Cat-Scratch Disease
Bartonella henselae
Bartonella
Angiomatosis, Bacillary
Bartonella quintana
Bartonella Infections
Cats
Rickettsiaceae
Cat Diseases
Trench Fever
Fluorescent Antibody Technique, Indirect
Immunocompetence
Polymerase Chain Reaction
Lymph Nodes
RNA, Ribosomal, 16S
Immunoglobulin M
Sensitivity and Specificity
Cat-scratch disease with paravertebral mass and osteomyelitis. (1/178)
The case of a 9-year-old girl with cat-scratch disease (CSD) complicated by development of a paravertebral mass and osteomyelitis is presented. Following multiple scratches and inguinal lymphadenopathy, she developed back pain, and imaging demonstrated a paravertebral mass with evidence of osteomyelitis involving vertebra T9. The diagnosis was made on the basis of detection of Bartonella henselae by use of molecular techniques on an aspirate from the vertebral column and supportive serology for infection with B. henselae. Eleven other cases of this unusual manifestation associated with CSD have been reported in the literature and are reviewed. The patient was treated with gentamicin, followed by rifampicin and trimethoprim-sulfamethoxazole, orally and made a favorable recovery over 7 months. This is comparable with other case reports, regardless of the choice of antibiotic therapy. CSD in immunocompetent hosts is not always self-limiting, and tissues beyond the lymph nodes can be involved. (+info)Detection of Bartonella henselae DNA by two different PCR assays and determination of the genotypes of strains involved in histologically defined cat scratch disease. (2/178)
Cat scratch disease (CSD) is a common cause of subacute regional lymphadenopathy, not only in children but also in adults. Serological and molecular studies demonstrated that Bartonella henselae is the etiologic agent in most cases of CSD. Amplification of B. henselae DNA in affected tissue and detection of antibodies to B. henselae are the two mainstays in the laboratory diagnosis of CSD. We designed a retrospective study and investigated formalin-fixed, paraffin-embedded lymph nodes from 60 patients (25 female, 35 male) with histologically suspected CSD by PCR amplification. The sensitivities of two different PCR assays were compared. The first primer pair amplified a 296-bp fragment of the 16S rRNA gene in 36 of the 60 samples, corresponding to a sensitivity of 60%. The second primer pair amplified a 414-bp fragment of the htrA gene in 26 of the 60 lymph nodes, corresponding to a sensitivity of 43.3%. Bartonella DNA could be detected in a total of 39 (65%) of the 60 lymph nodes investigated. However, histopathologic findings are typical but not specific for CSD and cannot be considered as a "gold standard" for diagnosis of CSD. The sensitivity of the PCR assays increased from 65 to 87% if two criteria (histology and serology) were used in combination for diagnosis of CSD. Two genotypes (I and II) of B. henselae are described as being involved in CSD. Genotype I was found in 23 (59%) and genotype II was found in 9 (23%) of the 39 PCR-positive lymph nodes. Seven (18%) lymph nodes were negative in both type-specific PCR assays. Thirty (50%) of our 60 patients were younger than 20 years old (15 were younger than 10 years), 20 (33%) were between 21 and 40 years old, and 10 (17%) patients were between 41 and 84 years old. Our data suggest that detection of Bartonella DNA in patients' samples might confirm the histologically suspected diagnosis of CSD. (+info)Clinical and pathologic evaluation of chronic Bartonella henselae or Bartonella clarridgeiae infection in cats. (3/178)
Human Bartonella infections result in diverse medical presentations, whereas many cats appear to tolerate chronic bacteremia without obvious clinical abnormalities. Eighteen specific-pathogen-free cats were inoculated with Bartonella henselae- and/or Bartonella clarridgeiae-infected cat blood and monitored for 454 days. Relapsing bacteremia did not correlate with changes in protein profiles or differences in antigenic protein recognition. Intradermal skin testing did not induce a delayed type hypersensitivity reaction to cat scratch disease skin test antigen. Thirteen cats were euthanatized at the end of the study. Despite persistent infection, clinical signs were minimal and gross necropsy results were unremarkable. Histopathology revealed peripheral lymph node hyperplasia (in all of the 13 cats), splenic follicular hyperplasia (in 9 cats), lymphocytic cholangitis/pericholangitis (in 9 cats), lymphocytic hepatitis (in 6 cats), lymphoplasmacytic myocarditis (in 8 cats), and interstitial lymphocytic nephritis (in 4 cats). Structures suggestive of Bartonella were visualized in some Warthin-Starry stained sections, and Bartonella DNA was amplified from the lymph node (from 6 of the 13 cats), liver (from 11 cats) heart (from 8 cats), kidney (from 9 cats), lung (from 2 cats), and brain (from 9 cats). This study indicates that B. henselae or B. clarridgeiae can induce chronic infection following blood transfusion in specific-pathogen-free cats and that Bartonella DNA can be detected in blood, brain, lymph node, myocardium, liver, and kidney tissues of both blood culture-positive cats and blood culture-negative cats. Detection of histologic changes in these cats supports a potential etiologic role for Bartonella species in several idiopathic disease processes in cats. (+info)Culture of Bartonella quintana and Bartonella henselae from human samples: a 5-year experience (1993 to 1998). (4/178)
Bartonella quintana and Bartonella henselae are fastidious gram-negative bacteria responsible for bacillary angiomatosis, trench fever, cat scratch disease, and endocarditis. During a 5-year period, we received 2,043 samples for culture of Bartonella sp. We found Bartonella sp. to be the etiologic agent in 38 cases of endocarditis, 78 cases of cat scratch disease, 16 cases of bacteremia in homeless people, and 7 cases of bacillary angiomatosis. We correlated the results of positive cultures with the clinical form of the disease, type of sample, culture procedure, PCR-based genomic detection, and antibody determination. Seventy-two isolates of B. quintana and nine isolates of B. henselae from 43 patients were obtained. Sixty-three of the B. quintana isolates and two of the B. henselae isolates, obtained from patients with no prior antibiotic therapy, were stably subcultured. The sensitivity of culture was low when compared with that of PCR-based detection methods in valves of patients with endocarditis (44 and 81%, respectively), skin biopsy samples of patients with bacillary angiomatosis (43 and 100%, respectively), and lymph nodes of cat scratch disease (13 and 30%, respectively). Serological diagnosis was also more sensitive in cases of endocarditis (97%) and cat scratch disease (90%). Among endocarditis patients, the sensitivity of the shell vial culture assay was 28% when inoculated with blood samples and 44% when inoculated with valvular biopsy samples, and the sensitivity of both was significantly higher than that of culture on agar (5% for blood [P = 0.045] and 4% for valve biopsy samples [P < 0.0005]). The most efficient culture procedure was the subculture of blood culture broth into shell vials (sensitivity, 71%). For patients with endocarditis, previous antibiotic therapy significantly affected results of blood culture; no patient who had been administered antibiotics yielded a positive blood culture, whereas 80% of patients with no previous antibiotic therapy yielded positive blood cultures (P = 0.0006). Previous antibiotic therapy did not, however, prevent isolation of Bartonella sp. from cardiac valves but did prevent the establishment of strains, as none of the 15 isolates from treated patients could be successfully subcultured. For the diagnosis of B. quintana bacteremia in homeless people, the efficiency of systematic subculture of blood culture broth onto agar was higher than that of direct blood plating (respective sensitivities, 98 and 10% [P < 10(-7)]). Nevertheless, both procedures are complementary, since when used together their sensitivity reached 100%. All homeless people with positive blood cultures had negative serology. The isolation rate of B. henselae from PCR-positive lymph nodes, in patients with cat scratch disease, was significantly lower than that from valves of endocarditis patients and skin biopsy samples from bacillary angiomatosis patients (13 and 33%, respectively [P = 0.084]). In cases of bacillary angiomatosis for which an agent was identified to species level, the isolation rate of B. henselae was lower than the isolation rate of B. quintana (28 and 64%, respectively [P = 0.003]). If culture is to be considered an efficient tool for the diagnosis of several Bartonella-related diseases, methodologies need to be improved, notably for the recovery of B. henselae from lymph nodes of patients with cat scratch disease. (+info)Acute clinical disease in cats following infection with a pathogenic strain of Bartonella henselae (LSU16). (5/178)
Bartonella henselae is the causative agent of human cat scratch disease as well as several serious sequelae of infections, including bacillary angiomatosis and bacillary peliosis. Conflicting reports describe the pathogenesis of B. henselae in the cat. In this study, we characterized a strain of B. henselae termed LSU16. This strain was isolated on rabbit blood agar from a naturally infected 10-month-old female cat during a recurrent episode of bacteremia. The bacterial species was confirmed by PCR-restriction fragment length polymorphism analysis. Nine cats were infected intradermally with 5 x 10(7) CFU of LSU16, and clinical signs, antibody responses, and bacteremia were monitored. All nine cats developed raised, erythematous areas at the site of inoculation within 72 h postinoculation; the swelling peaked at 14 days postinfection and was not palpable by 28 days postinfection. Fever developed in all nine cats between 6 and 16 days postinfection and lasted for 1 to 8 days. Between 6 and 16 days postinfection, all nine cats experienced lethargy which persisted 5 to 18 days. Seven of nine cats were bacteremic by day 7, and all nine cats had become bacteremic by 14 days postinfection. Bacteremia peaked at 14 to 28 days postinfection in all cats. In six of the nine infected cats, bacterial numbers reached nondetectable levels during the 7th week postinfection; however, a single animal maintained bacteremia to 18 weeks postinfection. All nine cats developed strong antibody responses to B. henselae, as determined by Western blot analysis and enzyme-linked immunosorbent assay. Subsequently, three naive cats were injected intradermally with blood from cats infected with LSU16 from a pure culture, and five naive cats were injected with feces from fleas which had been feeding on cats infected with a pure culture of LSU16. These cats developed signs similar to those described in the previous experiment and were euthanized at 5 weeks postinfection. We conclude that B. henselae LSU16 is a virulent strain of B. henselae in cats and propose that the virulence of B. henselae in cats is strain dependent. (+info)Presumed ocular bartonellosis. (6/178)
BACKGROUND: The spectrum of diseases caused by Bartonella henselae continues to expand and ocular involvement during this infection is being diagnosed with increasing frequency. METHODS: The clinical features and visual prognosis for 13 patients with intraocular inflammatory disease and laboratory evidence of bartonellosis were investigated. There were nine patients with neuroretinitis and four with panuveitis with positive antibody titres against B henselae determined by an enzyme immunoassay (IgG exceeding 1:900 and/or IgM exceeding 1:250). RESULTS: Positive IgG levels were found for eight patients and positive IgM levels for five. Despite animal exposure of 10 patients, only two (IgG positive) cases had systemic symptoms consistent with the diagnosis of cat scratch disease. Pathological fluorescein leakage of the optic disc was observed in all affected eyes. At 6 months' follow up, 3/18 (17%) affected eyes had a visual acuity of less than 20/100, owing to optic disc atrophy and cystoid macular oedema. 12 patients (17 eyes) were treated with antibiotics; visual acuity improved two or more Snellen lines for 9/17 (53%) eyes. CONCLUSIONS: The possibility of B henselae infection should be considered in patients with neuroretinitis and panuveitis (especially in cases with associated optic nerve involvement) even in the absence of systemic symptoms typical for cat scratch disease. (+info)Identification of Bartonella-specific immunodominant antigens recognized by the feline humoral immune system. (7/178)
The seroreactivities of both naturally and experimentally infected cats to Bartonella henselae was examined. Serum samples collected weekly from nine cats experimentally infected with B. henselae LSU16 were tested by enzyme-linked immunosorbent assay (ELISA) and Western blot analysis. The magnitude and isotype of the antibody response were investigated by ELISA. Western blot analysis allowed the identification of at least 24 Bartonella-specific antigens recognized by the cats during infection. Antibody titers to specific antigens, as determined by Western blot analysis, ranged from 10 to 640 and varied among the different antibody-antigen interactions. Absorption of sera from an experimentally infected cat, using whole cells and cell lysates of various Bartonella species and other bacteria that commonly colonize cats, supported the identification of those Bartonella-specific antigens recognized by the experimentally infected cats. Furthermore, a number of possible species- and type-specific antigens were identified. Finally, sera obtained from cats at local animal shelters were screened for the presence of antibodies directed against the Bartonella-specific bands identified in the experimentally infected cats. A number of Bartonella-specific antigens have been identified to which strong antibody responses are generated in both experimentally and naturally infected cats, some of which may be useful in diagnosing species- and/or type-specific infections. In addition, the results from these experiments will lead to the development of monoclonal antibodies targeted against those genus-, species-, and type-specific antigens. (+info)Characterization of Bartonella henselae-specific immunity in BALB/c mice. (8/178)
BALB/c mice were inoculated with Bartonella henselae by both systemic and mucosal routes. Culture analysis of tissues from mice infected intraperitoneally with a high dose of B. henselae yielded positive results 24 hr after infection. However, culture analysis of blood taken between 6 hr and 7 days after infection from groups receiving live B. henselae were negative. Following intraperitoneal infection, B. henselae was detected by polymerase chain reaction in liver and mesenteric lymph nodes by 6 hr and up to 7 days after infection in liver, kidney and spleen tissue. Enzyme-linked immunosorbent assay (ELISA) of serum samples collected as early as 13 days after infection indicated humoral immune responses to B. henselae. Specific humoral responses remained through week 6. Analysis of faecal samples revealed induction of B. henselae-specific immunoglobulin A by day 28 after infection. In addition, B. henselae-specific cellular responses were indicated by a positive delayed-type hypersensitivity and a T helper 1 (Th1) (CD4+ T cell)-type cytokine response following in vitro stimulation of splenocytes. The significance and implications of these data in relation to B. henselae infections are discussed. (+info)In more detail, the definition of 'Cat-Scratch Disease' in the medical field can be broken down into the following components:
1. Cat scratch or bite: The disease is transmitted to humans through the scratch or bite of an infected cat.
2. Bartonella henselae: The bacteria that causes the disease is Bartonella henselae.
3. Infected cats: The disease is typically found in domestic and wild cats, as well as in their fleas and lice.
4. Variety of symptoms: CDS can cause a range of symptoms including fever, headache, swollen lymph nodes, and skin lesions.
5. Diagnosis based on clinical presentation and laboratory tests: The diagnosis is based on a combination of the patient's symptoms, laboratory tests such as blood cultures and polymerase chain reaction (PCR), and serology.
6. Supportive treatment: Treatment for CDS is primarily supportive, with antibiotics reserved for severe cases or those with complications.
7. More common in children: Children are more susceptible to CDS than adults, as they are more likely to come into contact with infected cats and have a weaker immune system.
The symptoms of angiomatosis, bacillary can vary depending on the location and size of the angiomas, but they may include:
* Red or purple discoloration of the skin
* Swelling or lumps under the skin
* Pain or tenderness in the affected area
* Warmth or redness around the angioma
Angiomatosis, bacillary is diagnosed through a combination of physical examination, medical history, and laboratory tests (such as blood tests or biopsies). Treatment typically involves antibiotics to eradicate the bacterial infection. In some cases, surgical removal of the angioma may be necessary.
Prevention of angiomatosis, bacillary is aimed at avoiding contact with cat scratches or bites, and good hygiene practices (such as washing hands frequently) can help reduce the risk of infection. Vaccination against Bartonella henselae is not currently available for humans, but it is recommended for cats to prevent the spread of the bacteria.
The prognosis for angiomatosis, bacillary is generally good if treated promptly and effectively. However, in rare cases, the condition can progress to more severe forms, such as cat scratch disease or bartonellosis, which can have serious complications if left untreated.
1. Feline Leukemia Virus (FeLV): This is a highly contagious virus that weakens the immune system, making cats more susceptible to other infections and cancer.
2. Feline Immunodeficiency Virus (FIV): Similar to HIV in humans, this virus attacks the immune system and can lead to a range of secondary infections and diseases.
3. Feline Infectious Peritonitis (FIP): A viral disease that causes fluid accumulation in the abdomen and chest, leading to difficulty breathing and abdominal pain.
4. Feline Lower Urinary Tract Disease (FLUTD): A group of conditions that affect the bladder and urethra, including urinary tract infections and kidney stones.
5. Feline Diabetes: Cats can develop diabetes, which can lead to a range of complications if left untreated, including urinary tract infections, kidney disease, and blindness.
6. Feline Hyperthyroidism: An overactive thyroid gland that can cause weight loss, anxiety, and heart problems if left untreated.
7. Feline Cancer: Cats can develop various types of cancer, including lymphoma, leukemia, and skin cancer.
8. Dental disease: Cats are prone to dental problems, such as tartar buildup, gum disease, and tooth resorption.
9. Obesity: A common problem in cats, obesity can lead to a range of health issues, including diabetes, arthritis, and heart disease.
10. Behavioral disorders: Cats can develop behavioral disorders such as anxiety, stress, and aggression, which can impact their quality of life and relationships with humans.
It's important to note that many of these diseases can be prevented or managed with proper care, including regular veterinary check-ups, vaccinations, parasite control, a balanced diet, exercise, and mental stimulation. Additionally, early detection and treatment can significantly improve the outcome for cats with health issues.
What are some ways that modern medicine has improved upon the treatment of trench fever from World War I?
Modern medicine has made significant improvements in the treatment of trench fever since World War I. Here are some of the key advancements:
1. Antibiotics: During World War I, sulfonamides were used to treat trench fever, but these drugs were not very effective and often caused allergic reactions. Today, we have a range of more effective antibiotics, such as doxycycline and ciprofloxacin, which can effectively treat trench fever.
2. Supportive care: In World War I, supportive care was limited, and patients often had to endure severe symptoms with little relief. Today, supportive care has improved significantly, including the use of pain management techniques, hydration, and nutritional support to help manage symptoms and speed up recovery.
3. Diagnostic advancements: In World War I, trench fever was often misdiagnosed or undiagnosed, leading to inadequate treatment. Today, we have more sophisticated diagnostic tools, such as polymerase chain reaction (PCR) tests, which can quickly and accurately diagnose trench fever.
4. Better understanding of the disease: We now know more about the bacteria that cause trench fever and how it spreads, which has led to improved prevention and control measures. This includes the use of insecticides to kill body lice and the development of vaccines to protect against Bartonella infections.
5. Improved sanitation and hygiene: Good sanitation and hygiene practices are critical in controlling the spread of trench fever. In World War I, these practices were often lacking, leading to the spread of disease. Today, we have a much greater emphasis on proper handwashing, clean water, and waste disposal, which helps reduce the risk of infection.
In conclusion, while trench fever is still a serious illness today, advances in medicine and public health have significantly improved our ability to prevent, diagnose, and treat it. This has saved countless lives and reduced the impact of this disease on military personnel and civilian populations alike.
1. Lymphedema: This is a condition in which the lymph vessels are unable to properly drain fluid from the body, leading to swelling in the affected limb.
2. Lymphangitis: This is an inflammation of the lymph vessels that can cause pain, redness, and swelling.
3. Lymphadenitis: This is an infection of the lymph nodes that can cause swelling, pain, and difficulty breathing.
4. Primary lymphedema: This is a rare genetic condition in which the lymph vessels are missing or do not develop properly.
5. Secondary lymphedema: This is a condition that develops as a result of another condition or injury, such as surgery, radiation therapy, or infection.
6. Lymphatic malformations: These are abnormalities in the development of the lymph vessels and nodes that can cause swelling, pain, and difficulty breathing.
7. Lymphocystis: This is a rare condition in which small cysts form in the lymph vessels and nodes.
8. Lymphangioleiomyomatosis (LAM): This is a rare condition that causes cysts to form in the lungs and can also affect the lymph vessels and nodes.
9. Lipedema: This is a condition in which there is an abnormal accumulation of fat in the legs, thighs, and buttocks, which can cause swelling and pain.
10. Pemphigus: This is a group of rare autoimmune disorders that affect the skin and mucous membranes, leading to blistering and scarring.
Treatment for lymphatic diseases depends on the specific condition and may include compression garments, exercises, and manual lymph drainage therapy. In some cases, medications such as antibiotics or anti-inflammatory drugs may be prescribed to help manage symptoms. Surgery may also be necessary in some cases to remove blockages or repair damaged vessels.
It is important to seek medical attention if you experience any persistent swelling or pain, as these can be signs of a lymphatic disease. Early diagnosis and treatment can help to manage symptoms and improve quality of life.
Here are some examples of splenic diseases:
1. Enlarged Spleen (Splenomegaly): This can be caused by various conditions such as viral infections, malaria, and certain autoimmune disorders. An enlarged spleen can cause abdominal pain, fatigue, and difficulty breathing.
2. Sickle Cell Disease: This is a genetic disorder that affects the production of hemoglobin, leading to anemia and the formation of sickle-shaped red blood cells. The spleen becomes enlarged as it tries to filter out these abnormal cells.
3. Thalassemia: This is another genetic disorder that affects the production of hemoglobin, leading to anemia and the formation of abnormal red blood cells. The spleen can become enlarged in people with thalassemia.
4. Splenic Infarction: This occurs when there is a blockage of blood flow to the spleen, causing tissue death. It can be caused by various conditions such as blood clots, injury, or infection.
5. Splenic Cysts: These are fluid-filled sacs that develop within the spleen. They can be benign or malignant and can cause abdominal pain, bleeding, and other symptoms.
6. Splenic Tumors: These are abnormal growths of tissue in the spleen. They can be benign or malignant and can cause a variety of symptoms depending on their size and location.
7. Splenic Abscess: This is a collection of pus within the spleen, usually caused by an infection. It can cause fever, chills, and abdominal pain.
8. Splenectomy: This is the surgical removal of the spleen, often necessary for conditions such as enlarged spleens or cancerous tumors.
9. Trauma: The spleen can be injured by trauma to the abdomen, such as a car accident or fall. This can cause internal bleeding and other complications.
10. Infection: The spleen can become infected by bacteria, viruses, or other pathogens, leading to symptoms such as fever, chills, and abdominal pain.
It is important to note that some of these conditions can be serious and even life-threatening, so it is important to seek medical attention if you experience any symptoms that may be related to the spleen.
Cat-scratch disease
Cat bite
Bartonellosis
Lymphadenopathy
Onychectomy
Bartonella henselae
Afipia felis
Pierre Mollaret
Afipia clevelandensis
Bartonella
Afipia broomeae
Carrion's disease
Cat play and toys
Rats in New York City
Bartonella clarridgeiae
Interferon
Cat
Sporotrichosis
Granuloma
Warthin-Starry stain
Nitrobacteraceae
Parinaud's oculoglandular syndrome
Human interaction with cats
Bartonella apis
Zoonosis
Progressive transformation of germinal centres
William A. Petri
Clarithromycin
Cardiolipin
Dieterle stain
2022 monkeypox outbreak
List of diseases (C)
Orthopoxvirus
Trimeric autotransporter adhesin
Orf (disease)
Stop Online Piracy Act
History of the nude in art
Cat behavior
Richie Farmer
The Bridge on the River Kwai
List of kākāpō
The Persian
Tom Dula
List of Ig Nobel Prize winners
Mycoplasma haemofelis
Olfactory system
Waded Cruzado
Cat communication
Center for Public Integrity
List of skin conditions
Lemur
Superman (1978 film)
Malassezia pachydermatis
Sunglasses
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Medical Terminology - Word Parts: c
Bacillary angiomatosis7
- Regnery R, Tappero J. Unraveling mysteries associated with cat-scratch disease, bacillary angiomatosis, and related syndromes . (cdc.gov)
- Because the 2 diseases may coexist, the lesions of bacillary angiomatosis may be easily overlooked. (medscape.com)
- Bacillary angiomatosis, however, causes a vascular proliferation, not a formation of stellate abscesses without granuloma formation, as found in cat scratch disease. (medscape.com)
- In addition, unlike patients with bacillary angiomatosis, those with cat scratch disease do not respond to antibiotics. (medscape.com)
- Molecular detection of Bartonella henselae for the diagnosis of cat scratch disease and bacillary angiomatosis of the conjunctiva. (medscape.com)
- 10. [Bartonella (Rochalimaea) infections: cat-scratch disease and bacillary angiomatosis]. (nih.gov)
- 19. [Cat-scratch disease and bacillary angiomatosis. (nih.gov)
Fever29
- Examples for such infections include human granulocytic ehrlichiosis ( Anaplasma phagocytophilum ), cat-scratch disease (CSD, Bartonella henselae ), and Q fever ( Coxiella burnetii ). (cdc.gov)
- Typically, CSD is a benign and self-limiting disease in humans, occurring with lymphadenopathy, low-grade fever, primary cutaneous inoculation lesion, and weight loss, lasting 6-12 weeks. (cdc.gov)
- In humans, C. burnetii infection usually is asymptomatic (60%) or manifests as a mild disease with fever, headache, myalgias, and spontaneous recovery ( 5 ). (cdc.gov)
- Can My Cat Make Me Sick with Cat Scratch Fever? (purina.ca)
- Cat scratch fever, sometimes referred to as cat scratch disease, is one of a handful of illnesses known as zoonotic diseases that can (although rarely do) spread from animals to humans. (purina.ca)
- Around 40% of all cats carry the cat scratch fever bacteria - Bartonella henselae - at some point in their lives, usually during kittenhood, according to the U.S. Centers for Disease Control and Prevention (CDC). (purina.ca)
- Cat scratch fever itself is incredibly rare, and it is even rarer that the disease is fatal for cats or humans. (purina.ca)
- Cats become infected with the bacteria that causes cat scratch fever after being bitten by fleas that carry it. (purina.ca)
- In some cases (albeit rare), people have acquired cat scratch fever from the direct bite of a flea or tick carrying the Bartonella henselae bacteria. (purina.ca)
- And while the animal-to-person route of transmission is well-documented and a real concern, person-to-person contact of cat scratch fever is not possible. (purina.ca)
- Cats usually display no symptoms of cat scratch fever. (purina.ca)
- Luckily, cat scratch fever is rarely cause for serious concern, and treatment is not typically necessary. (purina.ca)
- Most cat scratch fever infections are benign, disappearing on their own after a few months. (purina.ca)
- People who exhibit symptoms of cat scratch fever and experience high fever and pain should see a doctor right away. (purina.ca)
- Cats rarely become sick from cat scratch fever. (purina.ca)
- Among cats, the most at-risk populations for cat scratch fever are kittens and strays or feral cats. (purina.ca)
- Moreover, cats living in warmer regions are more susceptible to cat scratch fever because the warmer the climate, the better the conditions for fleas to reproduce. (purina.ca)
- Among humans, cat scratch fever is more often seen in children up to age six and in people with immune systems weakened by disease or age. (purina.ca)
- According to sources, people are at the highest risk of becoming seriously sick from cat scratch fever if they have HIV, AIDS, diabetes or cancer, or if they are pregnant or the recipient of a transplanted organ. (purina.ca)
- Cat scratch fever is not the only disease that can be passed from your pet to human hosts. (purina.ca)
- Rickettsial and chlamydial diseases include Rocky Mountain spotted fever, Q-fever, and ornithosis. (cdc.gov)
- Cat-scratch disease and trench fever are forms of bartonellosis caused by different Bartonella species infecting humans. (scitechdaily.com)
- Her current work focuses on teaching physicians in other areas of the country about Rocky Mountain spotted fever (RMSF), a potentially lethal, tickborne rickettsial disease. (cdc.gov)
- This branch conducts research, investigates outbreaks, and implements public health interventions related to RMSF and other diseases such as ehrlichiosis, anaplasmosis, Q fever, typhus, and cat scratch disease. (cdc.gov)
- Do you need antibiotics for cat scratch fever? (mattstillwell.net)
- Is amoxicillin good for cat-scratch fever? (mattstillwell.net)
- If a cat bite breaks your skin, you should seek medical attention if: you start having any serious symptoms of an infection, such as fever, chills, pus or fluid oozing from the wound, or swollen lymph nodes. (mattstillwell.net)
- Your risk for developing cat-scratch fever may also be higher if you've been around a cat infested with fleas. (mattstillwell.net)
- Diseases that move through animal bites or scratches include bacteria like Bartonella that cause cat scratch fever, viruses that cause rabies, or diseases like ringworm that are caused from fungi. (cdc.gov)
Infections12
- However, most infections never progress to the full-blown "cat scratch disease," as a result, many are not aware of its existence. (askdrwong.ca)
- Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the infectious diseases society of america. (medscape.com)
- Infections are potentially transmitted from domestic animals to humans by scratches, bites, or close contact. (cdc.gov)
- 3. [Cat-scratch disease and other infections caused by Bartonella species]. (nih.gov)
- 4. [Cat scratch disease and associated infections]. (nih.gov)
- 20. Bartonella (Rochalimaea) infections: beyond cat scratch. (nih.gov)
- Because cat bites can become infected quickly, and those infections can spread rapidly, it's imperative to seek medical attention immediately following a cat bite or a cat scratch. (mattstillwell.net)
- Skin disease and ear infections are another common bacterial infection seen in cats. (cats.com)
- Cats commonly suffer from infections in their mouths, particularly if they have had untreated dental disease for some time. (cats.com)
- Lower urinary tract infections such as bladder infections (also called cystitis) in cats may cause frequent urination in unusual places, blood in the urine, and pain when urinating, which may cause your cat to cry out. (cats.com)
- However, your cat could also suffer from bacterial infections of the blood, immune system, bones and joints, and other organs such as the heart and brain. (cats.com)
- Bacterial infections can occur in healthy cats of any age, as your cat encounters thousands of bacteria every day. (cats.com)
Bacterial infection7
- Cat scratch disease (CSD) is a bacterial infection spread by cats. (cdc.gov)
- Cat scratches and bites can cause cat scratch disease, a bacterial infection carried in cat saliva. (jghdelhi.net)
- This bacterial infection can be passed to humans through a cat's claws or teeth when it breaks the skin by scratching or biting. (purina.ca)
- A self-limiting bacterial infection of the regional lymph nodes caused by AFIPIA felis, a gram-negative bacterium recently identified by the Centers for Disease Control and Prevention and by BARTONELLA HENSELAE . (nih.gov)
- Swollen glands (lymph nodes) that develop within a week involving an area of the body that was scratched can be an indication of a bacterial infection. (mattstillwell.net)
- A good cleaning and perhaps antibiotic ointment often takes care of the wound, but sometimes, these bites and scratches can result in a bacterial infection. (mattstillwell.net)
- However, if your cat encounters a harmful or pathogenic bacteria, they can multiply within your cat's body resulting in a bacterial infection. (cats.com)
Bite or scratch3
- If the bite or scratch gets infected or if you have symptoms of CSD, call your doctor. (medlineplus.gov)
- The germ spreads to people when infected cats bite or scratch a person hard enough to break their skin. (cdc.gov)
- Conclusion: Amoxicillin can be used as a prophylactic antibiotic in dog and cat bite or scratch wounds, and there is no significant difference in infection rate from amoxicillin-clavulanate. (mattstillwell.net)
Zoonotic diseases1
- Her other recent projects include an investigation of zoonotic diseases in the Great Smokey Mountains National Park, an RMSF prevention project in Arizona, and a chart review of severe and fatal cases of RMSF. (cdc.gov)
Enlarged lymph1
- An enlarged lymph node in the armpit region of a person with cat scratch disease, and partially healed wounds from a cat scratch on the hand. (cdc.gov)
Bartonella henselae Infection1
- 12. Beyond cat scratch disease: widening spectrum of Bartonella henselae infection. (nih.gov)
Bites and scratches1
- Wash cat bites and scratches well with soap and running water. (cdc.gov)
Humans9
- Bartonella organisms remain viable in flea feces, and transmission to humans results in inoculation of B. henselae -contaminated flea feces into the skin through a scratch ( 3 ). (cdc.gov)
- However, transmission of B. henselae from cats to humans through scratches is rare ( 4 ). (cdc.gov)
- After 1 year of age, the cat is less likely to infect humans. (askdrwong.ca)
- However, these animals can serve as reservoirs for the agents of important bacterial infectious diseases and as a potential source of infection for humans, even though the infectious animals may be asymptomatic. (cdc.gov)
- Bacteria of the genus Bartonella are parasites that can be transmitted to humans via insect bites and animal scratches, resulting in an infection known as "bartonellosis. (scitechdaily.com)
- Even if your cat doesn't go outside, just like with fleas, humans and dogs may bring them in and they can easily move over to cats if they are in close proximity. (hartz.com)
- Can humans take cat amoxicillin? (mattstillwell.net)
- One Health recognizes that the three sectors, that is, people, animals, and the environment, are closely connected to each other, and that movement of diseases from animals to humans can be influenced by changes in the environment they share. (cdc.gov)
- Carol Rubin] There are many diseases that people can get directly from cats and dogs, and there are also some diseases that can be transmitted by insects, such as mosquitoes or sand flies that first bite the cat or dog and then transmit the disease when they bite humans. (cdc.gov)
Centers4
- The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
- Joanna Regan, MD, MPH, FAAP is a pediatrician who currently works as a medical epidemiologist in the Rickettsial Zoonoses Branch of the Centers for Disease Control and Prevention. (cdc.gov)
- Announcer] This program is presented by the Centers for Disease Control and Prevention. (cdc.gov)
- Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. (cdc.gov)
Cat's3
- Rubbing the eyes after petting a cat's fur can also spread cat scratch disease. (jghdelhi.net)
- The route to human transmission of the Bartonella henselae bacteria occurs when this bacteria becomes trapped beneath the cat's claws or in its teeth, usually from the cat cleaning itself, scratching, or fighting with other infected cats, and then the cat scratches or bites the human, breaking the skin. (purina.ca)
- Most of these bacteria are harmless, and your cat's immune system will protect them from many of those that can cause disease. (cats.com)
Lymphadenopathy4
- Bartonella henselae is the causative agent of cat-scratch disease (CSD), the most common cause of lymphadenopathy in adults and children ( 1 ). (cdc.gov)
- Lymphadenopathy associated with cat-scratch disease in a child. (bvsalud.org)
- Although cat-scratch disease is also associated with cats, it presents with regional lymphadenopathy rather than the linear pattern of skin nodules seen in sporotrichosis. (aafp.org)
- If an antibiotic is chosen to treat cat-scratch disease, azithromycin (Zithromax) appears to be effective at reducing the duration of lymphadenopathy. (mattstillwell.net)
Emerging Infectio3
Swollen1
- Later, the person's lymph nodes near the original scratch or bite can become swollen, tender, or painful. (cdc.gov)
Diagnosis4
- Diagnosis of "cat scratch disease" depends on a history of scratch or bite from a cat, as well as the typical progression of illness. (askdrwong.ca)
- Readers should not consider the report or any part of it to be guidance or instruction regarding the diagnosis, care, or treatment of tick-borne diseases or to supersede in any way existing guidance. (hhs.gov)
- The differential diagnosis includes other granulomatous diseases or diseases with lymphangitic spread, including atypical mycobacterioses (i.e. (aafp.org)
- The differential diagnosis of an acute disease of the spinal cord includes many conditions [6,7]. (who.int)
Fleas10
- By scratching and biting at the fleas, cats pick up the infected flea dirt under their nails and between their teeth. (cdc.gov)
- Check for fleas by using a flea comb on your cat to inspect for flea dirt. (cdc.gov)
- They can also develop the condition if the droppings from infected fleas get into wounds or scratches on the body. (purina.ca)
- cat fleas appear to be the most common vectors. (cdc.gov)
- Indoors or outdoors, your cat may be at risk for fleas and ticks. (hartz.com)
- If you have a dog, your dog may carry fleas to your cat. (hartz.com)
- Common areas to find ticks (and fleas) on your cat are inside and behind the ears, under the legs, around the groin, around the neck and shoulders, and between the toes. (hartz.com)
- Failing to protect your cat from fleas and ticks can result not only in uncomfortable and unhealthy conditions for the animal, but also potential infestations within your home. (hartz.com)
- Even if you get rid of the fleas on your cat, as your cat moves around your home, these eggs can fall off and end up on your furniture and carpet. (hartz.com)
- Protecting your cat and home against fleas and ticks with Hartz® UltraGuard® products will enable you and your pet to enjoy the warm, sunny weather without the worry of troublesome pests. (hartz.com)
Lymph nodes1
- Affected lymph nodes usually are proximal to the site of a cat scratch or bite, frequently are tender, and may suppurate. (cdc.gov)
Rickettsial Diseases2
Center for Infectious Diseases1
- The Center for Infectious Diseases: Toward the National Foundation for Infectious Diseases, 1981. (cdc.gov)
Henselae7
- Cat scratch disease (CSD) is an illness caused by the bacterium Bartonella henselae. (medlineplus.gov)
- Most cats with B. henselae infection show NO signs of illness, but on rare occasions this disease can cause inflammation of the heart-making cats very sick with labored breathing. (cdc.gov)
- B henselae and B quintana may stain positively with a specific antiserum against the cat scratch bacillus. (medscape.com)
- We report that cat or dog ownership is not associated with an increased seroprevalence of antibodies to Anaplasma phagozytophilum , Coxiella burnetii , and Bartonella henselae in symptom-free persons in Styria, Austria. (cdc.gov)
- 9. [Bartonella henselae, an ubiquitous agent of proteiform zoonotic disease]. (nih.gov)
- 11. Bartonella henselae-mediated disease in solid organ transplant recipients: two pediatric cases and a literature review. (nih.gov)
- Previous studies on Bartonella henselae (B. henselae for short), the bacterium responsible for the cat-scratch disease, have shown that it can directly "inject" proteins that inhibit programmed cell death (apoptosis) into the endothelial cells. (scitechdaily.com)
Bartonellosis2
Symptoms of cat scratch3
- Contact your doctor if you develop any symptoms of cat scratch disease or infection. (cdc.gov)
- What are the symptoms of cat scratch disease? (jghdelhi.net)
- The symptoms of cat scratch disease may resemble other conditions or medical problems. (jghdelhi.net)
Kittens3
- Kittens are also more likely to scratch and bite while they play and learn how to attack prey. (cdc.gov)
- Young kittens younger than 1 year of age are more likely to scratch, increasing the likelihood of infection. (jghdelhi.net)
- It is quite possible that at least part of the reason is the playfulness of young kittens biting and scratching their owners. (askdrwong.ca)
Fungal1
- Fungal diseases are mostly confined to farm workers, outdoor workers, and animal breeders. (cdc.gov)
Infectious Disease7
- An old and a new infectious disease with common etiology? (nih.gov)
- C9229 Systemic Disorder C128453 Pediatric Infectious Disease Terminology C34578 Acute Disseminated Encephalomyelitis Acute Disseminated Encephalomyelitis ADEM An inflammatory process affecting the central nervous system. (nih.gov)
- C34580 Encephalomyelitis C128453 Pediatric Infectious Disease Terminology C128379 Acute Flaccid Myelitis Acute Flaccid Myelitis An acute onset of focal limb weakness that is associated mainly with gray matter abnormalities or CSF pleocytosis, but which is without an apparent cause. (nih.gov)
- C96411 Pediatric Viral Infection C128453 Pediatric Infectious Disease Terminology C128411 Acute Sinusitis Acute Sinusitis Sinusitis lasting less than or equal to thirty days. (nih.gov)
- C128453 Pediatric Infectious Disease Terminology C128378 Acute Transverse Myelitis Acute Transverse Myelitis A neurologic disorder that is caused by inflammation across both sides of one level, or segment, of the spinal cord. (nih.gov)
- from NINDS) C128453 Pediatric Infectious Disease Terminology C128344 Adult Intestinal Botulism Adult Intestinal Botulism Adult Intestinal Toxemia Botulism A rare form of botulism that occurs among adults by the same mechanism as infant botulism. (nih.gov)
- C128453 Pediatric Infectious Disease Terminology C84541 African Trypanosomiasis African Trypanosomiasis A parasitic disorder caused by protozoa of the Trypanosoma brucei species. (nih.gov)
Viral diseases2
Syndromes1
- 1. Cat-scratch disease and related clinical syndromes. (nih.gov)
Infection called1
- Yes, it is possible to pick up an infection called "cat scratch disease" from the kitten. (askdrwong.ca)
Licks2
- The disease spreads when an infected cat licks a person's open wound, or bites or scratches a person hard enough to break the surface of the skin. (cdc.gov)
- The bacteria are passed from a cat to a human after the cat licks its paws then scratches human skin. (jghdelhi.net)
Site of the scratch2
Antibiotics2
- Should cat scratches be treated with antibiotics? (mattstillwell.net)
- Cat scratch disease can be treated by antibiotics. (mattstillwell.net)
20212
- The Prevention and Treatment Subcommittee of the 2021-2022 Tick-Borne Disease Working Group convened to address advances and gaps in the prevention and treatment of tick-borne diseases (TBDs). (hhs.gov)
- During the public meeting on August 26, 2021, the Tick-Borne Disease Working Group selected Dennis M. Dixon, a federal representative, and Sunil K. Sood, a public representative, to serve as co-chairs of the Disease Prevention and Treatment Subcommittee. (hhs.gov)
Epidemiology1
- 5. Cat-scratch disease: epidemiology, aetiology and treatment. (nih.gov)
Arboviruses1
- The investigators stated that although by 2004, with the aid of federal funding, well-developed West Nile virus surveillance systems existed in almost every state, by 2012, following a 61% decrease in federal funding, many health departments had reduced such surveillance and lacked a systematic, disease-based surveillance system for other arboviruses. (medscape.com)
Wash4
- If you do get a scratch or bite, wash it well with soap and water. (medlineplus.gov)
- Wash your hands with soap and running water after playing with your cat, especially if you live with young children or people with weakened immune systems. (cdc.gov)
- If there is any scratch or bite, immediately wash the wound with soap and water. (askdrwong.ca)
- If you are scratched or bitten by a cat or kitten, it is important to promptly wash the area with soap and water. (mattstillwell.net)
Feline1
- These cats should be checked for ticks on a daily basis, or else they are at risk for serious illnesses such as Lyme disease or feline infectious anemia transmitted by tick bites. (hartz.com)
Acute disease1
- However, this infection may lead to serious complications and even death in patients with acute disease, especially those with meningoencephalitis and myocarditis and, more frequently, in chronically infected patients with endocarditis. (cdc.gov)
Flea2
Pediatric1
- Understanding common, and some not so common symptoms of pediatric diseases can help make sure that your kids get diagnosed and treated quickly. (keepkidshealthy.com)
20201
- The 2018 Report to Congress focused primarily on Lyme disease, while the 2020 Report to Congress was expanded to include more discussion of the other TBDs. (hhs.gov)
Common3
- Cat scratch disease is believed to be fairly common. (askdrwong.ca)
- Common sources of infection include contaminated food (particularly raw meat) or water, or contact with another infected cat. (cats.com)
- What these serious diseases have in common is that they all start as zoonoses in the animal kingdom. (cdc.gov)
Lyme1
- Care was made to include members with different perspectives on Lyme disease treatment, because that issue has consistently shown to generate divergent opinions in previous Tick-Borne Disease Working Group reports. (hhs.gov)
Feces1
- Toxoplasmosis is associated with the handling of cat feces, but skin lesions are uncommon and do not usually show a linear distribution. (aafp.org)
Occur2
Human2
- Health is especially important now because we live in a time when there is an increase in the number of new diseases that affect human health. (cdc.gov)
- One Health is an approach to looking at new diseases and other adverse health events by taking a holistic viewpoint that considers human health, animal disease, and environmental changes. (cdc.gov)
Treatment1
- Your veterinarian can tell you whether your cat requires testing or treatment. (cdc.gov)
Illness1
- the disease can thus be considered a foodborne illness . (wikipedia.org)