An enzyme that catalyzes the formation of PHOSPHATIDYLINOSITOL and CMP from CDP-DIACYLGLYCEROL and MYOINOSITOL.
A class of enzymes that transfers substituted phosphate groups. EC 2.7.8.
A rather large group of enzymes comprising not only those transferring phosphate but also diphosphate, nucleotidyl residues, and others. These have also been subdivided according to the acceptor group. (From Enzyme Nomenclature, 1992) EC 2.7.
The ester of diacylglycerol with the terminal phosphate of cytidine diphosphate. It serves as an intermediate in the biosynthesis of phosphatidylethanolamine and phosphatidylserine in bacteria.
An enzyme that catalyzes the formation of phosphatidylserine and CMP from CDPdiglyceride plus serine. EC 2.7.8.8.
A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
A syndrome inherited as an autosomal recessive trait and incompatible with life. The main features are narrow thorax, short ribs, scapular and pelvic dysplasia, and polydactyly.
A genus of coccoid bacteria in the family PLANOCOCCACEAE. They are widely distributed in various habitats including sea water, freshwater ponds, cyanobacterial mats, and in marine animals.
A publication issued at stated, more or less regular, intervals.
A quantitative measure of the frequency on average with which articles in a journal have been cited in a given period of time.
"The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.
The branch of science concerned with the interrelationship of organisms and their ENVIRONMENT, especially as manifested by natural cycles and rhythms, community development and structure, interactions between different kinds of organisms, geographic distributions, and population alterations. (Webster's, 3d ed)
The use of statistical methods in the analysis of a body of literature to reveal the historical development of subject fields and patterns of authorship, publication, and use. Formerly called statistical bibliography. (from The ALA Glossary of Library and Information Science, 1983)
Sequential operating programs and data which instruct the functioning of a digital computer.
A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.
The portion of an interactive computer program that issues messages to and receives commands from a user.
The process of pictorial communication, between human and computers, in which the computer input and output have the form of charts, drawings, or other appropriate pictorial representation.
A field of biology concerned with the development of techniques for the collection and manipulation of biological data, and the use of such data to make biological discoveries or predictions. This field encompasses all computational methods and theories for solving biological problems including manipulation of models and datasets.
A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.
Specific languages used to prepare computer programs.
The determination of the pattern of genes expressed at the level of GENETIC TRANSCRIPTION, under specific circumstances or in a specific cell.
Hybridization of a nucleic acid sample to a very large set of OLIGONUCLEOTIDE PROBES, which have been attached individually in columns and rows to a solid support, to determine a BASE SEQUENCE, or to detect variations in a gene sequence, GENE EXPRESSION, or for GENE MAPPING.
Annual cereal grass of the family POACEAE and its edible starchy grain, rice, which is the staple food of roughly one-half of the world's population.
The encapsulated embryos of flowering plants. They are used as is or for animal feed because of the high content of concentrated nutrients like starches, proteins, and fats. Rapeseed, cottonseed, and sunflower seed are also produced for the oils (fats) they yield.
Seeds from grasses (POACEAE) which are important in the diet.
Mathematical procedure that transforms a number of possibly correlated variables into a smaller number of uncorrelated variables called principal components.
Derivatives of phosphatidic acids in which the phosphoric acid is bound in ester linkage to the hexahydroxy alcohol, myo-inositol. Complete hydrolysis yields 1 mole of glycerol, phosphoric acid, myo-inositol, and 2 moles of fatty acids.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
A cell surface receptor involved in regulation of cell growth and differentiation. It is specific for EPIDERMAL GROWTH FACTOR and EGF-related peptides including TRANSFORMING GROWTH FACTOR ALPHA; AMPHIREGULIN; and HEPARIN-BINDING EGF-LIKE GROWTH FACTOR. The binding of ligand to the receptor causes activation of its intrinsic tyrosine kinase activity and rapid internalization of the receptor-ligand complex into the cell.
Phosphotransferases that catalyzes the conversion of 1-phosphatidylinositol to 1-phosphatidylinositol 3-phosphate. Many members of this enzyme class are involved in RECEPTOR MEDIATED SIGNAL TRANSDUCTION and regulation of vesicular transport with the cell. Phosphatidylinositol 3-Kinases have been classified both according to their substrate specificity and their mode of action within the cell.
Biochemical identification of mutational changes in a nucleotide sequence.
A cell surface protein-tyrosine kinase receptor that is overexpressed in a variety of ADENOCARCINOMAS. It has extensive homology to and heterodimerizes with the EGF RECEPTOR, the ERBB-3 RECEPTOR, and the ERBB-4 RECEPTOR. Activation of the erbB-2 receptor occurs through heterodimer formation with a ligand-bound erbB receptor family member.
The walnut plant family of the order Juglandales, subclass Hamamelidae, class Magnoliopsida. They are mainly temperate zone trees.
Copies of a work or document distributed to the public by sale, rental, lease, or lending. (From ALA Glossary of Library and Information Science, 1983, p181)
Critical and exhaustive investigation or experimentation, having for its aim the discovery of new facts and their correct interpretation, the revision of accepted conclusions, theories, or laws in the light of newly discovered facts, or the practical application of such new or revised conclusions, theories, or laws. (Webster, 3d ed)
An aberration in which a chromosomal segment is deleted and reinserted in the same place but turned 180 degrees from its original orientation, so that the gene sequence for the segment is reversed with respect to that of the rest of the chromosome.
Recurrent clonic contraction of facial muscles, restricted to one side. It may occur as a manifestation of compressive lesions involving the seventh cranial nerve (FACIAL NERVE DISEASES), during recovery from BELL PALSY, or in association with other disorders. (From Adams et al., Principles of Neurology, 6th ed, p1378)
Research that involves the application of the natural sciences, especially biology and physiology, to medicine.
A species of gram-negative, anaerobic, rod-shaped bacteria isolated from soil, animal intestines and feces, and fresh and salt water.
A genus of gram-negative, anaerobic, rod-shaped bacteria capable of reducing sulfur compounds to hydrogen sulfide. Organisms are isolated from anaerobic mud of fresh and salt water, animal intestines, manure, and feces.
Family of gram-positive, facultatively anaerobic bacteria, in the order Bacillales. Genera include Gemella, Macrococcus, Salinicoccus, and STAPHYLOCOCCUS.
Commonly observed structural components of proteins formed by simple combinations of adjacent secondary structures. A commonly observed structure may be composed of a CONSERVED SEQUENCE which can be represented by a CONSENSUS SEQUENCE.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
The dynamic collection of metabolites which represent a cell's or organism's net metabolic response to current conditions.
The systematic identification and quantitation of all the metabolic products of a cell, tissue, organ, or organism under varying conditions. The METABOLOME of a cell or organism is a dynamic collection of metabolites which represent its net response to current conditions.
The largest country in North America, comprising 10 provinces and three territories. Its capital is Ottawa.
A pyridoxal-phosphate protein that catalyzes the deamination of THREONINE to 2-ketobutyrate and AMMONIA. The role of this enzyme can be biosynthetic or biodegradative. In the former role it supplies 2-ketobutyrate required for ISOLEUCINE biosynthesis, while in the latter it is only involved in the breakdown of threonine to supply energy. This enzyme was formerly listed as EC 4.2.1.16.
An essential amino acid occurring naturally in the L-form, which is the active form. It is found in eggs, milk, gelatin, and other proteins.
A province of Canada on the Pacific coast. Its capital is Victoria. The name given in 1858 derives from the Columbia River which was named by the American captain Robert Gray for his ship Columbia which in turn was named for Columbus. (From Webster's New Geographical Dictionary, 1988, p178 & Room, Brewer's Dictionary of Names, 1992, p81-2)
The systematic study of the complete DNA sequences (GENOME) of organisms.

Cloning and expression of a wheat (Triticum aestivum L.) phosphatidylserine synthase cDNA. Overexpression in plants alters the composition of phospholipids. (1/102)

We describe the cloning of a wheat cDNA (TaPSS1) that encodes a phosphatidylserine synthase (PSS) and provides the first strong evidence for the existence of this enzyme in a higher eukaryotic cell. The cDNA was isolated on its ability to confer increased resistance to aluminum toxicity when expressed in yeast. The sequence of the predicted protein encoded by TaPSS1 shows homology to PSS from both yeast and bacteria but is distinct from the animal PSS enzymes that catalyze base-exchange reactions. In wheat, Southern blot analysis identified the presence of a small family of genes that cross-hybridized to TaPSS1, and Northern blots showed that aluminum induced TaPSS1 expression in root apices. Expression of TaPSS1 complemented the yeast cho1 mutant that lacks PSS activity and altered the phospholipid composition of wild type yeast, with the most marked effect being increased abundance of phosphatidylserine (PS). Arabidopsis thaliana leaves overexpressing TaPSS1 showed a marked enhancement in PSS activity, which was associated with increased biosynthesis of PS at the expense of both phosphatidylinositol and phosphatidylglycerol. Unlike mammalian cells where PS accumulation is tightly regulated even when the capacity for PS biosynthesis is increased, plant cells accumulated large amounts of PS when TaPSS1 was overexpressed. High levels of TaPSS1 expression in Arabidopsis and tobacco (Nicotiana tabacum) led to the appearance of necrotic lesions on leaves, which may have resulted from the excessive accumulation of PS. The cloning of TaPSS1 now provides evidence that the yeast pathway for PS synthesis exists in some plant tissues and provides a tool for understanding the pathways of phospholipid biosynthesis and their regulation in plants.  (+info)

Reconstituted phosphatidylserine synthase from Escherichia coli is activated by anionic phospholipids and micelle-forming amphiphiles. (2/102)

The activity of phosphatidylserine (PS) synthase (CDP-1, 2-diacyl-sn-glycerol: l-serine O-phosphatidyltransferase, EC 2.7.8. 8) from Escherichia coli was studied after reconstitution with lipid vesicles of various compositions. PS synthase exhibited practically no activity in the absence of a detergent and with the substrate CDP-diacylglycerol (CDP-DAG) present only in the lipid vesicles. Inclusion of octylglucoside (OG) in the assay mixture increased the activity 20- to 1000-fold, the degree of activation depending on the lipid composition of the vesicles. Inclusion of additional CDP-DAG in the assay mixture increased the activity 5- to 25-fold. When the fraction of phosphatidylglycerol (PG) was increased from 15 to 100 mol% in the vesicles the activity increased 10-fold using the assay mixture containing OG. The highest activities were exhibited with the anionic lipids synthesized by E. coli, namely PG, diphosphatidylglycerol (DPG), and phosphatidic acid, while phosphatidylinositol gave a lower activity. Cryotransmission electron microscopy showed that transformation of the vesicles to micelles brings about an activation of the enzyme that is proportional to the degree of micellization. Thus, the activity of PS synthase is modulated by the lipid aggregate structure and by the fraction and type of anionic phospholipid in the aggregates. The increase in the activity caused by PG and DPG is physiologically relevant; it may be part of a regulatory mechanism that keeps the balance between phosphatidylethanolamine, and the sum of PG and DPG, nearly constant in wild-type E. coli cells.  (+info)

Isolation of a Chinese hamster ovary cell mutant defective in intramitochondrial transport of phosphatidylserine. (3/102)

A CHO-K1 cell mutant with a specific decrease in cellular phosphatidylethanolamine (PE) level was isolated as a variant resistant to Ro09-0198, a PE-directed antibiotic peptide. The mutant was defective in the phosphatidylserine (PS) decarboxylation pathway for PE formation, in which PS produced in the endoplasmic reticulum is transported to mitochondria and then decarboxylated by an inner mitochondrial membrane enzyme, PS decarboxylase. Neither PS formation nor PS decarboxylase activity was reduced in the mutant, implying that the mutant is defective in some step of PS transport. The transport processes of phospholipids between the outer and inner mitochondrial membrane were analyzed by use of isolated mitochondria and two fluorescence-labeled phospholipid analogs, 1-palmitoyl-2-[N-[6(7-nitrobenz-2-oxa-1, 3-diazol-4-yl)amino]caproyl]-PS (C6-NBD-PS) and C6-NBD-phosphatidylcholine (C6-NBD-PC). On incubation with the CHO-K1 mitochondria, C6-NBD-PS was readily decarboxylated to C6-NBD-PE, suggesting that the PS analog was partitioned into the outer leaflet of mitochondria and then translocated to the inner mitochondrial membrane. The rate of decarboxylation of C6-NBD-PS in the mutant mitochondria was reduced to approximately 40% of that in the CHO-K1 mitochondria. The quantity of phospholipid analogs translocated from the outer leaflet of mitochondria into inner mitochondrial membranes was further examined by selective extraction of the analogs from the outer leaflet of mitochondria. In the mutant mitochondria, the translocation of C6-NBD-PS was significantly reduced, whereas the translocation of C6-NBD-PC was not affected. These results indicate that the mutant is defective in PS transport between the outer and inner mitochondrial membrane and provide genetic evidence for the existence of a specific mechanism for intramitochondrial transport of PS.  (+info)

One of the origins of plasma membrane phosphatidylserine in plant cells is a local synthesis by a serine exchange activity. (4/102)

In plant cells, as in animal cells, the endoplasmic reticulum (ER) is considered to be the major site of phospholipid synthesis, and it has been shown that phosphatidylserine (PS) reaches the plasma membrane via the vesicular ER-Golgi-plasma membrane pathway in leek cells. However, it has never been determined whether the plasma membrane of leek cells is able to synthesize PS. We have analyzed the distribution of PS synthesizing enzymes along the vesicular pathway. In ER, Golgi and plasma membrane fractions isolated from leek cells, we have measured the activity of the two biosynthetic pathways leading to the synthesis of PS, i.e. serine exchange and CTP cytidylyltransferase plus PS synthase. We have found a high serine exchange activity in the plasma membrane fraction, and then determined that this membrane is able to synthesize both long chain fatty acid- and very long chain fatty acid-containing PS. Therefore, the PS in the plasma membrane of leek cells has two different origins: the intracellular vesicular pathway from the ER and a local synthesis in the plasma membrane.  (+info)

Interaction of phosphatidylserine synthase from E. coli with lipid bilayers: coupled plasmon-waveguide resonance spectroscopy studies. (5/102)

The interaction of phosphatidylserine (PS) synthase from Escherichia coli with lipid membranes was studied with a recently developed variant of the surface plasmon resonance technique, referred to as coupled plasmon-waveguide resonance spectroscopy. The features of the new technique are increased sensitivity and spectral resolution, and a unique ability to directly measure the structural anisotropy of lipid and proteolipid films. Solid-supported lipid bilayers with the following compositions were used: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC); POPC-1-palmitoyl-2-oleoyl-sn-glycero-3-phosphate (POPA) (80:20, mol/mol); POPC-POPA (60:40, mol/mol); and POPC-1-palmitoyl-2-oleoyl-sn-glycero-3-[phospho-rac-(1-glycerol)] (POPG) (75:25, mol/mol). Addition of either POPA or POPG to a POPC bilayer causes a considerable increase of both the bilayer thickness and its optical anisotropy. PS synthase exhibits a biphasic interaction with the bilayers. The first phase, occurring at low protein concentrations, involves both electrostatic and hydrophobic interactions, although it is dominated by the latter, and the enzyme causes a local decrease of the ordering of the lipid molecules. The second phase, occurring at high protein concentrations, is predominantly controlled by electrostatic interactions, and results in a cooperative binding of the enzyme to the membrane surface. Addition of the anionic lipids to a POPC bilayer causes a 5- to 15-fold decrease in the protein concentration at which the first binding phase occurs. The results reported herein lend experimental support to a previously suggested mechanism for the regulation of the polar head group composition in E. coli membranes.  (+info)

Regulation of the DPP1-encoded diacylglycerol pyrophosphate (DGPP) phosphatase by inositol and growth phase. Inhibition of DGPP phosphatase activity by CDP-diacylglyceron and activation of phosphatidylserine synthase activity by DGPP. (6/102)

The regulation of the Saccharomyces cerevisiae DPP1-encoded diacylglycerol pyrophosphate (DGPP) phosphatase by inositol supplementation and growth phase was examined. Addition of inositol to the growth medium resulted in a dose-dependent increase in the level of DGPP phosphatase activity in both exponential and stationary phase cells. Activity was greater in stationary phase cells when compared with exponential phase cells, and the inositol- and growth phase-dependent regulations of DGPP phosphatase were additive. Analyses of DGPP phosphatase mRNA and protein levels, and expression of beta-galactosidase activity driven by a P(DPP1)-lacZ reporter gene, indicated that a transcriptional mechanism was responsible for this regulation. Regulation of DGPP phosphatase by inositol and growth phase occurred in a manner that was opposite that of many phospholipid biosynthetic enzymes. Regulation of DGPP phosphatase expression by inositol supplementation, but not growth phase, was altered in opi1Delta, ino2Delta, and ino4Delta phospholipid synthesis regulatory mutants. CDP-diacylglycerol, a phospholipid pathway intermediate used for the synthesis of phosphatidylserine and phosphatidylinositol, inhibited DGPP phosphatase activity by a mixed mechanism that caused an increase in K(m) and a decrease in V(max). DGPP stimulated the activity of pure phosphatidylserine synthase by a mechanism that increased the affinity of the enzyme for its substrate CDP-diacylglycerol. Phospholipid composition analysis of a dpp1Delta mutant showed that DGPP phosphatase played a role in the regulation of phospholipid metabolism by inositol, as well as regulating the cellular levels of phosphatidylinositol.  (+info)

Cloning and characterization of the phosphatidylserine synthase gene of Agrobacterium sp. strain ATCC 31749 and effect of its inactivation on production of high-molecular-mass (1-->3)-beta-D-glucan (curdlan). (7/102)

Genes involved in the production of the extracellular (1-->3)-beta-glucan, curdlan, by Agrobacterium sp. strain ATCC 31749 were described previously (Stasinopoulos et al., Glycobiology 9:31-41, 1999). To identify additional curdlan-related genes whose protein products occur in the cell envelope, the transposon TnphoA was used as a specific genetic probe. One mutant was unable to produce high-molecular-mass curdlan when a previously uncharacterized gene, pss(AG), encoding a 30-kDa, membrane-associated phosphatidylserine synthase was disrupted. The membranes of the mutant lacked phosphatidylethanolamine (PE), whereas the phosphatidylcholine (PC) content was unchanged and that of both phosphatidylglycerol and cardiolipin was increased. In the mutant, the continued appearance of PC revealed that its production by this Agrobacterium strain is not solely dependent on PE in a pathway controlled by the Pss(AG) protein at its first step. Moreover, PC can be produced in a medium lacking choline. When the pss(AG)::TnphoA mutation was complemented by the intact pss(AG) gene, both the curdlan deficiency and the phospholipid profile were restored to wild-type, demonstrating a functional relationship between these two characteristics. The effect of the changed phospholipid profile could occur through an alteration in the overall charge distribution on the membrane or a specific requirement for PE for the folding into or maintenance of an active conformation of any or all of the structural proteins involved in curdlan production or transport.  (+info)

CDP-2,3-Di-O-geranylgeranyl-sn-glycerol:L-serine O-archaetidyltransferase (archaetidylserine synthase) in the methanogenic archaeon Methanothermobacter thermautotrophicus. (8/102)

CDP-2,3-di-O-geranylgeranyl-sn-glycerol:L-serine O-archaetidyltransferase (archaetidylserine synthase) activity in cell extracts of Methanothermobacter thermautotrophicus cells was characterized. The enzyme catalyzed the formation of unsaturated archaetidylserine from CDP-unsaturated archaeol and L-serine. The identity of the reaction products was confirmed by thin-layer chromatography, fast atom bombardment-mass spectrum analysis, and chemical degradation. The enzyme showed maximal activity in the presence of 10 mM Mn2+ and 1% Triton X-100. Among various synthetic substrate analogs, both enantiomers of CDP-unsaturated archaeols with ether-linked geranylgeranyl chains and CDP-saturated archaeol with ether-linked phytanyl chains were similarly active toward the archaetidylserine synthase. The activity on the ester analog of the substrate was two to three times higher than that on the corresponding ether-type substrate. The activity of D-serine with the enzyme was 30% of that observed for L-serine. A trace amount of an acid-labile, unsaturated archaetidylserine intermediate was detected in the cells by a pulse-labeling experiment. A gene (MT1027) in M. thermautotrophicus genome annotated as the gene encoding phosphatidylserine synthase was found to be homologous to Bacillus subtilis pssA but not to Escherichia coli pssA. The substrate specificity of phosphatidylserine synthase from B. subtilis was quite similar to that observed for the M. thermautotrophicus archaetidylserine synthase, while the E. coli enzyme had a strong preference for CDP-1,2-diacyl-sn-glycerol. It was concluded that M. thermautotrophicus archaetidylserine synthase belongs to subclass II phosphatidylserine synthase (B. subtilis type) on the basis of not only homology but also substrate specificity and some enzymatic properties. The possibility that a gene encoding the subclass II phosphatidylserine synthase might be transferred from a bacterium to an ancestor of methanogens is discussed.  (+info)

Accepted name: phosphatidylcholine synthase. Reaction: CDP-diacylglycerol + choline = CMP + phosphatidylcholine. Other name(s): CDP-diglyceride-choline O-phosphatidyltransferase. Systematic name: CDP-diacylglycerol:choline O-phosphatidyltransferase. Comments: Requires divalent cations, with Mn2+ being more effective than Mg2+.. Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 243666-86-6. References: 1. de Rudder, K.E.E., Sohlenkamp, C. and Geiger, O. Plant-exudated choline is used for rhizobial membrane lipid biosynthesis by phosphatidylcholine synthase. J. Biol. Chem. 274 (1999) 20011-20016. [PMID: 10391951]. 2. Sohlenkamp, C., de Rudder, K.E.E., Röhrs, V., López-Lara, I.M. and Geiger, O. Cloning and characterization of the gene for phosphatidylcholine synthase. J. Biol. Chem. 275 (2000) 18919-18925. [PMID: 10858449]. ...
Golden Horizon Biologics is phosphatidylserine manufacture. This page describes the introduction of phosphatidylserine, phosphatidylserine benefits and phosphatidylserine use
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Several weak hits in gapped BLAST to PSGA sequences, e.g. residues 75-210 are 36% similar to PGSA_MYCPN. All similarities begin at around residue 75 of UU364. MG114, CT797, TP0256 and CT496 are predicted phosphatidylglycerophosphate synthases with similarities to UU364 beginning around residue 17 ...
What is Phosphatidylserine? Phosphatidylserine is found in high amounts in the brain where it helps support a multitude of neurotransmitter systems including acetylcholine, serotonin, norepinephrine, and dopamine.
What is Phosphatidylserine? Phosphatidylserine is found in high amounts in the brain where it helps support a multitude of neurotransmitter systems including acetylcholine, serotonin, norepinephrine, and dopamine.
In medicine, phosphatidylserine is used to support the treatment of dementia and hyperactivity. The use of phosphatidylserine is intended to improve the
Phosphatidylserine is a phospholipid that is a component of cell membranes in your body. Its been associated with a number of benefits, from...
Phosphatidylserine supplies a supplemental source of this important phospholipid, which is a structural part of biological membranes. Available at druglessdoctor.com.
Find patient medical information for PHOSPHATIDYLSERINE on WebMD including its uses, effectiveness, side effects and safety, interactions, user ratings and products that have it.
Cant afford them both so which would be more desirable for keeping cortisol levels lower. Having great results with Phosphatidylserine 800 to 1000mgs
PG(15:1(9Z)/18:0) is a phosphatidylglycerol. Phosphatidylglycerols consist of a glycerol 3-phosphate backbone esterified to either saturated or unsaturated fatty acids on carbons 1 and 2. As is the case with diacylglycerols, phosphatidylglycerols can have many different combinations of fatty acids of varying lengths and saturation attached to the C-1 and C-2 positions. PG(15:1(9Z)/18:0), in particular, consists of one 9Z-pentadecenoyl chain to the C-1 atom, and one octadecanoyl to the C-2 atom. In E. coli glycerophospholipid metabolism, phosphatidylglycerol is formed from phosphatidic acid (1,2-diacyl-sn-glycerol 3-phosphate) by a sequence of enzymatic reactions that proceeds via two intermediates, cytidine diphosphate diacylglycerol (CDP-diacylglycerol) and phosphatidylglycerophosphate (PGP, a phosphorylated phosphatidylglycerol). Phosphatidylglycerols, along with CDP-diacylglycerol, also serve as precursor molecules for the synthesis of cardiolipin, a phospholipid found in membranes ...
PG(16:0/18:0) is a phosphatidylglycerol. Phosphatidylglycerols consist of a glycerol 3-phosphate backbone esterified to either saturated or unsaturated fatty acids on carbons 1 and 2. As is the case with diacylglycerols, phosphatidylglycerols can have many different combinations of fatty acids of varying lengths and saturation attached to the C-1 and C-2 positions. PG(16:0/18:0), in particular, consists of one hexadecanoyl chain to the C-1 atom, and one octadecanoyl to the C-2 atom. In E. coli glycerophospholipid metabolism, phosphatidylglycerol is formed from phosphatidic acid (1,2-diacyl-sn-glycerol 3-phosphate) by a sequence of enzymatic reactions that proceeds via two intermediates, cytidine diphosphate diacylglycerol (CDP-diacylglycerol) and phosphatidylglycerophosphate (PGP, a phosphorylated phosphatidylglycerol). Phosphatidylglycerols, along with CDP-diacylglycerol, also serve as precursor molecules for the synthesis of cardiolipin, a phospholipid found in membranes ...
PhosphatidylSerine iis a phospholipid that helps focus, memory, learning, coordination and brain. It is the highest quality soy-free, non-GMO phosphatidylserine, Sharp-PS® GREEN.
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CDP-Diacylglycerol-Inositol 3-Phosphatidyltransferase: An enzyme that catalyzes the formation of PHOSPHATIDYLINOSITOL and CMP from CDP-DIACYLGLYCEROL and MYOINOSITOL.
CDIPT (CDP-diacylglycerol--inositol 3-phosphatidyltransferase), Authors: Dessen P. Published in: Atlas Genet Cytogenet Oncol Haematol.
PS 100 (standardized phosphatidylserine) Supports mental function Phosphatidylserine is a phospholipid found in all cells, but is most concentrated in brain cells. This familiarly-called brain nutrient supports cognitive function, emotional well-being and behavioral performance by restoring cell membrane composition. It has also been shown to support memory. In a double blind placebo controlled multicenter study of 425 individuals, daily supplementation of phosphatidylserine over six months resulted in statistically significant support of behavioral and cognitive parameters. In another six-month study of 40 individuals, phosphatidylserine supplementation enhanced cerebral metabolism and outcomes of cognitive training. These findings are consistent with earlier studies. In a placebo- controlled investigation of 149 subjects, the group receiving phosphatidylserine scored higher than placebo in performance tests related to memory tasks of daily life. In a trial of 35 subjects, those receiving
This gene encodes a member of de famiwy of adenywyw cycwases, which are membrane-associated enzymes dat catawyze de formation of de secondary messenger cycwic adenosine monophosphate (cAMP) from ATP. ADCY2 has awso been found to accewerate phosphor-acidification, awong wif gwycogen syndesis and breakdown, uh-hah-hah-hah.[9] This enzyme is insensitive to Ca2+/cawmoduwin, and is stimuwated by de G protein beta and gamma subunit compwex.[6] Therefore, ADCY2 is highwy reguwated by G-proteins, cawcium, cawmoduwin, pyrophosphate, and post-transwationaw modifications. Recentwy, it has been discover dat ADCY2 can activated by a Raf kinase-mediated serine phosphorywation, uh-hah-hah-hah.[10] In aggregate, Raf kinase associates wif adenywyw cycwases and is isoform-sewective, which incwudes adenywyw cycwase type 2. In human embryonic kidney cewws, ADCY2 is stimuwated by activation of Gq-coupwed muscarinic receptors drough protein kinase C (PKC) to generate wocawized cAMP. Once de agonist binding to de ...
MetabolismFatty acid and phospholipid metabolismBiosynthesisfatty acid/phospholipid synthesis protein PlsX (TIGR00182; HMM-score: 408.3) ...
Fingerprint Dive into the research topics of Effect of membrane phospholipid composition changes on adenylate cyclase activity in normal and rous-sarcoma-transformed chicken embryo fibroblasts. Together they form a unique fingerprint. ...
In the presence of the drug, the incorporation of cytidine, but not of inorganic phosphate, into phosphatidyl-CMP (CDP-diacylglycerol) was dependent on the cytidine concentration ...
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There are many benefits derived from maintaining good levels of Phosphatidylserine from age-related decline in mental function, improving thinking skills, enhancing mood, and other benefits.
TY - JOUR. T1 - Cytostatic effect of inostamycin, an inhibitor of cytidine 5′-diphosphate 1,2-diacyl-sn-glycerol (CDP-DG). T2 - Inositol transferase, on oral squamous cell carcinoma cell lines. AU - Baba, Yuh. AU - Tsukuda, Mamoru. AU - Mochimatsu, Izumi. AU - Furukawa, Shigeru. AU - Kagata, Hiroko. AU - Nagashima, Yoji. AU - Koshika, Shinri. AU - Imoto, Masaya. AU - Kato, Yasumasa. N1 - Funding Information: We thank Dr E. W. Thompson (St Vincents Institute of Medical Research, Fitzroy, Australia) for preparation of the manuscript. A part of this study was supported by a Grant-in-Aid from the Ministry of Education, Culture, Sports, and Science of Japan.. PY - 2001. Y1 - 2001. N2 - Inostamycin, which was recently isolated from Streptomyces sp. MH816-AF15 as an inhibitor of cytidine 5′-diphosphate 1,2-diacyl-sn-glycerol (CDP-DG): inositol transferase, caused a G1-phase accumulation in the cell cycle of small cell lung carcinomas. To investigate whether the cytostatic effect of inostamycin is ...
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, ...
p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.,/p> ,p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.,/p> ,p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).,/p> ,p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x,sup>64,/sup> + x,sup>4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class=publication>Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.,br /> ,strong>Cyclic redundancy and other checksums,/strong>,br /> ,a href=http://www.nrbook.com/b/bookcpdf.php>Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993),/a>),/p> Checksum:i ...
Gene Information This gene encodes a member of the family of adenylate cyclases which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4 along with adenylate cyclases 2 and 3 is expressed in olfactory cilia suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. Alternative splicing results in transcript variants. [provided by RefSeq Nov 2010]. ...
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010 ...
Low prices on Phosphatidylserine! Phosphatidylserine supports memory, focus and athletic performance*. Phosphatidylserine (PS) is a phospholipid (a fat containing phosphorus) found in every cell membrane in our bodies. It has many functions, but most important is its role in brain health. Clinical studies have shown PS to support brain glucose metabolism.
BoostCeuticals is currently manufacturing a good quality supplement which actually contains Phosphatidyl serine 100 mg daily dose. This type of dosage is popular and effective but can it be even better. Combining this Phosphatidylserine dosage with other important complimentary ingredients makes it a true Phosphatidylserine complex. It is also well documented how it works so much better with DMAE and this is included all in one supplement ...
BeWellBuzz) Phosphatidylserine belongs to a class of chemicals known as phospholipids, which are fat-soluble chemicals that are vital for cell membranes.Phosphatidylserine is a non-essential nutrient. The term non-essential nutrient refers to nutrients that our body can produce naturally. We can also procure Phosphatidylserine from food. With that said, it is important ... Continue Reading ...
BeWellBuzz) Phosphatidylserine belongs to a class of chemicals known as phospholipids, which are fat-soluble chemicals that are vital for cell membranes.Phosphatidylserine is a non-essential nutrient. The term non-essential nutrient refers to nutrients that our body can produce naturally. We can also procure Phosphatidylserine from food. With that said, it is important ... Continue Reading ...
Buy PHOSPHATIDYL SERINE Online.Phosphatidylserine consists of phosphatidylserine which is a phospholipid of vital importance for the good working order of the brain. On the other hand, Phosphatidylserine increa
Thank you for your interest in spreading the word about Biochemical Society Transactions.. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.. ...
During the sporulation process of ,I,Saccharomyces cerevisiae,/I,, meiotic progression is accompanied by ,I,de novo,/I, formation of the prospore membrane inside the cell. However, it remains to be determined whether certain species of lipids are required for spore formation in yeast. In this study, we analyzed the requirement of the synthesis of phosphatidylethanolamine (PE), phosphatidylcholine (PC), and ergosterol for spore formation using strains in which the synthesis of these lipids can be controlled. When synthesis of PE and PC was repressed, sporulation efficiency decreased. This suggests that synthesis of these phospholipids is vital to proper sporulation. In addition, sporulation was also impaired in cells with a lowered sterol content, raising the possibility that sterol content is also important for spore formation.. ...
Clostridium butyricum phosphatidyltransferase: from Clostridium butyricum; catalyzes transfer of the phosphatidyl moiety of phosphatidylethanolamine, phosphatidylglycerol or phosphatidylserine to primary alcohols such as glycerol, serine and ethanolamine; catalyze transfer of both the diacyl and alkenyl acyl forms of glycerophospholipids, but the diacyl forms are used preferentially
JOSÉ F. W. SPRÍCIGO, UNB; MATEUS N. DIÓGENES, UNB; LIGIANE O. LEME, UNB; ANA L. GUIMARÃES, UNB; CAROLLE V. MUTERLLE, UNB; BIANCA DAMIANI MARQUES SILVA, CENARGEN; DAVID SOLÀ-ORIOL, UNIVERSITAT AUTÒNOMA DE BARCELONA, SPAIN; IVO PIVATO, UNB; LUCIANO PAULINO DA SILVA, CENARGEN; MARGOT ALVES NUNES DODE, CENARGEN ...
Toxoplasma gondii is among the most prevalent protozoan parasites, which infects a wide range of organisms including one-third of the human population. Its rapid intracellular replication within a vacuole requires efficient synthesis of glycerophospholipids. Cytidine diphosphate-diacylglycerol (CDP-DAG) serves as a major precursor for phospholipid synthesis. Given the peculiarities of lipid biogenesis, understanding the mechanism and physiological importance of CDP-DAG synthesis is particularly relevant in T. gondii Here, we report the occurrence of two phylogenetically divergent CDP-DAG synthase (CDS) enzymes in the parasite. The eukaryotic-type TgCDS1 and the prokaryotic-type TgCDS2 reside in the endoplasmic reticulum (ER) and apicoplast, respectively. Conditional knockdown of TgCDS1 severely attenuated the parasite growth and resulted in a nearly complete loss of virulence in a mouse model. Moreover, mice infected with the TgCDS1 mutant became fully resistant to challenge infection with a ...
The FHIR Implementation Guide provides a set of profiles for detection, validation, reporting, and ultimately recording/persisting Adverse Events associated with blood transfusions and vaccinations. There are two sets of profiles with the first set intended to enable the detection, validation, and recording of conditions and observations on a patients record that would indicate the occurrence of an Adverse Event. The second set of profiles provides mappings to the ICH Individual Care Study Report (ICSR) specifications, specifically FDAs FAERS (FDA Adverse Event Reporting System) and VAERS (Vaccine Adverse Event Reporting System) implementations of those specifications, for the purposes of allowing the submission of Adverse Event Case Reports to FDA using the FHIR profiles after they have been transformed into the current XML specifications ...
Purified Phosphatidylserine Apoptosis Kit (Green Fluorescence 405) from Creative Biomart. Phosphatidylserine Apoptosis Kit (Green Fluorescence 405) can be used for research.
... serine ethanolaminephosphotransferase EC 2.7.8.5: CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase EC 2.7.8.6 ... CDP-diacylglycerol-serine O-phosphatidyltransferase EC 2.7.8.9: phosphomannan mannosephosphotransferase EC 2.7.8.10: ... CDP-diacylglycerol-choline O-phosphatidyltransferase EC 2.7.8.25: triphosphoribosyl-dephospho-CoA synthase EC 2.7.8.26: ... L-serine-phosphatidylethanolamine phosphatidyltransferase EC 2.7.8.30: undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose ...
CDP-diacylglycerol-inositol 3-phosphatidyltransferase MeSH D08.811.913.696.900.150 - CDP-diacylglycerol-serine O- ... Serine-type D-Ala-D-Ala carboxypeptidase MeSH D08.811.277.656.350.245.280 - gamma-glutamyl hydrolase MeSH D08.811.277.656. ... serine-trna ligase MeSH D08.811.464.263.200.800 - threonine-tRNA ligase MeSH D08.811.464.263.200.850 - tryptophan-tRNA ligase ... protein-serine-threonine kinases MeSH D08.811.913.696.620.682.700.062 - activin receptors MeSH D08.811.913.696.620.682.700.062. ...
L-serine, O-phosphatidyltransferase, and CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase. This enzyme participates in ... L-serine O-phosphatidyltransferase, phosphatidylserine synthetase, CDP-diacylglycerol-L-serine O-phosphatidyltransferase, ... a CDP-diacylglycerol-serine O-phosphatidyltransferase (EC 2.7.8.8) is an enzyme that catalyzes the chemical reaction CDP- ... CDP-diglyceride-L-serine phosphatidyltransferase, CDP-diglyceride:serine phosphatidyltransferase, cytidine 5'-diphospho-1,2- ...
CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase. *CDP-diacylglycerol-serine O-phosphatidyltransferase. *CDP- ... protein serine/threonine kinase activity. • GO:0001948 protein binding. • insulin receptor substrate binding. • ATP binding. • ... positive regulation of peptidyl-serine phosphorylation. • platelet activation. • Fc-epsilon receptor signaling pathway. • ...
CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase. *CDP-diacylglycerol-serine O-phosphatidyltransferase. *CDP- ...
CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase. *CDP-diacylglycerol-serine O-phosphatidyltransferase. *CDP- ...
CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase. *CDP-diacylglycerol-serine O-phosphatidyltransferase. *CDP- ...
CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase. *CDP-diacylglycerol-serine O-phosphatidyltransferase. *CDP- ...
CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase. *CDP-diacylglycerol-serine O-phosphatidyltransferase. *CDP- ...
CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase. *CDP-diacylglycerol-serine O-phosphatidyltransferase. *CDP- ... Phosphorylation occurs at two sites within the heptapeptide repeat, at Serine 5 and Serine 2. Serine 5 phosphorylation is ... It has a kinase activity that phosphorylates the C-terminal domain (CTD) of Pol II at the amino acid serine. This switches the ... The CTD consists of repetitions of an amino acid motif, YSPTSPS, of which Serines and Threonines can be phosphorylated. The ...
CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase. *CDP-diacylglycerol-serine O-phosphatidyltransferase. *CDP- ... A serine/threonine protein kinase (EC 2.7.11.1) is a kinase enzyme that phosphorylates the OH group of serine or threonine ( ... Serine/threonine-specific protein kinase. From Wikipedia, the free encyclopedia. (Redirected from Non-specific serine/threonine ... While serine/threonine kinases all phosphorylate serine or threonine residues in their substrates, they select specific ...
CDIPT: CDP-diacylglycerol-inositol 3-phosphatidyltransferase. *CFDP1: Craniofacial development protein 1. *CHDS1: Coronary ... TAO2: encoding Serine/threonine-protein kinase TAO2. *TBC1D24: encoding protein TBC1 domain family, member 24 ...
L-serine, O-phosphatidyltransferase, and CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase. This enzyme participates in ... L-serine O-phosphatidyltransferase, phosphatidylserine synthetase, CDP-diacylglycerol-L-serine O-phosphatidyltransferase, ... a CDP-diacylglycerol-serine O-phosphatidyltransferase (EC 2.7.8.8) is an enzyme that catalyzes the chemical reaction CDP- ... CDP-diglyceride-L-serine phosphatidyltransferase, CDP-diglyceride:serine phosphatidyltransferase, cytidine 5-diphospho-1,2- ...
CDP-diacylglycerol--serine O-phosphatidyltransferase (EC:2.7.8.8*Search proteins in UniProtKB for this EC number. ... sp,Q9ZBM2,PSS_MYCLE CDP-diacylglycerol--serine O-phosphatidyltransferase OS=Mycobacterium leprae (strain TN) OX=272631 GN=pssA ... Belongs to the CDP-alcohol phosphatidyltransferase class-I family.Curated. Keywords - Domaini. Transmembrane, Transmembrane ... 1,2-diacyl-sn-glycero-3-phospho-L-serine*Search proteins in UniProtKB for this molecule. ...
CDPdiacylglycerol-Serine O-Phosphatidyltransferase * Electron Transport Complex I Grant support * MT 15460/Canadian Institutes ...
CDP-diacylglycerol-serine O-phosphatidyltransferase (pss; comp44746_c0), and two phosphatidylserine decarboxylase proenzymes ( ... one CDP-diacylglycerol-serine O-phosphatidyltransferase transcript (encoded by pss) displayed significantly decreased ... CDP-diacylglycerol-serine O-phosphatidyltransferase; psd, phosphatidylserine decarboxylase proenzyme; chl, magnesium-chelatase ... Serine/threonine-protein kinases are crucial components of diverse signaling pathways and for regulation of cell proliferation ...
... is replaced by L-serine. PTDSS2 is specific for phosphatatidylethanolamine and does not act on phosphatidylcholine. ... CDP-diacylglycerol-serine O-phosphatidyltransferase activity Source: Ensembl. *L-serine-phosphatidylethanolamine ... KM=120 µM for serine (in the presence of 1 mM PE)1 Publication. Manual assertion based on experiment ini ... DB00144, Phosphatidyl serine. Polymorphism and mutation databases. BioMuta curated single-nucleotide variation and disease ...
CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8]. K00999 CDP-diacylglycerol--inositol 3- ... CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8]. K17879 peroxisomal coenzyme A diphosphatase NUDT7 [EC:3.6.1 ... CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5]. K00997 holo-[acyl-carrier protein] synthase [ ...
Serine-phosphoethanolamine synthase Pages 35-38 * CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase ...
CDPdiacylglycerol-Serine O-PhosphatidyltransferaseIBA 01/01/2014 - "Gain-of-function mutations in the phosphatidylserine ...
CDP-diacylglycerol/serine O-phosphatidyltransferase [Rh. 1. 2e-72. 86357048. 281. CDP-diacylglycerol-serine O- ... serine O-phosphatidyltransferase; InterPro: IPR004533 This enzyme, CDP-diacylglycerol--serine O-phosphatidyltransferase, is ... 0003882 CDP-diacylglycerol-serine O-phosphatidyltransferase activity, 0008654 phospholipid biosynthetic process, 0046341 CDP- ... CDP-diacylglycerol/serine O-phosphatidyltransferase [Rh. 1. 8e-72. >gi,315121771,ref,YP_004062260.1, phosphatidylserine ...
... upregulated via increased levels of phosphatidylserine decarboxylase and CDP-diacylglycerol-serine O-phosphatidyltransferase. ... and a trypsin-like serine protease suggest that individual amino acids along with proteins may be broken down for use as ...
CDP-diacylglycerol--serine O-phosphatidyltransferase. Alternative Name(s). CDP-diglycerine-serine O-phosphatidyltransferase.. ...
CDP-DIACYLGLYCEROL - SERINE O-PHOSPHATIDYLTRANSFERASE (EC 2.7.8.8) (PHOSPHATIDYLSERINE SYNTHASE).. OS006763.1_at. gb,Z95637 ...
"CDP-diacylglycerol--serine FT /gene_family="HOG000270167" [ FAMILY / ALN / TREE ] FT O-phosphatidyltransferase" FT /codon_start ... "serine acetyltransferase" FT /gene_family="HOG000049437" [ FAMILY / ALN / TREE ] FT /codon_start="1" FT /locus_tag="VVM_00433" ... "serine/threonine protein kinase" FT /transl_table="11" FT /db_xref="GI:320154918" FT /db_xref="GeneID:10164778" FT /translation ... "serine--pyruvate FT /gene_family="HOG000171815" [ FAMILY / ALN / TREE ] FT aminotransferase/L-alanine:glyoxylate ...
... serine ethanolaminephosphotransferase EC 2.7.8.5: CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase EC 2.7.8.6 ... CDP-diacylglycerol-serine O-phosphatidyltransferase EC 2.7.8.9: phosphomannan mannosephosphotransferase EC 2.7.8.10: ... CDP-diacylglycerol-choline O-phosphatidyltransferase EC 2.7.8.25: triphosphoribosyl-dephospho-CoA synthase EC 2.7.8.26: ... L-serine-phosphatidylethanolamine phosphatidyltransferase EC 2.7.8.30: undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose ...
CDPdiacylglycerol-serine O-phosphatidyl-transferase Current Synonym true false 8463019 Phosphatidylserine synthase Current ... Cytidine diphosphate (CDP) diacylglycerol-serine O-phosphatidyl-transferase Current Synonym true false 2913579016 Cytidine ... Cytidine diphosphate diacylglycerol-serine O-phosphatidyl-transferase (substance). Code System Preferred Concept Name. Cytidine ... diphosphate diacylglycerol-serine O-phosphatidyl-transferase Current Synonym true false 8462012 ...
CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase. *CDP-diacylglycerol-serine O-phosphatidyltransferase. *CDP- ... protein serine/threonine kinase activity. • GO:0001948 protein binding. • insulin receptor substrate binding. • ATP binding. • ... positive regulation of peptidyl-serine phosphorylation. • platelet activation. • Fc-epsilon receptor signaling pathway. • ...
CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase. *CDP-diacylglycerol-serine O-phosphatidyltransferase. *CDP- ...
CDPdiacylglycerol-Serine O-Phosphatidyltransferase. *Phosphoric Monoester Hydrolases. Secondary source IDs. *GENBANK/D16444 ...
CDP-diacylglycerol--serine O-phosphatidyltransferase. External Links:. Resource. Link. References:. Not Available. This project ... L-Serine. +. → +. Cytidine monophosphate. +. +. CDP-DG(12:0/14:0) + L-Serine + L-Serine → PS(12:0/14:0(3-OH)) + Cytidine ...
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase. CDP-diacylglycerol--serine O-phosphatidyltransferase. ... L-Serine. H. +. Cytidine. monophosphate. PS(19:iso/18:1(9Z)). Glycerol. 3-phosphate. H. +. Cytidine. monophosphate. PG(16:1(9Z ... serine O-. phosphatidyltransferase. CDP-. diacylglycerol-. -glycerol-3-. phosphate 3-. phosphatidyltransferase. Putative. ... L-Serine. Hydrogen Ion. Cytidine. monophosphate. PS(19:iso/18:1(9Z)). Glycerol. 3-phosphate. Hydrogen Ion. Cytidine. ...
CDP-diacylglycerol--serine O-phosphatidyltransferase 145, 308. DVU3061. sensory box histidine kinase 55, 308. ...
CDP-diacylglycerol--serine O-phosphatidyltransferase 28, 66. MMP1185. hydrogen uptake protein:hydrogenase maturation protease ...
CDP-diacylglycerol--serine O-phosphatidyltransferase. External Links:. Resource. Link. References:. Not Available. This project ... L-Serine. +. → +. Cytidine monophosphate. +. +. CDP-DG(10:0/19:1(9Z)) + L-Serine + L-Serine → PS(10:0(3-OH)/19:iso) + Cytidine ...
CDP-diacylglycerol--serine O-phosphatidyltransferase; Identified by match to protein family HMM PF01066; match to protein ... CDP-diacylglycerol--serine O-phosphatidyltransferase; Identified by match to protein family HMM PF01066; match to protein ... CDP-diacylglycerol--serine O-phosphatidyltransferase; Identified by match to protein family HMM PF01066; match to protein ... CDP-diacylglycerol--serine O-phosphatidyltransferase; Identified by match to protein family HMM PF01066; match to protein ...
CDP-diacylglycerol--serine O-phosphatidyltransferase; Phosphatidylserine synthase; Belongs to the CDP-alcohol ... CDP-diacylglycerol--serine O-phosphatidyltransferase; Phosphatidylserine synthase; Belongs to the CDP-alcohol ... Belongs to the CDP-alcohol phosphatidyltransferase class-I family (241 aa) ... Belongs to the CDP-alcohol phosphatidyltransferase class-I family ...
CDP-diacylglycerol--serine O-phosphatidyltransferase. ProteinCard. P17444. Choline dehydrogenase. ProteinCard. P0A9T0. D-3- ...
CDP-diacylglycerol--serine O-phosphatidyltransferase. Enzyme. *L-Serine. *Cytidine monophosphate. *hydron. P42941. SER2. ... O-Phospho-L-serine. 407-41-0. (2S)-2-amino-3-(phosphonooxy)propanoic acid. C3H8NO6P. 185.0725. ... L-Serine. 56-45-1. (2S)-2-amino-3-hydroxypropanoic acid. C3H7NO3. 105.0926. ... D-Serine. 312-84-5. (2R)-2-amino-3-hydroxypropanoic acid. C3H7NO3. 105.0926. ...
pssA CDP-diacylglycerol-serine O phosphatidyltransferase. 726. HVO_1144. 1144. chromosome. 1045259 → 1045706. pcy cytochrome- ...
pssA CDP-diacylglycerol-serine O phosphatidyltransferase. 1144. HVO_1144. 448. pcy cytochrome-like protein. ...
  • This enzyme participates in glycine, serine and threonine metabolism and glycerophospholipid metabolism. (wikipedia.org)
  • Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. (string-db.org)
  • In enzymology, a CDP-diacylglycerol-serine O-phosphatidyltransferase (EC 2.7.8.8) is an enzyme that catalyzes the chemical reaction CDP-diacylglycerol + L-serine ⇌ {\displaystyle \rightleftharpoons } CMP + (3-sn-phosphatidyl)-L-serine Thus, the two substrates of this enzyme are CDP-diacylglycerol and L-serine, whereas its two products are CMP and (3-sn-phosphatidyl)-L-serine. (wikipedia.org)
  • The systematic name of this enzyme class is CDP-diacylglycerol:L-serine 3-sn-phosphatidyltransferase. (wikipedia.org)
  • Sphingoid bases and the serine catabolic enzyme CHA1 define a novel feedforward/feedback mechanism in the response to serine availability. (semanticscholar.org)
  • SERINC2 (Serine Incorporator 2) is a Protein Coding gene. (genecards.org)
  • Bacterial adhesion and biofilm formation are mediated by long peritrichous fimbriae that are composed of a 200 kDa serine rich glycoprotein named Fap1 (fimbriae-associated protein). (beds.ac.uk)
  • Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. (uniprot.org)
  • The findings that the fap1 -like loci are widespread among Gram-positive bacteria suggest that there is a common mechanism in the biogenesis of serine-rich glycoproteins. (beds.ac.uk)
  • Molecular cloning of the gene encoding CDPdiacylglycerol-inositol 3-phosphatidyl transferase in Saccharomyces cerevisiae. (wikipathways.org)
  • GO annotations related to this gene include L-serine transmembrane transporter activity . (genecards.org)
  • CLK family members have been shown to interact with, and phosphorylate, serine- and arginine-rich (SR) proteins of the spliceosomal complex, which is a part of the regulatory mechanism that enables the SR proteins to control RNA splicing. (antibodies-online.com)