Cefsulodin
Cefotiam
Cephalosporins
Mezlocillin
Peptidoglycan Glycosyltransferase
Pseudomonas aeruginosa
beta-Lactams
Four-membered cyclic AMIDES, best known for the PENICILLINS based on a bicyclo-thiazolidine, as well as the CEPHALOSPORINS based on a bicyclo-thiazine, and including monocyclic MONOBACTAMS. The BETA-LACTAMASES hydrolyze the beta lactam ring, accounting for BETA-LACTAM RESISTANCE of infective bacteria.
beta-Lactamases
Microbial Sensitivity Tests
Carbenicillin
Marketing
Research Report
Dietetics
Journalism, Medical
Publications
Shiga-Toxigenic Escherichia coli
Shiga Toxin
Shiga Toxins
A class of toxins that inhibit protein synthesis by blocking the interaction of ribosomal RNA; (RNA, RIBOSOMAL) with PEPTIDE ELONGATION FACTORS. They include SHIGA TOXIN which is produced by SHIGELLA DYSENTERIAE and a variety of shiga-like toxins that are produced by pathologic strains of ESCHERICHIA COLI such as ESCHERICHIA COLI O157.
Escherichia coli O157
A verocytotoxin-producing serogroup belonging to the O subfamily of Escherichia coli which has been shown to cause severe food-borne disease. A strain from this serogroup, serotype H7, which produces SHIGA TOXINS, has been linked to human disease outbreaks resulting from contamination of foods by E. coli O157 from bovine origin.
Shiga Toxin 2
Hemolysin Proteins
Chromogenic Compounds
Colorless, endogenous or exogenous pigment precursors that may be transformed by biological mechanisms into colored compounds; used in biochemical assays and in diagnosis as indicators, especially in the form of enzyme substrates. Synonym: chromogens (not to be confused with pigment-synthesizing bacteria also called chromogens).
Culture Media
Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.
Agar
A complex sulfated polymer of galactose units, extracted from Gelidium cartilagineum, Gracilaria confervoides, and related red algae. It is used as a gel in the preparation of solid culture media for microorganisms, as a bulk laxative, in making emulsions, and as a supporting medium for immunodiffusion and immunoelectrophoresis.
Cronobacter sakazakii
Candida
A genus of yeast-like mitosporic Saccharomycetales fungi characterized by producing yeast cells, mycelia, pseudomycelia, and blastophores. It is commonly part of the normal flora of the skin, mouth, intestinal tract, and vagina, but can cause a variety of infections, including CANDIDIASIS; ONYCHOMYCOSIS; vulvovaginal candidiasis (CANDIDIASIS, VULVOVAGINAL), and thrush (see CANDIDIASIS, ORAL). (From Dorland, 28th ed)
Encyclopedias as Topic
MedlinePlus
Thermococcus
Consumer Health Information
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Pyrococcus
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Sick Sinus Syndrome
A condition caused by dysfunctions related to the SINOATRIAL NODE including impulse generation (CARDIAC SINUS ARREST) and impulse conduction (SINOATRIAL EXIT BLOCK). It is characterized by persistent BRADYCARDIA, chronic ATRIAL FIBRILLATION, and failure to resume sinus rhythm following CARDIOVERSION. This syndrome can be congenital or acquired, particularly after surgical correction for heart defects.
Pacemaker, Artificial
Dichlorodiphenyldichloroethane
Heart Block
Impaired conduction of cardiac impulse that can occur anywhere along the conduction pathway, such as between the SINOATRIAL NODE and the right atrium (SA block) or between atria and ventricles (AV block). Heart blocks can be classified by the duration, frequency, or completeness of conduction block. Reversibility depends on the degree of structural or functional defects.
Cardiac Pacing, Artificial
Genetic Code
Fast lysis of Escherichia coli filament cells requires differentiation of potential division sites. (1/46)
Periodic activation of zonal peptidoglycan (murein) synthesis at division sites in Escherichia coli has been reported recently. Zonal synthesis is responsible for septum formation, whereas elongation of the cell sacculus is performed by diffuse insertion of precursors. Zonal synthesis can be triggered in ftsA, ftsQ and ftsI (pbpB) division mutants growing as filaments at the restrictive temperature, but not in ftsZ mutant strains. The lytic response to beta-lactams of cells able or unable to periodically trigger a zonal mode of murein synthesis could be substantially different. Therefore, we investigated the response to the bacteriolytic beta-lactam cefsulodin of ftsZ and ftsI mutants growing at the restrictive (42 degrees C) temperature. The ftsI cells lysed early and quickly after addition of the antibiotic. Sacculi of lysed cells were transversely cut in a very sharp way. In contrast the ftsZ strain lysed late and slowly after addition of the antibiotic and sacculi showed a generalized weakening of the murein network and extended breaks with a frayed appearance. No transversely cut sacculi comparable to those seen in the ftsI samples were found. Our results strongly support that beta-lactam-induced lysis occurs preferentially at division sites because of the activation of zonal murein synthesis at the initiation of septation. (+info)Comparative in vitro activities of SCE-129, sulbenicillin, gentamicin, and dibekacin against Pseudomonas. (2/46)
Against sulbenicillin- and gentamicin-susceptible strains of Pseudomonas aeruginosa, SCE-129 was about 10 times more active than sulbenicillin and had a similar activity to gentamicin and dibekacin. Sulbenicillin-resistant strains of P. aeruginosa were moderately resistant to SCE-129, whether these strains were gentamicin-resistant or not. Gentamicin-resistant strains of P. aeruginosa were resistant to dibekacin but not to SCE-129. Against P. maltophilia, the minimum inhibitory concentration of SCE-129 resembled those of sulbenicillin, gentamicin, and dibekacin. Most strains of P. cepacia were moderately resistant to SCE-129 and sulbenicillin and highly resistant to gentamicin and dibekacin. (+info)Cross-resistance to meropenem, cephems, and quinolones in Pseudomonas aeruginosa. (3/46)
Multiple-drug-resistant mutants were isolated from Pseudomonas aeruginosa PAO1 on agar plates containing ofloxacin and cefsulodin. These mutants were four to eight times more resistant to meropenem, cephems, carbenicillin, quinolones, tetracycline, and chloramphenicol than the parent strain was. In contrast, these mutants showed no significant changes in their susceptibilities to all carbapenems except meropenem. In these mutants, the amounts of an outer membrane protein with an apparent molecular weight of 49,000 (designated OprM) were increased compared with the amount in PAO1. Multiple-drug-resistant mutants of this type were also isolated from PAO1 on agar plates containing meropenem. Approximately 5% of clinical isolates showed cross-resistance to meropenem, cephems, and quinolones, concomitant with overproduction of OprM. Moreover, these two phenotypes, i.e., multiple-drug resistance and overproduction of OprM, were cotransferable by transduction. These data suggest that overproduction of OprM is associated with cross-resistance to meropenem, cephems, and quinolones in P. aeruginosa. The ofloxacin-cefsulodin-resistant mutant required higher concentrations of meropenem to induce beta-lactamase than PAO1 did, indicating the possibility that this mutation involves decreased outer membrane permeability to meropenem. (+info)Unstable Escherichia coli L forms revisited: growth requires peptidoglycan synthesis. (4/46)
Growing bacterial L forms are reputed to lack peptidoglycan, although cell division is normally inseparable from septal peptidoglycan synthesis. To explore which cell division functions L forms use, we established a protocol for quantitatively converting a culture of a wild-type Escherichia coli K-12 strain overnight to a growing L-form-like state by use of the beta-lactam cefsulodin, a specific inhibitor of penicillin-binding proteins (PBPs) 1A and 1B. In rich hypertonic medium containing cefsulodin, all cells are spherical and osmosensitive, like classical L forms. Surprisingly, however, mutant studies showed that colony formation requires d-glutamate, diaminopimelate, and MurA activity, all of which are specific to peptidoglycan synthesis. High-performance liquid chromatography analysis confirmed that these L-form-like cells contain peptidoglycan, with 7% of the normal amount. Moreover, the beta-lactam piperacillin, a specific inhibitor of the cell division protein PBP 3, rapidly blocks the cell division of these L-form-like cells. Similarly, penicillin-induced L-form-like cells, which grow only within the agar layers of rich hypertonic plates, also require d-glutamate, diaminopimelate, and MurA activity. These results strongly suggest that cefsulodin- and penicillin-induced L-form-like cells of E. coli-and possibly all L forms-have residual peptidoglycan synthesis which is essential for their growth, probably being required for cell division. (+info)The Rcs phosphorelay is a cell envelope stress response activated by peptidoglycan stress and contributes to intrinsic antibiotic resistance. (5/46)
(+info)Cell cycle-independent lysis of Escherichia coli by cefsulodin, an inhibitor of penicillin-binding proteins 1a and 1b. (6/46)
Cefsulodin lyses actively growing Escherichia coli by binding specifically to penicillin-binding proteins (PBPs) 1a and 1b. Recent findings (F. Garcia del Portillo, M. A. de Pedro, D. Joseleau-Petit, and R. D'Ari, J. Bacteriol. 171:4217-4221, 1989) have linked cefsulodin-induced lysis to septation during the first division cycle after a nutritional shift-up or chromosome replication realignment. We synchronized cells by membrane filtration to determine whether cefsulodin-induced lysis depended on septation in normally growing cells. Populations of newly divided cells were allowed to grow for variable lengths of time. Cefsulodin was added to these synchronous cultures, which represented points in two to three rounds of the cell cycle. Since the cell numbers were small, a new lysis assay was developed that was based on the release of DNA measured by fluorometry. Lysis occurred at a constant time after addition of the antibiotic, regardless of the time in the cell cycle at which the addition was made. Thus, cefsulodin-induced lysis is not linked to septation or to any other cell cycle-related event. (+info)Lysis of Escherichia coli by beta-lactams which bind penicillin-binding proteins 1a and 1b: inhibition by heat shock proteins. (7/46)
The heat shock proteins (HSPs) of Escherichia coli were artificially induced in cells containing the wild-type rpoH+ gene under control of a tac promoter. At 30 degrees C, expression of HSPs produced cells that were resistant to lysis by cephaloridine and cefsulodin, antibiotics that bind penicillin-binding proteins (PBPs) 1a and 1b. This resistance could be reversed by the simultaneous addition of mecillinam, a beta-lactam that binds PBP 2. However, even in the presence of mecillinam, cells induced to produce HSPs were resistant to lysis by ampicillin, which binds all the major PBPs. Lysis of cells induced to produce HSPs could also be effected by imipenem, a beta-lactam known to lyse nongrowing cells. These effects suggest the existence of at least two pathways for beta-lactam-dependent lysis, one inhibited by HSPs and one not. HSP-mediated lysis resistance was abolished by a mutation in any one of five heat shock genes (dnaK, dnaJ, grpE, GroES, or groEL). Thus, resistance appeared to depend on the expression of the complete heat shock response rather than on any single HSP. Resistance to lysis was significant in the absence of the RelA protein, implying that resistance could not be explained by activation of the stringent response. Since many environmental stresses promote the expression of HSPs, it is possible that their presence contributes an additional mechanism toward development in bacteria of phenotypic tolerance to beta-lactam antibiotics. (+info)Isolation of Neisseria meningitidis mutants deficient in class 1 (porA) and class 3 (porB) outer membrane proteins. (8/46)
The class 1 major outer membrane protein of Neisseria meningitidis is a serious candidate for a meningococcal vaccine. To facilitate studies on the function of this protein, mutants were isolated that lacked this protein or the structurally related class 3 protein. These mutants were obtained by using the antibody-dependent bactericidal action of the complement system. The class 1 protein-deficient strain grew normally in vitro, whereas growth of the class 3 protein-deficient strain was slightly retarded. The class 3 protein-deficient strain displayed increased resistance to the antibiotics tetracycline and cefsulodin, which is consistent with the proposed role of the protein as a pore-forming protein. The class 1 protein was purified to homogeneity from the class 3 protein-deficient strain. Lipid bilayer experiments revealed that this protein also formed pores. The class 1 protein pores were cation selective. (+info)
Cefsulodin Sodium (CAS 52152-93-9) Market Research Report 2018
Cefsulodin
Summary Report | CureHunter
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Снобус.ру. Блог с картинками. Мода, знаменитости, фотография.
ATSCP2 - PCR Primer Pair - SYBR | PrimePCR | Bio-Rad
Gematria value of phosphorus is 696 - English, Hebrew and Simple Gematria Calculator Values
Cefmenoxime - Drugs.com
Study of clinical bacteriological efficacy in a cefmenoxime o...
ATC kod J01
J01DD03 Cefsulodin. J01DD04 Ceftriakson. J01DD05 Cefmenoksim. J01DD06 Latamoksef. J01DD07 Ceftizoksim. J01DD08 Cefiksim. ...
TAP Pharmaceuticals
The first products TAP file new drug applications for, were two cephalosporins, cefmenoxime (Cefmax) and cefsulodin (Cefonomil ...
List of drugs: Cb-Ce
... cefsulodin (INN) cefsumide (INN) ceftazidime (INN) ceftaroline fosamil (INN) cefteram (INN) ceftezole (INN) ceftibuten (INN) ...
ATC code J01
Ceforanide J01DC12 Cefminox J01DC13 Cefbuperazone J01DC14 Flomoxef J01DD01 Cefotaxime J01DD02 Ceftazidime J01DD03 Cefsulodin ...
Timeline of antibiotics
... cefsulodin 1981 - latamoxef 1981 - netilmicin 1982 - ceftriaxone 1982 - micronomicin 1983 - cefmenoxime 1983 - ceftazidime 1983 ...
Cefsulodin
... is most commonly used in cefsulodin-irgasan-novobiocin agar to select for Yersinia microorganisms. This agar is most ... Cefsulodin is a third-generation cephalosporin antibiotic that is active against Pseudomonas aeruginosa and was discovered by ... TAP Pharmaceuticals had a new drug application on file with FDA for cefsulodin under the brand name Cefonomil as of 1985. ... "BAM Media M35: Cefsulodin-Irgasan Novobiocin Agar or Yersinia Selective Agar". Retrieved 2 September 2012. http://antibiotics. ...
Cefuroxime axetil
InChI=1S/C20H22N4O10S/c1-9(25)33-10(2)34-19(28)15-11(7-32-20(21)29)8-35-18-14(17(27)24(15)18)22-16(26)13(23-30-3)12-5-4-6-31-12/h4-6,10,14,18H,7-8H2,1-3H3,(H2,21,29)(H,22,26)/b23-13-/t10?,14-,18-/m1/ ...
Benzylpenicillin
The production of benzylpenicillin involves fermentation, recovery and purification of the penicillin.[10] The fermentation process of the production of benzylpencillin is about obtaining the product. The presence of the product in solution inhibits the reaction and reduces the product rate and yield. Thus, in order to obtain the most product and increase the rate of reaction the product, would be continuously extracted out.[11] This is done by having the mold with either glucose, sucrose, lactose, startch, or detrin, nitrate, ammonium salt, corn steep liquor, peptone, meat or yeast extract, and little amounts of inorganic salts.[12] The recovery of the benzylpencillin is the most important part of the production process because it affects the purification steps if done wrong.[10] There are many different types of techniques to recover benzyl penicillin, aqueous two-phase extraction, liquid membrane extraction, microfiltration technique, and solvent subulation[10] Extraction is more commonly ...
Meropenem
... , sold under the brandname Merrem among others, is a broad-spectrum antibiotic used to treat a variety of bacterial infections.[1] Some of these include meningitis, intra-abdominal infection, pneumonia, sepsis, and anthrax.[1] It is given by injection into a vein.[1] Common side effects include nausea, diarrhea, constipation, headache, rash, and pain at the site of injection.[1] Serious side effects include Clostridium difficile infection, seizures, and allergic reactions including anaphylaxis.[1] Those who are allergic to other β-lactam antibiotics are more likely to be allergic to meropenem.[1] Use in pregnancy appears to be safe.[1] It is in the carbapenem family of medications.[1] Meropenem usually results in bacterial death through blocking their ability to make a cell wall.[1] It is more resistant to breakdown β-lactamase producing bacteria.[1] Meropenem was patented in 1983.[2] It was approved for medical use in the United States in 1996.[1] It is on the World Health ...
Cefetamet
InChI=1S/C14H15N5O5S2/c1-5-3-25-12-8(11(21)19(12)9(5)13(22)23)17-10(20)7(18-24-2)6-4-26-14(15)16-6/h4,8,12H,3H2,1-2H3,(H2,15,16)(H,17,20)(H,22,23)/b18-7-/t8-,12-/m1/ ...
Nafcillin
Bonow RO, Carabello BA, Kanu C, et al. (August 2006). "ACC/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (writing committee to revise the 1998 Guidelines for the Management of Patients With Valvular Heart Disease): developed in collaboration with the Society of Cardiovascular Anesthesiologists: endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons". Circulation. 114 (5): e84-231. doi:10.1161/CIRCULATIONAHA.106.176857. PMID 16880336 ...
Phenoxymethylpenicillin
Penicillin V is sometimes used in the treatment of odontogenic infections.. It is less active than benzylpenicillin (penicillin G) against Gram-negative bacteria.[9][10] Phenoxymethylpenicillin has a range of antimicrobial activity against Gram-positive bacteria that is similar to that of benzylpenicillin and a similar mode of action, but it is substantially less active than benzylpenicillin against Gram-negative bacteria.[9][10]. Phenoxymethylpenicillin is more acid-stable than benzylpenicillin, which allows it to be given orally.. Phenoxymethylpenicillin is usually used only for the treatment of mild to moderate infections, and not for severe or deep-seated infections since absorption can be unpredictable. Except for the treatment or prevention of infection with Streptococcus pyogenes (which is uniformly sensitive to penicillin), therapy should be guided by bacteriological studies (including sensitivity tests) and by clinical response.[11] People treated initially with parenteral ...
Ceftolozane
The in vitro activity of ceftolozane-tazobactam has been examined in five surveillance studies of isolates from Europe and North America.[8] In these studies, ceftolozane-tazobactam was notable for its activity against Pseudomonas aeruginosa, a moderately common cause of hospital-acquired infections that is commonly multi-drug resistant. Ninety percent of P. aeruginosa isolates were inhibited by a ceftolozane-tazobactam at a concentration of 4 μg/mL (MIC90), making it the most potent anti-pseudomonal antibiotic in clinical use. In these same studies, ceftolozane-tazobactam exhibited MIC90 values of ,1 μg/mL for Escherichia coli, Citrobacter koseri, Morganella morganii, Proteus mirabilis, Salmonella species, and Serratia marcescens. Somewhat poorer activity is observed for the Klebsiella and Enterobacter species, with the MIC90 for extended spectrum beta-lactamase (ESBL) expressing Klebsiella pneumonia being ,32 μg/mL. ...
Vancomycin
A set of multienzymes (peptide synthase CepA, CepB, and CepC) are responsible for assembling the heptapeptide. (Figure 2). The organization of CepA, CepB, and Cep C closely resembles other peptide synthases such as those for surfactin (SrfA1, SrfA2, and SrfA3) and gramicidin (GrsA and GrsB).[41] Each peptide synthase activates codes for various amino acids to activate each domain. CepA codes for modules 1, 2, and 3. CepB codes for modules 4, 5, and 6, and CepC codes for module 7. The three peptide synthases are located at the start of the region of the bacterial genome linked with antibiotic biosynthesis, and span 27 kb.[41]. After the linear heptapeptide molecule is synthesized, vancomycin has to undergo further modifications, such as oxidative cross-linking and glycosylation, in trans[clarification needed] by distinct enzymes, referred to as tailoring enzymes, to become biologically active (Figure 3). To convert the linear heptapeptide, eight enzymes, open reading frames (ORFs) 7, 8, 9, 10, ...
Cefminox
InChI=1S/C16H21N7O7S3/c1-22-15(19-20-21-22)33-4-7-3-32-14-16(30-2,13(29)23(14)10(7)12(27)28)18-9(24)6-31-5-8(17)11(25)26/h8,14H,3-6,17H2,1-2H3,(H,18,24)(H,25,26)(H,27,28)/t8-,14-,16+/m1/s1 ‹See TfM› ...
Cefdinir
... (SEF-di-nir) is a third-generation oral cephalosporin antibiotic sold under the brand names Cefzon and Omnicef. As of 2008, cefdinir, as Omnicef, was the highest-selling cephalosporin antibiotic in the United States, with more than US$585 million in retail sales of its generic versions alone.[1] Cefdinir is structurally similar to cefixime. It was discovered by Fujisawa Pharmaceutical Co., Ltd. (now Astellas) and introduced in 1991 under the brand name Cefzon.[2][3] Warner-Lambert licensed this cephalosporin for marketing in US from Fujisawa.[4] Abbott obtained U.S. marketing rights to Omnicef (cefdinir) in December 1998 through an agreement with Warner-Lambert Company.[5] It was approved by FDA on Dec 4, 1997.[6] It is available in US as Omnicef by Abbott Laboratories and in India as Cednir by Abbott, Kefnir by Glenmark, Cefdair by Xalra Pharma and Cefdiel by Ranbaxy. ...
Ceftolozane/tazobactam
Ceftolozane exerts bactericidal activities against susceptible gram-negative and gram-positive infections by inhibiting essential penicillin-binding proteins (PBPs), which are required for peptidoglycan cross-linking for bacterial cell wall synthesis, resulting in inhibition of cell wall synthesis and subsequent cell death. Ceftolozane is an inhibitor of PBPs of Pseudomonas aeruginosa (e.g. PBP1b, PBP1c, and PBP3) and E. coli (e.g., PBP3).[6][7] Tazobactam is a potent β-lactamase inhibitor of most common class A and C β-lactamases. Tazobactam has little clinically relevant in vitro activity against bacteria due to its reduced affinity to penicillin-binding proteins; however, it is an irreversible inhibitor of some β-lactamases (certain penicillinases and cephalosporinases) and can covalently bind to some chromosomal and plasmid-mediated bacterial beta-lactamases.[6] The addition of tazobactam strengthens the therapeutic response to ceftolozane, giving it the ability to treat a broader range ...
Cefprozil
... is a second-generation cephalosporin antibiotic. It can be used to treat ear infections, skin infections, and other bacterial infections.[citation needed] It comes as a tablet and as a liquid suspension. Although there is a widely quoted cross-allergy risk of 10% between cephalosporins and penicillin, an article[1] has shown no increased risk for cross-allergy for cefprozil and several other second-generation or later cephalosporins. It was patented in 1983 and approved for medical use in 1992.[2] ...
Imipenem/cilastatin
... has the ability to kill a wide variety of bacteria. Imipenem is the active antibiotic agent and works by interfering with their ability to form cell walls, so the bacteria break up and die. Imipenem is rapidly degraded by the renal enzyme dehydropeptidase if administered alone (making it less effective); the metabolites can cause kidney damage.[11] Imipenem is a broad-spectrum betalactam antibiotic used for severe bacterial infections caused by susceptible organisms. Because imipenem is rapidly inactivated by renal dehydropeptidase I, it is given in combination with cilastatin, a DHP-I inhibitor which increases half-life and tissue penetration of imipenem. Imipenem/cilastatin, like other carbapenems, binds to bacterial penicillin-binding proteins and interferes with bacterial cell wall integrity and synthesis. It has activity against many aerobic and anaerobic Gram-positive and Gram-negative organisms, including Staphylococcus aureus, Streptococcus pyogenes, S. agalactiae, S. ...
Stampa:Penicillin
Cefsulodin • Cefteram • Ceftibuten • Ceftiolene • Ceftizoxime • oxacephem (Flomoxef, Latamoxef ‡). ...
اسپکتینومایسین - ویکیپدیا
InChI=1S/C14H24N2O7/c1-5-4-6(17)14(20)13(21-5)22-12-10(19)7(15-2)9(18)8(16-3)11(12)23-14/h5,7-13,15-16,18-20H,4H2,1-3H3/t5-,7-,8+,9+,10+,11-,12-,13+,14+/m1/s1 ...
سفتریاکسون - ویکیپدیا
سفتریاکسون (آیوپاک آدی: (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-,2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)thio]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, اینگیلیسجه: Ceftriaxone, (چینجه:頭孢曲松)، عربجه: سيفترياكسون، روسجا: Цефтриаксон) بیر شیمیایی بیلشیک دواء. بۇ دواءنین مول جرمیسی مول/قرم ۵۵۴٫۵۸ دیر. نیمه عمر یا یاریلانما سۆرعتی ۵٫۸-۸٫۷ ساعات زامان آپاریر و آنتیبیوتیک اۆچون ایستیفاده اوْلونور. ...
سیکلوسرین - ویکیپدیا
سیکلوسرین (آیوپاک آدی: (R)-4-Amino-1,2-oxazolidin-3-one, اینگیلیسجه: Cycloserine, عربجه: سيكلوسيرين، روسجا: Циклосерин) بیر شیمیایی بیلشیک دواء. بۇ دواءنین مول جرمیسی مول/قرم ۱۰۲٫۰۹۲ دیر. متابولیسمی قاراجییرده باش وئریر. سیکلوسرین آنتیبیوتیک اۆچون ایستیفاده اوْلونور. ...
اسید نالیدیکسیک - ویکیپدیا
اسید نالیدیکسیک (آیوپاک آدی: 1-Ethyl-7-methyl-4-oxo-[1,8]naphthyridine-3-carboxylic acid, اینگیلیسجه: Nalidixic acid, عربجه: حمض الناليديكسيك، روسجا: Налидиксовая кислота) بیر شیمیایی بیلشیک دواء. بۇ دواءنین مول جرمیسی مول/قرم ۲۳۲٫۲۳۵ دیر. متابولیسمی قاراجییرده باش وئریر. اسید نالیدیکسیک آنتیبیوتیک اۆچون ایستیفاده اوْلونور. ...
বিটা ল্যাক্টাম - উইকিপিডিয়া
Cefsulodin • Cefteram • Ceftibuten • Ceftiolene • Ceftizoxime • oxacephem (Flomoxef, Latamoxef ‡) ...
سیلور سولفادیازین - ویکیپدیا
سیلور سولفادیازین (آیوپاک آدی: Silver [(4-aminophenyl)sulfonyl](pyrimidin-2-yl)azanide, اینگیلیسجه: Silver sulfadiazine, (چینجه:磺胺嘧啶银)) بیر شیمیایی بیلشیک دواء. بۇ دواءنین مول جرمیسی مول/قرم ۳۵۷٫۱۴ دیر. سیلور سولفادیازین آنتیبیوتیک اۆچون ایستیفاده اوْلونور. ...
استرپتومایسین - ویکیپدیا
InChI=1S/C21H39N7O12/c1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35/h4-18,26,29,31-36H,3H2,1-2H3,(H4,22,23,27)(H4,24,25,28)/t5-,6-,7+,8-,9-,10-,11+,12-,13-,14+,15+,16-,17-,18-,21+/m0/s1 ...
Cefsulodin - Wikipedia
Cefsulodin is most commonly used in cefsulodin-irgasan-novobiocin agar to select for Yersinia microorganisms. This agar is most ... Cefsulodin is a third-generation cephalosporin antibiotic that is active against Pseudomonas aeruginosa and was discovered by ... TAP Pharmaceuticals had a new drug application on file with FDA for cefsulodin under the brand name Cefonomil as of 1985. ... "BAM Media M35: Cefsulodin-Irgasan Novobiocin Agar or Yersinia Selective Agar". Retrieved 2 September 2012. http://antibiotics. ...
Cefsulodin | Harvard Catalyst Profiles | Harvard Catalyst
"Cefsulodin" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... This graph shows the total number of publications written about "Cefsulodin" by people in Harvard Catalyst Profiles by year, ... Below are the most recent publications written about "Cefsulodin" by people in Profiles. ... and whether "Cefsulodin" was a major or minor topic of these publication. ...
Cefsulodin
Summary Report | CureHunter
Cefsulodin: A pyridinium-substituted semisynthetic, broad-spectrum antibacterial used especially for Pseudomonas infections in ... Takeda Brand of Cefsulodin Sodium; CGP 7174 E; CGP7174E; Monosodium Salt, Cefsulodin; SCE 129; SCE129; Salt, Cefsulodin ... Cefsulodin. Subscribe to New Research on Cefsulodin A pyridinium-substituted semisynthetic, broad-spectrum antibacterial used ... 09/01/1984 - "Treatment of urinary tract infections due to Pseudomonas aeruginosa with cefsulodin.". 11/01/1986 - "Cefsulodin ...
Cefsulodin Sodium (CAS 52152-93-9) Market Research Report 2018
Market Research Report 2018 aims at providing comprehensive data on cefsulodin sodium market globally and regionally ... Cefsulodin sodium market forecast. 6. CEFSULODIN SODIUM MARKET PRICES. 6.1. Cefsulodin sodium prices in Europe. 6.2. Cefsulodin ... Cefsulodin sodium prices in North America. 6.4. Cefsulodin sodium prices in other regions. 7. CEFSULODIN SODIUM END-USE SECTOR ... 5. CEFSULODIN SODIUM MARKET WORLDWIDE 5.1. General cefsulodin sodium market situation, trends. 5.2. Manufacturers of cefsulodin ...
An abbreviated scheme for identification of Yersinia enterocolitica isolated from food enrichments on CIN (cefsulodin-irgasan...
Detection of Hemolysin Variants of Shiga Toxin-Producing Escherichia coli by PCR and Culture on VancomycinCefixime-Cefsulodin...
A vancomycin (8 mg/liter), cefixime (50 μg/liter), and cefsulodin (10 mg/liter) supplementation which differed from that in ... Detection of Hemolysin Variants of Shiga Toxin-Producing Escherichia coli by PCR and Culture on VancomycinCefixime-Cefsulodin ... Detection of Hemolysin Variants of Shiga Toxin-Producing Escherichia coli by PCR and Culture on VancomycinCefixime-Cefsulodin ... Detection of Hemolysin Variants of Shiga Toxin-Producing Escherichia coli by PCR and Culture on VancomycinCefixime-Cefsulodin ...
Cefsulodin sodium
Click to view prices and info for Cefsulodin Sodium on TOKU-E.com ... Buy and view Cefsulodin, part of Yersinia selective (CIN) agar ... Cefsulodin Stability Study. Cefsulodin 0.5mg/mL solution was observed to not degrade over a 4 day span at room temperature. ... Cefsulodin sodium is a third generation cephalosporin antibiotic.. Recently, TOKU-E has found that the main cause of cefsulodin ... For a complete list of cefsulodin MIC values, click here.. Media Supplements. Cefsulodin can be used as a selective agent in ...
MP Biomedicals | Fisher Scientific
Enrichment of persisters enabled by a ß-lactam-induced filamentation method reveals their stochastic single-cell awakening |...
... cefsulodin: p , 0.0001, n = 3 and n = 6; mecillinam: p , 0.0001, n = 5 and n = 9; ampicillin: p , 0.0001, n = 5 and n = 9; ... Cefsulodin is a ß-lactam that targets PBP1a and PBP1b, while mecillinam only targets PBP2. Ampicillin has multiple targets, ... Fraction of surviving cells after a 5-h treatment with cephalexin (50 µg/ml), aztreonam (0.64 µg/ml), cefsulodin (320 µg/ml), ... cefsulodin (320 µg/ml, 10x MIC), mecillinam (5 µg/ml, 40x MIC), ampicillin (40 µg/ml, 10x MIC), or ciprofloxacin (0.32 µg/ml, ...
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Cefoperazone1
- Piperacillin-cefoperazone-cefsulodin-fosfomycin-tobramycin synergism against Pseudomonas aeruginosa. (nii.ac.jp)
Third-generation cephalosporin2
- Cefsulodin is a third-generation cephalosporin antibiotic that is active against Pseudomonas aeruginosa and was discovered by Takeda Pharmaceutical Company in 1977. (wikipedia.org)
- Cefsulodin sodium is a third generation cephalosporin antibiotic. (toku-e.com)
Yersinia7
- Cefsulodin is most commonly used in cefsulodin-irgasan-novobiocin agar to select for Yersinia microorganisms. (wikipedia.org)
- An abbreviated scheme for identification of Yersinia enterocolitica isolated from food enrichments on CIN (cefsulodin-irgasan-novobiocin) agar. (nih.gov)
- An abbreviated procedure for the biochemical identification of Yersinia enterocolitica isolated from food enrichments on CIN (cefsulodin-irgasan-novobiocin) agar was investigated. (nih.gov)
- If Yersinia infection is suspected, the clinical laboratory should be notified and instructed to culture on cefsulodin-irgasan-novobiocin (CIN) or other specific for growing it. (cdc.gov)
- CDC recommends the use of cefsulodin-irgasan-novobiocin (CIN) agar for isolation of Yersinia spp. (cdc.gov)
- Die Stuhlproben wurden dafür im Direktausstrich auf dem Yersinia selektiven Cefsulodin-Irgasan-Novobiocin-Nährboden (CIN) für 24 h bei 37°C kultiviert. (uni-muenchen.de)
- Under the low-power magnification of 10X, using a digital Keyence scope, this photograph depicts the colonial growth displayed by Gram-negative, Yersinia pseudotuberculosis bacteria, which were cultured on a Cefsulodin-Irgasan-Novobiocin (CIN) agar medium, for a 24-hour time period, at a temperature of 37 ° C. (cdc.gov)
Cephalosporins1
- Expression of bla OXA-46 in Escherichia coli decreased susceptibility to penicillins and narrow-spectrum cephalosporins but not to extended-spectrum cephalosporins, cefsulodin, aztreonam, or carbapenems. (elsevier.com)
Pseudomonas4
- used cefsulodin sodium from TOKU-E to study the mechanisms of resistance in cefsulodin-resistant Pseudomonas aeruginosa . (toku-e.com)
- Cefsulodin sodium has a very limited spectrum specifically targeting Pseudomonas aeruginosa . (toku-e.com)
- Cefsulodin sodium is commonly used in clinical in vitro microbiological antimicrobial susceptibility tests (panels, discs, and MIC strips) primarily against Pseudomonas aeruginosa isolates. (toku-e.com)
- Study of combined therapy of tobramycin-cefsulodin-fosfomycin for respiratory tract infections caused by Pseudomonas aeruginosa. (nii.ac.jp)
Agar for isolation1
- Our Aeromonas Selective Blood Agar should modified cefsulodin-irgasan-novobiocin agar for isolation of Aeromonas spp FC, Yolken RH. (abp-tv.com)
Antibiotic3
- Under the tireless gaze of their time-lapse microscope, the researchers grew E. coli cells dosed with the antibiotic cefsulodin. (stanford.edu)
- After adding cefsulodin and letting the rod-shaped E. coli reproduce to become shapeless L-forms, they once again flushed out the antibiotic. (stanford.edu)
- Deletion of csiV, like deletion of lpoA or the PBP1A-encoding gene mrcA, causes cells to lose their rod shape in the presence of DAA or the beta-lactam antibiotic cefsulodin, and all three mutations are synthetically lethal with deletion of mrcB, which encodes PBP1B, V. cholerae's second key bifunctional PBP. (sigmaaldrich.com)
19851
- TAP Pharmaceuticals had a new drug application on file with FDA for cefsulodin under the brand name Cefonomil as of 1985. (wikipedia.org)
Cefixime1
- It differed from the elyA PCR product in restriction fragments generated by Alu I, Eco RI, and Mlu I. Of the 95 representative STEC strains, 88 produced hemolysin on blood agar supplemented with vancomycin (30 mg/liter), cefixime (20 μg/liter), and cefsulodin (3 mg/liter) (BVCC). (asm.org)
Selective2
- Partially selective media containing antimicrobial cocktails have been proposed in order to facilitate Y. enterocolitica recovery from fecal specimens, and the semiselective cefsulodin-irgasan-novobiocin (CIN) agar developed by Schiemann more than 30 years ago ( 9 ) is still the medium most widely used by medical microbiologists for this purpose. (asm.org)
- blood agar supplemented with ampicillin and a selective media, CIN (cefsulodin-irgasan-novobioci) agar, were used. (cdc.gov)
Solution5
- Cefsulodin 0.5mg/mL solution was observed to not degrade over a 4 day span at room temperature. (toku-e.com)
- With light additional heating (35°C, 1 hour) the cefsulodin powder didn't degrade while the solution showed slight degradation. (toku-e.com)
- Additional heating (35°C, 5 hours) of the solution yielded 6% of degradation of Cefsulodin solution. (toku-e.com)
- Aseptically add 1.2 mL of a sterile 10 mg/mL solution of Cefsulodin and mix well. (neogen.com)
- Moreover, it has been reported that carbenicillin ( 1 , 8 , 10 ), ticarcillin ( 10 ), cefsulodin ( 5 ), moxalactam ( 8 , 9 ), and ceftibuten ( 20 ) may isomerize in the body as well as in aqueous solution. (asm.org)
Acid1
- Recently, TOKU-E has found that the main cause of cefsulodin instability stems from one key impurity in 7-ACA (7-aminocephalosporanic acid- a raw material used in the synthesis of cefsulodin). (toku-e.com)
Data1
- Cefsulodin Sodium (CAS 52152-93-9) Market Research Report 2018 aims at providing comprehensive data on cefsulodin sodium market globally and regionally (Europe, Asia, North America, Latin America etc. (marketpublishers.com)
Medium1
- Based on a comparative analysis of 1,494 consecutive stools from hospitalized patients, CAY was found to be just as sensitive as the reference medium (cefsulodin-irgasan-novobiocin agar) but was significantly more specific and had a very low false-positive rate. (asm.org)
Publications2
- This graph shows the total number of publications written about "Cefsulodin" by people in Harvard Catalyst Profiles by year, and whether "Cefsulodin" was a major or minor topic of these publication. (harvard.edu)
- Below are the most recent publications written about "Cefsulodin" by people in Profiles. (harvard.edu)
Research2
- Cefsulodin Sodium (CAS 52152-93-9) Market Research Report 2018 contents were worked out and placed on the website in February, 2018. (marketpublishers.com)
- Please note that Cefsulodin Sodium (CAS 52152-93-9) Market Research Report 2018 is a half ready publication and contents are subject to change. (marketpublishers.com)
Market1
- It captures cefsulodin sodium market trends, pays close attention to cefsulodin sodium manufacturers and names suppliers. (marketpublishers.com)
Prices1
- Besides, the report provides cefsulodin sodium prices in regional markets. (marketpublishers.com)
Report1
- In addition to the above the report determines cefsulodin sodium consumers. (marketpublishers.com)
High1
- Compared to the wild type, bqsS and bqsR deletion mutants are sensitive to high levels of Fe(II), produce less spermidine in high Fe(II), and are more sensitive to tobramycin and polymyxin B but not arsenate, chromate, or cefsulodin. (caltech.edu)
Hours1
- The bioengineers let the L-forms grow and reproduce for a few hours before flushing out the cefsulodin. (stanford.edu)
Recovery1
- Six-hour urine recovery revealed 73.2% of the administered dose with a corresponding cefsulodin urinary clearance of 75.1 ml/min. (curehunter.com)