continue Reading → ...
Antibiotic tablets for the treatment of skin infections (wounds and abscesses in dogs caused by susceptible strains of bacteria).
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Cefpodoxime is an extended spectrum semi-synthetic antibiotic which belongs to the third generation of cephalosporins. It inhibits bacterial cell wall synthesis leading to bacterial cell death. Cefpodoxime is given as Cefpodoxime proxetil (prodrug) which is hydrolyzed in the intestinal epithelium to release active drug Cefpodoxime. It is active against broad spectrum of Gram +ve & Gram -ve bacteria. Organisms resistant to penicillins and some cephalosporins due to their b-lactamases secretion are susceptible to Cefpodoxime. It is effective for longer duration with higher clinical success rate and low incidence of side effects ...
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DEVELOPMENT OF VALIDATED HPTLC METHOD FOR SIMULTANEOUS DETERMINATION OF LEVOFLOXACIN HEMIHYDRATE AND CEFPODOXIME PROXETIL IN SYNTHETIC MIXTURE AND TABLET DOSAGE FORM ...
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일정한 이온 세기의 알칼리 용액에서 과망간산에 의한 프포독심 프록세틸(Cefpodoxime Proxetil)의 산화의 속도론적 경로가 분광광도법적으로 연구되었다. 그 반응은 과망간산 이온 농도에서 일차 속도론적으로 나타났으며, 프포독심 산과 알칼리 농도에서 단일 이하의 차수를 나타내었다. 용매의 이온 세기가 증가함에 따라 속도도 증가하였다. 산화 반응은 프포독심 산과 함께 복합체를 형성하는 알칼리-과망간산 종들을 통하여 진행된다. 반응물을 만들기 위해서 프포독심 산의 자유 라디칼과 과망간산의 다른 분자 사이의 빠른 반응에 이어서 다음 분해가 천천히 진행된다. 다양한 온도에서 반응의 조사는 제안하는 메커니즘의 느린 단계를 고려한 활성화 변수들의 결정할 수 있게 하고 일차 속도론을 따른다. 제안하는 메커니즘과 유도된 속도 법칙들은 관찰된 ...
Abstract Cefditoren pivoxil (Spectracef®, Meiact®) is a third-generation oral cephalosporin with a broad spectrum of activity against pathogens, including both Gram-positive and -negative bacteria,...
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... is a third-generation cephalosporin available for parenteral administration. Unlike other third-generation ... Aldridge KE (1990). "An update on the in vitro activity of ceftizoxime and other cephalosporin/cephamycin antimicrobial agents ... cephalosporins, the whole C-3 side chain in ceftizoxime has been removed to prevent deactivation by hydrolytic enzymes. It ...
"Eggerthella lenta bacteremia successfully treated with ceftizoxime: case report and review of the literature". European Journal ...
Presently, all tested strains of P. penneri have been found to be highly susceptible to: ceftizoxime ceftazidime moxalactam ... In vitro studies of ceftizoxime, ceftazidime, moxalactam, and cefoxitin suggest these agents also may prove to be clinically ...
... for example ceftizoxime, cefotaxime, ceftriaxone, and ceftazidime, as well as the oxyimino-monobactam aztreonam), but not 7- ...
... ceftizoxime alapivoxil (INN) ceftizoxime (INN) ceftobiprole (INN) ceftolozane (USAN, INN) Ceftriaxone ceftriaxone (INN) ...
... ceftizoxime MeSH D02.065.589.099.249.190.190.155 - ceftriaxone MeSH D02.065.589.099.249.190.190.165 - cefuroxime MeSH D02.065. ...
Cefotaxime J01DD02 Ceftazidime J01DD03 Cefsulodin J01DD04 Ceftriaxone J01DD05 Cefmenoxime J01DD06 Latamoxef J01DD07 Ceftizoxime ...
... ceftizoxime 1983 - norfloxacin 1984 - cefonicid 1984 - cefotetan 1984 - temocillin 1985 - cefpiramide 1985 - imipenem/ ...
HomeMicrobiologyAntimicrobial Susceptibility Testing Strips, Disks and Cartridges Zox30 Ceftizoxime. Previous product. ...
List of Ceftizoxime Sodium API Standards
Ceftizoxime is used for the treatment of bone and joint infections, intra-abdominal infections, meningitis, lower respiratory ... Ceftizoxime is commercially available as the sodium salt.. Potency of ceftizoxime sodium is expressed in terms of ceftizoxime. ... Ceftizoxime Sodium Parenteral For injection 500 mg (of ceftizoxime) Cefizox®, Fujisawa 1 g (of ceftizoxime) Cefizox®, Fujisawa ... The sodium salt of ceftizoxime contains 2.6 mEq of sodium per gram of ceftizoxime. Reconstituted solutions of ceftizoxime ...
Ceftizoxime. -. -. ,=38. -. ,=0.5. Ceftriaxone. -. -. ,=35. -. ,=0.25. Cefmetazole. ,=27. 28-32. ,=33. ,=8. ,=2. ...
Ceftizoxime. ≤1. ≥64. ≥64. Cefepime. 2. ≥64. ≥64. Cefotetan. ≤4. ≥64. ≥64. ...
Ceftizoxime 500 mg IM. or. Cefotaxime 500 mg IM. or. Cefotetan 1 g IM ...
The bone-targeted long-circulating liposomal 99mtechnetium-ceftizoxime showed higher uptake in regions of septic inflammation ... In this work, long-circulating and alendronate-coated liposomes containing 99mtechnetium-radiolabeled ceftizoxime were prepared ... These results show that long-circulating and alendronate-coated liposomes containing 99mtechnetium-radiolabeled ceftizoxime ... Alendronate-coated long-circulating liposomes containing 99mtechnetium-ceftizoxime used to identify osteomyelitis Diego dos ...
Ceftizoxime: (Moderate) It would be prudent to recommend alternative or additional contraception when oral contraceptives (OCs ...
Ceftizoxime D2.886.675.966.500.249.190.190.145 D2.886.665.74.190.190.145. D4.75.80.875.99.221.249.190.190.145. Ceftriaxone ...
Ceftizoxime. When taken with amoxicillin, bromelain was shown to increase absorption of amoxicillin in humans. When 80 mg of ...
Alternative Initial Regimens Cefotaxime 1 g IV every 8 hours or Ceftizoxime 1 g IV every 8 hours or For persons allergic to B- ... Of these four regimens, ceftizoxime 500 mg appears to be the most effective according to cumulative experience in published ... ceftizoxime 500 mg IM in a single dose; cefotaxime 500 mg IM in a single dose; cefotetan 1 g IM in a single dose; and cefoxitin ...
Ceftizoxime (2 gm every 12 hours) and cefoxitin (2 gm every six hours) were compared. There were no significant differences ... Ninety-seven percent of patients treated with ceftizoxime and 89% of those treated with cefoxitin were cured or improved; there ... with ceftizoxime, can be accomplished by a twice-daily dosing regimen. ...
Ceftizoxime sodium 10 mg/ml 103. Promethazine hydrochloride 2 mg/ml Ceftobiprole medocaril sodium 2 mg/ml 2269. ...
Ceftizoxime-induced immune hemolytic anemia associated with multi-organ failure. Announcements. Yeungnam Univ J Med. Date of ...
Ceftizoxime. Clindamycin(Low Risk). Lomefloxacin(Low Risk). Carbenicillin Indanyl Disodium(Safe). Nitrofurantoin(Safe) ...
Equivalent to Ceftizoxime 3000 mg. Packs Available vial size : 2.5 & 3 gm ...
SUCCESSFUL ERADICATION OF FLAVOBACTERIUM MENINGOSEPTICUM NEONATAL MENINGITIS WITH CEFTIZOXIME. Zulfiqar A. Bhutta , et al ...
CEFTIZOXIME 57033 CLAVULANATE 57034 PHOSPHORUS 57036 CLOFAZIMINE 57038 PIRBUTEROL 57040 MECLOCYCLINE 57042 ACLOMETASONE 57044 ...
... ceftizoxime, clarithromycin, diltiazem, esmolol, fluconazole, insulin, labetalol, lorazepam, linezolid, magnesium sulfate, ...
Ceftizoxime. Ceftizoxime. RxNorm. Medication Treatment (STD). Details. 2193. Ceftriaxone. Ceftriaxone. RxNorm. Medication ...
Ceftizoxime. ≤1. ≥64. ≥64. Cefepime. 2. ≥64. ≥64. Cefotetan. ≤4. ≥64. ≥64. ...
Ceftizoxime Sodium Entry term(s). Ceftizoxime Monosodium Salt Monosodium Salt, Ceftizoxime Salt, Ceftizoxime Monosodium Sodium ... Ceftizoxime Entry term(s):. Cefizox. Ceftizoxime Monosodium Salt. Ceftizoxime Sodium. FK 749. FK-749. FK749. FR 13749. FR-13749 ... Salt, Ceftizoxime Monosodium. Sodium, Ceftizoxime. Tree number(s):. D02.065.589.099.249.190.190.145. D02.886.665.074.190.190. ... Ceftizoxime - Preferred Concept UI. M0023550. Scope note. A semisynthetic cephalosporin antibiotic which can be administered ...
Empirical administration ceftizoxime 2g q12h intravenously. The joint cavity was punctured again on the 10th postoperative day ...
InChI=1S/C25H27N9O8S2/c1-3-32-8-9-33(21(39)20(32)38)24(42)27-15(12-4-6-14(35)7-5-12)18(36)26-16-19(37)34-17(23(40)41)13(10-43-22(16)34)11-44-25-28-29-30-31(25)2/h4-7,15-16,22,35H,3,8-11H2,1-2H3,(H,26,36)(H,27,42)(H,40,41)/t15-,16-,22-/m1/s1 ...
  • The antibiotic with high degree of photosensitivity is a. tetracycline b. gentamicin c. ampicillin d. ceftizoxime 2. (ruhulalam.com)
  • Treatment and long-term follow-up of foot infections in patients with diabetes or ischemia: a randomized, prospective, double-blind comparison of cefoxitin and ceftizoxime. (uchicago.edu)
  • Comparison of azlocillin, ceftizoxime, cefoxitin, and amikacin alone and in combination against Pseudomonas aeruginosa in a neutropenic-site rabbit model. (uchicago.edu)
  • Manually determine the antibiotic susceptibility of microorganisms using Antimicrobial Susceptibility Testing (AST) methods in conjunction with reliable, easy-to-use Thermo Scientific™ Oxoid™ Ceftizoxime Antimicrobial Susceptibility Disks. (labmal.com)
  • Ceftizoxime is a semisynthetic, third generation cephalosporin antibiotic. (antiinfectivemeds.com)
  • and septicemia caused by susceptible S. pneumoniae, other streptococci (except enterococci), or S. aureus.Ceftizoxime generally should not be used in the treatment of infections caused by gram-positive bacteria when a penicillin or a first generation cephalosporin could be used. (antiinfectivemeds.com)
  • The drug also is used for the treatment of gonorrhea and pelvic inflammatory disease.In addition, ceftizoxime has been used for perioperative prophylaxis. (antiinfectivemeds.com)
  • Ceftizoxime therapy may be started pending results of susceptibility tests but should be discontinued if the causative organism is found to be resistant to the drug. (antiinfectivemeds.com)
  • The manufacturer states that, because high concentrations of ceftizoxime are attained in urine, the drug may be used alone in the treatment of urinary tract infections caused by susceptible Ps. (antiinfectivemeds.com)
  • Ceftizoxime is used for the treatment of bone and joint infections, intra-abdominal infections, meningitis, lower respiratory tract infections, septicemia, skin and skin structure infections, and urinary tract infections caused by susceptible bacteria. (antiinfectivemeds.com)
  • aeruginosa are only susceptible to high concentrations of ceftizoxime in vitro, many clinicians state that ceftizoxime should not be used alone in the treatment of any infection where Ps. (antiinfectivemeds.com)
  • Ceftizoxime is used in the treatment of lower respiratory tract, intra-abdominal, or skin and skin structure infections caused by susceptible Bacteroides (including B. fragilis) and in the treatment of skin and skin structure infections caused by susceptible anaerobic cocci (including Peptococcus and Peptostreptococcus). (antiinfectivemeds.com)
  • ceftizoxime 31 anti diarroheal combination bolus ( quiniodochlor + furazolidone + atropine ) 32 other anti diarroheal combinations 33 lnj. (punjabtenders.net)
  • Cefizox ® (ceftizoxime injection) in the Galaxy ® plastic container (PL 2040) contains ceftizoxime as ceftizoxime sodium. (nih.gov)
  • Cefizox (ceftizoxime injection) in the Galaxy ® plastic container is a frozen iso-osmotic, sterile, nonpyrogenic premixed 50 mL solution containing 1 g or 2 g of ceftizoxime as ceftizoxime sodium. (nih.gov)
  • Role of serum protein binding and multiple antibiotic doses in the extravascular distribution of ceftizoxime and cefotaxime. (uchicago.edu)
  • Methodology: Nasal and skin behind the ear swabs from pigs and nasal swabs from humans were enriched in Mueller Hinton broth with 6.5% sodium chloride, followed by phenol red mannitol broth with 75 mg/L aztreonam and 5 mg/L ceftizoxime. (jidc.org)
  • NOTE: Methicillin-resistant staphylococci are resistant to cephalosporins, including ceftizoxime. (nih.gov)
  • 1. Antibacterial activity of MEPM The minimum inhibitory concentrations (MICs) of MEPM against a total of 321 clinically isolated strains were measured and compared with those of imipenem/cilastatin (IPM/CS), ceftazidime, cefuzonam and ceftizoxime, using the MIC-2000 system (Dynatech Laboratories). (elsevier.com)
  • Comparative tissue and extravascular fluid concentrations of ceftizoxime. (nih.gov)
  • Pharmacokinetics, protein binding, and extravascular distribution of ceftizoxime in normal subjects. (uchicago.edu)
  • 2020. https://www.drugguide.com/ddo/view/Davis-Drug-Guide/109028/all/ceftizoxime. (drugguide.com)
  • Five women were given 1 gram of ceftizoxime intravenously. (nih.gov)
  • In six women given 1 gram of ceftizoxime intravenously, average milk levels were 0.25 mg/L 1 hour after the dose. (nih.gov)
  • Ceftizoxime is highly resistant to a broad spectrum of beta-lactamases (penicillinase and cephalosporinase), including Richmond types I, II, III, TEM, and IV, produced by both aerobic and anaerobic gram-positive and gram-negative organisms. (nih.gov)
  • Management: Antibiotics (ceftizoxime, metronidazole and amoxicillin/clavulanate potassium), parenteral nutrition and ileocecectomy. (elsevier.com)
  • Ceftizoxime is a third-generation cephalosporin with broad-spectrum gram-negative activity. (medscape.com)
  • Hainan Haiyao Co. Ltd offers a wide range of products which includes Injection ceftizoxime. (cphi-online.com)
  • Since 2003, 860 human infections include ceftizoxime (500 mg, administered IM). (foxholeconsulting.com)
  • Doxycycline en ligne.Pristinamycine (peaux et tissus mous) Clindamycine (300 buy generic viagra online mg x 4/j) Fluoroquinolones (tous sites) Cotrimoxazole (infections urinaires, respiratoires, cutanées) Doxycycline (infections cutanées, urinaires, respiratoires) Linézolide (infections cutanées, respiratoires, osseuses).According to cialis 5 mg efectos secundarios medical sources, the frequency of depression levitra 40 among doxycycline users is unknown due to lack of reporting.Doxycycline For Ureaplasma Urealyticum. (ultrasensesolutions.com)
  • After a single 1 gram intravenous dose of ceftizoxime in 2 women, milk levels ranged from 0.31 to 0.43 mg/L from 2 to 8 hours after the dose. (nih.gov)
  • Limited information indicates that ceftizoxime produces low levels in milk that are not expected to cause adverse effects in breastfed infants. (nih.gov)
  • The bactericidal action of ceftizoxime results from inhibition of cell-wall synthesis. (nih.gov)
  • Les données sur l'acte chirurgical, le choix des antibiotiques et leur administration ont été collectées pour toutes les interventions chirurgicales réalisées chez des patients hospitalisés pendant 15 jours en mars 2010. (who.int)
  • Diuretics should give an action that is soluble 1:1.2 in water (1:4), in alcohol hut practically insoluble in ether (1:49) or benzene (i: Of an aqueous ceftizoxime is not there yet. (equalitymi.org)
  • Medications frequently used for diagnostic purposes refers to conventional chemotherapy before administration hours hours tiotropium inhalation mcg one inhalation every hours or ceftizoxime g iv every hours. (umaine.edu)