A third-generation cephalosporin antibiotic that is stable to hydrolysis by beta-lactamases.
Semisynthetic broad-spectrum cephalosporin.
A broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears.
Semisynthetic, broad-spectrum antibiotic derivative of CEPHALEXIN.
A species of gram-negative, aerobic bacteria primarily found in purulent venereal discharges. It is the causative agent of GONORRHEA.
Acute infectious disease characterized by primary invasion of the urogenital tract. The etiologic agent, NEISSERIA GONORRHOEAE, was isolated by Neisser in 1879.
A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe and effective in aged patients and in patients with hematologic disorders.
Substances that reduce the growth or reproduction of BACTERIA.
Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).
An inorganic compound that occurs in nature as the mineral brucite. It acts as an antacid with cathartic effects.

Interpretation of middle ear fluid concentrations of antibiotics: comparison between ceftibuten, cefixime and azithromycin. (1/116)

AIMS: The aim of this study was to determine the potential influence of variables such as the cell content in the fluid, and serum levels, on the concentrations of ceftibuten, cefixime and azithromycin in the middle ear fluid of patients suffering from acute otitis media. METHODS: This randomized, open study compared the penetration of ceftibuten (9 mg kg(-1) 18 patients), cefixime (8 mg kg(-1), 16 patients) and azithromycin (10 mg kg(-1) 16 patients) into the intracellular and extracellular compartments of middle ear fluid of 50 paediatric patients (aged 8-14 years) with acute otitis media. Middle ear fluid was extracted by tympanocentesis 4, 12 and 24 h after dosing and divided into two fractions: with cells (as collected) (C+) and cell-free (C-). Antibiotics were assayed in C+ and C- samples by h.p.l.c. RESULTS: Ceftibuten achieved greater penetration into middle ear fluid than cefixime and azithromycin. Higher concentrations of ceftibuten (CTB) and cefixime (CFX) were found in the C- fraction (CTB: 4h 13.3+/-1.86; 12h 4.7+/-1.18; 24h 0.5+/-0.2. CFX: 4h 3.2+/-1.4; 12h 1.5+/-0.5; 24h>(0.1 mgl(-1)) than in the C+ fraction (CTB:4 h 8.4+/-4.3; 12 h 2.88+/-1.19; 24 h 0.3+/-0.27. CFX: 4 h 1.2+/-0.6; 12 h 0.8+/-0.2; 24 h>0.1 mg l(-1)) at the each time point, while the opposite was true for azithromycin (C-: 4 h 0.11+/-0.04; 12 h 0.12+/-0.08; 24 h 0.23+/-0.12. C+: 4 h 0.38+/-0.24; 12 h 0.9+/-0.03; 24 h 1.05+/-0.3 mg l(-1)). CONCLUSIONS: This study demonstrates that the penetration of antibiotics into the middle ear fluid is influenced by its serum concentrations as well as by the cell content in the fluid. Ceftibuten achieved higher middle ear fluid concentrations than cefixime in C+ and C- fractions at all time points. Both ceftibuten and cefixime concentrations are negatively influenced by the cell content in the fluid. In contrast the concentration of azithromycin to the middle ear fluid is positively influenced by the cell content in the fluid.  (+info)

Intestinal absorption of cefixime in rats. (2/116)

AIM: To study the intestinal absorption characters of cefixime (Cef) and the factors affecting Cef absorption. METHODS: A rat intestine loop in situ technique was used to investigate the disappearance rate of Cef from the intestine. Cef concentration in the flux was measured by the reversed phase HPLC. RESULTS: Cef was mainly absorbed from the upper part of the intestine. Its disappearance rate was apparently pH-dependent [(5.8 +/- 0.6) nmol.h-1/(g wet tissue) at pH 7.4, (8.9 +/- 1.4) nmol.h-1/(g wet tissue) at pH 5.0, P < 0.05)]. The uptake rate of Cef was curvilinear at 0.01-0.5 mmol.L-1. The values of apparent Kt, Jmax, and Kd were 0.114 mmol, 78.41 nmol.h-1/(g wet tissue), and 43.70 nmol.h-1.mmol-1/(g wet tissue), respectively. Sodium edetate markedly promoted the disappearance rate of Cef from the intestine. CONCLUSION: Cef was transported partly via carrier-mediated transport system and partly via the paracellular transport system.  (+info)

Sequential antimicrobial therapy: treatment of severe lower respiratory tract infections in children. (3/116)

Although there have been a number of studies in adults, to date there has been little research into sequential antimicrobial therapy (SAT) in paediatric populations. The present study evaluates the impact of a SAT protocol for the treatment of severe lower respiratory tract infection in paediatric patients. The study involved 89 paediatric patients (44 control and 45 SAT). The SAT patients had a shorter length of hospital stay (4.0 versus 8.3 days), shorter duration of inpatient antimicrobial therapy (4.0 versus 7.9 days) with the period of iv therapy being reduced from a mean of 5.6 to 1.7 days. The total healthcare costs were reduced by 52%. The resolution of severe lower respiratory tract infection with a short course of iv antimicrobials, followed by conversion to oral therapy yielded clinical outcomes comparable to those achieved using longer term iv therapy. SAT proved to be an important cost-minimizing tool for realizing substantial healthcare costs savings.  (+info)

Susceptibilities of Yersinia pestis strains to 12 antimicrobial agents. (4/116)

Ninety-two strains of Yersinia pestis recovered over a 21-year period were evaluated for susceptibility to traditional and newer antimicrobial agents. In vitro resistance was noted only against rifampin and imipenem (approximately 20% of strains). The most active compounds (MIC at which 90% of the isolates tested are inhibited) against Y. pestis were cefixime, ceftriaxone, trimethoprim-sulfamethoxazole, and trovafloxacin.  (+info)

Modification of sorbitol MacConkey medium containing cefixime and tellurite for isolation of Escherichia coli O157:H7 from radish sprouts. (5/116)

A modified version of sorbitol MacConkey medium containing cefixime and tellurite (CT-SMAC medium) was produced by adding salicin and 4-methylumbelliferyl-beta-D-galactopyranoside to CT-SMAC medium; this medium was designated CT-SSMAC medium and was used to isolate Escherichia coli O157:H7 from radish sprouts. Of 101 non-E. coli bacteria isolated from radish sprouts that produced colorless colonies similar to colonies of E. coli O157:H7 grown on CT-SMAC medium, 92 (91%) formed colonies that were red to pink or were beta-galactosidase negative and colorless on CT-SSMAC medium. On the other hand, colonies of E. coli O157:H7 strains were colorless and beta-galactosidase positive on CT-SSMAC medium. Our results suggest that CT-SSMAC medium is more selective than CT-SMAC medium for isolating E. coli O157:H7.  (+info)

Cost-effectiveness of management strategies for acute urethritis in the developing world. (6/116)

OBJECTIVE: To recommend a cost-effective approach for the management of acute male urethritis in the developing world, based on the findings of a theoretical study. METHODS: A model was developed to assess the cost-effectiveness of three urethritis management strategies in a theoretical cohort of 1000 men with urethral syndrome. (1) All patients were treated with cefixime and doxycycline for gonococcal urethritis (GU) and nongonococcal urethritis (NGU), respectively, as recommended by WHO. (2) All patients were treated with doxycycline for NGU; treatment with cefixime was based on the result of direct microscopy of a urethral smear. (3) All patients were treated with cotrimoxazole or kanamycin for GU and doxycycline for NGU. Cefixime was kept for patients not responding to the first GU treatment. Strategy costs included consultations, laboratory diagnosis (where applicable) and drugs. The outcome was the rate of patients cured of urethritis. Cost-effectiveness was measured in terms of cost per cured urethritis. RESULTS: Strategy costs in our model depended largely on drug costs. The first strategy was confirmed as the most effective but also the most expensive approach. Cefixime should cost no more than US$ 1.5 for the strategy to be the most cost-effective. The second strategy saved money and drugs but proved a valuable alternative only when laboratory performance was optimal. The third strategy with cotrimoxazole was the least expensive but a low follow-up visit rate, poor treatment compliance or lower drug efficacy limited effectiveness. Maximizing compliance by replacing cotrimoxazole with single-dose kanamycin had the single greatest impact on the effectiveness of the third strategy. CONCLUSION: Our model suggested that a cost-effective approach would be to treat gonorrhoea with a single-dose antibiotic selected from locally available products that cost no more than US$ 1.5.  (+info)

Oral cefixime is similar to continued intravenous antibiotics in the empirical treatment of febrile neutropenic children with cancer. (7/116)

Empiric oral antibiotic therapy for febrile neutropenic cancer patients has been suggested as a means to decrease hospitalization, but the safety of this approach has not been adequately studied in children. We compared continued iv antibiotic therapy with switching treatment to orally administered cefixime in a group of selected febrile neutropenic children for whom blood cultures were sterile after 48 h of incubation. Two hundred episodes of febrile neutropenia were studied (156 patients), and 100 episodes were randomized to receive each treatment. Failure to respond to therapy was defined by documented or suspected bacterial infection, recurrent fever, or discontinuation of assigned therapy for any reason before neutropenia resolved. Rates of treatment failure were similar in the oral cefixime group (28%) and in the iv antibiotic group (27%; P=1.0). Results support the safety of oral cefixime therapy for low-risk febrile neutropenic children, a therapeutic approach that would facilitate earlier outpatient management and decrease the costs of treatment.  (+info)

A randomized trial of ciprofloxacin versus cefixime for treatment of gonorrhea after rapid emergence of gonococcal ciprofloxacin resistance in The Philippines. (8/116)

From 1994 through 1996-1997, high-level ciprofloxacin resistance (minimum inhibitory concentration [MIC], > or = 4.0 microg/mL) increased from 9% to 49% of gonococcal isolates recovered from consecutive female sex workers in Cebu and Manila, The Philippines (P < .01). During 1996-1997, 105 female sex workers with gonorrhea were prospectively randomized to receive treatment with oral ciprofloxacin, 500 mg, or cefixime, 400 mg, and followed for test of cure. Neisseria gonorrhoeae was reisolated within 28 days after treatment from 1 (3.8%) of 26 women given cefixime versus 24 (32.3%) of 72 women given ciprofloxacin (P < .01). Treatment failure (reisolation of pretreatment auxotype/serovar) occurred in 14 (46.7%) of 30 women infected with strains with MICs of ciprofloxacin > or = 4.0 microg/mL versus 1 (3.6%) of 28 infected by strains with MICs < 4.0 microg/mL (P < .01). High-level, clinically significant gonococcal resistance to ciprofloxacin has rapidly emerged in The Philippines, and spread of fluoroquinolone resistance through commercial sex poses a threat to control of gonorrhea and prevention of human immunodeficiency virus infection and the acquired immunodeficiency syndrome.  (+info)

Cefixime is a third-generation cephalosporin antibiotic, which is used to treat various bacterial infections. It works by inhibiting the synthesis of the bacterial cell wall. Cefixime is available as an oral suspension or tablet and is commonly prescribed for respiratory tract infections, urinary tract infections, ear infections, and skin infections.

The medical definition of Cefixime can be stated as follows:

Cefixime: A semisynthetic antibiotic derived from cephalosporin, which is used to treat a variety of bacterial infections. It has a broad spectrum of activity against both Gram-positive and Gram-negative bacteria, including beta-lactamase producing strains. Cefixime is administered orally and is often prescribed for respiratory tract infections, urinary tract infections, ear infections, and skin infections. It has a long half-life and high oral bioavailability, making it a convenient option for outpatient treatment.

Common side effects of Cefixime include diarrhea, nausea, vomiting, abdominal pain, and headache. Serious side effects are rare but may include anaphylaxis, Stevens-Johnson syndrome, and toxic epidermal necrolysis. Caution should be exercised when prescribing Cefixime to patients with a history of allergic reactions to cephalosporins or penicillins.

Cefotaxime is a third-generation cephalosporin antibiotic, which is used to treat a variety of bacterial infections. It works by inhibiting the synthesis of the bacterial cell wall. Cefotaxime has a broad spectrum of activity and is effective against many Gram-positive and Gram-negative bacteria, including some that are resistant to other antibiotics.

Cefotaxime is often used to treat serious infections such as pneumonia, meningitis, and sepsis. It may also be used to prevent infections during surgery or in people with weakened immune systems. The drug is administered intravenously or intramuscularly, and its dosage depends on the type and severity of the infection being treated.

Like all antibiotics, cefotaxime can cause side effects, including diarrhea, nausea, vomiting, and rash. In rare cases, it may cause serious allergic reactions or damage to the kidneys or liver. It is important to follow the prescribing physician's instructions carefully when taking this medication.

Ceftriaxone is a third-generation cephalosporin antibiotic, which is used to treat a wide range of bacterial infections. It works by inhibiting the synthesis of the bacterial cell wall. Ceftriaxone has a broad spectrum of activity and is effective against many gram-positive and gram-negative bacteria, including some that are resistant to other antibiotics.

Ceftriaxone is available in injectable form and is commonly used to treat serious infections such as meningitis, pneumonia, and sepsis. It is also used to prevent infections after surgery or trauma. The drug is generally well-tolerated, but it can cause side effects such as diarrhea, nausea, vomiting, and rash. In rare cases, it may cause serious side effects such as anaphylaxis, kidney damage, and seizures.

It's important to note that Ceftriaxone should be used only under the supervision of a healthcare professional, and that it is not recommended for use in individuals with a history of allergic reactions to cephalosporins or penicillins. Additionally, as with all antibiotics, it should be taken as directed and for the full duration of the prescribed course of treatment, even if symptoms improve before the treatment is finished.

Cefaclor is a type of antibiotic known as a second-generation cephalosporin. It works by interfering with the bacteria's ability to form a cell wall, which is necessary for its survival. Without a functional cell wall, the bacteria eventually die. Cefaclor is effective against a wide range of gram-positive and gram-negative bacteria, making it a broad-spectrum antibiotic.

Cefaclor is used to treat various types of bacterial infections, including respiratory tract infections (such as bronchitis and pneumonia), ear infections, skin infections, and urinary tract infections. It is available in both oral and intravenous forms.

Like all antibiotics, cefaclor should be used only to treat bacterial infections, as it is not effective against viral infections such as the common cold or flu. Overuse of antibiotics can lead to the development of antibiotic-resistant bacteria, which can make future infections more difficult to treat. It is important to take cefaclor exactly as directed by a healthcare professional and to complete the full course of treatment, even if symptoms improve before all of the medication has been taken.

Neisseria gonorrhoeae is a species of gram-negative, aerobic diplococcus that is the etiologic agent of gonorrhea, a sexually transmitted infection. It is commonly found in the mucous membranes of the reproductive tract, including the cervix, urethra, and rectum, as well as the throat and eyes. The bacterium can cause a range of symptoms, including discharge, burning during urination, and, in women, abnormal menstrual bleeding. If left untreated, it can lead to more serious complications, such as pelvic inflammatory disease and infertility. It is important to note that N. gonorrhoeae has developed resistance to many antibiotics over time, making treatment more challenging. A culture or nucleic acid amplification test (NAAT) is used for the diagnosis of this infection.

Gonorrhea is a sexually transmitted infection (STI) caused by the bacterium Neisseria gonorrhoeae, also known as "gono" bacteria. It can infect various parts of the body including the genitals, rectum, and throat. The bacteria are typically transmitted through sexual contact with an infected person.

Symptoms may vary but often include abnormal discharge from the genitals or rectum, painful or burning sensations during urination, and in women, vaginal bleeding between periods. However, many people with gonorrhea do not develop symptoms, making it essential to get tested regularly if you are sexually active with multiple partners or have unprotected sex.

If left untreated, gonorrhea can lead to severe complications such as pelvic inflammatory disease (PID) in women and epididymitis in men, which may result in infertility. In rare cases, it can spread to the bloodstream and cause life-threatening conditions like sepsis.

Gonorrhea is curable with appropriate antibiotic treatment; however, drug-resistant strains of the bacteria have emerged, making accurate diagnosis and effective treatment increasingly challenging. Prevention methods include using condoms during sexual activity and practicing safe sex habits.

Ceftizoxime is a type of antibiotic known as a third-generation cephalosporin. It works by interfering with the bacteria's ability to form a cell wall, which is necessary for its survival. Ceftizoxime is effective against a wide range of gram-positive and gram-negative bacteria, including many that are resistant to other antibiotics.

It is commonly used to treat various types of infections, such as pneumonia, urinary tract infections, skin infections, and intra-abdominal infections. Ceftizoxime is available in both intravenous (IV) and oral forms, although the IV form is more commonly used in clinical practice.

Like all antibiotics, ceftizoxime should be used only to treat bacterial infections, as it has no effect on viral infections. Overuse or misuse of antibiotics can lead to the development of antibiotic resistance, which makes it more difficult to treat infections in the future.

It is important to note that ceftizoxime should only be used under the supervision of a healthcare provider, who will determine the appropriate dosage and duration of treatment based on the patient's individual needs and medical history.

Anti-bacterial agents, also known as antibiotics, are a type of medication used to treat infections caused by bacteria. These agents work by either killing the bacteria or inhibiting their growth and reproduction. There are several different classes of anti-bacterial agents, including penicillins, cephalosporins, fluoroquinolones, macrolides, and tetracyclines, among others. Each class of antibiotic has a specific mechanism of action and is used to treat certain types of bacterial infections. It's important to note that anti-bacterial agents are not effective against viral infections, such as the common cold or flu. Misuse and overuse of antibiotics can lead to antibiotic resistance, which is a significant global health concern.

Microbial sensitivity tests, also known as antibiotic susceptibility tests (ASTs) or bacterial susceptibility tests, are laboratory procedures used to determine the effectiveness of various antimicrobial agents against specific microorganisms isolated from a patient's infection. These tests help healthcare providers identify which antibiotics will be most effective in treating an infection and which ones should be avoided due to resistance. The results of these tests can guide appropriate antibiotic therapy, minimize the potential for antibiotic resistance, improve clinical outcomes, and reduce unnecessary side effects or toxicity from ineffective antimicrobials.

There are several methods for performing microbial sensitivity tests, including:

1. Disk diffusion method (Kirby-Bauer test): A standardized paper disk containing a predetermined amount of an antibiotic is placed on an agar plate that has been inoculated with the isolated microorganism. After incubation, the zone of inhibition around the disk is measured to determine the susceptibility or resistance of the organism to that particular antibiotic.
2. Broth dilution method: A series of tubes or wells containing decreasing concentrations of an antimicrobial agent are inoculated with a standardized microbial suspension. After incubation, the minimum inhibitory concentration (MIC) is determined by observing the lowest concentration of the antibiotic that prevents visible growth of the organism.
3. Automated systems: These use sophisticated technology to perform both disk diffusion and broth dilution methods automatically, providing rapid and accurate results for a wide range of microorganisms and antimicrobial agents.

The interpretation of microbial sensitivity test results should be done cautiously, considering factors such as the site of infection, pharmacokinetics and pharmacodynamics of the antibiotic, potential toxicity, and local resistance patterns. Regular monitoring of susceptibility patterns and ongoing antimicrobial stewardship programs are essential to ensure optimal use of these tests and to minimize the development of antibiotic resistance.

Magnesium hydroxide is an inorganic compound with the chemical formula Mg(OH)2. It is a white solid that is amphoteric, meaning it can react as both an acid and a base. Magnesium hydroxide is commonly used as an over-the-counter antacid to neutralize stomach acid and relieve symptoms of heartburn, acid indigestion, and upset stomach. It works by increasing the pH of the stomach, which can help to reduce the production of stomach acid.

Magnesium hydroxide is also used as a laxative to relieve constipation, as it has a softening effect on stools and stimulates bowel movements. In addition, magnesium hydroxide is sometimes used in medical procedures to neutralize or wash away stomach acid, for example during endoscopies or the treatment of poisoning.

It's important to note that while magnesium hydroxide is generally considered safe when used as directed, it can cause side effects such as diarrhea, nausea, and abdominal cramps. In addition, people with kidney disease or severe heart or lung conditions should use magnesium hydroxide with caution, as it can worsen these conditions in some cases.

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Cefixime is a suitable oral alternative. Properly treated, typhoid fever is not fatal in most cases. Antibiotics such as ... Cao XT, Kneen R, Nguyen TA, Truong DL, White NJ, Parry CM (March 1999). "A comparative study of ofloxacin and cefixime for ... Bhutta ZA, Khan IA, Molla AM (November 1994). "Therapy of multidrug-resistant typhoid fever with oral cefixime vs. intravenous ...
Ceftriaxone and cefixime are third generation cephalosporins and are often used as treatments for N. gonorrhoeae infections. ... These include: cefixime (an oral cephalosporin), ceftriaxone (an injectable cephalosporin), azithromycin, aminoglycosides, and ... Unemo, Golparian, Nicholas, Ohnishi, Gallay, Sednaoui (2011) High-Level Cefixime- and Ceftriaxone-Resistant Neisseria ...
Cefixime: an oral option for the treatment of multidrug-resistant enteric fever in children. Retrieved, US National Library of ... Cefixime: an oral option for the treatment of multidrug-resistant enteric fever in children. Detection and management of ...
The treatment of choice is often azithromycin and cefixime to cover both gonorrhoeae and chlamydia. Fluoroquinolones are no ...
Cefixime 400 mg oral single dose can be used as an alternative if ceftriaxone is not available. Non-gonococcal urethritis ( ...
This is for example done with cefixime and cefdinir by putting a vinyl group in the C-3 position. The fourth generation ...
The sample is cultured on sorbitol-MacConkey (SMAC) agar, or the variant cefixime potassium tellurite sorbitol-MacConkey agar ( ...
... doxycycline was considered a first-line treatment for chlamydia and non-gonococcal urethritis and with cefixime for ...
... cefixime (antibiotic), barbiturates (sedatives), lamotrigine, phenytoin (e.g., Dilantin) (anticonvulsants) and trimethoprim. ...
... cefixime (INN) Cefizox cefluprenam (INN) Cefmax cefmenoxime (INN) cefmepidium chloride (INN) cefmetazole (INN) cefminox (INN) ...
Canada Cefixime, by the trade name CFIX This disambiguation page lists articles associated with the title CFIX. If an internal ...
Resistance to cefixime has reached a level such that it is no longer recommended as a first-line agent in the United States, ...
Children with acute pyelonephritis can be treated effectively with oral antibiotics (cefixime, ceftibuten and amoxicillin/ ...
Trimethoprim Azithromycin Cefixime Cefotaxime Ceftriaxone Cefuroxime Ciprofloxacin Clarithromycin Piperacillin/tazobactam ( ...
... cefprozil Cefaclor Cefamandole Cefuroxime Cefotetan Cefoxitin Cefixime Cefotaxime Cefpodoxime Ceftazidime Ceftriaxone Cefdinir ...
... cefixime MeSH D02.065.589.099.249.190.190.125 - cefmenoxime MeSH D02.065.589.099.249.190.190.135 - cefotiam MeSH D02.065. ...
Trimethoprim Azithromycin Cefixime Cefotaxime Ceftriaxone Cefuroxime Ciprofloxacin Clarithromycin Piperacillin/tazobactam ( ...
Cefixime), a paediatric antibiotic, is Lupin's top-selling product here. Other products in Lupin's branded portfolio include ...
Cefixime) Tavanic (Levofloxacin) Vaccines: Bacterial diseases: ActHIB (Hib vaccine) Adacel (DPT vaccine) Daptacel (DPT vaccine ...
... oral cefixime or cefuroxime and injectable cefotaxime, ceftazidime, and ceftriaxone can be used with caution, but the use of ...
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J01RA13 Norfloxacin and tinidazole J01RA14 Norfloxacin and metronidazole J01RA15 Cefixime and ornidazole J01RA16 Cefixime and ... Ceftazidime J01DD03 Cefsulodin J01DD04 Ceftriaxone J01DD05 Cefmenoxime J01DD06 Latamoxef J01DD07 Ceftizoxime J01DD08 Cefixime ...
... may refer to: Encef, a trade name in India for cefixime Encef, a trade name in India for ceftriaxone Encef, a trade name ...
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Cefixime: learn about side effects, dosage, special precautions, and more on MedlinePlus ... Continue to take cefixime even if you feel better. If you stop taking cefixime too soon or skip doses, your infection may not ... Before taking cefixime,. *tell your doctor and pharmacist if you are allergic to cefixime; other cephalosporin antibiotic such ... Cefixime tablets come with a line down the middle of the tablet. If your doctor tells you to take half a tablet, break it ...
North American strains of Neisseria gonorrhoeae have been found to be resistant to cefixime, the only available oral antibiotic ... Growing global resistance by Neisseria gonorrhoeae to cefixime, the last oral antibiotic used against it, has been documented ... "This study presents the first series of clinical failures of gonorrhea associated with the use of cefixime in North America, ... The CDC last year updated its gonorrhea treatment recommendations and no longer considers cefixime part of a first-line regimen ...
Lupin has been manufacturing and marketing cefixime oral suspension (100 mg/5 mL) since February 2004 and cefixime oral ... discontinued manufacturing cefixime tablets in the United States (2). Beginning in April 2008, cefixime (Suprax®) 400 mg ... of cefixime 400 mg (1). Availability of cefixime had been limited since July 2002, when Wyeth Pharmaceuticals (Collegeville, ... Information on obtaining cefixime is available from Lupin by telephone (866-587-4617). Guidance on treatment of N. gonorrhoeae ...
For treating bacterial infection. Brand Name(s): Suprax. Generic Name: Cefixime.
For treating bacterial infection. Brand Name(s): Suprax. Generic Name: Cefixime.
Number of isolates tested for cefixime (Sexually Transmitted Infections). This indicator is available in the following set of ...
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  • isolates with cefixime MICs 0.25 μg/mL or greater increased from 0.2% to 1.4% and isolates with ceftriaxone MICs 0.12 μg/mL or greater increased from 0.1% to 0.3%," the authors write. (medscape.com)
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  • Seven of the 9 isolates had a cefixime MIC of at least 0.12 μg/mL, and the remaining 2 isolates had MICs of less than 0.12 μg/mL," the authors note. (medscape.com)
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  • Cefixime is used for the treatment of bacterial infections in different parts of the body. (thehouseofgoodies.com)
  • Cefixime is used to treat this bacterial infection. (drugcarts.com)
  • The antibacterial effect of cefixime results from inhibition of mucopeptide synthesis in the bacterial cell wall. (healingpharma.net)
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  • The only oral agent recommended currently by CDC for treatment of uncomplicated urogenital or rectal gonorrhea is a single dose of cefixime 400 mg ( 1 ). (cdc.gov)
  • In 2001, treatment failure was reported in a Caucasian man residing in Hawaii who had been given a single 400-mg dose of cefixime for gonorrhea ( 8 ). (cdc.gov)
  • This man was successfully treated with a single 400-mg dose of cefixime. (cdc.gov)
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  • You should begin to feel better during the first few days of treatment with cefixime. (medlineplus.gov)
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  • If you stop taking cefixime too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics. (medlineplus.gov)
  • Cefixime is used to treat many different types of infections caused by bacteria. (foryourx.com)
  • Under this condition, the active usage of the Cefixime Oral Suspension Syrup may help in the prevention of the bacteria by preventing them from spreading and killing their cells. (medlockhealthcare.in)
  • Clavulanic Acid reduces the resistance and enhances the activity of Cefixime against bacteria. (servocarelifesciences.in)
  • Lupin has been manufacturing and marketing cefixime oral suspension (100 mg/5 mL) since February 2004 and cefixime oral suspension (200 mg/5 mL) since April 2007. (cdc.gov)
  • In vivo study was carried out using Pluronic sd in male Wister rats (n=6) and which showed enhanced absorption of Cefixime with AUC 1.9 times greater than of the aqueous plain Cefixime suspension. (omicsonline.org)
  • DAYTON, N.J. - Aurobindo Pharma Ltd. has received the first Abbreviated New Drug Application approval from the Food and Drug Administration for cefixime for oral suspension, USP, 100 mg/5 ml and 200 mg/5 ml. (chaindrugreview.com)
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  • Allergic reaction to Cefixime or any other similar antibiotics such as cefalexin, cefuroxime, and other cephalosporin antibiotics. (healingpharma.net)
  • Urinary tract infections (UTIs) may be treated with various oral antibiotics, most commonly trimethoprim and sulfamethoxazole, amoxicillin, or cefixime. (medscape.com)
  • medical citation needed] Cefixime is contraindicated in patients with known sensitivity or allergies to cephalosporin class of antibiotics. (wikipedia.org)
  • Cefixime is in a class of medications called cephalosporin antibiotics. (medlineplus.gov)
  • Antibiotics such as cefixime will not work for colds, flu, or other viral infections. (medlineplus.gov)
  • Cefixime is in a group of drugs called cephalosporin (SEF a low spor in) antibiotics. (foryourx.com)
  • These antibiotics happen to be very effective in the treatment of gonorrhea, however warning signs of resistance have emerged particularly with cefixime. (tesseracttheatreensemble.com)
  • This recommendation was made to preserve the last highly effective class of antibiotics left to treat gonorrhea (i.e., cephalosporins) for as long as possible after laboratory data suggested that the oral cephalosporin, cefixime, was becoming less effective. (cdc.gov)
  • This study presents the first series of clinical failures of gonorrhea associated with the use of cefixime in North America, identified by the concurrent strategies of routine test-of-cure and culture-based testing for N gonorrhoeae ," the authors write. (medscape.com)
  • The CDC last year updated its gonorrhea treatment recommendations and no longer considers cefixime part of a first-line regimen. (medscape.com)
  • However, treatment failure with this cefixime regimen was observed in our 4 cases of gonorrhea. (cdc.gov)
  • Long-term or repeated use of Cefixime may cause a second infection. (foryourx.com)
  • Cefixime appears to be effective against pharyngeal gonococcal infection, but few patients with pharyngeal infection have been included in studies. (cdc.gov)
  • Despite the MIC decrease (i.e., trend of improved cefixime susceptibility) during 2012-2013, the increase in the number of strains with Cfx-RS in 2014 underscores the potential threat of cephalosporin-resistant N. gonorrhoeae . (cdc.gov)
  • Oral cefixime is now being provided by Lupin Pharmaceuticals, Inc. (Baltimore, Maryland), which received Food and Drug Administration approval in February 2004 to manufacture and market cefixime. (cdc.gov)
  • Until recently, Japanese guidelines recommended oral administration of cefixime, 200 mg twice a day for 3 days to prolong the period of time for which the serum drug concentration remains above the MIC ( 4 ). (cdc.gov)
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  • Important counseling points of Cefixime + Clavulanic Acid Dry Syrup are mentioned above. (servocarelifesciences.in)
  • During the treatment course with Cefixime + Clavulanic Acid Dry Syrup, an individual patient may experience a few adverse reactions. (servocarelifesciences.in)
  • Q. Is the usage of Cefixime & Clavulanic Acid Dry Syrup contraindicated in patients with impaired renal function? (servocarelifesciences.in)
  • A. Cefixime & Clavulanic Acid Dry Syrup should be administered among the patients with impaired renal function with extra care. (servocarelifesciences.in)
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