Cations
Cations, Divalent
Cations, Monovalent
Organic Cation Transport Proteins
Organic Cation Transporter 1
Magnesium
TRPM Cation Channels
Calcium
Sodium
TRPC Cation Channels
Ion Channels
Potassium
Manganese
Cation Transport Proteins
Hydrogen-Ion Concentration
Membrane Potentials
Rubidium
Strontium
Lithium
TRPV Cation Channels
Cation Exchange Resins
Cesium
Metals, Alkali
Ion Transport
Cell Membrane Permeability
Cyclic Nucleotide-Gated Cation Channels
Barium
Ions
Ion Channel Gating
Patch-Clamp Techniques
Quaternary Ammonium Compounds
Edetic Acid
Biological Transport
Flufenamic Acid
Metals
Calcium Channels
Binding Sites
Lanthanum
Cobalt
Molecular Sequence Data
Adenosine Triphosphate
Cell Membrane
Zinc
Catecholamine Plasma Membrane Transport Proteins
Amino Acid Sequence
Biological Transport, Active
Osmolar Concentration
Electrophysiology
Nickel
Salts
Gadolinium
Temperature
Models, Molecular
TRPP Cation Channels
Antiporters
Sodium-Potassium-Exchanging ATPase
Substrate Specificity
Cadmium
Metals, Rare Earth
Metals, Alkaline Earth
Permeability
Ouabain
Potassium Chloride
Oocytes
Calcium Chloride
Tromethamine
Protons
Chelating Agents
Ion Exchange
Rabbits
Transient Receptor Potential Channels
Ionophores
Protein Binding
1-Methyl-4-phenylpyridinium
Gramicidin
Potassium Channels
Protein Conformation
Erythrocytes
Valinomycin
Membrane Proteins
Carrier Proteins
Amiloride
Thermodynamics
Escherichia coli
Electrochemistry
Dose-Response Relationship, Drug
Cesium Isotopes
Onium Compounds
Molecular Structure
Models, Chemical
Cells, Cultured
Kidney
Lipid Bilayers
Mutation
Water
Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
Sodium Channels
Spermidine
Adenosine Triphosphatases
Equilibrative Nucleoside Transport Proteins
Cattle
Models, Biological
Spermine
Chromatography, Ion Exchange
Choline
Structure-Activity Relationship
Organophosphorus Compounds
Calcimycin
Base Sequence
Calcium Channel Blockers
Lasalocid
Tetraphenylborate
Extracellular Space
Receptors, Purinergic P2X7
Binding, Competitive
Bentonite
Meglumine
Potassium Isotopes
Magnetic Resonance Spectroscopy
Mathematics
Sodium Isotopes
Membrane Transport Modulators
Fluorescent Dyes
Potassium-Hydrogen Antiporters
Ion Exchange Resins
Buffers
Xenopus
Sequence Homology, Amino Acid
Nigericin
Receptors, Purinergic P2
DNA
Mutagenesis, Site-Directed
Nucleic Acid Conformation
Bromides
Guinea Pigs
Melibiose
Neurons
Free Radicals
Cloning, Molecular
Ruthenium Red
Receptors, Purinergic P2X4
Protein Structure, Tertiary
Mercury
Hydrogen
Fura-2
Acid Sensing Ion Channels
Spectrophotometry
Ion Pumps
Catalysis
Terbium
Calcium Signaling
Carnitine
Membranes, Artificial
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid
Solutions
Sodium Radioisotopes
Sodium-Hydrogen Antiporter
Silver
Rubidium Radioisotopes
Calixarenes
Spectrophotometry, Ultraviolet
Thapsigargin
Crystallography, X-Ray
Electrolytes
Receptors, Purinergic P2X
Oxidation-Reduction
Electrophoresis, Polyacrylamide Gel
The contribution of adjacent subunits to the active sites of D-3-phosphoglycerate dehydrogenase. (1/3963)
D-3-Phosphoglycerate dehydrogenase (PGDH) from Escherichia coli is allosterically inhibited by L-serine, the end product of its metabolic pathway. Previous results have shown that inhibition by serine has a large effect on Vmax and only a small or negligible effect on Km. PGDH is thus classified as a V-type allosteric enzyme. In this study, the active site of PGDH has been studied by site-directed mutagenesis to assess the role of certain residues in substrate binding and catalysis. These consist of a group of cationic residues (Arg-240, Arg-60, Arg-62, Lys-39, and Lys-141') that potentially form an electrostatic environment for the binding of the negatively charged substrate, as well as the only tryptophan residue found in PGDH and which fits into a hydrophobic pocket immediately adjacent to the active site histidine residue. Interestingly, Trp-139' and Lys-141' are part of the polypeptide chain of the subunit that is adjacent to the active site. The results of mutating these residues show that Arg-240, Arg-60, Arg-62, and Lys-141' play distinct roles in the binding of the substrate to the active site. Mutants of Trp-139' show that this residue may play a role in stabilizing the catalytic center of the enzyme. Furthermore, these mutants appear to have a significant effect on the cooperativity of serine inhibition and suggest a possible role for Trp-139' in the cooperative interactions between subunits. (+info)The stimulatory effects of Hofmeister ions on the activities of neuronal nitric-oxide synthase. Apparent substrate inhibition by l-arginine is overcome in the presence of protein-destabilizing agents. (2/3963)
A variety of monovalent anions and cations were effective in stimulating both calcium ion/calmodulin (Ca2+/CaM)-independent NADPH-cytochrome c reductase activity of, and Ca2+/CaM-dependent nitric oxide (NO.) synthesis by, neuronal nitric oxide synthase (nNOS). The efficacy of the ions in stimulating both activities could be correlated, in general, with their efficacy in precipitating or stabilizing certain proteins, an order referred to as the Hofmeister ion series. In the hemoglobin capture assay, used for measurement of NO. production, apparent substrate inhibition by L-arginine was almost completely reversed by the addition of sodium perchlorate (NaClO4), one of the more effective protein-destabilizing agents tested. Examination of this phenomenon by the assay of L-arginine conversion to L-citrulline revealed that the stimulatory effect of NaClO4 on the reaction was observed only in the presence of oxyhemoglobin or superoxide anion (generated by xanthine and xanthine oxidase), both scavengers of NO. Spectrophotometric examination of nNOS revealed that the addition of NaClO4 and a superoxide-generating system, but neither alone, prevented the increase of heme absorption at 436 nm, which has been attributed to the nitrosyl complex. The data are consistent with the release of autoinhibitory NO. coordinated to the prosthetic group of nNOS, which, in conjunction with an NO. scavenger, causes stimulation of the reaction. (+info)Screening for mutations of the cationic trypsinogen gene: are they of relevance in chronic alcoholic pancreatitis? (3/3963)
BACKGROUND: In hereditary pancreatitis mutations of exons 2 (N21I) and 3 (R117H) of the cationic trypsinogen gene have been described. AIMS: To investigate whether the same mutations can also be found in patients with chronic alcoholic pancreatitis. METHODS: Leucocyte DNA was prepared from 23 patients with chronic alcoholic pancreatitis, 21 with alcoholic liver cirrhosis, 34 individuals from seven independent families with hereditary pancreatitis, and 15 healthy controls. DNA was also obtained from pancreatic tissue (n=7) and from pancreatic juice (n=5) of patients suffering from chronic alcoholic pancreatitis. R117H was detected by restriction digestion with Afl III. N21I was identified by an allele specific polymerase chain reaction (PCR). RESULTS: R117H was detected in four families with hereditary pancreatitis. The N21I mutation was identified in three families. All mutations were confirmed by sequencing of the corresponding DNAs. In patients with chronic alcoholic pancreatitis neither the exon 2 nor exon 3 mutations were present in blood leucocytes, pancreatic juice, or pancreatic tissue. DNA of the patients with alcoholic liver cirrhosis as well as all controls was of wild type. CONCLUSIONS: The allele specific PCR may be used to screen for the N21I mutation of cationic trypsinogen. Both trypsinogen mutations were found in hereditary pancreatitis but do not seem to be major pathogenic factors in chronic alcoholic pancreatitis. (+info)Location of a cation-binding site in the loop between helices F and G of bacteriorhodopsin as studied by 13C NMR. (4/3963)
The high-affinity cation-binding sites of bacteriorhodopsin (bR) were examined by solid-state 13C NMR of samples labeled with [3-13C]Ala and [1-13C]Val. We found that the 13C NMR spectra of two kinds of blue membranes, deionized (pH 4) and acid blue at pH 1.2, were very similar and different from that of the native purple membrane. This suggested that when the surface pH is lowered, either by removal of cations or by lowering the bulk pH, substantial change is induced in the secondary structure of the protein. Partial replacement of the bound cations with Na+, Ca2+, or Mn2+ produced additional spectral changes in the 13C NMR spectra. The following conclusions were made. First, there are high-affinity cation-binding sites in both the extracellular and the cytoplasmic regions, presumably near the surface, and one of the preferred cation-binding sites is located at the loop between the helix F and G (F-G loop) near Ala196, consistent with the 3D structure of bR from x-ray diffraction and cryoelectron microscopy. Second, the bound cations undergo rather rapid exchange (with a lifetime shorter than 3 ms) among various types of cation-binding sites. As expected from the location of one of the binding sites, cation binding induced conformational alteration of the F-G interhelical loop. (+info)Modulation of slow inactivation in human cardiac Kv1.5 channels by extra- and intracellular permeant cations. (5/3963)
1. The properties and regulation of slow inactivation by intracellular and extracellular cations in the human heart K+ channel hKv1.5 have been investigated. Extensive NH2- and COOH-terminal deletions outside the central core of transmembrane domains did not affect the degree of inactivation. 2. The voltage dependence of steady-state inactivation curves of hKv1.5 channels was unchanged in Rb+ and Cs+, compared with K+, but biexponential inactivation over 10 s was reduced from approximately 100 % of peak current in Na+ to approximately 65 % in K+, approximately 50 % in Rb+ and approximately 30 % in Cs+. This occurred as a result of a decrease in both fast and slow components of inactivation, with little change in inactivation time constants. 3. Changes in extracellular cation species and concentration (5-300 mM) had only small effects on the rates of inactivation and recovery from inactivation (tau recovery approximately 1 s). Mutation of residues at a putative regulatory site at R487 in the outer pore mouth did not affect slow inactivation or recovery from inactivation of hKv1.5, although sensitivity to extracellular TEA was conferred. 4. Symmetrical reduction of both intra- and extracellular cation concentrations accelerated and augmented both components of inactivation of K+ (Kd = 34.7 mM) and Cs+ (Kd = 20.5 mM) currents. These effects could be quantitatively accounted for by unilateral reduction of intracellular K+ (K+i) (Kd = 43.4 mM) or Cs+i with constant 135 mM external ion concentrations. 5. We conclude that inactivation and recovery from inactivation in hKv1.5 were not typically C-type in nature. However, the ion species dependence of inactivation was still closely coupled to ion permeation through the pore. Intracellular ion modulatory actions were more potent than extracellular actions, although still of relatively low affinity. These results suggest the presence of ion binding sites capable of regulating inactivation located on both intracellular and extracellular sides of the pore selectivity filter. (+info)Gating current studies reveal both intra- and extracellular cation modulation of K+ channel deactivation. (6/3963)
1. The presence of permeant ions can modulate the rate of gating charge return in wild-type human heart K+ (hKv1.5) channels. Here we employ gating current measurements in a non-conducting mutant, W472F, of the hKv1.5 channel to investigate how different cations can modulate charge return and whether the actions can be specifically localized at the internal as well as the external mouth of the channel pore. 2. Intracellular cations were effective at accelerating charge return in the sequence Cs+ > Rb+ > K+ > Na+ > NMG+. Extracellular cations accelerated charge return with the selectivity sequence Cs+ > Rb+ > Na+ = NMG+. 3. Intracellular and extracellular cation actions were of relatively low affinity. The Kd for preventing slowing of the time constant of the off-gating current decay (tau off) was 20.2 mM for intracellular Cs+ (Cs+i) and 358 mM for extracellular Cs+ (Cs+o). 4. Both intracellular and extracellular cations can regulate the rate of charge return during deactivation of hKv1.5, but intracellular cations are more effective. We suggest that ion crystal radius is an important determinant of this action, with larger ions preventing slowing more effectively. Important parallels exist with cation-dependent modulation of slow inactivation of ionic currents in this channel. However, further experiments are required to understand the exact relationship between acceleration of charge return and the slowing of inactivation of ionic currents by cations. (+info)Phospholipid-subclass-specific partitioning of lipophilic ions in membrane-water systems. (7/3963)
Herein, we systematically investigate phospholipid-subclass-specific alterations in the partitioning of both cationic and anionic amphiphiles to identify the importance of ester, ether and vinyl ether linkages at the sn-1 position of phospholipids in the partitioning of charged amphiphiles. The results demonstrated that the membrane-water partition coefficient of a prototypic cationic amphiphile (i.e. 3,3'-dipropylthiadicarbocyanine iodide) was approximately 2.5 times higher in membranes comprised of plasmenylcholine in comparison with membranes comprised of either phosphatidylcholine or plasmanylcholine. In striking contrast, the membrane-water partition coefficient of a prototypic anionic amphiphile [i.e. bis-(1,3-dibutylbarbituric acid)trimethine oxonol] in membranes comprised of plasmenylcholine was approximately 2.5 times lower than that manifest in membranes comprised of phosphatidylcholine or plasmanylcholine. Utilizing theseexperimentally determined partition coefficients,the relative membrane dipole potential of membranes comprised of plasmenylcholine was calculated and found to be approximately 25 mV lower than in membranes comprised of phosphatidylcholine or plasmanylcholine. This lower membrane dipole potential in membranes comprised of plasmenylcholine is equivalent to the membrane potential induced by incorporation of approximately 25 mol% of anionic phospholipids in membranes comprised of phosphatidylcholine. Collectively, these results demonstrate that phospholipid-subclass-specific differences in the membrane dipole potential contribute to alterations in the partitioning of lipophilic ions in membrane bilayers comprised of distinct phospholipid subclasses. Moreover, they suggest that these physicochemical differences can be exploited to facilitate the targeting of charged lipophilic drugs to specific cells and subcellular membrane compartments. (+info)Partitioning of triphenylalkylphosphonium homologues in gel bead-immobilized liposomes: chromatographic measurement of their membrane partition coefficients. (8/3963)
Unilamellar liposomes of small or large size, SUVs and LUVs, respectively, were stably immobilized in the highly hydrophilic Sepharose 4B or Sephacryl S-1000 gel beads as a membrane stationary phase for immobilized liposome chromatography (ILC). Lipophilic cations of triphenylmethylphosphonium and tetraphenylphosphonium (TPP+) have been used as probes of the membrane potential of cells. Interaction of TPP+ and triphenylalkylphosphonium homologues with the immobilized liposomal membranes was shown by their elution profiles on both zonal and frontal ILC. Retardation of the lipophilic cations on the liposome gel bed was increased as the hydrophobicity of the cations increased, indicating the partitioning of lipophilic cations into the hydrocarbon region of the membranes. The cations did not retard on the Sepharose or Sephacryl gel bed without liposomes, confirming that the cations only interact with the immobilized liposomes. Effects of the solute concentration, flow rate, and gel-matrix substance on the ILC were studied. The stationary phase volume of the liposomal membranes was calculated from the volume of a phospholipid molecule and the amount of the immobilized phospholipid, which allowed us to determine the membrane partition coefficient (KLM) for the lipophilic cations distributed between the aqueous mobile and membrane stationary phases. The values of KLM were generally increased with the hydrophobicity of the solutes increased, and were higher for the SUVs than for the LUVs. The ILC method described here can be applied to measure membrane partition coefficients for other lipophilic solutes (e.g., drugs). (+info)Prevalence: Anemia, hemolytic, congenital is a rare disorder, affecting approximately 1 in 100,000 to 1 in 200,000 births.
Causes: The condition is caused by mutations in genes that code for proteins involved in hemoglobin synthesis or red blood cell membrane structure. These mutations can lead to abnormal hemoglobin formation, red blood cell membrane instability, and increased susceptibility to oxidative stress, which can result in hemolytic anemia.
Symptoms: Symptoms of anemia, hemolytic, congenital may include jaundice (yellowing of the skin and eyes), fatigue, weakness, pale skin, and shortness of breath. In severe cases, the condition can lead to life-threatening complications such as anemia, infections, and kidney failure.
Diagnosis: Anemia, hemolytic, congenital is typically diagnosed through a combination of physical examination, medical history, and laboratory tests, including blood smear examination, hemoglobin electrophoresis, and mutation analysis.
Treatment: Treatment for anemia, hemolytic, congenital depends on the specific underlying genetic cause and may include blood transfusions, folic acid supplements, antibiotics, and/or surgery to remove the spleen. In some cases, bone marrow transplantation may be necessary.
Prognosis: The prognosis for anemia, hemolytic, congenital varies depending on the specific underlying genetic cause and the severity of the condition. With appropriate treatment, many individuals with this condition can lead relatively normal lives, but in severe cases, the condition can be life-threatening.
Allan Cations
Hydrogen-bridged cations
Dihydrogen cation
Trihydrogen cation
Vinyl cation
Tropylium cation
Trifluoromethyl cation
Calcium:cation antiporter
Electroneutral cation-Cl
Cation-chloride cotransporter
Cation diffusion facilitator
2-Norbornyl cation
Cation channel superfamily
Cation-exchange capacity
Quaternary ammonium cation
Cation-π interaction
Organic cation transport protein
Calcium:cation antiporter-2
Cation channels of sperm
Base-cation saturation ratio
Nucleobase cation symporter-1
Polycystin cation channel family
Nucleobase cation symporter-2
Cation-anion radius ratio
Monovalent cation:proton antiporter-2
Monovalent cation:proton antiporter-3
Trimeric intracellular cation-selective channel
Monovalent cation:proton antiporter-1
Cation-dependent mannose-6-phosphate receptor
Non-selective cation channel-2 family
The Cations and Anions of Cyclobutanetetraone Poly(Phenylhydrazones) | NIST
Anomalous formation of trihydrogen cations from water on nanoparticles | Nature Communications
organic cation transport Antibodies | Invitrogen
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WikiGenes - TRPV1 - transient receptor potential cation...
Structure, function, and regional distribution of the organic cation transporter OCT3 in the kidney
Social Distancing Stay-cation and Summer Activities | Bridgeway Academy
Synthesis and cation distribution of copper-substituted spinel-related lithium ferrite - Open Research Online
The Sensitivity of Dielectric Signals to Cation Exchange Capacity in Shaly Sand Formations and Its Dependence on Salinity,...
Alamo Brand (A4000) Cation Water Softening Resin 1 CF Bag
- Isopure Water
Cation and Anion Standards | Reagecon
Cation Molecular Structure Affects Mobility and Transport of Electrolytes in Porous Carbons - A.J. Drexel Nanomaterials...
A novel ionic liquid for Li ion batteries - uniting the advantages of guanidinium and piperidinium cations - Lancaster EPrints
CATION CONCENTRATIONS OF PLANT TISSUES OF FRUIT-VEGETABLE CROPS AS AFFECTED BY THE EC OF THE EXTERNAL NUTRIENT SOLUTION AND BY...
The Ritz-Carlton Ras Al Khaimah - With New Revitalizing Treatments & Rejuvanting Spa-Cation Packages, Discover A Paradise Of...
Persistent subthreshold voltage-dependent cation single channels in suprachiasmatic nucleus neurons. - Inserm - Institut...
Effects of background cations on the fouling of polyethersulfone membranes by natural organic matter: Experimental and...
Solution-processed semitransparent CZTS thin-film solar cells via cation substitution and rapid thermal annealing | NTU...
Mathematical Model: Analyzing the Impli cations of the State as a Single Supplier of that Which it Demands for Payment of Taxes
Appli-ca-tions - Thermo-Bug®
Cation antiporters
Gabe's babes: Stay-cation!
Bae-Cation Dress - HouseofShimmer
rac-Me 2 Si(2-Me-4-t-Bu-C 5 H 2) 2 ZrMe + : an alkyl zirconocenium cation stabilized by steric shielding against interaction...
Citation Shark | My Bizz Cation
3 Southern Mom-cation Destinations
Cation Designs: Dabbling in Corsetry
Energy - Wuppertal Institute for Climate, Environment and Energy
Work Coat 22MK084 - Cation Workwear & Uniform
Organic8
- Regarded as the most important ion in interstellar chemistry, the trihydrogen cation, \({{\rm{H}}}_{{{3}}}^{+}\) , plays a vital role in the formation of water and many complex organic molecules believed to be responsible for life in our universe. (nature.com)
- Apart from traditional plasma discharges, recent laboratory studies have focused on forming the trihydrogen cation from large organic molecules during their interactions with intense radiation and charged particles. (nature.com)
- In these studies, usually a single organic molecule undergoes bond cleavage and bond formation in a two-step chemical process resulting in the creation of the trihydrogen cation. (nature.com)
- We examined in this study the expression of the potential-sensitive organic cation transporter OCT3 in the kidney. (nih.gov)
- The cloned transporter was found to be capable of mediating potential-dependent transport of a variety of organic cations including tetraethylammonium. (nih.gov)
- Human OCT3 was found to transport tetraethylammonium and a variety of other organic cations. (nih.gov)
- Particulate concentrates formed by intercalation of a polymer component into the galleries of the layered inorganic and organic homostructured layered cation exchange composition and to the use of the particulate concentrates for the preparation of cured polymer-inorganic nanolayer hybrid composite compositions are described. (nih.gov)
- Major parts of the spectra can be described by the model of the corresponding isolated organic cation, whereas high-emission energy peaks in the nitrogen K-edge XE spectra arise from electronic transitions involving hybrids of the molecular and atomic orbitals of the cations and halides, respectively. (kit.edu)
ZINC CATION1
- Your search for ZINC CATION did not return any results. (nih.gov)
Divalent cations1
- divalent cations enhanced inact. (cdc.gov)
Identifi2
- Differential Item Functioning in the Alcohol Use Disorders Identifi cation Test Funcionamiento Diferencial del Ítem en el Alcohol Use Disorders Identifi cation Test . (bvsalud.org)
- Identifi cation of outbreak strains of E . coli that cause lactose electrolyte-defi cient agar dip slides. (cdc.gov)
Hydrogen2
- Our results indicate that water to water hydrogen bonds are sensibly strengthened resulting in strong cooperative effects, which amount to ≈ 2 ${ \approx 2}$ â kcal/mol per hydrogen bond in the bare cavity and to larger values for the systems including the cations . (bvsalud.org)
- Approximate encapsulation, that is, surrounding the cation by a network of hydrogen bonds akin to the well known methane clathrate seems to be preferred by cations with smaller charge densities while microsolvation, that is, cluster structures having explicit Xâ ¯O contacts seem to be preferred by cations with larger charge densities which severely deform the cavity. (bvsalud.org)
Anions1
- Six cyclobutanetetraone poly (arylhydrazones) have been treated with acids and bases, and the structures of the resulting anions and cations studied by UV/visible absorption and NMR spectroscopy. (nist.gov)
Absorption1
- Baloxavir may bind to polyvalent cations resulting in decreased absorption. (medscape.com)
Calcium2
- On progressive addition of NaCl or KCl to solutions incorporating Ca2+ at concentrations of 5 mM or 12.5 mM (stoichiometric equivalence) the values of Tmax moved asymptotically towards those seen for the same concentrations of the monovalent cations in the absence of calcium, suggesting progressive displacement of site-bound Ca2+. (ucc.ie)
- Evageliou, V. I., Ryan, P. M. and Morris, E. R. (2018) 'Effect of monovalent cations on calcium-induced assemblies of kappa carrageenan', Food Hydrocolloids, In Press. (ucc.ie)
Bind1
- Previous studies have shown that kappa carrageenan helices bind K+ cations, but not Na+. (ucc.ie)
Stronger2
- Rissanen notes that the combination of data from the complexes in solution and as crystals makes a stronger case that the two cations interact like this. (chemistryworld.com)
- We find that the interaction of the methylammonium cation is stronger with the chlorine than with the iodine anion. (kit.edu)
Evidence1
- Evidence has been discovered that attractive forces exist between silver and iodonium cations. (chemistryworld.com)
Measurement2
- As a result, saturation models that account for clay will require the value of the formation cation exchange capacity (CEC), which is obtained from core measurement or inferred indirectly from the lithological interpretation. (onepetro.org)
- The other section is a very comprehensive list of all of the single element and multi element standards for both cation and anion measurement applicable to many industries, including Pharmaceuticals. (reagecon.com)
Stability3
- The effect of Na+, K+ and Ca2+ cations on the thermal stability and aggregation of kappa carrageenan double helices has been explored by differential scanning calorimetry (DSC). (ucc.ie)
- Our proposed interpretation is that Ca2+ cations "cement" the carrageenan helices together by binding directly between them, giving greater thermal stability, and thus greater hysteresis, than K+ cations which act indirectly by suppressing charge. (ucc.ie)
- The effects of the formal charge in the stability and bonding of water cavities when solvating a cation are studied here using [X(H2 O)20 ]q+ clusters starting with the well known 512 isomer of ( water )20 , placing a single mono, di, or trivalent Xq+ cation at the interior, and then optimizing and characterizing the resulting clusters. (bvsalud.org)
Free1
- In contrast to high-temperature synthetic routes, the present one leads to a Cu+ and Fe2+-cation free material, thereby optimizing its technological value. (open.ac.uk)
Charge1
- Ions with a positive charge are called cations. (medlineplus.gov)
Shown1
- the E-value for the Cation_ATPase_C domain shown below is 5.9e-48. (embl.de)
Radical cations2
- Role of radical cations in aromatic hydrocarbon carcinogenesis. (nih.gov)
- Deconstructive Functionalization of Unstrained Cycloalkanols via Electrochemically Generated Aromatic Radical Cations. (bvsalud.org)
Selectivity3
- Organic cation transporters collectively called OCTs belong to three gene families ( SLC22A1 OCT1, SLC22A2 OCT2, SLC22A3 OCT3, SLC22A4 OCTN1, SLC22A5 OCTN2, SLC29A4 PMAT, SLC47A1 MATE1, and SLC47A1 MATE2-K). OCTs transport structurally diverse drugs with overlapping selectivity. (nih.gov)
- An overview of functional properties, cation selectivity, location, and clinical impact of OCTs is provided. (nih.gov)
- Alkali cation selectivity of the wheat root high-affinity potassium transporter HKT1. (nih.gov)
Alkali1
- Homostructured, cation exchanged, layered compositions containing mixed onium and alkali metal, alkaline earth metal, protonated hydronium ions and mixtures thereof are described. (nih.gov)
Organic1
- Particulate concentrates formed by intercalation of a polymer component into the galleries of the layered inorganic and organic homostructured layered cation exchange composition and to the use of the particulate concentrates for the preparation of cured polymer-inorganic nanolayer hybrid composite compositions are described. (nih.gov)
Current2
- A sensitive mechanism for cation modulation of potassium current. (nih.gov)
- Heterologous manifestation studies indicate that TRPM3 mediates an outwardly rectifying cation current [15]. (flora2world.com)
Results1
- Your search for ZINC CATION did not return any results. (nih.gov)
Protocol1
- Because it was observed that the half maximal concentration of drugs to inhibit transport by OCTs ( IC 50 ) is dependent on the transported cation and its concentration, an advanced protocol for in vitro testing of drugs for interaction with OCTs is proposed. (nih.gov)