Polyphenolic compounds with molecular weights of around 500-3000 daltons and containing enough hydroxyl groups (1-2 per 100 MW) for effective cross linking of other compounds (ASTRINGENTS). The two main types are HYDROLYZABLE TANNINS and CONDENSED TANNINS. Historically, the term has applied to many compounds and plant extracts able to render skin COLLAGEN impervious to degradation. The word tannin derives from the Celtic word for OAK TREE which was used for leather processing.
Free Radical Scavengers
ESR study on the structure-antioxidant activity relationship of tea catechins and their epimers. (1/1387)The purpose of this study is to examine the relationship between the free radical scavenging activities and the chemical structures of tea catechins ((-)-epigallocatechin gallate (EGCG), (-)-epigallocatechin (EGC) and (-)-epicatechin (EC)) and their corresponding epimers ((-)-gallocatechin gallate (GCG), (-)-gallocatechin (GC) and (+)-catechin ((+)-C)). With electron spin resonance (ESR) we investigated their scavenging effects on superoxide anions (O-.2) generated in the irradiated riboflavin system, singlet oxygen(1O2) generated in the photoradiation-hemoporphyrin system, the free radicals generated from 2,2'-azobis(2-amidinopropane)hydrochloride (AAPH) and 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical. The results showed that the scavenging effects of galloylated catechins (EGCG and GCG) on the four free radicals were stronger than those of nongalloylated catechins (EGC, GC, EC, (+)-C), and the scavenging effects of EGC and GC were stronger than those of EC and (+)-C. Thus, it is suggested that the presence of the gallate group at the 3 position plays the most important role in their free radical-scavenging abilities and an additional insertion of the hydroxyl group at the 5' position in the B ring also contributes to their scavenging activities. Moreover, the corresponding phenoxyl radicals formed after the reaction with O-.2 were trapped by DMPO and the ESR spectra of DMPO/phenoxyl radical adducts were observed (aN=15.6 G and aHbeta=21.5 G). No significant differences were found between the scavenging effects of the catechins and their epimers when their concentrations were high. However, significant differences were observed at relatively low concentrations, and the lower their concentrations, the higher the differences. The scavenging abilities of GCG, GC and (+)-C were stronger than those of their corresponding epimers (EGCG, EGC and EC). The differences between their sterical structures played a more important role in their abilities to scavenge large free radicals, such as the free radicals generated from AAPH and the DPPH radical, than to scavenge small free radicals, such as O-.2 and 1O2, especially in the case with EGCG and GCG with more bulky steric hindrance. (+info)
Procyanidin oligomers selectively and intensively promote proliferation of mouse hair epithelial cells in vitro and activate hair follicle growth in vivo. (2/1387)We have previously reported that proanthocyanidins extracted from grape seeds possess growth-promoting activity toward murine hair epithelial cells in vitro and stimulate anagen induction in hair cycle progression in vivo. This report constitutes a comparison of the growth-promoting activity of procyanidin oligomers and the target cells of procyanidins in the skin. Results show that procyanidin dimer and trimer exhibit higher growth-promoting activity than the monomer. The maximum growth-promoting activity for hair epithelial cells with procyanidin B-2, an epicatechin dimer, reached about 300% (30 microM) relative to controls (= 100%) in a 5 d culture. Optimum concentration of procyanidin C-1, an epicatechin trimer, was lower than that of procyanidin B-2; the maximum growth-promoting activity of procyanidin C-1 was about 220% (3 microM). No other flavonoid compounds examined exhibit higher proliferative activities than the procyanidins. In skin constituent cells, only epithelial cells such as hair keratinocytes or epidermal keratinocytes respond to procyanidin oligomers. Topical application of 1% procyanidin oligomers on shaven C3H mice in the telogen phase led to significant hair regeneration [procyanidin B-2, 69.6% +/- 21.8% (mean +/- SD); procyanidin B-3, 80.9% +/- 13.0%; procyanidin C-1, 78.3% +/- 7.6%] on the basis of the shaven area; application of vehicle only led to regeneration of 41.7% (SD = 16.3%). In this paper, we demonstrate the hair-growing activity of procyanidin oligomers both in vitro and in vivo, and their potential for use as agents to induce hair growth. (+info)
Inhibition of benzo[a]pyrene-induced mutagenesis by (-)-epigallocatechin gallate in the lung of rpsL transgenic mice. (3/1387)Epigallocatechin gallate (EGCG) is a major water-soluble component of green tea. The antimutagenic activity of EGCG against benzo[a]pyrene (B[a]P)-induced mutations was assessed by using transgenic mice carrying the rpsL gene as a monitor of mutations. Seven-week-old male mice were given drinking water containing EGCG for 3 weeks. On day 7, mice were treated with a single i.p. injection of B[a]P (500 mg/kg body wt). Two weeks after the injection, the mutations in the rpsL gene were analyzed. B[a]P treatment resulted in an approximately 4-fold increase of mutation frequency at the rpsL gene in the lung. An approximately 60% reduction in the B[a]P-induced mutations in the lung was observed when mice were given EGCG at concentrations >0.005%. B[a]P-induced mutations mainly occurred at G:C basepairs in the several specific nucleotide sequences of the rpsL gene. These were AGG, CGG, CGT, TGG, TGC and GGT: all of them contained a guanine residue. Mutations seen similarly in the human Ki-ras codon 12 or p53 codons 157, 248, and 273 of lung tumor were also found in the rpsL gene, and the mutations were suppressed by the EGCG treatment. In conclusion, the antimutagenic effects of EGCG for B[a]P-induced mutagenesis in vivo suggest that drinking green tea may reduce the tumor-initiating potency of B[a]P in the lung. (+info)
Methylation of tea catechins by rat liver homogenates. (4/1387)Methylation of (-)-epigallocatechin (EGC), (-)-epicatechin gallate (ECg), and (-)-epigallocatechin gallate (EGCg) was carried out with a rat liver homogenate and S-adenosyl-L-methionine. A structural analysis of the reaction products by MS and NMR showed that 4'-O-methyl EGC, 4"-O-methyl ECg, and 4"-O-methyl EGCg had been formed from EGC, ECg, and EGCg, respectively. These results suggest that methylation may be one of the metabolic pathways to the catechins. (+info)
Epigallocathechin-3 gallate selectively inhibits the PDGF-BB-induced intracellular signaling transduction pathway in vascular smooth muscle cells and inhibits transformation of sis-transfected NIH 3T3 fibroblasts and human glioblastoma cells (A172). (5/1387)Enhanced activity of receptor tyrosine kinases such as the PDGF beta-receptor and EGF receptor has been implicated as a contributing factor in the development of malignant and nonmalignant proliferative diseases such as cancer and atherosclerosis. Several epidemiological studies suggest that green tea may prevent the development of cancer and atherosclerosis. One of the major constituents of green tea is the polyphenol epigallocathechin-3 gallate (EGCG). In an attempt to offer a possible explanation for the anti-cancer and anti-atherosclerotic activity of EGCG, we examined the effect of EGCG on the PDGF-BB-, EGF-, angiotensin II-, and FCS-induced activation of the 44 kDa and 42 kDa mitogen-activated protein (MAP) kinase isoforms (p44(mapk)/p42(mapk)) in cultured vascular smooth muscle cells (VSMCs) from rat aorta. VSMCs were treated with EGCG (1-100 microM) for 24 h and stimulated with the above mentioned agonists for different time periods. Stimulation of the p44(mapk)/p42(mapk) was detected by the enhanced Western blotting method using phospho-specific MAP kinase antibodies that recognized the Tyr204-phosphorylated (active) isoforms. Treatment of VSMCs with 10 and 50 microM EGCG resulted in an 80% and a complete inhibition of the PDGF-BB-induced activation of MAP kinase isoforms, respectively. In striking contrast, EGCG (1-100 microM) did not influence MAP kinase activation by EGF, angiotensin II, and FCS. Similarly, the maximal effect of PDGF-BB on the c-fos and egr-1 mRNA expression as well as on intracellular free Ca2+ concentration was completely inhibited in EGCG-treated VSMCs, whereas the effect of EGF was not affected. Quantification of the immunoprecipitated tyrosine-phosphorylated PDGF-Rbeta, phosphatidylinositol 3'-kinase, and phospholipase C-gamma1 by the enhanced Western blotting method revealed that EGCG treatment effectively inhibits tyrosine phosphorylation of these kinases in VSMCs. Furthermore, we show that spheroid formation of human glioblastoma cells (A172) and colony formation of sis-transfected NIH 3T3 cells in semisolid agar are completely inhibited by 20-50 microM EGCG. Our findings demonstrate that EGCG is a selective inhibitor of the tyrosine phosphorylation of PDGF-Rbeta and its downstream signaling pathway. The present findings may partly explain the anti-cancer and anti-atherosclerotic activity of green tea. (+info)
Involvement of endothelium/nitric oxide in vasorelaxation induced by purified green tea (-)epicatechin. (6/1387)The present study investigated the involvement of endothelial nitric oxide in relaxation induced by purified green tea (-)epicatechin in rat isolated mesenteric arteries. (-)Epicatechin caused both endothelium-dependent and -independent relaxation. NG-Nitro-L-arginine methyl ester (L-NAME, 100 microM) and methylene blue (10 microM) significantly attenuated (-)epicatechin-induced relaxation in endothelium-intact tissues. L-Arginine (1 mM) partially antagonized the effect of L-NAME. (-)Epicatechin-induced relaxation was inhibited by Rp-guanosine 3',5'-cyclic monophosphothioate triethylamine. In contrast, indomethacin and glibenclamide had no effect. (-)Epicatechin (100 microM) significantly increased the tissue content of cyclic GMP and NG-nitro-L-arginine (100 microM) or removal of the endothelium abolished this increase. (-)Epicatechin (100 microM) induced an increase in intracellular Ca2+ levels in cultured human umbilical vein endothelial cells. Iberiotoxin at 100 nM attenuated (-)epicatechin-induced relaxation in endothelium-intact arteries and this effect was absent in the presence of 100 microM L-NAME. In summary, (-)epicatechin-induced endothelium-dependent relaxation is primarily mediated by nitric oxide and partially through nitric oxide-dependent activation of iberiotoxin-sensitive K+ channels. In addition, there may be a causal link between increased Ca2+ levels and nitric oxide release in response to (-)epicatechin. (+info)
Suppression of extracellular signals and cell proliferation by the black tea polyphenol, theaflavin-3,3'-digallate. (7/1387)Previous studies in our laboratory have shown that the major green tea polyphenol, (-)-epigallocatechin-3-gallate (EGCG), suppressed autophosphorylation of epidermal growth factor (EGF) receptor induced by EGF in human A431 epidermoid carcinoma cells. In this study, we examined the inhibitory effects of black tea polyphenols, including theaflavin (TF-1), a mixture (TF-2) of theaflavin-3-gallate (TF-2a) and theaflavin-3'-gallate (TF-2b), theaflavin-3,3'-digallate (TF-3) and the thearubigin fraction on the autophosphorylation of the EGF and PDGF receptors in A431 cells and mouse NIH3T3 fibroblast cells, respectively. First, we examined the effects of these polyphenols on the proliferation of A431 and NIH3T3 cells. Both EGCG and TF-3 strongly inhibited the proliferation of A431 and NIH3T3 cells more than the other theaflavins did. In cultured cells with pre-treatment of tea polyphenol, TF-3 was stronger than EGCG on the reduction of EGF receptor and PDGF receptor autophosphorylation induced by EGF and PDGF, respectively. Other theaflavins slightly reduced the autophosphorylation of the EGF and PDGF receptors; furthermore, TF-3 could reduce autophosphorylation of the EGF receptor (or PDGF receptor) even with co-treatment with EGF (or PDGF) and TF-3, but EGCG was inactive under these conditions. In addition, TF-3 was stronger than EGCG in blocking EGF binding to its receptor. These results suggest that not only the green tea polyphenol, EGCG, but also the black tea polyphenol, TF-3, have an antiproliferative activity on tumor cells, and the molecular mechanisms of antiproliferation may block the growth factor binding to its receptor and thus suppress mitogenic signal transduction. (+info)
Apoptosis-inducing activity of polyphenol compounds derived from tea catechins in human histiolytic lymphoma U937 cells. (8/1387)Polyphenolic compounds derived from tea catechins were examined for apoptosis-inducing activity in human histiolytic lymphoma U937 cells. (-)-Epigallocatechin gallate, theasinensin D, compound OH-5, theaflavin, and theaflavin digallate induced apoptosis as evidenced by DNA ladder formation, its inhibition by a caspase inhibitor, and chromatin condensation. Theasinensin D was the most potent inducer and the data suggest the importance of the number and three dimensional localization of their phenolic groups in this activity. These apoptosis-inducible compounds may be useful as a cancer chemopreventive and chemotherapeutic agent. (+info)
The most common catechin isomer is (+)-catechin. The other stereoisomer is (-)-catechin or ent-catechin. The most common ... catechins (67 mg/kg). Catechins are diverse among foods, from peaches to green tea and vinegar. Catechins are found in barley ... catechin or DL-catechin and (+/-)-epicatechin or DL-epicatechin. Catechin and epicatechin are the building blocks of the ... 2R,3S)-Catechin-7-O-β-D-glucopyranoside can be isolated from barley (Hordeum vulgare L.) and malt. Epigeoside (Catechin-3-O- ...
... may refer to: Catechin-3-O-glucoside Catechin-3'-O-glucoside Catechin-4'-O-glucoside Catechin-5-O-glucoside ... Catechin-7-O-glucoside This set index page lists chemical compounds articles associated with the same name. If an internal link ...
... is a flavan-3-ol glycoside formed from catechin. Catechin-7-O-glucoside can be isolated from the ... catechin by cultured cells of Eucalyptus perriniana. Catechin-7-O-glucoside can be found in Paeoniae Radix, the crude drug made ... Catechin 7-O-β-d-glucopyranoside is found in rhubarb. This compound has an antioxidant activity leading to a cytoprotective ... Biotransformation of (+)-catechin by plant cultured cells of Eucalyptus perriniana. Otani S, Kondo Y, Asada Y, Furuya, Hamada, ...
It can also be formed from (+)-catechin by plant-cultured cells of Eucalyptus perriniana. Catechin glucosides: occurrence, ... Catechin 5-O-glucoside is a flavanol glucoside. It can be found in rhubarb and in the bark of Rhaphiolepis umbellata. ... catechin by plant-cultured cells of Eucalyptus perriniana. Shuichi Otani, Yoko Kondo, Yoshihisa Asada, Tsutomu Furuya, ...
... is a flavanol-anthocyanin adduct. Flavanol-anthocyanin adducts are formed during wine ageing ... Malvidin glucoside-ethyl-catechin on Yeast Metabolome Database Atanasova, Vessela; Fulcrand, Hélène; Cheynier, Véronique; ... Acetaldehyde-induced reactions yield ethyl-linked species such as malvidin glucoside-ethyl-catechin. This compound has a better ... Catechin in Model Solutions Containing Different Aldehydes". Journal of Food Science. 68 (2): 476-481. doi:10.1111/j.1365- ...
He proved the presence of catechin in cocoa beans in 1931. He showed in 1945 that luteic acid, a molecule present in the ... Adam, W. B.; Hardy, F.; Nierenstein, M. (1931). "The Catechin of the Cacao Bean". Journal of the American Chemical Society. 53 ... "Catechins isolated from tea leaves". Recueil des Travaux Chimiques des Pays-Bas. 58 (9): 805-830. doi:10.1002/recl.19390580907 ...
He proved the presence of catechin in cocoa beans in 1931. He also worked on milk and caseinogen. He reviewed the discovery of ... Adam, W. B.; Hardy, F.; Nierenstein, M. (1931). "The Catechin of the Cacao Bean". Journal of the American Chemical Society. 53 ...
... is a metabolite of the catechin degradation by Bradyrhizobium japonicum. The enzyme 3-carboxy- ... Waheeta Hopper and A. Mahadevan (1997). "Degradation of catechin by Bradyrhizobium japonicum". Biodegradation. 8 (3): 159-165. ...
... commonly occurs in nature as a biodegradation product of catechin, a natural phenol found in plants (e.g. by soil ... "Degradation of catechin by Bradyrhizobium japonicum". Biodegradation. 8 (3): 159-165. doi:10.1023/A:1008254812074. S2CID ...
Catechin was first isolated from the plant extract catechu, from which it derives its name. Heating catechin past its point of ... Catechin gallates are gallic acid esters of the catechins; an example is epigallocatechin gallate, which is commonly the most ... Catechin and epicatechin are epimers, with (-)-epicatechin and (+)-catechin being the most common optical isomers found in ... Only flavan-3-ols with an intact (epi)catechin moiety can be metabolized into 5-(3′/4′-dihydroxyphenyl)-γ-valerolactones (image ...
... contains catechin-7-O-glucoside. Inhibitors of Osteoclast Differentiation from Cephalotaxus koreana. Kee ...
Monoamine oxidase B
Geiparvarin Desmethoxyyangonin, a constituent of kava extract; modest affinity Catechin and epicatechin. ...
Sambandam, T.; Mahadevan, A. (1993). "Degradation of catechin and purification and partial characterization of catechin ... C. cupreum is able to degrade catechin. Agricultural interest in C. cupreum has arisen due to the ability of some strains to ...
Naturally occurring phenols
For example, ellagic acid is a dimer of gallic acid and forms the class of ellagitannins, or a catechin and a gallocatechin can ... An example of such molecules is catechin. Cavicularin is an unusual macrocycle because it was the first compound isolated from ... The aquatic plant Myriophyllum spicatum produces ellagic, gallic and pyrogallic acids and (+)-catechin. Alkylresorcinols can be ... catechin, allelopathic phenolic compounds inhibiting the growth of blue-green alga Microcystis aeruginosa. Phenolics, and in ...
Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E ... Randomized, placebo-controlled trial of green tea catechins for prostate cancer prevention. Cancer Prev Res (Phila). 2015;8(10 ... "Moving Toward the World's First Commercialization of Catechin; Mitsui Norin's Polyphenon E as a Main Ingredient in ... and then involves successive steps which concentrate the catechins thought to be responsible for the health benefits of green ...
Phloroglucinol carboxylic acid is a degradation product excreted by A. calcoaceticus grown on (+)-catechin as the sole source ... M. Arunachalam; N. Mohan; R. Sugadev; P. Chellappan; A. Mahadevan (11 June 2003). "Degradation of (+)-catechin by Acinetobacter ...
Phenolic content in tea
Catechins constitute about 25% of the dry mass of a fresh tea leaf, although total catechin content varies widely depending on ... are the main catechins metabolites found in humans after consumption of green tea infusions. Catechin monomer structures are ... Catechins are the largest type of flavonoids in growing tea leaves. According to a report released by USDA, in a 200-ml cup of ... Sensitive Determination of Catechins in Tea by HPLC . Retrieved 3 August 2013. Balentine DA, Harbowy ME, Graham HN (1998). "Tea ...
It is one of the main catechins metabolites found in humans after consumption of green tea infusions. It is also found in wine ... Pietta, P. G.; Simonetti, P.; Gardana, C.; Brusamolino, A.; Morazzoni, P.; Bombardelli, E. (1998). "Catechin metabolites after ...
... is one of the main catechins metabolites found in humans after consumption of green tea infusions. Oxidation of ... Pietta, P. G.; Simonetti, P.; Gardana, C.; Brusamolino, A.; Morazzoni, P.; Bombardelli, E. (1998). "Catechin metabolites after ...
... is one of the main catechins metabolites found in humans after consumption of green tea ... "Catechin metabolites after intake of green tea infusions". BioFactors. 8 (1-2): 111-8. doi:10.1002/biof.5520080119. PMID ...
... and stimulating thermogenesis due to the catechins that are present. Catechins are polyphenols that are a major component of ... Moreover, catechins in the brain play a major role in satiety. As weight loss depends on calorie intake, different kinds of ... In a human study conducted, 690 mg of catechins daily for 12 weeks reduced body fat, suggesting that green tea might be useful ... Matsumoto N, Ishigaki F, Ishigaki A, Iwashina H, Hara Y (April 1993). "Reduction of blood glucose levels by tea catechin". ...
... is one of the main catechins metabolites found in humans after consumption of green tea infusions. ... Pietta, P. G.; Simonetti, P.; Gardana, C.; Brusamolino, A.; Morazzoni, P.; Bombardelli, E. (1998). "Catechin metabolites after ...
It is the 3-O-methylation of catechin. It inhibits histidine decarboxylase in rats. Konturek, Stanislaw J; Ellen Kitler, Mary; ...
List of phytochemicals in food
Flavan-3-ols (flavanols) Catechins white tea, green tea, black tea, grapes, wine, apple juice, cocoa, lentils, black-eyed peas ... Catechin (+)-Gallocatechin (−)-Epicatechin (−)-Epigallocatechin (−)-Epigallocatechin gallate (EGCG) green tea. (−)-Epicatechin ...
April 2018). "Scientific opinion on the safety of green tea catechins". EFSA Journal. European Food Safety Authority. 16 (4): ... Particularly abundant flavanoids in foods are catechin (tea, fruits), hesperetin (citrus fruits), cyanidin (red fruits and ... epicatechin is more bitter and astringent than its chiral isomer catechin. In contrast, hydroxycinnamic acids do not have ... resulting in the withdrawal of a catechin-containing drug. Metabolism of polyphenols can result in flavonoid-drug interactions ...
Malvidin glucoside-ethyl-catechin on Yeast Metabolome Database Morata, A; González, C; Suárez-Lepe, JA (2007). "Formation of ... Malvidin glucoside-ethyl-catechin is a flavanol-anthocyanin adduct. Flavanol-anthocyanin adducts are formed during wine ageing ... In model solutions, colorless compounds, such as catechin, can give rise to new types of pigments. The first step is the ... Acetaldehyde-induced reactions yield ethyl-linked species such as malvidin glucoside-ethyl-catechin. This compound has a better ...
Thermoresponsive polymers in chromatography
Another group separated catechins using PNIPAAm. Since the separation of biological molecules such as proteins would be better ... Chikako Sakamoto; Yuji Okada; Hideko Kanazawa; Akihiko Kikuchi; Teruo Okano (2003). "Separation of catechins by temperature- ...
The DMACA reagent may be superior to the vanillin procedure for the detection of catechins. The DMACA reagent changes color ... catechin and (−)-epicatechin by 4-dimethylaminocinnamaldehyde reagent". Journal of Chromatography A. 1216 (20): 4485-91. doi: ...
C. edulis contains rutin, neohesperidin, hyperoside, catechin and ferulic acid; these contribute to the antibacterial ...
The fruits contain about 2% catechin-caffeine, theobromine and kolatin. They are roasted, pounded or chewed, and can be added ...
Catechin Analysis Kit - Support : SHIMADZU (Shimadzu Corporation)
Tea Catechins - WuLong Tea - Premium Chinese Slimming Tea
Tea Catechins Tea Catechins. Learn How Tea Catechins, Powerful Antioxidants, Can Aid in Weight Loss. Increased attention is ... The lower levels of LDL were also associated with the consumption of tea catechins. In the end, they saw that tea catechins may ... Tea Catechins *Tea catechins comprise 25% of the compounds that makes up a tea leaf. ... What are Tea Catechins?. Polyphenols are antioxidant compounds found in a variety of plant foods. These compounds have been ...
Functions of Catechin（
... 張傑克JACKCHANG 12/31/2022 Health Catechins are a type of polyphenol, which is a group of plant chemicals ... Research has suggested that catechins may have a number of potential health benefits. Some studies have found that catechins ... Catechins may also have a protective effect against certain types of cancer, including breast, prostate, and colon cancer.. It ... Catechins are found in a variety of plant-based foods, including tea, chocolate, wine, and certain fruits and vegetables. They ...
Catechin hydrate | CAS:7295-85-4 | Tocric
Powerful Catechins - Soul Performance Nutrition
In this article, we will delve into the scientific evidence on the effects of catechins ... Catechins are a type of flavonoid found in a variety of plant-based foods, including tea, cocoa, apples, and berries. They are ... Catechins have also been shown to have a positive effect on cholesterol levels. Some studies have found that catechins may help ... One of the most well-known catechins is epicatechin, which is found in high concentrations in green tea. Other catechins found ...
Integration of semi-|i|in vivo|/i| assays and multi-omics data reveals the effect of galloylated catechins on self-pollen tube...
In summary, galloylation of catechins and high levels of galloylated catechins are specifically involved in pollen tube ... Integration of semi-in vivo assays and multi-omics data reveals the effect of galloylated catechins on self-pollen tube ... Combined with multi-omics analysis, the results revealed the important role of galloylated catechins in self-pollen tube ...
Beneficial Effects of Green Tea Catechins on Female Reproductive Disor - M.O.O.
Results of a phase II randomized, double-blind, placebo-controlled trial of Polyphenon E in women with persistent high-risk HPV...
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Antioxidants | Free Full-Text | The Sorbus spp.-Underutilised Plants for Foods and Nutraceuticals: Review on Polyphenolic...
Catechin and epicatechin were the main flavonoid components in the samples of S. decora stembark , rootsock , but also ... Cat-catechin; QU-3-O-so-quercetin-3-O-β-sophoroside; QU-quercetin; KA-kaempferol; SX-sexangularetin. Unripe fruit (1), well ... catechin, epicatechin), anthocyanins (mainly cyanidin or pelargonidin glycosides), and proanthocyanidins [53,60]. In addition, ...
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Green Tea Catechins-EGCG , Teavigo. Teavigo is the highest quality green tea extract you can buy for weight loss and fat ... "The major catechin in green tea - known as Epigallocatechin-3-Gallate, or EGCg - is the main contributor to its many health ... The BRAND of Green Tea Catechins that I recommend is teavigo. Remember if you buy any other green tea extract most likely ... The powerful antioxidant properties of catechins, primarily EGCg, are widely demonstrated in animal and human research studies ...
Green tea extracts linked to healthier bones: Study
Related tags Catechin Compounds from green tea may lead to stronger bones by promoting bone formation, while also inhibiting ... "Effects of Tea Catechins, Epigallocatechin, Gallocatechin, and Gallocatechin Gallate, on Bone Metabolism". Authors: C.H. Ko, ... "Our study has provided the first laboratory evidence on the bone promotion effects of the green tea catechin EGC as was ... The other catechins were found to have a significantly weaker effect, said the researchers. ...
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Flavonoid Clipart Vector and Illustration. 402 Flavonoid clip art vector EPS images available to search from thousands of...
Chemical Database: Phosgene (EnvironmentalChemistry.com)
Green Tea Catechins Effectively Altered Hepatic Fibrogenesis in Rats by Inhibiting ERK and Smad1/2 Phosphorylation -...
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Clinical Hemorheology and Microcirculation - Volume 44, issue 3 - Journals - IOS Press
Abstract: We tested the in vivo and the in vitro effects of both Ligaria cuneifolia catechin- and quercetin-enriched fractions ... Effect of Ligaria cuneifolia catechin- and quercetin-enriched fractions on hemorheology and plasma cholesterol ... Keywords: Ligaria cuneifolia, catechin, quercetin, whole blood viscosity, plasmatic and biliary excretion of cholesterol, ... catechin (CLc; n = 5) and quercetin (QLc; n = 5), in a concentration equivalent to 0.60 mg/100 g body weight, and 2.3 mg/100 g ...
Defining the role of Parasutterella, a previously uncharacterized member of the core gut microbiota | The ISME Journal
Best Apple Cider Vinegar Gummies in 2023: 5 Picks for Optimal Health and Wellness - Chicago Magazine
Meeting the Challenge of Influenza Pandemic Preparedness in Developing Countries - Volume 15, Number 3-March 2009 - Emerging...
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Habitual chocolate consumption and risk of cardiovascular disease among healthy men and women | Heart
Catechin content highest in dark, bitter chocolate and lowest in light or milk chocolate. Chocolates & cocoa products also ... Chocolates are a rich source of catechins, a protective molecule against heart diseases, cancer, and other medical conditions. ... Chocolates are a rich source of catechins, a protective molecule against heart diseases, cancer, and other medical conditions. ...
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Epigallocatechin-3-GallaGallateEGCGFlavonoidPolyphenolsExtractAntioxidantPolyphenolInhibitCardiovascular healthCompoundsGreenConcentrationsCamelliaMechanismVitroHealthcareAdultsNaturallyNutritionConsumptionEffectMolecularChemicalsPreventionWeightFound in a varietyLevelsEffectsDiabetesHumanActivityBlood PressureBenefitsDietScoreResults
- The major catechin in green tea - known as Epigallocatechin-3-Gallate, or EGCg - is the main contributor to its many health benefits. (proteinfactory.com)
- Polyphenols and EGCG (Epigallocatechin gallate) are catechin antioxidant compounds found naturally in tea leaves. (wulongforlife.com)
- Other catechins found in green tea include epicatechin gallate (ECG), epicatechin 3-gallate (ECG3), and epigallocatechin (EGC). (soulperformancenutrition.com)
- The presumed active ingredient of green tea extract, epigallocatechin gallate (EGCG), was originally nominated by the National Cancer Institute for toxicity and carcinogenicity studies because it is the most abundant catechin in green tea extract, it was being investigated as a potential chemotherapeutic agent, and there was a lack of adequate information with regard to its toxicity. (nih.gov)
- The powerful antioxidant properties of catechins, primarily EGCg, are widely demonstrated in animal and human research studies. (proteinfactory.com)
- However, the NTP selected green tea extract [containing EGCG (48.4% by weight) and other green tea catechins] for study because human exposure is to green tea extract products that contain concentrated mixtures of various green tea catechins. (nih.gov)
- 5. Targeting receptor tyrosine kinases for chemoprevention by green tea catechin, EGCG. (nih.gov)
- Catechins are a type of flavonoid found in a variety of plant-based foods, including tea, cocoa, apples, and berries. (soulperformancenutrition.com)
- In conclusion, catechins are a type of flavonoid found in a variety of plant-based foods that have been shown to have a positive effect on blood flow and cardiovascular health. (soulperformancenutrition.com)
- Catechin, flavonoid, C15H14O6 molecule. (canstockphoto.com)
- Flavocoxid (Limbrel), a proprietary mixture of flavonoid molecules (baicalin and catechin), was tested against a traditional nonsteroidal anti-inflammatory drug, naproxen, for the management of the signs and symptoms of moderate osteoarthritis (OA) in humans. (nih.gov)
- An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms. (nih.gov)
- Green Tea Extract has numerous bioactive compounds, including polyphenols and catechins, which are known for their many health-supporting properties. (vitacost.com)
- Many herbal dietary supplements (HDS) contain green tea extract (GTE) and its component catechins, although their presence may not always be indicated on the product label. (nih.gov)
- In a study of healthy adults, daily supplementation with green tea extract containing catechins was found to significantly improve endothelial function and reduce blood pressure. (soulperformancenutrition.com)
- In a review of 14 randomized controlled trials, daily supplementation with green tea extract containing catechins was found to significantly reduce LDL cholesterol levels and increase HDL cholesterol levels. (soulperformancenutrition.com)
- We conducted a randomized, double-blind, placebo-controlled trial of Polyphenon E (decaffeinated and enriched green tea catechin extract) in women with persistent human papillomavirus (HPV) infection and low-grade cervical intraepithelial neoplasia (CIN1) to evaluate the potential of Polyphenon E for cervical cancer prevention. (nih.gov)
- Dried concentrated extracts from Camellia sinensis contain high amounts of catechins and are a popular source for green tea extract nutraceutical supplements and medicinal uses. (nih.gov)
- Abstract: DESCRIPTION (provided by applicant): Epidemiological data and experimental studies suggest that catechins of black or green tea with potent antioxidant activity have anticancer properties. (nih.gov)
- The polyphenol compound of tea catechins has drawn a lot of attention from the medical and research communities because of its link to reducing dietary lipid intake, giving it the ability to naturally reduce excess body fat through a plant form. (wulongforlife.com)
- Catechins are a type of polyphenol, which is a group of plant chemicals that help protect plants from pests and ultraviolet radiation. (jakchang.com)
- However, the exact molecular mechanism by which green tea catechins inhibit angiogenesis is not known. (nih.gov)
- Given our data we propose the following model: Green tea catechins inhibit angiogenesis through disruption of VE-cadherin/b-catenin complex. (nih.gov)
- b) Green tea catechins inhibit VEGF-induced PI3-kinase activation. (nih.gov)
- c) Green tea catechins inhibit VEGF-induced IL-8 activation, and that this inhibition is mediated through a decrease in the PI3-kinase/Akt pathway leading to decrease of NF-kB activation. (nih.gov)
- Catechins have been shown to inhibit the activity of enzymes involved in blood clot formation, such as thrombin and platelet aggregation. (soulperformancenutrition.com)
- Some studies have found that catechins may help improve cardiovascular health by lowering cholesterol levels and blood pressure. (jakchang.com)
- Improved cardiovascular health: Some studies have found that catechins may help lower cholesterol levels and blood pressure, which can help improve overall cardiovascular health. (jakchang.com)
- In this article, we will delve into the scientific evidence on the effects of catechins on blood flow and cardiovascular health. (soulperformancenutrition.com)
- It is worth noting that much of the research on the effects of catechins on blood flow and cardiovascular health has been conducted in animals or in cells in the laboratory, so more research is needed to understand their effects in humans. (soulperformancenutrition.com)
- However, the available evidence suggests that catechins may have a positive effect on blood flow and cardiovascular health. (soulperformancenutrition.com)
- More research is needed to fully understand the effects of catechins on blood flow and cardiovascular health in humans, but the available evidence is promising. (soulperformancenutrition.com)
- Because GTE and catechins have been implicated in human hepatotoxicity in several case reports, our objective was to determine whether catechins were present in HDS that were implicated in hepatotoxicity, even if not identified among the labeled ingredients, and whether these compounds could be associated with liver injury. (nih.gov)
- Tea catechins comprise 25% of the compounds that makes up a tea leaf. (wulongforlife.com)
- Incorporating catechins into your diet through the consumption of foods rich in these compounds, such as green tea, cocoa, apples, and berries, may have a positive impact on your overall health. (soulperformancenutrition.com)
- Specifically, we have found that green tea catechins' inhibition of angiogenesis in HMVEC is mediatedl: 1) by disruption of vascular endothelial (VE)-cadherin/b-catenin complex, and inhibition of Akt phosphorylation, a downstream molecular pathway implicated in angiogenesis, and 2) by inhibition of oxidative stress-induced interleukin (IL)-8 production, a potent angiogenic factor. (nih.gov)
- We propose to examine this model by testing the hypothesis: a) Green tea catechins disrupt VE-cadherin/ VEGF-receptor/ PI3-kinase complex formation. (nih.gov)
- One of the most well-known catechins is epicatechin, which is found in high concentrations in green tea. (soulperformancenutrition.com)
- These catechins are often referred to as the "ECGCs" because of their high levels in green tea. (soulperformancenutrition.com)
- In vitro data and pilot data suggest that green tea catechins may possess chemopreventive activity for cervical cancer and precursor lesions. (nih.gov)
- The BRAND of Green Tea Catechins that I recommend is teavigo. (proteinfactory.com)
- Catechin levels tended to be highest in products used for weight loss, although catechin concentrations were low in most products. (nih.gov)
- Integration of semi- in vivo assays and multi-omics data reveals the effect of galloylated catechins on self-pollen tube inhibition in Camellia oleifera . (bvsalud.org)
- One mechanism by which catechins may affect blood flow is through their effects on the endothelium, the inner lining of blood vessels. (soulperformancenutrition.com)
- Using our in vitro tube formation assay by the human microvascular endothelial cells (HMVEC), we have tested the inhibitory effect of catechins on vascular endothelial growth factor (VEGF} signaling during angiogenesis. (nih.gov)
- If you are considering taking catechin supplements, it is important to talk to a healthcare provider to determine the appropriate dosage and to ensure that it is safe for you. (jakchang.com)
- According to the U.S. Department of Agriculture (USDA), the average daily intake of catechins for adults is approximately 25-30 milligrams per day. (jakchang.com)
- Tea catechins work with other naturally occurring chemicals in the body to intensify levels of fat oxidation, or thermogenesis, the process by which heat is created in the body by burning fat. (wulongforlife.com)
- The 2005 study by the American Society for Clinical Nutrition , "Ingestion of a tea rich in catechins leads to a reduction in body fat and malondialdehyde-modified LDL in men," 1 investigated the effect of tea catechins (antioxidants) on body fat reduction and ability to reduce oxidized LDL cholesterol in the body. (wulongforlife.com)
- The lower levels of LDL were also associated with the consumption of tea catechins. (wulongforlife.com)
- Catechins may also have a protective effect against certain types of cancer, including breast, prostate, and colon cancer. (jakchang.com)
- Cancer prevention: Some studies have found that catechins may have a protective effect against certain types of cancer, including breast, prostate, and colon cancer. (jakchang.com)
- There is some evidence to suggest that catechins may also have a protective effect on the cardiovascular system by reducing the formation of blood clots, which can lead to heart attacks and strokes. (soulperformancenutrition.com)
- Catechins have also been shown to have a positive effect on cholesterol levels. (soulperformancenutrition.com)
- The other catechins were found to have a significantly weaker effect, said the researchers. (nutraingredients.com)
- However, the exact molecular target(s) of catechins on the inhibition of angiogenesis is yet to be elucidated. (nih.gov)
- Validation of this model would help in better understanding the specific molecular targets of tea catechins' induced inhibition of angiogenesis and in developing future studies to develop cost-effective strategies to fight against cancer. (nih.gov)
- Combined with multi-omics analysis , the results revealed the important role of galloylated catechins in self - pollen tube inhibition, and a possible molecular regulatory network mediated by UDP - glycosyltransferase (UGT) and serine carboxypeptidase -like (SCPL) was proposed. (bvsalud.org)
- There are many potential benefits to catechins, a group of plant chemicals that are found in a variety of plant-based foods. (jakchang.com)
- The recommended intake of catechins, a group of plant chemicals found in a variety of plant-based foods, depends on a number of factors, including age, gender, and overall health status. (jakchang.com)
- Catechins can contribute to cancer prevention not only by the reduction of tumor cell growth, migration and invasion, but also by the inhibition of angiogenesis, an obligatory process for tumor growth. (nih.gov)
- In the end, they saw that tea catechins may be useful in the prevention of body fat-related diseases and in the improvement of one's health. (wulongforlife.com)
- Recent research indicates that including catechins in your diet, by drinking Wu-Long tea for example, may lead to a decrease in body weight and a reduction of certain health issues. (wulongforlife.com)
- Weight loss: Some research has suggested that catechins may help with weight loss by increasing the body's metabolism and fat oxidation. (jakchang.com)
Found in a variety1
- Catechins are found in a variety of plant-based foods, including tea, chocolate, wine, and certain fruits and vegetables. (jakchang.com)
- Some studies have found that catechins may help to lower LDL (bad) cholesterol levels and increase HDL (good) cholesterol levels. (soulperformancenutrition.com)
- In summary, galloylation of catechins and high levels of galloylated catechins are specifically involved in pollen tube inhibition under self - pollination rather than cross- pollination , which provides a new understanding of SI in C. oleifera. (bvsalud.org)
- Anti-inflammatory effects: Catechins may have anti-inflammatory effects, which may help with the management of chronic conditions such as diabetes and certain types of cancer. (jakchang.com)
- "The present study illustrated that the tea catechins, EGC in particular, had positive effects on bone metabolism through a double process of promoting osteoblastic activity and inhibiting osteoclast differentiations," wrote the authors. (nutraingredients.com)
- Tomar un extracto de té negro y verde por vía oral no mejora los niveles de azúcar en la sangre en personas con diabetes. (medlineplus.gov)
- We assayed 97 HDS implicated in human hepatotoxicity for catechins. (nih.gov)
- Surface activity of cotton dust components: catechin (120809), rutin (153184), and gossypol (303457) was measured alone and with dipalmitoyl-lecithin (2644646) (DPL), the major constituent of lung surfactant. (cdc.gov)
- Catechins have been shown to improve the function of the endothelium, which may help to improve blood flow and lower blood pressure. (soulperformancenutrition.com)
- It is also important to get catechins from a variety of sources, rather than relying on supplements, as a varied and balanced diet is the best way to ensure adequate nutrient intake. (jakchang.com)
- Among patients with confirmed hepatotoxicity, there was no statistically significant association between the presence of catechin or the dose consumed and liver injury causality score, severity, or pattern of liver injury. (nih.gov)
- Although our results did not establish an association between GTE or catechins with hepatotoxicity, they highlight some of the many complexities and uncertainties that surround the attribution of drug-induced liver injury (DILI) to HDS. (nih.gov)