Carotid Sinus: The dilated portion of the common carotid artery at its bifurcation into external and internal carotids. It contains baroreceptors which, when stimulated, cause slowing of the heart, vasodilatation, and a fall in blood pressure.Carotid Arteries: Either of the two principal arteries on both sides of the neck that supply blood to the head and neck; each divides into two branches, the internal carotid artery and the external carotid artery.Pressoreceptors: Receptors in the vascular system, particularly the aorta and carotid sinus, which are sensitive to stretch of the vessel walls.Carotid Stenosis: Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3)Carotid Artery Diseases: Pathological conditions involving the CAROTID ARTERIES, including the common, internal, and external carotid arteries. ATHEROSCLEROSIS and TRAUMA are relatively frequent causes of carotid artery pathology.Carotid Body: A small cluster of chemoreceptive and supporting cells located near the bifurcation of the internal carotid artery. The carotid body, which is richly supplied with fenestrated capillaries, senses the pH, carbon dioxide, and oxygen concentrations in the blood and plays a crucial role in their homeostatic control.Syncope: A transient loss of consciousness and postural tone caused by diminished blood flow to the brain (i.e., BRAIN ISCHEMIA). Presyncope refers to the sensation of lightheadedness and loss of strength that precedes a syncopal event or accompanies an incomplete syncope. (From Adams et al., Principles of Neurology, 6th ed, pp367-9)Endarterectomy, Carotid: The excision of the thickened, atheromatous tunica intima of a carotid artery.Carotid Artery, Internal: Branch of the common carotid artery which supplies the anterior part of the brain, the eye and its appendages, the forehead and nose.Chemoreceptor Cells: Cells specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptor cells may monitor external stimuli, as in TASTE and OLFACTION, or internal stimuli, such as the concentrations of OXYGEN and CARBON DIOXIDE in the blood.Massage: The systematic and methodical manipulations of body tissues best performed with the hands for the purpose of affecting the nervous and muscular systems and the general circulation.Carotid Artery, Common: The two principal arteries supplying the structures of the head and neck. They ascend in the neck, one on each side, and at the level of the upper border of the thyroid cartilage, each divides into two branches, the external (CAROTID ARTERY, EXTERNAL) and internal (CAROTID ARTERY, INTERNAL) carotid arteries.Cranial Sinuses: Large endothelium-lined venous channels situated between the two layers of DURA MATER, the endosteal and the meningeal layers. They are devoid of valves and are parts of the venous system of dura mater. Major cranial sinuses include a postero-superior group (such as superior sagittal, inferior sagittal, straight, transverse, and occipital) and an antero-inferior group (such as cavernous, petrosal, and basilar plexus).Maxillary Sinus: The air space located in the body of the MAXILLARY BONE near each cheek. Each maxillary sinus communicates with the middle passage (meatus) of the NASAL CAVITY on the same side.Sinus of Valsalva: The dilatation of the aortic wall behind each of the cusps of the aortic valve.Reflex: An involuntary movement or exercise of function in a part, excited in response to a stimulus applied to the periphery and transmitted to the brain or spinal cord.Cavernous Sinus: An irregularly shaped venous space in the dura mater at either side of the sphenoid bone.Paranasal Sinuses: Air-filled spaces located within the bones around the NASAL CAVITY. They are extensions of the nasal cavity and lined by the ciliated NASAL MUCOSA. Each sinus is named for the cranial bone in which it is located, such as the ETHMOID SINUS; the FRONTAL SINUS; the MAXILLARY SINUS; and the SPHENOID SINUS.Carotid Artery, External: Branch of the common carotid artery which supplies the exterior of the head, the face, and the greater part of the neck.Blood Pressure: PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.Denervation: The resection or removal of the nerve to an organ or part. (Dorland, 28th ed)Baroreflex: A response by the BARORECEPTORS to increased BLOOD PRESSURE. Increased pressure stretches BLOOD VESSELS which activates the baroreceptors in the vessel walls. The net response of the CENTRAL NERVOUS SYSTEM is a reduction of central sympathetic outflow. This reduces blood pressure both by decreasing peripheral VASCULAR RESISTANCE and by lowering CARDIAC OUTPUT. Because the baroreceptors are tonically active, the baroreflex can compensate rapidly for both increases and decreases in blood pressure.Frontal Sinus: One of the paired, but seldom symmetrical, air spaces located between the inner and outer compact layers of the FRONTAL BONE in the forehead.Dogs: The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)Sphenoid Sinus: One of the paired air spaces located in the body of the SPHENOID BONE behind the ETHMOID BONE in the middle of the skull. Sphenoid sinus communicates with the posterosuperior part of NASAL CAVITY on the same side.Paranasal Sinus Diseases: Diseases affecting or involving the PARANASAL SINUSES and generally manifesting as inflammation, abscesses, cysts, or tumors.Tilt-Table Test: A standard and widely accepted diagnostic test used to identify patients who have a vasodepressive and/or cardioinhibitory response as a cause of syncope. (From Braunwald, Heart Disease, 7th ed)Vagotomy: The interruption or removal of any part of the vagus (10th cranial) nerve. Vagotomy may be performed for research or for therapeutic purposes.Sick Sinus Syndrome: A condition caused by dysfunctions related to the SINOATRIAL NODE including impulse generation (CARDIAC SINUS ARREST) and impulse conduction (SINOATRIAL EXIT BLOCK). It is characterized by persistent BRADYCARDIA, chronic ATRIAL FIBRILLATION, and failure to resume sinus rhythm following CARDIOVERSION. This syndrome can be congenital or acquired, particularly after surgical correction for heart defects.Coronary Sinus: A short vein that collects about two thirds of the venous blood from the MYOCARDIUM and drains into the RIGHT ATRIUM. Coronary sinus, normally located between the LEFT ATRIUM and LEFT VENTRICLE on the posterior surface of the heart, can serve as an anatomical reference for cardiac procedures.Syncope, Vasovagal: Loss of consciousness due to a reduction in blood pressure that is associated with an increase in vagal tone and peripheral vasodilation.Vagus Nerve: The 10th cranial nerve. The vagus is a mixed nerve which contains somatic afferents (from skin in back of the ear and the external auditory meatus), visceral afferents (from the pharynx, larynx, thorax, and abdomen), parasympathetic efferents (to the thorax and abdomen), and efferents to striated muscle (of the larynx and pharynx).Heart Rate: The number of times the HEART VENTRICLES contract per unit of time, usually per minute.Carotid Artery Thrombosis: Blood clot formation in any part of the CAROTID ARTERIES. This may produce CAROTID STENOSIS or occlusion of the vessel, leading to TRANSIENT ISCHEMIC ATTACK; CEREBRAL INFARCTION; or AMAUROSIS FUGAX.Sinus Thrombosis, Intracranial: Formation or presence of a blood clot (THROMBUS) in the CRANIAL SINUSES, large endothelium-lined venous channels situated within the SKULL. Intracranial sinuses, also called cranial venous sinuses, include the superior sagittal, cavernous, lateral, petrous sinuses, and many others. Cranial sinus thrombosis can lead to severe HEADACHE; SEIZURE; and other neurological defects.Glossopharyngeal Nerve: The 9th cranial nerve. The glossopharyngeal nerve is a mixed motor and sensory nerve; it conveys somatic and autonomic efferents as well as general, special, and visceral afferents. Among the connections are motor fibers to the stylopharyngeus muscle, parasympathetic fibers to the parotid glands, general and taste afferents from the posterior third of the tongue, the nasopharynx, and the palate, and afferents from baroreceptors and CHEMORECEPTOR CELLS of the carotid sinus.Carotid Artery Injuries: Damages to the CAROTID ARTERIES caused either by blunt force or penetrating trauma, such as CRANIOCEREBRAL TRAUMA; THORACIC INJURIES; and NECK INJURIES. Damaged carotid arteries can lead to CAROTID ARTERY THROMBOSIS; CAROTID-CAVERNOUS SINUS FISTULA; pseudoaneurysm formation; and INTERNAL CAROTID ARTERY DISSECTION. (From Am J Forensic Med Pathol 1997, 18:251; J Trauma 1994, 37:473)Sodium Cyanide: A highly poisonous compound that is an inhibitor of many metabolic processes and is used as a test reagent for the function of chemoreceptors. It is also used in many industrial processes.Ethmoid Sinus: The numerous (6-12) small thin-walled spaces or air cells in the ETHMOID BONE located between the eyes. These air cells form an ethmoidal labyrinth.Cats: The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)Carotid Body Tumor: Benign paraganglioma at the bifurcation of the COMMON CAROTID ARTERIES. It can encroach on the parapharyngeal space and produce dysphagia, pain, and cranial nerve palsies.Bradycardia: Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.Carotid Intima-Media Thickness: A measurement of the thickness of the carotid artery walls. It is measured by B-mode ULTRASONOGRAPHY and is used as a surrogate marker for ATHEROSCLEROSIS.Respiration: The act of breathing with the LUNGS, consisting of INHALATION, or the taking into the lungs of the ambient air, and of EXHALATION, or the expelling of the modified air which contains more CARBON DIOXIDE than the air taken in (Blakiston's Gould Medical Dictionary, 4th ed.). This does not include tissue respiration (= OXYGEN CONSUMPTION) or cell respiration (= CELL RESPIRATION).Neurons, Efferent: Neurons which send impulses peripherally to activate muscles or secretory cells.Heart Massage: Rhythmic compression of the heart by pressure applied manually over the sternum (closed heart massage) or directly to the heart through an opening in the chest wall (open heart massage). It is done to reinstate and maintain circulation. (Dorland, 28th ed)Sympathetic Nervous System: The thoracolumbar division of the autonomic nervous system. Sympathetic preganglionic fibers originate in neurons of the intermediolateral column of the spinal cord and project to the paravertebral and prevertebral ganglia, which in turn project to target organs. The sympathetic nervous system mediates the body's response to stressful situations, i.e., the fight or flight reactions. It often acts reciprocally to the parasympathetic system.Autonomic Denervation: The removal or interruption of some part of the autonomic nervous system for therapeutic or research purposes.Vascular Resistance: The force that opposes the flow of BLOOD through a vascular bed. It is equal to the difference in BLOOD PRESSURE across the vascular bed divided by the CARDIAC OUTPUT.Phrenic Nerve: The motor nerve of the diaphragm. The phrenic nerve fibers originate in the cervical spinal column (mostly C4) and travel through the cervical plexus to the diaphragm.Paranasal Sinus Neoplasms: Tumors or cancer of the PARANASAL SINUSES.Fludrocortisone: A synthetic mineralocorticoid with anti-inflammatory activity.Tunica Intima: The innermost layer of an artery or vein, made up of one layer of endothelial cells and supported by an internal elastic lamina.Endarterectomy: Surgical excision, performed under general anesthesia, of the atheromatous tunica intima of an artery. When reconstruction of an artery is performed as an endovascular procedure through a catheter, it is called ATHERECTOMY.Tunica Media: The middle layer of blood vessel walls, composed principally of thin, cylindrical, smooth muscle cells and elastic tissue. It accounts for the bulk of the wall of most arteries. The smooth muscle cells are arranged in circular layers around the vessel, and the thickness of the coat varies with the size of the vessel.Reflex, Abnormal: An abnormal response to a stimulus applied to the sensory components of the nervous system. This may take the form of increased, decreased, or absent reflexes.Chloralose: A derivative of CHLORAL HYDRATE that was used as a sedative but has been replaced by safer and more effective drugs. Its most common use is as a general anesthetic in animal experiments.Tachycardia, Sinus: Simple rapid heartbeats caused by rapid discharge of impulses from the SINOATRIAL NODE, usually between 100 and 180 beats/min in adults. It is characterized by a gradual onset and termination. Sinus tachycardia is common in infants, young children, and adults during strenuous physical activities.Heart Sounds: The sounds heard over the cardiac region produced by the functioning of the heart. There are four distinct sounds: the first occurs at the beginning of SYSTOLE and is heard as a "lubb" sound; the second is produced by the closing of the AORTIC VALVE and PULMONARY VALVE and is heard as a "dupp" sound; the third is produced by vibrations of the ventricular walls when suddenly distended by the rush of blood from the HEART ATRIA; and the fourth is produced by atrial contraction and ventricular filling.Accidental Falls: Falls due to slipping or tripping which may result in injury.Pacemaker, Artificial: A device designed to stimulate, by electric impulses, contraction of the heart muscles. It may be temporary (external) or permanent (internal or internal-external).Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.Maxillary Sinus Neoplasms: Tumors or cancer of the MAXILLARY SINUS. They represent the majority of paranasal neoplasms.Carotid Artery, Internal, Dissection: The splitting of the vessel wall in one or both (left and right) internal carotid arteries (CAROTID ARTERY, INTERNAL). Interstitial hemorrhage into the media of the vessel wall can lead to occlusion of the internal carotid artery and aneurysm formation.Dizziness: An imprecise term which may refer to a sense of spatial disorientation, motion of the environment, or lightheadedness.Sympathectomy: The removal or interruption of some part of the sympathetic nervous system for therapeutic or research purposes.Cross Circulation: The circulation in a portion of the body of one individual of blood supplied from another individual.Electrocardiography: Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.VeratrineSyndrome: A characteristic symptom complex.Pilonidal Sinus: A hair-containing cyst or sinus, occurring chiefly in the coccygeal region.Neck: The part of a human or animal body connecting the HEAD to the rest of the body.Cerebral Angiography: Radiography of the vascular system of the brain after injection of a contrast medium.Carbon Dioxide: A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.Hemodynamics: The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Anoxia: Relatively complete absence of oxygen in one or more tissues.Electric Stimulation: Use of electric potential or currents to elicit biological responses.Pressure: A type of stress exerted uniformly in all directions. Its measure is the force exerted per unit area. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Transverse Sinuses: The two large endothelium-lined venous channels that begin at the internal occipital protuberance at the back and lower part of the CRANIUM and travels laterally and forward ending in the internal jugular vein (JUGULAR VEINS). One of the transverse sinuses, usually the right one, is the continuation of the SUPERIOR SAGITTAL SINUS. The other transverse sinus is the continuation of the straight sinus.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Efferent Pathways: Nerve structures through which impulses are conducted from a nerve center toward a peripheral site. Such impulses are conducted via efferent neurons (NEURONS, EFFERENT), such as MOTOR NEURONS, autonomic neurons, and hypophyseal neurons.Rabbits: The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.Blood Circulation: The movement of the BLOOD as it is pumped through the CARDIOVASCULAR SYSTEM.Cardiac Pacing, Artificial: Regulation of the rate of contraction of the heart muscles by an artificial pacemaker.Aorta: The main trunk of the systemic arteries.Ultrasonography, Doppler, Duplex: Ultrasonography applying the Doppler effect combined with real-time imaging. The real-time image is created by rapid movement of the ultrasound beam. A powerful advantage of this technique is the ability to estimate the velocity of flow from the Doppler shift frequency.Medulla Oblongata: The lower portion of the BRAIN STEM. It is inferior to the PONS and anterior to the CEREBELLUM. Medulla oblongata serves as a relay station between the brain and the spinal cord, and contains centers for regulating respiratory, vasomotor, cardiac, and reflex activities.Superior Sagittal Sinus: The long large endothelium-lined venous channel on the top outer surface of the brain. It receives blood from a vein in the nasal cavity, runs backwards, and gradually increases in size as blood drains from veins of the brain and the DURA MATER. Near the lower back of the CRANIUM, the superior sagittal sinus deviates to one side (usually the right) and continues on as one of the TRANSVERSE SINUSES.Aorta, Thoracic: The portion of the descending aorta proceeding from the arch of the aorta and extending to the DIAPHRAGM, eventually connecting to the ABDOMINAL AORTA.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Vasomotor System: The neural systems which act on VASCULAR SMOOTH MUSCLE to control blood vessel diameter. The major neural control is through the sympathetic nervous system.Stents: Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.Hypesthesia: Absent or reduced sensitivity to cutaneous stimulation.Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.Unconsciousness: Loss of the ability to maintain awareness of self and environment combined with markedly reduced responsiveness to environmental stimuli. (From Adams et al., Principles of Neurology, 6th ed, pp344-5)Ischemic Attack, Transient: Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)Autonomic Nerve Block: Interruption of sympathetic pathways, by local injection of an anesthetic agent, at any of four levels: peripheral nerve block, sympathetic ganglion block, extradural block, and subarachnoid block.Neurons, Afferent: Neurons which conduct NERVE IMPULSES to the CENTRAL NERVOUS SYSTEM.Cardiac Output: The volume of BLOOD passing through the HEART per unit of time. It is usually expressed as liters (volume) per minute so as not to be confused with STROKE VOLUME (volume per beat).Afferent Pathways: Nerve structures through which impulses are conducted from a peripheral part toward a nerve center.Perfusion: Treatment process involving the injection of fluid into an organ or tissue.Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.Mechanoreceptors: Cells specialized to transduce mechanical stimuli and relay that information centrally in the nervous system. Mechanoreceptor cells include the INNER EAR hair cells, which mediate hearing and balance, and the various somatosensory receptors, often with non-neural accessory structures.Hypotension, Orthostatic: A significant drop in BLOOD PRESSURE after assuming a standing position. Orthostatic hypotension is a finding, and defined as a 20-mm Hg decrease in systolic pressure or a 10-mm Hg decrease in diastolic pressure 3 minutes after the person has risen from supine to standing. Symptoms generally include DIZZINESS, blurred vision, and SYNCOPE.Constriction: The act of constricting.

Reduction in baroreflex cardiovascular responses due to venous infusion in the rabbit. (1/508)

We studied reflex bradycardia and depression of mean arterial blood pressure (MAP) during left aortic nerve (LAN) stimulation before and after volume infusion in the anesthetized rabbit. Step increases in mean right atrial pressure (MRAP) to 10 mm Hg did not result in a significant change in heart rate or MAP. After volume loading, responses to LAN stimulation were not as great and the degree of attenuation was propoetional to the level of increased MRAP. A change in responsiveness was observed after elevation of MRAP by only 1 mm Hg, corresponding to less than a 10% increase in average calculated blood volume. after an increase in MRAP of 10 mm Hg, peak responses were attenuated by 44% (heart rate) and 52% (MAP), and the initial slopes (rate of change) were reduced by 46% (heart rate) and 66% (MAP). Comparison of the responses after infusion with blood and dextran solutions indicated that hemodilution was an unlikely explanation for the attenuation of the reflex responses. Total arterial baroreceptor denervation (ABD) abolished the volume-related attenuation was still present following bilateral aortic nerve section or vagotomy. It thus appears that the carotid sinus responds to changes inblood volume and influences the reflex cardiovascular responses to afferent stimulation of the LAN. On the other hand, cardiopulmonary receptors subserved by vagal afferents do not appear to be involved.  (+info)

Quantification of baroreceptor influence on arterial pressure changes seen in primary angiotension-induced hypertension in dogs. (2/508)

We studied the role of the sino-aortic baroreceptors in the gradual development of hypertension induced by prolonged administration of small amounts of angiotensin II (A II) in intact dogs and dogs with denervated sino-aortic baroreceptors. Short-term 1-hour infusions of A II(1.0-100 ng/kg per min) showed that conscious denervated dogs had twice the pressor sensitivity of intact dogs. Long-term infusions of A II at 5.0 ng/kg per min (2-3 weeks) with continuous 24-hour recordings of arterial pressure showed that intact dogs required 28 hours to reach the same level of pressure attained by denervated dogs during the 1st hour of infusion. At the 28th hour the pressure in both groups was 70% of the maximum value attained by the 7th day of infusion. Both intact and denervated dogs reached nearly the same plateau level of pressure, the magnitude being directly related both the the A II infusion rate and the daily sodium intake. Cardiac output in intact dogs initially decreased after the onset of A II infusion, but by the 5th day of infusion it was 38% above control, whereas blood volume was unchanged. Heart rate returned to normal after a reduction during the 1st day of infusion in intact dogs. Plasma renin activity could not be detected after 24 hours of A II infusion in either intact or denervated dogs. The data indicate that about 35% of the hypertensive effect of A II results from its acute pressor action, and an additional 35% of the gradual increase in arterial pressure is in large measure a result of baroreceptor resetting. We conclude that the final 30% increase in pressure seems to result from increased cardiac output, the cause of which may be decreased vascular compliance. since the blood volume remains unaltered.  (+info)

Hypoxia inhibits baroreflex vagal bradycardia via a central action in anaesthetized rats. (3/508)

It is known that arterial baroreflexes are suppressed in stressful conditions. The present study was designed to determine whether and how hypoxia affects arterial baroreflexes, especially the heart rate component, baroreflex vagal bradycardia. In chloralose-urethane-anaesthetized rats, baroreflex vagal bradycardia was evoked by electrical stimulation of the aortic depressor nerve, and the effect of 15 s inhalation of hypoxic gas (4% O2) was studied. Inhalation of hypoxic gas was found to inhibit baroreflex vagal bradycardia. The inhibition persisted after bilateral transection of the carotid sinus nerve. Cervical vagus nerves were cut bilaterally and their peripheral cut ends were stimulated to provoke vagal bradycardia of peripheral origin so as to determine whether hypoxia could inhibit vagal bradycardia by acting on a peripheral site. In contrast to baroreflex vagal bradycardia, the vagus-induced bradycardia was not affected by hypoxic gas inhalation. It is concluded that baroreflex vagal bradycardia is inhibited by hypoxia and the inhibition is largely mediated by its direct central action.  (+info)

Responses of abdominal vascular capacitance in the anaesthetized dog to changes in carotid sinus pressure. (4/508)

1. The abdominal circulation of anaesthetized dogs was vascularly isolated without opening the abdomen, by cutting or tying all structures immediately above the diaphragm and tying the proximal ends of the hind limbs. The region was perfused at constant flow through the aorta and drained at constant pressure from the inferior vena cava. 2. Vascular resistance responses were expressed as the changes in perfusion pressure and capacitance responses were determined by integrating changes in vena caval outflow. 3. Decreasing the pressure in the isolated carotid sinuses over the whole baroreceptor sensitivity range increased mean perfusion pressure from 91 to 149 mmHg (a 67% increase in resistance) and decreased mean capacitance by 111 ml. (5 ml. kg-1). 4. The range of carotid sinus pressures over which capacitance responses occurred was at a significantly higher level than the corresponding range for resistance responses. 5. Comparison of the reflex responses with the responses to direct stimulation of efferent sympathetic nerves shows that quantitatively similar responses of resistance and capacitance to those induced by a large step decrease in carotid pressure could be produced by stimulating maximally the efferent sympathetic nerves at 5 Hz. These results also suggest that at all levels of carotid sinus pressure there is no difference in the impulse traffic to resistance and capacitance vessels.  (+info)

Carotid sinus hypersensitivity--a modifiable risk factor for fractured neck of femur. (5/508)

BACKGROUND: the potential impact on morbidity, mortality and health care economics makes it important to identify patients at risk of fracture, in particular fractured neck of femur (FNOF). Older patients with carotid sinus hypersensitivity (CSH) are more likely to have unexplained falls and to experience fractures, particularly FNOF. Our objective was to determine the prevalence of CSH in patients with FNOF. DESIGN: case-controlled prospective series. METHODS: consecutive cases were admissions over 65 years with FNOF. Controls were consecutive patients admitted for elective hip surgery, frail elderly people admitted to hospital medical wards and day-hospital patients. All patients had a clinical assessment of cognitive function, physical abilities and history of previous syncope, falls and dizziness, in addition to repeated carotid sinus massage with continuous heart rate and phasic blood pressure measurement. RESULTS: heart rate slowing and fall in systolic blood pressure was greater for patients with FNOF than those admitted for elective hip surgery (P < 0.05 and P < 0.001). CSH was present in 36% of the FNOF group, none of the elective surgery group, 13% of the acutely ill controls and 17% of the outpatients. It was more likely to be present in FNOF patients with a previous history of unexplained falls or an unexplained fall causing the index fracture. The heart rate and systolic blood pressure responses to carotid sinus stimulation were reproducible. CONCLUSION: older patients with an acute neck of femur fracture who do not give a clear history of an accidental fall or who have had previously unexplained falls are likely to have CSH. CSH may be a modifiable risk factor for older patients at risk of hip fracture.  (+info)

New analytic framework for understanding sympathetic baroreflex control of arterial pressure. (6/508)

The sympathetic baroreflex is an important feedback system in stabilization of arterial pressure. This system can be decomposed into the controlling element (mechanoneural arc) and the controlled element (neuromechanical arc). We hypothesized that the intersection of the two operational curves representing their respective functions on an equilibrium diagram should define the operating point of the arterial baroreflex. Both carotid sinuses were isolated in 16 halothane-anesthetized rats. The vagi and aortic depressor nerves were cut bilaterally. Carotid sinus pressure (CSP) was sequentially altered in 10-mmHg increments from 80 to 160 mmHg while sympathetic efferent nerve activity (SNA) and systemic arterial pressure (SAP) were recorded simultaneously under various hemorrhagic conditions. The mechanoneural arc was characterized by the response of SNA to CSP and the neuromechanical arc by the response of SAP to SNA. We parametrically analyzed the relationship between input and output for each arc using a four-parameter logistic equation model. In baseline states, the two arcs intersected each other at the point at which the instantaneous gain of each arc attained its maximum. Severe hemorrhage lowered the gain and offset of the neuromechanical arc and moved the operating point, whereas the mechanoneural arc remained unchanged. The operating points measured under the closed-loop conditions were indistinguishable from those estimated from the intersections of the two arc curves on the equilibrium diagram. The average root mean square errors of estimate for arterial pressure and SNA were 2 and 3%, respectively. Such an analytic approach could explain a mechanism for the determination of the operating point of the sympathetic baroreflex system and thus helps us integratively understand its function.  (+info)

Carotid baroreflex function during prolonged exercise. (7/508)

The present investigation was designed to uncouple the hemodynamic physiological effects of thermoregulation from the effects of a progressively increasing central command activation during prolonged exercise. Subjects performed two 1-h bouts of leg cycling exercise with 1) no intervention and 2) continuous infusion of a dextran solution to maintain central venous pressure constant at the 10-min pressure. Volume infusion resulted in a significant reduction in the decrement in mean arterial pressure seen in the control exercise bout (6.7 +/- 1.8 vs. 11.6+/- 1.3 mmHg, respectively). However, indexes of central command such as heart rate and ratings of perceived exertion rose to a similar extent during both exercise conditions. In addition, the carotid-cardiac baroreflex stimulus-response relationship, as measured by using the neck pressure-neck suction technique, was reset from rest to 10 min of exercise and was further reset from 10 to 50 min of exercise in both exercise conditions, with the operating point being shifted toward the reflex threshold. We conclude that the progressive resetting of the carotid baroreflex and the shift of the reflex operating point render the carotid-cardiac reflex ineffectual in counteracting the continued decrement in mean arterial pressure that occurs during the prolonged exercise.  (+info)

Chronic hypoxia enhances the phrenic nerve response to arterial chemoreceptor stimulation in anesthetized rats. (8/508)

Chronic exposure to hypoxia results in a time-dependent increase in ventilation called ventilatory acclimatization to hypoxia. Increased O(2) sensitivity of arterial chemoreceptors contributes to ventilatory acclimatization to hypoxia, but other mechanisms have also been hypothesized. We designed this experiment to determine whether central nervous system processing of peripheral chemoreceptor input is affected by chronic hypoxic exposure. The carotid sinus nerve was stimulated supramaximally at different frequencies (0.5-20 Hz, 0.2-ms duration) during recording of phrenic nerve activity in two groups of anesthetized, ventilated, vagotomized rats. In the chronically hypoxic group (7 days at 80 Torr inspired PO(2)), phrenic burst frequency (f(R), bursts/min) was significantly higher than in the normoxic control group with carotid sinus nerve stimulation frequencies >5 Hz. In the chronically hypoxic group, peak amplitude of integrated phrenic nerve activity ( integral Phr, percent baseline) or change in integral Phr was significantly greater at stimulation frequencies between 5 and 17 Hz, and minute phrenic activity ( integral Phr x f(R)) was significantly greater at stimulation frequencies >5 Hz. These experiments show that chronic hypoxia facilitates the translation of arterial chemoreceptor afferent input to ventilatory efferent output through a mechanism in the central nervous system.  (+info)

*Carotid sinus

Massage of the carotid sinus, carotid sinus massage is used to diagnose carotid sinus syncope and is sometimes useful for ... a condition known as carotid sinus hypersensitivity, carotid sinus syndrome or carotid sinus syncope, in which manual ... The carotid sinus extends from the bifurcation to the "true" internal carotid artery. The carotid sinus is sensitive to ... Carotid sinus reflex death - a theory and its history. URL last accessed February 28, 2006. "Carotid Sinus strike/slap as an ...

*Branch of glossopharyngeal nerve to carotid sinus

... and then divides in the angle of the bifurcation of the common carotid artery to innervate the carotid body and carotid sinus. ... that innervates the carotid sinus and the carotid body. It is a branch of the glossopharyngeal nerve that runs downwards, ... It carries impulses from the baroreceptors in the carotid sinus to the vasomotor center in the brainstem (to help maintain a ... The branch of glossopharyngeal nerve to the carotid sinus (Hering's nerve) is a small nerve in the neck, ...

*Czermak-Hering test

"Apparatus and method for measurement of digital pressure applied to carotid sinus for causing carotid sinus syndrome". Acta ... Johann Nepomuk Czermak stated that mechanical compression of the carotid artery due to the carotid sinus reflex initiates a ... The Czermak-Hering test is a vagal maneuver consisting of the application of external digital pressure to the carotid sinus. ... Carotid sinus massage Takino, Masuichi; Takino, Yoshitada; Sugahara, Kunikazu (March 1964). " ...

*Sinus bradycardia

as in carotid sinus syndrome, acute myocardial infarction. ECG characteristics Rate: Less than 60 beats per minute. Rhythm: ... Sinus bradycardia is a sinus rhythm with a rate that is lower than normal. In humans, bradycardia is generally defined to be a ... Sinus bradycardia can also be an adaptive advantage; for example, diving seals may have a heart rate as low as 12 beats per ... Sinus bradycardia is a common condition found in both healthy individuals and those who are considered well conditioned ...

*Pathophysiology of hypertension

Chapleau MW, Hajduczok G, Abboud FM (July 1992). "Suppression of baroreceptor discharge by endothelin at high carotid sinus ...

*Takayasu's arteritis

Fainting may result from subclavian steal syndrome or carotid sinus hypersensitivity. There is also often anemia and marked ... Due to obstruction of the main branches of the aorta, including the left common carotid artery, the brachiocephalic artery, and ...

*Strangling

... the rapidity of death can be affected by the susceptibility to carotid sinus stimulation. Carotid sinus reflex death is ... Passig, K. Carotid Sinus reflex death - a theory and its history. www.datenschlag.org. URL last accessed February 28, 2006. ... Stimulation of the carotid sinus reflex-causing bradycardia, hypotension, or both. Depending on the particular method of ... Incomplete occlusion of the carotid arteries is expected and, in cases of homicide, the victim may struggle for a period of ...

*Reflex syncope

Carotid sinus syncope is due to pressure on the carotid sinus in the neck. The underlying mechanism involves the nervous system ... Reflex syncope is divided into three types: vasovagal, carotid sinus, and situational. Vasovagal syncope is typically triggered ...

*Renin-angiotensin system

This loss of pressure is interpreted by baroreceptors in the carotid sinus. It can also be activated by a decrease in the ...

*Paroxysmal supraventricular tachycardia

Carotid sinus massage, carried out by firmly pressing the bulb at the top of one of the carotid arteries in the neck, is ... "BestBets: Comparing Valsalva manoeuvre with carotid sinus massage in adults with supraventricular tachycardia". Archived from ... is often not recommended in the elderly due to the potential risk of stroke in those with atherosclerotic plaque in the carotid ...

*Massage

Carotid sinus massage is used to diagnose carotid sinus syncope and is sometimes useful for differentiating supraventricular ... "Comparison of treatment of supraventricular tachycardia by Valsalva maneuver and carotid sinus massage". Ann Emerg Med. 31 (1 ...

*Valsalva maneuver

"Comparison of Treatment of Supraventricular Tachycardia by Valsalva Maneuver and Carotid Sinus Massage". Annals of Emergency ... or to clear the ears and sinuses (that is, to equalize pressure between them) when ambient pressure changes, as in diving, ... the existence of a connection between the oral cavity and the maxillary sinus. The Valsalva maneuver is used to aid diagnosis ...

*High pressure receptors

... are the baroreceptors found within the aortic arch and carotid sinus. They are only sensitive to blood ...

*Pathophysiology of heart failure

This destimulates baroreceptors in the carotid sinus and aortic arch which link to the nucleus tractus solitarii. This center ...

*Electrical muscle stimulation

... such as carotid sinus nerves, across the chest, or across the brain; caution in the use during pregnancy, menstruation, and ...

*Brodmann area 15

It therefore receives input from the carotid sinus relaying blood pressure and blood chemistry information to the brain. The ... nerve gets this information from baroreceptors and chemoreceptors located in the carotid artery. This region has been shown to ...

*Simhasana

... to aid better functioning of the carotid sinus, the sinus nerves, the larynx, and the thyroid and parathyroid glands. The ... carotid bodies assist in maintaining normal blood pressure and heartbeats. The breathing exercise is claimed to help the chest ...

*Syncope (medicine)

This type of syncope may also occur when an area in the neck known as the carotid sinus is pressed. The final type of syncope ... More specific tests such as implantable loop recorders, tilt table testing or carotid sinus massage may be useful in uncertain ... Likewise, using carotid ultrasonography on the premise of identifying carotid artery disease as a cause of syncope also is not ... Sick sinus syndrome, a sinus node dysfunction, causing alternating bradycardia and tachycardia. Often there is a long pause ...

*Glossopharyngeal nerve

Sensory fibers arise from the carotid sinus and carotid body at the common carotid artery bifurcation, ascend in the sinus ... It receives visceral sensory fibers from the carotid bodies, carotid sinus. It supplies parasympathetic fibers to the parotid ... This component of CN IX innervates the baroreceptors of the carotid sinus and chemoreceptors of the carotid body. Peripheral ... carries visceral sensory information from the carotid sinus and carotid body. General sensory (general somatic afferent) - ...

*Choking game

For those susceptible to carotid sinus syncope, of which most people would be unaware until it occurred, this can be an ... Unconsciousness may be induced by other methods although these are controversial: pressure over the carotid sinus may induce ... that pressure on the vagus nerve causes changes to pulse rate and blood pressure and is dangerous in cases of carotid sinus ... or hands or arm pressure on the neck compresses the internal carotid artery. Apart from the direct restriction of blood to the ...

*Brugada syndrome

There is a case report of a patient who died while shaving, presumed due to the vagal stimulation of the carotid sinus massage ... but patients with Brugada syndrome are also more likely to experience abnormally slow heart rhythms such as sinus node ...

*Reflex bradycardia

The baroreceptors in the carotid sinus sense this increase in blood pressure and relay the information to the cardiovascular ...

*Azotemia

If the decrease in blood pressure is systemic (rather than occlusion of the renal artery) baroreceptors in the carotid sinus ...

*Chokehold

It digs the blade of the wrist into the carotid sinus similar to the hand clasp method and uses a lever motion helped by the ... carotid restraints or sleeper holds are a form of strangulation that compress one or both carotid arteries and/or the jugular ... It is not an air choke but a carotid choke created entirely by the attacker's arms. Von Flue choke - this choke is mostly used ... In contrast, if the airway rather than the carotid arteries is blocked, the subject cannot breathe, but his brain is still ...

*Diving reflex

... allowing the valsalva maneuver or carotid sinus massage to be more appropriate.[clarification needed] Underwater diving portal ... Gross, P. M; Whipp, B. J; Davidson, J. T; Koyal, S. N; Wasserman, K (1976). "Role of the carotid bodies in the heart rate ... Preliminary evidence indicates that the bilateral carotid bodies detect the decreasing oxygen and rising carbon dioxide levels ...

*List of ICD-9 codes 390-459: diseases of the circulatory system

427.8) Other specified cardiac dysrhythmias (427.81) Sick sinus syndrome (427.89) Sinus bradycardia, NOS (427.9) Cardiac ... Dissection of carotid artery (443.22) Dissection of iliac artery (443.23) Dissection of renal artery (443.24) Dissection of ... Occlusion and stenosis of carotid artery (433.2) Occlusion and stenosis of vertebral artery (434) Occlusion of cerebral ... Nonpyogenic thrombosis of intracranial venous sinus (437.7) Transient global amnesia (438) Late effects of cerebrovascular ...
Carotid sinus reflex interactions were studied in 10 dogs anesthetized with pentobarbital sodium. The right and left carotid sinus regions were isolated and perfused at controlled pressures. Pressure in the right and left carotid sinuses were independently varied, and the resulting steady-state reflex changes in arterial pressure, heart rate, respiratory frequency, tidal volume, and total ventilation were measured. Reflex changes when carotid sinus pressure was changed on one side were strongly influenced by pressure in the contralateral carotid sinus (P less than 0.05). Right carotid sinus gain was found to be 0.628 +/- 0.058 at a left carotid sinus pressure of 50 mmHg and 0.148 +/- 0.027 when left carotid sinus pressure was 200 mmHg. Similar results were found for left carotid sinus gain. Suppression was also found for heart rate, respiratory rate, tidal volume, and total ventilation. The hypothesis that rapid resetting of one carotid sinus baroreflex might influence responses from the other ...
Synonyms for Carotid sinus reflex in Free Thesaurus. Antonyms for Carotid sinus reflex. 26 synonyms for reflex: automatic, spontaneous, instinctive, involuntary, impulsive, knee-jerk, unthinking, automatic, impulsive, instinctive, involuntary.... What are synonyms for Carotid sinus reflex?
The carotid sinus baroreceptor reflex was studied in 11 normotensive subjects, using a variable pressure neck chamber and correcting for imperfect pressure transmission to the carotid sinus. Decreased carotid baroreceptor stimulation caused a sustaineded rise in arterial pressure, and increased carotid baroreceptor stimulation caused a sustain fall. The responses were in linear relation to the stimulus, and, after reaching the steady state, greater for the reduced than for the increased baroreceptor stimulation. Thus the carotid sinus baroreceptor reflex of the normotensive man is an effective antihypotensive and antihypertensive feedback system, though the former function may have more sensitivity. The increased and decreased baroreceptor stimulation by the neck chamber also caused bradycardia and tachycardia which were modest in magnitude and often transient. In eight subjects the reflex changes in heart rate induced by the neck chamber were compared with those induced by altering transmural ...
In human anatomy, the carotid sinus is a dilated area at the base of the internal carotid artery just superior to the bifurcation of the internal carotid and external carotid at the level of the superior border of thyroid cartilage. The carotid sinus extends from the bifurcation to the "true" internal carotid artery. The carotid sinus is sensitive to pressure changes in the arterial blood at this level. It is the major baroreception site in humans and most mammals. The carotid sinus is the reflex area of the carotid artery, consisting of various nerve receptors for baroregulation (pressure regulation of the body in sync to external conditions). The carotid sinus contains numerous baroreceptors which function as a "sampling area" for many homeostatic mechanisms for maintaining blood pressure. The carotid sinus baroreceptors are innervated by the sinus nerve of Hering, which is a branch of cranial nerve IX (glossopharyngeal nerve). The glossopharyngeal nerve synapses in the nucleus tractus ...
The major new finding obtained from conscious rats was the clear-cut demonstration that chemoreceptors, as well as baroreceptors, were transiently activated during combined electric stimulation of the carotid sinus and the carotid sinus nerve in conscious rats. The results have shown that when the carotid bifurcation was intact (ie, in the CONT group), combined electric stimulation of the carotid sinus and the carotid sinus nerve elicited a significant hypotensive response. This finding is in line with results obtained in dogs21,22 and drug-resistant hypertensive patients.1,2 Nevertheless, unlike the results seen in dogs23 and drug-resistant hypertensive patients,4 HR did not significantly decrease in intact conscious rats (the CONT group).. It is of interest to note that bilateral carotid body denervation (as in the CHEMO-X group) hampered the hemodynamic influences of the carotid chemoreceptors during combined electric stimulation of the carotid sinus and the carotid sinus nerve in conscious ...
Objective: To determine the frequency, age distribution and clinical presentation of carotid sinus hypersensitivity (CSH) among 373 patients (age range 15-92 years) referred to two autonomic referral centres during a 10-year period.. Methods: Carotid sinus massage (CSM) was performed both supine and during 60° head-up tilt. Beat-to-beat blood pressure, heart rate and a three-lead electrocardiography were recorded continuously. CSH was classified as cardioinhibitory (asystole ⩾3 s), vasodepressor (systolic blood pressure fall ⩾50 mm Hg) or mixed. All patients additionally underwent autonomic screening tests for orthostatic hypotension and autonomic failure.. Results: CSH was observed in 13.7% of all patients. The diagnostic yield of CSM was nil in patients aged ,50 years (n = 65), 2.4% in those aged 50-59 years (n = 82), 9.1% in those aged 60-69 years (n = 77), 20.7% in those aged 70-79 years (n = 92) and reached 40.4% in those ,80 years (n = 57). Syncope was the leading clinical symptom in ...
The goal of this study was to determine whether nitric oxide (NO) and the NO donor, S-nitrosocysteine (cysNO), modulate the activity of carotid sinus baroreceptors. Baroreceptor activity was recorded from the vascularly isolated carotid sinus in anesthetized rabbits. Baroreceptor activity decreased in a dose-dependent manner after injection of either NO or cysNO as constant pressure was maintained, and activity recovered spontaneously over time, within seconds to minutes. The baroreceptor pressure-activity relation was shifted significantly to the right by cysNO, with a profound suppression of activity at high pressure. Baroreceptor activity at 160 mm Hg averaged 76 +/- 8%, 60 +/- 6%, and 36 +/- 5% of the control maximum during exposure to 10(-4), 2 to 3 x 10(-4), and 10(-3) mol/L cysNO, respectively. The inhibition of activity by the L and D isomers of cysNO was equivalent and was blocked by reduced hemoglobin, suggesting that the effect was mediated by NO. The suppression of baroreceptor activity by
Introduction: White matter hyperintensities (WMH) on MRI are common in older people and are associated with cognitive impairment, falls and depression. They are believed to represent cerebrovascular small vessel disease but as frank infarction is not always seen it is suggested that WMH represent damage resulting from hypoperfusion. Carotid sinus hypersensitivity (CSH) is an exaggerated fall in blood pressure (BP) or heart rate (HR) in response to stimulation of the carotid sinus. It is defined as a ≥50 mmHg drop in systolic BP & / or ≥3 second asystole in response to carotid sinus massage (CSM). CSH, is often associated with syncope & presyncope, thought to indicate cerebral hypoperfusion.. Aim: To examine, over a ten year follow-up, if CSH is associated with WMH volume.. Method: In 2002, 274 people age ≥65 underwent CSM. BP & HR response were recorded using beat to beat monitoring. Symptoms suggestive of cerebral hypoperfusion e.g. syncope or presyncope were recorded. In 2012, 53 of ...
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1. Carotid baroreceptor manipulation (neckchamber technique) and passive head-up tilting were used in ten patients with renovascular hypertension and in five subjects with essential hypertension under diuretic treatment to study reflex control of renin secretion" at high basal-renin production rates.. 2. Reflex effects of carotid baroreceptor manipulation on renin secretion were only minor. During baroreceptor deactivation there was a moderate increase in mean arterial pressure, but an inconsistent change in the renal venous-arterial difference in plasma renin activity (PRA).. 3. During baroreceptor stimulation there was a modest fall in mean arterial pressure and a marked rise in the renal venous-arterial difference in PRA. This was opposite to the fall which might have been predicted as a result of the sympathetic depressor influence of the baroreceptor stimulus. Conversely, tilting increased the venous-arterial PRA difference by about 200%.. 4. It is concluded that when renin production rate ...
The purpose of this study was to examine the role of carotid sinus and cardiopulmonary mechanoreceptors in the reflex control of adrenal medullary catecholamine secretion. Afferent input from carotid sinus and cardiopulmonary mechanoreceptors was decreased by carotid occlusion or cervical vagal cold block, respectively. Increases in arterial pressure were significantly greater when either intervention was tested in the presence of the other, with the role of the carotid sinus baroreflex being dominant. Neither carotid occlusion nor vagal cold block resulted in a significant increase in plasma epinephrine or norepinephrine concentrations. However, carotid occlusion during vagal block caused a significant increase in plasma epinephrine (+87%) and norepinephrine concentrations (+128%). Likewise, vagal block during carotid occlusion increased plasma epinephrine (+82%) and norepinephrine concentrations (+73%). Similar experiments performed in a group of chemically sympathectomized animals ...
The goal of the present study was to determine whether oxygen-derived free radicals contribute to baroreceptor dysfunction in atherosclerosis. Baroreceptor activity was measured from the carotid sinus nerve during pressure ramps in isolated carotid sinuses of anesthetized rabbits. Rabbits fed a 0.5% to 1.0% cholesterol diet for 7.9 +/- 0.4 months (mean +/- SE; range, 5.5 to 10) developed atherosclerotic lesions in the carotid sinuses. Maximum baroreceptor activity measured at 140 mm Hg and the slope of the pressure-activity curve were reduced in atherosclerotic (n = 15) compared with normal (n = 13) rabbits (425 +/- 34 versus 721 +/- 30 spikes per second and 6.2 +/- 0.6 versus 10.8 +/- 0.8 spikes per second per mm Hg, respectively, P | .05). The level of activity was inversely related to plasma cholesterol concentration (r = .86, P | .001) and total cholesterol load (plasma concentration x duration of diet, r = .92). Mean arterial pressure was normal in both groups. Exposure of the carotid sinus to the
Title:The Future of Interventional Management of Hypertension: Threats and Opportunities. VOLUME: 12 ISSUE: 1. Author(s):Alexandros Briasoulis and George Bakris. Affiliation:5841 S. Maryland Ave MC 1027, Chicago, IL 60637, USA.. Keywords:Resistant hypertension, baroreflex activation therapy, renal sympathetic denervation.. Abstract:In about 48% hypertensive patients in the United States, blood pressure remains higher than accepted treatment targets despite broad availability of effective pharmaceutical agents. Of these 48%, recent estimates define about 10-11% have treatment-resistant hypertension (TR-HTN). Compensatory changes in sympathetic nervous system function are an important component of HTN. Recent technical advances targeting the sympathetic activity of the carotid sinuses (Baroreflex Activation Therapy-BAT) and the renal sympathetic nerves (Renal Denervation Therapy-RDT) have renewed interest in invasive therapy for the treatment of drug-resistant hypertension. Encouraging results ...
The hypothesis that we have formulated to explain the relationship between denervation and abnormal response to carotid sinus massage has been extensively described6 and is based on the theory of central gating.14 Briefly, chronic denervation of the muscle leaves the central nervous system without any moment-to-moment information about the contractile state of the muscle. On the other hand, the midbrain centers receive "normal" information from the stretch receptors of the carotid sinus. In a normal individual, carotid sinus massage, because of the anatomic position of the sternocleidomastoid muscle, results in a pressure on both the muscle and the sinus, and these signals are integrated by the centers as an "external" stretching of the sinus. In the case of proprioceptive defect of the muscle, the massage of the sinus is considered as a stretching of the sinus only and is integrated by the centers as an abrupt increase in blood pressure, resulting through the baroreflex pathways in an ...
An implantable device (20) uses the carotid baroreflex in order to control systemic blood pressure. The implant includes sampling and pulse stimulation electrodes (44) preferably located on the carotid sinus nerve branch of the glossopharyngeal nerve, adjacent and distal to the carotid sinus baroreceptors. The stimulators have an external control unit, which communicates with the implant for determining appropriate operational parameters, and for retrieving telemetry information from the devices data bank. Typically two internal devices are implanted, one at each side of the patients neck.
A quick reference on Carotid sinus syncope, covering the clinical presentation, investigative approach, and key principles of management
There are four main sinus cavities in the body. They are located on either side of the nose, behind and in-between the eyes, and in the forehead. Each sinus cavity has an opening into the nose for the exchange of air and mucous. When the cavities get filled with mucous it creates a perfect breeding ground for bacteria.. Some of the most common sinus pressure symptoms include severe nasal congestion and yellowish green discharge which is thick because it contains pus. Pain in the teeth is also very normal. This pain increases when you bend over. Symptoms may vary however, depending on the sinuses involved.. Sinus pressure symptoms normally occur for about ten days and they may carry on for a longer period if a cold or flu occurs. They normally worsen after five to seven days. In some cases fever also occurs. Fever is more common in children than in adults therefore it is not a very reliable way of diagnosing sinus pressure.. Far more severe sinus pressure symptoms are terrible headaches, pain or ...
The present experiments were designed to measure the direct effects of propranolol on carotid sinus pressoreceptor nerve activity in the semi-isolated, superfused sinus of the cat. Propranolol (5 microgram/ml) significantly enhanced carotid sinus nerve activity at perfusion pressures of 100, 150 and 250 mm Hg. The enhancement was due primarily to the recruitment of new fibers. In similar preparations, perfused at constant flow, propranolol increased sinus resistance in parallel with the increase in sinus discharge. These effects were rapidly dissipated by rinsing with drug-free perfusion solution. The evidence suggests that propranolol may produce a change in either the elastic or autoregulatory modalities of sinus smooth muscle. This may produce a functional "resetting" of the sinus and provide a mechanism to explain the antihypertensive effect of propranolol. ...
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Why is the Dim Mak effective? The carotid sinus is a special sensory organ regulating the pressure of blood flow to the brain. The carotid sinus is located over internal and external carotid arteries. When blood pressure is too high, the carotid sinus signals the vasomotor center of the brain to decrease the blood pressure by dilating peripheral blood vessels and slowing down heart rate. Thats why it can result in a loss of consciousness along with a build up of plaques in the carotid arteries. By striking this area, small tears can result in the carotid arteries and blood clots. Death can occur by striking this area. Thats why doctors look for a pulse because the carotid artery is a major indicator of life. A very helpful resource in understanding more on Dim Mak is Dr. Michael Kellys (a sports medical doctor) book "Death Touch: The Science of Dim Mak (1). In this book, he explains that stimulating a nerve through a Dim Mak point connected to an internal organ can cause damage ...
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The results from these studies demonstrate that afferent input from peripheral chemoreceptors and mechanoreceptors contributes little to the systemic hemodynamic and sympathetic responses after term delivery by cesarean section. Furthermore, birth-related increases in circulating norepinephrine but not epinephrine appear dependent on afferent input from the carotid sinus or aortic depressor nerves, which carry both chemo- and baroreceptor afferents from the carotid sinus and aortic arch, respectively. Finally, we observed that vagal afferent activity regulates basal fetal plasma ANG II levels and exerts a tonic inhibitory effect on AVP release after birth.. Both peripheral chemoreceptors and baroreceptors have been shown to be functional during fetal life. The fetal cardiovascular response to acute hypoxemia is well described, consisting of a decrease in heart rate and increase in peripheral vascular resistance (7). Carotid denervation abolishes these responses to hypoxemia and NaCN, a chemical ...
For the past week I have been fighting off what I thought was a sinus infection (sinus pressure, drainage, plugged up ears, headache, and an off/on fever). Starting about two or three days ago the fev...
Ways to relieve sinus pressure in the ears include nasal irrigation, drinking water, turmeric tea, and peppermint tea. Apply warm compress and inhale steam.
Why do you have a Spine?. You have a spine to connect the upper and lower portions of your body together. Through your spine runs your spinal cord which is the major thoroughfare between your brain and the rest of your body. Your spine is one of the most important aspects of your whole body.. What does your spine look like?. Your spine is made up of three main curves and the sacrum. There are twenty four vertebrae; 7 cervical, 12 thoracic, and 5 lumbar. The cervical are curved in a what is called a lordotic curve, the thoracic are curved the opposite direction or, kyphotic, and the lumbar are curved like the cervical, in a lordotic curve. A kyphotic curve is the primary curve and the lordotic curve is a secondary, or functional curve. A functional curve is one that does not show up until movement occurs.. The curves of your spine not only act as shock absorbers between your head and tail, but allow the head to be over your pelvis. Your spine allows you to stand upright and see the horizon! The ...
Alas! All is not a bed of roses in the world of cone beam imaging. With the improved technologies come increased responsibilities. A dentist might use his cone beam image for the reasons specific to his specialty, such as assessment for the adequacy of bone for implant placement, but if he or she does not recognize abnormal anatomical structures, he or she could be held legally responsible if the patient suffers future injuries relating to that missed observation. For example, if an adenocarcinoma has caused visible distortion or disintegration of any bony structure seen in the scan, the dentist is responsible for notifying the patient and referring the patient to an appropriate specialist, or baring that, for enlisting the help of a board certified radiologist to assess the images.. This also means that if the image includes the entire sinus region, the dentist is responsible for recognizing abnormalities in the sinus, even though this lies outside of his area of expertise and he has no ...
Breathe freely again by clearing blocked passageways and easing sinus pressure. According to research or other evidence, the following self-care steps may be helpful. Wipe out irritantsKeep your environment free of irritants and allergens that can trigger sinus congestion, such as dust, mold, smoke, chemical fumes, and...
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Looking for online definition of carotid sinus reflex in the Medical Dictionary? carotid sinus reflex explanation free. What is carotid sinus reflex? Meaning of carotid sinus reflex medical term. What does carotid sinus reflex mean?
Looking for online definition of carotid sinus in the Medical Dictionary? carotid sinus explanation free. What is carotid sinus? Meaning of carotid sinus medical term. What does carotid sinus mean?
Clinical trials on carotid receptor stimulation by an implantable device showed a significant reduction in both office systolic (22 or 34 mmHg) and diastolic (18 or 20 mmHg) blood pressure, 24-hour ambulatory blood pressure (14/9 mmHg), and heart rate (12 bpm), which was evident from study onset and was maintained at follow-up. Available data suggest a beneficial effect of carotid baroreceptor stimulation on the reversal of left ventricular hypertrophy and cardiac structure and function, with attenuated mitral A-valve velocity and reduced left atrial dimensions; also carotid baropacing does not impair the renal function of patients with resistant hypertension, even during prolonged follow-up periods (13-18).. ...
Arterial baroreceptors are mechanical sensors that detect blood pressure changes. It has long been suggested that the two arterial baroreceptors, aortic and carotid baroreceptors, have different pressure sensitivities. However, there is no consensus as to which of the arterial baroreceptors are more sensitive to changes in blood pressure. In the present study, we employed independent methods to compare the pressure sensitivity of the two arterial baroreceptors. Firstly, pressure-activated action potential firing was measured by whole-cell current clamp with a high-speed pressure clamp system in primary cultured baroreceptor neurons. The results show that aortic depressor neurons possessed a higher percentage of mechano-sensitive neurons. Furthermore, aortic baroreceptor neurons show a lower pressure threshold than that of carotid baroreceptor neurons. Secondly, uniaxial stretching of baroreceptor neurons, that mimics the forces exerted on blood vessels, elicited a larger increase in intracellular Ca2+
1. The carotid baroreceptors were stimulated for 2 min by neck suction at −30 and −60 mmHg in 19 normotensive subjects and 12 patients with moderate essential hypertension.. 2. Blood pressure was measured with a mercury sphygmomanometer and heart rate was derived from beat-to-beat analysis of the electrocardiogram. Blood flow was measured simultaneously at calf and finger with venous occlusion plethysmography and the vascular resistance was calculated.. 3. During neck suction at − 30 and − 60 mmHg there was a significant decrease in arterial blood pressure and heart rate. There was a transient vasodilatation of the calf blood vessels, while there was a sustained vasoconstriction of the finger blood vessels. These results were qualitatively similar in both groups; however, there were quantitative differences.. 4. These experiments show that there is a selective autonomic control of the different peripheral vascular beds by the carotid baroreceptors in both normotension and mild essential ...
1. Tachyphylaxis occurs when renin is repeatedly injected into dogs and cats regardless of whether they are normal, anesthetized, pithed, hepatectomized, suprarenalectomized, nephrectomized, or eviscerated.. 2. The pressor response to renin in brief experiments is independent of the height of the arterial pressure or the presence of the suprarenals. Evisceration and large doses of ergotamine reduce the response. It is largely uninfluenced by pithing, intracisternal injection of renin, cocaine, strychnine, caffeine, and infusion of sodium bicarbonate or hydrochloric acid. It may be slightly increased by large blood transfusions or hepatectomy but the result is short lived.. 3. There is no parallelism between the pressor responses to carotid sinus stimulation, adrenine, and tyramine on the one hand and renin on the other.. 4. Section of the brain may be followed by depressor responses to renin.. 5. Intracisternal injection of renin elicits no significant rise in blood pressure or other circulatory ...
The sick sinus syndrome is a disease of the sinus node and occurs in middle-aged and older patients, with some exceptions. The most probable predominant etiology is a degenerative process of the...
Adrenergic blocking action has been measured in a series of eighteen dibenzazepine derivatives. Maximal action was found in the allyl dibenzazepine derivative, Ro 2-3248. Compounds with side-chains longer than propyl were inactive. The quaternary salts were inactive.. The allyl dibenzazepine derivative, Ro 2-3248, is a strong, short-acting adrenergic blocking agent which causes a prolonged fall of blood pressure. It is orally active. Ro 2-3248 blocked the stimulatory action of epinephrine on blood pressure, nictitating membrane and isolated seminal vesicles. It blocked the stimulatory effects of arterenol. It also blocked the effects of sympathetic nerve stimulation on the nictitating membrane and the carotid sinus reflex. It did not block the inhibitory actions of epinephrine on blood pressure, isolated tracheal rings and isolated intestine or the inhibitory action of isopropylarterenol on blood pressure. The compound has a relatively low toxicity.. ...
Multidisciplinary assessment of the reason for the fall will reduce the risk of further fractures, and the components of such assessments are well described.11 12 Nearly all patients with hip fracture meet the criteria for such an assessment, which should be performed routinely as part of inpatient rehabilitation care (box 4). A medical cause for the fall should be sought; specifically, hypotension, postural hypotension, arrhythmia, vasovagal syncope, and carotid sinus hypersensitivity. Examination should include lying and standing blood pressure and a 12 lead electrocardiogram.. About 3% of hip fractures are related to localised bone weakness at the fracture site, secondary to tumour, bone cysts, or Pagets disease. More than half of the remaining patients have osteoporosis, and nearly all are osteopenic. Over the age of 80, a woman with normal bone mineral density for her age will have a T score of around - 2.5 (the diagnostic threshold for osteoporosis). Thus, assessment of bone density is ...
Systems and methods provide baroreflex activation to treat or reduce pain and/or to cause or enhance sedation or sleep. Methods involve activating the baroreflex system to provide pain reduction, sedation, improved sleep or some combination thereof. Systems include at least one baroreflex activation device, at least one sensor for sensing physiological activity of the patient, and a processor coupled with the baroreflex activation device(s) and the sensor(s) for processing sensed data received from the sensor and for activating the baroreflex activation device. In some embodiments, the system is fully implantable within a patient, such as in an intravascular, extravascular or intramural location.
Afferent fibres from CNIX and CNX travel to the NTS in the medulla. Effector neurons from the RVLM are GABAergic and therefore inhibitory, i.e. increased baroreceptor discharge reduces tonic sympathetic tone and increases vagal tone.. Increased baroreceptor activity therefore results in:. ...
1. Irrigate your nasal passageways. Allergen particles, like bacteria, dust, pollen and others are washed off when a nasal rinse is done because it cleans out our mucus membranes and prevents the formation of more bacteria. The purpose of the mucus on our faces is to fight infections and, thereby, eliminate the incidence of sinusitis. Over the counter medications and nasal irrigation products are available and most have been found to be very effective. To know if a particular nasal irrigation product is fit for you, consult an ear, nose and throat doctor.When doing an assignment on Sinus Pressure, it is always better to look up and use matter like the one given here. Your assignment turns out to be more interesting and colorful this way ...
Looking for Baroreceptors? Find out information about Baroreceptors. sensory nerve terminals in blood vessels that perceive changes in blood pressure and reflexly regulate its level. Baroreceptors become stimulated when the... Explanation of Baroreceptors
If the error occurs frequently, request an RMA in order to replace the 6148A module, and mark the module for EFA.%LTL-SP-2-LTL_PARITY_CHECK: LTL parity check request for 0x[hex]ExplanationThis is the result of The outputs of the atrial and ventricular sensing circuits, 82 and 84, are connected to the microcontroller 60 which, in turn, are able to trigger or inhibit the atrial and ventricular No. 4,788,980 (Mann et al.). See the illustration on the side access panel for the correct memory configurations, and reseat the DIMMs accordingly. 216-Memory Size Exceeds Maximum Supported The amount of memory installed exceeds that supported The error is thus corrected and processing returns to FIG. 3. As used herein, the phrase "coronary sinus region" refers to the vasculature of the left ventricle, including any portion of the coronary sinus, great cardiac vein, left marginal vein, left posterior The switch was still under warranty from the used hardware > reseller, so the blade was replaced. Imprecise ...
As this is a potentially perilous procedure, the doctor usually performs it in conditions that take into consideration test sensitivity. For example, the massage table would be tilted at an angle of 70 degrees. Explaining to the patient the possible side effects and checking for contraindications should be done before the message.. The physician would ask the patient to relax and lie down on their back having extended the neck and turn the head so that the side that is being rubbed is facing upwards. A cardiac monitor would also be attached to the patient in order to monitor the heart rate. Once the patient has been in this position for five minutes, the massage can be performed. Imagine a horizontal line that begins about an inch and a half below the earlobe. Place the tips of the index and middle finger here. Applying the amount of pressure you would use to indent a tennis ball, massage the area in a counter-clockwise circle. Identify the carotid sinus and massage gently applying steady ...
I dont get sinus infection issues, so I dont know if thats related to the flu/common cold brain fog. My pet neurological theory is that the dopamine levels in the system go down, but if thats true I dont have any idea why that happens -- or maybe thats how the body forces one to rest and the brain fog and irritability is a side effect. Also side effects from any medication taken shouldnt be ruled out -- antihistamines can have a sort of brain fog effect (the 70s antihistimine du jour Actifed comes to mind ...
How to Massage Your Sinuses. If you are suffering from sinus pressure or congestion, massaging your sinuses may help to alleviate some of your irritation. Massaging the sinuses and the tissues surrounding the sinuses can help relieve the...
Nasal trauma can cause a deviated septum, but some people are simply born with the condition. Some of the symptoms or side effects of this condition include:
Hi ladies Thanks again for all your replies in this forum. I never thought I would make it to pass the 6 mo mark... DD is almost 10mo!!! Anyway, DD has been sick this week, pink eye/congestion and this morning I woke up with sore throat and a lot of sinus pressure. Im thinking is allergies because of all the crazy pollen out there now! Ive been feeling not very well through the day and I was wondering if there is anything at all I could take to at least calm the sinus pressure or the
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Doctor, I have been experiencing something for over a week now. Its a pressure in my head, feels very similar to sinus pressure, but paired with it is a shortness of breath, a difficulty seeing, slight cough at times, feeling faint and di
Nasty snot in the mask is a common issue and another one of the unladylike things I suffer with. I experience often. I am one of those many people across America and especially in Florida who struggle with sinus pressure and pain. Rich will tell you that I can tell him when a good strong…
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Baroreceptor activity and postural blood volume changes were evaluated in four normotensive and nine hypertensive uremic patients before and after bilateral nephrectomy. Baroreceptor activity, reflected by the slope of linear regression of R-R interval with drug-induced systolic blood pressure elevation, was significantly lower in hypertensive than in normotensive patients. Six of nine patients had normal blood pressure following bilateral nephrectomy; however, the mean slopes of all nine patients, irrespective of postnephrectomy blood pressure, approached that of normotensive uremic patients. The slopes of both normotensive and hypertensive patients, before and after bilateral nephrectomy, were significantly less than normal controls. Similar results were found in lowering blood pressure with amyl nitrite.. Depressed baroreceptor activity is suggested to be secondary to neuropathy of the autonomic nervous system, chronic hypertension, heart disease, and anemia. It is speculated that this ...
From these findings, several perioperative anesthetic implications2 can be anticipated during resection. First, because a carotid body paraganglioma is a neuroendocrine tumor, release of catecholamines or association with a pheochromocytoma should be suspected. Endocrine evaluation will determine if preoperative α-blockade is needed to prevent intraoperative hypertensive crises. The tumor blush from the neoplastic vascular proliferation is indicative of an increased risk of profuse hemorrhage. Consequently, tumor biopsy is contraindicated. Preoperative tumor embolization should be considered3 and the need for rapid blood transfusion anticipated. The ICA plaque may lead to cerebrovascular accidents by obstruction of cerebral blood flow and by embolic stroke from plaque dislodgement during ICA dissection. Finally, tumor invasion may lead to carotid sinus hypersensitivity, and carotid sinus manipulation may precipitate severe bradycardia ...
Inclusion Criteria:. General:. A. Undergoing primary pacemaker implantation B. Able to appear for outpatient follow-up C. Age , 18 years. Symptoms:. D. Syncope or E. Dizzy spells or F. Congestive heart failure. Electrocardiographic:. G. Sinus bradycardia ,40/minute for at least 1 minute in a conscious awake state or H. Sinus arrest/sinoatrial block ,2 seconds or I. Bradycardia/tachycardia with sinus-pauses ,2 seconds. Exclusion Criteria:. Clinical:. A. Malignant disease. B. Severe psychogenic disease including severe decrepitude and dementia. C. Impending larger operation expected to influence the major end point. D. Cardiac disorder expected to need cardiac surgery during the follow-up period.. E. Need for other device implantation: ICD (implantable cardioverter defibrillator) or implantable DC converter (for atrial fibrillation).. F. Carotid sinus syndrome (positive carotid sinus massage with pauses ,3 seconds).. Electrocardiographic:. G. Atrioventricular block. H. Bundle-branch block ...
Afferent chemoreceptor activity was recorded from the peripheral cut end of the carotid sinus nerve in pentobarbitone anaesthetized cats. The effects of purines, peptides and ouabain on chemosensory activity were studied. Purines. It was found that intracarotid injections of adenosine: AMP; ADP; ATP; CoA;Me-adenosine analogues: N6-methyladenosine, 2-chloroadenosine, 3-deoxyudenosine but not 2-deoxyadenosine; cyclic AMP; dibutyryl cyclic AMP increased spontaneous chemoreceptor discharge. The ATP analogues, a-5- methylene ATP decreased spontaneous chemoreceptor discharge, whereas the f-y-methylene ATP caused a slight increase in discharge. Adenine and the purine nucleosides inosine and guanosine had little or no effect on the discharge. The pyrimidine nucleosides cytidine and uridine were also studied and had little or no effect on spontaneous chemoreceptor discharge. Intracarotid injection of theophylline transiently depressed spontaneous chemosensory activity and potentiated the action of ...
The Bezold-Jarisch reflex (also called the Jarisch-Bezold reflex or Von Bezold-Jarisch) involves a variety of cardiovascular and neurological processes which cause hypopnea (excessively shallow breathing or an abnormally low respiratory rate) and bradycardia (abnormally low resting heart rate). Prolonged upright posture results in some degree of pooling of blood in the lower extremities that can lead to diminished intracardiac volume. This phenomenon is exacerbated if the individual is dehydrated. The resultant arterial hypotension is sensed in the carotid sinus baroreceptors, and afferent nerve fibers from these receptors trigger autonomic signals that increase cardiac rate and contractility. However, pressure receptors in the wall and trabeculae of the underfilled left ventricle may then sense stimuli, activating high-pressure C-fiber afferent nerves from these receptors. They may respond by sending signals that trigger paradoxical bradycardia and decreased contractility, resulting in ...
Syncope is a common medical problem, with a frequency between 15% and 39%. In the general population, the annual number episodes are 18.1-39.7 per 1000 patients, with similar incidence between genders. The first report of the incidence of syncope is 6.2 per 1000 person-years. However, there is a significant increase in the incidence of syncope after 70 years of age with rate annual 19.5 per thousand individuals after 80 years. It presents a recurrence rate of 35% and 29% of physical injury. Among the causes of syncope, the mediated neural reflex, known as neurocardiogenic or vasovagal syncope, is the most frequent. The others are of cardiac origin, orthostatic hypotension, carotid sinus hypersensitivity, neurological and endocrinological causes and psychiatric disorders. The diagnosis of syncope can be made by clinical method associated with the electrocardiogram in up 50% of patients. Its prognosis is determined by the underlying etiology specifically the presence and severity of cardiac disease. The
A 51 year old man, with a previous history of 15 years of hypertension treated with β blockers, complained of nocturnal and early morning seizures. One year ago, he had a syncope thought to be caused by bradycardia. β Blockers were reduced in a first step, and then discontinued. Serial neurological investigations were normal. Therapeutic challenges using sodium valproate or phenytoin did not had any favourable influence. Glucose metabolism was normal.. Cardiac investigations including carotid sinus massage, recording of late potentials, repetitive 24 hour Holter monitoring, and tilt table testing were normal. At electrophysiological testing, AH interval was 80 ms, and HV interval was 42 ms. Sinus node function and anterograde atrioventricular conduction were normal. Programmed atrial and ventricular stimulation did not induce any sustained arrhythmia. The ajmaline test was negative.. A Reveal Plus implantable loop recorder (Medtronic) was implanted. One month later, at the follow up visit, the ...
Increased sympathetic activity is a well-known pathophysiological mechanism in insulin resistance (IR) and hypertension (HT). The carotid bodies (CB) are peripheral chemoreceptors that classically respond to hypoxia by increasing chemosensory activity in the carotid sinus nerve (CSN), causing hyperventilation and activation of the sympathoadrenal system. Besides its role in the control of ventilation, the CB has been proposed as a glucose sensor implicated in the control of energy homeostasis. However, to date no studies have anticipated its role in the development of IR. Herein, we propose that CB overstimulation is involved in the etiology of IR and HT, core metabolic and hemodynamic disturbances of highly prevalent diseases like the metabolic syndrome, type 2 diabetes, and obstructive sleep apnoea. We demonstrate that CB activity is increased in IR animal models and that CSN resection prevents CB overactivation and diet-induced IR and HT. Moreover, we show that insulin triggers CB, ...
The sinuses are hollow cavities in the head, that are normally filled with one of materials - mucus and air. In a few cases, however, a 3rd type of substance may be discovered sitting inside your sinuses - foreign substances. These can range from plain antique dirt, molds, pollen, and smoke, to infectious micro organisms like bacteria, viruses and fungi. When these overseas materials stay put in your sinuses, those can motive sinusitis.. Sinusitis is the infection of the sinuses which could purpose nasal congestion, headaches, a runny nostril, and other pains near the sinus regions just like the face and teeth. Fighting this circumstance involves exceptional types of methods, which includes utility of home remedies, taking in medication, or virtually resting and expecting sinusitis to head away on its very own. The closing one is without a doubt your nice bet while managing viral sinusitis.. Nasal ...
The present invention provides systems, devices, and methods for using the same for activating (stimulating) the baroreflex system of a patient using a baroreflex activation system with incrementally changing therapy intensity by sensing/monitoring/interpreting sensed data.
ok, I have called my doctor but she stated its going around and you have to let it run it course. I know its my sinuses because it happens quite often!! Started last night; pain all in my face (eyes,...
To get back to the original intent of the post, I believe that a Shoken into the Carotid Sinus with good intent should be Practiced incessantly by all, But especially by Women. This is an accessable point even during severe grappling and will drop the assailants Blood Pressure so rapidly as top cause unconsciousness. If nails arent long then you can even grab the collar bone ate the St-11, just beside the sternal notch and roll your hand into a fist (Sanchin Kata) and hit the Herrings Nerve which ties into the Vegas Nerve, also a branch of the Seventh Cranial Nerve, bunch of good stuff. Kyoshi Canna witnessed me perform this KO on a very Large man with an instant KO. This dosnt work as well on a short thick neck, but a Skoken to the Carotid will still cause a major affect, so follow up will be easier ...
Sinus & Nasal Congestion Decongestant Medicine When nasal congestion or sinus pressure build, it can feel like a ton of bricks have landed on your head. However, many Mucinex Sinus-Max® products are designed to help clear up your stuffy nose, relieve headaches and thin and loosen excess mucus. Get the answers to co
Baroreceptors are sensory nerve endings in human blood vessels that detect blood pressure. There are two types of barorecptors...
Temporarily relieves these symptoms associated with the common cold or flu: headache, fever, sinus pressure, nasal congestion, minor body aches and pains....
Three studies, involving altogether 101 patients, have focused on patient cohorts with presumed and re-evaluated seizure disorders.13-15 One hundred of them were treated with, but were unresponsive to, AED therapy. In these studies it was confirmed that vasovagal syncope may be accompanied by myoclonus, as well as carotid sinus hypersensitivity and primary arrhythmias such as bradycardia, caused by sinus node dysfunction and intermittent atrioventricular (AV) block, as well as ventricular (torsade de pointe) and, more rarely, supraventricular tachycardia.. Certain features might prompt the re-evaluation of a diagnosis of presumed epilepsy and engage the cardiologist. The diagnostic strategy can be chosen based on the age of the individual patient: in the very young patient the efforts should be directed towards vasovagal syncope or variants of the long QT syndrome, while in older patients sinus node disease or intermittent high degree AV block should be looked for; in the highest age group ...
... this image shows the pathway of the baroreceptor reflex the reflex that shares in the control of normal blood pressure showing: 1. aortic baroreceptor 2. aortic body 3. carotid sinus 4. carotid baroreceptor 5. inferior ganglion of vagus nerve for th
Carotid baroreflex activation has been demonstrated to provide enduring reductions in arterial blood pressure. The aim of this study was to investigate the effect of long-term therapy on renal function. A total of 322 patients were enrolled in the Rheos Pivotal Trial. Group 1 consisted of 236 patients who started baroreflex activation therapy 1 month after device implantation, whereas in the 86 patients from group 2 the device was activated 6 months later. Serum creatinine and urine albumin/creatinine ratio were collected at screening (before device activation), and at months 6 and 12. Multilevel statistical analyses were adjusted for various covariables. Serum creatinine increased from 78 to 84 μmol/L, and glomerular filtration rate decreased from 92 to 87 mL/min per 1.73 m2 in group 1 at month 6 (P,0.05). These values did not change any further after 12 months of therapy. Patients with highest glomerular filtration rate showed the greatest decrease in glomerular filtration. Group 2 showed the ...
Question - Having sinus pressure, headaches and stiff neck. Could this be just a bad sinus infection? . Ask a Doctor about diagnosis, treatment and medication for Sinusitis, Ask a General & Family Physician
We tested whether 6-week vagal stimulation (VS) treatment improved open-loop baroreflex function in rats after myocardial infarction (MI). The following three groups of Sprague-Dawley rats were examined: normal control (NC, n = 9), MI with no treatme
The need of a more precise identification of the pathologic process extent as well as of the fine elements of intracranial anatomic features is often experienced in diagnostic process and during many operations in the nose, sinus, orbit and base of the skull region. In two case reports, the methods used in diagnostic work-up and surgical therapy in the nose and paranasal sinus region are described. Besides baseline x-ray, multislice computed tomography and magnetic resonance imaging scans, the techniques of operative field per viam imaging by use of rapid prototyping model, virtual endoscopy, and patient head 3D-imaging (3D-Doctor) were employed with differential coloration of all substantial head tissues (different tissues visualized in different colors), their anatomic inter-relations, and the extent of pathologic tissue within the operative field. This approach has not yet been used as a standard preoperative or intraoperative procedure in otorhinolaryngology. In this way, we tried to ...
EXPERIMENTAL FACTS. There exist several experimental methods of producing persistent arterial hypertension: (1) section of the cardio-aortic and carotid sinus "moderator nerves"1-3; (2) impairment of the cerebral blood flow through either intracranial injection of kaolin suspension4 or ligation of most of the vessels which supply the brain circulation5; (3) impairment of the renal blood flow6, 7; (4) repeated intramuscular injections of "hypertonin," which is obtained through ultra-filtration of the serum of hypertensive patients,8 and of various hormonal sterols.165. Elevation of blood pressure following section of the moderator nerves, although a phenomenon of outstanding theoretical interest, apparently has no bearing upon ...
Vertigo is NO fun at all. Its like being on a nightmarish ride you didnt ask to go on, and one you cant get off of.Sinusitis is usually blamed for vertigo,
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Approval for The ImageReady MR Conditional Pacing System. The device is indicated for the treatment of the following conditions:1) Symptomatic paroxysmal or permanent second- or third-degree AV block;2) Symptomatic bilateral bundle branch block;3) Symptomatic paroxysmal or transient sinus node dysfunction with or without associated AV conduction disorders (i.e., sinus bradycardia, sinus arrest, sinoatrial [SA] block);4) Bradycardia-tachycardia syndrome, to prevent symptomatic bradycardia or some forms of symptomatic tachyarrhythmias; and5) Neurovascular (vaso-vagal) syndromes or hypersensitive carotid sinus syndromes.Adaptive-rate pacing is indicated for patients exhibiting chronotropic incompetence and who may benefit from increased pacing rates concurrent with increases in minute ventilation and/or level of physical activity.Dual-chamber and atrial tracking modes are also indicated for patients who may benefit from maintenance of AV synchrony.Dual chamber modes are specifically indicated for ...
The isolated canine spleen was perfused at constant flow with continuous recording of splenic arterial perfusion pressure (SAPP) and spleen weight. Intra-arterial injections of the thromboxane A2 (TXA2) mimetic U46619 caused dose-related increases in splenic arterial perfusion pressure (SAPP) of short duration (ED50 0.31 nmol). There were very small changes in spleen weight accompanying any of the vasoconstrictor responses to U46619. The stable analogue of prostacyclin, iloprost, caused dose-dependent reductions in SAPP (ED50 1.3 nmol) indicating vasodilatation. There were no changes in spleen weight to any doses of iloprost indicating a lack of action on capsular smooth muscle. Similarly, the nitric oxide (NO) mimetic sodium nitroprusside caused dose-related reductions in SAPP of short duration (ED50 5.8 nmol). No changes in spleen weight accompanied splenic vasodilator responses to any dose of sodium nitroprusside (SNP). The results indicate the potential actions and intrinsic potency of three ...
Systems and methods provide baroreflex activation to treat or reduce pain and/or to cause or enhance sedation or sleep. Methods involve activating the baroreflex system to provide pain reduction, sedation, improved sleep or some combination thereof. Systems include at least one baroreflex activation device, at least one sensor for sensing physiological activity of the patient, and a processor coupled with the baroreflex activation device(s) and the sensor(s) for processing sensed data received from the sensor and for activating the baroreflex activation device. In some embodiments, the system is fully implantable within a patient, such as in an intravascular, extravascular or intramural location.
The need of a more precise identification of the pathologic process extent as well as of the fine elements of intracranial anatomic features is often experienced in diagnostic process and during many operations in the nose, sinus, orbit and base of the skull region. In two case reports, the methods used in diagnostic work-up and surgical therapy in the nose and paranasal sinus region are described. Besides baseline x-ray, multislice computed tomography and magnetic resonance imaging scans, the techniques of operative field per viam imaging by use of rapid prototyping model, virtual endoscopy, and patient head 3D-imaging (3D-Doctor) were employed with differential coloration of all substantial head tissues (different tissues visualized in different colors), their anatomic inter-relations, and the extent of pathologic tissue within the operative field. This approach has not yet been used as a standard preoperative or intraoperative procedure in otorhinolaryngology. In this way, we tried to ...
An increase in blood pressure will stretch carotid sinus and aortic arch ,which in turn will cause stretching or spreading of nerve endings ,which will increase influx of the sodium ions . Ultimately increase in depolarisation wave will cause stimulation of NTS (Even decrease in depolarisation wave will stimulate NTS ,which happens during decrease in blood pressure).Now as we know there is increase in blood pressure , NTS-our main character in this process will control these 3 centres to control blood pressure. Lets see what it do to these three centres present in medulla oblongata ...
An apparatus comprises a physiologic sensing circuit and a control circuit. The physiologic sensing circuit is configured to sense an electrical respiration signal representative of respiration of a subject. The control circuit includes a respiration monitor circuit and a therapy circuit. The respiration monitor circuit is configured to extract a respiration parameter from the respiration signal and detect that a value of the respiration parameter is outside of a target value range for the respiration parameter. The therapy circuit is configured to deliver neural stimulation to the carotid sinus of the subject to stimulate respiration and to adjust respiration to maintain the value of the respiration parameter within the target value range.
He hit him in the carotid sinus complex, essential to the normal function of the respiratory center and the center of heart rhythm. This in turn leads to su...
PJ Counihan, GA Haywood, AC ODonoghue, WJ McKenna; Abnormal Baroreceptor Sensitivity in Hypertrophic Cardiomyopathy. Clin Sci (Lond) 1 October 1990; 79 (s23): 13P. doi: https://doi.org/10.1042/cs079013Pb. Download citation file:. ...
A sinus infections, or sinusitis, might be caused by bacterial, fungal or viral infections, and individuals with asthma or allergies are more susceptible to infection than others. Common symptoms of a sinus infection include sinus pressure, headaches, nasal pain, congestion, nasal discharge, cough and fever. Treatments for sinus infections usually involve medications and home remedies to both relieve symptoms and treat the underlying cause.Home TipsDry air can worsen sinus-infection symptoms. Keep the air in your home from becoming too dry by using a humidifier. This is particularly helpful during dry, cold winter months. Additionally, hol...
If you dread allergy season, then you know what its like to suffer from itchy skin, red eyes, a runny nose, sneezing, sinus pressure, and headaches. Likewise, you may react to certain foods with hives, headaches, nasal congestion, skin problems, a racing heart, or irritability. What is the common denominator in both scenarios? Histamines. While…. ...
Earlier, Netanyahu checked into Haderas Hillel Yaffe Hospital complaining of headaches and sinus pressure, and was released two hours later. Jerusalem ...
Spontaneous internal carotid artery (ICA) dissection (sICAD) results from an intimal tear located around the distal carotid sinus. The mechanisms causing the tear are unknown. This case-control study tested the hypotheses that head movements increase the wall stress in the cervical ICA and that the stress increase is greater in patients with sICAD than in controls. Five patients with unilateral, recanalized, left sICAD and five matched controls were investigated before and after maximal head rotation to the left and neck hyperextension after 45° head rotation to the left. The anatomy of the extracranial carotid arteries was assessed by magnetic resonance imaging and used to create finite element models of the right ICA. Wall stress increased after head movements. Increases above the 80th and 90th percentile were located at the intimal side of the artery wall from 7.4 mm below to 10 mm above the cranial edge of the carotid sinus, i.e., at the same location as histologically confirmed tears in ...
TY - JOUR. T1 - Peripheral chemoreceptor inputs to medullary inspiratory and postinspiratory neurons of cats. AU - Lawson, Edward E.. AU - Richter, Diethelm W.. AU - Ballantyne, David. AU - Lalley, Peter M.. AU - Bischoff, Annemarie. AU - Kühner, Anita. PY - 1989/9/1. Y1 - 1989/9/1. N2 - The effect of peripheral chemoreceptor activation on inspiratory and postinspiratory medullary neurons was investigated using intracellular recording techniques. Peripheral chemoreceptors were activated by injecting CO2 saturated 1 N bicarbonate solution into the lingual artery or by electrically stimulating the carotid sinus nerve. Injections of 20-300 μl bicarbonate solution evoked changes in respiratory frequency and in peak phrenic nerve discharge. The membrane potential of inspiratory alpha neurons, whether bulbospinal or not and independent of their anatomic location, was decreased during inspiration. A sequence of compound excitatory and inhibitory effects were observed when the stimulus was given ...
Several years went by and we moved farther North where carpets are more commonly used than in the Southwest and I began to once again have "cold" symptoms. At least thats what we thought at first. Since I was hardly using cows milk and had resumed the allergy injections my wifeand I wondered, what could the cause ofthe post nasal drip, etc.,be this time. So I went back to an allergy specialist in our new area.After doing some testinghe foundI was very allergic to house dust.In the process of being given the allergy tests I found that not all house dustiscreated equal. Some dusts contain large amounts of dust mite droppings. This kind ofmites thrive in a humid and warm environment, like the one produced by the human body while lying in bed,where the miteseat mostly microscopic particles of human skin that rubs off there and on the carpet. The testsdid showI was very allergic to that kind of house dust. Thereupon I was given minute instructions by my doctoron how to shield my ...
B. False. Answers: Circulation. 1. A. True. The blood supply to the heart, efficiency of its muscle contractions, changes in rate and rhythm and increased work load all result from diving. Such stresses can be tolerated by a healthy heart, but can cause a heart attack in those with coronary problems. A person with any heart disorder should not dive unless cleared by both a cardiologist and a diving physician.. 2. B. False. The blood carries nearly as much oxygen as it can at all times. The change that takes place with exercise is in the circulation of the blood, which is increased to get oxygen to and waste products from tissues more quickly. Increased oxygen partial pressure while diving does allow more oxygen to be carried dissolved in the blood, but the benefit of this is offset by other cardiovascular changes.. 3. B. False. The carotid sinuses, located at the bifurcation of the arteries on each side of the neck, are sensors for blood pressure and provide information to the brain to control ...
We observed earlier that central alpha-2 adrenoceptor stimulation in mice greatly augments parasympathetic tone. To test the effects in humans, we assessed autonomic vasomotor tone and baroreflex regulation in 9 normal young adults on 2 occasions, on
What is the difference between Sinus Arrest and Sinus Block? Sinus arrest and sinus block are two conditions due to the dysfunction of the SA node. Sinus arrest
I am currently posting this from a river side view at KSB room 419. I started having sinus pressure and a headache on Wednesday evening. Things continued to get worse and I had a low grade temp all day and night Thursday. When I called Cleveland Friday morning they said to go to the ER. So when I got there and had blood test run, CT scan of chest and sinuses, influenza swab, and strep throat swab. The ER Doctor said that the CT results showed pneumonia and a sinus infection. I was admitted and put on 2 IV antibiotics and breathing treatments and 2 breathing appliances to help open up the passages. Not a good way to start my year off, but I have much to be thankful for through it all! God is still Great and has brought me through another test. Theres a song thats been going thru my head today and the chorus goes, "I know that I can make it. I know that I can stand. No matter what may come my way my life is in His hands. God is so good to me! Im so glad that my life Is in His hands." And now m ...
CLICK HERE FOR A FREE CALL If you dread allergy season, then you know what its like to suffer from itchy skin, red eyes, a runny nose, sneezing, sinus pressure, and headaches. Likewise, you may react to certain foods with hives, headaches, nasal congestion, skin problems, a racing heart, or irritability. What is the common [...]. ...
I get horrible migraines, sinus pressure and allergies when a storm is coming. I dont even need to look at the weather. I can tell when it is going to rain or snow just by how I feel. My father was the same way (doesnt have lyme), but all sorts of things can throw us off and weather is one of them. I live in Mass so unless I move to Arizona where or someplace where the weather stays the same, I just have to deal with it the best I can, but I really hate it ...
In hypertension baroreceptor-mediated modulation of heart rate is impaired, resulting in a decreased vagal control. Reactive oxygen species produced locally in the vasculature decrease baroreceptor sensitivity. Folic acid has antioxidant properties. Therefore, the aim of this study was to test whether folic acid improves baroreceptor function in hypertension. Twenty-one male patients with hypertension not taking any drugs for 2 weeks participated in the study and were randomized to folic acid 5 mg or matching placebo. Cardiac and vascular sympathetic baroreceptor functions were tested before and after a single dose of folic acid or placebo with two different methods: the alpha-coefficient method and the phenylephrine (PE) and sodium nitroprusside (SNP) bolus method. In the folic acid group both methods showed significantly improved cardiac and vascular sympathetic baroreceptor sensitivity compared with placebo. This study provides evidence that folic acid improves cardiac and vascular ...
... is a spontaneous, asymptomatic collapse of the maxillary sinus and orbital floor associated with negative sinus pressures. It can cause painless facial asymmetry, diplopia and enophthalmos . Usually the diagnosis is suspected clinically, and it can be confirmed radiologically by characteristic imaging features that include maxillary sinus outlet obstruction, sinus opacification, and sinus volume loss caused by inward retraction of the sinus walls. Treatment is surgical involving making an outlet for mucous drainage from the obstructed sinus. References Illner A, Davidson HC, Harnsberger HR, Hoffman J (2002).
TY - JOUR. T1 - Excitatory inputs to the RVLM in the context of the baroreceptor reflex. AU - Sved, Alan F.. AU - Ito, Satoru. AU - Madden, Christopher (Chris). AU - Stocker, Sean D.. AU - Yajima, Yoshiharu. PY - 2001. Y1 - 2001. N2 - The central neural circuit mediating baroreceptor control of sympathetic vasomotor outflow involves an excitatory projection from arterial baroreceptors to nucleus tractus solitarius, an excitatory projection from nucleus tractus solitarius to the caudal ventrolateral medulla, an inhibitory projection from the caudal ventrolateral medulla to the rostral ventrolateral medulla (RVLM), and an excitatory projection from the RVLM to sympathetic preganglionic neurons in the spinal cord. For this circuit to be operational, the relevant neurons in the RVLM must be tonically active. Indeed, numerous studies have demonstrated that RVLM vasomotor neurons are tonically active; however, little is known regarding the nature of the tonic excitatory drive to these neurons. We ...
Define sinus sigmoideus. sinus sigmoideus synonyms, sinus sigmoideus pronunciation, sinus sigmoideus translation, English dictionary definition of sinus sigmoideus. Noun 1. sinus sigmoideus - an S-shaped dural sinus on the temporal and occipital bones sigmoid sinus venous sinus, sinus - a wide channel containing blood;...

Sick Sinus Syndrome (and Carotid Sinus Syndrome) | Springer for Research & DevelopmentSick Sinus Syndrome (and Carotid Sinus Syndrome) | Springer for Research & Development

The sick sinus syndrome is a disease of the sinus node and occurs in middle-aged and older patients, with some exceptions. The ... Carotid sinus syndrome and falls in older adults. Am J Geriatr Cardiol 2001;10:97-9PubMedCrossRefGoogle Scholar ... the carotid sinus syndrome, which is different from the sick sinus syndrome, is briefly discussed. ... The sick sinus syndrome is a disease of the sinus node and occurs in middle-aged and older patients, with some exceptions. The ...
more infohttps://rd.springer.com/chapter/10.1007/978-3-662-10315-9_23

Carotid sinus reflex synonyms, Carotid sinus reflex antonyms - FreeThesaurus.comCarotid sinus reflex synonyms, Carotid sinus reflex antonyms - FreeThesaurus.com

Antonyms for Carotid sinus reflex. 26 synonyms for reflex: automatic, spontaneous, instinctive, involuntary, impulsive, knee- ... jerk, unthinking, automatic, impulsive, instinctive, involuntary.... What are synonyms for Carotid sinus reflex? ... Synonyms for Carotid sinus reflex in Free Thesaurus. ... Carotid Sinus Nerve Discharge. *Carotid Sinus Nerve Transection ... Carotid sinus reflex synonyms, Carotid sinus reflex antonyms - FreeThesaurus.com https://www.freethesaurus.com/Carotid+sinus+ ...
more infohttp://www.freethesaurus.com/Carotid+sinus+reflex

Faculty Collaboration Database - Interaction of right and left carotid sinus baroreflexes in the dog.  Am J Physiol 1986 Jan...Faculty Collaboration Database - Interaction of right and left carotid sinus baroreflexes in the dog. Am J Physiol 1986 Jan...

Right carotid sinus gain was found to be 0.628 +/- 0.058 at a left carotid sinus pressure of 50 mmHg and 0.148 +/- 0.027 when ... Carotid sinus reflex interactions were studied in 10 dogs anesthetized with pentobarbital sodium. The right and left carotid ... left carotid sinus pressure was 200 mmHg. Similar results were found for left carotid sinus gain. Suppression was also found ... when carotid sinus pressure was changed on one side were strongly influenced by pressure in the contralateral carotid sinus (P ...
more infohttps://fcd.mcw.edu/?module=search&func=showPublication&id=9189

Carotid Body Tumours: A ReviewCarotid Body Tumours: A Review

... mostly benign tumour arising from the paraganglia of carotid body; hence, the name (carotid paraganglioma). The high ... Carotid body tumour (CBT); formerly known as chemodectoma is a rare, highly vascular, ... The carotid body is a small structure weighing 12 mg located in the adventitia of carotid artery bifurcation acting as a ... Carotid Body, Carotid Sinus, Paraganglioma, Neuroendocrine Tumours, Carotid Body Tumours, Review Cite this paper ...
more infohttps://scirp.org/journal/paperinformation.aspx?paperid=54805

Carotid sinus - definition of carotid sinus by The Free DictionaryCarotid sinus - definition of carotid sinus by The Free Dictionary

carotid sinus synonyms, carotid sinus pronunciation, carotid sinus translation, English dictionary definition of carotid sinus ... n. A dilated area located at the bifurcations of the carotid arteries and containing numerous baroreceptors that function in ... Related to carotid sinus: carotid artery, Baroreceptors, carotid sinus massage, Carotid sinus reflex ... Carotid sinus - definition of carotid sinus by The Free Dictionary https://www.thefreedictionary.com/carotid+sinus ...
more infohttp://www.thefreedictionary.com/carotid+sinus

Carotid Sinus Massage in the Echocardiography Laboratory.Carotid Sinus Massage in the Echocardiography Laboratory.

In this article, we discuss the use of carotid sinus mas ... In this article, we discuss the use of carotid sinus massage ( ... 24607007 - Tension to passively cinch the mitral annulus through coronary sinus access: an ex vivo.... 9403167 - Mechanisms and ...
more infohttp://www.biomedsearch.com/nih/Carotid-Sinus-Massage-in-Echocardiography/24355057.html

Mortality in carotid sinus hypersensitivity: a cohort study | BMJ OpenMortality in carotid sinus hypersensitivity: a cohort study | BMJ Open

2011, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions. This is an open-access article distributed under the terms of the Creative Commons Attribution Non-commercial License, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited, the use is non commercial and is otherwise in compliance with the license. See: http://creativecommons.org/licenses/by-nc/2.0/ and http://creativecommons.org/licenses/by-nc/2.0/legalcode. ...
more infohttps://bmjopen.bmj.com/content/1/1/e000020.info

Carotid sinus baroreflex | definition of Carotid sinus baroreflex by Medical dictionaryCarotid sinus baroreflex | definition of Carotid sinus baroreflex by Medical dictionary

What is Carotid sinus baroreflex? Meaning of Carotid sinus baroreflex medical term. What does Carotid sinus baroreflex mean? ... Looking for online definition of Carotid sinus baroreflex in the Medical Dictionary? Carotid sinus baroreflex explanation free ... Related to Carotid sinus baroreflex: Carotid sinus reflex, Carotid sinus baroreceptor stimulation, Carotid sinus stimulation ... Synonym(s): sinus caroticus [TA], carotid bulb. carotid sinus. n.. A dilated area located at the bifurcations of the carotid ...
more infohttp://medical-dictionary.thefreedictionary.com/Carotid+sinus+baroreflex

Carotid sinus reflex | definition of carotid sinus reflex by Medical dictionaryCarotid sinus reflex | definition of carotid sinus reflex by Medical dictionary

What is carotid sinus reflex? Meaning of carotid sinus reflex medical term. What does carotid sinus reflex mean? ... Looking for online definition of carotid sinus reflex in the Medical Dictionary? carotid sinus reflex explanation free. ... carotid sinus reflex. Also found in: Dictionary, Thesaurus, Legal, Encyclopedia.. Related to carotid sinus reflex: gag reflex, ... carotid sinus. a dilatation of the proximal portion of the internal carotid or distal portion of the common carotid artery, ...
more infohttp://medical-dictionary.thefreedictionary.com/carotid+sinus+reflex

Inhibition of the Carotid Sinus Reflex by Stimulation of the Inferior Olive | ScienceInhibition of the Carotid Sinus Reflex by Stimulation of the Inferior Olive | Science

Inhibition of the Carotid Sinus Reflex by Stimulation of the Inferior Olive ... Inhibition of the Carotid Sinus Reflex by Stimulation of the Inferior Olive ... Inhibition of the Carotid Sinus Reflex by Stimulation of the Inferior Olive ... Inhibition of the Carotid Sinus Reflex by Stimulation of the Inferior Olive ...
more infohttp://science.sciencemag.org/content/154/3749/674

Carotid sinus - WikipediaCarotid sinus - Wikipedia

Massage of the carotid sinus, carotid sinus massage is used to diagnose carotid sinus syncope and is sometimes useful for ... a condition known as carotid sinus hypersensitivity, carotid sinus syndrome or carotid sinus syncope, in which manual ... The carotid sinus extends from the bifurcation to the "true" internal carotid artery. The carotid sinus is sensitive to ... Carotid sinus reflex death - a theory and its history. URL last accessed February 28, 2006. "Carotid Sinus strike/slap as an ...
more infohttps://en.wikipedia.org/wiki/Carotid_sinus

Carotid Sinus | Article about Carotid Sinus by The Free DictionaryCarotid Sinus | Article about Carotid Sinus by The Free Dictionary

Find out information about Carotid Sinus. An enlargement at the bifurcation of each carotid artery that is supplied with ... Related to Carotid Sinus: carotid artery, Baroreceptors, carotid sinus massage, Carotid sinus reflex ... Carotid body tumor presenting with carotid sinus syndrome.. A Rare Case of Carotid Body Tumor Presenting with Internal Carotid ... Carotid Sinus , Article about Carotid Sinus by The Free Dictionary https://encyclopedia2.thefreedictionary.com/Carotid+Sinus ...
more infohttps://encyclopedia2.thefreedictionary.com/Carotid+Sinus

CAROTID SINUS REFLEX CHANGES PRODUCED BY DIGITALIS | Journal of Pharmacology and Experimental TherapeuticsCAROTID SINUS REFLEX CHANGES PRODUCED BY DIGITALIS | Journal of Pharmacology and Experimental Therapeutics

... was also found to activate the carotid sinus reflexes as an increase in sinus nerve activity occurred which coincided with ... CAROTID SINUS REFLEX CHANGES PRODUCED BY DIGITALIS Message Subject (Your Name) has forwarded a page to you from Journal of ... CAROTID SINUS REFLEX CHANGES PRODUCED BY DIGITALIS. JOHN A. QUEST and RICHARD A. GILLIS ... CAROTID SINUS REFLEX CHANGES PRODUCED BY DIGITALIS. JOHN A. QUEST and RICHARD A. GILLIS ...
more infohttp://jpet.aspetjournals.org/content/177/3/650

Glossopharyngeal and Limited Vagal Neurectomy for Cancer-Related Carotid Sinus SyncopeGlossopharyngeal and Limited Vagal Neurectomy for Cancer-Related Carotid Sinus Syncope

Patel A K, Yap V U, Fields J, Thomsen J H. Carotid sinus syncope induced by malignant tumors in the neck. Arch Intern Med. 1979 ... Glossopharyngeal and Limited Vagal Neurectomy for Cancer-Related Carotid Sinus Syncope. Harrison W. Lin, M.D.,1,2 Michael B. ... Frank J I, Ropper A H, Zuniga G. Vasodepressor carotid sinus syncope associated with a neck mass. Neurology. 1992;42(6):1194- ... Muntz H R, Smith P G. Carotid sinus hypersensitivity: a cause of syncope in patients with tumors of the head and neck. ...
more infohttp://pubmedcentralcanada.ca/pmcc/articles/PMC2765699/

BestBets: Comparing Valsalva manoeuvre with carotid sinus massage in adults with supraventricular tachycardiaBestBets: Comparing Valsalva manoeuvre with carotid sinus massage in adults with supraventricular tachycardia

Restoring PSVT to sinus rhythm. Valsalva 16.7% vs Carotid sinus massage 0%. Operator bias, small numbers, lack of blinding, ... Valsalva 12.0% vs carotid sinus massage 6.3%; p. Total instances of PSVT sucessfully treated by vagal manoeuvres without ... Right and left carotid sinus massage and the diving reflex were considerably less effective than the valsalva manoeuvre. ... overal sucess rate: Valsalva 18.0% vs Carotid sinus massage 11.8%; p=NS; CI [-2.8% to 20.7%]. Outcomes were not assessed blind ...
more infohttps://bestbets.org/bets/bet.php?id=930

Bioelectronic modulation of carotid sinus nerve activity in the rat: a potential therapeutic approach for type 2 diabetes |...Bioelectronic modulation of carotid sinus nerve activity in the rat: a potential therapeutic approach for type 2 diabetes |...

Carotid body Carotid sinus nerve Glucose tolerance Insulin resistance KHFAC modulation Neuromodulation Type 2 diabetes ... Bioelectronic modulation of carotid sinus nerve activity in the rat: a potential therapeutic approach for type 2 diabetes. ... Carotid sinus nerve (CSN) denervation has been shown to improve glucose homeostasis in insulin-resistant and glucose-intolerant ... the carotid sinus nerve (CSN), restores insulin sensitivity and glucose tolerance in high-energy-fed animal models of insulin ...
more infohttps://link.springer.com/article/10.1007/s00125-017-4533-7

Branch of glossopharyngeal nerve to carotid sinus - WikipediaBranch of glossopharyngeal nerve to carotid sinus - Wikipedia

... and then divides in the angle of the bifurcation of the common carotid artery to innervate the carotid body and carotid sinus. ... that innervates the carotid sinus and the carotid body. It is a branch of the glossopharyngeal nerve that runs downwards, ... It carries impulses from the baroreceptors in the carotid sinus to the vasomotor center in the brainstem (to help maintain a ... The branch of glossopharyngeal nerve to the carotid sinus (Herings nerve) is a small nerve in the neck, ...
more infohttps://en.wikipedia.org/wiki/Branch_of_glossopharyngeal_nerve_to_carotid_sinus

Carotid Sinus Reflex Control of Renin Release in Hypertensive Subjects with High Renin Secretion | Clinical ScienceCarotid Sinus Reflex Control of Renin Release in Hypertensive Subjects with High Renin Secretion | Clinical Science

Carotid Sinus Reflex Control of Renin Release in Hypertensive Subjects with High Renin Secretion. G. Mancia, A. Ferrari, G. ... Carotid Sinus Reflex Control of Renin Release in Hypertensive Subjects with High Renin Secretion ... Carotid Sinus Reflex Control of Renin Release in Hypertensive Subjects with High Renin Secretion ... Carotid Sinus Reflex Control of Renin Release in Hypertensive Subjects with High Renin Secretion ...
more infohttp://www.clinsci.org/content/61/5/505

Branch of glossopharyngeal nerve to carotid sinusBranch of glossopharyngeal nerve to carotid sinus

... Hypoglossal nerve, cervical plexus, and their ... Branch of glossopharyngeal nerve to carotid sinus Nerve: ... The branch of the glossopharyngeal nerve to the carotid sinus ... It uses material from the Wikipedia article "Branch_of_glossopharyngeal_nerve_to_carotid_sinus". A list of authors is available ... nucleus ambiguus • ganglia (superior, petrous) • tympanic (tympanic plexus, lesser petrosal) • carotid sinus • pharyngeal ...
more infohttps://www.bionity.com/en/encyclopedia/Branch_of_glossopharyngeal_nerve_to_carotid_sinus.html

Role of Chemoreceptor Activation in Hemodynamic Responses to Electrical Stimulation of the Carotid Sinus in Conscious...Role of Chemoreceptor Activation in Hemodynamic Responses to Electrical Stimulation of the Carotid Sinus in Conscious...

... carotid body artery; CC, carotid canal; CCA, common carotid artery; CS, carotid sinus; CSN, carotid sinus nerve; ECA, external ... 18 was adapted to stimulate the carotid sinus. Thus, simultaneous electric stimulation of the carotid sinus and carotid sinus ... Moreover, combined electric stimulation of the carotid sinus and the carotid sinus nerve in the absence of the carotid ... of the carotid sinus and carotid sinus nerve in conscious rats during 20 s. BARO-X indicates denervated carotid baroreceptor; ...
more infohttp://hyper.ahajournals.org/content/66/3/598

MANUAL COMPRESSION OF THE CAROTID VESSELS, CAROTID SINUS HYPERSENSITIVITY AND CAROTID ARTERY OCCLUSIONS* | Annals of Internal...MANUAL COMPRESSION OF THE CAROTID VESSELS, CAROTID SINUS HYPERSENSITIVITY AND CAROTID ARTERY OCCLUSIONS* | Annals of Internal...

MANUAL COMPRESSION OF THE CAROTID VESSELS, CAROTID SINUS HYPERSENSITIVITY AND CAROTID ARTERY OCCLUSIONS1 ALLEN SILVERSTEIN, M.D ... MANUAL COMPRESSION OF THE CAROTID VESSELS, CAROTID SINUS HYPERSENSITIVITY AND CAROTID ARTERY OCCLUSIONS1. Ann Intern Med. 1960; ... BUCKLING OF THE CAROTID ARTERY DEMONSTRATED BY ANGIOCARDIOGRAPHY1 Annals of Internal Medicine; 44 (5): 1003-1007 ... "Subclavian Steal Syndrome" with Reversal of Blood Flow in the Right Carotid Artery Annals of Internal Medicine; 64 (1): 142-144 ...
more infohttps://annals.org/aim/article-abstract/677400/manual-compression-carotid-vessels-carotid-sinus-hypersensitivity-carotid-artery-occlusions

Prolonged Carotid Sinus Reflex Is a Risk Factor for Contrast-Induced Nephropathy following Carotid Artery Stenting | American...Prolonged Carotid Sinus Reflex Is a Risk Factor for Contrast-Induced Nephropathy following Carotid Artery Stenting | American...

Prolonged Carotid Sinus Reflex Is a Risk Factor for Contrast-Induced Nephropathy following Carotid Artery Stenting. T. Kato, H ... Prolonged Carotid Sinus Reflex Is a Risk Factor for Contrast-Induced Nephropathy following Carotid Artery Stenting ... Carotid sinus reactions during carotid artery stenting: predictors, incidence, and influence on clinical outcome. Catheter ... Prolonged Carotid Sinus Reflex Is a Risk Factor for Contrast-Induced Nephropathy following Carotid Artery Stenting ...
more infohttp://www.ajnr.org/content/32/3/441.full

Unexplained syncope-is screening for carotid sinus hypersensitivity indicated in all patients aged |40 years? | Journal of...Unexplained syncope-is screening for carotid sinus hypersensitivity indicated in all patients aged |40 years? | Journal of...

Methods: Carotid sinus massage (CSM) was performed both supine and during 60° head-up tilt. Beat-to-beat blood pressure, heart ... Objective: To determine the frequency, age distribution and clinical presentation of carotid sinus hypersensitivity (CSH) among ... Unexplained syncope-is screening for carotid sinus hypersensitivity indicated in all patients aged ,40 years? ... Unexplained syncope-is screening for carotid sinus hypersensitivity indicated in all patients aged ,40 years? ...
more infohttp://jnnp.bmj.com/content/77/11/1267

Carotid sinus hypersensitivity associated with focal alpha-synucleinopathy of the autonomic nervous system. - Semantic ScholarCarotid sinus hypersensitivity associated with focal alpha-synucleinopathy of the autonomic nervous system. - Semantic Scholar

She exhibited a cardioinhibitory carotid sinus hypersensitivity after right carotid sinus massage (CSM), but without evidence ... She exhibited a cardioinhibitory carotid sinus hypersensitivity after right carotid sinus massage (CSM), but without evidence ... Mayer wave activity in vasodepressor carotid sinus hypersensitivity.. *Ciarán Finucane, Gerard Boyle, Chie Wei Fan, Dymphna ... Carotid sinus syndrome secondary to head and neck malignancy : Case report and literature review. *Angela M. Hong, Lynne A ...
more infohttps://www.semanticscholar.org/paper/Carotid-sinus-hypersensitivity-associated-with-of-Polvikoski-Kalaria/4c87ceadbca2643d8fd8f1e7a54c9d7a81eca605

The Role of Vagus and Carotid Sinus Nerves on Systemic and Renal Responses to Somatic Afferent Stimulation in the Rat |...The Role of Vagus and Carotid Sinus Nerves on Systemic and Renal Responses to Somatic Afferent Stimulation in the Rat |...

The Role of Vagus and Carotid Sinus Nerves on Systemic and Renal Responses to Somatic Afferent Stimulation in the Rat. G Davis ... The Role of Vagus and Carotid Sinus Nerves on Systemic and Renal Responses to Somatic Afferent Stimulation in the Rat ... The Role of Vagus and Carotid Sinus Nerves on Systemic and Renal Responses to Somatic Afferent Stimulation in the Rat ... The Role of Vagus and Carotid Sinus Nerves on Systemic and Renal Responses to Somatic Afferent Stimulation in the Rat ...
more infohttp://www.clinsci.org/content/75/s19/25P.4
  • An additional inhibitory summation between the right and left carotid sinuses was found such that simultaneous excitation of both receptors resulted in a smaller reflex response than did the sum of individual responses. (mcw.edu)
  • Pressure in the right and left carotid sinuses were independently varied, and the resulting steady-state reflex changes in arterial pressure, heart rate, respiratory frequency, tidal volume, and total ventilation were measured. (mcw.edu)
  • Electrophysiologic characteristics of the atrium in sinus node dysfunction: atrial refractoriness and conduction. (springer.com)
  • Assessment and management of sinus node dysfunction. (springer.com)
  • Indications for electrophysiologic testing in the diagnosis and assessment of sinus node dysfunction. (springer.com)
  • The most probable predominant etiology is a degenerative process of the sinus node with frequent involvement of the AV node. (springer.com)
  • Interaction of right and left carotid sinus baroreflexes in the dog. (mcw.edu)
  • Bertrand E, Le Gallais D, N'Dori R. The Flack test: a test exploring the sinus function in athletes. (springer.com)
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