Cell Death: The termination of the cell's ability to carry out vital functions such as metabolism, growth, reproduction, responsiveness, and adaptability.Cause of Death: Factors which produce cessation of all vital bodily functions. They can be analyzed from an epidemiologic viewpoint.Death: Irreversible cessation of all bodily functions, manifested by absence of spontaneous breathing and total loss of cardiovascular and cerebral functions.Death, Sudden, Cardiac: Unexpected rapid natural death due to cardiovascular collapse within one hour of initial symptoms. It is usually caused by the worsening of existing heart diseases. The sudden onset of symptoms, such as CHEST PAIN and CARDIAC ARRHYTHMIAS, particularly VENTRICULAR TACHYCARDIA, can lead to the loss of consciousness and cardiac arrest followed by biological death. (from Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 7th ed., 2005)Brain Death: A state of prolonged irreversible cessation of all brain activity, including lower brain stem function with the complete absence of voluntary movements, responses to stimuli, brain stem reflexes, and spontaneous respirations. Reversible conditions which mimic this clinical state (e.g., sedative overdose, hypothermia, etc.) are excluded prior to making the determination of brain death. (From Adams et al., Principles of Neurology, 6th ed, pp348-9)Fetal Death: Death of the developing young in utero. BIRTH of a dead FETUS is STILLBIRTH.Attitude to Death: Conceptual response of the person to the various aspects of death, which are based on individual psychosocial and cultural experience.Caspases: A family of intracellular CYSTEINE ENDOPEPTIDASES that play a role in regulating INFLAMMATION and APOPTOSIS. They specifically cleave peptides at a CYSTEINE amino acid that follows an ASPARTIC ACID residue. Caspases are activated by proteolytic cleavage of a precursor form to yield large and small subunits that form the enzyme. Since the cleavage site within precursors matches the specificity of caspases, sequential activation of precursors by activated caspases can occur.Apoptosis: One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.Receptors, Death Domain: A family of cell surface receptors that signal via a conserved domain that extends into the cell CYTOPLASM. The conserved domain is referred to as a death domain due to the fact that many of these receptors are involved in signaling APOPTOSIS. Several DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS can bind to the death domains of the activated receptors and through a complex series of interactions activate apoptotic mediators such as CASPASES.Cell Survival: The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Mortality: All deaths reported in a given population.Autopsy: Postmortem examination of the body.Caspase 3: A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CASPASES such as CASPASE 9. Isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.Necrosis: The pathological process occurring in cells that are dying from irreparable injuries. It is caused by the progressive, uncontrolled action of degradative ENZYMES, leading to MITOCHONDRIAL SWELLING, nuclear flocculation, and cell lysis. It is distinct it from APOPTOSIS, which is a normal, regulated cellular process.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Proto-Oncogene Proteins c-bcl-2: Membrane proteins encoded by the BCL-2 GENES and serving as potent inhibitors of cell death by APOPTOSIS. The proteins are found on mitochondrial, microsomal, and NUCLEAR MEMBRANE sites within many cell types. Overexpression of bcl-2 proteins, due to a translocation of the gene, is associated with follicular lymphoma.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Signal Transduction: The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.Antigens, CD95: A tumor necrosis factor receptor subtype found in a variety of tissues and on activated LYMPHOCYTES. It has specificity for FAS LIGAND and plays a role in regulation of peripheral immune responses and APOPTOSIS. Multiple isoforms of the protein exist due to multiple ALTERNATIVE SPLICING. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM.Mitochondria: Semiautonomous, self-reproducing organelles that occur in the cytoplasm of all cells of most, but not all, eukaryotes. Each mitochondrion is surrounded by a double limiting membrane. The inner membrane is highly invaginated, and its projections are called cristae. Mitochondria are the sites of the reactions of oxidative phosphorylation, which result in the formation of ATP. They contain distinctive RIBOSOMES, transfer RNAs (RNA, TRANSFER); AMINO ACYL T RNA SYNTHETASES; and elongation and termination factors. Mitochondria depend upon genes within the nucleus of the cells in which they reside for many essential messenger RNAs (RNA, MESSENGER). Mitochondria are believed to have arisen from aerobic bacteria that established a symbiotic relationship with primitive protoeukaryotes. (King & Stansfield, A Dictionary of Genetics, 4th ed)Infant, Newborn: An infant during the first month after birth.DNA Fragmentation: Splitting the DNA into shorter pieces by endonucleolytic DNA CLEAVAGE at multiple sites. It includes the internucleosomal DNA fragmentation, which along with chromatin condensation, are considered to be the hallmarks of APOPTOSIS.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Survival Analysis: A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.Cell Line, Tumor: A cell line derived from cultured tumor cells.Caspase Inhibitors: Endogenous and exogenous compounds and that either inhibit CASPASES or prevent their activation.Cells, Cultured: Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Autophagy: The segregation and degradation of damaged or unwanted cytoplasmic constituents by autophagic vacuoles (cytolysosomes) composed of LYSOSOMES containing cellular components in the process of digestion; it plays an important role in BIOLOGICAL METAMORPHOSIS of amphibians, in the removal of bone by osteoclasts, and in the degradation of normal cell components in nutritional deficiency states.In Situ Nick-End Labeling: An in situ method for detecting areas of DNA which are nicked during APOPTOSIS. Terminal deoxynucleotidyl transferase is used to add labeled dUTP, in a template-independent manner, to the 3 prime OH ends of either single- or double-stranded DNA. The terminal deoxynucleotidyl transferase nick end labeling, or TUNEL, assay labels apoptosis on a single-cell level, making it more sensitive than agarose gel electrophoresis for analysis of DNA FRAGMENTATION.Caspase 8: A long pro-domain caspase that contains a death effector domain in its pro-domain region. Caspase 8 plays a role in APOPTOSIS by cleaving and activating EFFECTOR CASPASES. Activation of this enzyme can occur via the interaction of its N-terminal death effector domain with DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS.Infant Mortality: Postnatal deaths from BIRTH to 365 days after birth in a given population. Postneonatal mortality represents deaths between 28 days and 365 days after birth (as defined by National Center for Health Statistics). Neonatal mortality represents deaths from birth to 27 days after birth.Death Domain Receptor Signaling Adaptor Proteins: Intracellular signaling adaptor proteins that bind to the cytoplasmic death domain region found on DEATH DOMAIN RECEPTORS. Many of the proteins in this class take part in intracellular signaling from TUMOR NECROSIS FACTOR RECEPTORS.Cohort Studies: Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.BH3 Interacting Domain Death Agonist Protein: A member of the Bcl-2 protein family that reversibly binds MEMBRANES. It is a pro-apoptotic protein that is activated by caspase cleavage.Neurons: The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.United Statesbcl-2-Associated X Protein: A member of the Bcl-2 protein family and homologous partner of C-BCL-2 PROTO-ONCOGENE PROTEIN. It regulates the release of CYTOCHROME C and APOPTOSIS INDUCING FACTOR from the MITOCHONDRIA. Several isoforms of BCL2-associated X protein occur due to ALTERNATIVE SPLICING of the mRNA for this protein.Prognosis: A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.Survival Rate: The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.Reactive Oxygen Species: Molecules or ions formed by the incomplete one-electron reduction of oxygen. These reactive oxygen intermediates include SINGLET OXYGEN; SUPEROXIDES; PEROXIDES; HYDROXYL RADICAL; and HYPOCHLOROUS ACID. They contribute to the microbicidal activity of PHAGOCYTES, regulation of signal transduction and gene expression, and the oxidative damage to NUCLEIC ACIDS; PROTEINS; and LIPIDS.Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.Risk Assessment: The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)Age Factors: Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.Caspase 9: A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Caspase 9 is activated during cell stress by mitochondria-derived proapoptotic factors and by CARD SIGNALING ADAPTOR PROTEINS such as APOPTOTIC PROTEASE-ACTIVATING FACTOR 1. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES.Fas Ligand Protein: A transmembrane protein belonging to the tumor necrosis factor superfamily that was originally discovered on cells of the lymphoid-myeloid lineage, including activated T-LYMPHOCYTES and NATURAL KILLER CELLS. It plays an important role in immune homeostasis and cell-mediated toxicity by binding to the FAS RECEPTOR and triggering APOPTOSIS.Enzyme Activation: Conversion of an inactive form of an enzyme to one possessing metabolic activity. It includes 1, activation by ions (activators); 2, activation by cofactors (coenzymes); and 3, conversion of an enzyme precursor (proenzyme or zymogen) to an active enzyme.Incidence: The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.Cell Line: Established cell cultures that have the potential to propagate indefinitely.Amino Acid Chloromethyl Ketones: Inhibitors of SERINE ENDOPEPTIDASES and sulfhydryl group-containing enzymes. They act as alkylating agents and are known to interfere in the translation process.Homicide: The killing of one person by another.Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).Registries: The systems and processes involved in the establishment, support, management, and operation of registers, e.g., disease registers.Mice, Inbred C57BLSuicide: The act of killing oneself.Cytochromes c: Cytochromes of the c type that are found in eukaryotic MITOCHONDRIA. They serve as redox intermediates that accept electrons from MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX III and transfer them to MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX IV.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.Maternal Mortality: Maternal deaths resulting from complications of pregnancy and childbirth in a given population.Cysteine Proteinase Inhibitors: Exogenous and endogenous compounds which inhibit CYSTEINE ENDOPEPTIDASES.Kaplan-Meier Estimate: A nonparametric method of compiling LIFE TABLES or survival tables. It combines calculated probabilities of survival and estimates to allow for observations occurring beyond a measurement threshold, which are assumed to occur randomly. Time intervals are defined as ending each time an event occurs and are therefore unequal. (From Last, A Dictionary of Epidemiology, 1995)Poly(ADP-ribose) Polymerases: Enzymes that catalyze the transfer of multiple ADP-RIBOSE groups from nicotinamide-adenine dinucleotide (NAD) onto protein targets, thus building up a linear or branched homopolymer of repeating ADP-ribose units i.e., POLY ADENOSINE DIPHOSPHATE RIBOSE.bcl-X Protein: A member of the bcl-2 protein family that plays a role in the regulation of APOPTOSIS. Two major isoforms of the protein exist due to ALTERNATIVE SPLICING of the BCL2L1 mRNA and are referred to as Bcl-XS and Bcl-XL.bcl-Associated Death Protein: A pro-apoptotic protein and member of the Bcl-2 protein family that is regulated by PHOSPHORYLATION. Unphosphorylated Bad protein inhibits the activity of BCL-XL PROTEIN.Blotting, Western: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.Risk: The probability that an event will occur. It encompasses a variety of measures of the probability of a generally unfavorable outcome.Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.Wounds and Injuries: Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity.Mice, Knockout: Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.Programmed Cell Death 1 Receptor: An inhibitory T-lymphocyte receptor that has specificity for CD274 ANTIGEN and PROGRAMMED CELL DEATH 1 LIGAND 2 PROTEIN. Signaling by the receptor limits T cell proliferation and INTERFERON GAMMA synthesis. The receptor also may play an essential role in the regulatory pathway that induces PERIPHERAL TOLERANCE.Life Expectancy: Based on known statistical data, the number of years which any person of a given age may reasonably expected to live.Dose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Antineoplastic Agents: Substances that inhibit or prevent the proliferation of NEOPLASMS.Receptors, TNF-Related Apoptosis-Inducing Ligand: Tumor necrosis factor receptor family members that are widely expressed and play a role in regulation of peripheral immune responses and APOPTOSIS. The receptors are specific for TNF-RELATED APOPTOSIS-INDUCING LIGAND and signal via conserved death domains that associate with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM.TNF-Related Apoptosis-Inducing Ligand: A transmembrane-protein belonging to the TNF family of intercellular signaling proteins. It is a widely expressed ligand that activates APOPTOSIS by binding to TNF-RELATED APOPTOSIS-INDUCING LIGAND RECEPTORS. The membrane-bound form of the protein can be cleaved by specific CYSTEINE ENDOPEPTIDASES to form a soluble ligand form.Tumor Cells, Cultured: Cells grown in vitro from neoplastic tissue. If they can be established as a TUMOR CELL LINE, they can be propagated in cell culture indefinitely.Models, Biological: Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.Tumor Suppressor Protein p53: Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. A mutant or absent p53 protein has been found in LEUKEMIA; OSTEOSARCOMA; LUNG CANCER; and COLORECTAL CANCER.Enzyme Inhibitors: Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.Proto-Oncogene Proteins: Products of proto-oncogenes. Normally they do not have oncogenic or transforming properties, but are involved in the regulation or differentiation of cell growth. They often have protein kinase activity.Vital Statistics: Used for general articles concerning statistics of births, deaths, marriages, etc.Membrane Potential, Mitochondrial: The voltage difference, normally maintained at approximately -180mV, across the INNER MITOCHONDRIAL MEMBRANE, by a net movement of positive charge across the membrane. It is a major component of the PROTON MOTIVE FORCE in MITOCHONDRIA used to drive the synthesis of ATP.Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.Sex Factors: Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.Hospitalization: The confinement of a patient in a hospital.Tumor Necrosis Factor-alpha: Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.Multivariate Analysis: A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.Receptors, Tumor Necrosis Factor: Cell surface receptors that bind TUMOR NECROSIS FACTORS and trigger changes which influence the behavior of cells.Asphyxia: A pathological condition caused by lack of oxygen, manifested in impending or actual cessation of life.Transfection: The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.Jurkat Cells: A CELL LINE derived from human T-CELL LEUKEMIA and used to determine the mechanism of differential susceptibility to anti-cancer drugs and radiation.RNA, Small Interfering: Small double-stranded, non-protein coding RNAs (21-31 nucleotides) involved in GENE SILENCING functions, especially RNA INTERFERENCE (RNAi). Endogenously, siRNAs are generated from dsRNAs (RNA, DOUBLE-STRANDED) by the same ribonuclease, Dicer, that generates miRNAs (MICRORNAS). The perfect match of the siRNAs' antisense strand to their target RNAs mediates RNAi by siRNA-guided RNA cleavage. siRNAs fall into different classes including trans-acting siRNA (tasiRNA), repeat-associated RNA (rasiRNA), small-scan RNA (scnRNA), and Piwi protein-interacting RNA (piRNA) and have different specific gene silencing functions.Flow Cytometry: Technique using an instrument system for making, processing, and displaying one or more measurements on individual cells obtained from a cell suspension. Cells are usually stained with one or more fluorescent dyes specific to cell components of interest, e.g., DNA, and fluorescence of each cell is measured as it rapidly transverses the excitation beam (laser or mercury arc lamp). Fluorescence provides a quantitative measure of various biochemical and biophysical properties of the cell, as well as a basis for cell sorting. Other measurable optical parameters include light absorption and light scattering, the latter being applicable to the measurement of cell size, shape, density, granularity, and stain uptake.Cell Proliferation: All of the processes involved in increasing CELL NUMBER including CELL DIVISION.EnglandPopulation Surveillance: Ongoing scrutiny of a population (general population, study population, target population, etc.), generally using methods distinguished by their practicability, uniformity, and frequently their rapidity, rather than by complete accuracy.Hydrogen Peroxide: A strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.Terminal Care: Medical and nursing care of patients in the terminal stage of an illness.Bereavement: Refers to the whole process of grieving and mourning and is associated with a deep sense of loss and sadness.Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)Neuroprotective Agents: Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids.Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents.Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.Receptor-Interacting Protein Serine-Threonine Kinases: A family of serine-threonine kinases that plays a role in intracellular signal transduction by interacting with a variety of signaling adaptor proteins such as CRADD SIGNALING ADAPTOR PROTEIN; TNF RECEPTOR-ASSOCIATED FACTOR 2; and TNF RECEPTOR-ASSOCIATED DEATH DOMAIN PROTEIN. Although they were initially described as death domain-binding adaptor proteins, members of this family may contain other protein-binding domains such as those involving caspase activation and recruitment.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Mice, Transgenic: Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.Mortality, Premature: Deaths that occur before LIFE EXPECTANCY is reached within a given population.Rats, Sprague-Dawley: A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.Carrier Proteins: Transport proteins that carry specific substances in the blood or across cell membranes.DNA Damage: Injuries to DNA that introduce deviations from its normal, intact structure and which may, if left unrepaired, result in a MUTATION or a block of DNA REPLICATION. These deviations may be caused by physical or chemical agents and occur by natural or unnatural, introduced circumstances. They include the introduction of illegitimate bases during replication or by deamination or other modification of bases; the loss of a base from the DNA backbone leaving an abasic site; single-strand breaks; double strand breaks; and intrastrand (PYRIMIDINE DIMERS) or interstrand crosslinking. Damage can often be repaired (DNA REPAIR). If the damage is extensive, it can induce APOPTOSIS.Accidents, Traffic: Accidents on streets, roads, and highways involving drivers, passengers, pedestrians, or vehicles. Traffic accidents refer to AUTOMOBILES (passenger cars, buses, and trucks), BICYCLING, and MOTORCYCLES but not OFF-ROAD MOTOR VEHICLES; RAILROADS nor snowmobiles.Cytoprotection: The process by which chemical compounds provide protection to cells against harmful agents.Electrocardiography: Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.Membrane Glycoproteins: Glycoproteins found on the membrane or surface of cells.bcl-2 Homologous Antagonist-Killer Protein: A multi-domain mitochondrial membrane protein and member of the bcl-2 Protein family. Bak protein interacts with TUMOR SUPPRESSOR PROTEIN P53 and promotes APOPTOSIS.Annexin A5: A protein of the annexin family isolated from human PLACENTA and other tissues. It inhibits cytosolic PHOSPHOLIPASE A2, and displays anticoagulant activity.WalesCoronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.Up-Regulation: A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.Fatal Outcome: Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.RNA, Messenger: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.Cell Cycle: The complex series of phenomena, occurring between the end of one CELL DIVISION and the end of the next, by which cellular material is duplicated and then divided between two daughter cells. The cell cycle includes INTERPHASE, which includes G0 PHASE; G1 PHASE; S PHASE; and G2 PHASE, and CELL DIVISION PHASE.Membrane Proteins: Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.Wounds, Gunshot: Disruption of structural continuity of the body as a result of the discharge of firearms.TNF Receptor-Associated Death Domain Protein: A 34 kDa signal transducing adaptor protein that associates with TUMOR NECROSIS FACTOR RECEPTOR TYPE 1. It facilitates the recruitment of signaling proteins such as TNF RECEPTOR-ASSOCIATED FACTOR 2 and FAS ASSOCIATED DEATH DOMAIN PROTEIN to the receptor complex.Poisoning: A condition or physical state produced by the ingestion, injection, inhalation of or exposure to a deleterious agent.Gene Expression Regulation: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.JNK Mitogen-Activated Protein Kinases: A subgroup of mitogen-activated protein kinases that activate TRANSCRIPTION FACTOR AP-1 via the phosphorylation of C-JUN PROTEINS. They are components of intracellular signaling pathways that regulate CELL PROLIFERATION; APOPTOSIS; and CELL DIFFERENTIATION.Recurrence: The return of a sign, symptom, or disease after a remission.Cell Division: The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION.Phosphorylation: The introduction of a phosphoryl group into a compound through the formation of an ester bond between the compound and a phosphorus moiety.Inhibitor of Apoptosis Proteins: A conserved class of proteins that control APOPTOSIS in both VERTEBRATES and INVERTEBRATES. IAP proteins interact with and inhibit CASPASES, and they function as ANTI-APOPTOTIC PROTEINS. The protein class is defined by an approximately 80-amino acid motif called the baculoviral inhibitor of apoptosis repeat.Caspase 1: A long pro-domain caspase that has specificity for the precursor form of INTERLEUKIN-1BETA. It plays a role in INFLAMMATION by catalytically converting the inactive forms of CYTOKINES such as interleukin-1beta to their active, secreted form. Caspase 1 is referred as interleukin-1beta converting enzyme and is frequently abbreviated ICE.HeLa Cells: The first continuously cultured human malignant CELL LINE, derived from the cervical carcinoma of Henrietta Lacks. These cells are used for VIRUS CULTIVATION and antitumor drug screening assays.Biological Markers: Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.Severity of Illness Index: Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.Down-Regulation: A negative regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.Caspase 2: A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Activation of this enzyme can occur via the interaction of its caspase recruitment domain with CARD SIGNALING ADAPTOR PROTEINS. Caspase 2 plays a role in APOPTOSIS by cleaving and activating effector pro-caspases. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.Heart Diseases: Pathological conditions involving the HEART including its structural and functional abnormalities.Reverse Transcriptase Polymerase Chain Reaction: A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.Forensic Pathology: The application of pathology to questions of law.Logistic Models: Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.Stillbirth: The event that a FETUS is born dead or stillborn.Disease Progression: The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.Lung Neoplasms: Tumors or cancer of the LUNG.Cell Nucleus: Within a eukaryotic cell, a membrane-limited body which contains chromosomes and one or more nucleoli (CELL NUCLEOLUS). The nuclear membrane consists of a double unit-type membrane which is perforated by a number of pores; the outermost membrane is continuous with the ENDOPLASMIC RETICULUM. A cell may contain more than one nucleus. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)Brain: The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.Animals, Newborn: Refers to animals in the period of time just after birth.Caspase 7: A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CASPASES such as CASPASE 3 and CASPASE 10. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.Tissue and Organ Procurement: The administrative procedures involved with acquiring TISSUES or organs for TRANSPLANTATION through various programs, systems, or organizations. These procedures include obtaining consent from TISSUE DONORS and arranging for transportation of donated tissues and organs, after TISSUE HARVESTING, to HOSPITALS for processing and transplantation.Propidium: Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits.Cysteine Endopeptidases: ENDOPEPTIDASES which have a cysteine involved in the catalytic process. This group of enzymes is inactivated by CYSTEINE PROTEINASE INHIBITORS such as CYSTATINS and SULFHYDRYL REAGENTS.RNA Interference: A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-INDUCED SILENCING COMPLEX. DNA METHYLATION may also be triggered during this process.Phenotype: The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.NF-kappa B: Ubiquitous, inducible, nuclear transcriptional activator that binds to enhancer elements in many different cell types and is activated by pathogenic stimuli. The NF-kappa B complex is a heterodimer composed of two DNA-binding subunits: NF-kappa B1 and relA.Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).Great BritainCell Count: The number of CELLS of a specific kind, usually measured per unit volume or area of sample.Epidemiologic Methods: Research techniques that focus on study designs and data gathering methods in human and animal populations.Odds Ratio: The ratio of two odds. The exposure-odds ratio for case control data is the ratio of the odds in favor of exposure among cases to the odds in favor of exposure among noncases. The disease-odds ratio for a cohort or cross section is the ratio of the odds in favor of disease among the exposed to the odds in favor of disease among the unexposed. The prevalence-odds ratio refers to an odds ratio derived cross-sectionally from studies of prevalent cases.Gene Expression: The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.Proteins: Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.Apoptotic Protease-Activating Factor 1: A CARD signaling adaptor protein that plays a role in the mitochondria-stimulated apoptosis (APOPTOSIS, INTRINSIC PATHWAY). It binds to CYTOCHROME C in the CYTOSOL to form an APOPTOSOMAL PROTEIN COMPLEX and activates INITIATOR CASPASES such as CASPASE 9.Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.Regression Analysis: Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.Breast Neoplasms: Tumors or cancer of the human BREAST.Staurosporine: An indolocarbazole that is a potent PROTEIN KINASE C inhibitor which enhances cAMP-mediated responses in human neuroblastoma cells. (Biochem Biophys Res Commun 1995;214(3):1114-20)Cytochrome c Group: A group of cytochromes with covalent thioether linkages between either or both of the vinyl side chains of protoheme and the protein. (Enzyme Nomenclature, 1992, p539)Smoking: Inhaling and exhaling the smoke of burning TOBACCO.Genes, bcl-2: The B-cell leukemia/lymphoma-2 genes, responsible for blocking apoptosis in normal cells, and associated with follicular lymphoma when overexpressed. Overexpression results from the t(14;18) translocation. The human c-bcl-2 gene is located at 18q24 on the long arm of chromosome 18.Neurotoxins: Toxic substances from microorganisms, plants or animals that interfere with the functions of the nervous system. Most venoms contain neurotoxic substances. Myotoxins are included in this concept.Microscopy, Fluorescence: Microscopy of specimens stained with fluorescent dye (usually fluorescein isothiocyanate) or of naturally fluorescent materials, which emit light when exposed to ultraviolet or blue light. Immunofluorescence microscopy utilizes antibodies that are labeled with fluorescent dye.Acute Disease: Disease having a short and relatively severe course.Protein-Serine-Threonine Kinases: A group of enzymes that catalyzes the phosphorylation of serine or threonine residues in proteins, with ATP or other nucleotides as phosphate donors.Life Tables: Summarizing techniques used to describe the pattern of mortality and survival in populations. These methods can be applied to the study not only of death, but also of any defined endpoint such as the onset of disease or the occurrence of disease complications.JapanCalcium: A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.Recombinant Proteins: Proteins prepared by recombinant DNA technology.Comorbidity: The presence of co-existing or additional diseases with reference to an initial diagnosis or with reference to the index condition that is the subject of study. Comorbidity may affect the ability of affected individuals to function and also their survival; it may be used as a prognostic indicator for length of hospital stay, cost factors, and outcome or survival.Calpain: Cysteine proteinase found in many tissues. Hydrolyzes a variety of endogenous proteins including NEUROPEPTIDES; CYTOSKELETAL PROTEINS; proteins from SMOOTH MUSCLE; CARDIAC MUSCLE; liver; platelets; and erythrocytes. Two subclasses having high and low calcium sensitivity are known. Removes Z-discs and M-lines from myofibrils. Activates phosphorylase kinase and cyclic nucleotide-independent protein kinase. This enzyme was formerly listed as EC 3.4.22.4.Adaptor Proteins, Signal Transducing: A broad category of carrier proteins that play a role in SIGNAL TRANSDUCTION. They generally contain several modular domains, each of which having its own binding activity, and act by forming complexes with other intracellular-signaling molecules. Signal-transducing adaptor proteins lack enzyme activity, however their activity can be modulated by other signal-transducing enzymesDNA-Binding Proteins: Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases.Receptors, Tumor Necrosis Factor, Type I: A tumor necrosis factor receptor subtype that has specificity for TUMOR NECROSIS FACTOR ALPHA and LYMPHOTOXIN ALPHA. It is constitutively expressed in most tissues and is a key mediator of tumor necrosis factor signaling in the vast majority of cells. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM.Cerebrovascular Disorders: A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.Antioxidants: Naturally occurring or synthetic substances that inhibit or retard the oxidation of a substance to which it is added. They counteract the harmful and damaging effects of oxidation in animal tissues.Tissue Donors: Individuals supplying living tissue, organs, cells, blood or blood components for transfer or transplantation to histocompatible recipients.Child Mortality: Number of deaths of children between one year of age to 12 years of age in a given population.SwedenChi-Square Distribution: A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.Fibroblasts: Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.Microtubule-Associated Proteins: High molecular weight proteins found in the MICROTUBULES of the cytoskeletal system. Under certain conditions they are required for TUBULIN assembly into the microtubules and stabilize the assembled microtubules.Grief: Normal, appropriate sorrowful response to an immediate cause. It is self-limiting and gradually subsides within a reasonable time.Perinatal Mortality: Deaths occurring from the 28th week of GESTATION to the 28th day after birth in a given population.Proto-Oncogene Proteins c-akt: A protein-serine-threonine kinase that is activated by PHOSPHORYLATION in response to GROWTH FACTORS or INSULIN. It plays a major role in cell metabolism, growth, and survival as a core component of SIGNAL TRANSDUCTION. Three isoforms have been described in mammalian cells.

Avoidable mortality in Europe 1955-1994: a plea for prevention. (1/6129)

OBJECTIVE: To analyse trends of avoidable mortality in Europe, emphasising causes of death amenable to primary prevention through reduction of exposures, secondary prevention through early detection and treatment, and tertiary prevention through improved treatment and medical care. DESIGN: Descriptive study of mortality from avoidable causes for the years 1955 through 1994, for ages 5-64 at time of death. Using the World Health Organisation Mortality Database, five year death rates were standardised to the world population. SETTING: 21 countries of Europe in four regions (northern, central, and southern Europe, Nordic countries). PARTICIPANTS: All causes of deaths for men and women, aged 5-64, at time of death. MAIN RESULTS: Between 1955-59 and 1990-94, the reduction in mortality was somewhat greater for avoidable causes than for all causes: 45.8% v 45.1% (women) and 39.3% v 32.6% among men. Reductions in mortality were greater for causes amenable to improved medical care: 77.9% among women and 76.3% among men. The smallest reduction in mortality was seen in women for causes amenable to secondary prevention (11.0%), and in men for causes amendable to primary prevention including tobacco related conditions (16.6%). From a geographical point of view, there were slight differences in trends between European regions, but overall the patterns were similar. CONCLUSIONS: The greatest reduction of avoidable mortality in Europe from 1955-94 came from causes amenable to improved treatment and medical care for both sexes. Further reductions of avoidable mortality can be achieved through implementation of primary and secondary prevention activities, such as tobacco control, reduction of occupational exposures, and universal access to breast and cervical cancer screening programmes.  (+info)

Comparative total mortality in 25 years in Italian and Greek middle aged rural men. (2/6129)

STUDY OBJECTIVE: Mortality over 25 years has been low in the Italian and very low in the Greek cohorts of the Seven Countries Study; factors responsible for this particularity were studied in detail. PARTICIPANTS AND SETTINGS: 1712 Italian and 1215 Greek men, aged 40-59 years, cohorts of the Seven Countries Study, representing over 95% of the populations in designated rural areas. DESIGN: Entry (1960-61) data included age, systolic blood pressure (SBP), smoking habits, total serum cholesterol, body mass index (BMI), arm circumference, vital capacity (VC), and forced expiratory volume in 3/4 seconds (FEV); the same data were obtained 10 years later. Multivariate Cox analysis was performed with all causes death in 25 years as end point. MAIN RESULTS: Italian men had higher entry levels of SBP, arm circumference, BMI, and VC; Greek men had higher cholesterol levels, smoking habits, and FEV. Mortality of Italian men was higher throughout; at 25 years cumulative mortality was 48.3% and 35.3% respectively. Coronary heart disease and stroke mortality increased fivefold in Italy and 10-fold in Greece between years 10 and 25. The only risk factor with a significantly higher contribution to mortality in Italian men was cholesterol. However, differences in entry SBP (higher in Italy) and FEV (higher in Greece) accounted for, according to the Lee method, 75% of the differential mortality between the two populations. At 10 years increases in SBP, cholesterol, BMI, and decreases in smoking habits, VC, FEV, and arm circumference had occurred (deltas). SBP increased more and FEV and VC decreased more in Italy than in Greece. Deltas, fed stepwise in the original model for the prediction of 10 to 25 years mortality, were significant for SBP, smoking, arm circumference, and VC in Greece, and for SBP and VC in Italy. CONCLUSION: Higher mortality in Italian men is related to stronger positive effects of entry SBP and weaker negative (protective) effects of FEV; in addition 10 year increases in SBP are higher and 10 year decreases in FEV are larger in Italy. Unaccounted factors, however, related to, for example, differences in the diet, may also have contributed to the differential mortality of these two Mediterranean populations.  (+info)

Respiratory symptoms and long-term risk of death from cardiovascular disease, cancer and other causes in Swedish men. (3/6129)

BACKGROUND: Depressed respiratory function and respiratory symptoms are associated with impaired survival. The present study was undertaken to assess the relation between respiratory symptoms and mortality from cardiovascular causes, cancer and all causes in a large population of middle-aged men. METHODS: Prospective population study of 6442 men aged 51-59 at baseline, free of clinical angina pectoris and prior myocardial infarction. RESULTS: During 16 years there were 1804 deaths (786 from cardiovascular disease, 608 from cancer, 103 from pulmonary disease and 307 from any other cause). Men with effort-related breathlessness had increased risk of dying from all of the examined diseases. After adjustment for age, smoking habit and other risk factors, the relative risk (RR) associated with breathlessness of dying from coronary disease was 1.43 (95% CI : 1.16-1.77), from stroke 1.77 (95% CI: 1.07-2.93), from any cardiovascular disease 1.48 (95% CI : 1.24-1.76), cancer 1.36 (95% CI : 1.11-1.67) and from any cause 1.62 (95% CI: 1.44-1.81). An independent effect of breathlessness on cardiovascular death, cancer death and mortality from all causes was found in life-time non-smokers, and also if men with chest pain not considered to be angina were excluded. An independent effect was also found if all deaths during the first half of the follow-up were excluded. Men with cough and phlegm, without breathlessness, also had an elevated risk of dying from cardiovascular disease and cancer, but after adjustment for smoking and other risk factors this was no longer significant. However, a slightly elevated independent risk of dying from any cause was found (RR = 1.18 [95% CI: 1.02-1.36]). CONCLUSION: A positive response to a simple question about effort related breathlessness predicted subsequent mortality from several causes during a follow-up period of 16 years, independently of smoking and other risk factors.  (+info)

Water traffic accidents, drowning and alcohol in Finland, 1969-1995. (4/6129)

OBJECTIVE: To examine age- and sex-specific mortality rates and trends in water traffic accidents (WTA), and their association with alcohol, in Finland. MATERIALS AND METHODS: National mortality and population data from Finland, 1969-1995, are used to analyse rates and trends. The mortality rates are calculated on the basis of population, per 100000 inhabitants in each age group (<1, 1-4, 5-14, 15-24, 25-44, 45-64, > or = 65), and analysed by sex and age. The Poisson regression model and chi2 test for trend (EGRET and StatXact softwares) are used to analyse time trends. RESULTS: From 1969 through 1995 there were 3473 (2.7/100000/year; M:F= 20.4:1) WTA-related deaths among Finns of all ages. In 94.7% of the cases the cause of death was drowning. Alcohol intoxication was a contributing cause of death in 63.0% of the fatalities. During the study period the overall WTA mortality rates declined significantly (-4% per year; P < 0.001). This decline was observed in all age groups except > or = 65 year olds. The overall mortality rates in WTA associated with alcohol intoxication (1987-1995) also declined significantly (-6%; P = 0.01). CONCLUSIONS: In Finland, mortality rates in WTA are exceptionally high. Despite a marked decline in most age groups, the high mortality in WTA nevertheless remains a preventable cause of death. Preventive countermeasures targeted specifically to adult males, to the reduction of alcohol consumption in aquatic settings and to the use of personal safety devices should receive priority.  (+info)

A method for calculating age-weighted death proportions for comparison purposes. (5/6129)

OBJECTIVE: To introduce a method for calculating age-weighted death proportions (wDP) for comparison purposes. MATERIALS AND METHODS: A methodological study using secondary data from the municipality of Sao Paulo, Brazil (1980-1994) was carried out. First, deaths are weighted in terms of years of potential life lost before the age of 100 years. Then, in order to eliminate distortion of comparisons among proportions of years of potential life lost before the age of 100 years (pYPLL-100), the denominator is set to that of a standard age distribution of deaths for all causes. Conventional death proportions (DP), pYPLL-100, and wDP were calculated. RESULTS: Populations in which deaths from a particular cause occur at older ages exhibit lower wDP than those in which deaths occur at younger ages. The sum of all cause-specific wDP equals one only when the test population has exactly the same age distribution of deaths for all causes as that of the standard population. CONCLUSION: Age-weighted death proportions improve the information given by conventional DP, and are strongly recommended for comparison purposes.  (+info)

The meaning and use of the cumulative rate of potential life lost. (6/6129)

BACKGROUND: The 'years of potential life lost' (YPLL) is a public health measure in widespread use. However, the index does not apply to the comparisons between different populations or across different time periods. It also has the limit of being cross-sectional in nature, quantifying current burden but not future impact on society. METHODS: A new years-lost index is proposed-the 'cumulative rate of potential life lost' (CRPLL). It is a simple combination of the 'cumulative rate' (CR) and the YPLL. Vital statistics in Taiwan are used for demonstration and comparison of the new index with existing health-status measures. RESULTS: The CRPLL serves the purpose of between-group comparison. It can also be considered a projection of future impact, under the assumption that the age-specific mortality rates in the current year prevail. For a rare cause of death, it can be interpreted as the expected years (days) of potential life lost during a subject's lifetime. CONCLUSIONS: The CRPLL has several desirable properties, rendering it a promising alternative for quantifying health status.  (+info)

Toxic oil syndrome mortality: the first 13 years. (7/6129)

BACKGROUND: The toxic oil syndrome (TOS) epidemic that occurred in Spain in the spring of 1981 caused approximately 20000 cases of a new illness. Overall mortality and mortality by cause in this cohort through 1994 are described for the first time in this report. METHODS: We contacted, via mail or telephone, almost every living member of the cohort and family members of those who were known to have died in order to identify all deaths from 1 May 1981 through 31 December 1994. Cause of death data were collected from death certificates and underlying causes of death were coded using the International Classification of Diseases, 9th Revision. RESULTS: We identified 1663 deaths between 1 May 1981 and 31 December 1994 among 19 754 TOS cohort members, for a crude mortality rate of 8.4%. Mortality was highest during 1981, with a standardized mortality ratio (SMR) of 4.92 (95% confidence interval [CI]: 4.39-5.50) compared with the Spanish population as a whole. The highest SMR, (20.41, 95% CI: 15.97-25.71) was seen among women aged 20-39 years during the period from 1 May 1981 through 31 December 1982. Women <40 years old, who were affected by TOS , were at greater risk for death in most time periods than their unaffected peers, while older women and men were not. Over the follow-up period, mortality of the cohort was less than expected when compared with mortality of the general Spanish population, or with mortality of the population of the 14 provinces where the epidemic occurred. We also found that, except for deaths attributed to external causes including TOS and deaths due to pulmonary hypertension, all causes of death were decreased in TOS patients compared to the Spanish population. The most frequent underlying causes of death were TOS, 350 (21.1%); circulatory disorders, 536 (32.3%); and malignancies, 310 (18.7%). CONCLUSIONS: We conclude that while on average people affected by toxic oil syndrome are not at greater risk for death over the 13-year study period than any of the comparison groups, women <40 years old were at greater risk of death.  (+info)

Failing firefighters: a survey of causes of death and ill-health retirement in serving firefighters in Strathclyde, Scotland from 1985-94. (8/6129)

During the decade beginning 1 January 1985, 887 full-time firefighters, all male, left the service of Strathclyde Fire Brigade (SFB). There were 17 deaths--compared to 64.4 expected in the Scottish male population aged 15-54 years--giving a standardized mortality ratio (SMR) of 26, and 488 ill-health retirements (IHR). None of the deaths was attributable to service, the major causes being: myocardial infarction--five, (expected = 17.3; SMR = 29); cancers--three (colon, kidney and lung) (expected = 13.6; SMR = 22); road traffic accidents--two (expected = 4.17; SMR = 48) and suicide--two (expected = 4.9; SMR = 41). Amalgamating the deaths and IHRs showed that the six most common reasons for IHR were musculoskeletal (n = 202, 40%), ocular (n = 61, 12.1%), 'others' (n = 58, 11.5%), injuries (n = 50, 9.9%), heart disease (n = 48, 9.5%) and mental disorders (n = 45, 8.9%). Over 300 IHRs (over 60%) occurred after 20 or more years service. When the IHRs were subdivided into two quinquennia, there were 203 and 302 in each period. Mean length of service during each quinquennium was 19.4 vs. 21.3 years (p = 0.003) and median length was 21 years in both periods; interquartile range was 12-26 years in the first and 17-27 years in the second period (p = 0.002), but when further broken down into diagnostic categories, the differences were not statistically significant, with the exception of means of IHRs attributed to mental disorders (14.5 vs. 19 years, p = 0.03).  (+info)

Suggested Citation: Garko, M.G. (2013, October). Fiber - Part IV: Dietary and functional fiber and the immediate cause of the obesity epidemic. Health and Wellness Monthly. Retrieved (insert month, day, year), from www.letstalknutrition.com. Fiber - Part IV: Dietary and Functional Fiber and the Immediate Cause of the Obesity Epidemic Michael Garko, Ph.D. Producer […]
Potential Years of Life Lost (PYLL) is given for each year from 1980 to 2012. Three separate PYLL indicators are included: PYLL65 up to age 65, PYLL70 up to age 70 and PYLL70_rate, which is the number of potential years of life lost up to age 70 per 100,000 population aged under 70. For the purposes of the last of these indicators, the WHO European Standard Population (see Appendix) has been used. For 2009 and 2010, year of registration data are used; for all previous years, statistics are based on year of occurrence. A total of 74 causes of death categories are reported. These are ordered according to the Eurostat 65 Cause of Death shortlist, along with 9 additional national categories. The classification system used for data up to and including 2006 is ICD9. From 2007, ICD10 is used. Caution should be exercised in comparing data up to 2006 with data from 2007 onwards. ...
OBJECTIVES: Most analyses of asthma mortality in the United States have relied solely on underlying cause-of-death data, which may underestimate the magnitude of asthma-related mortality. We used multiple cause-of-death data to examine asthma-related mortality trends in the United States. METHODS: Data were selected from the United States Multiple Cause-of-Death Files ...
The analysis highlighted, as expected, high values of the ASPR for all the AIDS-defining conditions, which are rare among non-AIDS/HIV deaths. The condition most strongly associated with AIDS was toxoplasmosis (ASPR = 4,167; 95% CI: 583.4-29,769.1), in addition to other AIDS-defining infections such as criptococcosis (ASPR = 480.4; 95% CI: 192.1-1,201.2), other mycobacterial infections (other than tuberculosis and Hansen disease; ASPR = 330.3; 95% CI: 157.4-693) and pneumocystosis (ASPR = 208.1; 95% CI: 129.6-334.2). Besides infectious diseases, a very strong association was observed for Kaposi sarcoma (KS; ASPR = 298.9; 95% CI: 162.4-550.1) and -although with lower ASPR values compared to KS- diffuse and other/unspecified non-Hodgkin lymphoma (NHL; ASPR = 14.1 and 6.5, respectively), cachexia (ASPR = 3.9), and cervical cancer (ASPR = 2.8).. Among non AIDS-defining diseases, the infectious conditions with the highest ASPR were leishmaniasis (ASPR = 188; 95% CI: 39.5-894.1) and chronic viral ...
Lovely Muthiah, Jovita Dsouza, Abbasi Kanwal and Biji Thomas George-Temperomandibular Disorder Related Causes - A Short Communication
Part two in a series, sharing information you can use to empower yourself when dealing with health professionals who seem more interested in the speed of their diagnosis than on figuring out whats really going on, today a differential diagnosis algorithm devised for docs to use to rule out other medical causes of psychosis in kids. The…
via Change.org My partner Scott and I should have been sharing our son Edward Gilis first birthday last month. But instead of having that exciting first year to celebrate and many more to look forward to, we had just 9 precious days to spend with our beautiful son. Edward was cruelly taken from us as a result of…
Poisoning from prescription or illicit drugs is one of the leading causes of death from unintentional injury in the United States. The Centers for Disease Control and Prevention (CDC) analyzed data from 1999 to 2004 and found that the annual deaths from poisoning had increased 62.5 percent.
Andrew Pickerings Constructing Quarks claims that the scientific communitys evaluation of atomic parity violation experiments was determined by career considerations, and not the quality of the experimental observations. This essay argues that scientists had good evidential reasons to accept atomic parity violation as a strong confirmation of the Weinberg-Salam Standard Model of weak interactions.
How long is modern medicine going to go on casting a blind eye to nutritional medicine before millions of lives are lost? The hope of a vaccine looms, but is months away. Even with a 100% vaccination rate and 100% vaccine effectiveness, by my calculations it is likely such a vaccine would generate more hospitalizations and deaths than the disease itself because of the weak immune status of the individual.. Risk of infection is low and death is nil.. Among healthy adults the risk for infection is very, very small, and the risk for death is almost nil - - in China 3000 (avoidable) deaths in 58 million or 5 in 100,000). Infection and mortality rates are much lower in the U.S. Most of those deaths were among fragile, unhealthy adults over age 70.. The number of reported cases of infection may be far lower than what actually occurs because some patients may never come in contact with the medical care system and recover at home, some only experiencing a mild fever or never even exhibiting symptoms ...
Data & statistics on Standardised mortality rate from external causes per 100000: Standardized death rates from external cause injury and poison, all ages, per 100 000, EU-15, Standardized death rates from external cause injury and poison, all ages, per 100 000, EU-12, Trends in mortality from external causes among males...
Provides a guide to data on deaths resulting from drug use. It is designed to assist researchers and analysts in utilising Causes of Death data produced by the Australian Bureau of Statistics (ABS). Issues discussed include ABS terminology and classifications used to code drug deaths. ...
View Notes - List_of_Rates from PB HLTH 140 at Berkeley. SUMMARY OF RATES DEATH RATES Crude Death Rate Toma Deaths Death Rate 0 POP Itim x 1000 Crude Death Rate for Cause Total Tuberculosis
Each year, ∼100 countries worldwide report data from their vital registration systems on causes of death in their populations 4. The quality and coverage of these statistics vary enormously, yet they are of major relevance for public health. Vital registration systems that capture all deaths in a population, and include a medical certificate completed by a qualified practitioner as to the medical conditions preceding death, are the "gold standard" for assessing causes of death. Yet, in many countries, these systems either fail to capture all deaths, fail to provide a specific clinical diagnosis as to the underlying cause of death, or provide an incorrect cause. This is true even for developed countries. Thus, many deaths coded to heart failure or ventricular dysrythmias, for example, in countries such as Japan, Spain or France would, in the USA, UK or Australia, be more likely to be recognised as due to ischaemic heart disease 1. The implications of such miscoding can be substantial. For ...
Stretch marks can form as a result of weight gain, muscles and pregnancy. Watch this video to find out various causes of stretch marks.
The analysis of the demographic dynamism of the population and its evolution over time rests on the implementation of demographic statistical operations whose main update sources are the Civil Registers, a census-type administrative register ...
In a nation that is quick to tout its health care system as the best in the world, troubling signs have emerged that should give pause to those who craft public policy.
Causes Allergy Articles: Get information on Causes Allergy. Read articles and learn about all the facts related to Causes Allergy from our health website Onlymyhealth.com.
A Detailed Insight on Causes and Symptoms of Piles. Are you suffering from bleeding around your anus for some days? Dont get any tension.
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SNP rs10911021 at the glutamate-ammonia ligase (GLUL) locus has been associated with an increased risk of coronary heart disease in type 2 diabetes. The effect of this SNP on mortality was investigated among 1,242 White subjects with type 2 diabetes from the Joslin Kidney Study (JKS, n=416) and the Gargano Mortality Study (n=826). During a mean follow-up of 12.8 ± 5.8 and 7.5 ± 2.2 years, respectively, a total of 215 and 164 deaths were observed in the two studies. In both cohorts, all-cause mortality rate significantly increased with the number of rs10911021 risk alleles, with allelic HRs of 1.32 (95% CI 1.07-1.64, p=0.01), 1.30 (1.10-1.69, p=0.04), and 1.32 (1.12-1.55, p=0.0011) in the JKS, GMS, and the two studies combined, respectively. These associations were not affected by adjustment for possible confounders. In the JKS, for which data on causes of death were available, the HRs for cardiovascular mortality was 1.51 (1.12-2.04; p=0.0077) as opposed to 1.15 (0.84-1.55; p=0.39) for ...
In 2014, the ABS implemented Iris, a new automated coding software product for assisting in the processing of cause of death data. With the introduction of new coding software, the ABS has also implemented the most up to date version of the ICD-10, and improved a number of coding practices to realign with international best practice. As part of this, the process for coding perinatal deaths was changed with no underlying cause of death being derived for neonatal deaths in the 2013 dataset. An expanded range of neonatal death data has been made available in the 2013 Perinatal deaths datacube, to assist data users in the short term while a solution to this issue is sought in the medium term. These updates and improvements have resulted in changes to output for the 2013 dataset. It is advised that data users refer to: ...
Using SWAT officers to storm into homes to execute search warrants has led time and again to avoidable deaths, gruesome injuries and costly legal settlements.
Our plan is to work with researchers at varous institutions of higher learning in the developed, developing and under-developed world who may wish to join forces with our network to reduce the burden of escalating avoidable death and poverty due to special pathogens. Please fill free fill our membership forms in the website so we can work together in this mision. Read more... ...
An anonymous reader writes: According to new research from the CDC, 9.8% of deaths in working-age adults (22-64 years old) in the U.S. from 2006 to 2010 were attributable to excessive drinking. This makes excessive drinking the fourth leading cause of preventable death in the U.S. The study inclu...
Notes: The colours correspond to the main categories of diseases red=of circulatory system, yellow= neoplasms, blue=of respiratory system, green=of nervous system, dark grey=external causes and light grey=other diseases.. Percentage of deaths due to diseases of the circulatory system is similar for men and women over 80 years old (about 43%), while the percentages of men is more than twofold in the age-group 50-64 years (27% versus 12%). On the other hand, neoplasm percentages are higher for women than men, especially in the age groups 50-64 years (60% versus 43%) and 35-49 years (54% versus 40%). External causes of death are much more common for men (54%) aged 35-49 years than for women (23 ...
• In 2013, reduced kidney function was associated with 4% of deaths worldwide, or 2.2 million deaths. • More than half of these deaths were cardiovascular deaths.
I went all through the summer with it hoarse and scratchy, into the fall, and I went to see him again about five weeks ago. No improvement. The doctor literally had no suggestions for me. I was pretty deflated. I sat in his exam chair, I slumped over, put my head down, and wept a bit. This second appointment was before my heart came back, and I remember thinking how is it possible for a person to get MS, a disease that isnt well understood and certainly has no medical clarity on cause, treatment or cure, then get Afib, a second disease that has no medical clarity on cause, treatment or cure, and now a third? I just thought about how many times Ive gone to a doctor in the past 7-10 years with no good news. Sure some were great. I have well documented the CCSVI results Ive had and some others, but my god. Id lost most of the use of my legs, my heart was working at 65% of normal efficiency and I was at risk for stroke and/or heart attack, and now my voice is going with no explanation? How do I ...
Causes of Cardiac arrest including triggers, hidden medical causes of Cardiac arrest, risk factors, and what causes Cardiac arrest.
Tiredness is a complex medical issue as there are so many possible causes. Here are a few possible medical causes but consider non-medical causes too.
Sweating is one of the ways our body keeps our temperature normal, but when people are unwell they can have episodes of increased sweating. When this is severe it can be very uncomfortable and affect activities like sleeping. There are different causes, including certain medicines. Your doctor will be able to advise you on the best treatment, depending on the cause. There are also things you can do to help:. ...
The legal definition of Act of God is An event which is caused solely by the effect of nature or natural causes and without any interference by humans whatsoever.
Countries with highest or lowest death rates in selected causes of death Test your knowledge on this geography quiz to see how you do and compare your score to others. Quiz by MrMischief
19 July 2002 Doubled death rate follows rise in pig diseasePOST-WEANING mortality rates in the UK have doubled over the past year, reflecting the dramatic
Death rate for people in the U.S. has risen. Common causes are are cardiovascular disease, stroke and diabetes, all of which are linked to obesity.
IntroductionKey issues and gapsWho is at risk and whyThe level of need in the populationCurrent services in relation to needService users and carers opinion
Downloadable! A general finding in the empirical literature on charitable giving is that among older individuals, both the probability of giving and the conditional amount of donations decrease with age, ceteris paribus. In this paper, we use data on giving by alumni at an anonymous university to investigate end-of-life giving patterns. Our main finding is that taking into account the approach of death substantially changes the age-giving profile for the elderly?in one segment of the age distribution, the independent effect of an increase in age on giving actually changes from negative to positive. We examine how the decline in giving as death approaches varies with the length of time that a given condition is likely to bring about death, and the individual?s age when he died. We find that for individuals who died from conditions that bring about death fairly quickly, there is little decline in giving as death approaches compared to those who died from other causes. Further, the decline in giving as
(Mods, please feel free to move if you think Ive miscategorized this...) 1.When did you first remembering acknowledging your own mortality? 2.How does...
Seniors who said they felt three or more years younger than their actual age experienced a lower death rate over the course of eight years than people who either felt their full age or a little older.
He had just returned from holiday in the United States but neither MI6 nor GCHQ have wanted to make public what the codebreaker was involved in at the time of his death ...
Define proportional mortality. proportional mortality synonyms, proportional mortality pronunciation, proportional mortality translation, English dictionary definition of proportional mortality. adj. 1. Forming a relationship with other parts or quantities; being in proportion. 2. Properly related in size, degree, or other measurable...
Background: Incomplete information on death certificates makes recorded cause-of-death data less useful for public health monitoring and planning. Certifying physicians sometimes list only the mode of death without indicating the underlying disease or diseases that led to the death. Inconsistent cause-of-death assignment among cardiovascular causes of death is of particular concern. This can prevent valid epidemiologic comparisons across countries and over time. Methods: We propose that coarsened exact matching be used to infer the underlying causes of death where only the mode of death is known. We focus on the case of heart failure in US, Mexican, and Brazilian death records.Results Redistribution algorithms derived using this method assign the largest proportion of heart failure deaths to ischemic heart disease in all three countries (53%, 26%, and 22% respectively), with larger proportions assigned to hypertensive heart disease and diabetes in Mexico and Brazil (16% and 23% vs. 7% for ...
Health Reports, volume 23, number 3. Cause-specific mortality by education in Canada: A 16-year follow-up study. Table 4 Age-standardized mortality rates per 100,000 person-years at risk for selected causes of death, by educational attainment, age group and sex, cohort members aged 25 or older at baseline, Canada 1991 to 2006
With the news of Scott Weilands death surfacing late last night, not much was known at the time. The former Stone Temple Pilots and Velvet Revolver frontman was found dead on his tour bus last night. Weiland was on tour in Minnesota with his solo band The Wildabouts when he was found.. Weiland has had well-documented substance abuse issues, previously kicking a serious heroin addiction. TMZ obtained audio of the emergency call and dispatchers said the singer was not breathing and his immediate cause of death was cardiac arrest. The underlying cause of death has not been determined yet.. TMZ claims that multiple sources in the music industry told them that friends were worrying in the days leading up to his death that he was deep into crack cocaine use and might have died of an overdose. Weilands wife refutes those reports saying he has been sober off drugs for years, that his band has a pact to do no drugs on tour and he had only been drinking socially in recent years.. Update: According to ...
There is a large margin of error in death statistics. Mortality statistics for cerebrovascular disease show, however, the well-known rise in frequency with age, the higher frequency in men than women which is likely to affect all countries in the coming years, and the greater involvement of nonwhite Americans and Japanese than of white Americans and Japanese Americans. I believe that incidence figures, when they become available in future years, will confirm these findings. Environmental factors, such as a "water factor," also relate to cerebrovascular death rates. Possibly the biggest factor in the medical environment, causing artificial swings in both mortality and incidence figures, will be shown to be the changing diagnostic habits of physicians.. From the viewpoint of etiology, the coexistence of hypertension and cerebrovascular disease dominates the epidemiological picture. The geographic distribution of cerebrovascular mortality in the U.S.A., and the higher mortality in Negroes and in ...
First, of all, it isnt a count of deaths each year from flu. We dont know how many people die of seasonal influenza each year because there is no list we can use to count them. Why not just use the death certificate information? You can see what a death certificate looks like here. The Cause of Death section has two parts. Part I. asks for the immediate cause of death (first line) and any underlying conditions that brought it about (up to four subsequent lines). The underlying causes are the "due to" components. Suppose someone dies of gram negative sepsis, a total systemic failure usually caused by a bacterial infection. The lines below the immediate cause are supposed to be the links in the causal chain leading to the sepsis. Bacterial pneumonia would be a typical cause of sepsis, so we have an immediate cause of death of gram negative sepsis due to bacterial pneumonia. Secondary infection by bacteria is a common complication of a respiratory viral infection, so the next line might be viral ...
BACKGROUND: The extent to which adult height, a biomarker of the interplay of genetic endowment and early-life experiences, is related to risk of chronic diseases in adulthood is uncertain. METHODS: We calculated hazard ratios (HRs) for height, assessed in increments of 6.5 cm, using individual-participant data on 174374 deaths or major non-fatal vascular outcomes recorded among 1085949 people in 121 prospective studies. RESULTS: For people born between 1900 and 1960, mean adult height increased 0.5-1 cm with each successive decade of birth. After adjustment for age, sex, smoking and year of birth, HRs per 6.5 cm greater height were 0.97 (95% confidence interval: 0.96-0.99) for death from any cause, 0.94 (0.93-0.96) for death from vascular causes, 1.04 (1.03-1.06) for death from cancer and 0.92 (0.90-0.94) for death from other causes. Height was negatively associated with death from coronary disease, stroke subtypes, heart failure, stomach and oral cancers, chronic obstructive pulmonary disease, mental
Cause-specific mortality among neurosurgeons. Lollis SS1, Valdes PA, Li Z, Ball PA, Roberts DW. Author information J Neurosurg. 2010 Sep;113(3):474-8. doi: 10.3171/2010.1.JNS091740. Abstract OBJECT: The authors sought to determine a cause-specific mortality profile for US neurosurgeons during the period 1979-2005. METHODS: Neurosurgeons who died during the study period were identified from the Physician Master File…
IHME research used de-identified death records from the National Center for Health Statistics (NCHS) and population counts from the U.S. Census Bureau, NCHS, and the Human Mortality Database and small area estimation models in order to estimate county-level mortality rates from all cardiovascular diseases (CVD), including ischemic heart disease, cerebrovascular disease, ischemic stroke, and other types. This dataset provides estimates for age-standardized mortality rates by CVD type and sex at the county level for each state, the District of Columbia, and the United States as a whole for 1980-2014, as well as the changes in rates for each location during this period. Also included are data on the 10 counties with the highest and lowest mortality rates for each CVD type in 2014 and the top 10 causes of death by CVD type for each county. Study results were published in JAMA in May 2017 in "Trends and patterns of geographic variations in cardiovascular mortality among US counties, ...
What are some medical causes for dog aggression? Often, what looks like aggression is simply a dog in pain whose threshold for aggression has lowered.
Data & statistics on Heart Disease Death Rate by Race in Iowa: Heart Disease Death Rate by Race in Iowa, 2001-2005, Age-Adjusted Mortality: Heart Disease (Quad Cities Area by Race; 2001-2003 Deaths per 100,000 Population), Heart Disease Mortality Rates: 2000-2006...
London, United Kingdom, Mar 7 - British pop icon George Michael who was found dead at his home on Christmas Day, died of natural causes, a coroner announce - Kenya breaking news | Kenya news today | Capitalfm.co.ke
LONDON • British pop icon George Michael who was found dead at his home on Christmas Day, died of natural causes, a coroner announced.. Read more at straitstimes.com.
The prevalence of class III obesity (body mass index [BMI]≥40 kg/m2) has increased dramatically in several countries and currently affects 6% of adults in the US, with uncertain impact on the risks of illness and death. Using data from a large pooled study, we evaluated the risk of death, overall and due to a wide range of causes, and years of life expectancy lost associated with class III obesity.In a pooled analysis of 20 prospective studies from the United States, Sweden, and Australia, we estimated sex- and age-adjusted total and cause-specific mortality rates (deaths per 100,000 persons per year) and multivariable-adjusted hazard ratios for adults, aged 19-83 y at baseline, classified as obese class III (BMI 40.0-59.9 kg/m2) compared with those classified as normal weight (BMI 18.5-24.9 kg/m2). Participants reporting ever smoking cigarettes or a history of chronic disease (heart disease, cancer, stroke, or emphysema) on baseline questionnaires were excluded. Among 9,564 class III obesity ...
Dietary fiber intake has been positively linked to the prevention of four of the ten leading causes of death among adults in the United States. The Centers for Disease Control and Prevention (CDC) listed the leading causes of death in 2010 as 1) heart disease, 2) cancer, 3) chronic lower respiratory disease, 4) stroke, 5) accidents, 6) Alzheimers disease, 7) diabetes, 8) nephritis (kidney disease), 9) influenza/pneumonia, and 10) suicides (Murphy, Xu, & Kochanek, 2013). Heart disease was responsible for a proportional mortality ratio (PMR) of 27% of deaths. Stroke was fourth on the list with 6% of deaths (CDC, 2012). Diabetes is also a very serious condition that was responsible for approximately 69,000 deaths in 2010 (Murphy et al., 2013). The serious consequences of the aforementioned conditions have led researchers to study a variety of prevention strategies, including dietary fiber intake.
Overview. SEER is an authoritative source of information on cancer incidence and survival in the United States. SEER currently collects and publishes cancer incidence and survival data from population-based cancer registries covering approximately 28 percent of the U.S. population.. Read Full Overview. ...
GREENSBORO, N.C. - Police say a man who was found dead over the weekend on the side of a Greensboro roadway died of natural causes. Officers responded shortly after 8:45 p.m. Saturday to a report of a man lying on the side of the road at the Creek Ridge overpass at U.S. 220.
OBJECTIVE--To determine the effects of lowering cholesterol concentrations on total and cause specific mortality in randomised primary prevention trials. DESIGN--Qualitative (meta-analytic) evaluation of total mortality from coronary heart disease, cancer, and causes not related to illness in six primary prevention trials of cholesterol reduction (mean duration of treatment 4.8 years). PATIENTS--24,847 Male participants; mean age 47.5 years. MAIN OUTCOME MEASURES--Total and cause specific mortalities. RESULTS--Follow up periods totalled 119,000 person years, during which 1147 deaths occurred. Mortality from coronary heart disease tended to be lower in men receiving interventions to reduce cholesterol concentrations compared with mortality in control subjects (p = 0.06), although total mortality was not affected by treatment. No consistent relation was found between reduction of cholesterol concentrations and mortality from cancer, but there was a significant increase in deaths not related to ...
Free, official coding info for 2020 ICD-10-CM V80.919 - includes detailed rules, notes, synonyms, ICD-9-CM conversion, index and annotation crosswalks, DRG grouping and more.
A brand new dual stage loader designed to unload overloaded iron ore carts at a BHP mine in Western Australia is wrecked during transport, this happen...
The TAC Medical Excess may apply to these services Policy The TAC will pay the reasonable cost of human donor tissue required for transport accident injuries. Transport Accident Act 1986 reference: s.3 medical service and s.60 Guideline Payment will be made in accordance with the Department of Health and Ageings
A new report on obesity from the Organisation for Economic Co-operation and Development (OECD) makes for grim reading; it details that even just being overweight will slash almost 3 years from life expectancy, on average, with this figure rising to 4 years in the United States (Medscape October 11, 2019), confirming my analysis from 2 decades ago:. Lifetime risk of developing coronary heart disease Sanchez-Delgadoa, Heinz Liechtia Lancet, Volume 353, Issue 9156, Pages 924 - 925, 13 March 1999. We compared caloric intake with life expectancy in the 20 most developed countries and found that, an ingestion of 280 kcal less every day corresponds to 25 months longer lifespan and vice versa.. When we compared prospectively the pulse×mass index with the calculations of cardiovascular disease risk factors according to the Framingham Heart Study, the correlation was highly significant (r=0•94; ...
mportance The literature focuses on mortality among children younger than 5 years. Comparable information on nonfatal health outcomes among these children and the fatal and nonfatal burden of diseases and injuries among older children and adolescents is scarce. Objective To determine levels and trends in the fatal and nonfatal burden of diseases and injuries among younger children (aged ,5 years), older children (aged 5-9 years), and adolescents (aged 10-19 years) between 1990 and 2013 in 188 countries from the Global Burden of Disease (GBD) 2013 study. Evidence Review Data from vital registration, verbal autopsy studies, maternal and child death surveillance, and other sources covering 14 244 site-years (ie, years of cause of death data by geography) from 1980 through 2013 were used to estimate cause-specific mortality. Data from 35 620 epidemiological sources were used to estimate the prevalence of the diseases and sequelae in the GBD 2013 study. Cause-specific mortality for most causes was ...
Increasing levels of YLLs might reflect outcomes from conditions that required high levels of care but for which effective treatments remain elusive, potentially lifting costs to health systems. The Global Burden of Disease 2016 Study provided an assessment of cause-specific mortality for 264 causes in 195 locations from 1980 to 2016.. Deaths from noncommunicable diseases represented 72.3% of all deaths in 2016, with 19.3% of deaths in that year occurring from CMNN diseases.. In 2016, the three leading global causes of death in children under five were lower respiratory infections, neonatal preterm birth complications and neonatal encephalopathy because of birth asphyxia and trauma.. Between 1990 and 2016, a shift toward deaths at older ages occurred, with a 178% increase in deaths in ages 90 and 94 years and a 210% increase in deaths older than age 95 years.. The 10 leading causes by rates of age-standardized YLL declined from 2006 to 2016; the median annualized rate of change for all other ...
BackgroundSocioeconomic inequalities in death rates from all causes combined widened from 1960 until 1990 in the U.S., largely because cardiovascular death rates decreased more slowly in lower than in higher socioeconomic groups. However, no studies have examined trends in inequalities using recent US national data.Methodology/Principal FindingsWe calculated annual age-standardized death rates from 1993-2001 for 25-64 year old non-Hispanic whites and blacks by level of education for all causes and for the seven most common causes of death using death certificate information from 43 states and Washington, D.C. Regression analysis was used to estimate annual percent change. The inequalities in all cause death rates between Americans with less than high school education and college graduates increased rapidly from 1993 to 2001 due to both significant decreases in mortality from all causes, heart disease, cancer, stroke, and other conditions in the most educated and lack of change or increases among the
Chronic lower respiratory disease, including chronic bronchitis, asthma and emphysema, killed 160,201 people in 2017. In 2005, longtime "Tonight Show" host Johnny Carson died from respiratory failure caused by emphysema.
Loving the retro color palette and excellent type styling in this infographic on causes of and treatments of excess perspiration. #excesssweat #infographic #sweattreatments
On Tuesday, Darren Salter, the senior coroner in the southern English county of Oxfordshire, says the official cause of Michael's death was “dilated cardiomyopathy with myocarditis and fatty liver.”
Total deaths from heart disease, stroke, diabetes and hypertension - known collectively as cardiometabolic disease, the leading cause of preventable death worldwide - have been increasing since 2011.
Fainting is defined as temporary getting unconscious and then returning to full wakefulness. During fainting, there is a loss of muscle power and one tend to fall or slump.
Table 5 shows five-year cause-specific survival and adjusted relative risk of cancer death by race/ethnicity in persons diagnosed in 2006 to 2012 for all cancer sites combined and for the 20 most common cancers. The five-year survival for all sites combined was highest for Hispanics (68.2%, 95% CI = 67.9% to 68.4%) and NHW (68.0%, 95% CI = 67.9% to 68.1%), followed by NHAPI (66.7%, 95% CI = 66.4% to 67.0%), NHB (62.8%, 95% CI = 62.6% to 63.0%), and NHAI/AN (60.5%, 95% CI = 59.5% to 61.5%). The adjusted relative risk of death after a diagnosis of cancer (HR) was statistically significantly higher in NHB than NHW for all cancers combined (HR = 1.33, 95% CI = 1.32 to 1.34) and for most cancer sites, with the excess risk most notable for female breast, oral cavity, and uterine cancers and non-Hodgkin lymphoma. Compared with NHW, Hispanics had statistically significantly higher risk of death for 10 of the 20 cancers, most notably for leukemia, but they have lower risk of death after diagnosis for ...
Note: ---- means data not available.. Rows do not sum to the listed totals because not all causes of registered deaths are listed on this table. To calculate the percent of registered deaths in a country that were due to a particular cause, divide the number of registered deaths in a country due to a certain cause by the total number of registered deaths in the country and multiply the result by 100. Example: Calculate the percent of registered deaths in Belarus due to senility. This calculation would be 10,872/134,867=.081 and .081x100=8.1% Source: World Health Organization, WHO Mortality Database, 2003. ...
NHS staff must begin treating patients suspected of having potentially lethal sepsis within one hour, the watchdog has said in a bid to crack down on avoidable deaths.
Millions of dogs and cats are at risk of avoidable death from an increase in unproven anti-vaccination “remedies” being sold online, the RSPCA has warned.
Read Deaths Latest News, Photos, Videos, Live updates and Top Headlines on Deaths at ABPLive.in and also stay tuned to explore more on Deaths
The figures for causes of death between 2001 and 2009 show a general decline in other major causes, such as heart disease, but the report acknowledged that cancer and vascular and respiratory conditions were still the big killers. However, more than one in 10 deaths among people in their forties followed a liver condition, and its place in the medical league table of "years of life lost" is high: 37% of liver disease deaths for people in their forties were alcohol related, split 41% for men and 30% for women ...
The leading causes of U.S. deaths in 2007 were heart disease, cancer, stroke, lower respiratory diseases, accidents, Alzheimers, diabetes and influenza.
On Death and Dying audiobook on demand - Dr. Elisabeth Kübler-Ross created her classic seminal work, On Death and Dying, to offer us a new perspective on the terminally ill. It is not a psychoanalytic study, nor is it a how-to manual for managing death. Rather, it refocuses on the patient...
Chronic triggers that preceded the expressed desire for hastened death included debilitating progression of disease; perception of chronic and progressive loss of social support, dignity, autonomy, and sense of worth; and perception of being a burden to self or others in the present or future. Acute events preceding expression of a desire for hastened death included uncontrolled pain, shortness of breath, and medical information that produced fear, hopelessness, and a sense of dread.. 9 distinct, but sometimes intertwined and overlapping, meanings and uses of an expressed desire for hastened death were extrapolated from the narratives. (1) A manifestation of the will to live. This theme was named the "primary paradox" because patients behaviour evidenced the will to live despite having expressed a desire for hastened death on ⩾1 occasion. For example, "See, theres a problem while planning or pursuing your death… On the one hand, I am saying all these things, and, on the other hand, I am ...
Chronic triggers that preceded the expressed desire for hastened death included debilitating progression of disease; perception of chronic and progressive loss of social support, dignity, autonomy, and sense of worth; and perception of being a burden to self or others in the present or future. Acute events preceding expression of a desire for hastened death included uncontrolled pain, shortness of breath, and medical information that produced fear, hopelessness, and a sense of dread.. 9 distinct, but sometimes intertwined and overlapping, meanings and uses of an expressed desire for hastened death were extrapolated from the narratives. (1) A manifestation of the will to live. This theme was named the "primary paradox" because patients behaviour evidenced the will to live despite having expressed a desire for hastened death on ⩾1 occasion. For example, "See, theres a problem while planning or pursuing your death… On the one hand, I am saying all these things, and, on the other hand, I am ...
How can we, as academics, understand cultural responses to mortality?. Is every response to death - over time and over place - uniquely personal or essentially the same?. This conference focusses on the impact of mortality on culture, and the ways in which the very fact of death has shaped human behaviour, evidenced through thought, action, production and expression. The conference seeks to re-engage with the study of mortality as an academic enterprise, supported by evidence and framed by theoretical engagement. No discipline is excluded and we are encouraging researchers including postgraduates to contribute who might not consider themselves death scholars, with work that overlaps with death and the dead.. We welcome contributions on topics such as but not limited to:. ...
I recently finished reading "The Lean Startup" by Eric Ries. If you havent read it already, I highly recommend it - the book is full of great insights on how to make new products, whether youre a startup or a big, established company. Im not on board with all of his recommendations (e.g. split testing every little change) but he gets so much right (small batches, experiment-driven product development, stay stubborn on vision but flexible on execution, etc.) that I cant help but look past the occasional lapse in the details.. In this post, Im going to discuss a simple technique that Eric mentions near the end of the book: the technique of the Five Whys. The goal of the technique is to help us look past the immediate cause of a problem to find more systemic causes. These systemic causes often indicate bigger problems with the culture and structure of the organization.. The Five Whys technique is very simple in concept. When a problem occurs, we ask "Why" not just once, to identify the ...
May it please your Royal Highness,---God, has in his providence, again visited this unhappy parish with cholera in its most frightful form. And as the parish is one of the estates of the Duchy Cornwall, and your Royal Highness is president of the council of the Duchy, I am constrained by feelings and convictions which I cannot resist; to bring the case and the matters connected with it immediately and fully before your notice. I must write in the few intervals of rest from almost incessant attention to the sick. Of the immediate cause of its introduction among us I have my opinion, and I shall not hesitate to express it. But the main subject on which I venture thus to address your Royal Highness is that of the circumstances through which this and other epidemics, when once introduced into a portion of this parish, are fostered and aggregated. And my excuse for this liberty I thus take is conviction long since felt, but strengthened as during the last 12 days I have passed from house to house of ...
Deoxyribonucleic acid synthesis was straight related to cell country and programmed cell death was switched off in the event of cell distributing. Cellular proliferation and programmed cell death was determined under changing growing status. When cells were grown on different sized, square-shaped FN coated islands, programmed cell death declined and DNA synthesis increased with size runing from 75 to 3000µm2. Death rate for different sized islands were measured by TUNEL staining and the consequences were plotted and showed that a larger surface country of the island possessed a better status for cell spreading and growing This was besides observed that by increasing cell distributing on a homogeneous FN coated would take to cell growing when the entire country of cell to ECM fond regard were kept changeless. Under this conditions growing conditions, DNA synthesis increased and programmed cell death decreased with increased in cell spreading. Using substrates coated with specific antibodies to ...
Death rates from CVD and CHD have declined dramatically in Australia since their peak in the mid 1960s. This report quantifies the number of lives saved since the peak and looks briefly at the age and sex population groups where the impact was likely to have been highest.. ...
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I am trying to help a friend interpret an autopsy report based on the death of his cousin. Could someone let us know what the following terms and statements mean? No one has explained the autopsy report to him and the medical stataements found in the report are confusing to someone without a medical background ...
The squeeze on public finances since 2010 is linked to nearly 120,000 excess deaths in England, with the over-60s and care home residents bearing the brunt, reveals the first study of its kind, published in the online journal BMJ Open.
Hypertension In Children Lecture contains Definitions, Causes, When to take BP in a child, Stages of HTN, Investigations, Treatment options
Wouldnt it make more sense to be more afraid of whats more likely to kill you? Yes, but thats not how we perceive risks. Risks have psychological and emotional characteristics that make some feel scarier than others, the probabilities notwithstanding. A long, painful cancer death may not be any worse than a long, painful heart disease death, but we think it would be, and feel we cant control it, and that makes cancer more feared. That is precisely what a new proposal at the Environmental Protection Agency is trying to acknowledge. When assessing whether a new regulation would be worth the money, the agency projects how many lives it would save vs. the costs of implementing it. But now, the EPA suggests that death by cancer is so frightening to the public, cancer deaths should carry greater weight in its calculations than deaths by other causes. This is an approach that may have some ethical and emotional appeal, but it carries serious dangers for us all. . . . Under its "cancer premium," the ...
This article is about the medical causes of coughing after eating. The main cause of cough after eating meal is mainly allergy, the other problems which
(Diseases Database): The follow list shows some of the possible medical causes of Abdominal Pain that are listed by the Diseases Database: Zinc Recurrent
Rolf Erb, former head of the Erb Group, which went bust in 2003 with debts of CHF2 billion ($1.98 billion), died of natural causes.
Helpful, trusted answers from doctors: Dr. Poochikian on my breathing feels restricted: Need more info: short of breath, feeling not getting enough air in, chest tightness, anxiety, wheezy, coughing, stomach gas, constipated, etc? All these are signs of different causes of breathing abnormalities.
... Read about ten different causes here an upper GI bleed, to polyps, hemorrhoids, IBD, cancer, and more.
Necrosis of tissue is probably becuase of lack of adequate blood supply to the tissue. Numbness can have different causes, but if circulation is compromised it could very well be that that is affecting the nerves in the area and making it numb ...
Bouts of nausea can have many different causes. Regardless of the cause, here are four surprising treatments that can help you feel a little bit better.
Physician-coded verbal autopsy (PCVA) is the most widely used method to determine causes of death (CODs) in countries where medical certification of death is uncommon. Computer-coded verbal autopsy (CCVA) methods have been proposed as a faster and cheaper alternative to PCVA, though they have not been widely compared to PCVA or to each other. We compared the performance of open-source random forest, open-source tariff method, InterVA-4, and the King-Lu method to PCVA on five datasets comprising over 24,000 verbal autopsies from low- and middle-income countries. Metrics to assess performance were positive predictive value and partial chance-corrected concordance at the individual level, and cause-specific mortality fraction accuracy and cause-specific mortality fraction error at the population level. The positive predictive value for the most probable COD predicted by the four CCVA methods averaged about 43% to 44% across the datasets. The average positive predictive value improved for the top three most
Unintentional injuries are the leading cause of deaths among persons aged 0-19 years in the United States. Quantifying years of potential life lost (YPLL) highlights childhood causes of mortality and provides a simple method to identify important causes of premature death and specific groups in need of intervention (1). Deaths attributed to unintentional injuries among persons aged 0-19 years number approximately 12,000 each year in the United States; another 9 million young persons are treated for nonfatal injuries in emergency departments (2). To estimate the burden of premature deaths attributed to unintentional injuries among persons aged 0-19 years, CDC calculated state-specific YPLL by sex, age, race, and injury mechanism based on data from the National Vital Statistics System multiple cause of death files for the period 2000-2009. This report summarizes the results of that analysis, which found that an average of 890 years of potential life were lost each year because of unintentional ...
Crude death rate,Deaths: by certain causes,Deaths by certain causes as a % of total deaths,Deaths in first year of life as a % of total deaths,Deaths: total and in first year of life,Difference between female and male life expectancy,Life expectancy at 65 of female population: total and by healthy and unhealthy life years,Life expectancy at 65 of male population: total and by healthy and unhealthy life years,Healthy life years at 65: by sex,Infant mortality rate,Infant deaths: Late foetal and neonatal,Life expectancy at 65: by sex,Life expectancy at birth: total and by sex,Maternal mortality,Maternal mortality rate,Neonatal mortality rates and late foetal mortality rate
Life expectancy at birth; total (years) in Gambia was last measured at 58.83 in 2013, according to the World Bank. Life expectancy at birth indicates the number of years a newborn infant would live if prevailing patterns of mortality at the time of its birth were to stay the same throughout its life.This page has the latest values, historical data, forecasts, charts, statistics, an economic calendar and news for Life expectancy at birth - total (years) in Gambia.
Decreasing trends in measles mortality have been reported in recent years. However, such estimates of measles mortality have depended heavily on assumed regional measles case fatality risks (CFRs) and made little use of mortality data from low- and middle-income countries in general and India, the country with the highest measles burden globally, in particular. We constructed a dynamic model of measles transmission in India with parameters that were empirically inferred using spectral analysis from a time series of measles mortality extracted from the Million Death Study, an ongoing longitudinal study recording deaths across 2.4 million Indian households and attributing causes of death using verbal autopsy. The model was then used to estimate the measles CFR, the number of measles deaths, and the impact of vaccination in 2000-2015 among under-five children in India and in the states of Bihar and Uttar Pradesh (UP), two states with large populations and the highest numbers of measles deaths in India. We
A death certificate is a legal documentation of the date, fact and cause of death. The medical portion of the death certificate is to be signed by the physician (MD, DO), advance practice registered nurse (APRN), physician assistant (PA), or pathologist according to Connecticut Public Act No. 04-255. Maureen Weavers 2005 article summarizes this public act.. The Autopsy Service makes every effort to ensure the medical portion of the death certificate is properly filled out to expedite the release of a patient into the care of a funeral home or cremation service. Since only the medical portion is filled out, the Autopsy Service cannot release the death certificate to the family directly.. The funeral home or cremation service will complete the demographic portion of the death certificate and file the completed document with Vital Statistics. The funeral director provides the family with one certified copy of the death certificate. Please contact your funeral home or cremation service for more ...
This data collection includes information about the cause of all recorded deaths occurring in the United States, Puerto Rico, the Virgin Islands, Guam, American Samoa, and the Commonwealth of the Northern Marianas during 1998. Data are provided concerning underlying causes of death, multiple conditions that caused the death, place of death, residence of the deceased (e.g., region, division, state, county), whether an autopsy was performed, and the month and day of the week of the death. In addition, data are supplied on the sex, race, age, marital status, education, usual occupation, and origin or descent of the deceased. In addition to the combined Territory Public-Use file (Part 2), a subset based on state of occurrence has been created for Puerto Rico, Virgin Islands, American Samoa, Guam, and Northern Marianas. Mortality detail data for 1998 also can be extracted from this file. The mortality detail records are contained in the first 159 positions of these multiple cause records. The ...
In this paper, we investigated inequalities in the distribution of neonatal and postneonatal mortality in rural areas of Iran over the course of 16 years. Our findings showed that despite notable decreases in neonatal and postneonatal mortality rates over the study period, inequalities in distribution of these measures in Iran persisted, and higher neonatal and postneonatal mortality rates were still reported in areas of lower socioeconomic status.. The regression models built to evaluate neonatal mortality rates showed that the proportions of births occurring in hospitals and literate women of reproductive age were associated with lower mortality rates; additionally, higher neonatal mortality rates were observed in areas with a higher proportion of infants classified as having low birth weight. Moreover, in the evaluation of postneonatal mortality rates, the proportion of births occurring in hospitals and to younger mothers were associated with lower mortality rates.. We also evaluated ...
Death. (BrUp 1.2.7. trans. Müller) God of death implicitly, in eṣa vā aśvamedho ya eṣa tapati "verily, that Ashvamedha is that ... Mara (Hindu goddess), the goddess of death according to Hindu mythology. Mṛtyu-māra as death in Buddhism or Māra, a "demon" of ... Mṛtyu (from Vedic Sanskrit: मृत्यु IAST:mRtyu ; Latin cognate mortis), is a Sanskrit word meaning Death. Mṛtyu or Death is ... Yama (Sanskrit: यम) is the lord of death in Hinduism and Buddhism. Yama in Hinduism. Yama in Buddhism. The Brhadaranyaka ...
p. 2. "Death". Waikato Times. XLI (3315). 26 September 1893. p. 4. Retrieved 23 February 2014. "Local and General". The Star ( ... "Death". The Timaru Herald. LV (5743). 8 August 1893. p. 2. Retrieved 23 February 2014. "Marriages". The Star (5733). 28 ... "Deaths". The Press. LXVII (14051). 24 May 1911. p. 1. Retrieved 22 February 2014. Harper, Margaret. "Christchurch Street Names ...
"Death". Mataura Ensign. 6 December 1892. p. 4. Retrieved 31 January 2017. ...
"Death". Competition Science Vision. August 1998. p. 792. Miles, Dick (6 May 1968). "The Channel Is a Place to Suffer". Sports ...
Death.' to the C.H.A.O.S. Split album released on July 20, 2017 through Art of Propaganda. The album was dedicated to the ... There's no conformity involved as far as genres-black metal, death metal, whatever. I just write riffs that feel right to me. ... Though the band's style can be broadly categorized as blending elements of death metal or black metal, critics have noted the ... muddy blast-beat death/black metal succeeds and it's succeeded by abysmal doom metal passages." NPR Music compared the EP to ...
Mea'ole died a year later in 1963, leaving Tanumafili as the sole holder of the office until his death in 2007, aged 94. His ... death. The position is that of a ceremonial head of state, while actual power is held by the Prime Minister, whom the O le Ao o ...
Death? Get over it". SFX. Retrieved 2011-07-14. The New World on Tardis Data Core, an external wiki The New World - Script at ...
zimbabweournalists.com details of death Jan Raath, "Double cross turns tables on Mugabe militia", The Times, 24 October 2003, p ... Death." [1] On taking up his office, Dr Jokonya offered regular meetings with journalists to discuss their coverage. He told ... "Jokonya death: Family rules out foul play", Zimbabwe Herald, 26 June 2006. ...
How harsh his midnight cry! It seems to shriek, in mournful sounds, Death! Death! The Prince of the Air certainly causes them [ ... The funnel-shaped cloud deals death and destruction to all that come within its whirling, deadly grasp. When seeing the ...
Death. Unlucky years are different for men and women, in the old way of thinking, for men 25, 42, 61 are unlucky and 19, 33, 37 ...
dEatH. rOck N' roLL. , Garage Grrls , Jami Deadly". Horror Garage. Retrieved October 24, 2013. https://www.youtube.com/user/ ...
"Death". Taranaki Herald. 3 October 1882. p. 2. Retrieved 29 August 2015. "Cemetery search". New Plymouth District Council. ...
"Death of Mr John White". West Coast Times (2322). 6 September 1876. p. 2. Retrieved 8 March 2014. Scholefield 1950, p. 243. ... "Death". Grey River Argus. XXXVIII (6773). 2 June 1890. p. 2. Retrieved 8 March 2014. "Wellington News". The Star (6869). 3 June ... "Death of another Legislative Councillor". Ashburton Guardian. XII (2430). 2 June 1890. p. 2. Retrieved 8 March 2014. ... He was a member of the Legislative Council from 9 July 1872 until his death. Lahmann died on to 1 June 1890 at his residence in ...
"Death". The Nelson Evening Mail. XXIII (325). 24 December 1889. p. 2. Retrieved 21 June 2015. Sources Richardson, Lesley (1995 ...
"Death". DartMUD Helpfiles. Retrieved 2008-03-29. "Hexes". Dartmud Helpfiles. Retrieved 2008-03-29. "Text versus Graphics". Raph ... Permanent Death: DartMUD is targeted at hard-core mudders, people willing to risk permadeath - a common occurrence - in order ...
"Death". Colonist. XXXV (7404). 18 August 1892. p. 3. Retrieved 2 February 2016. "Secondary schools". Cyclopedia of New Zealand ... "Births, Marriages, and Deaths". Wellington Independent. XXI (2480). 14 February 1867. p. 4. Retrieved 2 February 2016. "Married ...
DEATH. LIARDET.- On the 21st March, at Vogeltown, W. F. Evelyn Liardet, aged 79 years, father of Mr. Hector and Sinclair ... "DEATH OF MR. JOHN EVELYN LIARDET". The Sydney Morning Herald. National Library of Australia. 30 October 1902. p. 7. Retrieved ...
"Death". The Press. III (294). 9 October 1863. p. 2. Retrieved 8 June 2016. Greenaway, Richard L. N. (June 2007). "Barbadoes ...
Death (Survivorship, Actions for Death, Death Certificate, Uniform Anatomical Gift Act, Living Wills); Decedents' Estates; ... Presumption of death or survivorship, see Death; Pretermitted children, see Wills; PRINCIPAL AND AGENT - See also Brokers, ... Wrongful death, see Death. Magrauth, Joseph Walker, ed. (1931). Sixty-Third Year, The Martindale-Hubbbell Law Directory (Annual ... Interstate Arbitration of Death Taxes; Interstate Compromise of Death Taxes; Interstate Family Support; Interstate Family ...
"Births, Marriages, and Deaths". Otago Daily Times (3300). 3 September 1872. p. 3. Retrieved 23 May 2012. "Deaths". Otago ... "Deaths". Otago Daily Times (11455). 21 June 1899. p. 4. Retrieved 22 May 2012. "Cemeteries search". Dunedin City Council. ... "Death". Otago Daily Times (3659). 27 October 1873. p. 2. Retrieved 22 May 2012. "Cemeteries search". Dunedin City Council. ... "Deaths". Otago Daily Times (2257). 30 April 1869. p. 2. Retrieved 22 May 2012. "Cemeteries search". Dunedin City Council. ...
At the time of his death he had been suffering from influenza and fever. Before his death he had been notified that the ... and his resulting distress may have contributed to his death. Because of the timing of his death, some people speculated that ... After Lim's death, many of his children left Burma, and his descendants now live in various Commonwealth countries, including ... After Lim's death, many stories circulated orally among the residents of Yangon concerning the sudden circumstances of his ...
"Death". Auckland Star. III (742). 31 May 1872. p. 2. Retrieved 30 December 2014. Jackson, William Keith (1972). The New Zealand ... His career culminated as a member of the New Zealand Legislative Council from 1866 until his death in 1872. Captain Peacocke's ... The headstone over their grave reads: "In death they were not divided". Swami, V. Narayan (27 January 2009). "Ooty Preserved : ... but his membership lapsed due to non-attendance and his final date of membership is the same as his death date. Isabella ...
"Death". The Timaru Herald. XXXII (1706). 10 March 1880. p. 2. Retrieved 25 August 2014. ...
Christ's passion and death Maranam jayicha veera ... (Hero, that won over death ...) - Resurrection. Yesu varum vegathil - ... The letter he sent to the assembly fellowship in Paravur four years prior to his death reflects the hunger in his heart for ... Samayamam rathathil njaan swerga yathra cheyyunnu ... (In the chariot of time I am on my homeward journey ...) - Death. His ...
Coroners and others who fill out death certificates have not always listed a specific drug as a cause of death. They are being ... The top 10 drugs listed on death certificates havent changed since 2010, the team found, but their order in terms of deaths ... It was the first federal government report to look not only at drug overdose deaths in general, but to dig down and see which ... The report found that while oxycodone was the top killer in 2010 and 2011, heroin passed it as a cause of death stating in 2012 ...
... which is the leading cause of death in children between 1 month and one year old ... Learn how to reduce the risk of Sudden Infant Death Syndrome (SIDS), ... Sudden infant death syndrome (SIDS) is the sudden, unexplained death of an infant younger than one year old. Some people call ... Sudden Unexpected Infant Death and Sudden Infant Death Syndrome: Reducing the Risk (Centers for Disease Control and Prevention) ...
Charts of the 10 leading causes of death and injury by age group for the US ...
This map shows death rates from heart disease in women in the United States. The darker red indicates a higher death rate. ... Heron M. Deaths: Leading causes for 2016pdf icon [PDF-2.3M]. National Vital Statistics Reports. 2018;67(6). ... Underlying Cause of Death 1999-2017 on CDC WONDER Online Database, released December 2018. Data are from the Multiple Cause of ... Heart disease is the leading cause of death for women in the United States, killing 299,578 women in 2017-or about 1 in every 5 ...
Times of death and convulsions in the 24 hours prior to each death were identified during off-line visual inspection of records ... Sudden unexpected death in epilepsy (SUDEP) is the most common cause of death in intractable epilepsies, but physiological ... Sudden unexpected death in a mouse model of Dravet syndrome.. Kalume F1, Westenbroek RE, Cheah CS, Yu FH, Oakley JC, Scheuer T ... illustrating the seizure and bradycardia preceding death. Time of death was defined as the moment when the power of the EEG ...
17 The death certificate database includes all deaths in Ontario. Causes of death were determined from death certificates, ... Mean age at death was 39 years. Among women 18-44 years of age, the most common causes of death were HIV/AIDS and drug overdose ... 31, 1997, or, in the case of decedents, date of death.14,17 Mortality rates were calculated by dividing the number of deaths by ... Deaths in the study population were ascertained by comparing the database of shelter users with Ontario death certificate ...
A fact sheet that describes the incidence and death rates for selected cancers among racial and ethnic groups living in the ... The lowest death rates for prostate cancer are found in Asian/Pacific Islander men. Incidence and death rates for prostate ... The highest death rate from cervical cancer is among African American/Black women. Incidence and death rates for cervical ... For all cancers combined, the death rate is 25 percent higher for African Americans/Blacks than for Whites. Incidence and death ...
SIDS is the leading cause of death among infants 1 month to 1 year old. Though SIDS remains unpredictable, you can help reduce ... Sudden infant death syndrome (SIDS) is the sudden and unexplained death of a baby younger than 1 year old. Most SIDS deaths are ... Most SIDS deaths happen in babies 2 to 4 months old, and cases rise during cold weather. Black and Native American infants are ... When considering which babies could be most at risk, no single thing is likely to cause a SIDS death. Rather, several risk ...
3: Alzheimers doesnt lead to death.. Sadly, its the sixth leading cause of death in the U.S. Most people live 8 to 10 years ...
... a death rate of 1 in 24,000 translates to 1.5 deaths per day (541 children annually); while a death rate of 1 in 500,000 ... Death rate is likely to be significantly higher from non-medicalized circumcisions performed at home, en masse, and/or under ... Estimated Number of Circumcision-Related Deaths. (based on 1994 world estimate of circumcised males: 647,701,200). 1,295 to ... male circumcisions performed, or the number of circumcision-related complications or deaths. ...
Death. I think rather of the unknown Afterwards, the next Event, the Land of Finding Out--the Great Adventure that s before us ... For the next twenty years his friends met on the anniversary of his death to visit his grave and talk about him fondly. For the ...
... When an U.S. citizen dies abroad, the Bureau of Consular Affairs assists the family and friends. The Bureau of ... For more information on the Consular Report of the Death of an American Abroad, and other services that a consular officer can ... Upon issuance of a local (foreign) death certificate, the nearest embassy or consulate may prepare a Consular Report of the ... citizen who dies abroad if the deceased has no legal representative or next-of-kin in the country where the death occurred, ...
Sudden death (athletes). Sports[edit]. *Sudden death (sport), a form of competition where play ends as soon as one competitor ... Sudden Infant Death Syndrome. This disambiguation page lists articles associated with the title Sudden death.. If an internal ... 1958 NFL Championship Game, nicknamed "Sudden Death" for its dramatic ending. Entertainment[edit]. *Sudden Death (1995 film), a ... Sudden cardiac death, natural death from cardiac causes. * ... Sudden Death or Sudden death may refer to:. * ...
Fraudulent death[edit]. In some cases, a legal declaration of death is fraudulent. Several people have faked their own deaths ... When a death has been registered in a civil registry, a death certificate may be issued. Such death certificate may be required ... Two categories of legal death are death determined by irreversible cessation of heartbeat and breathing (cardiopulmonary death ... Immunogenic cell death. Ischemic cell death. Pyknosis. Karyorrhexis. Karyolysis. Mitotic catastrophe. Suicide gene. *Abortion ...
It covers programmed cell death, cell death induced by toxic agents, differentiation and their relation to cell proliferation. ... Cell death and Differentiation provides an accessible source of up-to-date information for scientists and clinicians. ... Welcome to Cell Death & Differentiation Devoted to the cell biology, molecular biology and biochemistry of cell death and ... the latest web focus which highlights some of the latest research from China covered by the three journals in the Cell Death ...
... Collected by Mang Ali. WAMY Series on Islam World Assembly of Muslim Youth (WAMY). P.O.Box 10845. Riyadh 11443 ... "Until, when death comes to one of them, he says: O my Lord! Send me back (to life),- In order that I may work righteousness in ... Fifthly, Gods attributes of Justice and Mercy have no meaning if there is no life after death. Further Readings on Islam: *T. ... Such persons realize their folly only at the time of their death and wish to be given a further chance in the world but in vain ...
Eternal Death is the second album of Crown of Thorns. It was originally released in 1997 and later re-issued under the bands ... "Death of God" - 10:08 (M. Olsfelt) Marcus Sunesson - Guitar Janne Saarenpää - Drums Magnus Olsfelt - Bass Guitar Johan ...
Death in Sanatorium B.J. Winslow - Death in Morgue Joan Farrell - Traci The New York Times DVD Talk Death Tunnel on IMDb Death ... Death Tunnel is a 2005 horror movie filmed at the Waverly Hills Sanatorium. It stars Steffany Huckaby, Annie Burgstede, Kristin ...
Death anxiety may refer to: Existential angst The Sickness Unto Death & The Concept of Anxiety, psychological works on angst by ... Death Anxiety (song) by the group Bleeding Through. ... Søren Kierkegaard Death anxiety (psychology) Terror management ...
Ecological death is the inability of an organism to function in an ecological context, leading to death. This term can be used ... it can also lead to ecological death. An effect caused by DDT is shell thinning in bird eggs, leading to the death of the chick ... If this alteration does not directly cause death, but impacts the behavior or physiology of the organism, it can also lead to ... This is an example of a physiological sublethal effect leading to ecological death. Scott, G.R., and K.A. Sloman. 2004. The ...
Texas jurys quick death sentence for John William King, which the WP puts on page 3, while the LAT runs it on page 28. The... ... USAT leads with a Jasper, Texas jurys quick death sentence for John William King, which the WP puts on page 3, while the LAT ... Also, the papers dont mention it, but this story should give pause to anyone who thinks the death penalty is a deterrent. The ... The paper goes on to report that since the Supreme Court reinstated the death penalty in 1976, nationwide eight whites have ...
the death) The collapse or end of something. England scored a goal at the death to even the score at one all. death of the ... death from natural causes), mate whawhati tata (sudden death), mate koeo (natural death), hautapu (by violence) ... death (countable and uncountable, plural deaths). *The cessation of life and all associated processes; the end of an organisms ... often capitalized) The personification of death as a hooded figure with a scythe; the Grim Reaper. When death walked in, a ...
I do not believe it is possible to know how much of his misery at this time was due to malaria, to medicines, or to the death ... David Brown: People with MEN 2B are definitely prone to illness and early death, which is why Lincolns longevity (he died at ... Arlington, Va.: Are individuals with this condition more prone to illness and early death? I notice in pictures of Lincolns ... The first was in connection with the death of Lincolns near-fiancee, Ann Rutledge. (This is a hugely controversial point with ...
What happens after death?. So when it comes to death, what are we sure of? Well we know what happens to your body from the ... Take the tragic deaths of people caught in the 9/11 bombings or the death of Princess Diana. This may not be grief after all, ... Life after death?. Perhaps the most intriguing question for many people is whether or not there is life after death. A few have ... A week after death, blood-coloured blisters appear on the skin and the slightest pressure causes the top layer to slip off. ...
When death is on thy brow? The world! what means it? Mine is here!. I will not leave thee now. "I have been with thee in thine ... FAITHFUL TILL DEATH. 1308. One of the ladies most admired by the ancient Romans was Arria, the wife of Cæcina Pætus, a Roman ... "Faithful Till Death." by Charlotte M. Yonge (1823-1901) From: A Book of Golden Deeds.. (1864) by Charlotte M. Yonge. London: ... Seeing him waver, his wife, who was resolved to be with him in death as in life, took the dagger from his hand, plunged it into ...
  • Born in Wadowice, Poland, on May 18, 1920, Karol Wojtyla was raised primarily by his father, a military officer also named Karol, after his mother's death in 1929. (ewtn.com)
  • A Dallas police detective then went to notify Keira Reid of her mother's death. (usatoday.com)
  • As NPR's Scott Simon live-tweeted his mother's death from her hospital bed in Chicago last night, I was reminded just how much technology has altered how we grieve. (forbes.com)
  • A record cannot be identified as available prior to purchase because under State statute (IC 16-37-1-11 and IC 37-1-11.5), the fee associated with a death certificate is for the ISDH Vital Records office to search the records to determine if a record is on file. (in.gov)
  • O'Shaughnessy, Perri, Presumption of Death, (Pamela n Mary -2 sisters team-writing) Fires set by an arsonist in Carmel Valley Village - against development of the slopes. (google.com)
  • A cohort of 1981 women not accompanied by dependent children who used homeless shelters in Toronto in 1995 was observed for death over a mean of 2.6 years. (cmaj.ca)
  • Nel 1995 anche il Live After Death , come tutti gli altri album pubblicati dagli Iron Maiden fino a quel momento, venne ripubblicato in versione doppio CD con le b-side dei singoli inseriti nel secondo CD (per la precisione i brani Losfer Words (Big 'Orra) , Sanctuary e Murders in the Rue Morgue ). (wikipedia.org)
  • Furman v. Georgia (1972): The Supreme Court declared the death penalty unconstitutional, as cruel and unusual punishment in violation of the Eight Amendment, and finding that the administration of the ultimate punishment was arbitrary and capricious. (aclu.org)
  • The reformers in recent years also persuaded the authorities to require Supreme Court approval for all death sentences and to make torture inadmissible in capital cases. (cnbc.com)
  • Since the US Supreme Court reintroduced the ultimate sanction in 1976, 1,099 people have gone to their deaths - 53 of them in 2006. (theregister.co.uk)
  • It has been a poor relation to another, more exciting type of cell death called "apoptosis", or programmed cell death. (newscientist.com)
  • When cell death first captured biologists' attention in the late 1980s, it was perhaps inevitable that apoptosis would take centre stage. (newscientist.com)
  • Apoptosis by death factor. (nih.gov)
  • However, apoptosis does not necessarily require protein synthesis and is usually not programmed (meaning that the sequence of death is coded in the genes) except in the generic sense that it was preprogrammed into the cell and simply required release or activation. (encyclopedia.com)
  • Simon's Twitter feed informed the world of his mother's passing late last night , and this morning expounded upon the difficulty of explaining death. (forbes.com)
  • Social media feeds have long been responsible for informing users of celebrity deaths, yet sites like Twitter and Facebook are increasingly becoming venues to express grief. (forbes.com)
  • When Steve Jobs passed away in October 2011, Twitter overflowed with outpourings of grief for the Apple co-founder, as tweets mentioning "Steve Jobs" accounting for 15% of all content on the platform in the hours following his death. (forbes.com)
  • Since 1973, 138 death-row prisoners have been released because they were innocent. (aclu.org)
  • Japan has often been criticised internationally for its use of the death penalty and the fact that death row prisoners and their families are not told about the execution date in advance. (smh.com.au)
  • The country last executed prisoners exactly a year earlier, when the conservative Liberal Democratic Party still ruled the country, putting to death three inmates including one Chinese national, also for multiple murder. (smh.com.au)
  • To write a letter on behalf of Juan Raul Garza, as well as the other prisoners currently on state and federal death row, visit our Death Row Roll Call . (thenation.com)
  • In the July-August 2003 Atlantic Monthly , Alan Berlow wrote a long, carefully documented article, "The Texas Clemency Memos," which told of the role of Gonzales, then legal counsel to Texas governor George W. Bush, in deciding the fate of prisoners on death row, including the mentally retarded. (villagevoice.com)
  • I understand that I'm probably in the minority in this country in my opposition to the death penalty. (scienceblogs.com)
  • I sometimes spoke of the book in the classes Holly took with me and of my opposition to the death penalty, and Holly countered that she endured a similar experience, the murder of a classmate, but believed the death penalty was justifiable. (huffingtonpost.com)
  • A ) Incidence and duration of spontaneous generalized tonic-clonic convulsions 24 hours prior to death. (nih.gov)
  • A close look at cancer incidence and death statistics reveals that certain groups in this country suffer disproportionately from cancer and its associated effects, including premature death. (cancer.gov)
  • For example, African Americans/Blacks, Asian Americans, Hispanic/Latinos, American Indians, Alaska Natives, and underserved Whites are more likely than the general population to have higher incidence and death statistics for certain types of cancer. (cancer.gov)
  • Complex and interrelated factors contribute to the observed disparities in cancer incidence and death among racial, ethnic, and underserved groups. (cancer.gov)
  • How does NCI gather data on cancer incidence and death for various population groups in the United States? (cancer.gov)
  • The incidence and death statistics presented in this fact sheet are from Tables I-23 through I-28 of the SEER Cancer Statistics Review, 1975-2004 ( http://seer.cancer.gov/csr/1975_2004 ). (cancer.gov)
  • When the statistics focus on cancer incidence and death in a single gender for example, on female breast cancer or male prostate cancer the numbers are per 100,000 persons of that gender. (cancer.gov)
  • Age-adjustment allows cancer incidence and death statistics (expressed below as cancer incidence and death "rates ) for these population groups to be compared. (cancer.gov)
  • What are the overall cancer incidence and death rates for different populations living in the United States? (cancer.gov)
  • By the early twentieth century, the incidence of death in Western cultures began to shift dramatically, in ways that affected children particularly. (encyclopedia.com)
  • In 2009, the number of new death sentences was 112 , the lowest level in 30 years. (aclu.org)
  • Federal prosecutors are twice as likely to reach plea agreements avoiding death sentences with white than with black and Hispanic capital defendants. (thenation.com)
  • The bigger death gratuity is retroactive to Oct. 7, 2001, the start of Operation Enduring Freedom in Afghanistan. (military.com)
  • Death records in the ISDH Vital Records office begin with 1900. (in.gov)
  • Prior to 1900, records of death are filed only with the local health department in the county where the death actually occurred. (in.gov)
  • For deaths occurring from 1900 to 1917, the city and/or county of death is required in order to locate the record. (in.gov)
  • We studied the mechanism of premature death in Scn1a heterozygous KO mice and conditional brain- and cardiac-specific KOs. (nih.gov)
  • Ecological death may be caused by sublethal toxicological effects that can be behavioral, physiological, biochemical, or histological. (wikipedia.org)
  • This is an example of physiological and biochemical sublethal effects leading to ecological death of the chick. (wikipedia.org)
  • If this restraint is removed when a cell is challenged, it will default to the self-destruct mode and, assuming that the challenge is not so severe that the cell becomes necrotic, it will undergo this physiological form of death. (encyclopedia.com)
  • Grief therapist Lisa Leonard told Mashable that 'being able to access the lost one's profile after death is beneficial. (forbes.com)
  • Explore leading causes of death charts in image format . (cdc.gov)
  • We report mortality rates and causes of death in a cohort of women who used homeless shelters in Toronto. (cmaj.ca)
  • But most SIDS diagnoses come only after all other possible causes of death have been ruled out. (kidshealth.org)
  • In the EU, standardised death rates were higher for men than for women for nearly all of the main causes of death in 2015. (europa.eu)
  • This article gives an overview of recent statistics on causes of death in the European Union (EU) . (europa.eu)
  • The latest estimated information for the EU-28 relating to causes of death is available for the 2015 reference period . (europa.eu)
  • Table 1 shows that diseases of the circulatory system and cancer (malignant neoplasms) were, by far, the leading causes of death in the EU. (europa.eu)
  • the most common causes of death from diseases of the circulatory system are ischaemic heart diseases and cerebrovascular diseases. (europa.eu)
  • The quartet was also soon ensconced in Tampa's imminently famous Morrisound Studios with future premier death metal producer Scott Burns (lots of firsts in this story, huh? (apple.com)
  • The "my death versus your death" concept emphasizes the irrational belief that while "your death" is a certainty, an exemption may be made in "my case. (britannica.com)
  • Ashcroft's report also emphasizes the many procedural safeguards the federal government has put in place to ensure that race does not affect the imposition of death, including instructions to jurors, appointment of competent defense counsel and centralized review in the Justice Department of all federal death-penalty cases. (thenation.com)
  • There are more and more academic studies on death penalty in China, however CADP emphasizes social action rather than academic research alone. (archive.org)
  • The term programmed cell death derived originally from developmental and embryonic observations, and it emphasizes the idea that specific genes regulate the death of cells. (encyclopedia.com)
  • Garza's case raised these questions in a particularly direct way, because the study found that the federal death penalty is disproportionately sought and obtained against black and Hispanic defendants, and disproportionately meted out in a handful of states, Texas the leader among them. (thenation.com)
  • Ashcroft stresses that of all federal cases that could have been tried as capital cases, the Attorney General actually authorized the death penalty more often against white defendants than minority defendants. (thenation.com)
  • Providing legal defense or legal aid to the defendants in death penalty cases, especially in cases that are wrongly sentenced, that involve the use of torture or that have procedural defects, or that in which the defendant suffers from mental illnesses. (archive.org)
  • promoting legal reform and ultimately abolish death penalty in China. (archive.org)
  • To abolish death penalty in China requires long-term commitment, yet there are some pressing work needs to be addressed. (archive.org)
  • New Jersey's state assembly yesterday voted 44-36 to abolish the death penalty - the first state to do so since Iowa and West Virginia scrapped the punishment in 1965. (theregister.co.uk)
  • This past December, President Clinton put off Garza's execution date because a Justice Department study had raised serious questions about racial, ethnic and geographical disparities in the administration of the federal death penalty. (thenation.com)
  • Ashcroft issued a supplementary report, but it contained no new relevant information and failed to undertake the analysis required to determine whether the federal death-penalty disparities were attributable to bias. (thenation.com)
  • Thanatology (from Greek thanatos, "death") as a professional discipline gathered momentum following the publication of several subject-related books including The Meaning of Death (1959), edited by Herman Feifel, and The Psychology of Death (1972) by Robert Kastenbaum and Ruth Aisenberg. (britannica.com)
  • And Texas, a single state, accounts for nearly a third of all federal death-row inmates. (thenation.com)
  • Although cancer deaths have declined for both Whites and African Americans/Blacks living in the United States, African Americans/Blacks continue to suffer the greatest burden for each of the most common types of cancer. (cancer.gov)
  • Over the course of more than a decade and seven increasingly accomplished albums, Chuck Schuldiner, the architect behind the ubiquitous Death, became a bona fide heavy metal icon. (apple.com)
  • Indeed, while the savagely raw aggression contained in Death's first three albums proved crucial to spearheading the first generation of death metal bands, the astounding musicianship and increasingly sophisticated songwriting found on their later-day efforts surely influenced even more groups to explore the limits of extreme metal's most progressive outposts. (apple.com)
  • The increasing professionalization of death management meant that death and its accompanying rituals increasingly occurred outside the home, in hospitals and funeral homes. (encyclopedia.com)
  • A Hispanic man sentenced to death in Texas for three drug-related murders, he is scheduled to be executed on June 19. (thenation.com)
  • The sanction of death for the punishment of a murder in the United States has declined in recent years. (aclu.org)
  • Beets was convicted of capital murder in the 1983 death of her fifth husband, retired Dallas fire captain Jimmy Don Beets. (mysanantonio.com)
  • Death Rituals är det amerikanska death metal -bandet Six Feet Unders tionde fullängdsalbum, som gavs ut den 10 november 2008 av Metal Blade Records . (wikipedia.org)
  • As the Gaza offensive of 2009 demonstrates, this new death hierarchy has opened Israel to global criticism. (jhu.edu)
  • Prosecuting a death penalty case is extremely expensive for a state and drains money that could be used for education and social programs. (aclu.org)
  • Russian oligarch Boris Berezovsky was not killed by chemical or radioactive material, British police said today, but still calling the 67-year-old's death unexplained. (yahoo.com)
  • A year after Litvinenko's death, Berezovsky said Scotland Yard had warned him about a plot on his life , but British police never confirmed his claim. (yahoo.com)
  • Six Baltimore police officers were arrested and posted bail Friday, after the chief prosecutor for the eastern U.S. city of Baltimore announced criminal charges in the death of a 25-year-old man earlier this month. (voanews.com)
  • The root of the problem is that there simply is no fair and objective way to isolate, from among the approximately 20,000 homicides that take place each year, the 100 or so that will lead to the ultimate punishment of death. (thenation.com)
  • It's been over a year since I first experienced a Facebook friend death, and I still find myself logging on to browse the accounts of the deceased. (forbes.com)
  • A longer, chronic toxicity test will allow enough time for these effects to appear in an organism and for them to lead to ecological death. (wikipedia.org)
  • defining death is much more complicated than it appears, and it's getting harder to define all the time. (newscientist.com)
  • He was thrown into prison, and sentenced to death, but he prevailed on his gaoler to permit him to leave the dungeon for a time, that he might see his wife. (upenn.edu)
  • I just finished Thich Nhat Hanh's No Death No Fear, and I liked it, but I feel such a hard time getting around the idea of continuance - it's too much for my materialist mind. (mail-archive.com)
  • These cells' demise is genetically programmed and when their time comes, death is orchestrated by the regulated expression of dozens of genes. (newscientist.com)
  • Come to think of it, more obituary pages would mean more space for paid death notices, too, so this might actually be a way to reverse the great newspaper-circulation slide and beef up ad pages at the same time. (slate.com)
  • Also, while Seven Churches represented something of an unplanned transition between thrash and death metal, Scream Bloody Gore more clearly defined the new offshoot's true essence for the first time. (apple.com)
  • Pope John Paul was 84 years old at the time of his death. (ewtn.com)
  • She also said she would open up death chambers to the media for the first time - though not on execution dates - to expose to public scrutiny the mechanics of a process that has long been shrouded in secrecy. (smh.com.au)
  • Apart from the physical exposure to death, the willingness of adults to discuss death with children and the ways in which death is discursively managed in interactions with children have changed over time in Western cultures. (encyclopedia.com)
  • Each time a person was sentenced to death, Bush received from his legal counsel a document summarizing the facts of the case, usually on the morning of the day scheduled for the execution, and was then briefed on those presumed facts by his counsel. (villagevoice.com)
  • According to the experience of a number of countries around the globe which have already abolished death penalties , this work requires great efforts ranging from legal, political, cultural and ideal front, long-time communication of ideas and thoughts, and specific social movements. (archive.org)
  • At the time, his death was attributed to a heart attack, but later investigations found multiple prescription drugs in his system, including the opioid codeine. (cnn.com)
  • Also, the papers don't mention it, but this story should give pause to anyone who thinks the death penalty is a deterrent. (slate.com)
  • In addition, this issue also includes several reviews on tangential topics, such as viral hijacking of host caspases, metacaspase functions, non-lethal functions of BCL-2 family proteins, and alternative, caspase-independent developmental cell death pathways. (nature.com)
  • In developmental situations, death frequently, if surprisingly, requires the synthesis of new proteins, perhaps including those involved in killing the cell. (encyclopedia.com)
  • The second concept, "partial deaths versus total extinction" stresses the belief that by experiencing the bereavement following the deaths of friends and relatives, a person is brought as close as possible to realizing "partial death. (britannica.com)
  • The EU Member States with the highest standardised death rates from ischaemic heart disease were Lithuania, Latvia, Slovakia and Hungary - all close to or above 400 deaths per 100 000 inhabitants in 2015. (europa.eu)
  • in Estonia, Latvia and Denmark, as well as in Serbia, death rates were very close to this level. (europa.eu)
  • A former " American Idol " contestant has revealed that she escaped a close brush with death. (nypost.com)
  • Japan's justice minister, a foe of capital punishment, has announced a review of the death penalty after witnessing the first executions since her centre-left government took power in 2009. (smh.com.au)
  • Parnia thinks of these experiences as actual-death experiences as opposed to near-death experiences. (npr.org)
  • Chatterbox thinks the death of the just-folks obit has the potential to become a significant issue for the baby boom generation. (slate.com)
  • In studies from a total of 7 cities, the risk of death among homeless women was greater than that among women in the general population by a factor of 4.6 to 31.2 in the younger age group and 1.0 to 2.0 in the older age group. (cmaj.ca)
  • In its review of death penalty expenses, the State of Kansas concluded that capital cases are 70 percent more expensive than comparable non-death penalty cases, including the costs of incarceration. (aclu.org)
  • While the review did not pinpoint any biochemical mechanism that may be behind the increased death risk, it may be that "by eliminating free radicals from our organism, we interfere with some essential defensive mechanisms," the study concluded. (reuters.com)
  • Upon issuance of a local (foreign) death certificate, the nearest embassy or consulate may prepare a Consular Report of the Death of an American Abroad. (state.gov)
  • When a death has been registered in a civil registry , a death certificate may be issued. (wikipedia.org)
  • Such death certificate may be required in a number of legal situations, such as applying for probate , claiming some benefits or making an insurance claim, etc. (wikipedia.org)
  • If a change needs to be made to a death certificate, please visit the Correct/Amend a Death Certificate page of the Vital Records website for more information. (in.gov)
  • Further information about death certificates can be found on the Vital Records pages Who Can Obtain a Death Certificate , Apply for a Death Certificate , and Correct/Amend a Death Certificate , or by following the links provided above. (in.gov)
  • This photo released by the Los Angeles County Registrar/County Clerk shows page 2 of actress Natalie Wood's death certificate. (yahoo.com)
  • Authorities amended Wood's death certificate on Aug. 1, 2012 to reflect some of the lingering questions about how the actress died in the waters off Catalina Island in November 1981. (yahoo.com)
  • A new report shows coroner 's officials amended Natalie Wood's death certificate based on unanswered questions about bruises on her upper body. (yahoo.com)
  • Spring Valley (N.Y.) police seek clues in the death of a newborn along Maple Avenue near North Myrtle Avenue on Nov. 1, 2013. (usatoday.com)
  • Michael Cushing, a personal injury attorney at Cushing Law Offices , recently settled a wrongful death lawsuit (Case No. 12 L 897) on behalf of the family of a woman who died from drug intoxication that included Fentanyl, and a combination of other drugs. (prweb.com)
  • The wrongful death lawsuit, Fred Saltzman, as Special Administrator of the Estate of Tenessa Vincent, deceased v. Embassy Holdings, LLC, et al. (prweb.com)