Catabolite Repression
Enzyme Repression
Galactosidases
Repressor Proteins
Phosphoenolpyruvate Sugar Phosphotransferase System
The bacterial sugar phosphotransferase system (PTS) that catalyzes the transfer of the phosphoryl group from phosphoenolpyruvate to its sugar substrates (the PTS sugars) concomitant with the translocation of these sugars across the bacterial membrane. The phosphorylation of a given sugar requires four proteins, two general proteins, Enzyme I and HPr and a pair of sugar-specific proteins designated as the Enzyme II complex. The PTS has also been implicated in the induction of synthesis of some catabolic enzyme systems required for the utilization of sugars that are not substrates of the PTS as well as the regulation of the activity of ADENYLYL CYCLASES. EC 2.7.1.-.
Gene Expression Regulation, Bacterial
Operon
Glucose
Carbon
Cyclic AMP Receptor Protein
A transcriptional regulator in prokaryotes which, when activated by binding cyclic AMP, acts at several promoters. Cyclic AMP receptor protein was originally identified as a catabolite gene activator protein. It was subsequently shown to regulate several functions unrelated to catabolism, and to be both a negative and a positive regulator of transcription. Cell surface cyclic AMP receptors are not included (CYCLIC AMP RECEPTORS), nor are the eukaryotic cytoplasmic cyclic AMP receptor proteins, which are the regulatory subunits of CYCLIC AMP-DEPENDENT PROTEIN KINASES.
Mutation
Succinates
Escherichia coli
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.
Tryptophanase
An enzyme that catalyzes the conversion of L-tryptophan and water to indole, pyruvate, and ammonia. It is a pyridoxal-phosphate protein, requiring K+. It also catalyzes 2,3-elimination and beta-replacement reactions of some indole-substituted tryptophan analogs of L-cysteine, L-serine, and other 3-substituted amino acids. (From Enzyme Nomenclature, 1992) EC 4.1.99.1.
Histidine Ammonia-Lyase
Transcription, Genetic
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Allantoin
Base Sequence
Enzyme Induction
Lactose
Promoter Regions, Genetic
beta-Galactosidase
Gene Expression Regulation, Fungal
Glycerol
Genes, Regulator
DNA-Binding Proteins
Transcription Factors
Nitrogen
Urocanate Hydratase
Culture Media
Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.
Lac Operon
Saccharomyces cerevisiae
Lyases
Pseudomonas putida
Cyclic AMP
Galactose
An aldohexose that occurs naturally in the D-form in lactose, cerebrosides, gangliosides, and mucoproteins. Deficiency of galactosyl-1-phosphate uridyltransferase (GALACTOSE-1-PHOSPHATE URIDYL-TRANSFERASE DEFICIENCY DISEASE) causes an error in galactose metabolism called GALACTOSEMIA, resulting in elevations of galactose in the blood.
Receptors, Cyclic AMP
Cell surface proteins that bind cyclic AMP with high affinity and trigger intracellular changes which influence the behavior of cells. The best characterized cyclic AMP receptors are those of the slime mold Dictyostelium discoideum. The transcription regulator CYCLIC AMP RECEPTOR PROTEIN of prokaryotes is not included nor are the eukaryotic cytoplasmic cyclic AMP receptor proteins which are the regulatory subunits of CYCLIC AMP-DEPENDENT PROTEIN KINASES.
Ammonia-Lyases
Carbohydrate Metabolism
Succinic Acid
A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
GATA Transcription Factors
Plasmids
Genetics, Microbial
Maltose
Carbohydrate Epimerases
Cellobiose
beta-Fructofuranosidase
Amino Acid Sequence
Hexokinase
An enzyme that catalyzes the conversion of ATP and a D-hexose to ADP and a D-hexose 6-phosphate. D-Glucose, D-mannose, D-fructose, sorbitol, and D-glucosamine can act as acceptors; ITP and dATP can act as donors. The liver isoenzyme has sometimes been called glucokinase. (From Enzyme Nomenclature, 1992) EC 2.7.1.1.
alpha-Amylases
Molecular Biology
Cloning, Molecular
Aspergillus nidulans
Acetoin Dehydrogenase
Fructose
Glucokinase
RNA, Bacterial
Regulon
Lactobacillus casei
Gene Expression Regulation
Acetate-CoA Ligase
Galactokinase
Operator Regions, Genetic
Recombinant Fusion Proteins
Genes
Gene Deletion
Binding Sites
Protein Binding
Gene Expression Regulation, Enzymologic
Saccharomyces cerevisiae Proteins
Artificial Gene Fusion
Protocatechuate-3,4-Dioxygenase
Carbon Isotopes
Leucine-Responsive Regulatory Protein
Anaerobiosis
alpha-Glucosidases
Genes, Reporter
RNA, Messenger
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Suppression, Genetic
Mutation process that restores the wild-type PHENOTYPE in an organism possessing a mutationally altered GENOTYPE. The second "suppressor" mutation may be on a different gene, on the same gene but located at a distance from the site of the primary mutation, or in extrachromosomal genes (EXTRACHROMOSOMAL INHERITANCE).
Aconitate Hydratase
Phosphotransferases (Nitrogenous Group Acceptor)
Xylosidases
A group of enzymes that catalyze the hydrolysis of alpha- or beta-xylosidic linkages. EC 3.2.1.8 catalyzes the endo-hydrolysis of 1,4-beta-D-xylosidic linkages; EC 3.2.1.32 catalyzes the endo-hydrolysis of 1,3-beta-D-xylosidic linkages; EC 3.2.1.37 catalyzes the exo-hydrolysis of 1,4-beta-D-linkages from the non-reducing termini of xylans; and EC 3.2.1.72 catalyzes the exo-hydrolysis of 1,3-beta-D-linkages from the non-reducing termini of xylans. Other xylosidases have been identified that catalyze the hydrolysis of alpha-xylosidic bonds.
Glycerol Kinase
An enzyme that catalyzes the formation of glycerol 3-phosphate from ATP and glycerol. Dihydroxyacetone and L-glyceraldehyde can also act as acceptors; UTP and, in the case of the yeast enzyme, ITP and GTP can act as donors. It provides a way for glycerol derived from fats or glycerides to enter the glycolytic pathway. EC 2.7.1.30.
Regulatory Sequences, Nucleic Acid
Acetoin
Styrene
Acetates
Benzyl Alcohols
Genetic Complementation Test
Mutagenesis, Insertional
Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene or extragenic sequence. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA insertions into or adjacent to a cellular proto-oncogene can interrupt GENETIC TRANSLATION of the coding sequences or interfere with recognition of regulatory elements and cause unregulated expression of the proto-oncogene resulting in tumor formation.
Cell-Free System
A fractionated cell extract that maintains a biological function. A subcellular fraction isolated by ultracentrifugation or other separation techniques must first be isolated so that a process can be studied free from all of the complex side reactions that occur in a cell. The cell-free system is therefore widely used in cell biology. (From Alberts et al., Molecular Biology of the Cell, 2d ed, p166)
Chromosome Mapping
Phosphotransferases
Bacillus megaterium
Fermentation
Lac Repressors
Transduction, Genetic
Fructose-Bisphosphatase
Biodegradation, Environmental
Sugar Alcohol Dehydrogenases
Mutagenesis
Pseudomonas aeruginosa
Restriction Mapping
Thiogalactosides
Membrane Transport Proteins
Alcohol Oxidoreductases
A subclass of enzymes which includes all dehydrogenases acting on primary and secondary alcohols as well as hemiacetals. They are further classified according to the acceptor which can be NAD+ or NADP+ (subclass 1.1.1), cytochrome (1.1.2), oxygen (1.1.3), quinone (1.1.5), or another acceptor (1.1.99).
Endo-1,4-beta Xylanases
DNA Footprinting
A method for determining the sequence specificity of DNA-binding proteins. DNA footprinting utilizes a DNA damaging agent (either a chemical reagent or a nuclease) which cleaves DNA at every base pair. DNA cleavage is inhibited where the ligand binds to DNA. (from Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
Trans-Activators
Hydro-Lyases
Proline
Sequence Homology, Amino Acid
Pectins
High molecular weight polysaccharides present in the cell walls of all plants. Pectins cement cell walls together. They are used as emulsifiers and stabilizers in the food industry. They have been tried for a variety of therapeutic uses including as antidiarrheals, where they are now generally considered ineffective, and in the treatment of hypercholesterolemia.
Transcriptional Activation
Agmatine
DNA Primers
Down-Regulation
Citric Acid Cycle
Electrophoretic Mobility Shift Assay
An electrophoretic technique for assaying the binding of one compound to another. Typically one compound is labeled to follow its mobility during electrophoresis. If the labeled compound is bound by the other compound, then the mobility of the labeled compound through the electrophoretic medium will be retarded.
Zinc Fingers
Motifs in DNA- and RNA-binding proteins whose amino acids are folded into a single structural unit around a zinc atom. In the classic zinc finger, one zinc atom is bound to two cysteines and two histidines. In between the cysteines and histidines are 12 residues which form a DNA binding fingertip. By variations in the composition of the sequences in the fingertip and the number and spacing of tandem repeats of the motif, zinc fingers can form a large number of different sequence specific binding sites.
Glutamate-Ammonia Ligase
Cellulase
Biological Transport
Pseudomonas
Ketoglutaric Acids
Isomerases
Alkanes
Nuclear Proteins
Species Specificity
The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.
Blotting, Northern
Glutamates
Signal Transduction
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
Streptococcus gordonii
Salmonella typhimurium
Pectobacterium chrysanthemi
Sorbitol
A polyhydric alcohol with about half the sweetness of sucrose. Sorbitol occurs naturally and is also produced synthetically from glucose. It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for some surgical procedures. It is also used in many manufacturing processes, as a pharmaceutical aid, and in several research applications.
Carrier Proteins
Sequence Analysis, DNA
Tryptophan
An essential amino acid that is necessary for normal growth in infants and for NITROGEN balance in adults. It is a precursor of INDOLE ALKALOIDS in plants. It is a precursor of SEROTONIN (hence its use as an antidepressant and sleep aid). It can be a precursor to NIACIN, albeit inefficiently, in mammals.
Acetic Acid
Protein Biosynthesis
Models, Genetic
Models, Biological
Hydrolases
Any member of the class of enzymes that catalyze the cleavage of the substrate and the addition of water to the resulting molecules, e.g., ESTERASES, glycosidases (GLYCOSIDE HYDROLASES), lipases, NUCLEOTIDASES, peptidases (PEPTIDE HYDROLASES), and phosphatases (PHOSPHORIC MONOESTER HYDROLASES). EC 3.
Sinorhizobium meliloti
Asparaginase
Phosphorylation
Glycosides
Any compound that contains a constituent sugar, in which the hydroxyl group attached to the first carbon is substituted by an alcoholic, phenolic, or other group. They are named specifically for the sugar contained, such as glucoside (glucose), pentoside (pentose), fructoside (fructose), etc. Upon hydrolysis, a sugar and nonsugar component (aglycone) are formed. (From Dorland, 28th ed; From Miall's Dictionary of Chemistry, 5th ed)
Consensus Sequence
A theoretical representative nucleotide or amino acid sequence in which each nucleotide or amino acid is the one which occurs most frequently at that site in the different sequences which occur in nature. The phrase also refers to an actual sequence which approximates the theoretical consensus. A known CONSERVED SEQUENCE set is represented by a consensus sequence. Commonly observed supersecondary protein structures (AMINO ACID MOTIFS) are often formed by conserved sequences.
Multigene Family
A set of genes descended by duplication and variation from some ancestral gene. Such genes may be clustered together on the same chromosome or dispersed on different chromosomes. Examples of multigene families include those that encode the hemoglobins, immunoglobulins, histocompatibility antigens, actins, tubulins, keratins, collagens, heat shock proteins, salivary glue proteins, chorion proteins, cuticle proteins, yolk proteins, and phaseolins, as well as histones, ribosomal RNA, and transfer RNA genes. The latter three are examples of reiterated genes, where hundreds of identical genes are present in a tandem array. (King & Stanfield, A Dictionary of Genetics, 4th ed)
Spores, Bacterial
Monosaccharide Transport Proteins
Transformation, Genetic
Streptococcus mutans
Gene Silencing
Phenotype
Epigenetic Repression
Mannitol
A diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place. It can be used to treat oliguria associated with kidney failure or other manifestations of inadequate renal function and has been used for determination of glomerular filtration rate. Mannitol is also commonly used as a research tool in cell biological studies, usually to control osmolarity.
Oxidoreductases
The class of all enzymes catalyzing oxidoreduction reactions. The substrate that is oxidized is regarded as a hydrogen donor. The systematic name is based on donor:acceptor oxidoreductase. The recommended name will be dehydrogenase, wherever this is possible; as an alternative, reductase can be used. Oxidase is only used in cases where O2 is the acceptor. (Enzyme Nomenclature, 1992, p9)
Chromosomes, Bacterial
Carboxylic Acids
Mutagenesis, Site-Directed
Glycolysis
A metabolic process that converts GLUCOSE into two molecules of PYRUVIC ACID through a series of enzymatic reactions. Energy generated by this process is conserved in two molecules of ATP. Glycolysis is the universal catabolic pathway for glucose, free glucose, or glucose derived from complex CARBOHYDRATES, such as GLYCOGEN and STARCH.
Gene Expression Profiling
Adenylate Cyclase
Extrachromosomal Inheritance
Integration Host Factors
Transcriptional analysis of differential carbohydrate utilization by Clostridium acetobutylicum. (1/31)
(+info)Catabolite repression of Aox in Pichia pastoris is dependent on hexose transporter PpHxt1 and pexophagy. (2/31)
(+info)Simultaneous consumption of pentose and hexose sugars: an optimal microbial phenotype for efficient fermentation of lignocellulosic biomass. (3/31)
(+info)Escherichia coli mhpR gene expression is regulated by catabolite repression mediated by the cAMP-CRP complex. (4/31)
(+info)Metabolomics of Mycobacterium tuberculosis reveals compartmentalized co-catabolism of carbon substrates. (5/31)
(+info)Computational prediction of the Crc regulon identifies genus-wide and species-specific targets of catabolite repression control in Pseudomonas bacteria. (6/31)
(+info)cAMP receptor protein (CRP) positively regulates the yihU-yshA operon in Salmonella enterica serovar Typhi. (7/31)
(+info)Multifactorial induction of an orphan PKS-NRPS gene cluster in Aspergillus terreus. (8/31)
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Catabolite repression
Carbon catabolite repression, or simply catabolite repression, is an important part of global control system of various ... Note that E. coli has a similar cAMP-independent catabolite repression mechanism that utilizes a protein called catabolite ... the synthesis of β-galactosidase is under repression due to the effect of catabolite repression caused by glucose. The ... is actually a misnomer since other carbon sources are known to induce catabolite repression.[citation needed] Catabolite ...
Diauxic growth
Stülke J, Hillen W. (1999). "Carbon catabolite repression in bacteria". Current Opinion in Microbiology. 2 (2): 195-201. doi: ... is required for the catabolite activator protein (CAP) to bind to DNA and activate the transcription of the lac operon, which ...
Lac operon
Two puzzles of catabolite repression relate to how cAMP levels are coupled to the presence of glucose, and secondly, why the ... Catabolite repression Griffiths, Anthony J.F.; Wessler, Susan R.; Carroll, Sean B.; Doebley, John (2015). An Introduction to ... Görke B, Stülke J (August 2008). "Carbon catabolite repression in bacteria: many ways to make the most out of nutrients". ... Binding of RNA polymerase to the promoter is aided by the cAMP-bound catabolite activator protein (CAP, also known as the cAMP ...
Catabolite activator protein
This phenomenon is known as catabolite repression. CAP plays an important role in catabolite repression, a well-known example ... p. 193 Catabolite+Activator+Protein at the US National Library of Medicine Medical Subject Headings (MeSH) v t e (Articles with ... Catabolite activator protein (CAP; also known as cAMP receptor protein, CRP) is a trans-acting transcriptional activator that ... Lawson CL, Swigon D, Murakami KS, Darst SA, Berman HM, Ebright RH (2004). "Catabolite activator protein: DNA binding and ...
Fed-batch culture
4. Catabolite repression[1] When a microorganism is provided with a rapidly metabolizable carbon-energy source such as glucose ... A powerful method of overcoming the catabolite repression in the enzyme biosynthesis is a fed-batch culture in which glucose ... This phenomenon is known as catabolite repression. Many enzymes, especially those involved in catabolic pathways, are subject ... Substrate limitation also allows the metabolic control, to avoid osmotic effects, catabolite repression and overflow metabolism ...
Streptomyces albaduncus
Harchand, R. K.; Singh, S (1994). "Catabolite repression of cellulase biosynthesis in Streptomyces albaduncus". Journal of ...
Ian A. Graham
Graham, I. A.; Denby, K. J.; Leaver, C. J. (1994). "Carbon Catabolite Repression Regulates Glyoxylate Cycle Gene Expression in ...
Thermotoga neapolitana
Vargas M; Noll KM (January 1996). "Catabolite repression in the hyperthermophilic bacterium Thermotoga neapolitana is ...
CrcZ
... is a small RNA found in Pseudomonas bacteria, which acts as a global regulator of carbon catabolite repression. In P. ... Sonnleitner E, Abdou L, Haas D (December 2009). "Small RNA as global regulator of carbon catabolite repression in Pseudomonas ... Sonnleitner E, Bläsi U (June 2014). "Regulation of Hfq by the RNA CrcZ in Pseudomonas aeruginosa carbon catabolite repression ... and catabolite repression is high. In the presence of poor sources of carbon, such as mannitol, CrcZ expression is high, ...
Super Optimal Broth
... with Catabolite repression (SOC) is SOB with added glucose. (Figures in parentheses are the masses required ...
Clostridium difficile toxin A
Environmental stresses such as antibiotics and catabolite repression can influence toxin expression. The tcdA and tcdB genes ...
Mal regulon
546 malT is regulated by catabolite repression via the catabolite activator protein. Genes under the control of malT include ...
Crc (protein)
The Catabolite repression control (Crc) protein participates in suppressing expression of several genes involved in utilization ... Zhang L, Chiang WC, Gao Q, Givskov M, Tolker-Nielsen T, Yang L, Zhang G (December 2012). "The catabolite repression control ... Sonnleitner E, Bläsi U (June 2014). "Regulation of Hfq by the RNA CrcZ in Pseudomonas aeruginosa carbon catabolite repression ... "Regulation of Hfq by the RNA CrcZ in Pseudomonas aeruginosa carbon catabolite repression". PLOS Genetics. 10 (6): e1004440. doi ...
LacUV5
Some of them, including UV5, has lost catabolite repression at the CAP site. Development into cloning vectors is known since ... Silverstone, AE; Arditti, RR; Magasanik, B (July 1970). "Catabolite-insensitive revertants of lac promoter mutants". ...
Agnes Ullmann
Later, she discovered another factor that boosts catabolite repression (catabolite modulator factor, or CMF). Ullmann ... In 1967 she showed that cAMP reverses catabolite repression in the bacterium E. coli. ...
Aspergillus versicolor
Xylanase is a secondary metabolite controlled through gene-specific induction and carbon catabolite repression. Many ...
MTOR
Peter GJ, Düring L, Ahmed A (March 2006). "Carbon catabolite repression regulates amino acid permeases in Saccharomyces ... "Sustained translational repression by eIF2α-P mediates prion neurodegeneration". Nature. 485 (7399): 507-11. Bibcode:2012Natur. ... "PML inhibits HIF-1alpha translation and neoangiogenesis through repression of mTOR". Nature. 442 (7104): 779-85. Bibcode: ...
Penicillium decumbens
"Transcription analysis of lignocellulolytic enzymes of Penicillium decumbens 114-2 and its catabolite-repression-resistant ...
Butanol fuel
Nakashima, Nobutaka; Tamura, Tomohiro (1 July 2012). "A new carbon catabolite repression mutation of Escherichia coli, mlc∗, ...
Sucrose phosphorylase
Global regulation of DNA molecules containing the gene for sucrose phosphorylase is performed by catabolite repression. First ...
Walter Dobrogosz
Lee JH, Dobrogosz WJ (May 1983). "Effects of aerobic and anaerobic shock on catabolite repression in cyclic AMP suppressor ... In particular, his research focused on the phenomenon of catabolite repression, a regulatory system involving interactions of ... cyclic AMP, the catabolite repressor protein (CRP) complex, and the lac operon and other inducible systems in bacteria. The ...
GalP (protein)
Galactose is an alternate carbon source to the preferable glucose . The cAMP/CRP catabolite repression regulator is most likely ... 5. El Qaidi, S., Allemand, J.O., and Plumbridge, J. (2009). Repression of galP, the galactose transporter in Escherichia coli, ... so both of these proteins are required for repression (11). cAMP is what modulates CRP at the promoter. The cAMP-CRP complex ... a protein from the nagC gene which is responsible for N-acetylglucosamine repression (5). This study suspects that NagC ...
CCR4-Not
Carbon Catabolite Repression-Negative On TATA-less, or CCR4-Not, is a multiprotein complex that functions in gene expression. ...
Morpheein
2004). "HPr kinase/phosphorylase, a Walker motif A-containing bifunctional sensor enzyme controlling catabolite repression in ...
SuhB
... which results in thn gene repression in catabolite repression conditions. EcpR1 sRNA RcsR1 small RNA Corbino KA, Barrick JE, ... catabolite repression conditions). This phenotype is due to the release of the negative effect of suhB on ThnR translation. Hfq ... a small non-coding RNA involved in catabolite repression of tetralin degradation genes in Sphingopyxis granuli strain TFA". ...
Karine A. Gibbs
She found that the catabolite repression control protein, which regulates carbon metabolism, is essential for biofilm formation ...
Spot 42 RNA
"The Base-Pairing RNA Spot 42 Participates in a Multioutput Feedforward Loop to Help Enact Catabolite Repression in Escherichia ... The direct responsiveness of Spot 42 levels to glucose and cAMP is due to repression of spf expression by a cAMP-CRP (cAMP- ...
P. N. Rangarajan
Vijay Kumar, N.; Rangarajan, P. N. (2011). "Catabolite repression of phosphoenolpyruvate carboxykinase by a zinc finger protein ... Rabies vaccine Foot-and-mouth disease Plasmodium falciparum Catabolite repression India portal Medicine portal Long link - ...
Quorum sensing
This explains why, when grown with glucose, E. coli will lose the ability to internalize AI-2 (because of catabolite repression ...
Changestat
... biology approach reveals that overflow metabolism of acetate in Escherichia coli is triggered by carbon catabolite repression ...
Sterigmatocystin
... carbon catabolite repression) but independent of CreA when glucose is used as sole carbon source. Instead, it was shown to be ...
No-SCAR (Scarless Cas9 Assisted Recombineering) Genome Editing
... super optimal broth with catabolite repression), colonies were patched onto selective plates using a toothpick and incubated at ...
Thermomyces lanuginosus
... because the invertase is insensitive to catabolite repression by glucose, and because the activity of the glucose uptake system ...
CCR
... a variation of Cardiopulmonary Resuscitation Carbon catabolite repression, part of the adaptive metabolic control system ...
Botryosphaeran
Catabolite repression, and the presence of β-glucan-hydrolyzing enzymes that attack botryosphaeran during the fermentation ...
Dcu family
... while it is repressed by nitrate and subject to CRP-mediated catabolite repression. DcuC family Zientz E, Six S, Unden G ( ...
Escherichia coli
Catabolite repression has also been observed in E. coli in the presence of other non-glucose sugars, such as arabinose and ... In E. coli, glucose catabolite repression is regulated by the phosphotransferase system, a multi-protein phosphorylation ... bacteria will often consume the sugars sequentially through a process known as catabolite repression. By repressing the ...
CRC
... catabolite repression control protein Criminal record check Cross Racing Championship Extreme 2005 (CRC 2005), a car-racing ...
CCR4
... is a cell-surface protein and should not be confused with the unrelated carbon catabolite repression-negative on TATA-less ...
SLC46A3
A proposed function of SLC46A3 of rising importance is the direct transport of maytansine-based catabolites from the lysosome ... Silencing mechanisms include mRNA cleavage and translation repression based on the level of complementarity between the miRNA ... Among the different types of antibody-drug conjugates (ADCs), maytansine-based noncleavable linker ADC catabolites, such as ... The clinical significance of SLC46A3 surrounds the protein's activity as a transporter of maytansine-based ADC catabolites. ...
Expression vector
... most commonly used lac or lac-derived promoters are based on the lacUV5 mutant which is insensitive to catabolite repression. ... "Catabolite-insensitive revertants of lac promoter mutants". Proceedings of the National Academy of Sciences USA. 66 (3): 773-9 ...
Is T7 expression subject to catabolite repression in NEB T7 Express or SHuffle strains? | NEB
FAQ: Is T7 expression subject to catabolite repression in NEB T7 Express or SHuffle strains?. The T7 RNA polymerase gene is ... Home FAQs Is T7 expression subject to catabolite repression in NEB T7 Express or SHuffle strains? ... Since expression is controlled by the wt lac operon, glucose addition will result in catabolite repression. Thus, basal protein ...
VIB1, a Link between Glucose Signaling and Carbon Catabolite Repression, Is Essential for Plant Cell Wall Degradation by...
Genes required for repression of cellulase gene expression when preferred carbon sources are present (carbon catabolite ... We show that disabling CRE1 repression and modulating the glucose response by deletion of col-26 restored growth of the Δvib-1 ... Cellulase production is subject to induction by the presence of plant biomass components and to repression by the availability ... but the mechanisms involved in crosstalk between repression versus induction of cellulase gene expression is poorly understood ...
IMSEAR at SEARO: Recovery from ultraviolet light-induced catabolite repression of L-arabinose isomerase.
Computational Biology
Transcription of sialic acid catabolism genes in Corynebacterium glutamicum is subject to catabolite repression and control by...
Carbon catabolite repression in bacteria: many ways to make the most out of nutrients.. Gorke B, Stulke J., Nat. Rev. Microbiol ... The mechanisms of carbon catabolite repression in bacteria.. Deutscher J., Curr. Opin. Microbiol. 11(2), 2008 PMID: 18359269 ... Carbon catabolite repression by seryl phosphorylated HPr is essential to Streptococcus pneumoniae in carbohydrate-rich ... The alcohol dehydrogenase gene adhA in Corynebacterium glutamicum is subject to carbon catabolite repression.. Arndt A, ...
Search Ageing-Associated Genes in Model Organisms
metabolic process - Ontology Report - Rat Genome Database
Bloom FR - Search Results - PubMed
Clinical and Molecular Epidemiology of Staphylococcal Toxic Shock Syndrome in the United Kingdom - Volume 24, Number 2-February...
Flux limitations in the ortho pathway of benzoate degradation of Alcaligenes eutrophus: metabolite overflow and induction of...
MacGregor C.H., Wolff J. A., Arora S. K., Hylemon P. B., Phibbs P. V. 1992; Catabolite repression control in Pseudomonas ... evidence of carbon catabolite repression control. J Bacteriol 176:2354-2361 ... Mandelstam J., Jacoby G. A. 1965; Induction and multi-sensitive end-product repression in the enzymatic pathway de-grading ...
DAL1 (YIR027C) Result Summary | BioGRID
Dataset for ''Screen printed carbon CsPbBr3 perovskite solar cells with high open-circuit photovoltage'' - Projects - the...
Site - malE
Team:Caltech/Project/Lactose intolerance - 2008.igem.org
Ctrl-X, Ctrl-V For DNA | Hackaday
Molecular Structure Characterization Unit | RIKEN
George A. O'Toole , NC DOCKS (North Carolina Digital Online Collection of Knowledge and Scholarship)
Thomas Sauter
Publications of the Institute | Max Planck Institute for Dynamics of Complex Technical Systems
Comparative study for oxygenases produced by Aspergillus niger, ATCC 9642, in solid-state and submerged fermentation
Apparently there was catabolite repression which was more severe for culture medium g which contained the double of glucose ... Several authors have proposed that SSF system minimizes the catabolite repression (Ramesh and Lonsane, 1991; Aguilar, et al., ... It will be interesting to look for molecules that act as signal molecules in catabolite repression. Besides to study glucose ... del Castillo, T. and Ramos, J. L. (2007). Simultaneous catabolite repression between glucose and toluene metabolism in ...
An ensemble of mathematical models showing diauxic growth behaviour - Inria - Institut national de recherche en sciences et...
Vicky Shingler
Multiple Hfq-Crc target sites are required to impose catabolite repression on (methyl)phenol metabolism in Pseudomonas putida ... Multiple Hfq-Crc target sites are required to impose catabolite repression on (methyl)phenol metabolism in Pseudomonas putida ... The Crc and Hfq proteins of Pseudomonas putida cooperate in catabolite repression and formation of ribonucleic acid complexes ... AccR is a master regulator involved in carbon catabolite repression of the anaerobic catabolism of aromatic compounds in ...
Microbial solvent formation revisited by comparative genome analysis | Biotechnology for Biofuels and Bioproducts | Full Text
Catabolite repression of α amylase gene expression in Bacillus subtilis involves a trans-acting gene product homologous to the ... CcpA is essential for catabolite repression; and Rex controls multiple genes affecting the redox status of the cells [27-30]. ... Ren C, Gu Y, Wu Y, Zhang W, Yang C, Yang S, Jiang W. Pleiotropic functions of catabolite control protein CcpA in butanol- ...
View source for Sinorhizobium meliloti - microbewiki
Genetics - Theses
A genome-wide analysis of carbon catabolite repression in Schizosaccharomyces pombe. Vassiliadis, Dane Aaron McKay (. 2018. ) ... at the transcriptional level to control the function of a conserved regulatory mechanism known as carbon catabolite repression ... and so there is limited knowledge of the range of genes that are subject to transcriptional repression, or of the functional ... is required for maximal transcriptional repression. Also implicated in this process is the transcriptional activator, Rst2, ...
Search | Preprints
Most microorganisms have evolved the ability to utilize it preferably due to carbon catabolite repression regulatory mechanism ... A brief insight on carbon catabolite repression and phosphostransferase system were made. It also highlighted the biogas ... BET bromodomain blockade using small-molecule inhibitors gives rise to selective repression of the transcriptional network ...
Papers | RITE Molecular Microbiology and Biotechnology group
14Inui M, Vertès AA and Yukawa H. Reverse catabolite repression and the regulation of CO2 fixation Rhodobacter and related ... exerts different degrees of repression depending on the location of its binding sites within the three target promoter regions ... Inui M and Yukawa H Translation efficiency of antiterminator proteins is a determinant for the difference in glucose repression ...
Expression of a novel gene, gluP, is essential for normal Bacillus subtilis cell division and contributes to glucose export |...
Paulsen IT, Chauvaux S, Choi P, Saier MH: Characterization of glucose specific catabolite repression-resistant mutants of ... Putative contribution of glucose kinase from Bacillus subtilis to carbon catabolite repression (CCR): a link between enzymatic ... and the HPr kinase leading to carbon catabolite repression [9]. The glucose-transporting PTS, which is bacterial specific, ... transcription repression complex, and (d) protein import complex [24]. Based on this functional deduction, the C-terminus ...
Find Research outputs
- Ulster University
MH DELETED MN ADDED MN
Catabolite Repression G6.590.235 G3.194 G5.308.48 G6.173 Catalysis G2.149.170 G2.130 G2.149.767.500 G2.842.750.500 Catalytic ... Enzyme Repression G5.355.315.320.300 G5.308.320.300 Eosine I Bluish D3.494.953.275.300 D3.633.300.953.275.300 Eosine Yellowish ... YS) D3.494.953.275.325 D3.633.300.953.275.325 Epigenesis, Genetic G5.355.315.203 G5.308.203 Epigenetic Repression G5.355. ...
Subject to catabolite repression1
- Is T7 expression subject to catabolite repression in NEB T7 Express or SHuffle strains? (neb.com)
Carbon5
- Inducibility of the TOL catabolic pathways in Pseudomonas putida (pWWO) growing on succinate in continuous culture : evidence of carbon catabolite repression control. (microbiologyresearch.org)
- E. coli are unable to uptake lactose in the presence of glucose, a phenomenon known as carbon catabolite repression. (igem.org)
- Background Carbon catabolite repression (CCR) controls the order in which different carbon sources are metabolised. (inria.fr)
- Specifically, sugar mixtures are often incompletely metabolized due to carbon catabolite repression while composition variability further complicates the optimization of co-utilization rates. (elsevier.com)
- We show that alpha-glucan degrading activity dissipates when Lactobacillus crispatus is grown on glucose, maltose and maltotriose, in agreement with carbon catabolite repression elements flanking the pulA gene. (bvsalud.org)
Escherichia3
Maltose1
- Regulatory, loss of catabolite repression: growth on maltose + a-methylgucoside. (yale.edu)
Glucose2
Genes2
- Process by which micro-organisms adapt quickly to a preferred rapidly-metabolizable intermediate through the inhibition or repression of genes related to CATABOLISM of less preferred source(s). (bvsalud.org)
- This repression was not dependent on either the fnr or resDE gene products, which have been shown to regulate expression of other B. subtilis genes in response to anaerobic conditions. (elsevier.com)
Control1
- Additionally, catabolite control proteins CcpA and CcpB were not responsible for the repression. (elsevier.com)
Gene1
- A dyad symmetry element located between positions -73 and -59 relative to the transcription start site of the aconitase gene (citB) promoter was previously shown to be a target of catabolite repression and the binding site for a putative negative regulator during aerobic growth. (elsevier.com)
Growth1
- The deletion of the upstream arm of the dyad symmetry region abolished the citB repression observed during anaerobic growth. (elsevier.com)
Nitrogen5
- This nitrogen-response system, often referred to as nitrogen catabolite repression, is found in many fungi and bacteria. (nih.gov)
- Nitrogen metabolite repression in Aspergillus nidulans . (zju.edu.cn)
- Link to all annotated objects annotated to nitrogen catabolite regulation of transcription. (cyverse.org)
- Link to all direct and indirect annotations to nitrogen catabolite regulation of transcription. (cyverse.org)
- however, repression could be relieved completely when 4-aminobutyrate (GABA) served as the sole nitrogen source. (unipr.it)
Pseudomonas2
- In this study the role of Crc in catabolite repression control has been studied in Pseudomonas putida. (uncg.edu)
- Effect of vfr mutation on global gene expression and catabolite repression control of Pseudomonas aeruginosa. (jefferson.edu)
Protein6
- We identified a putative catabolite-responsive element (cre) in the promoter regions of all known tst genes, indicating that tst transcription may be regulated by the catabolite control protein CcpA. (nih.gov)
- chaperone Hfq, the catabolite repression control protein Crc and the regulatory RNA CrcZ (1,7). (biologyexperimentideas.net)
- Catabolite repression in Escherichia coli mutants lacking cyclic AMP receptor protein. (nih.gov)
- Cyclic AMP receptor protein was originally identified as a catabolite gene activator protein. (jefferson.edu)
- Galinier A, Kravanja M, Engelmann R, Hengstenberg W, Kilhoffer MC, Deutscher J, Haiech J (1998) New protein kinase and protein phosphatase families mediate signal transduction in bacterial catabolite repression. (genome.jp)
- La répression catabolique est étudiée sous différents aspects sur la bactérie phytopathogène modèle: du contrôle de l'expression de genes d'utilisation de la plante implicant le régulateur CRP (Catabolite Repression Protein) à des approches globales des réseaux de régulation chez les bactéries phytopathogènes. (insa-lyon.fr)
Operons1
- They have been phenotypically characterized and their ability to enhance the expression of catabolite-repressible operons has been tested. (nih.gov)
Proteins1
- Theseobservations suggest that microorganisms use similar conserved domains tosense similar environmental signals and transmit this information viadifferent signal transduction pathways to different regulatory circuits:transcriptional regulation (histidine kinases), chemotaxis(methyl-accepting proteins), catabolite repression (adenylate cyclases),and modulation of enzyme activity (diguanylate cyclases andphosphodiesterases). (embl.de)
Mutant1
- This is the first report of a successful catabolite repression insensitivity of cellulase production by a mutant of B. pumilus, and is particularly significant when compared to Trichoderma reesei a well-known cellulase producer, which is under control of end-product inhibition. (semanticscholar.org)
Intracellular1
- Catabolite repression in Campylobacter jejuni correlates with intracellular succinate levels. (bio-protocol.org)
Nucleus1
- cAMP, or cyclic adenosine monophosphate -- A form of AMP, generated from ATP by adenylyl cyclase in response to the stimulation of many types of cell-surface receptors, used frequently as a second messenger in eukaryotics (cells containing one nucleus) and in catabolite repression in prokaryotes (cells containing no nucleus). (nih.gov)
Feedback1
- Om du har frågor, behöver hjälp, hittar en bugg eller vill ge feedback kan du göra det här nedan. (chalmers.se)
Broad1
- FOG-1-dependent repression can be accompanied by broad histone deacetylation (Grass et al. (booksc.org)