Semisynthetic, broad-spectrum antibiotic derivative of CEPHALEXIN.
A semisynthetic cephalosporin antibiotic with antimicrobial activity similar to that of CEPHALORIDINE or CEPHALOTHIN, but somewhat less potent. It is effective against both gram-positive and gram-negative organisms.
A group of broad-spectrum antibiotics first isolated from the Mediterranean fungus ACREMONIUM. They contain the beta-lactam moiety thia-azabicyclo-octenecarboxylic acid also called 7-aminocephalosporanic acid.
A semi-synthetic cephalosporin antibiotic.
A third-generation cephalosporin antibiotic that is stable to hydrolysis by beta-lactamases.
Acids, salts, and derivatives of clavulanic acid (C8H9O5N). They consist of those beta-lactam compounds that differ from penicillin in having the sulfur of the thiazolidine ring replaced by an oxygen. They have limited antibacterial action, but block bacterial beta-lactamase irreversibly, so that similar antibiotics are not broken down by the bacterial enzymes and therefore can exert their antibacterial effects.
Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, GONORRHEA, and HAEMOPHILUS.
Small clusters of chemoreceptive and supporting cells located near the ARCH OF THE AORTA; the PULMONARY ARTERIES; and the CORONARY ARTERIES. The aortic bodies sense PH; CARBON DIOXIDE; and OXYGEN concentrations in the BLOOD and participate in the control of RESPIRATION. The aortic bodies should not be confused with the PARA-AORTIC BODIES in the abdomen (which are sometimes also called aortic bodies).
Long-acting, broad-spectrum, water-soluble, CEPHALEXIN derivative.
A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe and effective in aged patients and in patients with hematologic disorders.
A species of HAEMOPHILUS found on the mucous membranes of humans and a variety of animals. The species is further divided into biotypes I through VIII.
Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).
A broad-spectrum semisynthetic antibiotic similar to AMPICILLIN except that its resistance to gastric acid permits higher serum levels with oral administration.
Clavulanic acid and its salts and esters. The acid is a suicide inhibitor of bacterial beta-lactamase enzymes from Streptomyces clavuligerus. Administered alone, it has only weak antibacterial activity against most organisms, but given in combination with other beta-lactam antibiotics it prevents antibiotic inactivation by microbial lactamase.
A cephalosporin antibiotic.
Substances that reduce the growth or reproduction of BACTERIA.
Semisynthetic wide-spectrum cephalosporin with prolonged action, probably due to beta-lactamase resistance. It is used also as the nafate.
Gram-negative aerobic cocci of low virulence that colonize the nasopharynx and occasionally cause MENINGITIS; BACTEREMIA; EMPYEMA; PERICARDITIS; and PNEUMONIA.
Semisynthetic broad-spectrum cephalosporin.
A mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus. (From Martindale, The Extra Pharmacopoeia, 30th ed, p744)
A fixed-ratio combination of amoxicillin trihydrate and potassium clavulanate.
Behaviors associated with the ingesting of alcoholic beverages, including social drinking.
Infections by bacteria, general or unspecified.
Those persons legally qualified by education and training to engage in the practice of pharmacy.
Voluntary cooperation of the patient in taking drugs or medicine as prescribed. This includes timing, dosage, and frequency.
Time schedule for administration of a drug in order to achieve optimum effectiveness and convenience.
Errors in prescribing, dispensing, or administering medication with the result that the patient fails to receive the correct drug or the indicated proper drug dosage.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
The L-isomer of Ofloxacin.
A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
Patient involvement in the decision-making process in matters pertaining to health.
A subcategory of CHRONIC OBSTRUCTIVE PULMONARY DISEASE. The disease is characterized by hypersecretion of mucus accompanied by a chronic (more than 3 months in 2 consecutive years) productive cough. Infectious agents are a major cause of chronic bronchitis.
Inflammation of the large airways in the lung including any part of the BRONCHI, from the PRIMARY BRONCHI to the TERTIARY BRONCHI.
The Balanced Budget Act (BBA) of 1997 establishes a Medicare+Choice program under part C of Title XVIII, Section 4001, of the Social Security Act. Under this program, an eligible individual may elect to receive Medicare benefits through enrollment in a Medicare+Choice plan. Beneficiaries may choose to use private pay options, establish medical savings accounts, use managed care plans, or join provider-sponsored plans.
Facilities having programs intended to promote and maintain a state of physical well-being for optimal performance and health.
Organizations which assume the financial responsibility for the risks of policyholders.
Federal program, created by Public Law 89-97, Title XVIII-Health Insurance for the Aged, a 1965 amendment to the Social Security Act, that provides health insurance benefits to persons over the age of 65 and others eligible for Social Security benefits. It consists of two separate but coordinated programs: hospital insurance (MEDICARE PART A) and supplementary medical insurance (MEDICARE PART B). (Hospital Administration Terminology, AHA, 2d ed and A Discursive Dictionary of Health Care, US House of Representatives, 1976)
The different methods of scheduling patient visits, appointment systems, individual or group appointments, waiting times, waiting lists for hospitals, walk-in clinics, etc.
A stand-alone drug plan offered by insurers and other private companies to beneficiaries that receive their Medicare Part A and/or B benefits through the Original Medicare Plan. It includes Medicare Private Fee-for-Service Plans that do not offer prescription drug coverage and Medicare Cost Plans offering Medicare prescription drug coverage. The plan was enacted as the Medicare Prescription Drug, Improvement and Modernization Act of 2003 with coverage beginning January 1, 2006.

Structure-function studies of Ser-289 in the class C beta-lactamase from Enterobacter cloacae P99. (1/96)

Site-directed mutagenesis of Ser-289 of the class C beta-lactamase from Enterobacter cloacae P99 was performed to investigate the role of this residue in beta-lactam hydrolysis. This amino acid lies near the active site of the enzyme, where it can interact with the C-3 substituent of cephalosporins. Kinetic analysis of six mutant beta-lactamases with five cephalosporins showed that Ser-289 can be substituted by amino acids with nonpolar or polar uncharged side chains without altering the catalytic efficiency of the enzyme. These data suggest that Ser-289 is not essential in the binding or hydrolytic mechanism of AmpC beta-lactamase. However, replacement by Lys or Arg decreased by two- to threefold the kcat of four of the five beta-lactams tested, particularly cefoperazone, cephaloridine, and cephalothin. Three-dimensional models of the mutant beta-lactamases revealed that the length and positive charge of the side chain of Lys and Arg could create an electrostatic linkage to the C-4 carboxylic acid group of the dihydrothiazine ring of the acyl intermediate which could slow the deacylation step or hinder release of the product.  (+info)

Bacteriologic efficacies of oral azithromycin and oral cefaclor in treatment of acute otitis media in infants and young children. (2/96)

A prospective, open-label, randomized study was conducted in order to determine the bacteriologic efficacies of cefaclor and azithromycin in acute otitis media (AOM). Tympanocentesis was performed on entry into the study and 3 to 4 days after initiation of treatment. Bacteriologic failure after 3 to 4 days of treatment with both drugs occurred in a high proportion of culture-positive patients, especially in those in whom AOM was caused by Haemophilus influenzae (16 of 33 [53%] of those treated with azithromycin and 13 of 34 [52%] of those treated with cefaclor). Although a clear correlation of the persistence of the pathogen with increased MICs of the respective drugs could be demonstrated for Streptococcus pneumoniae, no such correlation was found for H. influenzae. It is proposed that susceptibility breakpoints for H. influenzae should be considerably lower than the current ones for both cefaclor and azithromycin for AOM caused by H. influenzae.  (+info)

Macrolide antibiotics inhibit nitric oxide generation by rat pulmonary alveolar macrophages. (3/96)

There is evidence that macrolide antibiotics are effective in the treatment of chronic airway inflammatory diseases, probably through actions other than their antibacterial properties. In order to determine whether macrolides affect the nitric oxide-generating system in the respiratory tract, rat pulmonary alveolar macrophages (PAMs) were studied in vitro. The release of NO was assessed by direct measurement with a specific amperometric sensor for this molecule, and the expression of type II NO synthase (NOS) messenger ribonucleic acid (mRNA) was determined by Northern blotting. Incubation of PAMs with lipopolysaccharide from Escherichia coli and recombinant human interferon-gamma caused release of NO, which was accompanied by induction of type II NOS mRNA. The release of NO was reduced by coincubation of cells with the macrolides erythromycin, clarithromycin and josamycin in a concentration-dependent manner, the maximal inhibition being 73+/-10, 81+/-6 and 84+/-9%, respectively, but was not altered by amoxycillin or cefaclor. These macrolides likewise inhibited the induction of type II NOS mRNA, whereas no inhibitory effects were observed with amoxycillin or cefaclor. These results suggest that macrolide antibiotics specifically inhibit type II NO synthase gene expression and consequently reduce NO production by rat pulmonary alveolar macrophages, which might result in attenuation of airway inflammation.  (+info)

Presence of ROB-1 beta-lactamase correlates with cefaclor resistance among recent isolates of Haemophilus influenzae. (4/96)

beta-Lactamase production in Canadian isolates of Haemophilus influenzae has remained relatively constant (25-35%) over the last decade despite increasing cefaclor resistance (MIC >/= 32 mg/L). TEM (294/324, 90.7%) and ROB-1 (30/324, 9.3%) prevalence rates among 324 isolates of H. influenzae obtained from across Canada in 1997-1998 were similar (P > 0.05) to previously published reports. However, 66. 7% (26/39) of cefaclor-resistant isolates were ROB-1-positive (P < 0. 001) and the remaining four ROB-1-positive isolates were cefaclor-intermediate (MIC 16 mg/L). Susceptibilities to loracarbef (P < 0.001) and cefprozil were also reduced in the presence of ROB-1 while the activities of cefuroxime, cefotaxime, cefixime and imipenem were similar in both TEM- and ROB-1-positive solates.  (+info)

Cefaclor, a cephalosporin antibiotic, delays gastric emptying rate by a CCK-A receptor-mediated mechanism in the rat. (5/96)

Studies in vitro suggest that cephalosporin antibiotics release the gut hormone cholecystokinin. Cholecystokinin is known to inhibit gastric emptying. Here we examine the effects of cefaclor on gastric emptying and intestinal motility. Male Sprague-Dawley rats were fitted with gastric cannulas. Following a 3-week recovery, the rate of gastric emptying of saline, peptone (4.5%) or cefaclor was determined after instillation into the gastric cannula, while intestinal transit was measured by using the propagation of arabic gum + charcoal mixture given intraduodenally. Gastric emptying of saline was significantly delayed by the addition of cefaclor (3, 10, 30 or 100 mM). The CCK-A antagonist SR-27897B (1 mg kg(-1), i.p.) reversed the delay induced by 10 mM cefaclor, whereas the CCK-B antagonist CI-988 (1 mg kg(-1), i.p.) had no significant effect. In capsaicin-treated rats, 10 mM cefaclor emptied more rapidly than in vehicle-treated animals. Thirty-minute intestinal transit was increased at 30 and 100 mM of cefaclor, while the gastric acid secretion following cefaclor instillation was no different than the group which received saline. The cephalosporin antibiotic cefaclor appears to be a potent stimulant of CCK release from gut endocrine cells, resembling the effects of peptone. Cefaclor delays gastric emptying via capsaicin-sensitive afferent pathways, which involve CCK-A receptor interaction.  (+info)

Novel mechanism of hydrolysis of therapeutic beta-lactams by Stenotrophomonas maltophilia L1 metallo-beta-lactamase. (6/96)

Stopped-flow tryptophan fluorescence under single turnover and pseudo-first-order conditions has been used to investigate the kinetic mechanism of beta-lactam hydrolysis by the Stenotrophomonas maltophilia L1 metallo-beta-lactamase. For the cephalosporin substrates nitrocefin and cefaclor and the carbapenem meropenem, a substantial quench of fluorescence is observed on association of substrate with enzyme. We have assigned this to a rearrangement event subsequent to formation of an initial collision complex. For the colorimetric compound nitrocefin, decay of this dark inter- mediate represents the overall rate-determining step for the reaction and is equivalent to decay of a previously observed state in which the beta-lactam amide bond has already been cleaved. For both cefaclor and meropenem, the rate-determining step for hydrolysis is loss of a second, less quenched state, in which, however, the beta-lactam amide bond remains intact. We suggest, therefore, that the mechanism of hydrolysis of nitrocefin by binuclear metallo-beta-lactamases may be atypical and that cleavage of the beta-lactam amide bond is the rate-determining step for breakdown of the majority of beta-lactam substrates by the L1 enzyme.  (+info)

E test for studying in vitro activity of seven antimicrobial agents against penicillin-susceptible and penicillin-resistant pneumococci. (7/96)

OBJECTIVE: To evaluate the comparative activity of seven oral antimicrobial agents against 100 strains of Streptococcus pneumoniae (S. pneumoniae). METHODS: Total 100 strains of S. pneumoniae were collected from general hospitals in Beijing from June 1996 to June 1997. E test method was used to detect the minimum inhibitory concentration (MIC) values of the following seven drugs against S. pneumoniae: penicillin, amoxicillin/clavulanate, cefaclor, cefuroxime, ceftriaxone, azithromycin and ofloxacin. The breakpoint of susceptibility categories was defined according to NCCLS. RESULTS: 74% of isolates were susceptible (S, MIC 0.06 mg/L) to penicillin, and 5% were penicillin resistant (R, MIC 2 mg/L). The intermediately resistant (I, MIC 0.1-1 mg/L) rate to penicillin was 21%. The total rates of R or I were 26% for penicillin, 6% for both amoxicillin/clavulanate and ceftriaxone, 9% for cefuroxime, 66% and 68% for azithromycin and ofloxacin respectively. Overall 94%, 94% and 91% of the pneumococcal isolates were susceptible to amoxicillin/clavulanate, ceftriaxone and cefuroxime respectively. S. pneumoniae was highly resistant to azithromycin tested as a representative of macrolides (MIC50 and MIC90 both > 256 mg/L, R rate 66%), and had a highly intermediately resistant rate to ofloxacin (I rate 62%). CONCLUSIONS: Our data suggest that in vitro activity of oral amoxicillin/clavulanate was as good as ceftriaxone and cefuroxime. It can be considered as an alternative compound in the treatment of community acquired pneumoniae and other respiratory tract infections caused by multiresistant S. pneumoniae.  (+info)

Haemophilus influenzae bla(ROB-1) mutations in hypermutagenic deltaampC Escherichia coli conferring resistance to cefotaxime and beta-lactamase inhibitors and increased susceptibility to cefaclor. (8/96)

The clinical use of cefaclor has been shown to enrich Haemophilus influenzae populations harboring cefaclor-hydrolyzing ROB-1 beta-lactamase. Such a selective process may lead to the increased use of extended-spectrum cephalosporins or beta-lactams plus beta-lactamase inhibitors and, eventually, resistance to these agents, which has not previously been observed in H. influenzae. In order to establish which bla(ROB-1) mutations, if any, could confer resistance to extended-spectrum cephalosporins and/or to beta-lactamase inhibitors, a plasmid harboring bla(ROB-1) was transformed into hypermutagenic strain Escherichia coli GB20 (DeltaampC mutS::Tn10), and this construct was used in place of H. influenzae bla(ROB-1). Strain GB20 with the cloned gene was submitted to serial passages in tubes containing broth with increasing concentrations of selected beta-lactams (cefotaxime or amoxicillin-clavulanate). Different mutations in the bla(ROB-1) gene were obtained during the passages in the presence of the different concentrations of the selective agents. Mutants resistant to extended-spectrum cephalosporins harbored either the Leu169-->Ser169 or the Arg164-->Trp164 substitution or the double amino acid change Arg164-->Trp164 and Ala237-->Thr237. ROB-1 mutants that were resistant to beta-lactams plus beta-lactamase inhibitors and that harbored the Arg244-->Cys244 or the Ser130-->Gly130 replacement were also obtained. The cefaclor-hydrolyzing efficiencies of the ROB-1 variants were strongly decreased in all mutants, suggesting that if bla(ROB-1) mutants were selected by cefaclor, this drug would prevent the further evolution of this beta-lactamase toward molecular forms able to resist extended-spectrum cephalosporins or beta-lactamase inhibitors.  (+info)

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TY - JOUR. T1 - Physicochemical properties of amphoteric β-lactam antibiotics. IV. First- and second-order degradations of cefaclor and cefatrizine in aqueous solution and kinetic interpretation of the intestinal absorption and degradation of the concentrated antibiotics. AU - Nakashima, E.. AU - Tsuji, A.. AU - Nakamura, M.. AU - Yamana, T.. PY - 1985. Y1 - 1985. N2 - A kinetic study on the degradations of cefaclor and cefatrizine was carried out at 35°C as a function of pH and initial drug concentration by the use of high-performance liquid chromatography. At constant pH and temperature, the degradation followed pseudo-first-order kinetics at the initial concentration of 5 mM. The shape of the rate-constant-pH profile of cefaclor resembled those for cefatrizine and other aminocephalosporins. At neutral pH, cefaclor was degraded via intramolecular nucleophilic attack of the α-amino group on the β-lactam moiety. The intramolecular reaction rate was very similar to that in the cases of ...
Cefaclor may also be used for other purposes not listed in this medication guide. What is the most important information I should know about Ceclor (cefaclor)? Do not take this medication if you are allergic to cefaclor, or to similar antibiotics, such as Ceftin, Cefzil, Duricef, Fortaz, Keflex, Omnicef, Spectracef, Suprax, and others.
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The relationship between the growth rate and the kill rate was used to evaluate and to compare the in vitro bactericidal activities of cefdinir, a new oral cephalosporin, and cefaclor against Streptococcus pneumoniae and beta-lactamase-producing strains of Haemophilus influenzae. These frequently encountered pathogens of community-acquired respiratory tract infections are usually susceptible to both drugs. The MIC ranges for cefdinir and cefaclor were, respectively, 0.03 to 0.06 and 0.25 to 0.5 micrograms/ml for S. pneumoniae and 0.25 and 4 to 8 micrograms/ml for H. influenzae. The colony counts (CFU per milliliter) measured after 6 h of exposure to a range of antibiotic concentrations in broth were plotted against the colony count of the control culture over the same period of time. Higher kill rates versus bacterial growth rates were noted for S. pneumoniae for both drugs (positive balance). Conversely, lower kill rates versus growth rates were noted for H. influenzae for both drugs (negative ...
Cefaclor - Cefaclor is a second-generation cephalosporin antibiotic used for treating bacterial infections. It is a broad spectrum antibiotic effective for the treatment of otitis media, lower respiratory tract infections including pneumonia, pharyngitis and tonsillitis, biliary-tract infections, peritonitis and urinary tract infections, skin and skin structure infections.
This is a randomized, open-label, parallel group, multicenter study to determine the effectiveness and safety of 488 mg of levofloxacin (once daily by mouth for 5 - 7 days) compared with 250 mg of cefaclor (every 8 hours for 7 - 10 days) in adults with chronic bronchitis experiencing rapid onset of worsening of symptoms caused by bacterial infection. The study consists of 3 visits: one visit for screening and enrollment, and 2 visits for assessment of safety and effectiveness (one visit on Days 3 - 5 of the study and one visit [post-therapy] 5 - 7 days after the last dose of the study drug). The total duration of patient participation in the study is approximately 2 weeks. Levofloxacin and cefaclor are antibacterial agents used for the treatment of many types of infections, including infections with a rapid onset and brief duration caused by bacteria. The primary assessment of effectiveness in this study is the microbiologic response to treatment (the rate of elimination of disease-causing ...
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Cefaclor is a cephalosporin antibiotic prescribed for treatment of ear infections, laryngitis, bronchitis, urinary tract and skin infections.
TY - JOUR. T1 - Comparative clinical study of ciprofloxacin and cefaclor in the treatment of respiratory tract infections. AU - Kobayashik, Hiroyuki. AU - Takamura, Enji. AU - Takeda, Hiroaki. AU - Kono, Kota. AU - Saito, Akira. AU - Tomizawa, Masumi. AU - Nakayama, Ichiro. AU - Hiraga, Yohmei. AU - Kikuchi, Kohki. AU - Yamamoto, Asako. AU - Takebe, Kazuo. AU - Kumasakak, Yoshihiro. AU - Aoyagi, Azumi. AU - Tamura, Toyokazu. AU - Sekino, Keiichi. AU - Endo, Katsumi. AU - Irie, Tatsuro. AU - Sagara, Morio. AU - Okamoto, Katsuhiro. AU - Tamura, Masao. AU - Konishi, Kazuki. AU - Daibo, Ataru. AU - Kuramitsu, Hiroshi. AU - Gomi, Kazutoshi. AU - Itakura, Kotaro. AU - Sato, Nobuhisa. AU - Tanifuji, Kazuo. AU - Takishima, Tamotsu. AU - Ida, Shiroh. AU - Ohno, Isao. AU - Konno, Kiyoshi. AU - Oizumi, Kotaro. AU - Aonuma, Seiichi. AU - Hayashi, Izumi. AU - Katsu, Masataka. AU - Okui, Shinji. AU - Fukui, Toshio. AU - Yokose, Takashi. AU - Toyota, Takeo. AU - Kawai, Mieko. AU - Yamagata, Hajime. AU - ...
Cefaclor is a cephalosporin antibiotic prescribed for treatment of ear infections, laryngitis, bronchitis, urinary tract and skin infections.
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Information about taking cefaclor, an antibiotic to treat bacterial infections, including dose, side effects and if you can drink alcohol
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice. ...
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice. ...
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Take this medicine by mouth. Follow the directions on the prescription label. You can take it with or without food. If it upsets your stomach it may help to take it with food. Take your medicine at regular intervals. Do not take it more often than directed. Take all of your medicine as directed even if you think you are better. Do not skip doses or stop your medicine early.. Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for selected conditions, precautions do apply.. ...
Take this medication exactly as your doctor has prescribed it. You must carefully follow all directions given to you. Avoid exceeding your dose or taking the medication longer than it was advised by your doctor. Swallow it whole with a full glass of water. This medication is not chewed, crushed or broken while taking. This is an extended-release tablet aimed to release medicine slowly after you have swallowed it. If you break the tablet it can cause too much of the medicine to be released right away, which is not desirable. Generally the recommended dosage is 250-500 mg taken every eight hours or 375-500 mg taken every twelve hours. To treat gonorrhea you should take 3,000 mg of the medication right away. Treatment course continues 7-10 days ...
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Detailed Loracarbef dosage information for adults and children. Includes dosages for Sinusitis, Bronchitis, Cystitis and more; plus renal, liver and dialysis adjustments.
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Learn about the potential side effects of Ceclor CD (cefaclor). Includes common and rare side effects information for consumers and healthcare professionals.
[119 Pages Report] Check for Discount on Japan Cefprozil Market Report 2016 report by QYResearch Group. Notes: Sales, means the sales volume of Cefprozil Revenue, means...
Cefprozil comes as a tablet or an oral liquid that is taken to treat certain bacterial infections. This eMedTV Web site takes a look at a number of topics related to this prescription antibiotic, including how it works, side effects, and safety issues.
Medical information for Cefprozil on Pediatric Oncall including Mechanism, Indication, Contraindications, Dosing, Adverse Effect, Interaction, Hepatic Dose.
TY - JOUR. T1 - Laboratory and clinical studies of loracarbef. AU - Irabu, Yuei. AU - Inadome, Jun. AU - Fukuhara, Hiroshi. AU - Nakamura, Hiroaki. AU - Kaneshima, Hiroshi. AU - Shimoji, Katsuyoshi. AU - Kitsukawa, Keizou. AU - Shigeno, Yoshiteru. AU - Saito, Atsushi. AU - Furugen, Kyouko. AU - Nakasone, Isamu. AU - Taira, Shinko. AU - Kusano, Nobutika. AU - Hokama, Seitetsu. AU - Hokama, Tyoutetsu. PY - 1993. Y1 - 1993. N2 - We performed bacteriological and clinical evaluations of loracarbef (LCBF), a new oral carbacephem, in respiratory tract infections, with the following results. 1) Antimicrobial activity: The minimum inhibitory concentrations (MICs) of LCBF were measured in 302 clinically isolated strains, and compared with those of cefaclor, cefotiam, cefixime, cefteram and amoxicillin, using the MIC-2000 system. LCBF had wide antimicrobial activity against clinically isolated strains except methicillin-resistant Staphylococcus aureus, Enterococcus faecalis, Enterobacter cloacae, Serratia ...
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Ceclor is a cephalosporin antibiotic prescribed for treatment of ear infections, laryngitis, bronchitis, urinary tract and skin infections.
Ceclor is a cephalosporin antibiotic prescribed for treatment of ear infections, laryngitis, bronchitis, urinary tract and skin infections.
Ceclor is a cephalosporin antibiotic prescribed for treatment of ear infections, laryngitis, bronchitis, urinary tract and skin infections.
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A DOUBLE BLIND COMPARATIVE STUDY ON THE EFFICACY OF S6472, CEFACLOR AND AMOXICILLIN, IN THE TREATMENT OF BACTERIAL PNEUMONIA (1986 ...
Product name: Ceclor. Active substance: Cefaclor. Thumbnail sketch: Generic Ceclor is used in the treatment of ear, nose, throat, respiratory tract, urinary tract, and skin infections caused by specific bacteria, including staph, strep, and E. coli. Uses include treatment of sore or strep throat, pneumonia, and tonsillitis.. Similar Titles: Ceclor / Raniclor. Manufacturer: Baroque Pharma / Ranbaxy. Place an order: Follow this link. Payment method: Visa / Wiretransfer. Delivery Time: 5-7 business days by Courier Service or 10-21 business days by Standard International Airmail. Bonus options: Really amazing prices and Free bonuses! Discount system! No prescription required! Fast worldwide shipping! 30 days money back guarantee! Free AirMail & Courier shipping for large orders. Customer support available 24/7! Many payment options: Visa, Amex, MasterCard, eCheck, Wire transfer.. ...
TM, Davey PG. Factors associated with trimeth- of purulent chronic bronchitis. Postgrad Med J. 50. Porteous DM, Berger TG. Severe cutaneous drug oprim-resistant bacteria isolated from urine reactions (Stevens-Johnson syndrome and toxic samples. J Antimicrob Chemother. 1999;43:841- 84. Anderson G, Williams L, Pardoe T, Peel ET. Co- epidermal necrolysis) in human immunodefi- trimoxazole versus cefaclor in acute on chronic ciency virus infection. Arch Dermatol. 1991;127: 68. Wright SW, Wrenn KD, Haynes ML. Trimetho- bronchitis. J Antimicrob Chemother. 1981;8: prim-sulfamethoxazole resistance among uri- 51. Greenberg S, Reiser IW, Chou SY. Hyperkale- nary coliform isolates. J Gen Intern Med. 1999; 85. Hughes DT. The use of combinations of trimeth- mia with high-dose trimethoprim-sulfamethoxa- oprim and sulphonamides in the treatment of zole therapy. Am J Kidney Dis. 1993;22:603- 69. Zhanel GG, Karlowsky JA, Harding GKM, et al, chest infections. J Antimicrob Chemother. 1983; for the Canadian Urinary ...
TM, Davey PG. Factors associated with trimeth- of purulent chronic bronchitis. Postgrad Med J. 50. Porteous DM, Berger TG. Severe cutaneous drug oprim-resistant bacteria isolated from urine reactions (Stevens-Johnson syndrome and toxic samples. J Antimicrob Chemother. 1999;43:841- 84. Anderson G, Williams L, Pardoe T, Peel ET. Co- epidermal necrolysis) in human immunodefi- trimoxazole versus cefaclor in acute on chronic ciency virus infection. Arch Dermatol. 1991;127: 68. Wright SW, Wrenn KD, Haynes ML. Trimetho- bronchitis. J Antimicrob Chemother. 1981;8: prim-sulfamethoxazole resistance among uri- 51. Greenberg S, Reiser IW, Chou SY. Hyperkale- nary coliform isolates. J Gen Intern Med. 1999; 85. Hughes DT. The use of combinations of trimeth- mia with high-dose trimethoprim-sulfamethoxa- oprim and sulphonamides in the treatment of zole therapy. Am J Kidney Dis. 1993;22:603- 69. Zhanel GG, Karlowsky JA, Harding GKM, et al, chest infections. J Antimicrob Chemother. 1983; for the Canadian Urinary ...
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Cefprozil is used to treat bacterial infections in many different parts of the body. It belongs to the class of medicines known as cephalosporin antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections. ...
Get an overview of CEFPROZIL (powder, for suspension), including warnings and precautions, directions, and the names of other drugs and products that include the same medication.
... is a synthetic "carba" analog of cefaclor, and is more stable. Loracarbef received FDA approval in 1991 and it was ...
Zaike is the brand name for its cefaclor in dry suspension antibiotics for the treatment of infections. Simcere Kechuanning is ...
Cefaclor however has a Cl group at position C-3 which gives it better binding to PBP and thus better antimicrobial activity. ... The 7-phenyl-glycine makes it orally available and the chlorine at position C-3 makes it as active as Cefaclor. An important ... There is not an agreement on classifying Cefaclor as a first generation cephalosporin because of the Cl group at the C-3 ...
For example, the fourth generation of cephalosporins is not recognized as such in Japan.[citation needed] In Japan, cefaclor is ... but the use of cefaclor, cefadrocil, cefalexin, and cefradine should be avoided. Overall, the research shows that all beta ...
Agents that have been implicated in serum sickness-like reactions include cefaclor, amoxicillin, sulfonamides, tetracyclines, ...
... cefaclor, piracetam, vaccines, and antidiabetic drugs. The antidiabetic sulphonylurea glimepiride, in particular, has been ...
... cefaclor (INN) cefadroxil (INN) Cefadyl cefalexin (INN) cefaloglycin (INN) cefalonium (INN) cefaloram (INN) cefaloridine (INN) ...
Ticarcillin Azlocillin Mezlocillin Piperacillin Cefazolin Cephalexin Cephalosporin C Cephalothin Cefapirin Cefaclor Cefamandole ...
... second generation cephalosporins such as cefaclor Klebsiella pneumoniae Escherichia coli Pseudomonas aeruginosa - ciprofloxacin ...
... cefaclor, cefazoline, cefuroxime, and cefdinir), oxacillin, and most macrolides. Most isolated P. penneri strains are multiple- ...
Cefacetrile J01DB11 Cefroxadine J01DB12 Ceftezole J01DC01 Cefoxitin J01DC02 Cefuroxime J01DC03 Cefamandole J01DC04 Cefaclor ...
... cefaclor 1980 - cefmetazole 1980 - cefotaxime 1980 - piperacillin 1981 - co-amoxiclav (amoxicillin/clavulanic acid) 1981 - ...
... has also been reported to cause a serum sickness-like reaction in children. Cefaclor is contraindicated in case of ... Cefaclor is active against many bacteria, including both Gram-negative and Gram-positive organisms. Cefaclor is frequently used ... www.toku-e.com/Assets/MIC/Cefaclor.pdf Hebert A, Sigman E, Levy M (1991). "Serum sickness-like reactions from cefaclor in ... Cefaclor is passed into the breast milk in small quantities, but is generally accepted to be safe to take during breastfeeding ...
InChI=1S/C20H22N4O10S/c1-9(25)33-10(2)34-19(28)15-11(7-32-20(21)29)8-35-18-14(17(27)24(15)18)22-16(26)13(23-30-3)12-5-4-6-31-12/h4-6,10,14,18H,7-8H2,1-3H3,(H2,21,29)(H,22,26)/b23-13-/t10?,14-,18-/m1/ ...
The production of benzylpenicillin involves fermentation, recovery and purification of the penicillin.[10] The fermentation process of the production of benzylpencillin is about obtaining the product. The presence of the product in solution inhibits the reaction and reduces the product rate and yield. Thus, in order to obtain the most product and increase the rate of reaction the product, would be continuously extracted out.[11] This is done by having the mold with either glucose, sucrose, lactose, startch, or detrin, nitrate, ammonium salt, corn steep liquor, peptone, meat or yeast extract, and little amounts of inorganic salts.[12] The recovery of the benzylpencillin is the most important part of the production process because it affects the purification steps if done wrong.[10] There are many different types of techniques to recover benzyl penicillin, aqueous two-phase extraction, liquid membrane extraction, microfiltration technique, and solvent subulation[10] Extraction is more commonly ...
... , sold under the brandname Merrem among others, is a broad-spectrum antibiotic used to treat a variety of bacterial infections.[1] Some of these include meningitis, intra-abdominal infection, pneumonia, sepsis, and anthrax.[1] It is given by injection into a vein.[1] Common side effects include nausea, diarrhea, constipation, headache, rash, and pain at the site of injection.[1] Serious side effects include Clostridium difficile infection, seizures, and allergic reactions including anaphylaxis.[1] Those who are allergic to other β-lactam antibiotics are more likely to be allergic to meropenem.[1] Use in pregnancy appears to be safe.[1] It is in the carbapenem family of medications.[1] Meropenem usually results in bacterial death through blocking their ability to make a cell wall.[1] It is more resistant to breakdown β-lactamase producing bacteria.[1] Meropenem was patented in 1983.[2] It was approved for medical use in the United States in 1996.[1] It is on the World Health ...
InChI=1S/C14H15N5O5S2/c1-5-3-25-12-8(11(21)19(12)9(5)13(22)23)17-10(20)7(18-24-2)6-4-26-14(15)16-6/h4,8,12H,3H2,1-2H3,(H2,15,16)(H,17,20)(H,22,23)/b18-7-/t8-,12-/m1/ ...
Bonow RO, Carabello BA, Kanu C, et al. (August 2006). "ACC/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (writing committee to revise the 1998 Guidelines for the Management of Patients With Valvular Heart Disease): developed in collaboration with the Society of Cardiovascular Anesthesiologists: endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons". Circulation. 114 (5): e84-231. doi:10.1161/CIRCULATIONAHA.106.176857. PMID 16880336 ...
Penicillin V is sometimes used in the treatment of odontogenic infections.. It is less active than benzylpenicillin (penicillin G) against Gram-negative bacteria.[9][10] Phenoxymethylpenicillin has a range of antimicrobial activity against Gram-positive bacteria that is similar to that of benzylpenicillin and a similar mode of action, but it is substantially less active than benzylpenicillin against Gram-negative bacteria.[9][10]. Phenoxymethylpenicillin is more acid-stable than benzylpenicillin, which allows it to be given orally.. Phenoxymethylpenicillin is usually used only for the treatment of mild to moderate infections, and not for severe or deep-seated infections since absorption can be unpredictable. Except for the treatment or prevention of infection with Streptococcus pyogenes (which is uniformly sensitive to penicillin), therapy should be guided by bacteriological studies (including sensitivity tests) and by clinical response.[11] People treated initially with parenteral ...
The in vitro activity of ceftolozane-tazobactam has been examined in five surveillance studies of isolates from Europe and North America.[8] In these studies, ceftolozane-tazobactam was notable for its activity against Pseudomonas aeruginosa, a moderately common cause of hospital-acquired infections that is commonly multi-drug resistant. Ninety percent of P. aeruginosa isolates were inhibited by a ceftolozane-tazobactam at a concentration of 4 μg/mL (MIC90), making it the most potent anti-pseudomonal antibiotic in clinical use. In these same studies, ceftolozane-tazobactam exhibited MIC90 values of ,1 μg/mL for Escherichia coli, Citrobacter koseri, Morganella morganii, Proteus mirabilis, Salmonella species, and Serratia marcescens. Somewhat poorer activity is observed for the Klebsiella and Enterobacter species, with the MIC90 for extended spectrum beta-lactamase (ESBL) expressing Klebsiella pneumonia being ,32 μg/mL. ...
A set of multienzymes (peptide synthase CepA, CepB, and CepC) are responsible for assembling the heptapeptide. (Figure 2). The organization of CepA, CepB, and Cep C closely resembles other peptide synthases such as those for surfactin (SrfA1, SrfA2, and SrfA3) and gramicidin (GrsA and GrsB).[41] Each peptide synthase activates codes for various amino acids to activate each domain. CepA codes for modules 1, 2, and 3. CepB codes for modules 4, 5, and 6, and CepC codes for module 7. The three peptide synthases are located at the start of the region of the bacterial genome linked with antibiotic biosynthesis, and span 27 kb.[41]. After the linear heptapeptide molecule is synthesized, vancomycin has to undergo further modifications, such as oxidative cross-linking and glycosylation, in trans[clarification needed] by distinct enzymes, referred to as tailoring enzymes, to become biologically active (Figure 3). To convert the linear heptapeptide, eight enzymes, open reading frames (ORFs) 7, 8, 9, 10, ...
InChI=1S/C16H21N7O7S3/c1-22-15(19-20-21-22)33-4-7-3-32-14-16(30-2,13(29)23(14)10(7)12(27)28)18-9(24)6-31-5-8(17)11(25)26/h8,14H,3-6,17H2,1-2H3,(H,18,24)(H,25,26)(H,27,28)/t8-,14-,16+/m1/s1 ‹See TfM› ...
... (SEF-di-nir) is a third-generation oral cephalosporin antibiotic sold under the brand names Cefzon and Omnicef. As of 2008, cefdinir, as Omnicef, was the highest-selling cephalosporin antibiotic in the United States, with more than US$585 million in retail sales of its generic versions alone.[1] Cefdinir is structurally similar to cefixime. It was discovered by Fujisawa Pharmaceutical Co., Ltd. (now Astellas) and introduced in 1991 under the brand name Cefzon.[2][3] Warner-Lambert licensed this cephalosporin for marketing in US from Fujisawa.[4] Abbott obtained U.S. marketing rights to Omnicef (cefdinir) in December 1998 through an agreement with Warner-Lambert Company.[5] It was approved by FDA on Dec 4, 1997.[6] It is available in US as Omnicef by Abbott Laboratories and in India as Cednir by Abbott, Kefnir by Glenmark, Cefdair by Xalra Pharma and Cefdiel by Ranbaxy. ...
Ceftolozane exerts bactericidal activities against susceptible gram-negative and gram-positive infections by inhibiting essential penicillin-binding proteins (PBPs), which are required for peptidoglycan cross-linking for bacterial cell wall synthesis, resulting in inhibition of cell wall synthesis and subsequent cell death. Ceftolozane is an inhibitor of PBPs of Pseudomonas aeruginosa (e.g. PBP1b, PBP1c, and PBP3) and E. coli (e.g., PBP3).[6][7] Tazobactam is a potent β-lactamase inhibitor of most common class A and C β-lactamases. Tazobactam has little clinically relevant in vitro activity against bacteria due to its reduced affinity to penicillin-binding proteins; however, it is an irreversible inhibitor of some β-lactamases (certain penicillinases and cephalosporinases) and can covalently bind to some chromosomal and plasmid-mediated bacterial beta-lactamases.[6] The addition of tazobactam strengthens the therapeutic response to ceftolozane, giving it the ability to treat a broader range ...
... is a second-generation cephalosporin antibiotic. It can be used to treat ear infections, skin infections, and other bacterial infections.[citation needed] It comes as a tablet and as a liquid suspension. Although there is a widely quoted cross-allergy risk of 10% between cephalosporins and penicillin, an article[1] has shown no increased risk for cross-allergy for cefprozil and several other second-generation or later cephalosporins. It was patented in 1983 and approved for medical use in 1992.[2] ...
cephalosporin antibiotics such as cefaclor (Ceclor), cefuroxime (Ceftin), cefadroxil (Duricef), cephalexin (Keflex), and others ...
সেফাক্লর (Cefaclor). *সেফুরোক্সিম (Cefuroxime). *সেফামান্ডল (Cefamendole). দ্বিতীয় প্রজন্মের সেফামাইসিন[সম্পাদনা]. এন্টি ...
Cefaclor • Cefoxitină • Cefotetan • Cefuroximă (axetil) • Cefamandol‡ • Cefprozil • Cefonicid‡ • Loracarbef‡ (carbacefemă). ...
Cefaclor • Cefamandole • Cefminox • Cefonicid • Ceforanide • Cefotiam • Cefprozil • Cefbuperazone • Cefuroxime • Cefuzonam • ...
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Cefaclor: learn about side effects, dosage, special precautions, and more on MedlinePlus ... Take cefaclor until you finish the prescription, even if you feel better. If you stop taking cefaclor too soon or skip doses, ... Before taking cefaclor,. *tell your doctor and pharmacist if you are allergic to cefaclor, other cephalosporin antibiotics such ... Take cefaclor exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. ...
Cefaclor has also been reported to cause a serum sickness-like reaction in children. Cefaclor is contraindicated in case of ... Cefaclor is active against many bacteria, including both Gram-negative and Gram-positive organisms. Cefaclor is frequently used ... www.toku-e.com/Assets/MIC/Cefaclor.pdf Hebert A, Sigman E, Levy M (1991). "Serum sickness-like reactions from cefaclor in ... Cefaclor is passed into the breast milk in small quantities, but is generally accepted to be safe to take during breastfeeding ...
Cefaclor (UNII: 69K7K19H4L) (Cefaclor Anhydrous - UNII:3Z6FS3IK0K) Cefaclor Anhydrous. 125 mg in 5 mL. ... Cefaclor (UNII: 69K7K19H4L) (Cefaclor Anhydrous - UNII:3Z6FS3IK0K) Cefaclor Anhydrous. 187 mg in 5 mL. ... Cefaclor (UNII: 69K7K19H4L) (Cefaclor Anhydrous - UNII:3Z6FS3IK0K) Cefaclor Anhydrous. 250 mg in 5 mL. ... Cefaclor (UNII: 69K7K19H4L) (Cefaclor Anhydrous - UNII:3Z6FS3IK0K) Cefaclor Anhydrous. 375 mg in 5 mL. ...
Table 2: Acceptable Quality Control Ranges for Cefaclor Table 2: Acceptable Quality Control Ranges for Cefaclor QC Strain. ... Table 1: Susceptibility Test Interpretive Criteria for Cefaclor Table 1: Susceptibility Test Interpretive Criteria for Cefaclor ... are resistant to cefaclor. Cefaclor is inactive against methicillin-resistant staphylococci. -lactamase-negative, ampicillin- ... This procedure uses paper disks impregnated with 30-mcg cefaclor to test the susceptibility of microorganisms to cefaclor. The ...
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Cefaclor-associated serum sickness-like reaction. CMAJ October 01, 1996 155 (7) 913-914; ...
Find patient medical information for Cefaclor Oral on WebMD including its uses, side effects and safety, interactions, pictures ... cefaclor 250 mg capsule. color. pink,blue. shape. oblong. imprint. KRC, KRC. This medicine is a pink blue, oblong, capsule ... cefaclor 500 mg capsule. color. purple,gray. shape. oblong. imprint. West- Ward, 986. This medicine is a purple gray, oblong, ... cefaclor 250 mg capsule. color. white,purple. shape. oblong. imprint. West- Ward, 985. This medicine is a white purple, oblong ...
Find patient medical information for Cefaclor Oral on WebMD including its uses, side effects and safety, interactions, pictures ... cefaclor ER 500 mg tablet,extended release,12 hr. color. dark blue. shape. oval. imprint. 93, 1087. This medicine is a dark ... How to use Cefaclor ER. Take this medication by mouth with a meal, usually every 12 hours, or as directed by your doctor. ... Cefaclor may cause live bacterial vaccines (such as typhoid vaccine) to not work as well. Do not have any immunizations/ ...
In summary, we report a case of an anaphylactic reaction to cefaclor in the pediatric population. Because cefaclor is widely ... Our patient gradually developed hypersensitivity to cefaclor; his first three exposures to cefaclor were without significant ... and loss of consciousness immediately after cefaclor ingestion, requiring immediate treatment. This reaction to cefaclor is ... 1980) Cefaclor in the treatment of otitis media and pharyngitis in children. Am J Dis Child. 134:560-563. ...
Information about taking cefaclor, an antibiotic to treat bacterial infections, including dose, side effects and if you can ... Who shouldnt take cefaclor?. Cefaclor is not suitable for:. *People who have ever had an allergic reaction to penicillin or ... How do I take cefaclor, and how often?. The dose of cefaclor, how often to take it and how long to take it for depends on the ... How does cefaclor work?. Cefaclor is a type of antibiotic called a cephalosporin. It works by interfering with the formation of ...
Cefaclor) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related ... Cefaclor for Oral Suspension, USP. Strength Package Size (when mixed). Water Volume to Add. Anhydrous Cefaclor/5 mL (approx. ... The effect of cefaclor on labor and delivery is unknown.. Nursing Mothers. Small amounts of cefaclor have been detected in ... CEFACLOR. (Cefaclor) for Oral Suspension, USP. To reduce the development of drug-resistant bacteria and maintain the ...
NOVO CEFACLOR, 250MG, CAPSULE. Common uses. This medication contains an antibiotic from the cephalosporin family. Typically, it ...
Capsules; Oral; Cefaclor Monohydrate 500 mg*Suspension; Oral; Cefaclor Monohydrate 125 mg / 5 ml*Suspension; Oral; Cefaclor ... Suspension; Oral; Cefaclor Monohydrate 250 mg / 5 ml*Tablets, Dispersible; Oral; Cefaclor Monohydrate 125 mg*Tablets, ...
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  • Cefaclor is in a class of medications called cephalosporin antibiotics. (medlineplus.gov)
  • Antibiotics such as cefaclor will not work for colds, flu, or other viral infections. (medlineplus.gov)
  • If you stop taking cefaclor too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics. (medlineplus.gov)
  • Cefaclor belongs to the family of antibiotics known as the cephalosporins (cefalosporins). (wikipedia.org)
  • Cefaclor cannot be administered in patients with hypersensitivity to the medication and other beta-lactam antibiotics. (arfamed.com)
  • Cefaclor, an orally active cephalosporin in clinical practice, belongs to the group of β-lactam antibiotics. (ijpsonline.com)
  • Amoxicillin and cefaclor are two of the widely used β-lactam antibiotics in the treatment of urinary tract infections. (aspetjournals.org)
  • Amoxicillin and cefaclor competitively inhibited hPepT2-mediated [ 3 H]glycylsarcosine uptake ( K i = 733 and 65 μM, respectively), whereas much lower affinity for hPepT1 was observed with both antibiotics. (aspetjournals.org)
  • Cefaclor is in a group of drugs called cephalosporin (SEF a low spor in) antibiotics. (pharmacy-network.com)
  • Some people who are allergic to penicillin antibiotics may not be able to take cefaclor, so make sure your doctor knows if you have ever had an. (aqbt.info)
  • If a dog is allergic cefaclor wie lange nehmen to penicillin, oxacillin, nafcillin or any other penicillin-based antibiotics, the dog will also be allergic to amoxicillin. (antonsword.com)
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  • Lowering cefaclor tabletas 500 mg uric acid levels may also help your kidneys.Probenecid is sometimes used along with penicillin antibiotics (e.g., penicillin, ampicillin, nafcillin) to increase antibiotic blood levels. (antonsword.com)
  • Food, drug, insect sting allergy, and anaphylaxis IgE-mediated hypersensitivity to cephalosporins: Cross-reactivity and tolerability of alternative.Do not take this medication if you are allergic to cefaclor,.Antibiotics, which can be used as alternative to penicillin in case of allergy.Includes: indications, dosage, adverse reactions, pharmacology and more. (usedcarloancalculator.ml)
  • Cefaclor comes as a capsule, an extended-release (long-acting) tablet, and a suspension (liquid) to take by mouth. (medlineplus.gov)
  • Also tell your doctor if you are allergic to any of the ingredients in cefaclor capsules, extended release tablets, or suspension. (medlineplus.gov)
  • To reduce the development of drug-resistant bacteria and maintain the effectiveness of Cefaclor for Oral Suspension and other antibacterial drugs, Cefaclor for Oral Suspension, USP, should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. (nih.gov)
  • After mixing, each 5 mL of Cefaclor for Oral Suspension will contain cefaclor monohydrate equivalent to 125 mg (0.34 mmol), 187 mg (0.51 mmol), 250 mg (0.68 mmol), or 375 mg (1.0 mmol) anhydrous cefaclor. (nih.gov)
  • At the age of 2 years, he developed generalized hives 1 day after ingesting cefaclor suspension for otitis media. (aappublications.org)
  • The solvent blend water:propylene glycol (20:80) in which the drug exhibited maximum solubility was used as the reconstituting medium for formulation of dry suspension of cefaclor. (ijpsonline.com)
  • The aim of the present study is to determine the solubility parameter of cefaclor by evaluating the solubility of cefaclor in different blends of water:propylene glycol (PG) to overcome the problem of solubility and hydrolytic instability, and to design and formulate dry suspension for reconstitution of cefaclor as a dual pack system and compare with marketed formulation. (ijpsonline.com)
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  • Cefaclor, USP, is a semisynthetic cephalosporin antibiotic for oral administration. (nih.gov)
  • Cefaclor is well absorbed after oral administration to fasting subjects. (nih.gov)
  • Cefaclor, an oral second-generation cephalosporin with a β-lactam ring, is used against various infectious diseases of the respiratory tract, especially in children. (aappublications.org)
  • However if you're taking a particularly high dose or long course of cefaclor your doctor might ask you to monitor your baby for any signs of stomach upset or oral thrush infection. (netdoctor.co.uk)
  • The relationship between the growth rate and the kill rate was used to evaluate and to compare the in vitro bactericidal activities of cefdinir, a new oral cephalosporin, and cefaclor against Streptococcus pneumoniae and beta-lactamase-producing strains of Haemophilus influenzae. (asm.org)
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  • The subjects received either amoxicillin or cefaclor at a dose of 40 mg/kg/day in three doses for 10 days. (nih.gov)
  • The clinical cure rate with amoxicillin was 81%, compared to 78% with cefaclor. (nih.gov)
  • three had been given amoxicillin, and one cefaclor. (nih.gov)
  • Interactions of amoxicillin and cefaclor with human renal organic anion and peptide transporters. (alfa.com)
  • The objective of the current study was to examine the kinetics of amoxicillin and cefaclor interactions with human renal transporters human organic anion transporter 1 (hOAT1), human peptide transporter 1 (hPepT1), and human peptide transporter 2 (hPepT2) in detail, both as substrates and as inhibitors. (aspetjournals.org)
  • Amoxicillin and cefaclor inhibited hOAT1-mediated [ 3 H] para -aminohippuric acid uptake ( K i = 11.0 and 1.15 mM, respectively). (aspetjournals.org)
  • Direct uptake studies demonstrated that amoxicillin and cefaclor were transported by hPepT1 and hPepT2. (aspetjournals.org)
  • Kinetic analysis showed that hPepT2-mediated uptake of both drugs was saturable with K m of 1.04 mM for amoxicillin and 70.2 μM for cefaclor. (aspetjournals.org)
  • hPepT2, and to a lesser extent hPepT1, may play an important role in apical transport of amoxicillin and cefaclor in the renal tubule. (aspetjournals.org)
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  • The safety of a hora in a cephalosporin-allergic belladonna depends on Amoxicillin, cefaclor, cefazolin, and is cefaclor a penicillins G and V, which do not. (aqbt.info)
  • a patient who has an allergic reaction to amoxicillin is likely to have a similar reaction to the cefaclor. (usedcarloancalculator.ml)
  • Cefaclor is frequently used against bacteria responsible for causing skin infections, otitis media, urinary tract infections, and others. (wikipedia.org)
  • Two months later, the patient redeveloped otitis media, and unfortunately, ignorant to the previous reaction, cefaclor was prescribed. (aappublications.org)
  • Cefaclor is designed for treatment of Otitis Media, lower RTI (Respiratory Tract Infection), Tonsillitis, Pharyngitis, UTI and other infections developed from strains of specific bacteria that are susceptible. (paidtobuy.com)
  • PD-Rx Pharmaceuticals, Inc.: Cefaclor is indicated in the treatment of the following infections when caused by susceptible strains of the designated.An allergic reaction involving the mouth, throat or difficulty breathing is a medical emergency and should be treated by a physician.C, 63-69 An open study to compare azithromycin with cefaclor in the treatment of children with acute otitis media. (usedcarloancalculator.ml)
  • In patients with reduced renal function, the serum half-life of cefaclor is slightly prolonged. (nih.gov)
  • Cefaclor may be administered in the presence of impaired renal function. (rxlist.com)
  • This benet, however, was offset by an infectious sexually transmitted infections symptoms lasix renal scan protocol and urogenital cefaclor urinary tract infection atrophy. (iahf.com)
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  • This dose should be reduced according to creatinine clearance (see Renal cefaclor einnahme vergessen impairment below). (ncca.am)
  • Cefaclor, sold under the trade name Ceclor among others, is a second-generation cephalosporin antibiotic used to treat certain bacterial infections such as pneumonia and infections of the ear, lung, skin, throat, and urinary tract. (wikipedia.org)
  • Ceclor (Cefaclor) is a cephalosporin antibiotic used to treat bacterial infections. (medformula.com)
  • This test is used to measure a person's allergic reaction to Cefaclor , a type of antibiotic used to treat a variety of infections. (requestatest.com)
  • Cefaclor, also known as cefachlor or cefaclorum (brand names Ceclor, Distaclor, Keflor, Raniclor), is a second-generation cephalosporin antibiotic used to treat certain infections caused by bacteria such as pneumonia and ear, lung, skin, throat, and urinary tract infections. (drugsupdate.com)
  • Cefaclor is a second-generation cephalosporin antibiotic used to treat infections caused by Gram-positive and Gram-negative bacteria such as pneumonia, strep throat. (geminihomestay.tk)
  • Cefaclor ER is an antibiotic used to treat certain bacterial infections of the respiratory (lung) tract, and throat, tonsils, or skin infections.Penicillin and Cephalosporins. (usedcarloancalculator.ml)
  • Resistance to cefaclor is primarily through hydrolysis of beta-lactamases, alteration of penicillin-binding proteins (PBPs) and decreased permeability. (nih.gov)
  • Subsequently we tested the patient for penicillin and cefaclor. (aappublications.org)
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  • Cefaclor binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death. (drugsupdate.com)
  • Cefaclor is active against many bacteria, including both Gram-negative and Gram-positive organisms. (wikipedia.org)
  • Cefaclor is an antibiotic medicine prescribed to treat various infections caused by bacteria . (netdoctor.co.uk)
  • Cefaclor is a broad-spectrum antibiotic, which means it kills a wide variety of different types of bacteria. (netdoctor.co.uk)
  • To make sure the bacteria causing an infection are susceptible to cefaclor your doctor may take a tissue sample , for example a swab from the throat or skin, or a urine or sputum sample. (netdoctor.co.uk)
  • Levofloxacin and cefaclor are antibacterial agents used for the treatment of many types of infections, including infections with a rapid onset and brief duration caused by bacteria. (clinicaltrials.gov)
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  • If you forget to take a dose of cefaclor at the correct time, take it as soon as you remember and then space the rest of your doses over the remaining part of the day. (netdoctor.co.uk)
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  • Cefaclor is contraindicated in case of hypersensitivity (i.e. allergy) to cephalosporins. (wikipedia.org)
  • As with other cephalosporins, the bactericidal action of cefaclor results from inhibition of cell-wall synthesis. (nih.gov)
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