CCAAT-Binding Factor: A heterotrimeric DNA-binding protein that binds to CCAAT motifs in the promoters of eukaryotic genes. It is composed of three subunits: A, B and C.CCAAT-Enhancer-Binding Proteins: A class of proteins that were originally identified by their ability to bind the DNA sequence CCAAT. The typical CCAAT-enhancer binding protein forms dimers and consists of an activation domain, a DNA-binding basic region, and a leucine-rich dimerization domain (LEUCINE ZIPPERS). CCAAT-BINDING FACTOR is structurally distinct type of CCAAT-enhancer binding protein consisting of a trimer of three different subunits.Core Binding Factors: Heterodimeric transcription factors containing a DNA-binding alpha subunits, (CORE BINDING FACTOR ALPHA SUBUNITS), along with a non-DNA-binding beta subunits, CORE BINDING FACTOR BETA SUBUNIT. Core Binding Factor regulates GENETIC TRANSCRIPTION of a variety of GENES involved primarily in CELL DIFFERENTIATION and CELL CYCLE progression.NFI Transcription Factors: Transcription factors that were originally identified as site-specific DNA-binding proteins essential for DNA REPLICATION by ADENOVIRUSES. They play important roles in MAMMARY GLAND function and development.Y-Box-Binding Protein 1: Y-box-binding protein 1 was originally identified as a DNA-binding protein that interacts with Y-box PROMOTER REGIONS of MHC CLASS II GENES. It is a highly conserved transcription factor that regulates expression of a wide variety of GENES.DNA-Binding Proteins: Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases.Transcription Factors: Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Promoter Regions, Genetic: DNA sequences which are recognized (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. Highly conserved sequences within the promoter include the Pribnow box in bacteria and the TATA BOX in eukaryotes.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Core Binding Factor beta Subunit: A non-DNA binding transcription factor that is a subunit of core binding factor. It forms heterodimeric complexes with CORE BINDING FACTOR ALPHA SUBUNITS, and regulates GENETIC TRANSCRIPTION of a variety of GENES involved primarily in CELL DIFFERENTIATION and CELL CYCLE progression.Pol1 Transcription Initiation Complex Proteins: Factors that form a preinitiation complex at promoters that are specifically transcribed by RNA POLYMERASE I.Core Binding Factor alpha Subunits: A family of transcription factors that bind to the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. Family members contain a highly conserved DNA-binding domain known as the runt domain. They can act as both activators and repressors of expression of GENES involved in CELL DIFFERENTIATION and CELL CYCLE progression.Telomeric Repeat Binding Protein 1: A ubiquitously expressed telomere-binding protein that is present at TELOMERES throughout the CELL CYCLE. It is a suppressor of telomere elongation and may be involved in stabilization of telomere length. It is structurally different from TELOMERIC REPEAT BINDING PROTEIN 2 in that it contains acidic N-terminal amino acid residues.G-Box Binding Factors: A family of transcription factors found primarily in PLANTS that bind to the G-box DNA sequence CACGTG or to a consensus sequence CANNTG.CCAAT-Enhancer-Binding Protein-beta: A CCAAT-enhancer-binding protein found in LIVER; INTESTINES; LUNG and ADIPOSE TISSUE. It is an important mediator of INTERLEUKIN-6 signaling.Transcription, Genetic: The biosynthesis of RNA carried out on a template of DNA. The biosynthesis of DNA from an RNA template is called REVERSE TRANSCRIPTION.Core Binding Factor Alpha 2 Subunit: A transcription factor that dimerizes with the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain. Runx1 is frequently mutated in human LEUKEMIAS.Goats: Any of numerous agile, hollow-horned RUMINANTS of the genus Capra, in the family Bovidae, closely related to the SHEEP.CCAAT-Enhancer-Binding Protein-alpha: A CCAAT-enhancer-binding protein found in LIVER; ADIPOSE TISSUE; INTESTINES; LUNG; ADRENAL GLANDS; PLACENTA; OVARY and peripheral blood mononuclear cells (LEUKOCYTES, MONONUCLEAR). Experiments with knock-out mice have demonstrated that CCAAT-enhancer binding protein-alpha is essential for the functioning and differentiation of HEPATOCYTES and ADIPOCYTES.CCAAT-Enhancer-Binding Protein-delta: A member of the C-EBP protein family of transcription factors. It plays a key role in G0 PHASE mammary EPITHELIAL CELL growth arrest, and it is involved in transcriptional regulation of INTERLEUKIN 1; INTERLEUKIN 6; and TUMOR NECROSIS FACTOR-ALPHA.Enhancer Elements, Genetic: Cis-acting DNA sequences which can increase transcription of genes. Enhancers can usually function in either orientation and at various distances from a promoter.Antibodies: Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only with the ANTIGEN (or a very similar shape) that induced their synthesis in cells of the lymphoid series (especially PLASMA CELLS).Magnaporthe: A genus of FUNGI, in the family Magnaporthaceae of uncertain position (incertae sedis). It is best known for its species, M. grisea, which is one of the most popular experimental organisms of all fungal plant pathogens. Its anamorph is PYRICULARIA GRISEA.Oryza sativa: Annual cereal grass of the family POACEAE and its edible starchy grain, rice, which is the staple food of roughly one-half of the world's population.Plant Diseases: Diseases of plants.Botany: The study of the origin, structure, development, growth, function, genetics, and reproduction of plants.Aspergillus oryzae: An imperfect fungus present on most agricultural seeds and often responsible for the spoilage of seeds in bulk storage. It is also used in the production of fermented food or drink, especially in Japan.Mycelium: The body of a fungus which is made up of HYPHAE.Spores, Fungal: Reproductive bodies produced by fungi.Theaceae: A plant family of the order THEALES, subclass Dilleniidae, class Magnoliopsida, best known for CAMELLIA SINENSIS, which is the source of Oriental TEA.Quinolinium CompoundsFluorescent Dyes: Agents that emit light after excitation by light. The wave length of the emitted light is usually longer than that of the incident light. Fluorochromes are substances that cause fluorescence in other substances, i.e., dyes used to mark or label other compounds with fluorescent tags.HydrazinesOrganic Chemicals: A broad class of substances containing carbon and its derivatives. Many of these chemicals will frequently contain hydrogen with or without oxygen, nitrogen, sulfur, phosphorus, and other elements. They exist in either carbon chain or carbon ring form.Fluorescence: The property of emitting radiation while being irradiated. The radiation emitted is usually of longer wavelength than that incident or absorbed, e.g., a substance can be irradiated with invisible radiation and emit visible light. X-ray fluorescence is used in diagnosis.Antibodies, Monoclonal: Antibodies produced by a single clone of cells.Influenzavirus A: A genus in the family ORTHOMYXOVIRIDAE causing influenza and other diseases in humans and animals. It contains many strains as well as antigenic subtypes of the integral membrane proteins hemagglutinin (HEMAGGLUTININS) and NEURAMINIDASE. The type species is INFLUENZA A VIRUS.Recombinant Proteins: Proteins prepared by recombinant DNA technology.Antibody Specificity: The property of antibodies which enables them to react with some ANTIGENIC DETERMINANTS and not with others. Specificity is dependent on chemical composition, physical forces, and molecular structure at the binding site.Immunoglobulin Fab Fragments: Univalent antigen-binding fragments composed of one entire IMMUNOGLOBULIN LIGHT CHAIN and the amino terminal end of one of the IMMUNOGLOBULIN HEAVY CHAINS from the hinge region, linked to each other by disulfide bonds. Fab contains the IMMUNOGLOBULIN VARIABLE REGIONS, which are part of the antigen-binding site, and the first IMMUNOGLOBULIN CONSTANT REGIONS. This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.Antibodies, Viral: Immunoglobulins produced in response to VIRAL ANTIGENS.Search Engine: Software used to locate data or information stored in machine-readable form locally or at a distance such as an INTERNET site.Databases, Genetic: Databases devoted to knowledge about specific genes and gene products.Genome, Human: The complete genetic complement contained in the DNA of a set of CHROMOSOMES in a HUMAN. The length of the human genome is about 3 billion base pairs.Setaria Plant: A plant genus of the family POACEAE. The small pointed seeds are grown for hay in North America and western Europe and important as food in China and other Asian countries.Setaria Nematode: A genus of parasitic nematodes found in the peritoneal cavity of wild or domestic cattle or equines.Sorghum: A plant genus of the family POACEAE. The grain is used for FOOD and for ANIMAL FEED. This should not be confused with KAFFIR LIME or with KEFIR milk product.Panicum: A plant genus of the family POACEAE. The seed is one of the EDIBLE GRAINS used in millet cereals and in feed for birds and livestock (ANIMAL FEED). It contains diosgenin (SAPONINS).Poaceae: A large family of narrow-leaved herbaceous grasses of the order Cyperales, subclass Commelinidae, class Liliopsida (monocotyledons). Food grains (EDIBLE GRAIN) come from members of this family. RHINITIS, ALLERGIC, SEASONAL can be induced by POLLEN of many of the grasses.Pulvinus: A group of cells at the base of a leaf in certain plants that, by rapidly losing water, brings about changes in the position of the leaves. (Concise Dictionary of Biology, 1990)Flowers: The reproductive organs of plants.

Transcriptional regulation of the squalene synthase gene (ERG9) in the yeast Saccharomyces cerevisiae. (1/416)

The ergosterol biosynthetic pathway is a specific branch of the mevalonate pathway. Since the cells requirement for sterols is greater than for isoprenoids, sterol biosynthesis must be regulated independently of isoprenoid biosynthesis. In this study we explored the transcriptional regulation of squalene synthase (ERG9) in Saccharomyces cerevisiae, the first enzyme dedicated to the synthesis of sterols. A mutant search was performed to identify genes that were involved in the regulation of the expression of an ERG9-lacZ promoter fusion. Mutants with phenotypes consistent with known sterol biosynthetic mutations (ERG3, ERG7, ERG24) increased expression of ERG9. In addition, treatment of wild-type cells with the sterol inhibitors zaragozic acid and ketoconazole, which target squalene synthase and the C-14 sterol demethylase respectively, also caused an increase in ERG9 expression. The data also demonstrate that heme mutants increased ERG9 expression while anaerobic conditions decreased expression. Additionally, the heme activator protein transcription factors HAP1 and HAP2/3/4, the yeast activator protein transcription factor yAP-1, and the phospholipid transcription factor complex INO2/4 regulate ERG9 expression. ERG9 expression is decreased in hap1, hap2/3/4, and yap-1 mutants while ino2/4 mutants showed an increase in ERG9 expression. This study demonstrates that ERG9 transcription is regulated by several diverse factors, consistent with the idea that as the first step dedicated to the synthesis of sterols, squalene synthase gene expression and ultimately sterol biosynthesis is highly regulated.  (+info)

Down-regulation of cyclin B1 gene transcription in terminally differentiated skeletal muscle cells is associated with loss of functional CCAAT-binding NF-Y complex. (2/416)

The observation that cyclin B1 protein and mRNAs are down-regulated in terminally differentiated (TD) C2C12 cells, suggested us to investigate the transcriptional regulation of the cyclin B1 gene in these cells. Transfections of cyclin B1 promoter constructs indicate that two CCAAT boxes support cyclin B1 promoter activity in proliferating cells. EMSAs demonstrate that both CCAAT boxes are recognized by the trimeric NF-Y complex in proliferating but not in TD cells. Transfecting a dominant-negative mutant of NF-YA we provide evidence that NF-Y is required for maximal promoter activity. Addition of recombinant NF-YA to TD C2C12 nuclear extracts restores binding activity in vitro, thus indicating that the loss of NF-YA in TD cells is responsible for the lack of the NF-Y binding to the CCAAT boxes. Consistent with this, we found that the NF-YA protein is absent in TD C2C12 cells. In conclusion, our data demonstrate that NF-Y is required for cyclin B1 promoter activity. We also demonstrate that cyclin B1 expression is regulated at the transcriptional level in TD C2C12 cells and that the switch-off of cyclin B1 promoter activity in differentiated cells depends upon the loss of a functional NF-Y complex. In particular the loss of NF-YA protein is most likely responsible for its inactivation.  (+info)

Activation domain-mediated targeting of the SWI/SNF complex to promoters stimulates transcription from nucleosome arrays. (3/416)

The yeast SWI/SNF complex is required for the transcription of several yeast genes and has been shown to alter nucleosome structure in an ATP-dependent reaction. In this study, we show that the complex stimulated in vitro transcription from nucleosome templates in an activation domain-dependent manner. Transcription stimulation by SWI/SNF required an activation domain with which it directly interacts. The acidic activation domains of VP16, Gcn4, Swi5, and Hap4 interacted directly with the purified SWI/SNF complex and with the SWI/SNF complex in whole-cell extracts. The similarity of activation domain interactions and transcriptional stimulation between SWI/SNF and the SAGA histone acetyltransferase complex may account for their apparent overlapping functions in vivo.  (+info)

Identification of proteins that interact with NF-YA. (4/416)

We used the yeast two-hybrid system to show that the serum response factor (SRF) and zinc-fingers and homeobox 1 (ZHXI) proteins interact with the A subunit of nuclear factor-Y (NF-YA). GST pulldown assays revealed that both proteins interact specifically with NF-YA in vitro. Amino acids located between 272 and 564, a region that contains two homeodomains, are required for the interaction of ZHX1 with NF-YA. Two different domains of NF-YA, a glutamine-rich region and a serine/threonine-rich region, are necessary for the interactions with ZHX1 and SRF, respectively.  (+info)

A nuclear factor Y (NFY) site positively regulates the human CD34 stem cell gene. (5/416)

Proper regulation of the human CD34 gene requires a combinatorial action of multiple proximal and long-range, cis elements. This report shows that, like the murine CD34 5' untranslated region (UTR), the corresponding region of the human CD34 gene is necessary for optimal promoter activity. We localized the most critical element of this region to base pairs +48/+75. Through oligonucleotide competition and antibody supershift experiments in electrophoretic mobility shift assays, we found that this sequence contains a binding site (CCAAT box) for the transcription factor NFY (nuclear factor Y), a factor mediating cell type-specific and cell-cycle regulated expression of genes. Mutating this site led to a 5-fold decrease in CD34 promoter activity in transient transfection experiments. Interestingly, NFY binds adjacently to the earlier identified c-myb binding site. Here we show that both binding sites are important for CD34 promoter function: mutating either site alone decreased CD34 promoter-driven reporter gene activity 4-fold. We also show that the integrity of the c-myb binding site is necessary for stabilization of NFY binding to its site. Such cooperation between c-myb, which is expressed in early hematopoietic cells, and NFY, which is expressed in many cell types, might contribute to specific activation of CD34 in stem cells. The CCAAT box motif was also noted in the 5' UTR of the murine CD34 gene, however, NFY did not bind to this region. Thus, our results indicate that the functional similarities between the human and murine CD34 5' UTRs are achieved through different molecular mechanism(s).  (+info)

Identification and characterization of basal and cyclic AMP response elements in the promoter of the rat GTP cyclohydrolase I gene. (6/416)

5812 base pairs of rat GTP cyclohydrolase I (GTPCH) 5'-flanking region were cloned and sequenced, and the transcription start site was determined for the gene in rat liver. Progressive deletion analysis using transient transfection assays of luciferase reporter constructs defined the core promoter as a highly conserved 142-base pair GC-rich sequence upstream from the cap site. DNase I footprint analysis of this region revealed (5' --> 3') a Sp1/GC box, a noncanonical cAMP-response element (CRE), a CCAAT-box, and an E-box. Transcription from the core promoter in PC12 but not C6 or Rat2 cells was enhanced by incubation with 8-bromo-cyclic AMP. Mutagenesis showed that both the CRE and CCAAT-box independently contribute to basal and cAMP-dependent activity. The combined CRE and CCAAT-box cassette was also found to enhance basal transcription and confer cAMP sensitivity on a heterologous minimal promoter. The addition of the Sp1/GC box sequence to this minimal promoter construct inhibited basal transcription without affecting the cAMP response. EMSA showed that nuclear proteins from PC12 but not C6 or Rat2 cells bind the CRE as a complex containing activating transcription factor (ATF)-4 and CCAAT enhancer-binding protein beta, while both PC12 and C6 cell nuclear extracts were recruited by the CCAAT-box as a complex containing nuclear factor Y. Overexpression of ATF-4 in PC12 cells was found to transactivate the GTPCH promoter response to cAMP. These studies suggest that the elements required for cell type-specific cAMP-dependent enhancement of gene transcription are located along the GTPCH core promoter and include the CRE and adjacent CCAAT-box and the proteins ATF-4, CCAAT enhancer-binding protein beta, and nuclear factor Y.  (+info)

Sterol regulation of human fatty acid synthase promoter I requires nuclear factor-Y- and Sp-1-binding sites. (7/416)

To understand cholesterol-mediated regulation of human fatty acid synthase promoter I, we tested various 5'-deletion constructs of promoter I-luciferase reporter gene constructs in HepG2 cells. The reporter gene constructs that contained only the Sp-1-binding site (nucleotides -82 to -74) and the two tandem sterol regulatory elements (SREs; nucleotides -63 to -46) did not respond to cholesterol. Only the reporter gene constructs containing a nuclear factor-Y (NF-Y) sequence, the CCAAT sequence (nucleotides -90 to -86), an Sp-1 sequence, and the two tandem SREs responded to cholesterol. The NF-Y-binding site, therefore, is essential for cholesterol response. Mutating the SREs or the NF-Y site and inserting 4 bp between the Sp-1- and NF-Y-binding sites both resulted in a minimal cholesterol response of the reporter genes. Electrophoretic mobility-shift assays using anti-SRE-binding protein (SREBP) and anti-NF-Ya antibodies confirmed that these SREs and the NF-Y site bind the respective factors. We also identified a second Sp-1 site located between nucleotides -40 and -30 that can substitute for the mutated Sp-1 site located between nucleotides -82 and -74. The reporter gene expression of the wild-type promoter and the Sp-1 site (nucleotides -82 to -74) mutant promoter was similar when SREBP1a [the N-terminal domain of SREBP (amino acids 1-520)] was constitutively overexpressed, suggesting that Sp-1 recruits SREBP to the SREs. Under the same conditions, an NF-Y site mutation resulted in significant loss of reporter gene expression, suggesting that NF-Y is required to activate the cholesterol response.  (+info)

Redirection of the respiro-fermentative flux distribution in Saccharomyces cerevisiae by overexpression of the transcription factor Hap4p. (8/416)

Reduction of aerobic fermentation on sugars by altering the fermentative/oxidative balance is of significant interest for optimization of industrial production of Saccharomyces cerevisiae. Glucose control of oxidative metabolism in baker's yeast is partly mediated through transcriptional regulation of the Hap4p subunit of the Hap2/3/4/5p transcriptional activator complex. To alleviate glucose repression of oxidative metabolism, we constructed a yeast strain with constitutively elevated levels of Hap4p. Genetic analysis of expression levels of glucose-repressed genes and analysis of respiratory capacity showed that Hap4p overexpression (partly) relieves glucose repression of respiration. Analysis of the physiological properties of the Hap4p overproducer in batch cultures in fermentors (aerobic, glucose excess) has shown that the metabolism of this strain is more oxidative than in the wild-type strain, resulting in a significant reduced ethanol production and improvement of growth rate and a 40% gain in biomass yield. Our results show that modification of one or more transcriptional regulators can be a powerful and a widely applicable tool for redirection of metabolic fluxes in microorganisms.  (+info)

*CCAAT/enhancer binding protein zeta

"A cloned human CCAAT-box-binding factor stimulates transcription from the human hsp70 promoter". Mol Cell Biol. 10 (12): 6709- ... CCAAT/enhancer-binding protein zeta is a protein that in humans is encoded by the CEBPZ gene. CCAAT/enhancer binding protein ... "Cloning and characterization of mouse CCAAT binding factor". Nucleic Acids Res. 24 (6): 1091-8. doi:10.1093/nar/24.6.1091. PMC ... "Physical interaction of tumour suppressor p53/p73 with CCAAT-binding transcription factor 2 (CTF2) and differential regulation ...

*CAAT box

... the core binding factor (CBF)-DNA complex retains a high degree of conservation within the CCAAT binding motif, as well as the ... Protein specific binding is required for the CCAAT box activation. These proteins are known as CCAAT box binding proteins/CCAAT ... "DNA Binding Specificity of the CCAAT-binding Factor CBF/NF-Y". The Journal of Biological Chemistry. 272 (42): 26562-26572. doi: ... Another aspect of the CCAAT binding motif is the CCAAT/enhancer binding proteins (C/EBPs). They are a group of transcription ...

*NFYA

Mantovani R (October 1999). "The molecular biology of the CCAAT-binding factor NF-Y". Gene. 239 (1): 15-27. doi:10.1016/S0378- ... forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. ... chain of a rat heteromeric CCAAT-binding protein. Sequence identity with the yeast HAP3 transcription factor". The Journal of ... "Evolutionary variation of the CCAAT-binding transcription factor NF-Y". Nucleic Acids Research. 20 (5): 1087-91. doi:10.1093/ ...

*NFYB

Mantovani R (1999). "The molecular biology of the CCAAT-binding factor NF-Y". Gene. 239 (1): 15-27. doi:10.1016/S0378-1119(99) ... forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a ... "Evolutionary variation of the CCAAT-binding transcription factor NF-Y". Nucleic Acids Res. 20 (5): 1087-91. doi:10.1093/nar/ ... "The B subunit of the CAAT-binding factor NFY binds the central segment of the Co-activator p300". J. Biol. Chem. 274 (12): 7623 ...

*NFYC

Chattopadhyay C, Hawke D, Kobayashi R, Maity SN (2004). "Human p32, interacts with B subunit of the CCAAT-binding factor, CBF/ ... Mantovani R (1999). "The molecular biology of the CCAAT-binding factor NF-Y". Gene. 239 (1): 15-27. doi:10.1016/S0378-1119(99) ... Martinelli R, Heintz N (1994). "H1TF2A, the large subunit of a heterodimeric, glutamine-rich CCAAT-binding transcription factor ... "The NF-YB/NF-YC structure gives insight into DNA binding and transcription regulation by CCAAT factor NF-Y". J. Biol. Chem. 278 ...

*ING2

Chattopadhyay C, Hawke D, Kobayashi R, Maity SN (2004). "Human p32, interacts with B subunit of the CCAAT-binding factor, CBF/ ...

*NFIX

"Entrez Gene: NFIX nuclear factor I/X (CCAAT-binding transcription factor)". Singh SK, Bhardwaj R, Wilczynska KM, Dumur CI, ... gene expression is mediated by decreased DNA binding of nuclear factor I proteins which control constitutive TTF-1 expression ... for the human transcription factor nuclear factor I by FISH". Genomics. 28 (1): 66-73. doi:10.1006/geno.1995.1107. PMID 7590749 ... Nuclear factor 1 X-type is a protein that in humans is encoded by the NFIX gene. NFI-X3, a splice variant of NFIX, regulates ...

*NFIC (gene)

"Entrez Gene: NFIC nuclear factor I/C (CCAAT-binding transcription factor)". Blau J, Xiao H, McCracken S, et al. (1996). "Three ... "A family of human CCAAT-box-binding proteins active in transcription and DNA replication: cloning and expression of multiple ... for the human transcription factor nuclear factor I by FISH". Genomics. 28 (1): 66-73. doi:10.1006/geno.1995.1107. PMID 7590749 ... Nuclear factor 1 C-type is a protein that in humans is encoded by the NFIC gene. GRCh38: Ensembl release 89: ENSG00000141905 - ...

*Collagen, type XI, alpha 1

2003). "The transcription factor CCAAT-binding factor CBF/NF-Y regulates the proximal promoter activity in the human alpha 1(XI ...

*Collagen, type V, alpha 3

2004). "The transcription factor CCAAT-binding factor CBF/NF-Y and two repressors regulate the core promoter of the human pro- ... Kypreos KE, Sonenshein GE (1998). "Basic fibroblast growth factor decreases type V/XI collagen expression in cultured bovine ...

*CEBPB

Serum response factor, SMARCA2, Sp1 transcription factor, TRIM28, and Zif268. Ccaat-enhancer-binding proteins GRCh38: Ensembl ... Chen GK, Sale S, Tan T, Ermoian RP, Sikic BI (April 2004). "CCAAT/enhancer-binding protein beta (nuclear factor for interleukin ... Hanlon M, Sealy L (May 1999). "Ras regulates the association of serum response factor and CCAAT/enhancer-binding protein beta ... "Tumor Necrosis Factor Alpha Inhibits Type I Collagen Synthesis through Repressive CCAAT/Enhancer-Binding Proteins". Mol. Cell. ...

*Ccaat-enhancer-binding proteins

"Structural basis for DNA recognition by the basic region leucine zipper transcription factor CCAAT/enhancer-binding protein ... "CCAAT/enhancer-binding protein family members recruit the coactivator CREB-binding protein and trigger its phosphorylation". ... CCAAT-enhancer-binding proteins (or C/EBPs) is a family of transcription factors composed of six members, named from C/EBPα to ... Freytag SO, Paielli DL, Gilbert JD (Jul 1994). "Ectopic expression of the CCAAT/enhancer-binding protein alpha promotes the ...

*Haematopoiesis

... is transcription factor CCAAT-enhancer binding protein α (C/EBPα). Mutations in C/EBPα are associated with acute myeloid ... One of the key players in self-renewal and development of haematopoietic cells is stem cell factor (SCF), which binds to the c- ... Granulocyte colony-stimulating factor Granulocyte macrophage colony-stimulating factor Leukocyte extravasation Birbrair, ... Very important finding is, that different zinc fingers are involved in binding to different place in DNA and this is the reason ...

*Serum response factor

Hanlon M, Sealy L (May 1999). "Ras regulates the association of serum response factor and CCAAT/enhancer-binding protein beta ... Serum response factor, also known as SRF, is a transcription factor protein. Serum response factor is a member of the MADS ( ... Serum response factor has been shown to interact with: ASCC3, ATF6, CEBPB, CREB-binding protein, ELK4, GATA4, GTF2F1, GTF2I, ... interaction between the MADS box of serum response factor and the TEA/ATTS DNA-binding domain of transcription enhancer factor- ...

*Neutrophil-specific granule deficiency

CCAAT/enhancer-binding protein epsilon) gene, a transcription factor primarily active in myeloid cells. Almost all patients ... granule deficiency results from a novel mutation with loss of function of the transcription factor CCAAT/enhancer binding ... Khanna-Gupta A, Sun H, Zibello T, Lee HM, Dahl R, Boxer LA, Berliner N (2007). "Growth factor independence-1 (Gfi-1) plays a ...

*CEBPE

... granule deficiency results from a novel mutation with loss of function of the transcription factor CCAAT/enhancer binding ... CCAAT/enhancer binding protein (C/EBP), epsilon, also known as CEBPE and CRP1, is a type of ccaat-enhancer-binding protein. ... The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions ... Nakajima H, Watanabe N, Shibata F, Kitamura T, Ikeda Y, Handa M (May 2006). "N-terminal region of CCAAT/enhancer-binding ...

*U7 small nuclear RNA

"U7 snRNA acts as a transcriptional regulator interacting with an inverted CCAAT sequence-binding transcription factor NF-Y". ... dual binding contacts with the 100 kDa zinc finger processing factor (ZFP100) and a ZFP100-independent function in histone RNA ... The binding of the HDE region by the U7 snRNA, through complementary base-pairing, is an important step for the future ... Jaeger S, Martin F, Rudinger-Thirion J, Giegé R, Eriani G (2006). "Binding of human SLBP on the 3'-UTR of histone precursor H4- ...

*TP53

"Physical interaction of tumour suppressor p53/p73 with CCAAT-binding transcription factor 2 (CTF2) and differential regulation ... Lo KW, Kan HM, Chan LN, Xu WG, Wang KP, Wu Z, Sheng M, Zhang M (March 2005). "The 8-kDa dynein light chain binds to p53-binding ... Afterwards there is the DNA binding domain (DBD), which enables the proteins to sequence specific binding. The carboxyl ... which prevents Mdm2-binding even more. Phosphorylation also allows for binding of transcriptional coactivators, like p300 and ...

*Transmembrane protein 251

No vertebrate TATA binding protein factors, RNA polymerase transcription factor II B, CCAAT binding factors, or CCAAT enhancer ... Various transcription factors are predicted to bind within the conserved parts of the promoter (upstream regulatory) region, on ... The transcription factors with the highest matrix scores include NKX homeodomain factors, GATA-binding factors, two-handed zinc ... Over-expression of the TMEM251 gene has not been linked as a causal factor in any of these disease states The conditions under ...

*PDK4

... family is tightly regulated itself by a myriad of factors including transcription factors Sp1 and CCAAT box binding factor (CBF ... When the TPP coenzyme is bound, the rates of phosphorylation by all four isozymes are drastically affected. Site 1 is the most ... Specifically, the two subunits come together to form a nucleotide-binding pocket; this pocket is targeted most often by ... "Inhibitor-bound structures of human pyruvate dehydrogenase kinase 4". Acta Crystallographica Section D. 67 (Pt 9): 763-73. doi: ...

*Multiple Epidermal Growth Factor-like Domains 8

Ccaat/Enhancer Binding Protein Vertebrate TATA binding protein factor CCAAT binding factors Activator-, mediator- and TBP- ... binding sites GATA binding factors Nuclear receptor subfamily 2 factors Octamer binding protein EGR/nerve growth factor induced ... More than one hundred transcription factor binding sites were predicted to be found in the megf8 promoter region through ... Calcium EGF-like domain: Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly ...

*IL18BP

Activation by an IFN-γ-induced complex of IFN regulatory factor 1 and CCAAT/enhancer binding protein β". Proc. Natl. Acad. Sci ... This protein binds to IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production. ... "Entrez Gene: IL18BP interleukin 18 binding protein". Dinarello CA (2002). "Novel targets for interleukin 18 binding protein". ... Interleukin-18-binding protein is a protein that in humans is encoded by the IL18BP gene. The protein encoded by this gene is ...

*CEBPA

CCAAT/enhancer-binding protein alpha is a transcription factor involved in the differentiation of certain Blood cells. For ... CCAAT/enhancer-binding protein alpha, the transcription factor that is encoded by CEBPA, is very important in the ... One category of mutations prevent CCAAT/enhancer-binding protein alpha DNA binding by altering its COOH-terminal basic leucine ... and transcription factor 1, TCF1, respectively) and of the hepatocyte growth factor/scatter factor gene (HGF)". Genomics. 13 (2 ...

*FOXI1

... regulation of human CYP3A4 basal expression by CCAAT enhancer-binding protein alpha and hepatocyte nuclear factor-3 gamma". ... "Identification of nine tissue-specific transcription factors of the hepatocyte nuclear factor 3/forkhead DNA-binding-domain ... "The forkhead transcription factor Foxi1 is a master regulator of vacuolar H-ATPase proton pump subunits in the inner ear, ... binding site specificity and DNA bending". The EMBO Journal. 13 (20): 5002-12. PMC 395442 . PMID 7957066. Larsson C, Hellqvist ...

*FOXA3

... regulation of human CYP3A4 basal expression by CCAAT enhancer-binding protein alpha and hepatocyte nuclear factor-3 gamma". Mol ... Hepatocyte nuclear factor 3-gamma (HNF-3G), also known as forkhead box protein A3 (FOXA3) or transcription factor 3G (TCF-3G) ... 2009). "Differential binding and co-binding pattern of FOXA1 and FOXA3 and their relation to H3K4me3 in HepG2 cells revealed by ... HNF-3G is a member of the forkheadclass of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional ...

*PIR (gene)

Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the ... "Entrez Gene: PIR pirin (iron-binding nuclear protein)". Dechend, R; Hirano F; Lehmann K; Heissmeyer V; Ansieau S; Wulczyn F G; ... 1999). "The Bcl-3 oncoprotein acts as a bridging factor between NF-kappaB/Rel and nuclear co-regulators". Oncogene. 18 (22): ... 2004). "Crystal structure of human pirin: an iron-binding nuclear protein and transcription cofactor". J. Biol. Chem. 279 (2): ...
Y-box binding protein 1 (YB-1) is encoded by the YBX1 gene in humans. It binds to splice sites in pre-mRNA, regulates splice site selection, and stabilizes cytoplasmic mRNA. YB-1 acts as a transcriptional regulator by: i) controlling the interaction between eukaryotic translation initiation factors and mRNA; and ii) binding to the Y-box motif found in the promoters of genes such as multidrug resistance 1 (MDR1) and HLA class II genes. YB-1 gene expression has been associated with lung cancer and the response to chemotherapy in patients with breast cancer. YB-1 is also known as nuclease sensitive element binding protein 1 (NSEP1), enhancer factor I subunit A, CCAAT-binding transcription factor I subunit A, DNA-binding protein B (DBPB), Y-box transcription factor, BP-8, CSDA2, CSDB1, and MDR-NF1.. ...
The genes coding for the A and B subunits of the transcription factor NF-Y are assigned by a combination of in situ hybridization and analysis of somatic cell hybrids and recombinant mouse strains. NF-YA is assigned to human chromosome 6p21 and to mouse chromosome 17. NF-YB is assigned to human chromosome 12 and to mouse chromosome 10.
TransAM NF-YA Kits are DNA-binding ELISAs that quantify activated NF-YA (nuclear factor Y, alpha) using a method that is faster and more sensitive than gelshift, without radioactivity and gels.
There is evidence that transcriptional control of topo IIα regulation is important in regulating gene expression at confluence (Isaacs et al., 1996), and under heat-shock conditions (Furukawa et al., 1998). A recent study indicated that transcriptional elements may regulate the cell cycle control of topo IIα expression (Falck et al., 1999). Furthermore, p53 may directly repress the promoter (Sandri et al., 1996b; Wang et al., 1997). The oncogenes ras andmyb have also been demonstrated to act through specific sequences within the topo IIα promoter. Both heat-shock and cell cycle regulation have been demonstrated to act through the ICB1 in the promoter (Falck et al., 1999), whereas confluence-induced down-regulation is regulated through the ICB2. This study confirms that, unlike with cell cycle regulation, the transcription factor NF-Y forms part of the ICB binding complex. There is an alteration in the intensity of the in vitro footprint seen at confluence, although this is not associated with ...
We previously identified proline-rich protein 11 (PRR11) as a novel cancer-related gene that is implicated in the regulation of cell cycle and tumorigenesis. Our recent study demonstrated that PRR11 and its adjacent gene, kinetochore associated 2 (SKA2), constitute a classic head-to-head gene pair that is coordinately regulated by nuclear factor Y (NF-Y). In the present study, we further show that the PRR11-SKA2 bidirectional transcription unit is an indirect target of the tumor suppressor p53. A luciferase reporter assay revealed that overexpression of wild type p53, but not mutant p53, significantly represses the basal activity and NF-Y mediated transactivation of the PRR11-SKA2 bidirectional promoter ...
Plasmid pTBRII / CEP-Zeo / Hygro from Dr. Bert Vogelsteins lab contains the insert TGF beta type II receptor and is published in Proc Natl Acad Sci U S A. 1998 Mar 3. 95(5):2412-6. This plasmid is available through Addgene.
Zwijsen A., Goumans M.J., Lawson K.A., Van Rooijen M.A., Mummery C.L.. Transforming growth factor beta (TGFbeta) regulates the cell cycle and extracellular matrix (ECM) deposition of many cells in vitro. We have analysed chimaeric mouse embryos generated from embryonic stem cells with abnormal receptor expression to study the effect of TGFbeta on these processes in vivo and the consequences for normal development. The binding receptor for TGFbeta, TbetaRII, is first detected in the embryo proper around day 8.5 in the heart. Ectopic expression of TbetaRII from the blastocyst stage onward resulted in an embryonic lethal around 9.5 dpc. Analysis of earlier stages revealed that the primitive streak of TbetaRII chimaeras failed to elongate. Furthermore, although cells passed through the streak and initially formed mesoderm, they tended to accumulate within the streak. These defects temporally and spatially paralleled the expression of the TGFbeta type I receptor, which is first expressed in the node ...
Cytokine signal transduction is essential for normal immune function and controls the quality of responses to a wide variety of microbial infections. Innate and adaptive host responses to virus infections are regulated by autocrine and paracrine cytokine signaling systems. For most cytokines, receptor binding triggers an intracellular signaling cascade involving one or more signal transducer and activator of transcription (STAT) proteins. Diverse cytokine and growth factor signaling pathways produce active STAT transcription factors that specify mRNA induction profiles (26). For example, the alpha and beta interferon (IFN-α/β) family is of primary importance for both innate and adaptive antiviral immunity (reviewed in references 1, 49, and 53). In the innate antiviral system, IFN-α/β initiates a receptor-mediated signaling system that produces an activated STAT1-STAT2-IRF9 heterotrimeric transcription complex known as ISGF3 (27). The ISGF3 complex translocates to the nucleus, where it can ...
Ubiquitous Illin Ness Pdf Download Ubiquitous Illin Ness Pdf Download. Hey Guys, heres my fancy new solo called "Ubiquitous Illin-ness" from the new tapspace book Violent Tenor Cream played with my new Vic Firth "Billy Club .. Landscape Performance Theory, an Introduction No matter how sophisticated you may be, .. NESS . do not have exact Informa tlon ag to the extent of the gamblin . ILLINI HALL May Made Begins Where Your Student Days Ended We are in harmony, .. What IKEA Tells Us About the Business Model of Law Practice . ness and was surprised at the .. Real-time spectrum analysis is used to predict and analyze . Ubiquitous (thank you, Dick .. A METASTABLE AUSTENITE WI!m PLANE STRESS FRACTURE TOUGH-NESS NEAR 500,000 . Download PDF to View . Ubiquitous Low-Cost Functionalized Multi-Walled Carbon .. Infrastructure Awareness . in ubiquitous computing systems in terms of accuracy and . ness model and a design space for Infrastructure Awareness.. The ubiquitous transcription factor NF-Y ...
configure --prefix=/usr --exec-prefix=/usr --bindir=/usr/bin --sbindir=/usr/sbin --sysconfdir=/etc --datadir=/usr/share --includedir=/usr/include --libdir=/usr/lib64 --libexecdir=/usr/libexec --sharedstatedir=/var/lib --mandir=/usr/share/man --infodir=/usr/share/info --build=x86_64-redhat-linux-gnu --host=x86_64-redhat-linux-gnu --target=x86_64-redhat-linux-gnu --program-prefix= --prefix=/opt/alt/php70 --exec-prefix=/opt/alt/php70 --bindir=/opt/alt/php70/usr/bin --sbindir=/opt/alt/php70/usr/sbin --sysconfdir=/opt/alt/php70/etc --datadir=/opt/alt/php70/usr/share --includedir=/opt/alt/php70/usr/include --libdir=/opt/alt/php70/usr/lib64 --libexecdir=/opt/alt/php70/usr/libexec --localstatedir=/var --with-curl=/opt/alt/curlssl/usr --sharedstatedir=/usr/com --mandir=/opt/alt/php70/usr/share/man --infodir=/opt/alt/php70/usr/share/info --cache-file=../config.cache --with-libdir=lib64 --with-config-file-path=/opt/alt/php70/etc ...
注意: PHP 5 では、foreachの実行開始時に内部配列ポインタは、 配列の先頭要素を指すように自動的にリセットされます。 このため、foreachループの前に reset()をコールする必要はありません。 PHP 5 では、foreach は内部の配列ポインタに依存するので、 ループ内で配列ポインタを変更すると予期せぬ振る舞いを引き起こします。 PHP 7 では、foreach は内部の配列ポインタを使わなくなりました。 ...
The biosynthesis of the beta-lactam antibiotic penicillin in the filamentous fungus Aspergillus nidulans is catalyzed by three enzymes that are encoded by the acvA, ipnA, and aatA genes. A variety of cis-acting DNA elements and regulatory factors form a complex regulatory network controlling these beta-lactam biosynthesis genes. Regulators involved include the CCAAT-binding complex AnCF and AnBH1. AnBH1 acts as a repressor of the penicillin biosynthesis gene aatA. Until now, however, little information has been available on the signal transduction cascades leading to the transcription factors. Here we show that inhibition of protein kinase C (Pkc) activity in A. nidulans led to cytoplasmic localization of an AnBH1-enhanced green fluorescent protein (EGFP) fusion protein. Computer analysis of the genome and screening of an A. nidulans gene library revealed that the fungus possesses two putative Pkc-encoding genes, which we designated pkcA and pkcB. Only PkcA showed all the characteristic features ...
Transcription is a process finely regulated by different transcription factors (TFs) which bind regulatory sequences present in gene promoters and allow the precise execution of gene expression programs. Misregulation of such process can lead to different pathologies, including development/differentiation defects, uncontrolled cell growth and cancer. For these reasons it is important to understand the molecular details of the interplay that occurs between different TFs to modulate gene expression. NF-Y, the heterotrimeric complex composed by NF-YA, NF-YB and NF-YC subunits, all required for DNA binding, recognizes the consensus sequence CCAAT, present in about 30% of eukaryotic promoters, at -60/-100 bp from the Transcription Start Site (TSS). One of the most important roles of NF-Y in transcription is to interact synergistically with other TFs to activate, or to repress, gene expression. In this study we focused on the relationship occurring between NF-Y and the TFs MAX, Myc and USF1, which ...
UCL Discovery is UCLs open access repository, showcasing and providing access to UCL research outputs from all UCL disciplines.
Expression of NFYA (CBF-B, HAP2, NF-YA) in breast tissue. Antibody staining with HPA050779 and CAB009250 in immunohistochemistry.
2,70 €). Mugav, kiire ja 100% ilmastikukindel. NB! Tasuta alates 49 € ostukorv. Kui sooritada ost tööpäeviti (E-R) enne kella 15:00 on eeldatav kättesaamisaeg järgmise päeval. Reedel peale 15:00, laupäeval, pühapäeval ja riiklikel pühadel sooritatud ostud toimetatakse kliendini ülejärgmisel tööpäeval.. Automaatide asukohad ja lahtioleku kellaajad. Automaatide täitmis kellaajad. ...
Некоторые проблемы возникают чаще других. Наиболее часто встречающиеся из них перечислены в разделе PHP FAQ этого руководства. ...
p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.,/p> ,p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.,/p> ,p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).,/p> ,p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x,sup>64,/sup> + x,sup>4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.,br /> ,strong>Cyclic redundancy and other checksums,/strong>,br /> ,a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993),/a>),/p> Checksum:i ...
Gentaur molecular products has all kinds of products like :search , Panomics \ C_EBPalpha _ C_EBPgamma EMSA Probe Set \ AY1274P for more molecular products just contact us
Peaks vist mainima, et laupäeva õhtul oli tormiline Liidu hooajalõpuüritus, kuid hommikuks olid kõik ikkagi vapralt stardis.. Pühapäeval puhusid ida ja kirde tuuled 1-4 ms ja kohtunikud nägid hea raja panemisega kurja vaeva. Päeva algatuseks jällegi Lenny võitis, kuid teises sõidus leidis stardis RockCity mingi imetuule ja kadus pikalt eest ära ning võitis teise sõidu, samas kui Lenny jäeti kolmandaks. regativõit jäi viimasele sõidule, kui Rock City võidab, saab ta ka Lennyst ette.. Viimases sõidus esimese ülemise märgi võttis liidrina Lenny, Freddy ja Rock City ees. Peale alumist märki olid kõik kolm paati koos ja tundus, et Rock City suudab vasakult hanitada. Lenny ja Rock City sõitsid koos vasakule, samas ...
Peaminister külastas reservväelaste õppust Okas 2017. Valitsus kutsus lisaõppekogunemise kokku kolmapäeval, 6.12, välja kutsuti reservväelased 669 ametikoha täitmiseks. Neljapäeval, 7.12 alanud õppus Okas 2017 kestab pühapäeva õhtuni. Tegu on teise korraga, kui Eesti oma reaalset kaitsevõimet sellisel kombel testib. Esimene lisaõppekogunemine toimus 2016. aasta detsembris, mil teenistusse kutsuti üle 300 reservväelase ja kaitseliitlase Põhja- ning Lõuna-Eestis. Video: Kaitsevägi ...
... Answer: PHP is pass by value, see the code below: |?php class Dog { public $name; public
TY - JOUR. T1 - Under pressure. T2 - Acute cardiac tamponade. AU - Chen, Leon. PY - 2019/5/1. Y1 - 2019/5/1. UR - http://www.scopus.com/inward/record.url?scp=85065026074&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=85065026074&partnerID=8YFLogxK. U2 - 10.1097/01.CCN.0000553086.79399.f0. DO - 10.1097/01.CCN.0000553086.79399.f0. M3 - Article. AN - SCOPUS:85065026074. VL - 14. SP - 35. EP - 37. JO - Nursing Critical Care. JF - Nursing Critical Care. SN - 1558-447X. IS - 3. ER - ...
I didnt realise, but ​Quercus is a PHP Implementation in Java, so its not a PHP 5.2 thing. If it was a PHP5.2 issue, Id expect many more broken sites, as every admin view would be fataling. Not sure it needs a backport, but doesnt do any harm either. Ill leave it up to nacin to decide what to do there ...
This article is basically helpfull in handling Registry Key through PHP code.; Author: amitjha1611; Updated: 10 Jul 2012; Section: PHP; Chapter: Web Development; Updated: 10 Jul 2012
13 milyon üzerinde projeye sahip dünyanın en büyük serbest çalışma pazarında Php output excel utf8 ile ilgili işler arayın ya da iş verin. Kaydolmak ve işlere teklif vermek ücretsizdir.
We have isolated a cDNA coding for a novel human protein that we called ICBP90, because it is an Inverted CCAAT box Binding Protein with a calculated size of 89,758 Da. Immunostaining experiments demonstrate that endogenous and overexpressed ICBP90 are located in the nucleus of HeLa and COS-1 cells, respectively. This is consistent with the presence of two potential nuclear localization signals found in the deduced ICBP90 amino acid sequence. No significant homology, except for the PHD finger (Fig. 3) ⇓ and the ubiquitin-like domain, was found with other proteins, some of which are known to be transcription factors. This suggests that ICBP90 may be a member of a new family of nuclear proteins with DNA-binding properties. Consistent with such an idea, recently, a mouse nuclear protein of 781 amino acids (Np95) was sequenced (39) . Np95 shows a 73.7% identity with ICBP90, which is not sufficient to conclude that Np95 is the mouse counterpart of ICBP90. Indeed, differences exist between these two ...
Epithelial ovarian cancer (EOC) makes up about probably the most gynecological malignancy-associated deaths in america. theres a positive correlation Mestranol between expression of EZH2 and NF-YA in EOCs. Large NF-YA expression predicts shorter general survival in EOC individuals Notably. The association of NF-YA using the promoter from the human being gene can be enhanced in […]. ...
etc/php.d/01-ioncube-loader.ini, /etc/php.d/20-bz2.ini, /etc/php.d/20-calendar.ini, /etc/php.d/20-ctype.ini, /etc/php.d/20-curl.ini, /etc/php.d/20-dom.ini, /etc/php.d/20-exif.ini, /etc/php.d/20-fileinfo.ini, /etc/php.d/20-ftp.ini, /etc/php.d/20-gd.ini, /etc/php.d/20-gettext.ini, /etc/php.d/20-gmp.ini, /etc/php.d/20-iconv.ini, /etc/php.d/20-imap.ini, /etc/php.d/20-mbstring.ini, /etc/php.d/20-mcrypt.ini, /etc/php.d/20-mysqlnd.ini, /etc/php.d/20-pdo.ini, /etc/php.d/20-phar.ini, /etc/php.d/20-posix.ini, /etc/php.d/20-shmop.ini, /etc/php.d/20-simplexml.ini, /etc/php.d/20-soap.ini, /etc/php.d/20-sockets.ini, /etc/php.d/20-sqlite3.ini, /etc/php.d/20-sysvmsg.ini, /etc/php.d/20-sysvsem.ini, /etc/php.d/20-sysvshm.ini, /etc/php.d/20-tidy.ini, /etc/php.d/20-tokenizer.ini, /etc/php.d/20-xml.ini, /etc/php.d/20-xmlwriter.ini, /etc/php.d/20-xsl.ini, /etc/php.d/20-zip.ini, /etc/php.d/30-mysql.ini, /etc/php.d/30-mysqli.ini, /etc/php.d/30-pdo_mysql.ini, /etc/php.d/30-pdo_sqlite.ini, /etc/php.d/30-wddx.ini, ...
Hi, Ive seen some real potential for using Dependency Injection, but all of the code I work with is PHP4 only. So, I thought Id see if I could make something work in PHP4. The PHP5 features used by dependency injectors seem to be: interfaces type hints in constructor signature
Hi, Ive seen some real potential for using Dependency Injection, but all of the code I work with is PHP4 only. So, I thought Id see if I could make something work in PHP4. The PHP5 features used by dependency injectors seem to be: interfaces type hints in constructor signature
Answer to the Race Conditions with Ajax and PHP Sessions, AJAX Locking is a PHP class which can be used to lock server side resources to prevent race conditions that may occur when two users want to access the same
Getting PHP Brilliance polished, indexed and proofed, helping web devs be awesome. | Check out Getting PHP Brilliance into print on Indiegogo.
Please note the internal behaviour of PHP that seems to do the reference assignment BEFORE actually copying the variable!!! Thus you get an array containing a (different) recursive array for the last testcase, instead of an array containing an empty array as you could expect ...
I just pruchased CS5 and am trying to view and modify a php file in Split view. The Split. Design and Love Codebuttonds are greted out. I tried
Faithful transcription initiation is critical for accurate gene expression, yet the mechanisms underlying specific transcription start site (TSS) selection in mammals remain unclear. Here, we show that the histone-fold domain protein NF-Y, a ubiquitously expressed transcription factor, controls the fidelity of transcription initiation at gene promoters in mouse embryonic stem cells. We report that NF-Y maintains the region upstream of TSSs in a nucleosome-depleted state while simultaneously protecting this accessible region against aberrant and/or ectopic transcription initiation. We find that loss of NF-Y binding in mammalian cells disrupts the promoter chromatin landscape, leading to nucleosomal encroachment over the canonical TSS. Importantly, this chromatin rearrangement is accompanied by upstream relocation of the transcription pre-initiation complex and ectopic transcription initiation. Further, this phenomenon generates aberrant extended transcripts that undergo translation, disrupting gene
Semua lirik lagu hasil pencarian lirik lagu besame muco/components/com_extcalendar/cal_popup.php/errors.php merupakan hak cipta atau hak milik dari penyanyi, pengarang, dan label musik yg bersangkutan. Jika Anda tertarik dengan lagu dari kata kunci besame muco/components/com_extcalendar/cal_popup.php/errors.php, Anda bisa beli kaset/CD originalnya atau menggunakan nada sambung pribadi (NSP) untuk mendukung artis penyanyi / band yang bersangkutan. Terima kasih sudah melakukan pencarian lirik lagu besame muco/components/com_extcalendar/cal_popup.php/errors.php.. ...
With the addition of type-checked function return values in PHP 7, we are one step closer to PHP being a gradually-typed language. This RFC proposes to close that gap with the addition of optional type-checked properties, by allowing the use of static type-hints for properties. Given that objects expose two types of public members, methods and properties, with optional type-checking for function arguments already present, and with the addition of type-checking for function return-values in PHP 7, the addition of type-checking for public properties is natural, and makes OOP in PHP fully gradually-typed. The significance of type-checked properties is a given, as demonstrated by its inclusion in Hack, as well as other recent scripting languages, including Typescript, Dart and ActionScript. The need for type-hinting is demonstrated by the widespread use of php-doc, and support for such type-hinting in modern PHP IDEs. The proposed syntax is compatible with that of Hack, and is a natural addition to ...
... PHP Fondamentaux : Créer des Applications Web Dynamiques | Formation professionnelle Demos. Créer une application web avec PHP 7
ကၽြန္ေတာ္အခု PHP သမားမ်ားအတြက္ အသံုးဝင္မယ္႔ စာအုပ္ေလးတစ္အုပ္ထပ္တင္ေပးလုိက္ပါတယ္။ အသံုးဝင္ပါတယ္။ ဖိုရမ္သမားမ်ားေတာ႔ သိၾကမွာပါ။ သူ႔အတြက္ Lessons ေလးေတြေတာ္ေတာ္ မ်ားမ်ားပါပါ တယ္။ ဖိုင္ဆိုဒ္ကေတာ႔ 14.87 MB ပဲရွိပါတယ္။ ေဆာင္ထားလုိက္ပါဗ်ာ ...
View and download MSF-USAs Annual Reports, Alert quarterly newsletter, briefing papers, transcripts, op-eds, research articles, and more.
php ?, ,?php /* Display navigation to next/previous pages when applicable */ ?, ,?php if ( $wp_query-,max_num_pages , 1 ) : ?, ,div id=nav-above class=navigation, ,div class=nav-previous,,?php next_posts_link( __( ,span class=meta-nav,←,/span, Older posts, twentyten ) ); ?,,/div, ,div class=nav-next,,?php previous_posts_link( __( Newer posts ,span class=meta-nav,→,/span,, twentyten ) ); ?,,/div, ,/div, ,?php endif; ?, ,?php /* If no posts to display, such as an empty archive page */ ?, ,?php if ( ! have_posts() ) : ?, ,div id=post-0 class=post error404 not-found, ,h1 class=entry-title,,?php _e( Not Found, twentyten ); ?,,/h1, ,div class=entry-content, ,p,,?php _e( Apologies, but no results were found for the requested archive. Perhaps searching will help find a related post., twentyten ); ?,,/p, ,?php get_search_form(); ?, ,/div, ,/div, ,?php endif; ?, ,?php /* Start the Loop. */ ?, ,?php while ( have_posts() ) : the_post(); ?, ,?php /* Display all posts. ...
example. exmp.php This class can be used to Measure the time PHP code takes to execute. It takes a string with PHP code and it executes the code repeatedly a given number times. The class can display a table showing the average time and the memory that the code took when it executed.
Offshore php programming company india offers custom php web programming services, outsource php programming solutions, professional advanced php programming.
We use cookies to enhance your experience on our website. By continuing to use our website, you are agreeing to our use of cookies. You can change your cookie settings at any time.Find out more ...
Ive got this piece of code that should work if session is set (check.php), but for some reason it doesnt, so can someone explain to me what Im I doing wrong here? In addition, if theres another way to call javascript code from PHP rather than echoing it, please let me know. input.php: |!DOCTYPE html PUBLIC -//W3C//DTD XHTML 1.0 Transitional//EN http://www.w3.org/TR/xhtml1/DTD/xhtml1-transitional.dtd| |html xmlns=http://www.w3.org/1999/xhtml| |head| |meta

Frontiers | Osa-miR169 Negatively Regulates Rice Immunity against the Blast Fungus Magnaporthe oryzae | Plant ScienceFrontiers | Osa-miR169 Negatively Regulates Rice Immunity against the Blast Fungus Magnaporthe oryzae | Plant Science

... negative regulator in rice immunity against the blast fungus Magnaporthe oryzae by repressing the expression of Nuclear Factor ... negative regulator in rice immunity against the blast fungus Magnaporthe oryzae by repressing the expression of Nuclear Factor ... 2015). A wheat CCAAT box-binding transcription factor increases the grain yield of wheat with less fertilizer input. Plant ... Nuclear transcription factor Y is a family of transcription factors specifically binding the CCAAT-box in the promoters of ...
more infohttps://www.frontiersin.org/articles/10.3389/fpls.2017.00002/full

A Transcription Factor Cascade Involving Fep1 and the CCAAT-Binding Factor Php4 Regulates Gene Expression in Response to Iron...A Transcription Factor Cascade Involving Fep1 and the CCAAT-Binding Factor Php4 Regulates Gene Expression in Response to Iron...

When we inserted multiple point mutations that mimic changes known to abolish binding of CCAAT-binding factor to CCAAT ... 201 harbors a copy of the sequence CCAAT that is identical to the binding site for the CCAAT-binding transcription factor (30 ... we inserted multiple point mutations that mimic changes known to abolish binding of the CCAAT-binding factor to CCAAT boxes (31 ... A Transcription Factor Cascade Involving Fep1 and the CCAAT-Binding Factor Php4 Regulates Gene Expression in Response to Iron ...
more infohttps://ec.asm.org/content/5/11/1866?ijkey=82c2f2c6d5c5b4f77813397262ffd97cd47c39ca&keytype2=tf_ipsecsha

nfix, nuclear factor I/X (CCAAT-binding transcription factor) - Creative Biogenenfix, nuclear factor I/X (CCAAT-binding transcription factor) - Creative Biogene

CCAAT-binding transcription factor); nuclear factor 1 X-type; NF1A; CCAAT box binding transcription factor; CCAAT-box-binding ... Nuclear factor 1 X type; Nuclear factor 1/X; Nuclear factor I/X; TGGCA binding protein; TGGCA-binding protein; nuclear factor I ... Nuclear factor 1 X-type is a protein that in humans is encoded by the NFIX gene. ... transcription factor; CTF; NF-I/X; NF1-X; NF1X; NFI X; NFI-X; NFI/X; NFIX_HUMAN; ...
more infohttps://www.creative-biogene.com/symbolsearch_nfix.html

nfyb - Nuclear Y/CCAAT-box binding factor B subunit NF-YB - Xenopus laevis (African clawed frog) - nfyb gene & proteinnfyb - Nuclear Y/CCAAT-box binding factor B subunit NF-YB - Xenopus laevis (African clawed frog) - nfyb gene & protein

Nuclear Y/CCAAT-box binding factor B subunit NF-YBImported. ,p>Information which has been imported from another database using ... tr,O73744,O73744_XENLA Nuclear Y/CCAAT-box binding factor B subunit NF-YB OS=Xenopus laevis OX=8355 GN=nfyb PE=2 SV=1 ...
more infohttp://www.uniprot.org/uniprot/O73744

WikiGenes - NFIC - nuclear factor I/C (CCAAT-binding...WikiGenes - NFIC - nuclear factor I/C (CCAAT-binding...

Two transcriptional activators, CCAAT-box-binding transcription factor and heat shock transcription factor, interact with a ... Nuclear factor I/CCAAT box transcription factor trans-activating domain is a negative sensor of cellular stress. Morel, Y., ... Promoter region of the human gene coding for beta-chain of C4b binding protein. Hepatocyte nuclear factor-3 and nuclear factor- ... Synonyms: CCAAT-box-binding transcription factor, CTF, CTF5, NF-I, NF-I/C, ... ...
more infohttps://www.wikigenes.org/e/gene/e/4782.html

Functional Cooperation of Simian Virus 40 Promoter Factor 1 and CCAAT/Enhancer-Binding Protein β and δ in Lipopolysaccharide...Functional Cooperation of Simian Virus 40 Promoter Factor 1 and CCAAT/Enhancer-Binding Protein β and δ in Lipopolysaccharide...

SF (steroidogenic factor-1), C/EBPβ (CCAAT/enhancer binding protein), and ubiquitous transcription factors NF1 (nuclear factor ... Functional Cooperation of Simian Virus 40 Promoter Factor 1 and CCAAT/Enhancer-Binding Protein β and δ in Lipopolysaccharide- ... Functional Cooperation of Simian Virus 40 Promoter Factor 1 and CCAAT/Enhancer-Binding Protein β and δ in Lipopolysaccharide- ... Functional Cooperation of Simian Virus 40 Promoter Factor 1 and CCAAT/Enhancer-Binding Protein β and δ in Lipopolysaccharide- ...
more infohttps://www.jimmunol.org/content/171/2/821?ijkey=e67031960b4926e9100297ec57fac1377935498a&keytype2=tf_ipsecsha

CERAMIDE, AN APOPTOTIC RHEOSTAT, INHIBITS CCAAT/ENHANCER BINDING PROTEIN-β AND NF-E2-RELATED FACTOR-2 ACTIVATION: THE ROLE IN...CERAMIDE, AN APOPTOTIC RHEOSTAT, INHIBITS CCAAT/ENHANCER BINDING PROTEIN-β AND NF-E2-RELATED FACTOR-2 ACTIVATION: THE ROLE IN...

CCAAT/enhancer binding protein-β (C/EBPβ) and NF-E2-related factor-2 (Nrf2) are both involved in the regulation of the genes ... CERAMIDE, AN APOPTOTIC RHEOSTAT, INHIBITS CCAAT/ENHANCER BINDING PROTEIN-β AND NF-E2-RELATED FACTOR-2 ACTIVATION: THE ROLE IN ... CERAMIDE, AN APOPTOTIC RHEOSTAT, INHIBITS CCAAT/ENHANCER BINDING PROTEIN-β AND NF-E2-RELATED FACTOR-2 ACTIVATION: THE ROLE IN ... CERAMIDE, AN APOPTOTIC RHEOSTAT, INHIBITS CCAAT/ENHANCER BINDING PROTEIN-β AND NF-E2-RELATED FACTOR-2 ACTIVATION: THE ROLE IN ...
more infohttp://dmd.aspetjournals.org/content/32/9/893

MEDLINE - Resultado p gina 1
	MEDLINE - Resultado p gina 1

0 (CCAAT-Binding Factor); 0 (Carrier Proteins); 0 (Fatty Acids); 0 (MIRN33 microRNA, human); 0 (MIRN33 microRNA, rat); 0 ( ... TXNIP deficiency leads to increased binding of nuclear factor Y (NFYA) to the sterol regulatory element binding protein 2 ( ... Fator de Liga o a CCAAT/gen tica. Fator de Liga o a CCAAT/metabolismo. Carnitina Aciltransferases/gen tica. Carnitina ... adenosine triphosphate binding cassette transporters A1, adenosine triphosphate binding cassette transporters G1, Neimann Pick ...
more infohttp://bases.bireme.br/cgi-bin/wxislind.exe/iah/online/?IsisScript=iah/iah.xis&nextAction=lnk&base=MEDLINE&lang=p&format=detailed.pft&indexSearch=EX&exprSearch=D08.811.913.050.350

Nfya - Nuclear transcription factor Y subunit alpha - Mus musculus (Mouse) - Nfya gene & proteinNfya - Nuclear transcription factor Y subunit alpha - Mus musculus (Mouse) - Nfya gene & protein

CCAAT-3 box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, ... Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5- ... DNA binding transcription factor activity Source: MGI ,p>Inferred from Direct Assay,/p> ,p>Used to indicate a direct assay for ... Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5-CCAAT-3 box ...
more infohttp://www.uniprot.org/uniprot/P23708

SWISSPROT: C5DCG7 LACTCSWISSPROT: C5DCG7 LACTC

DR InterPro; IPR005612; CCAAT-binding_factor. DR InterPro; IPR011501; Noc3_N. DR InterPro; IPR016903; Nucleolar_cplx-assoc_3. ...
more infohttp://pbil.univ-lyon1.fr/cgi-bin/acnuc-search-ac?query=C5DCG7&db=SWISSPROT

Schema of our method. We first calculate correlations b | Open-iSchema of our method. We first calculate correlations b | Open-i

CCAAT-Binding Factor/metabolism. *Consensus Sequence/physiology. *Disease Progression. *E2F4 Transcription Factor/metabolism ... Our analysis found that motifs bound by ELK1, E2F, NRF1 and NFY are potential regulatory motifs that positively correlate with ... Our analysis found that motifs bound by ELK1, E2F, NRF1 and NFY are potential regulatory motifs that positively correlate with ... little knowledge about regulatory mechanisms underling transcriptomic diversity.Our analysis found that motifs bound by ELK1, ...
more infohttps://openi.nlm.nih.gov/detailedresult.php?img=PMC2572072_1471-2105-9-404-1&req=4

CCAAT/enhancer binding protein zeta (mouse, aa620-633) Antibody (internal region) - Peptide-affinity purified goat antibody WB,...CCAAT/enhancer binding protein zeta (mouse, aa620-633) Antibody (internal region) - Peptide-affinity purified goat antibody WB,...

CCAAT/enhancer binding protein zeta (mouse, aa620-633) Antibody (internal region), Peptide-affinity purified goat antibody ... CCAAT-binding factor; CCAAT-box-binding transcription factor; CCAAT/enhancer binding protein alpha (C/EBP) related sequence 1; ... AF3887a: CCAAT/enhancer binding protein zeta (mouse) Antibody (C-Term). AF3888a: CCAAT/enhancer binding protein zeta (mouse, ... CCAAT/enhancer binding protein zeta (mouse, aa620-633) Antibody (internal region) is for research use only and not for use in ...
more infohttp://www.abgent.com/products/AF3888a-CCAATenhancer-binding-protein-zeta-mouse-aa620-633-Antibody-internal-region

Ybx1 Y box protein 1 [Mus musculus (house mouse)] - Gene - NCBIYbx1 Y box protein 1 [Mus musculus (house mouse)] - Gene - NCBI

CCAAT-binding transcription factor I subunit A. DNA-binding protein B. EFI-A. Y-box transcription factor. Y-box-binding protein ... Alternative forms of Y-box binding protein 1 and YB-1 mRNA. Lyabin DN, et al. PLoS One, 2014. PMID 25116735, Free PMC Article ... proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific ISO Inferred from Sequence Orthology ... Increased Expression of Y-Box-Binding Protein-1 in Hind-Limb Muscles During Regeneration from Ischemic Injury in Mice. Fuke M, ...
more infohttps://www.ncbi.nlm.nih.gov/gene/?term=22608

KAKEN - Research Projects | Analysis of genome maintenance system by the combination of proteomics and genetic approach ...KAKEN - Research Projects | Analysis of genome maintenance system by the combination of proteomics and genetic approach ...

Antagonistic controls of chromatin and mRNA start site selection by Tup family corepressors and the CCAAT-binding factor.2015. ... Journal Article] The proteasome factor Bag101 binds to Rad22 and suppresses homologous recombination.2014. *. Author(s). Saito ... Presentation] Tup family corepressor とCCAATーbinding factorによるクロマチン構造変化の拮抗的な制御がmRNA転写開始点を決定する2014. *. Author(s). 浅田隆大、竹俣直道、太田邦史、 ... Journal Article] Compensatory functions and interdependency
more infohttps://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-25281021/

REGULATOR: a database of metazoan transcription factors and maternal factors for developmental studiesREGULATOR: a database of metazoan transcription factors and maternal factors for developmental studies

CCAAT-binding transcription factor, subunit B. ENSCPOP00000010021. Pfam. PF02045. IPR001289. 263. 319. 5.20e-28. CCAAT-binding ... CCAAT-binding transcription factor, subunit B. ENSCPOP00000010021. SMART. SM00521. IPR001289. 261. 322. 7.80e-38. CCAAT-binding ... CCAAT-binding transcription factor, subunit B. ENSCPOP00000010021. PRINTS. PR00616. IPR001289. 296. 319. 1.10e-25. CCAAT- ... binding transcription factor, subunit B. ENSCPOP00000010021. ProSitePatterns. PS00686. IPR018362. 267. 287. -. CCAAT-binding ...
more infohttp://www.bioinformatics.org/regulator/page.php?act=detail&geneid=ENSCPOG00000011146

REGULATOR: a database of metazoan transcription factors and maternal factors for developmental studiesREGULATOR: a database of metazoan transcription factors and maternal factors for developmental studies

CCAAT-binding transcription factor, subunit B. ENSLACP00000017408. Pfam. PF02045. IPR001289. 254. 310. 5.00e-28. CCAAT-binding ... CCAAT-binding transcription factor, subunit B. ENSLACP00000017408. SMART. SM00521. IPR001289. 252. 313. 7.80e-38. CCAAT-binding ... CCAAT-binding transcription factor, subunit B. ENSLACP00000017408. PRINTS. PR00616. IPR001289. 287. 310. 1.10e-25. CCAAT- ... binding transcription factor, subunit B. ENSLACP00000017408. ProSitePatterns. PS00686. IPR018362. 258. 278. -. CCAAT-binding ...
more infohttp://www.bioinformatics.org/regulator/page.php?act=detail&geneid=ENSLACG00000015334

CCAAT/enhancer binding protein zeta - WikipediaCCAAT/enhancer binding protein zeta - Wikipedia

"A cloned human CCAAT-box-binding factor stimulates transcription from the human hsp70 promoter". Mol Cell Biol. 10 (12): 6709- ... CCAAT/enhancer-binding protein zeta is a protein that in humans is encoded by the CEBPZ gene. CCAAT/enhancer binding protein ... "Cloning and characterization of mouse CCAAT binding factor". Nucleic Acids Res. 24 (6): 1091-8. doi:10.1093/nar/24.6.1091. PMC ... "Physical interaction of tumour suppressor p53/p73 with CCAAT-binding transcription factor 2 (CTF2) and differential regulation ...
more infohttps://en.wikipedia.org/wiki/CCAAT/enhancer_binding_protein_zeta

A Phylogenetically Conserved Group of Nuclear Factor-Y Transcription Factors Interact to Control Nodulation in Legumes | Plant...A Phylogenetically Conserved Group of Nuclear Factor-Y Transcription Factors Interact to Control Nodulation in Legumes | Plant...

... strong binding to the third CCAAT box of the MtERN1 promoter). Binding of individual NF-Y subunits to CCAAT boxes has never ... 2014) The CCAAT box-binding transcription factor NF-YA1 controls rhizobial infection. J Exp Bot 65: 481-494. ... 2003) The B subunit of the CCAAT box binding transcription factor complex (CBF/NF-Y) is essential for early mouse development ... 1996) Determination of functional domains in the C subunit of the CCAAT-binding factor (CBF) necessary for formation of a CBF- ...
more infohttp://www.plantphysiol.org/content/169/4/2761?ijkey=72b0cd100629d71c4602a6485e38e6ba531d6738&keytype2=tf_ipsecsha

Mammalian Genes Are Transcribed with Widely Different Bursting Kinetics | ScienceMammalian Genes Are Transcribed with Widely Different Bursting Kinetics | Science

The molecular biology of the CCAAT-binding factor NF-Y. Gene 239, 15 (1999). doi:10.1016/S0378-1119(99)00368-6 pmid:10571030. ... S12). Indeed, using two CCAAT boxes instead of one, or choosing CCAAT boxes of higher affinity for NF-Y, increased the mean ... A and B) Cell lines carrying a single reporter gene containing either one (left panels) or two (right panels) CCAAT boxes with ... S3). Next, we generated a cell line containing a single transgene that specified a mRNA harboring 24 repeats of MS2-binding ...
more infohttp://science.sciencemag.org/content/332/6028/472?ijkey=b4664cd77a117db72650f5bf3ca0323fc1843e8b&keytype2=tf_ipsecsha

anti-NFYB antibody | Mouse anti-Human NFYB Monoclonal Antibody (Clone NFYBA7)-NP 006157.1anti-NFYB antibody | Mouse anti-Human NFYB Monoclonal Antibody (Clone NFYBA7)-NP 006157.1

nuclear transcription factor Y subunit beta; CAAT box DNA-binding protein subunit B; CCAAT-binding transcription factor subunit ... Cellular Component: nucleoplasm; CCAAT-binding factor complex; nucleus. Molecular Function: protein binding; DNA binding; ... forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a ... forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a ...
more infohttps://www.mybiosource.com/prods/Antibody/Monoclonal/NFYB/datasheet.php?products_id=120069

Candida albicans Hap43 Is a Repressor Induced under Low-Iron Conditions and Is Essential for Iron-Responsive Transcriptional...Candida albicans Hap43 Is a Repressor Induced under Low-Iron Conditions and Is Essential for Iron-Responsive Transcriptional...

A transcription factor cascade involving Fep1 and the CCAAT-binding factor Php4 regulates gene expression in response to iron ... Key function for the CCAAT-binding factor Php4 to regulate gene expression in response to iron deficiency in fission yeast. ... Novel regulatory function for the CCAAT-binding factor in Candida albicans. Eukaryot. Cell 4:1662-1676. ... The CCAAT-binding complex (Hap2/3/5) may take part in this complicated iron metabolism, together with Hap43, but its precise ...
more infohttps://ec.asm.org/content/10/2/207?ijkey=f50786678ff586b65f9f40fac66e24fe397f8eae&keytype2=tf_ipsecsha

Impaired Regulation of HLA-DR Expression in Human Immunodeficiency Virus-Infected Monocytes | Clinical and Vaccine ImmunologyImpaired Regulation of HLA-DR Expression in Human Immunodeficiency Virus-Infected Monocytes | Clinical and Vaccine Immunology

The molecular biology of the CCAAT-binding factor NF-Y. Gene 239:15-27. ... CCAAT box binding protein NF-Y facilitates in vivo recruitment of upstream DNA binding transcription factors. EMBO J. 13:4042- ... Rous sarcoma virus enhancer factor I is a ubiquitous CCAAT transcription factor highly related to CBF and NF-Y. J. Biol. Chem. ... Formation of a regulatory factor X/X2 box-binding protein/nuclear factor-Y multiprotein complex on the conserved regulatory ...
more infohttps://cvi.asm.org/content/9/4/739

Anti-YB1 antibody [EP2708Y] (ab76149) | AbcamAnti-YB1 antibody [EP2708Y] (ab76149) | Abcam

CCAAT binding transcription factor I subunit A antibody. *CCAAT-binding transcription factor I subunit A antibody ... Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to ... Binds to promoters that contain a Y-box (5-CTGATTGGCCAA-3), such as MDR1 and HLA class II genes. Promotes separation of DNA ...
more infohttp://www.abcam.com/yb1-antibody-ep2708y-ab76149.html

Anti-YB1 antibody [4F12] (ab219070) | AbcamAnti-YB1 antibody [4F12] (ab219070) | Abcam

CCAAT binding transcription factor I subunit A antibody. *CCAAT-binding transcription factor I subunit A antibody ... Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to ... Binds to promoters that contain a Y-box (5-CTGATTGGCCAA-3), such as MDR1 and HLA class II genes. Promotes separation of DNA ...
more infohttps://www.abcam.com/yb1-antibody-4f12-ab219070.html
  • In addition, several miRNA families act as resistance regulators to direct the silence of nucleotide-binding leucine-rich-repeat (NB-LRR) type disease resistance ( R ) genes in plants ( Baldrich and San Segundo, 2016 ). (frontiersin.org)
  • However, compared with the massive knowledge about the transcriptome, we have surprisingly little knowledge about regulatory mechanisms underling transcriptomic diversity.Our analysis found that motifs bound by ELK1, E2F, NRF1 and NFY are potential regulatory motifs that positively correlate with malignant progression of breast cancer.The results suggest that these 4 motifs are principal regulatory motifs driving malignant progression of breast cancer. (nih.gov)
  • Our analysis found that motifs bound by ELK1, E2F, NRF1 and NFY are potential regulatory motifs that positively correlate with malignant progression of breast cancer. (nih.gov)
  • By using PCR-mediated random binding selection process, researchers were able to show that the sequence "3' - (T/C)G ATTGG (T/C)(T/C)(A/G) - 5'" immediately flanking the ATTGG region (CCAAT in the complementary strand) was preferentially selected on the coding strand (opposite of the template strand). (wikipedia.org)
  • By gel shift assay and Western blotting, we found that the DNA binding complex and protein expression of C/EBPβ and δ were increased by LPS treatment, but these results were not found for Sp1. (jimmunol.org)
  • By site-directed mutagenesis, we found that disruption at both the Sp1 and C/EBP binding sites almost completely blocked the LPS response. (jimmunol.org)
  • Analysis of these two regions by gel shift assay suggested that Sp1 and C/EBPβ and δ were bound to these two regions, respectively. (jimmunol.org)