Carticaine: A thiophene-containing local anesthetic pharmacologically similar to MEPIVACAINE.Anesthesia, Dental: A range of methods used to reduce pain and anxiety during dental procedures.Dental Implant-Abutment Design: The plan and delineation of DENTAL IMPLANT fitting with DENTAL ABUTMENT.Dental Pulp Test: Investigations conducted on the physical health of teeth involving use of a tool that transmits hot or cold electric currents on a tooth's surface that can determine problems with that tooth based on reactions to the currents.Molar: The most posterior teeth on either side of the jaw, totaling eight in the deciduous dentition (2 on each side, upper and lower), and usually 12 in the permanent dentition (three on each side, upper and lower). They are grinding teeth, having large crowns and broad chewing surfaces. (Jablonski, Dictionary of Dentistry, 1992, p821)Denture, Partial: A denture replacing one or more (but not all) natural teeth. It is supported and retained by underlying tissue and some or all of the remaining teeth.Prilocaine: A local anesthetic that is similar pharmacologically to LIDOCAINE. Currently, it is used most often for infiltration anesthesia in dentistry.Anesthetics, Local: Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.Anesthesia, Local: A blocking of nerve conduction to a specific area by an injection of an anesthetic agent.Commerce: The interchange of goods or commodities, especially on a large scale, between different countries or between populations within the same country. It includes trade (the buying, selling, or exchanging of commodities, whether wholesale or retail) and business (the purchase and sale of goods to make a profit). (From Random House Unabridged Dictionary, 2d ed, p411, p2005 & p283)Anesthesia, General: Procedure in which patients are induced into an unconscious state through use of various medications so that they do not feel pain during surgery.Cyclamen: A plant genus of the family PRIMULACEAE that contains triterpenoid saponins.Anesthesia, Conduction: Injection of an anesthetic into the nerves to inhibit nerve transmission in a specific part of the body.Mepivacaine: A local anesthetic that is chemically related to BUPIVACAINE but pharmacologically related to LIDOCAINE. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)Encyclopedias as Topic: Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)ThiophenesPatents as Topic: Exclusive legal rights or privileges applied to inventions, plants, etc.Drugs, Generic: Drugs whose drug name is not protected by a trademark. They may be manufactured by several companies.Biological Transport, Active: The movement of materials across cell membranes and epithelial layers against an electrochemical gradient, requiring the expenditure of metabolic energy.Iontophoresis: Therapeutic introduction of ions of soluble salts into tissues by means of electric current. In medical literature it is commonly used to indicate the process of increasing the penetration of drugs into surface tissues by the application of electric current. It has nothing to do with ION EXCHANGE; AIR IONIZATION nor PHONOPHORESIS, none of which requires current.Electrodes: Electric conductors through which electric currents enter or leave a medium, whether it be an electrolytic solution, solid, molten mass, gas, or vacuum.Membranes, Artificial: Artificially produced membranes, such as semipermeable membranes used in artificial kidney dialysis (RENAL DIALYSIS), monomolecular and bimolecular membranes used as models to simulate biological CELL MEMBRANES. These membranes are also used in the process of GUIDED TISSUE REGENERATION.Polymers: Compounds formed by the joining of smaller, usually repeating, units linked by covalent bonds. These compounds often form large macromolecules (e.g., BIOPOLYMERS; PLASTICS).Pharmaceutical Preparations: Drugs intended for human or veterinary use, presented in their finished dosage form. Included here are materials used in the preparation and/or formulation of the finished dosage form.Eosine I Bluish: A red fluorescein dye used as a histologic stain. It may be cytotoxic, mutagenic, and inhibit certain mitochondrial functions.Cosmetic Techniques: Procedures for the improvement or enhancement of the appearance of the visible parts of the body.Rejuvenation: The phenomenon of youthfulness, vitality, and freshness being restored. This can apply to appearance, TISSUES, organ functions, or other areas.Skin Aging: The process of aging due to changes in the structure and elasticity of the skin over time. It may be a part of physiological aging or it may be due to the effects of ultraviolet radiation, usually through exposure to sunlight.Hyaluronic Acid: A natural high-viscosity mucopolysaccharide with alternating beta (1-3) glucuronide and beta (1-4) glucosaminidic bonds. It is found in the UMBILICAL CORD, in VITREOUS BODY and in SYNOVIAL FLUID. A high urinary level is found in PROGERIA.Foreign-Body Reaction: Chronic inflammation and granuloma formation around irritating foreign bodies.Dermatologic Agents: Drugs used to treat or prevent skin disorders or for the routine care of skin.Illusions: The misinterpretation of a real external, sensory experience.Defibrillators, Implantable: Implantable devices which continuously monitor the electrical activity of the heart and automatically detect and terminate ventricular tachycardia (TACHYCARDIA, VENTRICULAR) and VENTRICULAR FIBRILLATION. They consist of an impulse generator, batteries, and electrodes.Prostheses and Implants: Artificial substitutes for body parts, and materials inserted into tissue for functional, cosmetic, or therapeutic purposes. Prostheses can be functional, as in the case of artificial arms and legs, or cosmetic, as in the case of an artificial eye. Implants, all surgically inserted or grafted into the body, tend to be used therapeutically. IMPLANTS, EXPERIMENTAL is available for those used experimentally.Radio Frequency Identification Device: Machine readable patient or equipment identification device using radio frequency from 125 kHz to 5.8 Ghz.Pacemaker, Artificial: A device designed to stimulate, by electric impulses, contraction of the heart muscles. It may be temporary (external) or permanent (internal or internal-external).Electromagnetic Radiation: Waves of oscillating electric and MAGNETIC FIELDS which move at right angles to each other and outward from the source.OregonRheumatic Diseases: Disorders of connective tissue, especially the joints and related structures, characterized by inflammation, degeneration, or metabolic derangement.Ophthalmology: A surgical specialty concerned with the structure and function of the eye and the medical and surgical treatment of its defects and diseases.Bibliometrics: The use of statistical methods in the analysis of a body of literature to reveal the historical development of subject fields and patterns of authorship, publication, and use. Formerly called statistical bibliography. (from The ALA Glossary of Library and Information Science, 1983)Public-Private Sector Partnerships: An organizational enterprise between a public sector agency, federal, state or local, and a private sector entity. Skills and assets of each sector are shared to deliver a service or facility for the benefit or use of the general public.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.Publications: Copies of a work or document distributed to the public by sale, rental, lease, or lending. (From ALA Glossary of Library and Information Science, 1983, p181)Bupivacaine: A widely used local anesthetic agent.Amides: Organic compounds containing the -CO-NH2 radical. Amides are derived from acids by replacement of -OH by -NH2 or from ammonia by the replacement of H by an acyl group. (From Grant & Hackh's Chemical Dictionary, 5th ed)Central Nervous System: The main information-processing organs of the nervous system, consisting of the brain, spinal cord, and meninges.Stereoisomerism: The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)Spectrum Analysis: The measurement of the amplitude of the components of a complex waveform throughout the frequency range of the waveform. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)User-Computer Interface: The portion of an interactive computer program that issues messages to and receives commands from a user.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.RNA, Ribosomal, 16S: Constituent of 30S subunit prokaryotic ribosomes containing 1600 nucleotides and 21 proteins. 16S rRNA is involved in initiation of polypeptide synthesis.DNA, Ribosomal: DNA sequences encoding RIBOSOMAL RNA and the segments of DNA separating the individual ribosomal RNA genes, referred to as RIBOSOMAL SPACER DNA.Software: Sequential operating programs and data which instruct the functioning of a digital computer.Base Composition: The relative amounts of the PURINES and PYRIMIDINES in a nucleic acid.

Comparison of articaine and bupivacaine/lidocaine for single medial canthus peribulbar anaesthesia. (1/44)

In a single-centre, randomized, double-blind study, we compared the efficacy of 2% articaine with that of a mixture of 0.5% bupivacaine and 2% lidocaine for peribulbar anaesthesia in cataract surgery, using a single medial canthus injection technique. Eighty-two patients were allocated randomly to receive 7-9 ml of a mixture of 0.5% bupivacaine and 2% lidocaine or an equal volume of 2% articaine with 1:200,000 epinephrine. Hyaluronidase 30 iu ml(-1) was added to both solutions. The degree of akinesia was scored 1, 5 and 10 min after the block, at the end of surgery and at discharge from the day case unit. Primary outcome measures were the difference in ocular movement scores 5 min after block and the need for supplementary inferolateral injections. There was greater akinesia in the articaine group at 5 min (P=0.01). Ten patients (24%) in the articaine group and 21 patients (51%) in the bupivacaine/lidocaine group required a supplementary injection (P=0.02). The mean (SD) volume of local anaesthetic required to achieve adequate block for surgery was 9.7 (2.1) ml in the articaine group and 11.0 (2.2) ml in the bupivacaine/lidocaine group (P=0.01). There was a faster offset of akinesia after surgery in the articaine group (P=0.01). There were no differences between groups in the incidence of reported pain or of minor complications. In our study, 2% articaine with 1:200,000 epinephrine was safe and efficacious for single medial canthus peribulbar anaesthesia.  (+info)

Comparative study on anesthetic potency of dental local anesthetics assessed by the jaw-opening reflex in rabbits. (2/44)

The potency of 4 local anesthetics to dental pulp was compared. Drugs were 4% articaine with 12 microgram/mL epinephrine (A12), 4% articaine with 6 microgram/mL epinephrine (A6), 2% lidocaine with 12.5 microgram/mL epinephrine (L), and 3% propitocaine with 0.03 IU/mL felypressin (P). Local anesthetics were injected into the dental root of the mandibular incisor. Electromyogram (EMG) of the digastric muscle was measured during the jaw-opening reflex induced by electrical stimulation. The disappearance of the EMG wave was judged as positive evidence of anesthesia. The determination of ED50 of the anesthetic was made by probit analysis. The ED50 of the A12 was minimal in all the tested anesthetics throughout the entire course. The potency in the A6 was 2.8 times that of the L. The potency of the A12 at the 15-minute measurement was 3.8 times that of the A6. The ED50 of the P was higher compared with those of the other 3 groups. It was concluded that articaine showed quicker onset than lidocaine and propitocaine and that there was a need to increase the dosage to attain a quick onset or to extend the duration.  (+info)

Comparison of articaine and bupivacaine/lidocaine for peribulbar anaesthesia by inferotemporal injection. (3/44)

BACKGROUND: Articaine is a novel amide local anaesthetic with a shorter duration of action than prilocaine. METHODS: In a randomized, double-blind study we compared the efficacy of 2% articaine with epinephrine 1:200,000 with a mixture of 0.5% bupivacaine and 2% lidocaine with epinephrine 1:200,000 for peribulbar anaesthesia in cataract surgery using a single inferotemporal injection. Eighty-two patients were randomly allocated to one of two groups to receive peribulbar anaesthesia with 6-7 ml of articaine or a bupivacaine/lidocaine mixture. Both solutions contained hyaluronidase 30 iu ml(-1). Ocular movement was scored at 2 min intervals up to 10 min, at the end of surgery and at time of discharge from hospital. Time to readiness for surgery and any complications (proptosis, chemosis, pain) were recorded. RESULTS: The articaine group demonstrated a rapid onset of peribulbar block with mean time (SD) to readiness for surgery of 4.2 (4.5) min compared with 7.2 (5.7) min in the bupivacaine/lidocaine group (P=0.0095). The block obtained in the articaine group was dense with eye movement scores at 2, 4, 6, 8 and 10 min all significantly reduced (P<0.01 at each interval). There was also a faster offset of the block in the articaine group (P=0.0009). There was no difference in incidence of minor complications between the groups. CONCLUSIONS: Two per cent articaine is safe and effective for peribulbar anaesthesia by inferotemporal injection and is a suitable alternative to the traditional mixture of 0.5% bupivacaine and 2% lidocaine.  (+info)

Comparison of articaine and bupivacaine/lidocaine for sub-Tenon's anaesthesia in cataract extraction. (4/44)

BACKGROUND: Articaine is the most widely used local anaesthetic for dental anaesthesia in Germany, Italy and The Netherlands and has recently been introduced and licensed for dental use in the UK. We have previously shown articaine to be superior to a standard mixture of bupivacaine 0.5%/lidocaine 2% for peribulbar anaesthesia. Sub-Tenon's anaesthesia arguably provides a safer method of anaesthetic delivery for cataract surgery. A blunt cannula is used in this technique, thus greatly reducing the risk of globe perforation, intrathecal injection and sight-threatening periocular haemorrhage. METHODS: We compared articaine and bupivacaine/lidocaine for sub-Tenon's anaesthesia in cataract surgery. RESULTS: Sub-Tenon's anaesthesia using articaine 2% resulted in a more rapid onset of motor block compared with a bupivacaine/lidocaine (P=0.0076). Ocular movement scores were significantly lower from 2 min after injection until the end of surgery (P=0.031 ANOVA). CONCLUSION: Articaine 2% is safe and effective for sub-Tenon's anaesthesia and is a suitable alternative to the traditional bupivacaine 0.5%/lidocaine 2% mixture.  (+info)

Articaine versus lidocaine plus bupivacaine for peribulbar anaesthesia in cataract surgery. (5/44)

BACKGROUND: We compared the efficacy and safety of articaine 2% with a mixture of lidocaine 2% and bupivacaine 0.5% without hyaluronidase for peribulbar anaesthesia in cataract surgery. METHOD: In this double-blind randomized clinical study, 58 cataract patients were allocated to receive either articaine 2% with epinephrine 1:200 000 or a mixture of equal parts of lidocaine 2% with epinephrine 1.25:100 000 and bupivacaine 0.5%. Ocular and eyelid movement scores, the number of supplementary injections, total volume of solution used and pain and complications during injection and surgery were used as clinical end-points. RESULTS: Articaine produced greater akinesia after 5 min (P=0.03). Eighteen patients (60%) in the articaine group and 26 (93%) in the lidocaine/bupivacaine group required a second injection (P=0.003). A third injection was needed by two patients (7%) in the articaine group and 12 (43%) in the lidocaine/bupivacaine group (P=0.001). The total mean volume of local anaesthetic required to achieve akinesia was mean 9.4 (SD 1.7) ml in the articaine group and 11.28 (1.86) ml in the lidocaine/bupivacaine group (P<0.001). Median pain score was lower in the articaine group than in lidocaine/bupivacaine group during injection (P=0.004) and surgery (P=0.014). There was no difference between the groups for the incidence of complications. CONCLUSION: Articaine 2% without hyaluronidase is more advantageous than a mixture of lidocaine 2% and bupivacaine 0.5% without hyaluronidase for peribulbar anaesthesia in cataract surgery.  (+info)

Comparison of effectiveness of 4% articaine associated with 1: 100,000 or 1: 200,000 epinephrine in inferior alveolar nerve block. (6/44)

This comparative study using 20 healthy volunteers evaluated the anesthetic efficacy of 4% articaine in association with 2 different concentrations of epinephrine, 1:200,000 (G1) and 1:100,000 (G2). The first premolars were tested with a pulp tester to verify the anesthesia induced by the inferior alveolar nerve block. The following parameters were measured: period of latency (PL; interval between the end of anesthetic injection and absence of response to the maximum output--80 reading--of the pulp tester); complete pulpal anesthesia (CPA; period in which the subject had no response to maximal output of the pulp tester 80 reading); partial anesthesia (PA; interval between the first reading below 80 and the return to basal levels); and the anesthesia of the soft tissues (AST; period of time from onset of anesthesia until the return to normal sensation of the lip). The Wilcoxon test (alpha = 0.05) was used to analyze the data. No significant difference was found regarding PL (P = .47), CPA (P = .88), PA (P = .46), and AST (P = .85). The results indicated that both solutions presented the same clinical effectiveness in blocking the inferior alveolar nerve.  (+info)

Comparative analysis of tissue reactions to anesthetic solutions: histological analysis in subcutaneous tissue of rats. (7/44)

Postanesthetic pain is a relatively common complication after local anesthesia. This complication may be caused by the anesthetic technique or by the anesthetic solution used. Tissue reactions induced by the anesthetic solutions may be one of the factors resulting in pain after anesthesia. The objective of this study was to comparatively analyze tissue reactions induced by different anesthetic solutions in the subcutaneous tissue of rats. The following solutions were utilized: 2% lidocaine without vasoconstrictor; a 0.5% bupivacaine solution with 1:200,000 adrenaline; a 4% articaine solution and 2% mepivacaine, both with 1:100,000 adrenaline; and a 0.9% sodium chloride solution as a control. Sterilized absorbent paper cones packed inside polyethylene tubes were soaked in the solutions and implanted in the subcutaneous region. The sacrifice periods were 1, 2, 5, and 10 days after surgery. The specimens were prepared and stained with hematoxylin and eosin for histological analysis. The results showed that there is a difference in tissue irritability produced by the local anesthetic solutions. The results also showed that there is no relation between the concentration of the drug and the inflammatory intensity, that the mepivacaine and articaine solutions promoted less inflammatory reaction than the bupivacaine, and that the lidocaine solution produced the least intense inflammation.  (+info)

Influence of different vehicles on the pH of calcium hydroxide pastes. (8/44)

The main known benefit of calcium hydroxide as an intracanal medicament lies in the bactericidal effect conferred by its pH. The objective of this work was to determine the influence of the vehicle on the pH of calcium hydroxide pastes after usage in patients and in vitro. The incisor root canals of 180 patients were instrumented and filled with calcium hydroxide pastes containing distilled water, chlorhexidine, propylene glycol, anesthetic solution, camphorated p-monochlorophenol and camphorated p-monochlorophenol-propylene glycol. The pH of the paste in the patients' root canals was measured at 7, 14 and 21 days. Similarly, pH was measured in vitro up to 21 days. The pH of all the pastes remained constant throughout the time periods assessed. The calcium hydroxide-water combination showed significantly higher pH values than the other pastes in clinical use. Comparative analysis showed that the pH values of the anesthetic solution, camphorated p-monochlorophenol and camphorated p-monochlorophenol-propylene glycol were significantly higher in vitro. The type of vehicle was shown to influence the final pH of the pastes. However, the alkalinity of all pastes was maintained over time under the experimental conditions.  (+info)

Regional Analysis of Global Articaine Hydrochloride Market:. Globally Europe is the largest market for Articaine Hydrochloride. The Europe market for articaine hydrochloride is expected to grow at a CAGR of 6.8% and is expected to reach at USD 599.6 Million by the end of the forecasted period.. North America is the second-largest market for articaine hydrochloride which is expected to grow at a CAGR of 7.2%. Asia pacific region is expected to be fastest growing region in articaine hydrochloride market.. About Market Research Future:. At Market Research Future (MRFR), we enable our customers to unravel the complexity of various industries through our Cooked Research Report (CRR), Half-Cooked Research Reports (HCRR), Raw Research Reports (3R), Continuous-Feed Research (CFR), and Market Research & Consulting Services.. MRFR team have supreme objective to provide the optimum quality market research and intelligence services to our clients. Our market research studies by products, services, ...
Local Anesthetic Articaine Hydrochloride Pharmaceutical Intermediate for Dental Local Anesthetic picture from Shenzhen Simeiquan Biotechnology Co., Ltd. view photo of Articaine Hydrochloride, Pharmaceutica Intermediates, Pharmaceutical Chemicals.Contact China Suppliers for More Products and Price.
Local Anesthetic Articaine Hydrochloride Pharmaceutical Intermediate for Dental Local Anesthetic picture from Shenzhen Simeiquan Biotechnology Co., Ltd. view photo of Articaine Hydrochloride, Pharmaceutica Intermediates, Pharmaceutical Chemicals.Contact China Suppliers for More Products and Price.
Dental Update is the leading dental journal for CPD (Continuing Professional Development) and education. Dental Update gives verifiable CPD and PDP management
Objectives: The aim of this study was to compare the onset and duration of pulpal anesthesia by maxillary infiltration using 2% lidocaine with 1:100,000 epinephrine, 4% articaine with 1:200,000 epinephrine, and 4% articaine with 1:100,000 epinephrine. Method and Materials: Twenty healthy patients randomly received 1.8 mL of one of the three local anesthetics during operative dentistry procedures of low complexity on three maxillary posterior teeth. Onset and duration were determined using an electric pulp tester. Results: The mean values for pulpal onset were 2.8, 1.6, and 1.4 minutes and for pulpal duration were 39.2, 56.7, and 66.3 minutes, respectively, for 2% lidocaine with 1:100,000 epinephrine, 4% articaine with 1:200,000 epinephrine, and 4% articaine with 1:100,000 epinephrine. Statistical analysis by the Kruskal-Wallis nonparametric test showed significant differences with better results (shorter onset and longer duration periods) for both articaine solutions compared with the lidocaine ...
When people inquire about the development of the Anutra Local Anesthetic Delivery System, I tell them about my father. As a medical anesthesiologist, he would ask, "Why dont dentists buffer?" I would explain that it is a complex process and just not feasible or cost effective for routine dental practice. Still, it got me thinking. After spending years exploring various options, I developed Anutra as a simple way to buffer local anesthetics - not just in dentistry, but in medicine, as well.. Since receiving approval in 2015, Anutra has won numerous awards and has been in the press quite a bit. It is exciting to see the rapid growth and traction Anutra has experienced, and I think the reason for our success is threefold. First, there are not many products that benefit the patient and practitioner equally. This system minimizes patients fear of dental injections, and an independent study shows that it adds approximately two hours of chairtime back into the dentists day because the buffered ...
Study design Using a crossover design, intraligamentary injections of 1.4 mL of 4% articaine with 1:100,000 epinephrine and of 1.4 mL of 2% lidocaine with 1:100,000 epinephrine were randomly administered with a computer-controlled local anesthetic delivery system, in a double-blind manner on the mesial and distal aspects of a mandibular first molar, at 2 separate appointments to 51 subjects. A pulp tester was used to test for anesthesia, in 2-minute cycles for 60 minutes, of the mandibular first and second molars and second premolar. Anesthesia was considered successful when 2 consecutive 80 readings (highest output) were obtained within 20 minutes ...
Articaine is used for pain control. Like other local anesthetic drugs, articaine causes a transient and completely reversible state of anesthesia
Articaine DFL is a medicine available in a number of countries worldwide. A list of US medications equivalent to Articaine DFL is available on the Drugs.com website.
Learn about the potential side effects of articaine/epinephrine. Includes common and rare side effects information for consumers and healthcare professionals.
Introduction. One of the major problems associated with the anesthetic procedure is the lack of tissue oxygenation. Hypotension, an adverse effect of anesthesia, increases the risk of morbidity and death as a result of diminished organ perfusion.. Hypotension is defined as systolic arterial blood pressure (SABP) , 80 mm Hg and is estimated to develop in 41% of anesthetized humans, in up to 32% of anesthetized dogs, and in up to 33% of anesthetized cats.. Strategies for correction of hypotension include IV administration of fluids, reduction or termination of anesthetic delivery, administration of adjunct anesthetic and analgesic agents to reduce the inspired volatile concentration, and administration of inotropes and other vasoactive drugs. However, every single therapeutic option should be preceded by a correct diagnosis of the problem.. For years the belief that fluid preload would prevent hypotension during anesthesia has been discharged. Throughout anesthesia, the origin of hypotension can ...
HANSAmed Limited - Canadas Dental Specialty Company, Canadas specialty pharmaceutical and Medical Device company, Ultracaine, Articaine, Articaine 4%, the original, local anesthetic, local anesthesia, 4% Articaine, Ultracain, Cook-wiate anesthetics, Lidocaine, Lidocaine 2%, Carbocaine 2%, Carbocaine 3%, Marcaine, Monoject Needles, ANESTAject Needles, Metal hub needles, plastic hub needles, topical anesthetics, medicom topical gels, sultan topes topical gels, uniject K-S Syrings, Uniject S-A Syringe, Cook-Waite Syringe
The maximum dose for the various local anesthetic solutions is between 70 mg to 500 mg for an average 70 kg (154 lb) patient. Of course, the maximum dose is dependent upon the age, weight and health of the patient, the type of solution used, and whether vasoconstrictor is present or not. These anesthetic agents are distributed in concentrations that are appropriate to their toxicity and their anesthesia producing qualities. In the US and Canada, the carpules (cartridges) that these drugs are distributed in contain 1.8 ml of solution. Articaine carpules contain 1.7 ml. In some other countries, particularly the UK, carpules may contain 2.2 ml.. Since people vary in age, weight and health, the maximum dose of any given drug that an individual can tolerate varies widely, however, an average maximum dose can be computed arithmetically. The maximum dose (for a normal adult weighing 154 pounds) for Articaine is 500 mg. The maximum dose for lidocaine and mepivicaine is 300 mg. The maximum dose of ...
The success of modern dentistry is largely due to the development and implementation in practice of new tools and methods that allow painlessly carry out long and large - scale interventions in the oral cavity. The most effective and safe way of anesthesia on an outpatient dental reception is local anesthesia (M. G. Panin, 1969; A. F. Bizyaev, 1998; S. F. Gritsuk 1998; S. A. Rabinovich, 2000; R. S. Brown, 1994; S. Malamed, 1994, 1997; etc.). For the time being. The most effective of them are recognized drugs created on the basis of articaine, due to the peculiarities of its pharmacokinetics and pharmacodynamics (H. Lemay, 1984; R. Rahn, 1996, S. Malamed, 1997; A. J. Petrikas, 1997; L. A. Grigoryants, A. P. Shafransky, 1999; E. V. Zoryan, E. N. Anisimova, 2002; S. A. Rabinovich et al., 2005, 2006; E. V. Zoryan, S. A. Rabinovich, 2005; S. A. Rabinovich, E. V. Zoryan, 2006; etc.). The articaine containing products produced by various foreign companies and is known for its proprietary trade names: al
3.4 cc 4% Articaine w/ Epi Perio implant checks - implant osseointegrated, no mobility. Restored with PFM Crown in Family Dentistry Pt is pleased and CC addressed! Depth Check Implant Placed Because there is some evidence to suggest that conventional loading is more successful, that would be my recommendation to the patient ...
Objectives: This study was carried out to study the efficacy and the anesthetic characters of using Articaine 4 % with 1:100,000 Epinephrine as a local anesthetic drug in surgical practice through inferior alveolar nerve block and comparing it with Lidocaine 2% with 1:100,000 Epinephrine. Materials and methods: Thirty patients in two groups, fifteen patients each, undergo extraction of impacted mandibular third molar, Inferior Alveolar Nerve block had been carried out using either Articaine 4% or Lidocaine 2% Local anesthetic drugs. Results: Articaine was well-tolerated and it provided clinically effective pain relief during surgical procedures and it was as potent as Lidocaine and provided similar clinical effect to Lidocaine (Gold standard). Conclusions: On the basis of our findings, we recommend using Articaine 4% as local anesthetic drug in minor oral surgery
Dental anesthesia (or dental anaesthesia) is a field of anesthesia that includes not only local anesthetics but sedation and general anesthesia. The most commonly used local anesthetic is lidocaine (also called xylocaine or lignocaine), a modern replacement for procaine (also known as novocaine). Its half-life in the body is about 1.5-2 hours. Other local anesthetic agents in current use include articaine (also called septocaine or ubistesin), bupivacaine (a long-acting anesthetic), and mepivacaine. A combination of these may be used depending on the situation. Also, most agents come in two forms: with and without epinephrine (adrenaline) or other vasoconstrictor that allow the agent to last longer and also controls bleeding in the tissue during procedures. Usually the case is classified using the ASA Physical Status Classification System before any anesthesia is given. Nerve block - a common form of local dental anesthesia; blocks the reception of pain in one region of the mouth at a time. ...
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What you need to know about dental anesthesia. Find a local dentist near you for the comfortable anxiety free dental care youve always wanted. Learn about conscious sedation, IV sedation, dental anesthesia, sleep dentist and how to sleep through your next dental appointment without fear or anxiety. Ask how you can combine cosmetic dentistry with sedation for the smile youve always wanted. Find a sedation dentist in your area with cost saving offers and dental patient financing options for adults and teens.
Your baby will measure between 18-22 inches at birth. The core muscles can help to prevent falls and injuries that are more common during pregnancy and make delivery shorter and easier. Usually, the first day of the last menstrual period commences the nine months duration of pregnancy. This ovum would then travel through the Fallopian tubes dental anesthesia and pregnancy to the uterus. so tiny. Ask family members or friends dentql help prrgnancy housework, cooking, and shopping. Blood on toothbrush - Gross I know, but your body ramps up blood production while preggo which makes even healthy gums much more susceptible to bleeding. The embryo will have a very simply circulatory system and heart and will start to develop buds that will eventually grow into arms and legs. Females have a pair of ovaries located on each side of the uterus. Although I havent done dental anesthesia and pregnancy blood test, but I am sure the baby is there. If youre slipping away to visit the ladies room all night, ...
... The 2017 U.S. Dental anesthesia services sold through Offices of dentists-Product & - Market research report and industry analysis - 10889176
Dental Anesthesia is the field of anesthesia which includes Local Anesthetics but sedation and general anesthetics. Lidocaine is the most commonly used ane
Six-year-old Caleb Sears: His death was preventable. Im not a pediatric anesthesiologist. Most of us in anesthesiology - even those who take care of children in the operating room or the ICU every day - probably will never give anesthesia to a child in a dentists or oral surgeons office. So why should we care what happens there? Dental anesthesia permits and regulations, after all, are under the authority of state dental boards, not medical boards.. The reason we should care is that healthy children have died under anesthesia in dental office settings, children like Marvelena Rady, age 3, and Caleb Sears, age 6. Unfortunately, they arent the first children to suffer serious complications or death in our state after dental procedures under sedation or general anesthesia, and unless California laws change, they wont be the last.. In 2016, officers and past presidents of the California Society of Anesthesiologists (CSA) have made multiple trips to meetings of the Dental Board of California ...
Our dentist office offers a referral rewards program to our patients in Albany, NY. You receive points for each person you refer to us & each point has a $50 value. Redeem on any procedure, including dental anesthesia & sedation dentistry procedures. Call us today to learn more!
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FAQs - Dental Anesthesia Support Group - Dental Health. Discuss with people facing the same health challenges as yours and seek online advice from experts.
Dental Anesthesia Support Group - Dental Health. Discuss with people facing similar health challenges as yours. Seek advice from our online experts.
Articaine is a dental amide-type local anesthetic. It is the most widely used local anesthetic in a number of European countries and is available in many countries around. It is the only local anaesthetic to contain a thiophene ring, meaning it can be described as thiophenic; this conveys lipid solubility. This drug was first synthesized by Rusching in 1969, and brought to the market in Germany by Hoechst AG, a life-sciences German company, under the brand name Ultracain. This drug was originally referred to as "carticaine" until 1984. In 1983 it was brought into the North American market, to Canada, under the name Ultracaine for dental use, manufactured in Germany and distributed by Hoechst-Marion-Roussel. This brand is currently manufactured in Germany by Sanofi-Aventis and distributed in North America by Hansamed Limited (since 1999). After Ultracaines patent protection expired, new generic versions arrived to the Canadian market: (in order of appearance) Septanest (Septodont), Astracaine, ...
A published study that appeared in the Journal of Oral and Maxillofacial Surgery in October 2017, showed that buffered 1% lidocaine with epinephrine can be equally as effective as 2% lidocaine with epinephrine for a maxillary field block. This independent study by the University of North Carolina, Chapel Hill, found that buffering 1% lidocaine with epinephrine 1:100,000 with the Anutra Local Anesthetic Delivery System®, "reduces the pain on injection with a maxillary field block and results in similar lengths of pulpal anesthesia tested with a cold stimulus" as compared to the traditionally used 2% lidocaine with epinephrine 1:100,000 ...
NEW! A supplement to the 3-DVD set covers the local anesthetic ON and OFF switches, as well as Computer-Controlled Local Anesthetic Delivery (C-CLAD), allowing you to deliver intraoral local anesthetics painlessly in all areas of the oral cavity including the palate ...
NEW! A supplement to the 3-DVD set covers the local anesthetic ON and OFF switches, as well as Computer-Controlled Local Anesthetic Delivery (C-CLAD), allowing you to deliver intraoral local anesthetics painlessly in all areas of the oral cavity including the palate ...
Use: The Aisys and Avance Anesthesia Systems are prescription devices used in healthcare settings under the supervision of a physician. They are intended to provide general inhalation anesthesia and ventilation support to a wide range of patients. These devices are intended for volume or pressure control ventilation.. Recalling Firm:. GE Healthcare, LLC. 3000 N Grandview Blvd.. Waukesha, Wisconsin 53188-1615. Reason for Recall: A specific lot of GE Healthcare Aisys and Avance machines control board wiring harnesses have a defect, which can cause the machine to unexpectedly shut down, terminating ventilation, anesthetic delivery, and potentially patient monitoring.. Public Contact: If you need assistance or have questions about this recall or your GE Healthcare Aisys or Avance Anesthesia Systems, call GE Healthcare Customer Service, available 8:30am â?" 5:00 pm, Monday through Friday, at 1-800-654-0118 or at (262) 544-3894.. FDA District: Minneapolis. FDA Comments: Customers were sent a GE ...
Utilizing modified locations, methods and anesthetics quick and complete anesthesia can be achieved reducing your stress and chair time.
Ambulatory Anesthesia for Dentistry based in New York. Our practice is dedicated to improving the oral health of our patients by maintaining the highest regards to safety, comfort, and quality.
I have some claims for anesthesia provided for dental procedures that have been denied by Iowa Medicaid. I know they have 6 criteria that need to be m
Our Toronto dentists offer a comprehensive range of general and restorative dental services, as well as oral surgery and gum therapy.
There are issues often common among kids. Understandably, its all about dental complications. At times, some patients are seen acting awkwardly and violently
Orabloc® is an amide local anesthetic containing a vasoconstrictor indicated for local, infiltrative or conductive anesthesia in both simple and complex dental procedures. Orabloc is available in two epinephrine formulations: 1:200,000 - commonly used for routine procedures and 1:100,000 - when pronounced homeostasis or improved visualization of the surgical field is required ...
Florida Dental Anesthesia specializes in dental sedation and sedation dentistry in Palm Beach, Broward and Miami-Dade. Our dental sedation services are comfortable, convenient and most importantly, safe. Florida Dental Anesthesia strives to provide the utmost in patient safety and satisfaction and ensure the highest levels of professionalism safety throughout all dental sedation procedures. If you are searching for a dental sedation expert in the Palm Beach, Broward or Miami-Dade areas, feel free to fill out our contact form and we will have someone contact you. ...
The incidence of missing wisdom teeth was significantly higher in the group that had received dental anesthesia; statistical evidence suggests that this did not happen by chance alone. We hope our findings stimulate research using larger sample sizes and longer periods of observation to confirm our findings and help better understand how wisdom teeth can be stopped from developing," Silvestri continued. "Dentists have been giving local anesthesia to children for nearly 100 years and may have been preventing wisdom teeth from forming without even knowing it. Our findings give hope that a procedure preventing third molar growth can be developed ...
Find out more about dental anesthesia and dental sedation that may be required for a dental procedure. Find more on procedures, risks, and anesthesia types here.
At the Dental Anesthesia Clinic of Montreal, we are equipped and trained to perform dental surgery, including wisdom tooth extraction.
Florida Dental Anesthesia Services would love to hear from you. Please take a moment and share your questions or comments using the form below ...
Study procedures: This study will involve recruiting patients who are scheduled to undergo surgery that requires a regional nerve block via local anesthetic delivery through a perineural catheter. We wish to compare the CON and CTN catheterization methods for delivering local anesthetic during common regional blocks. One hundred patients will be recruited to assess the usefulness of the CON method in delivering local anesthetic. Patients in the study group will receive a continuous infusion of local anesthetic through a CON catheter. Patients in the control group will receive continuous local anesthetic through a CTN catheter. To make data collection easier, we will perform assessments at several locations in the Edmonton zone; anesthesiologists at each location will be asked to participate in performing the blocks and record their assessment of the two catheterization methods.. On the day of surgery, patients will be taken to the regional block area, where they will be positioned appropriately ...
a Cochrane review concluded that BIS within 40 to 60 may improve anaesthetic delivery and postoperative recovery from relatively deep anaesthesia, and more important that BIS-guided anaesthesia significantly reduces the incidence of intraoperative recall in surgical patients with high risk of awareness (ex. TIVA) [Punjasawadwong et al. Cochrane Database Syst Rev. 4: CD003843, 2007]. The largest study in Cochrane was Myles et al. (2463 patients), the second-largest was only 268 patients. Cochrane did not review Avidan (see below), which was published later.. Myles et al. conducted a randomized, double blind trial of 2463 "high risk" patients (caesarean section, high-risk cardiac surgery [EF ,30%, cardiac index ,2·1 L/min per m2, severe aortic stenosis, pulmonary hypertension, or undergoing off-pump coronary artery bypass graft surgery], acute trauma with hypovolaemia, rigid bronchoscopy, significant impairment of cardiovascular status and expected intraoperative hypotension requiring treatment, ...
Sedation dentistry with conscious sedation or Twilight anesthesia for patients needing more than nitrous oxide. Spring TX Dentist 281-547-0839
Oral Premedication Used mostly on young children, oral premedication helps reduce apprehension by prescription of anti anxiety and sedative drugs. Prescribed medication is to be taken orally the night before or several hours before the appointment as directed by the provider. Local anesthesia is then delivered upon arrival to the appointment to eliminate any discomfort…
CEUs: 3 Speaker: Sherri Meyers Join your colleagues to use discussion, problem-solving, and sharing of best practices to enhance radiographic techniques and the quality of your radiographic/digital images and to ensure diagnostic films and client safety. Participants will self-identify concerns or areas where improvement is desired and cover a variety of topics designed to meet ...
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Your dentist could use a technique called lingual infiltration w/ the local anes. called Articaine. Usually works on my patients, or one of the alternative sites for anesthesia. Most herbal medicines do not work for tooth pain unless the nerve is exposed. If it is only decay, get the decay out and place a bonded filling or crown. If the nerve is involved, root canal or ext. It appears that many here are against root canals, but they are a viable treatment if done well. If a person continues to have problems then extract it and put in an implant ...
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Dr. Ed Suh shows how to give a long buccal injection with buffered anesthetic using the Anutra Local Anesthetic Delivery System.. ...
Dental Health Care Providers (DCPs) traditionally use finger retraction or mirror retraction when delivering local anesthesia 1-3. Existing dental anesthesia curriculums and educational programs have not emphasized techniques other than using the finger for retraction of mucosa 4-7. Literature presents cases of needlestick injuries (NSIs) when the finger is used to retract mucosa to deliver anesthesia 8, 9. Innovations towards dental anesthesia delivery have progressed throughout the years 1,4,10-13. In addition, various instruments exist both in clinical practice and on the market to aid in retraction (cheek retractor, tongue depressor, etc.) 1,14-16.. In 2010, a device was approved for purchase in the United States for use during dental anesthesia delivery (Figure 1). This device is a cordless, rechargeable, handheld system that delivers pulsed micro-oscillations to the injection site. The disposable retraction tips consisting of two rubber prongs with an illuminating LED light appropriate for ...
This summary is based on the article published in the Australian Journal of Endodontics titled: Efficacy and safety of articaine versus lidocaine for irreversible pulpitis treatment: A systematic review and meta-analysis of randomised controlled trials (April 2016). Naichuan Su, PhD; Chunjie Li, PhD; Hang Wang, PhD; Jiefei Shen, PhD; Wenjia Liu, PhD; and Liang Kou, MD. Read and Download the full-text version of the article courtesy of Wiley Publishing. Context. Irreversible pulpitis (IP), which is a severe damage to the pulp via bacteria in the vital dental pulp, would cause necrosis or death to pulp tissues, and thus leads to very intolerable severe spontaneous pain and forces patients to seek immediate treatment (1). However, pain is a common phenomenon in dental treatments, so the management of pain and anxiety in dental treatment is associated with patients trust in their dentists (2). More than half of Americans avoid dental treatments because of fear of pain (3). Pain caused by dental ...
When you tell anyone in healthcare that "sedation" to the point of coma is given in dentists and oral surgeons offices every day, without a separate anesthesia professional present to give the medications and monitor the patient, the response often is disbelief.. "But they cant do that," Ive been told more than once.. Yes, they can. Physicians are NOT allowed to do a procedure and provide sedation or general anesthesia at the same time - whether its surgery or a GI endoscopy. But dental practice grew up under a completely different regulatory and legal structure, with state dental boards that are separate from medical boards.. In many states, dentists can give oral "conscious" sedation with nitrous oxide after taking a weekend course, aided only by a dental assistant with a high school diploma and no medical or nursing background. Deaths have occurred when they gave repeated sedative doses to the point that patients stopped breathing either during or after their procedures.. Oral surgeons ...
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Sacramento Periodontists, The Professionals at Capitol Periodontal Group specialize in dentistry procedures such as periodontics, implants, and dental anesthesia in the Roseville, Elk Grove, Folsom, and Sacramento, California areas.
Sacramento Periodontists, The Professionals at Capitol Periodontal Group specialize in dentistry procedures such as periodontics, implants, and dental anesthesia in the Roseville, Elk Grove, Folsom, and Sacramento, California areas.
During pregnancy, the organic systems of a woman are subjected to physiological modifications consequential to hormonal, anatomic and metabolical alterations. The most significant modification in the circulatory system is an increased cardiac output from the first three months of gestation. Women with heart disease may present with severe complications during the gestational period, because of inappropriate adaptation of her body to this hemodynamic overload, even those patients who are thought to have an appropriate functional capacity during early pregnancy. There are scant studies in the literature on the effects of local anesthetics, with and without vasoconstrictor, used in dental procedures on the cardiovascular variables of pregnant women with valvar disease, as well as on their concepti. Driven by this shortage, we decided to have this subject studied, by assessing and analyzing cardiotocographic parameters, such as fetal heart rate (FHR), fetal motility(FM) and uterine contractions ...
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Dr. Hector Villa Jr., M.D. received his medical degree from Louisiana State University School of Medicine in 1989 and completed a 3-year residency in Anesthesia at the University of South Florida, where he received 12 months of advanced training in Pediatric Anesthesia. At graduation he was the recipient of the Dripps Award for outstanding resident. He was certified by the American Board of Anesthesiology in 1994.. Dr. Hector Vila is nationally renowned for his work to improve the quality of care in ambulatory and office based anesthesia. He served as chair of the South Carolina Medical Association Taskforce for Office Surgery Guidelines. He was lead author of the study, "A Comparative Outcomes Analysis of Procedures Performed in Physician Offices and Ambulatory Surgery Centers". Abstracts of this study received international awards and attracted national media attention. He was quoted in US News and World Report, CNN, Good Morning America, and numerous other media. He is considered an expert in ...
Alternative methods for dental anesthesia that have had some success and avoid the possibility of lingual nerve damage including Stabident, hypnosis, electronic anesthesia and Comfordent
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April 21, 2016 -- California lawmakers have approved a bill to increase oversight of pediatric sedation during dental procedures after a 6-year-old boy died while under general anesthesia for an extraction in 2015.. The bill, AB 2235, to be known as Calebs Law, would tighten requirements for dentist supervision of sedated patients and also require dentists to inform parents of an increased risk when general anesthesia is used. In addition, the bill would require the Dental Board of California to investigate state laws on sedation and issue public reports on the deaths and injuries of children from dental anesthesia. Complaint. The measure is in response to a March 2015 extraction procedure by Michael J. Doucet, DDS, an oral surgeon in Albany, CA, during which 6-year-old Caleb Sears died. The boys parents claimed that there were no personnel trained to handle the situation, nor was there sufficient monitoring equipment for emergencies during the treatment.. The dental board filed a complaint on ...
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TY - JOUR. T1 - Visual acuity and pupillary reactions after peribulbar anaesthesia. AU - Talks, S.J.. AU - Chong, N.H.. AU - Gibson, J M. AU - Francis, I.R.. PY - 1994. Y1 - 1994. N2 - The effect of peribulbar anaesthesia on optic nerve function in 20 patients, before and after cataract surgery, was measured. All the patients had decreased visual acuity. Five (25%) had no perception of light. Seventeen (85%) developed a relative afferent pupil defect (RAPD). No patients saw the operating instruments. Seven (35%) had improved visual acuity immediately postoperatively. Patients should be warned that they may lose vision completely on being given a peribulbar anaesthetic; however their vision will improve, but not necessarily immediately, postoperatively. Examination for an RAPD is a good method of providing reassurance that the operating instruments will not be seen.. AB - The effect of peribulbar anaesthesia on optic nerve function in 20 patients, before and after cataract surgery, was measured. ...
If youre in need of a simple extraction/surgical extraction, or even a general wisdom tooth extraction, we can help. Book a consultation w/ our Belvidere, IL office.
PURPOSE The purpose of this study was to determine if the 3M Dental Electronic Anesthesia System 8670 would decrease patients pain/discomfort levels during scaling and root planing procedures. METHODS Forty-nine patients possessing hypersensitive teeth and/or 4-6 mm periodontal pockets requiring scaling and root planing were selected as subjects. Patients received treatment using an inactive and then an active stimulator in paired quadrants. The patients scored their pain/discomfort levels after each procedure. They were contacted by telephone 1-2 days following treatment to determine if they experienced any symptoms or discomfort following electronic dental anesthesia. RESULTS The overall results for the assessment of pain/discomfort indicated that treatment using the active stimulator resulted in significantly lower pain scores for the total patient population. CONCLUSIONS This study found the 3M Dental Electronic Anesthesia System 8670 to be effective for controlling pain during the dental
Andover, MA sedation dentistry with Andover Dental Care - Phone (866) 574-1910 for an experienced Andover sedation dentist in the Andover, North Andover, Methuen, Lawrence, Tewksbury and Essex County area with Charles McQuade, D.M.D. Ask how you can combine cosmetic dentistry with sedation for the smile youve always wanted. We also offer the local Andover area General Dentistry, Dental Anesthesia, Help With Dental Anxiety, Periodontitis, Implant Dentures and Endodontics.
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At SleepyDentistry.net youll find a reputable dental anesthesia and dental sedation provider that delivers safe and efficient relief to valued clients living in or near Cross Plains, IN. Our licensed dentist anesthesiologist is well trained and equipped and specializes on pain control and patient management. From general anesthesia, tropical anesthesia, local anesthesia and other types of dental anesthesia, our certified and experienced anesthesiologist provide various anesthesia requirements for dental patients. We also offer portable in-office moderate dental sedation to provide a more comfortable dental experience. You may also want a moderate I.V. sedation instead for a more relaxed state during dental procedures especially for dental surgeries. If you have a post traumatic stress disorder, special medical conditions such as autism or mental illness, TMJ discomfort or suffer from anxiety, dental sedation is the best option. Our outstanding service is open to all 47017 patients as well as ...
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When 60 g of lidocaine and prilocaine cream, 2.5%/2.5% was applied over 400 cm2 for 24 hours, peak blood levels of lidocaine are approximately 1/20 the systemic toxic level. Likewise, the maximum prilocaine level is about 1/36 the toxic level. In a pharmacokinetic study, lidocaine and prilocaine cream, 2.5%/2.5% was applied to penile skin in 20 adult male patients in doses ranging from 0.5 g to 3.3 g for 15 minutes. Plasma concentrations of lidocaine and prilocaine following lidocaine and prilocaine cream, 2.5%/2.5% application in this study were consistently low (2.5-16 ng/mL for lidocaine and 2.5-7 ng/mL for prilocaine). The application of lidocaine and prilocaine cream, 2.5%/2.5% to broken or inflamed skin, or to 2,000 cm2 or more of skin where more of both anesthetics are absorbed, could result in higher plasma levels that could, in susceptible individuals, produce a systemic pharmacologic response.. The absorption of lidocaine and prilocaine cream, 2.5%/2.5% applied to genital mucous ...
Lidocaine and prilocaine cream application in adults prior to IV cannulation or venipuncture was studied in 200 patients in four clinical studies in Europe. Application for at least 1 hour provided significantly more dermal analgesia than placebo cream or ethyl chloride. Lidocaine and prilocaine cream was comparable to subcutaneous lidocaine, but was less efficacious than intradermal lidocaine. Most patients found lidocaine and prilocaine cream treatment preferable to lidocaine infiltration or ethyl chloride spray.. Lidocaine and prilocaine cream was compared with 0.5% lidocaine infiltration prior to skin graft harvesting in one open label study in 80 adult patients in England. Application of lidocaine and prilocaine cream for 2 to 5 hours provided dermal analgesia comparable to lidocaine infiltration.. Lidocaine and prilocaine cream application in children was studied in seven non-US studies (320 patients) and one US study (100 patients). In controlled studies, application of lidocaine and ...
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... carticaine MeSH D03.383.903.370 --- ketotifen MeSH D03.383.903.440 --- morantel MeSH D03.383.903.580 --- pizotyline MeSH ...
... carticaine MeSH D02.886.778.370 --- ketotifen MeSH D02.886.778.440 --- morantel MeSH D02.886.778.580 --- pizotyline MeSH ...
The primary use for procaine is as an anaesthetic. Procaine is used less frequently today, since more effective (and hypoallergenic) alternatives such as lidocaine (Xylocaine) exist. Like other local anesthetics (such as mepivacaine, and prilocaine), procaine is a vasodilator, thus is often coadministered with epinephrine for the purpose of vasoconstriction. Vasoconstriction helps to reduce bleeding, increases the duration and quality of anesthesia, prevents the drug from reaching systemic circulation in large amounts, and overall reduces the amount of anesthetic required.[7] Unlike cocaine, a vasoconstrictor, procaine does not have the euphoric and addictive qualities that put it at risk for abuse. Procaine, an ester anesthetic, is metabolized in the plasma by the enzyme pseudocholinesterase through hydrolysis into para-amino benzoic acid (PABA), which is then excreted by the kidneys into the urine. A 1% procaine injection has been recommended for the treatment of extravasation complications ...
In Peru, the ancient Incas are believed to have used the leaves of the coca plant as a local anaesthetic in addition to its stimulant properties.[59] It was also used for slave payment and is thought to play a role in the subsequent destruction of Incas culture when Spaniards realized the effects of chewing the coca leaves and took advantage of it.[59] Cocaine was first used as a local anesthetic in 1884. The search for a less toxic and less addictive substitute led to the development of the aminoester local anesthetics stovaine in 1903 and procaine in 1904. Since then, several synthetic local anesthetic drugs have been developed and put into clinical use, notably lidocaine in 1943, bupivacaine in 1957, and prilocaine in 1959. The invention of clinical use of local anaesthesia is credited to the Vienna School which included Sigmund Freud (1856-1939), Carl Koller (1857-1944) and Leopold Konigstein (1850-1942). They introduced local anaesthesia, using cocaine, through 'self-experimation' on their ...
Adverse drug reactions (ADRs) are rare when it is administered correctly. Most ADRs relate to administration technique (resulting in systemic exposure) or pharmacological effects of anesthesia, however allergic reactions can rarely occur. Systemic exposure to excessive quantities of ropivacaine mainly result in central nervous system (CNS) and cardiovascular effects - CNS effects usually occur at lower blood plasma concentrations and additional cardiovascular effects present at higher concentrations, though cardiovascular collapse may also occur with low concentrations. CNS effects may include CNS excitation (nervousness, tingling around the mouth, tinnitus, tremor, dizziness, blurred vision, seizures followed by depression (drowsiness, loss of consciousness), respiratory depression and apnea). Cardiovascular effects include hypotension, bradycardia, arrhythmias, and/or cardiac arrest - some of which may be due to hypoxemia secondary to respiratory depression.[2] ...
... was developed to meet the need for a short-acting spinal anaesthetic that is reliable and has a favourable safety profile to support the growing need for day-case surgery. Licensed in Europe for surgical procedures up to 40 minutes, chloroprocaine is an ester-type local anaesthetic with the shortest duration of action of all the established local anaesthetics. It has a significantly shorter duration of action than lidocaine and is significantly less toxic. Chloroprocaine has a motor block lasting for 40 minutes, a rapid onset time of 3-5 minutes (9.6 min ± 7.3 min at 40 mg dose; 7.9 min ± 6.0 min at 50 mg dose) and a time to ambulation of 90 minutes without complications, especially lacking transient neurologic symptomatology.. These data are based upon a retrospective review of 672 patients suitable for spinal anaesthesia in surgical procedures less than 60 minutes' duration using 30-40 mg chloroprocaine. The results showed good surgical anaesthesia, a fast onset time, and ...
Class Ib antiarrhythmic agents are sodium channel blockers. They have fast onset and offset kinetics, meaning that they have little or no effect at slower heart rates, and more effects at faster heart rates. Class Ib agents shorten the action potential duration and reduce refractoriness. These agents will decrease Vmax in partially depolarized cells with fast response action potentials. They either do not change the action potential duration, or they may decrease the action potential duration. Class Ib drugs tend to be more specific for voltage gated Na channels than Ia. Lidocaine in particular is highly frequency dependent, in that it has more activity with increasing heart rates. This is because lidocaine selectively blocks Na channels in their open and inactive states and has little binding capability in the resting state. Class Ib agents are indicated for the treatment of ventricular tachycardia and symptomatic premature ventricular beats, and prevention of ventricular fibrillation. Class Ib ...
InChI=1S/C20H29N3O2/c1-4-7-14-25-19-15-17(16-10-8-9-11-18(16)22-19)20(24)21-12-13-23(5-2)6-3/h8-11,15H,4-7,12-14H2,1-3H3,(H,21,24) ...
Articaine • Bupivacaine # /Levobupivacaine/Ropivacaine • Carticaine • Cinchocaine • Etidocaine • Lidocaine # • Mepivacaine • ...
... carticaine, chloroprocaine hydrochloride, cocaethylene, cocaine, cyclomethycaine, dibucaine hydrochloride, dimethisoquin, ...
Carticaine. Epinephryl borate. Anesthetics, Local. Anesthetics. Central Nervous System Depressants. Physiological Effects of ...
Carticaine. Anesthetics. Epinephrine. Racepinephrine. Epinephryl borate. Anesthetics, Local. Central Nervous System Depressants ...
Carticaine. Group. アルチカイン塩酸塩 belongs to this group or family:. *ATC N01B: Anesthetics, local ...
99.6% Articaine Hydrochloride Carticaine HCL Dental Local Anesthetic API CAS 23964-57-0 Attention: China 14 years old ... 99.6% Articaine Hydrochloride Carticaine HCL Dental Local Anesthetic CAS 23964-57-0 ... 99.6% Articaine Hydrochloride Carticaine HCL Dental Local Anesthetic CAS 23964-57-0 ...
Articaine was originally synthesized as Carticaine by H.. Advances in local anaesthesia: a paediatric overview ...
Carticaine (Articaine)IBA 01/01/2013 - "The results suggest that articaine is not toxic to the nervous structure and further ...
This drug was originally referred to as "carticaine" until 1984. In 1983 it was brought into the North American market, to ... Carticaine(articaine) PubChem page Orabloc Septodont Structure Permanent Nerve Damage from Inferior Alveolar Nerve Blocks: An ...
2-Thiophenecarboxylicacid, 4-methyl-3-[2-(propylamino)propionamido]-, methyl ester (8CI);Carticaine; ...
Aktuelle API Auditberichte • GMP-Audits der Herstelung pharmazeutischer Ausgangs- und Wirkstoffe nach ICH Q7 / EU GMP Guide Part II • Diapharm
Carticaine(Anesthetic (local).). *Carubicin(Antineoplastic.). *Carumonam(Antibacterial.). *Carvacrol(Has been used as anti- ...
... carticaine, centbucridine, cepacaine, cetacaine, chloroprocaine, cocaethylene, cocaine, pseudococaine, cyclomethycaine, ...
... carticaine, chloroprocaine, cocaethylene, cocaine, cyclomethycaine, dibucaine, dimethysoquin, dimethocaine, diperodon, ...
... carticaine, chloroprocaine hydrochloride, cocaethylene, cocaine, cyclomethycaine, dibucaine hydrochloride, dimethisoquin, ...
... carticaine MeSH D03.383.903.370 --- ketotifen MeSH D03.383.903.440 --- morantel MeSH D03.383.903.580 --- pizotyline MeSH ...
... carticaine MeSH D02.886.778.370 --- ketotifen MeSH D02.886.778.440 --- morantel MeSH D02.886.778.580 --- pizotyline MeSH ...
Delmaghani, S., Defourny, J., Aghaie, A., Beurg, M., Dulon, D., Thelen, N., Perfettini, I., Zelles, T., Aller, M., Meyer, A., Emptoz, A., Giraudet, F., Leibovici, M., Dartevelle, S., Soubigou, G., Thiry, M., Vizi, E. S., Safieddine, S., Hardelin, J. P., Avan, P. & 1 others, Petit, C., Nov 5 2015, In : Cell. 163, 4, p. 894-906 13 p.. Research output: Contribution to journal › Article ...
Smolen, J. S., Schoels, M. M., Nishimoto, N., Breedveld, F. C., Burmester, G. R., Dougados, M., Emery, P., Ferraccioli, G., Gabay, C., Gibofsky, A., Gomez-Reino, J. J., Jones, G., Kvien, T. K., Murakami, M., Betteridge, N., Bingham, C. O., Bykerk, V., Choy, E. H., Combe, B., Cutolo, M. & 15 others, Graninger, W., Lanas, A., Martin-Mola, E., Montecucco, C., Ostergaard, M., Pavelka, K., Rubbert-Roth, A., Sattar, N., Scholte-Voshaar, M., Tanaka, Y., Trauner, M., Valentini, G., Winthrop, K., De Wit, M. & Van Der Heijde, D., Apr 2013, In : Annals of the Rheumatic Diseases. 72, 4, p. 482-492 11 p.. Research output: Contribution to journal › Article ...
... carticaine, chloroprocaine hydrochloride, cocaethylene, cocaine, cyclomethycaine, dibucaine hydrochloride, dimethisoquin, ...
... carticaine, chloroprocaine hydrochloride, cocaethylene, cocaine, cyclomethycaine, dibucaine hydrochloride, dimethisoquin, ...
... carticaine, chloroprocaine hydrochloride, cocaethylene, cocaine, cyclomethycaine, dibucaine hydrochloride, dimethisoquin, ...
... carticaine, centbucridine, cepacaine, cetacaine, chloroprocaine, cocaethylene, cocaine, pseudococaine, cyclomethycaine, ...
... carticaine, chloroprocaine hydrochloride, cocaethylene, cocaine, cyclomethycaine, dibucaine hydrochloride, dimethisoquin, ...
The primary use for procaine is as an anaesthetic. Procaine is used less frequently today, since more effective (and hypoallergenic) alternatives such as lidocaine (Xylocaine) exist. Like other local anesthetics (such as mepivacaine, and prilocaine), procaine is a vasodilator, thus is often coadministered with epinephrine for the purpose of vasoconstriction. Vasoconstriction helps to reduce bleeding, increases the duration and quality of anesthesia, prevents the drug from reaching systemic circulation in large amounts, and overall reduces the amount of anesthetic required.[7] Unlike cocaine, a vasoconstrictor, procaine does not have the euphoric and addictive qualities that put it at risk for abuse. Procaine, an ester anesthetic, is metabolized in the plasma by the enzyme pseudocholinesterase through hydrolysis into para-amino benzoic acid (PABA), which is then excreted by the kidneys into the urine. A 1% procaine injection has been recommended for the treatment of extravasation complications ...

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