Cefotetan: A semisynthetic cephamycin antibiotic that is administered intravenously or intramuscularly. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative microorganisms.Cephamycins: Naturally occurring family of beta-lactam cephalosporin-type antibiotics having a 7-methoxy group and possessing marked resistance to the action of beta-lactamases from gram-positive and gram-negative organisms.Cefmetazole: A semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms. It has a high rate of efficacy in many types of infection and to date no severe side effects have been noted.Cefoxitin: A semisynthetic cephamycin antibiotic resistant to beta-lactamase.Cefoperazone: Semisynthetic broad-spectrum cephalosporin with a tetrazolyl moiety that is resistant to beta-lactamase. It has been proposed especially against Pseudomonas infections.Colorectal Surgery: A surgical specialty concerned with the diagnosis and treatment of disorders and abnormalities of the COLON; RECTUM; and ANAL CANAL.Bacteroides fragilis: Gram-negative bacteria occurring in the lower intestinal tracts of man and other animals. It is the most common species of anaerobic bacteria isolated from human soft tissue infections.Bacteria, AnaerobicDictionaries, MedicalDictionaries as Topic: Lists of words, usually in alphabetical order, giving information about form, pronunciation, etymology, grammar, and meaning.Dictionaries, ChemicalGram-Negative Bacteria: Bacteria which lose crystal violet stain but are stained pink when treated by Gram's method.beta-Lactamases: Enzymes found in many bacteria which catalyze the hydrolysis of the amide bond in the beta-lactam ring. Well known antibiotics destroyed by these enzymes are penicillins and cephalosporins.Cephalosporins: A group of broad-spectrum antibiotics first isolated from the Mediterranean fungus ACREMONIUM. They contain the beta-lactam moiety thia-azabicyclo-octenecarboxylic acid also called 7-aminocephalosporanic acid.Anti-Bacterial Agents: Substances that reduce the growth or reproduction of BACTERIA.Marketing: Activity involved in transfer of goods from producer to consumer or in the exchange of services.Research Report: Detailed account or statement or formal record of data resulting from empirical inquiry.Foundations: Organizations established by endowments with provision for future maintenance.Dietetics: The application of nutritional principles to regulation of the diet and feeding persons or groups of persons.Journalism, Medical: The collection, writing, and editing of current interest material on topics related to biomedicine for presentation through the mass media, including newspapers, magazines, radio, or television, usually for a public audience such as health care consumers.Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.Warfarin: An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.Drug Interactions: The action of a drug that may affect the activity, metabolism, or toxicity of another drug.Kinetics: The rate dynamics in chemical or physical systems.Wounds, Penetrating: Wounds caused by objects penetrating the skin.Neck Injuries: General or unspecified injuries to the neck. It includes injuries to the skin, muscles, and other soft tissues of the neck.Hydropneumothorax: A collection of fluid and gas within the pleural cavity. (Dorland, 27th ed)Wounds, Nonpenetrating: Injuries caused by impact with a blunt object where there is no penetration of the skin.Wounds, Stab: Penetrating wounds caused by a pointed object.Wounds, Gunshot: Disruption of structural continuity of the body as a result of the discharge of firearms.Neck: The part of a human or animal body connecting the HEAD to the rest of the body.Cefamandole: Semisynthetic wide-spectrum cephalosporin with prolonged action, probably due to beta-lactamase resistance. It is used also as the nafate.Microbial Sensitivity Tests: Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).Encyclopedias as Topic: Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)Penicillinase: A beta-lactamase preferentially cleaving penicillins. (Dorland, 28th ed) EC 3.5.2.-.Lactams: Cyclic AMIDES formed from aminocarboxylic acids by the elimination of water. Lactims are the enol forms of lactams.Cyclacillin: A cyclohexylamido analog of PENICILLANIC ACID.Carbapenems: A group of beta-lactam antibiotics in which the sulfur atom in the thiazolidine ring of the penicillin molecule is replaced by a carbon atom. THIENAMYCINS are a subgroup of carbapenems which have a sulfur atom as the first constituent of the side chain.Patents as Topic: Exclusive legal rights or privileges applied to inventions, plants, etc.Foramen Ovale, Patent: A condition in which the FORAMEN OVALE in the ATRIAL SEPTUM fails to close shortly after birth. This results in abnormal communications between the two upper chambers of the heart. An isolated patent ovale foramen without other structural heart defects is usually of no hemodynamic significance.Search Engine: Software used to locate data or information stored in machine-readable form locally or at a distance such as an INTERNET site.Device Approval: Process that is gone through in order for a device to receive approval by a government regulatory agency. This includes any required preclinical or clinical testing, review, submission, and evaluation of the applications and test results, and post-marketing surveillance. It is not restricted to FDA.Substance-Related Disorders: Disorders related to substance abuse.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.Inhalant Abuse: Illicit use of chemicals and products whose vapors can be inhaled to produce a rapid mind-altering effect. Inhalants include aerosols, gases, and volatile solvents that are often inhaled repeatedly to achieve the short-lived intoxicating effect.Marijuana Abuse: The excessive use of marijuana with associated psychological symptoms and impairment in social or occupational functioning.Equipment Design: Methods of creating machines and devices.Cholera Vaccines: Vaccines or candidate vaccines used to prevent infection with VIBRIO CHOLERAE. The original cholera vaccine consisted of killed bacteria, but other kinds of vaccines now exist.Cholera: An acute diarrheal disease endemic in India and Southeast Asia whose causative agent is VIBRIO CHOLERAE. This condition can lead to severe dehydration in a matter of hours unless quickly treated.Vaccines: Suspensions of killed or attenuated microorganisms (bacteria, viruses, fungi, protozoa), antigenic proteins, synthetic constructs, or other bio-molecular derivatives, administered for the prevention, amelioration, or treatment of infectious and other diseases.Physician-Patient Relations: The interactions between physician and patient.Vaccines, Inactivated: Vaccines in which the infectious microbial nucleic acid components have been destroyed by chemical or physical treatment (e.g., formalin, beta-propiolactone, gamma radiation) without affecting the antigenicity or immunogenicity of the viral coat or bacterial outer membrane proteins.Cholera Toxin: An ENTEROTOXIN from VIBRIO CHOLERAE. It consists of two major protomers, the heavy (H) or A subunit and the B protomer which consists of 5 light (L) or B subunits. The catalytic A subunit is proteolytically cleaved into fragments A1 and A2. The A1 fragment is a MONO(ADP-RIBOSE) TRANSFERASE. The B protomer binds cholera toxin to intestinal epithelial cells, and facilitates the uptake of the A1 fragment. The A1 catalyzed transfer of ADP-RIBOSE to the alpha subunits of heterotrimeric G PROTEINS activates the production of CYCLIC AMP. Increased levels of cyclic AMP are thought to modulate release of fluid and electrolytes from intestinal crypt cells.Phytotherapy: Use of plants or herbs to treat diseases or to alleviate pain.

Cross-reactivity of cefotetan and ceftriaxone antibodies, associated with hemolytic anemia, with other: cephalosporins and penicillin. (1/39)

Most drug-induced immune hemolytic anemias since the late 1980s have been caused by the second- and third-generation cephalosporins, cefotetan and ceftriaxone, respectively. Cross-reactivity of cefotetan and ceftriaxone antibodies with other cephalosporins or penicillin has been studied only minimally. We tested 7 serum samples previously identified to contain cefotetan antibodies and one serum sample previously identified to contain ceftriaxone antibodies against 9 other cephalosporins, penicillin, and 7-aminocephalosporanic acid in the presence of RBCs and also used hapten inhibition to indicate cross-reactivity. Serum samples containing cefotetan antibodies showed some cross-reactivity with cephalothin and cefoxitin (and to a much lesser extent with penicillin and ceftazidime). The ceftriaxone antibodies showed very weak cross-reactivity with cefotaxime, cefamandole, and cefoperazone. There was very little cross-reactivity between cefotetan antibodies and the drugs tested in the present study. We have no data to determine whether the in vitro data relate to in vivo reactivity.  (+info)

Fitz-Hugh-Curtis syndrome: a diagnosis to consider in women with right upper quadrant pain. (2/39)

Fitz-Hugh-Curtis syndrome--inflammation of the liver capsule associated with genital tract infection--occurs in up to one fourth of patients with pelvic inflammatory disease (PID). Classically presenting as sharp, pleuritic right upper quadrant pain, usually but not always accompanied by signs of salpingitis, it can mimic many other common disorders such as cholecystitis and pyelonephritis.  (+info)

Pharmacokinetics and tissue penetration of single-dose cefotetan used for antimicrobial prophylaxis in patients undergoing colorectal surgery. (3/39)

The pharmacokinetics and tissue penetration of cefotetan were studied after a single injection of 2 g given intravenously for antimicrobial prophylaxis to 16 consecutive patients undergoing colorectal surgery. Concentrations in tissue greater than or equal to the MIC for 90% of the main pathogens tested were considered adequate. The elimination half-life at beta phase was 4.6 +/- 1.4 h, the total body clearance was 0.75 +/- 0.19 ml/kg/min, and the volume of distribution was 260 +/- 71 ml/kg. At the time of incision (33 +/- 16 min after the injection), cefotetan concentrations were 14.2 +/- 7 micrograms/g in abdominal-wall fat, 16.4 +/- 1 micrograms/g in epiploic fat, and 163 +/- 62 mg/liter in serum. At the time of surgical anastomosis (151 +/- 54 min), cefotetan concentrations were 33.3 +/- 6 micrograms/g in the colonic wall and 73 +/- 34 mg/liter in serum. Upon closure of the abdomen (216 +/- 76 min), cefotetan concentrations were 6.3 +/- 3 micrograms/g in abdominal-wall fat, 6.1 +/- 4 micrograms/g in epiploic fat, and 64 +/- 38 mg/liter in serum. Cefotetan tissue penetration was 10% into abdominal and epiploic fat and 46% into the colonic wall. Levels in tissue were compared with the MIC for 90% of the most frequently encountered pathogenic germs (Staphylococcus aureus, Bacteroides fragilis, and Escherichia coli). Adequate concentrations in tissue were obtained up to anastomosis but not upon closure. The authors therefore recommend the injection of an additional dose of 1 g before closure in order to ensure optimal efficacy throughout the surgical procedure.  (+info)

Evaluation of beta-lactamase inhibitors in disk tests for detection of plasmid-mediated AmpC beta-lactamases in well-characterized clinical strains of Klebsiella spp. (4/39)

The diagnostic utility of the AmpC beta-lactamase inhibitors LN-2-128, 48-1220, and Syn 2190 in combination with cefotetan (CTT) or cefoxitin in a disk test for the detection of clinical isolates of Klebsiella spp. producing plasmid-mediated AmpC beta-lactamases (pAmpCs) was evaluated. The combination of Syn 2190 and CTT had a sensitivity of 91%, a specificity of 100%, and a reproducibility of 100% and showed the best potential of using an inhibitor for detection of Klebsiella spp. producing pAmpCs.  (+info)

Radiation recall dermatitis with cefotetan: a case study. (5/39)

Radiation recall dermatitis (RRD) is an inflammatory skin reaction that occurs in a previously irradiated body part following drug administration. This phenomenon may occur from days to years following exposure to ionizing radiation. The case of a 54-year-old Caucasian woman who was initially treated with external-beam radiation to the right thoracic region following the diagnosis of a poorly differentiated squamous cell carcinoma of the right lung is reported. She received four cycles of consolidated chemotherapy with docetaxel and carboplatin. Four months later, she was admitted to the hospital for acute cholecystitis and was placed on cefotetan. She developed a tender, erythematous rash on the posterior region of her right thorax 48 hours later. The drug was withdrawn, supportive care was instituted, and the patient subsequently improved. RRD should be suspected in patients who develop an erythematous rash in a previously irradiated region. To our knowledge this entity has not been associated with cefotetan previously.  (+info)

Ertapenem versus cefotetan prophylaxis in elective colorectal surgery. (6/39)

BACKGROUND: Ertapenem, a long-acting carbapenem, may be an alternative to the recommended prophylactic antibiotic cefotetan. METHODS: In this randomized, double-blind trial, we assessed the efficacy and safety of antibiotic prophylaxis with ertapenem, as compared with cefotetan, in patients undergoing elective colorectal surgery. A successful outcome was defined as the absence of surgical-site infection, anastomotic leakage, or antibiotic use 4 weeks postoperatively. All adverse events were collected until 14 days after the administration of antibiotic prophylaxis. RESULTS: Of the 1002 patients randomly assigned to study groups, 901 (451 in the ertapenem group and 450 in the cefotetan group) qualified for the modified intention-to-treat analysis, and 672 (338 in the ertapenem group and 334 in the cefotetan group) were included in the per-protocol analysis. After adjustment for strata, in the modified intention-to-treat analysis, the rate of overall prophylactic failure was 40.2% in the ertapenem group and 50.9% in the cefotetan group (absolute difference, -10.7%; 95% confidence interval [CI], -17.1 to -4.2); in the per-protocol analysis, the failure rate was 28.0% in the ertapenem group and 42.8% in the cefotetan group (absolute difference, -14.8%; 95% CI, -21.9 to -7.5). Both analyses fulfilled statistical criteria for the superiority of ertapenem. In the modified intention-to-treat analysis, the most common reason for failure of prophylaxis in both groups was surgical-site infection: 17.1% in the ertapenem group and 26.2% in the cefotetan group (absolute difference, -9.1; 95% CI, -14.4 to -3.7). In the treated population, the overall incidence of Clostridium difficile infection was 1.7% in the ertapenem group and 0.6% in the cefotetan group (P=0.22). CONCLUSIONS: Ertapenem is more effective than cefotetan in the prevention of surgical-site infection in patients undergoing elective colorectal surgery but may be associated with an increase in C. difficile infection. (ClinicalTrials.gov number, NCT00090272 [ClinicalTrials.gov].).  (+info)

Interpretive criteria and quality control guidelines for Neisseria gonorrhoeae susceptibility test standardization for cefotetan. (7/39)

Cefotetan was tested in a multilaboratory study to standardize susceptibility testing criteria and quality control guidelines for Neisseria gonorrhoeae. Cefotetan was most active against penicillinase-producing and penicillin-susceptible strains (MIC for 50% of strains tested, 0.5 micrograms/ml) and was least active against the chromosomally resistant isolates (MIC for 50% of strains tested, 2 micrograms/ml). The recommended 30-micrograms disk cefotetan interpretive criteria were as follows: susceptible at greater than or equal to 26 mm (less than or equal to 2 micrograms/ml), intermediate at 20 to 25 mm (4 micrograms/ml), and resistant at less than or equal to 19 mm (greater than or equal to 8 micrograms/ml). Quality control guidelines for agar dilution and disk diffusion tests were established by using numerous GC agar lots, three cefotetan 30-micrograms disk lots, two quality control organisms, and a volume of tests consistent with National Committee for Clinical Laboratory Standards M23-T guidelines.  (+info)

Antibiotic treatment and associated prolonged prothrombin time. (8/39)

The incidence and type of pathology causing a prolonged prothrombin time and clinical bleeding episodes were assessed in a multicentre study of 1109 patients receiving cefotetan, a N-methyl-thiotetrazole (NMTT), or equivalent antibiotics. There was no significant difference in the incidence of a prolonged prothrombin time (9.9% with cefotetan, 8.0% with comparable antibiotics) of clinical bleeding episodes. However, prothrombin time increases of greater than 12 seconds were significantly (p = 0.002) greater with cefotetan (3.8%) than with comparators (0.8%). In both antibiotic groups increases in prothrombin time were more likely following surgery and in patients who were older, with a high platelet count, low albumin, or higher urea and creatinine concentrations. All antibiotic treatment can be associated with prolonged prothrombin times and new agents should always be assessed in a large multicentre study before the practical, clinical importance of haemostatic defects can be defined.  (+info)

*Cefotetan

... has a broad spectrum of activity and has been used to treat bacterial infections of the bone, skin, urinary tract, ... Cefotetan was developed by Yamanouchi. It is marketed outside Japan by AstraZeneca with the brand names Apatef and Cefotan. The ... Cefotetan is an injectable antibiotic of the cephamycin type for prophylaxis and treatment of bacterial infections. It is often ... "Cefotetan Susceptibility and Minimum Inhibitory Concentration (MIC) Data" (PDF). Toku-e. Cefotan official web site run by ...

*Beta-lactamase

Cephamycins (cefoxitin and cefotetan) are not hydrolyzed by majority of ESBLs, but are hydrolyzed by associated AmpC-type β- ... cefoxitin and cefotetan); has been blocked by inhibitors such as clavulanate, sulbactam, or tazobactam, and did not involve ... cefotetan) but resistance to the third-generation cephalosporins and to aztreonam. Moreover, one should suspect these strains ... such as cefoxitin or cefotetan are not affected by commercially available β-lactamase inhibitors, and can, in strains with loss ...

*Radiation burn

Ayoola, A.; Lee, Y. J. (2006). "Radiation recall dermatitis with cefotetan: a case study" (pdf). The Oncologist. 11 (10): 1118- ...

*Cephamycin

... s include: Cefoxitin Cefotetan Cefmetazole Oreste A. Mascaretti (2003). Bacteria Versus Antibacterial Agents: An ... Clarke AM, Zemcov SJ (January 1983). "Antibacterial activity of the cephamycin cefotetan: an in-vitro comparison with other ...

*Cephalosporin

These include latamoxef (moxalactam), cefmenoxime, cefoperazone, cefamandole, cefmetazole, and cefotetan. This is thought to be ... and cefotetan are classed as second-generation cephalosporins. Cefmetazole and cefoxitin are classed as third-generation ...

*Pelvic inflammatory disease

Typical regimens include cefoxitin or cefotetan plus doxycycline, and clindamycin plus gentamicin. An alternative parenteral ...

*Tubal factor infertility

Typical antibiotics used are cefoxitin or cefotetan plus doxycycline, and clindamycin plus gentamicin. An alternative ...

*Drug-induced autoimmune hemolytic anemia

Cefotetan-dependent hemolytic anemia mimicking an acute intravascular immune transfusion reaction". American Journal of ...

*Doxycycline

... comparison of cefotetan plus doxycycline and ana doxycycline". Am. J. Obstet. Gynecol. 158 (3 Pt 2): 736-41. PMID 3162653. ...

*Peritonitis

Out of the cephalosporins, cefoxitin and cefotetan can be used to cover gram positive bacteria, gram negative bacteria, and ...

*Anaerobic infection

Agents no longer recommended are: cefotetan and clindamycin ( Bacteroides fragilis group resistance) and ampicillin-sulbactam ( ...

*Wolfgang Klietmann

Klietmann, W; Focht, J; Nösner, K (1987). "Comparative in vitro study of the antibacterial effect of cefotetan against gram- ...

*Warm antibody autoimmune hemolytic anemia

... such as ceftriaxone and cefotetan), and ciprofloxacin. The most common antibody isotype involved in warm antibody AIHA is IgG, ...

*List of MeSH codes (D03)

... cefotetan MeSH D03.383.129.617.467 --- losartan MeSH D03.383.129.617.700 --- tetrazolium salts MeSH D03.383.129.617.700.500 ...

*AstraZeneca

... cefotetan) Avloclor (chloroquine) Cubicin (daptomycin) Foscavir (foscarnet) Lexinor (norfloxacin) Merrem/Meronem (meropenem) ...

*List of β-lactam antibiotics

Cefotetan Cefoxitin Cefixime Cefotaxime Cefpodoxime Ceftazidime Ceftriaxone (With β-lactamase stability and enhanced activity ...

*List of MeSH codes (D02)

... cefotetan MeSH D02.065.589.099.249.250.222 --- cefoxitin MeSH D02.065.589.099.374 --- clavulanic acids MeSH D02.065.589.099. ...

*Disulfiram-like drug

... cefotetan, ceftriaxone, cefuroxime, and latamoxef (moxalactam); thought to be due to common N-methylthiotetrazole metabolite ...

*List of drugs: Cb-Ce

... cefotetan (INN) cefotiam (INN) cefovecin sodium (USAN) cefoxazole (INN) cefoxitin (INN) cefozopran (INN) cefpimizole (INN) ...

*Disulfiram

... cefamandole and cefotetan, that have a N-methylthio-tetrazole moiety Griseofulvin, an oral antifungal drug Procarbazine ...

*ATC code J01

Cefroxadine J01DB12 Ceftezole J01DC01 Cefoxitin J01DC02 Cefuroxime J01DC03 Cefamandole J01DC04 Cefaclor J01DC05 Cefotetan ...

*Timeline of antibiotics

... cefotetan 1984 - temocillin 1985 - cefpiramide 1985 - imipenem/cilastatin, the first carbapenem 1985 - ofloxacin 1986 - ...
... is a type of injection given to treat or prevent certain bacterial infections. This page from the eMedTV site takes a look at a number of topics related to this prescription antibiotic, including how it works, how it is given, and side effects.
As detailed in this selection from the eMedTV Web library, cefotetan can interact with warfarin, probenecid, and other drugs. This article explains how you can reduce your risk of interactions and lists other products that can cause problems.
A semisynthetic cephamycin antibiotic that is administered intravenously or intramuscularly. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative microorganisms ...
Provides information on usage, precautions, side effects and brand names when available. Data provided by various government agencies and health-related organizations. ...
CEPHALOSPORINS. The first-generation cephalosporins represented by the oral drugs cephalexin and cefadroxil, and the injectable drug cefazolin have a spectrum of activity that includes staphylococci, streptococci, and many of the enteric gram-negative bacilli. However, resistance among gram-negative bacteria develops easily, primarily from synthesis of ß-lactamase enzymes that can hydrolyze these drugs. Extended-spectrum cephalosporins include those from the 2nd, 3rd, and 4th generation have been used in resistant infections caused by Escherichia coli, Klebsiella pneumoniae, Enterobacter species, Proteus species (especially indole-positive), and Pseudomonas aeruginosa. Of the 2nd-generation cephalosporins, the ones used most often in veterinary medicine are cefoxitin and cefotetan. Their use has been valuable for treating organisms resistant to the 1st generation cephalosporins or in cases in which there are anaerobic bacteria present. Anaerobic bacteria such as those of the Bacteroides ...
This page includes the following topics and synonyms: Second Generation Anti-anaerobe Cephalosporins, Cefoxitin, Cefotetan, Cefamandole.
351 medications are known to interact with Sensorcaine with Epinephrine. Includes Ancef (cefazolin), Cefotan (cefotetan), cephalexin.
HealthTap: Doctor answers on Symptoms, Diagnosis, Treatment, and More: Dr. Khanna on what antibiotics treat boils: Parentral Treat regimen 1 Cefotetan 2gm/12hrs or Cefioxitin 2gm/6hrs plus Doxycycline100 mgm/12 hrs orally Parentral Regimen 2 Clindamycine900mgm/8 hrs plus Gentamycine loading dose 2mgm/kgm body weight followed by maintanance of 1.5mgm/kgm every 8hours Regimen3 Ampi/sublactam3gm/8hrs plus Doxy100mgm/12hrs Oral Flagyl500mgm/2times for14days plus Doxy100mgm/12hr plus Ceftrioxon250mgm dose
Looking for online definition of cefotetan in the Medical Dictionary? cefotetan explanation free. What is cefotetan? Meaning of cefotetan medical term. What does cefotetan mean?
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Merck & Co., Inc. announced today that the U.S. Food and Drug Administration (FDA) recently approved INVANZÃ ® (ertapenem), a once-daily injectable antibiotic, for the prophylaxis of surgical site infection (SSI) following elective colorectal surgery in adults. This approval was based upon the results of the landmark PREVENT trial, the largest prospective, randomized double-blind, comparative clinical trial ever conducted in antibiotic prophylaxis for elective colorectal surgery (N=1002). Results from the study were presented today in the New England Journal of Medicine. "Given the high incidence of SSI, Merck is very pleased to be able to offer a new alternative with clinically demonstrated efficacy," said Murray A. Abramson, M.D., M.P.H., senior medical director, Merck Research Labs, Infectious Diseases, Merck & Co. Inc. In the PREVENT study, a statistically significant difference favoring INVANZ over cefotetan with respect to the primary endpoint has been observed. A second adequate and ...
Warfarin has been reported to interact with more than 100 drugs, including many antibiotics. Warfarin is a racemic mixture of S- and R-warfarin enantiomers. S-warfarin is considered to have several times more anticoagulant activity than R-warfarin. S-warfarin is primarily metabolized by CYP2C9, whereas Rwarfarin is metabolized by CYP1A2, CYP2C19, and CYP3A4. Thus, one would expect that drugs inhibiting CYP2C9, and therefore S-warfarin metabolism, would increase the concentration of warfarin and enhance its anticoagulant effect (Table). Other antibiotics have been reported to increase warfarin response. Some?such as moxalactam, cefoperazone, cefamandole, cefotetan, and cefmetazole?appear to inhibit the formation of clotting factors and indirectly increase the effect of warfarin. As with the antibiotics that are inhibitors of CYP2C9, there may be a reasonable mechanism for these purported interactions. For the majority of antibiotics associated with warfarin interactions, however, there is no ...
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Taos [http://www.taoschamber.com] is a town in New Mexico in the United States, about a two hours drive from Santa Fe. It is noted for its art colony, skiing, and Taos Pueblo, a photogenic American Indian community that is open to visitors under controlled conditions. These attractions have made it a popular travel destination in recent years.
(anti-neoplastic drugs are not included) Quinine/Quinidine group Quinine Quinidine Heparin Regular unfractionated heparin Low molecular weight heparin Gold salts Antimicrobials Antimony containing drugs Stibophen Sodium stibogluconate Cephalosporins Cephamandazole Cefotetan Ceftazidime Cephalothin Ciprofloxacin Clarithromycin Fluconazole Fusidic acid Gentamicin Nilidixic acid Penicillins Ampicillin Apalcillin Methicillin Meziocillin Penicillin Piperacillin Pentamidine Rifampin Sulpha group Sulfamethoxazole Sulfamethoxypyridazine Sulfisoxazole Suramin Vancomycin…
Therapy Drug-drug interactions displayed by pressing [f3] while in the list of drugs will now display details of each interaction. The listings for drug toxicity and interactions have been extensively updated and expanded Drugs added Levofloxacin Pharmacological profile Ampicillin-sulbactam, Cefotetan, Doxycycline, Meningococcal vaccine, Ofloxacin, Pyrimethamine / sulfadoxine Susceptibility database Eubacterium lentum Testing criteria Levofloxaxin Interactions database Atorvastatin, Colestipol, Insulin, Molindone, Pirenzepine, Zalcitabine Microbiology Note: A variety of fermentation and other reactions for gram-positive bacilli and non-fermentative gram-negative bacilli may require three or more days. The GIDEON data base allows for delayed positivity in such cases. Therefore, do not indicate a negative response for such organisms until at least three days have passed (see individual notes [F2] in the identification module). New taxa added Achromobacter group B, Achromobacter group E, ...
As recently reviewed, 1026 neuroprotective drug candidates in stroke research have all failed on their road towards validation and clinical translation, reasons being quality issues in preclinical research and publication bias. Quality control guidelines for preclinical stroke studies have now been established. However, sufficient understanding of the underlying mechanisms of neuronal death after stroke that could be possibly translated into new therapies is lacking. One exception is the hypothesis that cellular death is mediated by oxidative stress. Oxidative stress is defined as an excess of reactive oxygen species (ROS) derived from different possible enzymatic sources. Among these, NADPH oxidases (NOX1-5) stand out as they represent the only known enzyme family that has no other function than to produce ROS. Based on data from different NOX knockout mouse models in ischemic stroke, the most relevant isoform appears to be NOX4. Here we discuss the state-of-the-art of this target with respect ...
Ertapenem was evaluated in adults for the treatment of acute pelvic infections in a clinical trial. This study compared ertapenem (1 g intravenously once a day) with piperacillin/tazobactam (3.375 g intravenously every 6 hours) for 3 to 10 days and enrolled 412 patients including 350 patients with obstetric/postpartum infections and 45 patients with septic abortion. The clinical success rates in the clinically evaluable population at 2 to 4 weeks posttherapy (test-of-cure) were 93.9% (153/163) for ertapenem and 91.5% (140/153) for piperacillin/tazobactam.. Prophylaxis of Surgical Site Infections Following Elective Colorectal Surgery. Ertapenem was evaluated in adults for prophylaxis of surgical site infection following elective colorectal surgery in a multicenter, randomized, double-blind clinical trial. This study compared a single intravenous dose of ertapenem (1 g) versus cefotetan (2 g) administered over 30 minutes, 1 hour before elective colorectal surgery. Test-of-prophylaxis was defined ...
Klebsiella pneumoniae isolates from 11 patients at the Miriam Hospital were identified as resistant to cefoxitin and ceftibuten as well as to aztreonam, cefotaxime, and ceftazidime. Resistance could be transferred by conjugation or transformation with plasmid DNA into Escherichia coli and was due to the production of a beta-lactamase with an isoelectric point of 8.4 named MIR-1. In E. coli, MIR-1 conferred resistance to aztreonam, cefotaxime, ceftazidime, ceftibuten, ceftriaxone, and such alpha-methoxy beta-lactams as cefmetazole, cefotetan, cefoxitin, and moxalactam. In vitro, MIR-1 hydrolyzed cephalothin and cephaloridine much more rapidly than it did penicillin G, ampicillin, or carbenicillin. Cefotaxime was hydrolyzed at 10% the rate of cephaloridine. Cefoxitin inactivation could only be detected by a microbiological test. The inhibition profile of MIR-1 was similar to that of chromosomally mediated class I beta-lactamases. Potassium clavulanate had little effect on cefoxitin or cefibuten ...
Warm antibody autoimmune hemolytic anemia (WAIHA) is the most common form of autoimmune hemolytic anemia. About half of the cases are of unknown cause, with the other half attributable to a predisposing condition or medications being taken. Contrary to cold autoimmune hemolytic anemia (e.g., cold agglutinin disease and paroxysmal cold hemoglobinuria) which happens in cold temperature (28-31 °C), WAIHA happens at body temperature. AIHA may be: Idiopathic, that is, without any known cause Secondary to another disease, such as an antecedent upper respiratory tract infection, systemic lupus erythematosus or a malignancy, such as chronic lymphocytic leukemia (CLL) Several medications have been associated with the development of warm AIHA. These medications include quinidine, nonsteroidal anti-inflammatory drugs (NSAIDs), alpha methyldopa, and antibiotics such as penicillins, cephalosporins (such as ceftriaxone and cefotetan), and ciprofloxacin. The most common antibody isotype involved in warm ...
PubMed Central Canada (PMC Canada) provides free access to a stable and permanent online digital archive of full-text, peer-reviewed health and life sciences research publications. It builds on PubMed Central (PMC), the U.S. National Institutes of Health (NIH) free digital archive of biomedical and life sciences journal literature and is a member of the broader PMC International (PMCI) network of e-repositories.
Learn all about the common causes of foot pain and ankle injuries and how best to treat them. Includes injuries, tendonitis, swelling and plantar fasciitis.
Results:. An outbreak of C. difficile-associated diarrhea was caused by a clonal isolate of clindamycin-resistant C. difficile and was associated with increased use of clindamycin. Hospital-wide requirement of approval by an infectious disease consultant of clindamycin use led to an overall reduction in clindamycin use, a sustained reduction in the mean number of cases of C. difficile-associated diarrhea (11.5 cases/month compared with 3.33 cases/month; P , 0.001), and an increase in clindamycin susceptibility among C. difficile isolates (9% compared with 61%; P , 0.001). A parallel increase was noted in the use of and costs associated with other antibiotics with antianaerobic activity, including cefotetan, ticarcillin-clavulanate, and imipenem-cilastin. The hospital realized overall cost savings as a result of the decreased incidence of C. difficile-associated diarrhea. ...
Infectious morbidity for the mother, consisting primarily of endomyometritis and wound infection remains a leading cause of post operative complications. Infectious morbidity following CD remains among the top five causes of mortality in mothers worldwide, causing a huge burden to the society [9].. In the study by Sullivan et al. [7], on 357 women, decreased total infectious morbidity in the study group was found (RR = 0.4, 95% CI = 0.18 to 0.87). There was a decreased endometritis risk as well in the pre incision group (RR = 0.2, 95% CI = 0.15 to 0.94).There was no increase in neonatal sepsis (P = 0.99), sepsis work up (P = 0.96) or increased hospital stay (P = 0.17). In the present study, the results were almost similar in that, the incidence of SSI was decreased and duration of hospital stay was decreased with antibiotics given Pre-incision than after cord clamping. Unlike the study by Sullivan et al. [7], in the present study, the incidence of endometritis was similar in both groups. ...
the relationship with her first husband deteriorated because he insisted she was not the same person. This change in personality is a frequent report by spouses of individuals who have sustained TBIs. According to her reports one night he tried to kill her. The anomalous phenomena began that night and have been intermittent since that time. Their intensity and frequency have increased during the last 2-3 years. The anomalous phenomena include mechanical, electronic, and visual effects. She reports experiences of sounds, perceived as taps that she estimates to be between 3 and 4 Hz with sound pressure equivalents between 40 and 60 db. Occasionally there may be a single louder sound. The durations of clusters are often between 3 and 10 seconds with intervening periods of 4-8 or 16-24 seconds. The clusters are usually localized along her left side.. . . .. Ms. S. reported she feels overwhelmed by a deep sadness after the occurrence of the phenomena and cries, even if nothing bad happens. ...
Methicillin-resistant Staphylococcus aureus (MRSA) strains are usually resistant to other classes of antimicrobials, namely, aminoglycosides, fluoroquinolones, macrolides, and tetracyclines (6, 8). β-Lactams also pose a unique therapeutic problem due to the ability of MRSA to produce penicillinase and a low-affinity target penicillin-binding protein, PBP 2a (6, 8). Thus, the therapeutic options for treating MRSA infections have been limited to glycopeptides, quinupristin-dalfopristin, or linezolid (1, 6, 8). The treatment of MRSA infections became even more complex due to the emergence of strains with decreased susceptibility to glycopeptides, thus increasing the need to develop novel antimicrobials to treat MRSA infections (4, 8).. BAL9141 (formerly Ro 63-9141) is a pyrrolidinone-3-ylidenemethyl cephalosporin which has a broad spectrum of antimicrobial activity; most notable is the potent activity against methicillin-resistant staphylococci (2, 5, 7). BAL9141 activity against MRSA is due to ...
The infective agent of CJD (the prion) is resistant to routine reprocessing (as defined in AS/NZS 4187 Cleaning, disinfecting and sterilizing reusable medical and surgical instruments and equipment, and maintenance of associated environments in health care facilities). This makes the additional procedures outlined in this document essential for treatment of patients with an identified risk of CJD infection. The decision to implement additional procedures for the reprocessing of certain instruments and equipment is based on the currently known infectivity of the tissue to which the instrument or equipment has been exposed (see Table 1) and patient risk factors (refer to Sections 2.3 and 2.4 and Appendices 1 and 2). Provided that the care of the patient is not compromised, alternative diagnostic and management strategies, if suitable and available, can be considered in patients at risk of CJD ...
SYDNEY (AFP) - Measles can be spread on planes in rows far beyond infected passengers, a Australian study showed on Wednesday, raising questions over control guidelines for the disease.. Read more at straitstimes.com.

Cefotetan - WikipediaCefotetan - Wikipedia

Cefotetan has a broad spectrum of activity and has been used to treat bacterial infections of the bone, skin, urinary tract, ... Cefotetan was developed by Yamanouchi. It is marketed outside Japan by AstraZeneca with the brand names Apatef and Cefotan. The ... Cefotetan is an injectable antibiotic of the cephamycin type for prophylaxis and treatment of bacterial infections. It is often ... "Cefotetan Susceptibility and Minimum Inhibitory Concentration (MIC) Data" (PDF). Toku-e. Cefotan official web site run by ...
more infohttps://en.wikipedia.org/wiki/Cefotetan

Cefotetan Injection: MedlinePlus Drug InformationCefotetan Injection: MedlinePlus Drug Information

Cefotetan Injection: learn about side effects, dosage, special precautions, and more on MedlinePlus ... Use cefotetan injection until you finish the prescription, even if you feel better. If you stop using cefotetan injection too ... Cefotetan injection is also used before surgery to prevent infections. Cefotetan injection is in a class of medications called ... Before using cefotetan injection,. *tell your doctor and pharmacist if you are allergic to cefotetan injection; other ...
more infohttps://medlineplus.gov/druginfo/meds/a686015.html

Cefotetan Na Kukje - Drugs.comCefotetan Na Kukje - Drugs.com

A list of US medications equivalent to Cefotetan Na Kukje is available on the Drugs.com website. ... Cefotetan Na Kukje is a medicine available in a number of countries worldwide. ... Ingredient matches for Cefotetan Na Kukje. Cefotetan. Cefotetan is reported as an ingredient of Cefotetan Na Kukje in the ... Cefotetan Na Kukje. Cefotetan Na Kukje may be available in the countries listed below. ...
more infohttps://www.drugs.com/international/cefotetan-na-kukje.html

Cefotetan - DrugBankCefotetan - DrugBank

Cefotetan is 88% plasma protein bound.. Metabolism. No active metabolites of cefotetan have been detected; however, small ... No active metabolites of cefotetan have been detected; however, small amounts (less than 7%) of cefotetan in plasma and urine ... Cefotetan 1 gm vial. 13.66USD vial. DrugBank does not sell nor buy drugs. Pricing information is supplied for informational ... Cefotetan disodium. 0GXP746VXB. 74356-00-6. ZQQALMSFFARWPK-GLHLDKNHSA-L. Prescription Products. Name. Dosage. Strength. Route. ...
more infohttps://www.drugbank.ca/drugs/DB01330

Cefotetan: Indications, Side Effects, Warnings - Drugs.comCefotetan: Indications, Side Effects, Warnings - Drugs.com

Easy-to-read patient leaflet for Cefotetan. Includes indications, proper use, special instructions, precautions, and possible ... What do I need to tell my doctor BEFORE I take Cefotetan?. *If you have an allergy to cefotetan or any other part of cefotetan ... How do I store and/or throw out Cefotetan?. *If you need to store cefotetan at home, talk with your doctor, nurse, or ... How is this medicine (Cefotetan) best taken?. Use cefotetan as ordered by your doctor. Read all information given to you. ...
more infohttps://www.drugs.com/cdi/cefotetan.html

Cefotetan: Pediatric Medication | Memorial Sloan Kettering Cancer CenterCefotetan: Pediatric Medication | Memorial Sloan Kettering Cancer Center

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.. ...
more infohttps://www.mskcc.org/cancer-care/patient-education/cefotetan

Apatef (Cefotetan Disodium) AstraZenecaApatef (Cefotetan Disodium) AstraZeneca

Apatef information about active ingredients, pharmaceutical forms and doses by AstraZeneca, Apatef indications, usages and related health products lists
more infohttp://drugs-about.com/drugs-a/apatef.html

Cefotetan Intravenous : Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMDCefotetan Intravenous : Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD

Find patient medical information for Cefotetan Intravenous on WebMD including its uses, side effects and safety, interactions, ... Cefotetan may cause live bacterial vaccines (such as typhoid vaccine) to not work as well. Do not have any immunizations/ ... Cefotetan is an antibiotic used to treat a wide variety of bacterial infections. It may also be used before and during certain ... Before using cefotetan, tell your doctor or pharmacist if you are allergic to it; or to other cephalosporins; or to penicillins ...
more infohttps://www.webmd.com/drugs/2/drug-18424/cefotetan-intravenous/details

Cefotetan (Injection Route) Description and Brand Names - Mayo ClinicCefotetan (Injection Route) Description and Brand Names - Mayo Clinic

Cefotetan injection is used to treat bacterial infections in many different parts of the body. This medicine is also given ... Cefotetan injection belongs to the class of medicines known as cephalosporin antibiotics. It works by killing bacteria or ...
more infohttps://www.mayoclinic.org/drugs-supplements/cefotetan-injection-route/description/drg-20073401

cefotetan Side Effects, Interactions, Uses & Drug Imprintcefotetan Side Effects, Interactions, Uses & Drug Imprint

Drug Information on cefotetan includes drug pictures, side effects, drug interactions, directions for use, symptoms of overdose ... Cefotetan is injected into a muscle or into a vein through an IV. You may be shown how to use injections at home. Do not give ... Cefotetan is usually given once every 12 hours for 5 to 10 days. Follow your doctors instructions very carefully. ... Cefotetan can pass into breast milk, but effects on the nursing baby are not known. Tell your doctor if you are breast-feeding. ...
more infohttps://www.emedicinehealth.com/drug-cefotetan/article_em.htm

Cefotetan (Cefotetan for Injection): Side Effects, Interactions, Warning, Dosage & UsesCefotetan (Cefotetan for Injection): Side Effects, Interactions, Warning, Dosage & Uses

Cefotetan for Injection) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and ... Cefotetan for Injection, USP. To reduce the development of drug-resistant bacteria and maintain the effectiveness of cefotetan ... Cefotetan for Injection, USP is supplied in a Pharmacy Bulk Package containing 80 mg (3.5 mEq) of sodium per gram of cefotetan ... Cefotetan is excreted in human milk in very low concentrations. Caution should be exercised when cefotetan is administered to a ...
more infohttps://www.rxlist.com/cefotetan-drug.htm

Cefotetan | definition of cefotetan by Medical dictionaryCefotetan | definition of cefotetan by Medical dictionary

... cefotetan explanation free. What is cefotetan? Meaning of cefotetan medical term. What does cefotetan mean? ... Looking for online definition of cefotetan in the Medical Dictionary? ... cefotetan. Also found in: Wikipedia. cefotetan. [sef´o-te″tan] a β-lactamase-resistant second-generation cephalosporin ... Cefotetan , definition of cefotetan by Medical dictionary https://medical-dictionary.thefreedictionary.com/cefotetan ...
more infohttp://medical-dictionary.thefreedictionary.com/cefotetan

Cefotetan | Profiles RNSCefotetan | Profiles RNS

"Cefotetan" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... This graph shows the total number of publications written about "Cefotetan" by people in this website by year, and whether " ... Below are the most recent publications written about "Cefotetan" by people in Profiles. ...
more infohttps://profiles.umassmed.edu/display/122571

Cefotetan (CAS 69712-56-7) Market Research Report 2018Cefotetan (CAS 69712-56-7) Market Research Report 2018

Market Research Report 2018 aims at providing comprehensive data on cefotetan market globally and regionally (Europe, Asia, ... Cefotetan prices in North America. 6.4. Cefotetan prices in other regions. 7. CEFOTETAN END-USE SECTOR 7.1. Cefotetan market by ... Cefotetan market forecast. 6. CEFOTETAN MARKET PRICES. 6.1. Cefotetan prices in Europe. 6.2. Cefotetan prices in Asia 6.3. ... 2. CEFOTETAN APPLICATIONS. 2.1. Cefotetan application spheres, downstream products. 3. CEFOTETAN MANUFACTURING METHODS. 4. ...
more infohttps://marketpublishers.com/report/industry/chemicals_petrochemicals/cefotetan_69712-56-7_market_research_report.html

CefotetanCefotetan

... is a type of injection given to treat or prevent certain bacterial infections. This page from the eMedTV site takes a ... Click Cefotetan Dosage for more information.). Drug Interactions. Cefotetan may react with a number of other medicines (see ... What Should I Do If I Miss a Dose of Cefotetan?. If you miss an appointment to receive a Cefotetan dose, contact your ... Dosing Information for Cefotetan. The dose of cefotetan your healthcare provider recommends will vary, depending on various ...
more infohttp://bacteria.emedtv.com/cefotetan/cefotetan-p3.html

Cefotetan (By injection)Cefotetan (By injection)

Cefotetan (sef-oh-TEE-tan) Treats infections caused by bacteria. This medicine is a cephalosporin antibiotic. Brand Name(s): ... Cefotetan (By injection) Cefotetan (By injection). Drug Information Cefotetan (sef-oh-TEE-tan). Treats infections caused by ... Results for by, cefotan, cefotetan, cefotetan (by injection), doctor. * Experience to Share: Facebook Page Helps Families Hit ... Do not receive it if you had an allergic reaction to cefotetan or any other cephalosporin antibiotic.. How to Use This Medicine ...
more infohttps://www.baptistjax.com/health-library/drugnotes/cefotetan-by-injection

Drug Interactions With CefotetanDrug Interactions With Cefotetan

... cefotetan can interact with warfarin, probenecid, and other drugs. This article explains how you can reduce your risk of ... An Overview of Cefotetan Interactions. Cefotetan (Cefotan®) may interact with a few other products. Some of the drugs that can ... Drug Interactions With Cefotetan. Before you receive cefotetan, your healthcare provider will need to be aware of your alcohol ... Interested in a Discount on Cefotetan?. Our free DiscountRx savings card can help you and your family save money on your ...
more infohttp://bacteria.emedtv.com/cefotetan/drug-interactions-with-cefotetan.html

cefotetan 2 gram/50 mL in dextrose (iso-osmotic) intravenous piggyback  | Kaiser Permanentecefotetan 2 gram/50 mL in dextrose (iso-osmotic) intravenous piggyback | Kaiser Permanente

Cefotetan is an antibiotic used to treat a wide variety of bacterial infections. It may also be used before and during certain ... Cefotetan is an antibiotic used to treat a wide variety of bacterial infections. It may also be used before and during certain ... Before using cefotetan, tell your doctor or pharmacist if you are allergic to it; or to other cephalosporins; or to penicillins ... Cefotetan may cause live bacterial vaccines (such as typhoid vaccine) to not work as well. Do not have any immunizations/ ...
more infohttps://healthy.kaiserpermanente.org/georgia/health-wellness/drug-encyclopedia/drug.cefotetan-2-gram-50-ml-in-dextrose-iso-osmotic-intravenous-piggyback.553468

CefotetanCefotetan

Click to view prices and info for Cefotetan on TOKU-E.com ... Buy and view Cefotetan, for anti-anaerobe applications, 69712- ... Cefotetan Disodium (C117). Cefotetan is sparingly soluble in water (0.51 mg/mL) and cefotetan disodium is slightly more soluble ... Cefotetan is a cephamycin antibiotic grouped with the second-generation cephalosporins. TOKU-E offers two forms of cefotetan: * ... Cefotetan is a broad-spectrum antibiotic targeting a wide variety of gram-positive and gram-negative bacteria. Like many ...
more infohttps://www.toku-e.com/product/cefotetan/

Radiation recall dermatitis with cefotetan: A case study<...Radiation recall dermatitis with cefotetan: A case study<...

Ayoola, A., & Young, J. L. (2006). Radiation recall dermatitis with cefotetan: A case study. Oncologist, 11(10), 1118-1120. ... Ayoola, A & Young, JL 2006, Radiation recall dermatitis with cefotetan: A case study, Oncologist, vol. 11, no. 10, pp. 1118- ... Four months later, she was admitted to the hospital for acute cholecystitis and was placed on cefotetan. She developed a tender ... Four months later, she was admitted to the hospital for acute cholecystitis and was placed on cefotetan. She developed a tender ...
more infohttps://pennstate.pure.elsevier.com/en/publications/radiation-recall-dermatitis-with-cefotetan-a-case-study

cefoTEtan | Daviss Drug GuidecefoTEtan | Davis's Drug Guide

cefoTEtan answers are found in the Daviss Drug Guide powered by Unbound Medicine. Available for iPhone, iPad, Android, and Web ... www.drugguide.com/ddo/view/Davis-Drug-Guide/109022/all/cefoTEtan. Quiring C, Sanoski CA, Vallerand AH. CefoTEtan. Daviss Drug ... cefoTEtan is a topic covered in the Daviss Drug Guide. To view the entire topic, please sign in or purchase a subscription. ... TY - ELEC T1 - cefoTEtan ID - 109022 A1 - Quiring,Courtney, AU - Sanoski,Cynthia A, AU - Vallerand,April Hazard, BT - Daviss ...
more infohttps://www.drugguide.com/ddo/view/Davis-Drug-Guide/109022/all/cefoTEtan

Cefotetan Safe While Breastfeeding? :: NIH LactMedCefotetan Safe While Breastfeeding? :: NIH LactMed

Cefotetan is acceptable to use during breastfeeding.. Drug Levels:. Maternal Levels.. After a single 1 gram dose of cefotetan ... After a single 1 gram dose of cefotetan in 2 women, average cefotetan concentrations of 0.1 and 0.2 mg/L occurred at 2 and 4 ... Five women were given 1 gram of cefotetan every 12 hours intramuscularly for 2 days. Milk cefotetan levels were undetectable 1 ... A moderate amount of information indicates that maternal doses of cefotetan up to 2 grams daily produce low levels in milk that ...
more infohttp://anikamd.com/breastfeeding/cefotetan.htm

Cefotetan - For All Medical Treatment Options Explained, Visit CureCrowdCefotetan - For All Medical Treatment Options Explained, Visit CureCrowd

Cefotetan. Also Known As: Cefotetan, Apatef, Cefotan. Cefotetan is an injectable antibiotic of the cephamycin type for ... Cefotetan was developed by Yamanouchi. It is marketed outside Japan by AstraZeneca with the brand names Apatef and Cefotan. ... Complete a survey on Cefotetan to help the CureCrowd community. If you have tried to treat this ailment, please complete the ...
more infohttps://www.curecrowd.com/treatments/cefotetan

Neck Trauma Medication: AntibioticsNeck Trauma Medication: Antibiotics

Cefotetan (Cefotan). *View full drug information. Second-generation cephalosporin indicated for infections caused by ...
more infohttps://emedicine.medscape.com/article/827223-medication

Second Generation Anti-anaerobe CephalosporinsSecond Generation Anti-anaerobe Cephalosporins

Cefotetan [Chemical/Ingredient], CEFOTETAN, cefoTEtan, cefotetan, Cefotetan (substance), Cefotetan product (product), Cefotetan ... Ontology: Cefotetan. (C0007555) Definition (NCI) A semi-synthetic, broad-spectrum, beta-lactamase-resistant, second-generation ... Cefotetan, 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl ... Cefotetan disodium is more active against gram-negative organisms and less active against gram-positive organisms compared to ...
more infohttps://fpnotebook.com/ID/Pharm/ScndGnrtnAntAnrbCphlsprns.htm
  • If cefotetan or alike drugs caused low red blood cell counts before. (drugs.com)
  • You must check to make sure that it is safe for you to take cefotetan with all of your drugs and health problems. (drugs.com)
  • The chance of getting hemolytic anemia may be higher with cefotetan than with other drugs like this one. (drugs.com)
  • The following sections explain in detail the potentially negative reactions that can occur when cefotetan is combined with any of the drugs listed above. (emedtv.com)
  • The bactericidal action of cefotetan results from inhibition of cell wall synthesis by binding and inhibiting the bacterial penicillin binding proteins which help in the cell wall biosynthesis. (drugbank.ca)
  • 1. Cho N, Fukunaga K, Kuni K. Fundamental and clinical studies on cefotetan (YM09330) in the field of obstetrics and gynecology. (anikamd.com)
  • A moderate amount of information indicates that maternal doses of cefotetan up to 2 grams daily produce low levels in milk that are not expected to cause adverse effects in breastfed infants. (anikamd.com)
  • Cefotetan has a broad spectrum of activity and has been used to treat bacterial infections of the bone, skin, urinary tract, and lower respiratory tract. (wikipedia.org)
  • Cefotetan is commonly used in clinical in vitro microbiological antimicrobial susceptibility tests (panels, discs, and MIC strips) against aerobic and anaerobic gram positive and gram negative microbial isolates. (toku-e.com)
  • Probenecid ↓ excretion and ↑ blood levels.If alcohol is ingested within 48-72 hr of cefotetan, a disulfiram-like reaction may occur.May potentiate the effects of anticoagulants and ↑ the risk of bleeding.Concurrent use of aminoglycosides may ↑ the risk of nephrotoxicity. (thefreedictionary.com)
  • What conditions does Cefotetan Vial treat? (webmd.com)
  • Cefotetan will not treat a viral infection such as the flu or a common cold . (emedicinehealth.com)
  • 2019. https://www.drugguide.com/ddo/view/Davis-Drug-Guide/109022/all/cefoTEtan. (drugguide.com)
  • however, small amounts (less than 7%) of cefotetan in plasma and urine may be converted to its tautomer, which has antimicrobial activity similar to the parent drug. (drugbank.ca)
  • Storage recommendations after reconstitution may vary, depending on what type of liquid is used and the particular cefotetan product being used. (emedtv.com)
  • Cefotetan" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)