A measurement of the thickness of the carotid artery walls. It is measured by B-mode ULTRASONOGRAPHY and is used as a surrogate marker for ATHEROSCLEROSIS.
The innermost layer of an artery or vein, made up of one layer of endothelial cells and supported by an internal elastic lamina.
The middle layer of blood vessel walls, composed principally of thin, cylindrical, smooth muscle cells and elastic tissue. It accounts for the bulk of the wall of most arteries. The smooth muscle cells are arranged in circular layers around the vessel, and the thickness of the coat varies with the size of the vessel.
Either of the two principal arteries on both sides of the neck that supply blood to the head and neck; each divides into two branches, the internal carotid artery and the external carotid artery.
The two principal arteries supplying the structures of the head and neck. They ascend in the neck, one on each side, and at the level of the upper border of the thyroid cartilage, each divides into two branches, the external (CAROTID ARTERY, EXTERNAL) and internal (CAROTID ARTERY, INTERNAL) carotid arteries.
Pathological conditions involving the CAROTID ARTERIES, including the common, internal, and external carotid arteries. ATHEROSCLEROSIS and TRAUMA are relatively frequent causes of carotid artery pathology.
A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3)
Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.
The excision of the thickened, atheromatous tunica intima of a carotid artery.
The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.
Branch of the common carotid artery which supplies the anterior part of the brain, the eye and its appendages, the forehead and nose.
Damages to the CAROTID ARTERIES caused either by blunt force or penetrating trauma, such as CRANIOCEREBRAL TRAUMA; THORACIC INJURIES; and NECK INJURIES. Damaged carotid arteries can lead to CAROTID ARTERY THROMBOSIS; CAROTID-CAVERNOUS SINUS FISTULA; pseudoaneurysm formation; and INTERNAL CAROTID ARTERY DISSECTION. (From Am J Forensic Med Pathol 1997, 18:251; J Trauma 1994, 37:473)
Statistical models in which the value of a parameter for a given value of a factor is assumed to be equal to a + bx, where a and b are constants. The models predict a linear regression.
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
The main artery of the thigh, a continuation of the external iliac artery.
Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
A small cluster of chemoreceptive and supporting cells located near the bifurcation of the internal carotid artery. The carotid body, which is richly supplied with fenestrated capillaries, senses the pH, carbon dioxide, and oxygen concentrations in the blood and plays a crucial role in their homeostatic control.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Lesions formed within the walls of ARTERIES.
An indicator of body density as determined by the relationship of BODY WEIGHT to BODY HEIGHT. BMI=weight (kg)/height squared (m2). BMI correlates with body fat (ADIPOSE TISSUE). Their relationship varies with age and gender. For adults, BMI falls into these categories: below 18.5 (underweight); 18.5-24.9 (normal); 25.0-29.9 (overweight); 30.0 and above (obese). (National Center for Health Statistics, Centers for Disease Control and Prevention)
An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
A status with BODY WEIGHT that is grossly above the acceptable or desirable weight, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
The vessels carrying blood away from the heart.
The dilated portion of the common carotid artery at its bifurcation into external and internal carotids. It contains baroreceptors which, when stimulated, cause slowing of the heart, vasodilatation, and a fall in blood pressure.
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.
Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.
PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.
The nonstriated involuntary muscle tissue of blood vessels.
Branch of the common carotid artery which supplies the exterior of the head, the face, and the greater part of the neck.
The main trunk of the systemic arteries.
A generic term for fats and lipoids, the alcohol-ether-soluble constituents of protoplasm, which are insoluble in water. They comprise the fats, fatty oils, essential oils, waxes, phospholipids, glycolipids, sulfolipids, aminolipids, chromolipids (lipochromes), and fatty acids. (Grant & Hackh's Chemical Dictionary, 5th ed)
The new and thickened layer of scar tissue that forms on a PROSTHESIS, or as a result of vessel injury especially following ANGIOPLASTY or stent placement.
Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.
Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components.
Blood clot formation in any part of the CAROTID ARTERIES. This may produce CAROTID STENOSIS or occlusion of the vessel, leading to TRANSIENT ISCHEMIC ATTACK; CEREBRAL INFARCTION; or AMAUROSIS FUGAX.
Use of a balloon catheter for dilation of an occluded artery. It is used in treatment of arterial occlusive diseases, including renal artery stenosis and arterial occlusions in the leg. For the specific technique of BALLOON DILATION in coronary arteries, ANGIOPLASTY, BALLOON, CORONARY is available.
Pathologic deposition of calcium salts in tissues.
The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.
A strain of Rattus norvegicus with elevated blood pressure used as a model for studying hypertension and stroke.
General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).

Recombinant human interleukin-10 inhibits proliferation of vascular smooth muscle cells stimulated by advanced glycation end products and neointima hyperplasia after carotid injury in the rat. (1/431)

The purposes of this study was to determine the effects of recombinant human interleukin-10 (rhIL-10) on proliferation of vascular smooth muscle cells (VSMCs) stimulated by advanced glycation end products (AGE) and neointima hyperplasia after rat carotid arterial injury. Rat aortic VSMCs were cultured and treated with rhIL-10 or AGE respectively, and then co-treated with rhIL-10 and AGE. Proliferation of VSMCs was quantified by colormetric assay. Cell cycle analysis was performed by flow cytomertry. Sprague-Dawley rats were treated with recombinant human IL-10 (rhIL-10) for 3 d after carotid arteries injury. The ratio of neointima to media area at the site of arterial injury was measured 28 d after balloon injury. The p44/42 MAPK activity was evaluated by the immunoblotting technique using anti-p44/42 phospho-MAPK antibody. Compared to control, AGE stimulated VSMCs proliferation. rhIL-10 alone had no effect on VSMCs growth. With AGE stimulation, rhIL-10, at dose as low as 10 ng/ml, inhibited VSMCs growth (P<0.05). The cell number in G(0)/G(1) phase of AGE and rhIL-10 co-treatment group was higher than that of AGE treatment alone (P<0.01) by flow cytometry analysis. Compared with the control group of neointima hyperplasia in rats, the ratio of neointima to media area of recombinant human IL-10 group was reduced by 45% (P<0.01). The p44/42 MAPK activity was significantly enhanced by AGE. The AGE effects were opposed by rhIL-10. The anti-inflammatory cytokine rhIL-10 inhibits AGE-induced VSMCs proliferation. Recombinant human IL-10 also inhibited neointima hyperplasia after carotid artery injury in rats. The results suggest the possibility that recombinant human IL-10, as a potential therapeutic approach, prevents neointimal hyperplasia.  (+info)

Epidermal fatty-acid-binding protein: a new circulating biomarker associated with cardio-metabolic risk factors and carotid atherosclerosis. (2/431)

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Physical exercise, fitness and dietary pattern and their relationship with circadian blood pressure pattern, augmentation index and endothelial dysfunction biological markers: EVIDENT study protocol. (3/431)

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Medical decision-making system of ultrasound carotid artery intima-media thickness using neural networks. (4/431)

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The age correlation of the carotid intima-media thickness according to sex and side in asymptomatic subjects. (5/431)

PURPOSE: Reports concerning carotid intima-media thickness (CIMT) and linear correlation to age in healthy subjects did not distinguish the side and sex of the subjects. The purpose of this investigation attempts to clarify these issues. METHODS: 2402 asymptomatic persons, age 35-64, are separated into men's left (Lt) and right (Rt) and women's Lt and Rt carotid arteries for difference of CIMT between them and analysis of CIMT vs. age. RESULTS: There are significant difference between men's CIMT of Lt(CIMTML) vs Rt (CIMTMR), women's Lt(CIMTWL) vs. Rt (CIMTWR), Lt side CIMT of men vs women, and Rt side CIMT of men vs. women. The regression equation of CIMT vs. age for all four groups is determinated. CONCLUSION: We found an excellent linear correlation of CIMT to age and CIMT is significantly higher in men than women, so as higher in Lt than Rt. Further grouping of data into about 5-year period showed more clearly stepwise increasing of CIMT, so as the ratios of Lt CIMT different than Rt. CIMT study is served as highly efficient examination in therapy, prevention, clinic, or research survey about atherosclerosis and risk of stroke. Future study design concerning CIMT in separation groups of men and women, so as Lt and Rt is highly recommended.  (+info)

Atherogenic lipid profile and systolic blood pressure are associated with carotid artery intima-media thickness in children with Turner syndrome. (6/431)

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Polymorphic variation in choline transporter gene (CHT1) is associated with early, subclinical measures of carotid atherosclerosis in humans. (7/431)

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Real-time co-registration using novel ultrasound technology: ex vivo validation and in vivo applications. (8/431)

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The triple line pattern on carotid intima media thickness imaging and its relationship to cardiovascular risk factors in patients on lipid lowering therapy Tania A Singh,1 Todd C Villines,2 Allen J Taylor31Division of Cardiology, Medstar Georgetown University Hospital, 2Walter Reed National Military Medical Center, Bethesda, MD, 3Georgetown University School of Medicine, Washington, DC, USA Background: Carotid intima media thickness (CIMT) infrequently identifies a triple line pattern (TLP) in the visualization of the internal elastic lamina. We examined the prevalence and predictors of the TLP among a consecutive series of subjects enrolled in a CIMT clinical trial, and also the effects of lipid lowering therapy.Methods: Baseline CIMT studies of subjects with known heart disease, or high risk for heart disease, were evaluated from a single site of the Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol 6-HDL and LDL Treatment Strategies in Atherosclerosis trial (N
TY - JOUR. T1 - Carotid intima-media thickness among normoglycemia and normotension first-degree relatives of type 2 diabetes mellitus. AU - Purnamasari, Dyah. AU - Abdaly, Muhammad Syah. AU - Azizi, Mohamad Syahrir. AU - Wijaya, Ika Prasetya. AU - Nugroho, Pringgodigdo. PY - 2019/1/1. Y1 - 2019/1/1. N2 - Introduction: Theoretically, first-degree relatives (FDRs) of type 2 diabetes mellitus (T2DM) are predisposed to have earlier and more severe atherosclerosis than non-FDR due to hereditary insulin resistance. A previous study reported that atherosclerotic plaques were found in 45.2% of young adults FDR of T2DM, but the study did not include non-FDR as control group. The aim of this study was to compare subclinical atherosclerosis (carotid intima-media thickness, CIMT) between FDR of T2DM and non-FDR. Method: This was a cross-sectional study involving 16 FDR subjects and 16 age-sex matched non-FDR subjects, aged 19-40 years, with normal glucose tolerance and no hypertension. Collected data ...
TY - CONF. T1 - Use of Carotid Intima-Media Thickness and Plaque Volume to Predict Single or Multi-vessel Coronary Artery Disease.. AU - Owen, Kathryn. AU - Menown, Ian. AU - McLaughlin, James. PY - 2020/12/15. Y1 - 2020/12/15. N2 - INTRODUCTION Increased carotid intima-media thickness (cIMT) has been extensively evaluated as a marker of cardiovascular risk. However, there are only limited data correlating cIMT and other carotid measurements with the presence and anatomical severity of coronary artery disease (CAD).PROBLEMCurrently, the two gold-standard methods for diagnosing CAD are Invasive Coronary Angiography (ICA) and Computed Tomography Coronary Angiography(CTCA). With over 250,000 ICAs and 42, 340 CTCAs performed in the UK each year, at a cost of £2500 and £500 retrospectively, this is an enormous cost to the health service. ICA and CTCA both require radiation and in the case of the former, a day in hospital. Of those undergoing diagnostic angiograms, almost two-thirds do not have ...
TY - CONF. T1 - Use of Carotid Intima-Media Thickness and Plaque Volume to Predict Single or Multi-vessel Coronary Artery Disease.. AU - Owen, Kathryn. AU - Menown, Ian. AU - McLaughlin, James. PY - 2020/12/15. Y1 - 2020/12/15. N2 - INTRODUCTION Increased carotid intima-media thickness (cIMT) has been extensively evaluated as a marker of cardiovascular risk. However, there are only limited data correlating cIMT and other carotid measurements with the presence and anatomical severity of coronary artery disease (CAD).PROBLEMCurrently, the two gold-standard methods for diagnosing CAD are Invasive Coronary Angiography (ICA) and Computed Tomography Coronary Angiography(CTCA). With over 250,000 ICAs and 42, 340 CTCAs performed in the UK each year, at a cost of £2500 and £500 retrospectively, this is an enormous cost to the health service. ICA and CTCA both require radiation and in the case of the former, a day in hospital. Of those undergoing diagnostic angiograms, almost two-thirds do not have ...
Vascular morbidity and mortality due to cardiovascular disease (CVD) are high after ischemic stroke at a young age. Data on carotid intima-media thickness (cIMT) as marker of atherosclerosis are scarce for young stroke populations. In this prospective case-control study, we examined cIMT, the burden of vascular risk factors (RF) and their associations among young and middle-aged ischemic stroke patients and controls. We aimed to detect clinical and sub-clinical arterial disease. This study was conducted in 150 patients aged 15-60 years and 84 controls free of CVD. We related RF to ultrasonographic B-mode cIMT-measurements obtained from 12 standardized multiangle measurements in the common carotid artery (CCA), carotid bifurcation (BIF) and internal carotid artery (ICA). RF burden was higher among patients than among controls (p | 0.001). In multivariate analyses of all 234 participants, increased cIMT was associated with age in each carotid segment. Incident stroke was associated with increased ICA-IMT.
BACKGROUND: Carotid intima-media thickness (cIMT) is a widely accepted marker of subclinical atherosclerosis. To date, large-scale investigations of genetic determinants of cIMT are sparse. METHODS AND RESULTS: To identify cIMT-associated genes and genetic variants, a discovery analysis using the Illumina 200K CardioMetabochip was conducted in 3430 subjects with detailed ultrasonographic determinations of cIMT from the IMPROVE (Carotid Intima Media Thickness [IMT] and IMT-Progression as Predictors of Vascular Events in a High Risk European Population) study. Segment-specific IMT measurements of common carotid, bifurcation, and internal carotid arteries, and composite IMT variables considering the whole carotid tree (IMT(mean), IMT(max), and IMT(mean-max)), were analyzed. A replication stage investigating 42 single-nucleotide polymorphisms for association with common carotid IMT was undertaken in 5 independent European cohorts (total n=11,590). A locus on chromosome 16 (lead single-nucleotide
Carotid intima-media thickness (CIMT) is associated with an increased risk of cardiovascular disease. We studied whether CIMT predicts the prognosis of Asian patients with acute ST-elevation myocardial infarction (STEMI). A total of 345 patien
TY - JOUR. T1 - Growth of Carotid Intima-Media Thickness in Black and White Young Adults. AU - Hao, Guang. AU - Wang, Xiaoling. AU - Treiber, Frank A.. AU - Davis, Harry. AU - Leverett, Sharika. AU - Su, Shaoyong. AU - Kapuku, Gaston. PY - 2016/12. Y1 - 2016/12. N2 - Background--There are few longitudinal studies that have comprehensively examined the intima-media thickness (IMT) growth pattern and its determinants among racial population groups. Methods and Results--Mean and maximum IMT were measured by B-mode ultrasonography up to 3 times in 253 white and 268 black participants, aged 13 to 36 years (mean age±standard deviation 24±3.2 years old). The development of IMT was assessed using individual growth curve modeling. A total of 521 participants with 1015 IMT measurements were eligible for this study. We found higher IMT in both left and right sides in blacks compared to whites (P,0.001) in young adulthood. Both whites and blacks showed a strong linear increase in mean IMT with age. Body ...
Association of Carotid Intima Media Thickness and Periscope Markers with Coronary Artery Disease, Risk factors and Biomarkers in Asian Indians Surrogate sub clinical mar..
Background: Increased carotid intima-media thickness is associated with higher cardiovascular disease risk. This study aimed to evaluate the contributions of cardiovascular risk factors and inheritance to segment-specific carotid intima-media thickne
To the Editor:. We congratulate Lorenz et al1 on their review of carotid intima-media thickness (IMT). The authors acknowledged that the heterogeneity among IMT measurement methodologies and study populations are the most important limitation of their metaanalysis. It is surprising however that the paper lacks discussion regarding the prognostic importance of the presence of carotid plaque. Moreover, no information was provided on plaque prevalence or on the effect that incorporation of plaque into IMT measurements likely had on the results.. Carotid plaque is a distinctive phenotype of atherosclerosis that poses a higher likelihood of rupture, thrombosis, rapid progression, responds to factors that affect endothelial function, and represents remodeling to minimize flow disturbances.2 In contrast, IMT principally represents hypertensive hypertrophy of the media and is under a substantial genetic control different from that of plaque.2 Carotid plaque most likely is not a simple continuum of IMT ...
OBJECTIVE: Carotid intima-media thickness (cIMT) is a surrogate marker of subclinical atherosclerosis and it is able to predict both coronary and cerebral vascular events. No data exist on the association between cIMT and non valvular atrial fibrillation (NVAF) type. We conduct this study with the aim to analyze the association between abnormal cIMT and NVAF type. METHODS: A cross-sectional study of the Atrial fibrillation Registry for Ankle-brachial index Prevalence Assessment-Collaborative Italian Study (ARAPACIS) has been performed. Among 2027 patients enrolled in the ARAPACIS, 673 patients, who underwent carotid ultrasound examination to assess cIMT, were included in the study. RESULTS: Among the entire population, 478 patients (71%) had cIMT , 0.90 mm. Patients with an abnormal cIMT (,0.90 mm) were significantly older and more likely hypertensive, diabetic and with a previous history of stroke than those with normal cIMT (≤0.90 mm). These patients had more permanent/persistent NVAF and ...
Based on sample participants and measurement protocols, we assessed the reliability of CIMT and plaque presence between three clinical centers. We regarded an ICC in the range 0.4-0.75 as fair to good and , 0.75 as excellent [21]. In our results, the mean CIMT values had an excellent range of ICC, while the maximum CIMT values had a fair to good range. It is probably because the mean CIMT value is less affected by an outlier than the maximum value. We attribute these results to our protocol that allows adding the plaque thickness to CIMT if plaque exists in distal CCA. This tendency was consistent with the results from other articles [14,17]. Spearman correlation showed similar tendency, too. We could not conclude the rating of each center due to the lack of absolute right CIMT value, but from these results, center 3 was likely to provide a highly reliable value. In the separate analysis done by right and left carotid arteries, only the mean CIMT value of right carotid artery had an ...
Background and aims: Previous studies have documented environmental risk factors for the progression of carotid intima-media thickness (IMT); however, few have examined genetic risk factors for the progression of carotid IMT and none has specifically examined subjects with type 2 diabetes. This study examined the association between single nucleotide polymorphisms in the adiponectin gene and the progression of carotid IMT in patients with type 2 diabetes.. Materials and methods: We performed common carotid ultrasonography at baseline and 33 39 months later in 324 consecutive subjects with type 2 diabetes. The genotypes of the adiponectin gene were determined using a single base primer extension method.. Results: The A allele of −11426A/G (P,0.05), G allele of −10066C/G (P=0.001), A allele of −8564G/A (P,0.01), A allele of −450A/G (P,0.05), and G allele of 276G/T (P,0.01) were associated with progressive carotid IMT. In the haplotype analysis, the AC/AC haplotype combination in block 1, ...
Introduction: HDL-cholesterol (HDL-c) is a strong, traditional negative cardiovascular (CV) risk factor. However, some reports suggest that extremely elevated HDL-c, i.e. hyperalphalipoproteinemia (HALP), may mark dysfunctional HDL particles, paradoxically conferring increased CV risk. Moreover, therapies aimed to increase HDL-c levels through CETP inhibition failed to demonstrate CV risk reduction despite substantial increase in HDL-c. Carotid Intima-Media Thickness (cIMT) is a reliable surrogate for atherosclerotic disease, validated for CV risk assessment. We studied cIMT among individuals with HALP.. Hypothesis: We assessed the hypothesis that HALP is independently associated with lower cIMT when compared with HDL-c levels on usual normal range.. Methods: The Brazilian Longitudinal Study for Adult Health (ELSA-Brasil) enrolled 15,105 subjects aged 35-74 years between 2008-10 for long-term follow-up, which included IMT measurements in both common carotid arteries and assessment of lipid ...
Introduction: Increased Carotid intima-media thickness (CIMT) has been shown to be predictive of future cardiovascular events in middle-age and older adults, with this outcome being detrimentally enhanced by increased body adiposity -as measured by Body Mass Index (BMI).. Hypothesis: We assessed the hypothesis that the association between BMI and CIMT varies among race (black/white) and gender groups.. Methods: B-mode ultrasound images of the far walls for both carotid arteries were obtained from 676 community-based subjects, aged 24 to 43 years, enrolled in the Bogalusa Heart Study (70% white and 43% male). CIMT, BMI and traditional cardio metabolic (CM) risk factors were measured at baseline, and a second set of CIMT imaging was performed at follow-up after an average of 6.9 years. Composite CIMT was considered for the analyses. Progression of IMT was defined as an increase of IMT between examinations, that was greater than the upper endpoint of the 95% confidence interval of the mean ...
Hypertension and arterial vasculopathy may be mutual causes and effects. It is unknown whether carotid intima-media thickness (cIMT) is reliably predictive of the presence of newly developed hypertension in the Chinese population. This study evaluated the impacts of cIMT on new-onset hypertension in a community-based population without hypertension at baseline in China. A total of 672 Chinese subjects who had complete data for demographics, baseline and follow-up blood pressure measurements, and cIMT measurements at baseline were included in our study. Baseline cIMT was obtained under standardized procedures using the GE Vivid 7 ultrasound system equipped with an 8-MHz linear array vascular probe (GE Medical Systems, Milwaukee, Wl, USA). The outcome was the incidence of hypertension at follow-up. Multivariate regression models were used to access the association between baseline cIMT and the risk of new-onset hypertension. Subjects were 51.5 ± 4.7 years old, and 32.0% were male. The mean baseline
BACKGROUND: Lower socioeconomic position (SEP) predicts higher cardiovascular risk in adults. Few studies differentiate between neighborhood and family SEP or have repeated measures through childhood, which would inform understanding of potential mechanisms and the timing of interventions. We investigated whether neighborhood and family SEP, measured biennially from ages 0 to 1 year onward, was associated with carotid intima-media thickness (IMT) at ages 11 to 12 years. METHODS AND RESULTS: Data were obtained from 1477 families participating in the Child Health CheckPoint study, nested within the Longitudinal Study of Australian Children. Disadvantaged family and neighborhood SEP was cross-sectionally associated with thicker maximum carotid IMT in separate univariable linear regression models. Associations with family SEP were not attenuated in multivariable analyses, and associations with neighborhood SEP were attenuated only in models adjusted for family SEP. The difference in maximum carotid ...
The renin-angiotensin-aldosterone system can be activated by sympathetic nervous input and is thought to have an important role in the prevalence of hypertension and cardiovascular risk in black Africans. We examined (1) the association between plasma renin responses to mental stress and a marker of sub-clinical atherosclerosis; and (2) associations between resting renin and 24-h ambulatory blood pressure. Participants were 143 urbanized black African men and women (43.1±7.7 years) drawn from a study of Sympathetic Activity and Ambulatory Blood Pressure in Africans (SABPA). After an overnight fast, participants completed the Stroop mental stress task. Blood samples were drawn during baseline and 10 min after the task to assess the concentration of active renin in plasma. Blood pressure assessments included continuous Finometer measures during the stress testing and 24-h ambulatory monitoring. Carotid intima-media thickness (CIMT) was measured using high-resolution ultrasound. Approximately 50% ...
Carotid intima-media thickness (IMT) is a measure of arterial thickening and a risk predictor for myocardial infarction and stroke. It is unclear whether IMT also predicts atrial fibrillation (AF). We explored the association between IMT and incidence of first AF hospitalization in a population-based cohort ...
A carotid intima-media thickness test (CIMT) is used to determine the extent of plaque buildup in the arteries supplying blood to the head. Learn more.
Circulating endothelial progenitor cells, endothelial function, carotid intima-media thickness and circulating markers of endothelial dysfunction in people with type 1 diabetes without macrovascular disease or ...
TY - JOUR. T1 - 25-hydroxyvitamin D is not associated with carotid intima-media thickness in older men and women. AU - Pilz, S.. AU - Henry, R.M.A.. AU - Snijder, M.B.. AU - van Dam, R.M.. AU - Nijpels, M.G.A.A.M.. AU - Stehouwer, C.D.A.. AU - Tomaschitz, A.. AU - Pieber, T.R.. AU - Dekker, J.M.. PY - 2009. Y1 - 2009. U2 - 10.1007/s00223-009-9238-6. DO - 10.1007/s00223-009-9238-6. M3 - Article. C2 - 19308629. VL - 84. SP - 423. EP - 424. JO - Calcified Tissue International. JF - Calcified Tissue International. SN - 0171-967X. IS - 5. ER - ...
Comparison of the effect on the progression of the carotid intima-media interphase thickness (GIM), arterial rigidity according to the measurement of the pulse wave speed and direct measurement of the carotid and aortic rigidities and an inflammation marker (PCR) in patients with established cardiovascular disease (myocardial infarct, atherosclerotic coronary disease), diabetes mellitus type 2 or equivalent risk of coronary disease and a low density lipoprotein level , 100 mg/dL, treated with simvastatin, pravastatin or the combination of simvastatin-ezetimibe during a period of at least one year ...
Background: The most common cause of mortality in people with diabetes is cardiovascular disease. The relation between glycosylated hemoglobin (HbA1c), a marker of glycemic control, and the development of subclinical atherosclerosis is debated. An acceptable indicator of subclinical atherosclerosis is the use of ultrasound to measure carotid intima-media thickness (CIMT). Objective: To conduct a cross-sectional study exploring the correlation between HbA1c and subclinical atherosclerosis as reflected by the carotid intima-media thickness in patients with type 2 diabetes that had no history of an atherosclerotic cardiovascular disease (ischemic heart disease or cerebrovascular accident). Methods: A total of 71, type 2 diabetic patients participated in this study. Demographic, anthropometric and laboratory measures of the participants were collected. CIMT values were measured by using a high-resolution ultrasound. Increased CIMT values were accepted as |0.9 mm. Participants were categorized into two
Methods and Results: To identify cIMT-associated genes and genetic variants, a discovery analysis using the Illumina 200K CardioMetabochip was conducted in 3430 subjects with detailed ultrasonographic determinations of cIMT from the IMPROVE (Carotid Intima Media Thickness [IMT] and IMT-Progression as Predictors of Vascular Events in a High Risk European Population) study. Segment-specific IMT measurements of common carotid, bifurcation, and internal carotid arteries, and composite IMT variables considering the whole carotid tree (IMTmean, IMTmax, and IMTmean-max), were analyzed. A replication stage investigating 42 single-nucleotide polymorphisms for association with common carotid IMT was undertaken in 5 independent European cohorts (total n=11 590). A locus on chromosome 16 (lead single-nucleotide polymorphism rs4888378, intronic in CFDP1) was associated with cIMT at significance levels passing multiple testing correction at both stages (array-wide significant discovery P=6.75×10 -7 for ...
In this study, we identified and replicated TRAF1 (lead SNP rs2416804) on chromosome 9 to be linked and associated with CIMT (pooled P=6.02×10-7). We additionally identified 2 genomic regions on chromosomes 4 and 17 with suggestive linkage to CIMT, which have not been reported before. Finally, we could replicate previously reported linkage findings on chromosomes 13 and 14.. Our combined linkage and association analysis identified a SNP in TRAF1 on chromosome 9, as well as a cluster of SNPs on chromosome 6. TRAF proteins mediate the signal transduction from receptors of the tumor necrosis factor receptor and were detected in plaques from atherosclerotic lesions.31 A genome-wide association study and a candidate gene study identified TRAF1 as susceptibility genes for rheumatoid arthritis (RA).32,33 RA is associated with increased mortality, largely as a consequence of coronary artery disease. It was, thus, hypothesized that inflammation associated with RA contributes to accelerated ...
Moon et al conducted a 5-year cohort study to know the association between carotid atherosclerosis and progression of cognitive impairment in 348 older adults.1 Cognitive function was assessed using standard test batteries, and carotid atherosclerosis was determined by ultrasonographic measurement of intima-media thickness (IMT) and plaque formation in the carotid artery. The authors adopted multivariate logistic regression analyses for predicting the progress of cognitive impairment or mild cognitive impairment by adjusting age, education, mood, and general health status. Odds ratio (95% confidence interval) of baseline mean carotid IMT for subsequent progression of cognitive impairment and mild cognitive impairment in subjects with normal baseline cognition were 1.251 (1.006-1.555) and 1.325 (1.045-1.679), respectively. In contrast, carotid plaque did not significantly contribute to cognitive impairment after full adjustment. I have some queries on their study.. First, the authors handled ...
Our study showed that in our sample, patients with type 1 diabetes had a higher IMT compared with the control subjects. Despite having type 1 diabetes for a relatively long time, our patients with type 1 diabetes had a lower IMT than expected, similar to the findings of another study [13]. In our study, in patients with type 1 diabetes, having a family history of type 2 diabetes was associated with a 4.4% increase in carotid IMT and unlike the control group, women with type 1 diabetes had a IMT as high as men.. In the control group, the female gender was associated with a thinner IMT, but this association was not found in our patients with type 1 diabetes. A study that evaluated the distribution of IMT according to age in the general population showed that men had a higher IMT compared with women [39]. These findings could reflect a loss of gender protection for CVD risk in women with type 1 diabetes as suggested by The Diabetes UK Cohort Study and another study [40, 41]. In fact, in patients ...
Background: Type 2 diabetes is a common disease with increased mortality and morbidity due to cardiovascular disease (CVD). This thesis is based on three studies that evaluated traditionally used and emerging risk markers to identify individuals with high-risk of developing CVD in middle-aged men and women with type 2 diabetes. One study was conducted to compare the equivalence between two different ultrasound techniques to measure intima-media thickness since IMT was used to evaluate subclinical atherosclerosis as a surrogate endpoint.. Methods: Data from the cohort study, cardiovascular risk in type 2 diabetes - a prospective study in primary care (CARDIPP) was used in paper I, III and IV. In paper I, baseline data from the first 247 subjects was analysed. Associations between traditionally measured lipids, apolipoproteins, glycaemic control and low-grade inflammation and IMT were analysed.. In paper III, the full baseline cohort, with data from 761 subjects from the CARDIPP study was ...
Our findings suggest endothelial injury in obese children. Intima-media thickness and vWF level might be useful to identify the degree of endothelial damage.
We have used carotid IMT rather than CHD as our outcome. Carotid IMT has been shown to be strongly associated with prevalent and incident CHD.13,18 It has been suggested that the difference in IMT between women and men may be explained by differences in luminal diameter.22 However, this has been shown not to be the case in the large Tromso study.14 There was a differential in the response between women and men in our study and a difference in the nature of the sampling frame for women and men. Men were survivors of a prospective cohort, whereas women were a newly selected random sample. While among the men responders did not appear to differ from non-responders with respect to age, women who responded were younger than those who did not and women were on average slightly younger than men in the final study sample. All results presented in this study are adjusted for age. Mean blood pressure, lipid levels, and waist-hip ratios for both women and men from this study are similar to those for ...
Results A total of 76 patients were screened and 22 RA patients who were in low disease activity or remission were included. Patients with RA had significantly higher median cIMT, 0.53 (IQR0.13) mm compared to controls, 0.47 (IQR 0.14) mm, p=0.01. In RA patients, the cIMT had significant positive correlation with age (rs=0.84, p=0.00), systolic BP (rs=0.45, p=0.04), waist circumference (rs=0.43, p=0.04), total cholesterol (rs=0.54, p=0.01), BMI (rs=0.45, p=0.04) and serum IL-17 (rs=0.45, p=0.03) but negative correlation with total HDL (rs=-0.43, p=0.05). ...
Methods. The study population included 58 patients undergoing percutaneous coronary intervention (PCI) with stenting and at least 10 months of follow-up. All patients underwent ultrasound detection of brachial artery reactivity 30 days after PCI. Flow mediated dilatation (FMD) was investigated after 5 minutes of occlusion of the artery and nitroglycerin mediated dilation (NMD) was investigated after administration of sublingual nitrates. Vascular echography was performed to measure intima media thickness (IMT) of carotid arteries. At baseline we evaluated all the established traditional cardiovascular risk factors. We also subdivided our study cohort according to values of FMD in patients with FMD above and patients below the median value ...
Bronner Handwerger, ND. Assessing cardiovascular risk factors is always part of the naturopathic intake. The question arises as to how we assess these risks. We recognize that traditional markers like cholesterol, HDL, LDL, Lp(a), fibrinogen, homocysteine and even cardio CRP provide us with valuable information, along with family history. Although these are important to assess, they still do not give us the kind of reliable information we are looking for.. Cardiovascular disease is the No. 1 killer in the U.S. for both men and women. Heart disease and stroke account for almost six million hospitalizations each year, and more than 40% of all people age 45 and older have some form of cardiovascular disease. Approximately 1.1 million Americans are expected to have a new or recurrent heart attack this year, and 60% of all deaths in the U.S. are attributed to cardiovascular disease. A more sobering statistic is that 40%-50% of all heart attack patients have a normal cholesterol or lipid profile, ...
Results The groups were similar in age and gender. The biomass fuel group had greater unadjusted mean CIMT (0.66 vs 0.60 mm; p,0.001), carotid plaque prevalence (26% vs 14%; p=0.03), systolic blood pressure (118 vs 111 mm Hg; p,0.001) and median household PM2.5 (280 vs 14 µg/m3; p,0.001). In multivariable regression, the biomass fuel group had greater mean CIMT (mean difference=0.03 mm, 95% CI 0.01 to 0.06; p=0.02), a higher prevalence of carotid plaques (OR=2.6, 95% CI 1.1 to 6.0; p=0.03) and higher systolic blood pressure (mean difference=9.2 mm Hg, 95% CI 5.4 to 13.0; p,0.001).. ...
Methods: 48-wk prospective cohort study to compare changes in IMT and inflammation markers in ART-naïve HIV+ adults and age, sex and race-matched healthy controls. Diabetes and cardiovascular disease (CVD) were exclusionary. ANCOVA was used to adjust means. Correlation coefficients and multivariable linear regression were used to explore relationships between baseline and change in IMT and inflammation markers ...
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TY - JOUR. T1 - Machine learning to predict rapid progression of carotid atherosclerosis in patients with impaired glucose tolerance. AU - Hu, Xia. AU - Reaven, Peter D.. AU - Saremi, Aramesh. AU - Liu, Ninghao. AU - Abbasi, Mohammad Ali. AU - Liu, Huan. AU - Migrino, Raymond Q.. AU - the ACT NOW Study Investigators, ACT NOW Study Investigators. PY - 2016/12/1. Y1 - 2016/12/1. N2 - Objectives: Prediabetes is a major epidemic and is associated with adverse cardio-cerebrovascular outcomes. Early identification of patients who will develop rapid progression of atherosclerosis could be beneficial for improved risk stratification. In this paper, we investigate important factors impacting the prediction, using several machine learning methods, of rapid progression of carotid intima-media thickness in impaired glucose tolerance (IGT) participants. Methods: In the Actos Now for Prevention of Diabetes (ACT NOW) study, 382 participants with IGT underwent carotid intima-media thickness (CIMT) ultrasound ...
1 Maier H. Präparierkurs Präparieranweisungen und Theorie. 2., erw. Aufl. Köln: Deutscher Ärzte-Verlag; 1987. 2 Faxon DP, Creager MA, Smith SC Jr, Pasternak RC, Olin JW, Bettmann MA, et al. Atherosclerotic Vascular Disease Conference: executive summary: Atherosclerotic Vascular Disease Conference proceeding for healthcare professionals from a special writing group of the American Heart Association. Circulation. 2004;109(21):2595-604. 3 Ross R, Faggiotto A, Bowen-Pope D, Raines E. The role of endothelial injury and platelet and macrophage interactions in atherosclerosis. Circulation. 1984;70(5 Pt 2):III77-82. 4 Gossl M, Lerman LO, Lerman A. Frontiers in nephrology: early atherosclerosis - a view beyond the lumen. J Am Soc Nephrol. 2007;18(11):2836-242. 5 Weber C, Noels H. Atherosclerosis: current pathogenesis and therapeutic options. Nat Med. 2011;17(11):1410-22. 6 Hansson GK. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med. 2005;352(16):1685-95. 7 Hegele RA. The ...
TY - JOUR. T1 - Measurements of Intima-Media Thickness in Chinese Patients with Carotid or Aortic Plaque can Not Exclude Significant Coronary Stenosis. AU - Lin, Mei Shu. AU - Hong, Chi Tzong. AU - Chang, Nen-Chung. PY - 2008/6. Y1 - 2008/6. KW - Chinese. KW - Coronary artery disease. KW - Aorta. KW - Carotid artery. KW - Atherosclerotic plaque. KW - Intima-media thickness UR - http://readopac1.ncl.edu.tw/nclJournal/search/detail.jsp?sysId=0006563928&dtdId=000040&search_type=detail&la=ch%20?iframe=true. M3 - Article. VL - 2. SP - 32. EP - 45. JO - 臺灣心臟超音波學會雜誌. JF - 臺灣心臟超音波學會雜誌. IS - 2. ER - ...
OBJECTIVE: Increased arterial stiffness and carotid intima-media thickness (IMT) are considered independent predictors of cardiovascular events. The aim of this study was to compare a system recently developed in our laboratory for automatic assessment of these parameters from ultrasound image sequences to a reference radio frequency (RF) echo-tracking system. METHODS: Common carotid artery scans of 21 patients with cardiovascular risk factors and 12 healthy volunteers were analyzed by both devices for the assessment of diameter (D), IMT, and distension (DeltaD). In the healthy volunteers, analyses were repeated twice to evaluate intraobserver variability. Agreement was evaluated by Bland-Altman analysis, whereas reproducibility was expressed as a coefficient of variation (CV). RESULTS: Regarding the agreement between the two systems, bias values +/- SD were 0.060 +/- 0.110 mm for D, -0.006 +/- 0.039 mm for IMT, and -0.016 +/- 0.039 mm for DeltaD. Intraobserver CVs were 2% +/- 2% for D, 5% +/- ...
At baseline, 783 patients were recruited for the evaluation. During the follow-up period (5.46 ± 0.39 years), 50 coronary events and 35 strokes were recorded. These patients were older and had higher systolic and diastolic BP, higher baPWV, higher IMT, and higher FRS, compared with those without such events. CVD occurred more frequently in men than in women.. The Kaplan-Meier curves showed lower event-free rates with higher IMT (using the fourth quintile of IMT as the cutoff value; log-rank χ2 = 8.87; P = 0.03), baPWV (using the fourth quintile of baPWV as the cutoff value; log-rank χ2 = 9.83; P = 0.02), and Framingham score (FRS ≤10%, FRS ,10% but ≤20%, FRS ,20%; log-rank χ2 = 23.1; P , 0.001).. Next, we examined the ability to predict CVD at ∼5 years by evaluating ROC. The areas under the ROC curves for IMT and baPWV were similar (0.590 and 0.583, respectively), although that for FRS was modestly higher (0.645). Simple addition of both IMT and baPWV to FRS results in only a modest ...
Results: The level of glycosylated hemoglobin and CIMT progressively increased across quintiles of IGP (P for trend = 0.01 for both). In univariate analysis, all examined glycemic parameters were significantly correlated with CIMT. IGP (r = 0.40; P = 0.006) showed the strongest correlation with CIMT, which remained significant in multiple linear regression analysis (R-2 = 0.26; P = 0.01). IGP was associated with a significant increase of CIMT in tertiles of glycosylated hemoglobin. IGP occurred within 1 h from the start of the meal in 95% of the entire diabetic population ...
Results For CIMT≥1.38 mm (≥3rd quartile), the sensitivity and specificity of ≥3-territory involvement were 90.0% and 82.6%. MA≥6.85 mg/dl (≥3rd quartile), the sensitivity and specificity of ≥2-territory involvement were 54.9% and 83.3%. CV events occurred in 104 subjects. The Kaplan-Meier 2-year CV event-free survival was 93.9% and 95.7%; 95.7% and 89.6%; 73.9% and 72.3%; 59.6% and 66% in patients with mean-CIMT and MA values in the 1st; 2nd; 3rd and 4th quartile. The multivariable Cox proportional hazard model identified: mean-CIMT ≥1.38 mm (RR=1.83; CI 1.049 to 3.196; p,0.001), MA≥6.84 mg/dl (RR=0.99; CI 0.576 to 1.703; p,0.001). Inclusion of CIMT into the stratification model significantly improved the prediction of CV event risk (Δχ2=7.098, p,0.001) whereas the impact of the MA is not significant (△χ2=0.002, p,0.001).. ...
Numerous studies over the past 2 decades have demonstrated the benefit of low-density lipoprotein (LDL) cholesterol lowering on heart attack, stroke, and cardiac death (1). Both invasive and noninvasive imaging approaches have been used as surrogate markers to demonstrate benefits of LDL lowering on atherosclerosis. Studies using intravascular ultrasonography (IVUS) of the coronary arteries have demonstrated that statin initiation is associated with halting of plaque progression, and, in fact, with more potent statins, evidence of plaque regression (2). Carotid intima-media thickness studies with ultrasonography have likewise demonstrated benefit of statin therapy (3). These studies have primarily been conducted over the first year or 2 after initiation of statins, and the endpoint used has been coronary plaque volume or greatest plaque area in the case of IVUS and carotid wall thickness in the case of carotid intima-media thickness. Noninvasive imaging with magnetic resonance imaging (MRI) of ...
TY - JOUR. T1 - Association of pathobiologic determinants of atherosclerosis in youth risk score and carotid artery intima-media thickness in asymptomatic young heterozygous familial hypercholesterolemia patients. AU - Cheng, Hao Ming. AU - Ye, Zhong Xuan. AU - Charng, Min Ji. PY - 2011/9. Y1 - 2011/9. N2 - Background: Familial hypercholesterolemia (FH) is an inherited disorder characterized by extremely high cholesterol level, accelerated atherosclerosis and premature cardiovascular disease.We need an early risk stratification method for this population. Arisk score formula to estimate the probability of advanced atherosclerosis using coronary heart disease risk factors was developed for persons 15-34 years of age by the Pathobiological Determinants of Atherosclerosis in Youth (PDAY) study. This studys aim was to investigate the relation between PDAY risk score and carotid intima-media thickness (IMT) and inflammation markers in asymptomatic young FH subjects. Methods: We included 23 ...
TY - JOUR. T1 - Carotid intima-media thickness is a useful screening tool to detect coronary artery plaque in type 2 diabetic patients with zero calcium score. AU - Inohara, Taku. AU - Niinuma, Hiroyuki. AU - Nishihara, Shuzo. AU - Makita, Zenji. AU - Sanoyama, Kyou. AU - Niwa, Koichiro. N1 - Copyright: Copyright 2018 Elsevier B.V., All rights reserved.. PY - 2014/3/1. Y1 - 2014/3/1. KW - Calcium score. KW - Carotid intima medial thickness. KW - Computed tomography. KW - Coronary artery disease. KW - Diabetes mellitus. UR - http://www.scopus.com/inward/record.url?scp=84894040178&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=84894040178&partnerID=8YFLogxK. U2 - 10.1016/j.ijcard.2013.12.110. DO - 10.1016/j.ijcard.2013.12.110. M3 - Article. C2 - 24438939. AN - SCOPUS:84894040178. VL - 172. SP - e132-e134. JO - International Journal of Cardiology. JF - International Journal of Cardiology. SN - 0167-5273. IS - 1. ER - ...
Background Hypertension, identifiable by elevated blood pressure (BP), is a heterogeneous multifactorial disorder. Epicardial adipose tissue (EAT), a special fat depot that is related to visceral fat rather than total adiposity, shares the same microcirculation with myocardial tissue and coronary vessels. Recent studies have identified EAT as an active organ, which secretes several mediators, called adipokines, affecting the vascular system. The aim of this study was to evaluate the potential association between EAT and BP, endothelial function, carotid intima-media thickness (CIMT), and pulse wave velocity (PWV) independent of conventional and novel metabolic risk factors in patients with previously untreated hypertension. ...
We have reported that psoriatic arthritis (PsA) patients without overt cardiovascular diseases have evidence of premature atherosclerosis as indicated by an increased carotid intima-media thickness (IMT).1 Whether an increase in IMT reflects current (but reversible) inflammation of the vessel wall rather than more permanent structural vessel changes in PsA has never been assessed. We undertook a prospective, observational study to determine whether a 12-week treatment of tumour necrosis factor alpha (TNFα) blockers may reduce IMT in patients with active PsA, and whether the changes in IMT can be sustained in patients who were continued on long-term TNFα blockers.. Twenty consecutive PsA patients with active disease were recruited to receive TNFα blockers. After 12 weeks, nine patients continued (group 1) while 11 patients discontinued TNFα blockers due to financial constraints (group 2). Twenty PsA patients who were naive to TNFα blockers were recruited as controls (group 3). Patients … ...
Fingerprint Dive into the research topics of Increased carotid artery intima-media thickness and impaired endothelial function in psoriasis. Together they form a unique fingerprint. ...
In the present analysis, we observed no additional value of measurement of mean common CIMT in risk classification among 17 254 individuals free from symptomatic CVD, but with elevated blood pressure levels. For those at intermediate risk, the addition of common CIMT to an existing cardiovascular risk score is small but statistically significant. However, the decision on whether or not to implement common CIMT measurements in individuals with elevated blood pressure levels at intermediate risk depends on the balance between costs of additional risk assessment by CIMT measurements and effectiveness in preventing CVD.. In asymptomatic individuals with elevated blood pressure, guidelines recommend cardiovascular risk assessment and suggest screening for subclinical vascular damage.1,5-7 It has been suggested that providing a more accurate assessment of vascular damage related to hypertension may lead to a more precise stratification of CVD risk.20 As such, the 2007 ESH/ESC hypertension guidelines ...
This study shows that spironolactone prevents the progression of carotid CIMT in HD patients. The protective effect of spironolactone was observed in the absence of RAS inhibitors. Atherosclerosis is accepted as a common mechanism underlying all CVDs and atherosclerotic CVD is a significant cause of morbidity and mortality in patients with ESRD (1-3). Prospective studies have shown an association between increased CIMT and the incidence of CVDs (16-18). In fact, CIMT is a well described surrogated marker for cardiovascular risk (10-14). A thickened CIMT correlates with the presence of myocardial infarction and stroke by cross-sectional analysis (13). In some countries, recommendations already suggest that carefully performed IMT measurement can add incremental information to traditional risk factor assessment (European Society of Cardiology Guidelines). The main advantage of using CIMT as an end point in a trial concerning morbidity and mortality is the considerable reduction in sample size and ...
Background:B-mode ultrasound measurements of the echolucency of the carotid intima-media may hold information on cardiovascular risk. The information obtained from this measurement may depend on which gain settings are used. We studied the effect of gain settings on echolucency measurements and its consequences on risk factor relations and treatment effects.Methods:We used two approaches. In the first, we examined the relationship between calibration, gain and common grey-scale median (GSM) from repeated ultrasound images obtained from four healthy individuals at gain settings ranging from -20 to 20dB. In the second, we evaluated the effect of gain settings on the relation of risk factors and statin treatment with common GSM, using images from 325 participants of the Measuring Effects on Intima-Media Thickness: an Evaluation of Rosuvastatin (METEOR) study with documented gain settings. Echolucency of the carotid intima-media was measured from ultrasound images using PaintShop Pro and Artery ...
TY - JOUR. T1 - Individual measurement and significance of carotid intima, media, and intima-media thickness by B-mode ultrasonographic image processing. AU - Bae, Jang Ho. AU - Kim, Wuon Shik. AU - Rihal, Charanjit S.. AU - Lerman, Amir. PY - 2006/10/1. Y1 - 2006/10/1. N2 - OBJECTIVE - We assessed the clinical significance of intima (IT), media (MT), and intima-media (IMT) thickness of the common carotid artery using B-mode ultrasonographic image processing. METHODS AND RESULTS - One hundred seventy consecutive patients underwent common carotid artery scanning using high-resolution ultrasonography. A total of 150 patients could be analyzed off-line using ultrasonographic image processing, devised for individual measurement of IT, MT, and IMT. By univariate analysis, IT (range, 0.27 to 0.41 mm) was associated with age, whereas MT (range, 0.27 to 0.74 mm) and IMT (range, 0.49 to 1.12 mm) were associated with age, fibrinogen, and creatinine. Among atherosclerosis risk factors, hypertension was ...
TY - JOUR. T1 - Characterization of intravascular cellular activation in relationship to subclinical atherosclerosis in postmenopausal women. AU - Jayachandran, Muthuvel. AU - Garovic, Vesna D.. AU - Mielke, Michelle M.. AU - Bailey, Kent R.. AU - Lahr, Brian D.. AU - Miller, Virginia M.. PY - 2017/9. Y1 - 2017/9. N2 - Objective Mechanisms and interactions among intravascular cells contributing to development of subclinical atherosclerosis are poorly understood. In women, both menopausal status and pregnancy history influence progression of atherosclerosis. This study examined activation and interactions among blood elements with subclinical atherosclerosis in menopausal women with known pregnancy histories. Methods Carotid intima-media thickness (CIMT), as a marker of subclinical atherosclerosis, was measured using B-mode ultrasound in age- and parity-matched women [40 with and 40 without a history of preeclampsia] 35 years after the index pregnancy. Interactions among intravascular cells (38 ...
We have shown that even after adjusting for multiple confounding factors, a tertiary care cohort of psoriasis patients have a 2.67-fold higher odds of having atherosclerosis compared to controls. The most striking finding was that after age stratification, almost half (49 %) of patients with psoriasis aged 30-39 years had evidence of subclinical atherosclerosis as compared to 15 % of controls. These findings are suggestive that psoriasis may contribute to the inflammatory cascade of atherosclerosis and that the younger a patient develops psoriasis, the higher the CVD risk. These findings are consistent with recent observations from preclinical models systems, wherein chronic skin-contained inflammation, but not acute, promoted the acceleration of arterial thrombosis [19] and [20]. In addition, other investigators have also reported observational studies demonstrating relatively higher measures of association with CV events in younger individuals [25, 42-44]. Psoriasis sufferers with ...
SwePub titelinformation: Carotid Intima-Media Thickness Progression and Risk of Vascular Events in People With Diabetes: Results From the PROG-IMT Collaboration
After controlling for age and sex, we report not only that CHD risk factors but also that CCA and ICA IMTs are elevated in individuals before the onset of clinical diabetes. Moreover, increased CCA IMT predicted diabetes. Hence, in our study population, we have established that early atherogenesis, not merely elevated cardiovascular risk factors, is present before the development of clinical diabetes, and thus, enhanced atherogenesis is not solely dependent on the clinical manifestation of diabetes.. Jarrett,15 Jarrett and Shiply,16 and later Stern17,18 hypothesized not only that diabetes and cardiovascular disease are related as cause and effect but also that both conditions originate from a common soil. This hypothesis suggests an atherogenic state before the onset of clinical diabetes, which is consistent with the regularly reported finding that CHD risk factors are elevated in prediabetic individuals1-5 and the recently reported finding in the Nurses Health Study (NHS) of elevated ...
Objectives: This study aims to evaluate the relationship between serum homocysteine levels and atherosclerotic plaques in carotid arteries in female patients with rheumatoid arthritis (RA). ...
This proposed prospective, randomized, controlled study aims to investigate the effects of high flux dialyser use and ultra pure dialysate utilization on cardiovascular disease by evaluating cardiovascular morbidity and mortality, progression of carotid artery intima-media thickness and coronary artery calcifications, inflammatory state, lipid levels, nutritional status, and erythropoietin requirement in hemodialysis patient population. It is hypothesized that both interventions in this project may diminish cardiovascular disease in hemodialysis patients.. Their beneficial effects may be directly represented by significantly reduced cardiovascular morbidity and mortality. The proposed additional investigations, such as a possible decrease in the progression of coronary artery calcification and carotid artery intima-media thickness, will help us to understand the mechanisms of the expected reduction or serve as surrogate markers of atherosclerosis, in case the benefit of the interventions cannot ...
Evidences indicate that skeleton works not only as a structural scaffold but also as an endocrine organ. Many bioactive factors secreted from bone, such as osteocalcin and osteoprotegerin, have a regulatory role in energy metabolism [21, 22]. Recent studies have suggested a potentially important role for osteocalcin in regulating the function of vascular endothelial cells, and the cardiovascular system [23, 24]. This suggests osteocalcin could be involved in the development of CAD. Several studies have investigated the association between osteocalcin and atherosclerosis, but results have not been consistent. Some studies suggest osteocalcin may actually be protective against early atherosclerosis. For example, a study from Korea demonstrated an independent effect of osteocalcin on vascular endothelial cells, suggesting that osteocalcin could have beneficial effects on atherosclerosis [25]. Our previous study in high fat diet animals indicate that osteocalcin has an endothelial-protective effect ...
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Vascular aging, as assessed by structural and functional arterial properties, is an independent predictor of cardiovascular risk. We hypothesized that the number of cardiovascular risk factors determines the progression of vascular aging. One hundred forty-two subjects (mean age 51.9 years, 94 men) without established cardiovascular disease were investigated in 2 examinations over a 2-year period. Subjects were classified at baseline according to their number of risk factors (from 0 to 2 and more). Subjects had determinations of carotid-femoral pulse wave velocity, aortic augmentation index, brachial flow-mediated dilatation, and common carotid intima-media thickness and their annual absolute changes were calculated. Subjects with more risk factors had a gradual higher annual progression of pulse wave velocity (0.092 m/s/y for 0, 0.152 m/s/y for 1, and 0.352 m/s/y for 2 and more; P=0.007). Patients with both hypertension and dyslipidemia have 4× higher annual progression rate compared with ...
Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of mortality and disability in most countries (1). Approximately 30% of first acute events are fatal, and survivors often experience sequelae and a shortened life expectancy (2,3). Primary prevention is thus the best approach to fighting this pandemic disease. Current algorithms for risk detection, which combine behavioral, clinical, and biochemical markers, are of limited accuracy, and better risk stratification methods are definitely needed (4,5).. Used in combination with traditional risk factors, data on subclinical atherosclerosis can provide additional information about the risk of myocardial infarction, stroke, and cardiovascular disease (CVD) mortality (6-8). Carotid wall intima-media thickness estimated from ultrasonographic images has been proposed as a surrogate measure of subclinical atherosclerosis (9). Whereas some prospective studies have shown that intima-media thickness adds predictive capacity to traditional ...
Afaq F, Saleen M, et al. Anthocyanin- and Hydrolyzable Tannin-Rich Pomegranate Fruit Extract Modulates MAPK and NF-kappaB Pathways and Inhibits Skin Tumorigenesis in CD-1 Mice. Int. J. Cancer 2005; 113(3): 423-433.. Aviram M, Rosenblat M, Gaitini D, et al. Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intima-media thickness, blood pressure and LDL oxidation. Clin Nutr 2004; 23(3): 423-33.. Rasheed Z, Akhtar N, et al. Polyphenol-rich pomegranate fruit extract (POMx) suppresses PMACI-induced expression of pro-inflammatory cytokines by inhibiting the activation of MAP Kinases and NF-κB in human KU812 cells. Journal of Inflammation 2009; 6(1). ...
Afaq F, Saleen M, et al. Anthocyanin- and Hydrolyzable Tannin-Rich Pomegranate Fruit Extract Modulates MAPK and NF-kappaB Pathways and Inhibits Skin Tumorigenesis in CD-1 Mice. Int. J. Cancer 2005; 113(3): 423-433.. Aviram M, Rosenblat M, Gaitini D, et al. Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intima-media thickness, blood pressure and LDL oxidation. Clin Nutr 2004; 23(3): 423-33.. Rasheed Z, Akhtar N, et al. Polyphenol-rich pomegranate fruit extract (POMx) suppresses PMACI-induced expression of pro-inflammatory cytokines by inhibiting the activation of MAP Kinases and NF-κB in human KU812 cells. Journal of Inflammation 2009; 6(1). ...
Ultrasound study to assess Carotid Intima Media Thickness in an office setting 525 patients to be enrolled at seven medical centers DALLAS - November 13, 2005 - SonoSite, Inc. (NASDAQ: SONO), the world leader in hand-carried ultrasound, announced today at the 2005 American Heart Association (AHA) Scientific Sessions that it is initiating a multi-center study to determine whether the addition of an ultrasound examination evaluating carotid artery wall thickness (CIMT), performed in the office setting, will provide a more effective tool for risk assessment and prevention of cardiovascular disease than current clinical methods alone. Over 20 years of clinical research has shown that the thickness (T) of the two innermost layers of the carotid artery wall, the intima (I) and media (M), begins to increase before plaque is evident within the vessel. This increased wall thickness is associated with an increased risk of cardiovascular disease, the leading cause of mortality and disability in the United States
We read with interest the article by Mita et al. (1) in Diabetes Care reporting a beneficial effect of sitagliptin on the progression of carotid intima-media thickening in Japanese patients with type 2 diabetes. This article parallels another article highlighting the prevention of the progression of carotid atherosclerosis by alogliptin in patients with type 2 diabetes (2). The two articles appeared in the same journal (Diabetes Care) in 2016, were conducted by the same group, had the same first author, and had the same (almost identical) baseline values of carotid intima-media thickness (IMT) among the patients with diabetes. The two studies also had important differences concerning duration of diabetes (17.2 years sitagliptin vs. 9 years alogliptin), baseline HbA1c (8.1% vs. 7.3%), and insulin use (all sitagliptin patients vs. no alogliptin patients). So, at least in Japanese people, three of the main clinical aspects that characterize type 2 diabetes-duration of disease, baseline HbA1c, and ...
Background- Genome-wide association studies have recently identified a locus on chromosome 9p21 that influences risk of coronary artery disease (CAD). The effect of the locus on early markers of atherosclerosis is unknown. We examined its association with carotid intima-media thickness (CIMT) and brachial flow-mediated dilatation (FMD). Methods and Results- We genotyped 2277 individuals, age 24 to 39 years, from the Cardiovascular Risk in Young Finns Study with CIMT and FMD measurements and 1295 individuals, age 46 to 76 years, from the Health 2000 Survey with CIMT for rs1333049, the chromosome 9p21 variant showing the strongest association with CAD. Both mean and maximum CIMT were significantly higher (P,0.001) in the older subjects of the Health 2000 Survey compared with the Young Finns Study. However, there was no association of the rs1333049 genotype with either mean or maximum CIMT at either age (P=0.959 and 0.977 for the 2 phenotypes in the Young Finns Study and P=0.714 and 0.725 in the ...
Childhood obesity is associated with an increased carotid intima-media thickness (IMT) and stiffness. Increased carotid wall thickening and rigidity are considered markers of subclinical atheroscleros
Aims: Vitamin E (Vit-E) may preferentially improve cardiovascular risk in haptoglobin 2-2 (Hp2-2) genotype diabetes individuals. We studied the impact of Vit-E supplementation on vascular function in diabetes individuals stratified by haptoglobin genotype in Singapore.. Methods: In this 24-week, double blind, placebo-controlled RCT, we recruited 187 subjects (101 Hp2-2, 86 non-Hp2-2).. Intervention: alpha-tocopherol-400 IU.. Primary outcome: Change in EndoPAT-derived reactive-hyperaemia index (RHI) and augmentation index (AIx); Secondary Outcomes: Pulse-Wave velocity (Sphygmocor-PWV), carotid intima media thickness (CIMT), inflammation (hsCRP), derivatives of reactive-oxygen metabolites (dROMs), biological antioxidant-potential (BAPs), HbA1c, LDL-C, HDL-C and oxidised LDL-C (ox-LDL).. Results: Overall, with Vit-E supplementation no significant change in RHI, PWV, CIMT, hsCRP, dROMS, BAPs, HDL-C and HbA1c was observed (p , 0.05); an increase in LDL-C with concomitant decrease in ox-LDL, and ...
A Syngle1, I Verma2, N Garg2, P Krishan2. 1Cardio Rheuma, Healing Touch City Clinic and Fortis Hospital, Chandigarh, India,. 2Department of Pharmaceutical Sciences & Drug Research, Punjabi University, Patiala, India. Objectives: Ankylosing spondylitis (AS) is an inflammatory disease associated with premature atherosclerosis. We hypothesized that depleted endothelial progenitor cells (EPCs), mediators of inflammation and carotid intima media thickness (cIMT) are associated with atherosclerosis in other populations and would be increased and associated with the severity of coronary atherosclerosis in patients with AS. Methods: We compared 30 patients of AS with 22 healthy controls. CD34+, CD133+, were used to quantify EPCs using flow cytometry. Flow-mediated dilatation (FMD) was assessed by using AngioDefenderTM (Everist Health, Ann Arbor, MI, United States). CIMT was measured using ultrasonography. Pro-inflammatory cytokines and inflammatory disease activity measures, Bath Ankylosing Spondylitis ...
A Syngle1, I Verma2, N Garg2, P Krishan2. 1Cardio Rheuma, Healing Touch City Clinic and Fortis Hospital, Chandigarh, India,. 2Department of Pharmaceutical Sciences & Drug Research, Punjabi University, Patiala, India. Objectives: Ankylosing spondylitis (AS) is an inflammatory disease associated with premature atherosclerosis. We hypothesized that depleted endothelial progenitor cells (EPCs), mediators of inflammation and carotid intima media thickness (cIMT) are associated with atherosclerosis in other populations and would be increased and associated with the severity of coronary atherosclerosis in patients with AS. Methods: We compared 30 patients of AS with 22 healthy controls. CD34+, CD133+, were used to quantify EPCs using flow cytometry. Flow-mediated dilatation (FMD) was assessed by using AngioDefenderTM (Everist Health, Ann Arbor, MI, United States). CIMT was measured using ultrasonography. Pro-inflammatory cytokines and inflammatory disease activity measures, Bath Ankylosing Spondylitis ...
A Syngle1, I Verma2, N Garg2, P Krishan2. 1Cardio Rheuma, Healing Touch City Clinic and Fortis Hospital, Chandigarh, India,. 2Department of Pharmaceutical Sciences & Drug Research, Punjabi University, Patiala, India. Objectives: Ankylosing spondylitis (AS) is an inflammatory disease associated with premature atherosclerosis. We hypothesized that depleted endothelial progenitor cells (EPCs), mediators of inflammation and carotid intima media thickness (cIMT) are associated with atherosclerosis in other populations and would be increased and associated with the severity of coronary atherosclerosis in patients with AS. Methods: We compared 30 patients of AS with 22 healthy controls. CD34+, CD133+, were used to quantify EPCs using flow cytometry. Flow-mediated dilatation (FMD) was assessed by using AngioDefenderTM (Everist Health, Ann Arbor, MI, United States). CIMT was measured using ultrasonography. Pro-inflammatory cytokines and inflammatory disease activity measures, Bath Ankylosing Spondylitis ...
Chronic inflammatory diseases, such as rheumatoid arthritis, systemic lupus erythematosus, and psoriasis and infections, such as periodontal disease and HIV, are associated with an increased risk of cardiovascular disease. Patients with these disorders also have an increase in coronary artery calcium measured by CT and carotid intima media thickness measured by ultrasound. Inflammation and infections induce a variety of alterations in lipid metabolism that may initially dampen inflammation or fight infection, but if chronic could contribute to the increased risk of atherosclerosis. The most common changes are decreases in serum HDL and increases in triglycerides. The increase in serum triglycerides is due to both an increase in hepatic VLDL production and secretion and a decrease in the clearance of triglyceride rich lipoproteins. The mechanisms by which inflammation and infection decrease HDL levels are uncertain. There is also a consistent increase in lipoprotein (a) levels due to increased
Background Atherosclerosis is the leading cause of death in patients with diabetes. We aimed to evaluate the association between ankle-brachial index (ABI) and toe-brachial index (TBI) with carotid intima-media thickness (CIMT) in patients with type 2 diabetes (T2DM). Methods This cross sectional study included 296 patients with T2DM who met the American Diabetes Association criteria for the assessment of peripheral arterial atherosclerosis. The ABI [less than or equal to] 0.9 and TBI [less than or equal to] 0.7 were considered as abnormal values. Linear and logistic regression analyses were performed to evaluate the association between TBI/ABI and CIMT. Results Right CIMT was significantly greater in the low TBI group (p = 0.03) while, left CIMT did not show a significant difference. Each 0.1-unit decrease in TBI value was independently associated with 0.017 mm increase in the right CIMT ([beta] ± SE; -0.017 ± 0.005, p = 0.002) and with odds of the presence of increased CIMT [odds ratio and ...
The primary prevention of cardiovascular disease involves classifying individuals according to their global cardiovascular risk. However, those at intermediate risk represent a particular challenge; while some may require aggressive treatment, others may be best managed by lifestyle measures alone. Biomarkers that have shown promise in improving risk discrimination include carotid intima-media thickness (CIMT), coronary artery calcium (CAC) scoring, brachial flow-mediated dilation (FMD), ankle-brachial index (ABI), high-sensitivity C-reactive protein (CRP) and, in addition, having a family history of coronary heart disease (CHD). Determining whether - and by how much - risk prediction can be improved by various markers could help to determine the most efficient strategy for the use of primary prevention drugs.. 1330 intermediate risk participants (Framingham risk score of ,5% and ,20% for a coronary event within the next ten years) in the Multi-Ethnic Study of Atherosclerosis (MESA) were ...
Background: Studies have shown that carotid intima-media thickness (CIMT) and ankle-brachial pressure index (ABI) can be used as surrogate markers of coronary artery disease (CAD). However, whether studying the ratio of ABI and CIMT has any added value in predicting CAD when compared to either of them alone, has not been studied. Aims: The aim of the study is to compare CIMT and ABI as surrogate markers for the presence and extent of CAD and to investigate whether studying the ratio of ABI and CIMT has any incremental value in predicting CAD than either of them. Methods: We prospectively enrolled 235 stable, non-ACS patients who underwent CIMT and ABI measurements followed by diagnostic coronary angiography. Results: The mean age of the study population was 56.32 ± 10.14 years. CIMT was significantly higher in the CAD group compared to non-CAD group (0.91 ± 0.22 vs. 0.66 ± 0.15, P ≤ 0.0001). ABI was significantly lower in the CAD group compared to non-CAD group (1.07 ± 0.19 vs. 1.18 ± ...
Conclusions Cumulative vascular risk factor exposure may increase the risk of CMB, especially in deep regions. The apparent paradoxical association of carotid intima-media thickness progression with lower risk of CMB may reflect benefits of intensive vascular risk factor treatment among persons with higher cardiovascular risk and deserves further investigation. If replicated, the results may...
Garovic VD, Milic NM, Weissgerber TL, Mielke MM, Bailey KR, Lahr B, Jayachandran M, White WM, Hodis HN, Miller VM. Carotid Artery Intima-Media Thickness and Subclinical Atherosclerosis in Women With Remote Histories of Preeclampsia: Results From a Rochester Epidemiology Project-Based Study and Meta-analysis. Mayo Clin Proc. 2017 Sep; 92 (9):1328-1340 Epub 2017 Aug 25 ...
TY - JOUR. T1 - The cross-sectional association between uric acid and atherosclerosis and the role of low-grade inflammation: the CODAM study. AU - Wijnands, J.M.A.. AU - Boonen, A.. AU - Dagnelie, P.C.. AU - van Greevenbroek, M.M.J.. AU - van der Kallen, C.J.H.. AU - Ferreira, I.. AU - Schalkwijk, C.G.. AU - Feskens, E.J.M.. AU - Stehouwer, C.D.A.. AU - van der Linden, S.. AU - Arts, I.C.W.. N1 - WOS:000344644800024. PY - 2014. Y1 - 2014. N2 - Objectives. The aims of this study were to investigate (i) associations between uric acid and prevalent cardiovascular disease (CVD), ankle-arm blood pressure index (AAIx) and carotid intima-media thickness (CIMT) in the total population and in predefined subgroups according to glucose metabolism status and (ii) the extent to which these associations are explained by low-grade inflammation. Methods. Cross-sectional analyses were conducted among 530 individuals [60.6% men, mean age 58.9 years (S. D. 6.9), 52.6% normal glucose metabolism (NGM)] at increased ...
Significant evidence has accumulated that psychosocial stress contributes to the etiology and pathogenesis of coronary artery disease. In addition to direct influences through the nervous, endocrine, and immune systems, stress reduces the adoption and maintenance of a healthy lifestyle and adherence to medical care (1). Epidemiological evidence is compelling; several large and international studies have shown that individuals reporting high levels of psychosocial stress have significantly elevated risk of cardiovascular diseases. Most notably, the INTERHEART study demonstrated that among more than 30,000 individuals, those who reported elevated stress had odds ratios for myocardial infarction of 2.5 (2). High work demands and daily stress have also been associated with coronary heart disease (CHD) morbidity and mortality, with carotid artery intima-media thickness progression, and with recurrent events. The most recent addition to this literature was the finding in the prospective Womens Health ...
Therapy-resistant hypertension was present in 9.1% of hypertensive patients with clinically manifest vascular disease and 49.5% had uncontrolled but non-resistant hypertension. Clinical characteristics related to aTRH were higher age, female sex, BMI and waist circumference, diabetes mellitus and duration and multiple locations of vascular disease, lower eGFR and albuminuria. Patients with aTRH had greater carotid intima-media thickness and lower ABI representing greater burden of subclinical vascular damage.. The prevalence of aTRH has been reported to be 9%-13% in the general hypertensive population.20-22 In patients with chronic kidney disease (CKD), known for their high cardiovascular risk, a much higher prevalence of 25%-35% has been found, often using a more stringent BP definition of ,130/80 mm Hg.23-25 Although several reports have shown a higher prevalence of vascular disease in those with aTRH in hypertensive populations,21 22 26-28 the exact aTRH prevalence in patients with clinical ...
The results of this study suggest that HI statin therapy provides a mortality benefit over LMI statin therapy in patients with PAD. This effect was accompanied by a significant reduction in MACE and is consistent with the results of several large randomized controlled trials demonstrating reduced mortality and secondary ischemic events in patients with atherosclerosis of the coronary and cerebral vasculature treated with HI statin therapy.13, 14, 15, 18. The benefit of lowering LDL in preventing MACE has been well described, particularly among patients with coronary atherosclerosis. HI statins exert potent LDL‐lowering effects and may mediate additional benefits through pleiotropic mechanisms leading to atherosclerotic regression and plaque stabilization.19, 20 Indeed, mechanistic studies have demonstrated that HI statin therapy (atorvastatin 80 mg daily) is associated with greater regression of carotid intima-media thickness and coronary atherosclerosis compared with moderate‐intensity ...
American Society of Echocardiography Carotid Intima-Media Thickness Task Force (2008). "Use of Carotid Ultrasound to Identify ... A Consensus Statement from the American Society of Echocardiography Carotid Intima-Media Thickness Task Force Endorsed by the ...
October 2010). Federici M (ed.). "The relationships of markers of cholesterol homeostasis with carotid intima-media thickness ... Differences in cholesterol homeostasis affect the development of early atherosclerosis (carotid intima-media thickness). These ... Media related to Cholesterol at Wikimedia Commons (All articles with dead external links, Articles with dead external links ... ISBN 978-0-7167-2009-6. "The Nobel Prize in Physiology or Medicine, 1964". Nobel Prize, Nobel Media. Espenshade PJ, Hughes AL ( ...
Common carotid intima- media thickness measurements in cardiovascular risk prediction: a meta-analysis. JAMA. 2012 Aug 22;308(8 ...
Cheung YF, Wong SJ, Ho MH (January 2007). "Relationship between carotid intima-media thickness and arterial stiffness in ... Other vascular complications can occur such as increased wall thickness and decreased distensibility of carotid arteries, aorta ... Kawasaki disease may be further classified as a medium-sized vessel vasculitis, affecting medium- and small-sized blood vessels ... Wikimedia Commons has media related to Kawasaki disease. (CS1 Spanish-language sources (es), CS1 Czech-language sources (cs), ...
Riccioni G (2009). "The effect of antihypertensive drugs on carotid intima media thickness: an up-to-date review". Current ... Persistently elevated blood pressure leads to intimal thickening, hyperplasia of the media wall, and hyaline degeneration in ...
Riccioni G (2009). "The effect of antihypertensive drugs on carotid intima media thickness: an up-to-date review". Current ... Springer Science & Business Media. ISBN 978-1-84628-782-4. "Cardiologists in Delhi NCR". Full Details Information. 26 March ...
"Association of specific HLA phenotypes with left ventricular mass and carotid intima-media thickness in hypertensives". Am J ...
"Multi-ethnic genetic association study of carotid intima-media thickness using a targeted cardiovascular SNP microarray". ...
"Genetic variation in the leukotriene pathway and carotid intima-media thickness: a 2-stage replication study". Stroke. 40 (3): ...
July 2007). "Torcetrapib and carotid intima-media thickness in mixed dyslipidaemia (RADIANCE 2 study): a randomised, double- ... "Phase III Carotid B-Mode Ultrasound Study to Compare Anti-Atherosclerotic Effect of Torcetrapib/Atorvastatin to Atorvastatin ... following media and physician criticism, Pfizer had subsequently planned for torcetrapib to be sold independently of Lipitor. A ...
O'Leary DH, Polak JF, Kronmal RA, Manolio TA, Burke GL, Wolfson SK (January 1999). "Carotid-artery intima and media thickness ... Testing for plaque includes a carotid intima-media thickness test, (CIMT), which measures blood flow through the arteries and ... Doneen AL, Bale BF (March 2013). "Carotid intima-media thickness testing as an asymptomatic cardiovascular disease identifier ... "Effect of comprehensive cardiovascular disease risk management on longitudinal changes in carotid artery intima-media thickness ...
Furthermore, rs11556924 has also been associated with altered carotid intima-media thickness in patients with rheumatoid ... "The ZC3HC1 rs11556924 polymorphism is associated with increased carotid intima-media thickness in patients with rheumatoid ...
2010). "Silent cerebral infarction is associated with incident stroke and TIA independent of carotid intima-media thickness". ...
"Relationship of periodontal disease to carotid artery intima-media wall thickness: the atherosclerosis risk in communities ( ...
Provost, E.; Madhloum, N.; Int Panis, L.; De Boever, P.; Nawrot, T.S. (May 2015). "Carotid intima-media thickness, a marker of ... Inventing Pollution: Coal, Smoke, and Culture in Britain since 1800 (2009) Wikimedia Commons has media related to Air pollution ...
Provost EB, Madhloum N, Int Panis L, De Boever P, Nawrot TS (2015). "Carotid intima-media thickness, a marker of subclinical ... carotid IMT (intimal media thickness) measurement by ultrasound, and intravascular ultrasound (IVUS). Examples of physiologic ... "Fine particulate air pollution and the progression of carotid intima-medial thickness: a prospective cohort study from the ... Carotid arteries supply blood to the brain and neck. Marked narrowing of the carotid arteries can present with symptoms such as ...
"Chronic carbon monoxide exposure is associated with the increases in carotid intima-media thickness and C-reactive protein ...
Relation of parity with common carotid intima-media thickness among women of the Study of Health in Pomerania (SHIP). Stroke ... Thyroid function and carotid wall thickness. J Clin Endocrinol Metab 2004;89:2145-2149 Völzke H, Werner A, Wallaschofski H, ... Association between high serum ferritin levels and carotid atherosclerosis in the Study of Health in Pomerania (SHIP). Stroke ...
... and the Carotid Intima-Media Thickness in Patients with Dyslipidemia". Journal of Atherosclerosis and Thrombosis. 22 (11): 1158 ...
... a sub-field of computer-aided translation Intima-media thickness, a measurement of the thickness of artery walls. Also ... Carotid intimal-medial thickness. This disambiguation page lists articles associated with the title IMT. If an internal link ...
"Lysophosphatidylcholine and Carotid Intima-Media Thickness in Young Smokers: A Role for Oxidized LDL-Induced Expression of PBMC ... Intima-media thickness, which is positively correlated with reduced blood flow, was studied in young smokers. Evidence pointed ... due to tobacco smoke's impact on oxidation of retained LDL particles in the intima of a carotid artery. which may have a ...
... as judged by carotid intima-media thickness measurements. Variant alleles involved deletions (one or two) or additions (one, ...
"Coronary artery calcification compared with carotid intima-media thickness in the prediction of cardiovascular disease ...
... and carotid intima-media thickness, in people with primary aldosteronism. In people with hyperaldosteronism due to unilateral ...
2001). "Oxidized LDL and thickness of carotid intima-media are associated with coronary atherosclerosis in middle-aged men: ... The formation of foam cells and their continued accumulation in the intima lead to the formation of fatty streaks. Continued ... Leukocytes migrate to the subendothelial space and aggregate within the intima. In the presence of elevated levels of oxidized ... cells to secrete molecules that cause monocytes to penetrate between the endothelial cells and accumulate in the intima. ...
... established and candidate risk factors in well characterized populations using the intima-media thickness of the common carotid ... Association of postprandial triglyceride and retinyl palmitate responses with asymptomatic carotid artery atherosclerosis in ...
Spence pioneered the use of carotid plaque measurement (as opposed to intima-media thickness) for research and for management ... "Reconstruction of carotid bifurcation hemodynamics and wall thickness using computational fluid dynamics and MRI". Magnetic ... The effect of drug therapies on carotid plaque volume can now be evaluated in a very cost-effective way. Development of ... With Maria Dicicco, RVT, he pioneered the measurement of total plaque area (TPA) in a patient's carotid artery using ultrasound ...
Promising results are found using carotid intima-media thickness scanning (CIMT can be measured by B-mode ultrasonography), B- ... Carotid Intima-media thickness Scan (CIMT can be measured by B-mode ultrasonography) measurement has been recommended by the ... which have supported a direct correlation of Carotid Intima-media thickness (CIMT) with myocardial infarction and stroke risk ... Arterial ultrasound, especially of the carotid arteries, with measurement of the thickness of the artery wall, offers a way to ...
Besides, other features such as intima-media thickness, surface of the plaque and presence of ulceration are also useful in ... computerized algorithms used for evaluation of the intima-media thickness (IMT), a measure of plaque morphology, have helped ... Carotid artery stenosis is a major risk factor for stroke, and risk assessment of atherosclerotic carotid plaques is a critical ... Carotid duplex and contrast-enhanced ultrasound are two of the most common imaging techniques used to evaluate carotid artery ...
Carotid stenosis may occur in patients with atherosclerosis. The intima-media thickness of the carotid artery wall is a marker ... Provost, E; Madhloum, N; Int Panis, L; De Boever, P; Nawrot, T (2015). "Carotid Intima-Media Thickness, a Marker of Subclinical ... carotid artery Right and left common carotid arteries Head and neck anatomy Carotid sheath Carotid sinus Carotid body Carotid ... Wikimedia Commons has media related to Common carotid artery. Anatomy figure: 21:06-01 at Human Anatomy Online, SUNY Downstate ...
Smooth muscle cells migrate from the media to the intima, proliferate, and develop an extracellular matrix made up of collagen ... such as the carotid or femoral arteries. While stability vs. vulnerability cannot be readily distinguished in this way, ... is to use ultrasound to non-invasively measure wall thickness (usually abbreviated IMT) in portions of larger arteries closest ... are absorbed into the intima, past the endothelium lining, some of the LDL-lipoprotein particles become oxidized and this ...
A true aneurysm is one that involves all three layers of the wall of an artery (intima, media and adventitia). True aneurysms ... Similarly, sometimes it is difficult to model the varying wall thickness in small vessels, so researchers treat wall thickness ... The next most common sites of cerebral aneurysm occurrence are in the internal carotid artery. Abdominal aortic aneurysms are ... The neck of the aneurysm is the most at risk due to the combination of a small wall thickness and high wall shear stress. When ...
It consists of three tunics: Tunica media, intima, and external. Systemic arteries are the arteries (including the peripheral ... These are followed by the branches of the aortic arch, namely the brachiocephalic artery, the left common carotid, and the left ... arteries are surrounded by varying thicknesses of smooth muscle which have extensive elastic and inelastic connective tissues. ... The innermost layer, which is in direct contact with the flow of blood, is the tunica intima, commonly called the intima. The ...
... is made up of smooth muscle cells, elastic tissue and collagen. It lies between the tunica intima on the inside ... It is to this coat that the thickness of the wall of the artery is mainly due. In the larger arteries, as the iliac, femoral, ... and carotid, elastic fibers and collagen unite to form lamellæ which alternate with the layers of smooth muscular fibers; these ... The middle coat (tunica media) is distinguished from the inner (tunica intima) by its color and by the transverse arrangement ...
Carotid intima-media thickness (IMT) determined by doppler ultrasonography is a good predictor of the presence and severity of ... Carotid artery intima-media thickness could predict the presence of coronary artery lesions. American journal of hypertension, ... Association of breast artery calcification with coronary artery disease and carotid intima-media thickness in premenopausal ... in young premenopausal women and evaluated the association of BAC with carotid intima-media thickness and standard CAD risk ...
Correlation between the intima-media thickness of the carotid artery and aortic pulse-wave velocity in patients with type 2 ... RESEARCH DESIGN AND METHODS: Aortic distensibility and carotid intimal-media thickness (IMT) were evaluated using carotid- ... Correlation between the intima-media thickness of the carotid artery and aortic pulse-wave velocity in patients with type 2 ... RESULTS: a-PWV and carotid IMT were significantly higher in the patients than in the control subjects in all age-groups (P , ...
Carotid intima-media thickness. Carotid artery ultrasonography and measurement of the intima-media thickness is another area of ... Observational studies have shown that intima-media thickness is an independent marker of cardiovascular risk, but whether it is ... However, with contrast medium and the addition of vasodilators or dobutamine, cMRA can be used to assess myocardial viability ... What is the role of carotid artery ultrasonography in cardiac assessment?. What is the triple rule out (TRO) for cardiac ...
Carotid intima-media thickness. Carotid artery ultrasonography and measurement of the intima-media thickness is another area of ... Observational studies have shown that intima-media thickness is an independent marker of cardiovascular risk, but whether it is ... However, with contrast medium and the addition of vasodilators or dobutamine, cMRA can be used to assess myocardial viability ... What is the role of carotid artery ultrasonography in cardiac assessment?. What is the triple rule out (TRO) for cardiac ...
Receive a carotid intima media thickness test in Allendale, NJ today! ... detects the build-up of fatty substances in your carotid artery wall (atherosclerosis) to evaluate your risk of cardiovascular ... A carotid intima media thickness test - also known as a CIMT scan - ... What Is a Carotid Intima Media Thickness Test?. A carotid intima media thickness test, or CIMT scan, is used to measure the ...
Variability of intima-media thickness of the common carotid arteries in Moscow city population without clinical symptoms of ... Variability of intima-media thickness of the common carotid arteries in Moscow city population without clinical symptoms of ... Variability of intima-media thickness of the common carotid arteries in Moscow city population without clinical symptoms of ... Variability of intima-media thickness of the common carotid arteries in Moscow city population without clinical symptoms of ...
Tewari S, Garg N, Kapoor A, Jain A, Singh U, Godbole MM, Sinha N. Association of common carotid intima-media thickness and ... Association of common carotid intima-media thickness and lipoprotein(a) with coronary artery disease. ... levels in subjects with carotid intimal medial thickness ,0.80 was 26.4 +/- 24.2 mg/dl and in subjects with carotid intimal ... There is a strong correlation between carotid and coronary atherosclerosis and carotid intimal medial thickness is a good ...
... compare carotid intima media thickness (CIMT) of young males who are habitual snorers compared to those who do not snore; 2) to ... compare CIMT between snorers and non-snorers to the intima media thickness (IMT) of the brachial artery, the control, that is ... Brachial and carotid IMT was imaged via ultrasonography; IMT measurements were compared between groups using brachial IMT as ... Conclusion: Results suggest that the vibrations from snoring may contribute to vascular remodeling in the carotid artery, and ...
Anthropometric measurements and blood chemistry analysis, serum CRP levels and carotid intima-media thickness (IMT) ... carotid intima media thickness (IMT), and serum C-reactive protein (CRP) levels in patients with chronic obstructive pulmonary ... in terms of carotid IMT, were found to be higher in COPD patients than in healthy controls. MetS prevalence was observed to ... Carotid IMT was significantly higher in COPD patients than in control group (1.07 ± 0.25 mm and 0.86 ± 0.18 mm, ...
Temporal causal longitudinal associations of high-sensitivity C-reactive protein with carotid intima-media thickness ...
Carotid Intima Media Thickness (CIMT). CIMT. What is it?. Carotid Intima Media Thickness (CIMT) is the most accurate, non- ... A sonographer places an ultrasound probe on the main arteries of your neck (carotids) and obtains an image. The images are ...
"Carotid Intima-Media Thickness" by people in this website by year, and whether "Carotid Intima-Media Thickness" was a major or ... Carotid Intima-Media Thickness*Carotid Intima-Media Thickness. *Carotid Intima Media Thickness ... "Carotid Intima-Media Thickness" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH ( ... Kupetsky-Rincon EA, Li Q, Uitto J. Magnesium reduces carotid intima-media thickness in a mouse model of pseudoxanthoma ...
Carotid-wall intima-media thickness and cardiovascular events. N Engl J Med. 2011 Jul 21. 365(3):213-21. [QxMD MEDLINE Link]. ... Carotid intima-media thickness (IMT), pulse wave velocity (PWV), and the ankle-brachial index (ABI) are widely used noninvasive ... Carotid intima-media thickness (IMT), pulse wave velocity (PWV), and the ankle-brachial index (ABI): Widely used, noninvasive ... Does carotid intima-media thickness regression predict reduction of cardiovascular events? A meta-analysis of 41 randomized ...
Indirect evidence of accelerated atherosclerosis in RA comes from studies measuring carotid artery intima media thickness (CIMT ... Correlation of Intima Media Thickness (As a Marker of Atherosclerosis) With Activity and Duration of Rheumatoid Arthritis Using ... Mythili, M.D (2018); Correlation of Intima Media Thickness (As a Marker of Atherosclerosis) With Activity and Duration of ... Carotid Ultrasound Dr. G. Balaraju, M.D, Dr. R. Nagamani, M.D, Dr. D. Sridhar, M.D, Dr. L. Muralidhar, M.D, Dr. K.S.Amravathi, ...
... and to a control group of normal-weight children using carotid intima-media thickness (CIMT). Participants were 204 obese ... Mean CIMT in control children was 402.97 ± 53.18 μm (left carotid artery) and 377.85 ± 52.47 μm (right carotid artery ... Anthropometric parameters, blood pressure, and a carotid Doppler ultrasound scan were also acquired. The mean CIMT of obese ... right carotid artery). The mean CIMT was not significantly different in MUO and MHO children, whereas it showed a significant ...
... or intima-media thickness (IMT). Our aim was to examine whether these associations are mediated by body mass index (BMI), waist ... We found graded relationships between IGR categories and both major CVD risk factors and carotid/femoral IMT. These ... Carotid and femoral IMT was assessed by ultrasound (n = 496). Age-adjusted levels of the major CVD risk factors worsened ... all more markedly at femoral than carotid levels). The associations between IMT and IFG/IGT or DM (adjusted by age and major ...
Heritability and linkage analysis for carotid intima-media thickness: the family study of stroke risk and carotid ... Mannheim carotid intima-media thickness consensus (2004-2006). An update on behalf of the Advisory Board of the 3rd and 4th ... Heritability of carotid intima-media thickness: a twin study. Atherosclerosis. 2008; 197(2): 814-820.. CrossRefPubMed ... Background: Heart rate (HR), mean arterial pressure (MAP) and carotid intima-media thickness (cIMT) are moderately heritable ...
... thickness, visceral adiposity index (VAI), and with carotid intima-media thickness (cIMT) in patients with T2D and controls. ... The measurement of cIMT and VAT thickness was performed using an Accuvix XQ ultrasound. Circulating levels of CTRP1, CTRP5, and ... From: The circulating levels of CTRP1 and CTRP5 are associated with obesity indices and carotid intima-media thickness (cIMT) ... cIMT carotid intima-media thickness ...
Association of breast artery calcification with coronary artery disease and carotid intima-media thickness in premenopausal ... in young premenopausal women and evaluated the association of BAC with carotid intima-media thickness and standard CAD risk ... Body Mass Index (‎1)‎Breast (‎1)‎Carotid Arteries (‎1)‎Chronic Kidney Disease-Mineral and Bone Disorder (‎1)‎... View MoreDate ...
Increased Carotid Intima-Media Thickness and Endothelial Cell-Specific Molecule-1 (Endocan) Levels in Obese Children ... Early development of insulin resistance (IR) may lead to endothelial dysfunction and increased carotid intima-media thickness ( ...
Carotid intima-media thickness progression as surrogate marker for cardiovascular risk. *Post by: Lena Manuela Tschiderer ... we quantified the association between the intervention effects on carotid intima media thickness (cIMT) progression and the ...
Carotid intima media thickness (CIMT) and carotid plaques (CP) were shown to be independent predictors of mortality in end- ... Keywords: Atherosclerosis, Carotid intima media thickness, Carotid plaque, Continuous ambulatory peritoneal dialysis, Dialysis ... Dialysis Type May Predict Carotid Intima Media Thickness and Plaque Presence in End-Stage Renal Disease Patients ...
There was no significant difference in the reduction of the intima-media thickness (IMT), plaque Crouse score, or plaque area ... and the area and number of bilateral carotid artery plaques before and after 6 months of treatment. The secondary outcomes were ... formula in the treatment of carotid atherosclerotic vulnerable plaques.,i, Methods.,/i, This was a prospective, single-centre, ... may be antiatherosclerotic by strengthening statins to reduce the low-density lipoprotein levels and reducing the carotid ...
Torcetrapib and carotid intima-media thickness in mixed dyslipidaemia (RADIANCE 2 study): a randomised, double-blind trial. * ...
Carotid pulse pressure and intima media thickness are independently associated with cerebral hemodynamic pulsatility in ... Arterial stiffness induced by carotid calcification leads to cerebral gliosis mediated by oxidative stress. J. Hypertens. 36, ... Carotid disease, cognition, and aging: time to redefine asymptomatic disease? *Christina M. Lineback ... Arterial stiffness due to carotid calcification disrupts cerebral blood flow regulation and leads to cognitive deficits. J. Am ...
Correlation between vitamin D and carotid artery intima media thickness in patients with ischemic stroke ... Evaluation of Serum 25-Hydroxyvitamin D as a predictor of carotid intima-media thickness and carotid total plaque area in non- ... Singh AS, Atam V, Patel ML, Chaudhary SC, Sawlani KK, Das L. Carotid intima media thickness as a reflection of generalized ... The correlation of vitamin D and carotid artery intima media thickness in ischemic stroke patients had conflicting results in ...
... we modelled common carotid intima-media thickness, carotid plaque scores, and carotid plaque shadowing as a function of ... we modelled common carotid intima-media thickness, carotid plaque scores, and carotid plaque shadowing as a function of ... we modelled common carotid intima-media thickness, carotid plaque scores, and carotid plaque shadowing as a function of ... we modelled common carotid intima-media thickness, carotid plaque scores, and carotid plaque shadowing as a function of ...
Usefulness of carotid intima-media thickness measurement and peripheral B-mode ultrasound scan in the clinical screening of ... Previous observational studies have shown a relationship between carotid intima-media thickness (IMT) and coronary artery ... Previous observational studies have shown a relationship between carotid intima-media thickness (IMT) and coronary artery ... The mean value of six IMT measurements of the far wall of the common carotid artery was calculated in each patient. The mean ...
  • A Carotid Intima Media Thickness Test (CIMT) is a diagnostic test a healthcare provider may recommend which can help detect atherosclerosis and predict your risk for developing several different cardiovascular health conditions. (cardiology-doctors.com)
  • A carotid intima media thickness test, or CIMT scan , is used to measure the thickness of the inner two layers of the carotid artery-the intima and media-to evaluate the artery's overall health, provide early detection for atherosclerosis and determine your risk for cardiovascular disease and the potential of experiencing a stroke. (cardiology-doctors.com)
  • Carotid Intima Media Thickness (CIMT) is the most accurate, non-invasive screening method available for predicting the risk of heart attack or stroke. (boppskin.com)
  • Indirect evidence of accelerated atherosclerosis in RA comes from studies measuring carotid artery intima media thickness (CIMT). (ijsrp.org)
  • Heart rate (HR), mean arterial pressure (MAP) and carotid intima-media thickness (cIMT) are moderately heritable cardiovascular traits, but the environmental effects on the longitudinal change of their heritability have never been investigated. (viamedica.pl)
  • In this paper - published in Circulation - we quantified the association between the intervention effects on carotid intima media thickness (cIMT) progression and the intervention effect on cardiovascular risk. (i-med.ac.at)
  • Early development of insulin resistance (IR) may lead to endothelial dysfunction and increased carotid intima-media thickness (cIMT) even in childhood. (medeniyet.edu.tr)
  • Carotid intima media thickness (CIMT) and carotid plaques (CP) were shown to be independent predictors of mortality in end-stage renal disease (ESRD) patients. (gazi.edu.tr)
  • Carotid intima-media thickness (cIMT) and carotid distensibility coefficient (cDC) were assessed by high-resolution echo-Doppler analysis and further examined with dedicated hardware. (lww.com)
  • Thus, this study sought to examine the potential moderating effect of race and sexual orientation on the association between adult attachment and carotid-intima media thickness (cIMT), a measure of subclinical cardiovascular disease, among young men. (nyu.edu)
  • and the carotid intima-media thickness (cIMT) is used not only as an early indicator of subclinical organ damage but also a predictor of future atherosclerosis. (biomedcentral.com)
  • The aim of this study is to evaluate serum paraoxanase activities, lipid profiles and carotid intimae media thickness (CIMT) as an early marker of atherosclerosis in healthy man and women.Method: Four hundred healthy volunteers (F/M: 250/150, 19 23 years) included in the study. (endocrine-abstracts.org)
  • The aim of this study was to evaluate carotid intima media thickness (CIMT) and its association with bone mineral density and bone turnover markers as well as inflammation markers in type 2 diabetic male patients.Material-method: 184 type 2 diabetic males (56±8 y) and 85 non-diabetic control subjects (52±7 y) were recruited. (endocrine-abstracts.org)
  • This study aimed to determine diastolic dysfunction and its association with carotis intima media thickness (CIMT) and flow-mediated vasodilation (FMD) in a group of asymptomatic hyperparathyroid patients. (endocrine-abstracts.org)
  • The aim of this study was to determine EFT and its relationship with carotid intima media thickness (CIMT) and flow-mediated vasodilation (FMD) in subclinical and overt hypothyroid patients.Ten patients with overt (Group H) (42.2±15. (endocrine-abstracts.org)
  • Increased carotid intima-media thickness (cIMT) is considered a marker of early-onset atherosclerosis and it seems to predict cardiovascular events both in obese and diabetic subjects. (medsci.org)
  • In addition to the first 2 biomarkers, investigators measured carotid intima-media thickness (cIMT) and ankle brachial index (ABI). (ajmc.com)
  • Smoking status was established during the baseline visit, as was hypertension and carotid intima-media thickness (CIMT). (physiciansweekly.com)
  • We investigated whether low-grade albuminuria (LGA) is independently associated with the carotid intima-media thickness (CIMT) and carotid plaques in normotensive and euglycemic Chinese middle-aged and elderly adults. (eur.nl)
  • Plaque levels can be tested with a non-invasive Carotid Intima Media Thickness (CIMT) ultrasound scan, but few doctors use it and insurance plans don't cover the cost. (betternutrition.com)
  • We concluded that high hsCRP, as defined by JUPITER, was not associated with CAC and was mildly associated with carotid intima-media thickness (cIMT) in the absence of obesity. (hopkinsmedicine.org)
  • In a follow-up analysis from the Kronos Early Estrogen Prevention Study (KEEPS) , low doses of hormone therapy -- both oral and transdermal -- did not change the trajectory of carotid artery intima-media thickness (CIMT) during the 4 years of treatment, according to Virginia Miller, PhD, of the Mayo Clinic in Rochester, Minnesota, and colleagues, in Menopause . (medpagetoday.com)
  • By ultrasonography, carotid intima-media thickness (cIMT), presence of plaques and presence of fatty liver were evaluated. (elsevier.com)
  • Carotid intima media thickness (CIMT), coronary calcium score (CAC), and brachial Flow Mediated Dilation (FMD) were measured. (healthandlongevity.org)
  • The carotid intima-media thickness test (CIMT) is a measure used to diagnose the extent of carotid atherosclerotic vascular disease. (medicalcityhealthcare.com)
  • Associations with carotid plaque burden (A) and cIMT (B) were adjusted for age, sex, and geographic area. (jamanetwork.com)
  • GH deficiency and insufficiency are associated with higher levels of plasminogen activator inhibitor-I levels ( prothrombotic ), carotid intima-media thickness (CIMT) , and loss of circulating CD34+ cells, suggesting endothelial dysfunction . (alphamaleinstitute.com)
  • Methods: Complete risk factor, coronary artery calcification (CAC), and carotid intima media thickness (CIMT) data were available for 2435 participants. (uab.edu)
  • The difference between a Carotid Ultrasound and CIMT ? (revolutionhealth.org)
  • Just the other day I had a patient tell me that he didn't need a CIMT test because he had a carotid ultrasound a year ago. (revolutionhealth.org)
  • Upon further questioning, he had a "conventional" carotid ultrasound and not a CIMT. (revolutionhealth.org)
  • Carotid intima media thickness (CIMT) testing actually measures the blood vessel wall itself. (revolutionhealth.org)
  • Atherosclerosis may cause partial or total blockage of blood flow through arteries in the heart, brain, pelvis, legs, arms or kidneys, and increases your risk of developing such health conditions as coronary heart disease, angina (chest pain), carotid artery disease, peripheral artery disease (PAD) and chronic kidney disease. (cardiology-doctors.com)
  • If your healthcare provider suspects that you have plaque buildup, a carotid ultrasound (an ultrasound of the carotid arteries in your neck) will be recommended. (cardiology-doctors.com)
  • A carotid ultrasound can confirm the existence of plaque in the arteries to determine a treatment course, especially as it relates to managing risk factors causally related with heart disease and stroke. (cardiology-doctors.com)
  • A gel-like substance will be applied to your skin above the site of each carotid artery, after which an ultrasound probe will be gently placed to both sides of your neck (to visualize carotid arteries on both sides of your neck). (cardiology-doctors.com)
  • Aim: To determine borderline values of intima-media thickness (IMT) of the common carotid arteries (CCA) in Moscow sitizens without clinical symptoms of atherosclerosis. (elsevier.com)
  • CCA IMT was measured at ultrasonic scanning of the carotid arteries in high-resolution regimen. (elsevier.com)
  • A sonographer places an ultrasound probe on the main arteries of your neck (carotids) and obtains an image. (boppskin.com)
  • Intima-media thickness (IMT) of peripheral arteries (particularly carotid IMT) can be regarded as a cardiovascular risk factor since it is an independent predictor of CVD morbidity and mortality [ 15 ]. (biomedcentral.com)
  • 368 Italian and Hungarian twins (107 monozygotic, 77 dizygotic) underwent oscillometric measurement and B-mode sonography of bilateral carotid arteries in 2009/2010 and 2014. (viamedica.pl)
  • Carotid intima media thickness (IMT) US uses ultrasound pictures of the carotid arteries to measure the thickness of the two innermost layers (the intima and media ) of the carotid artery walls and to help identify plaque buildup. (radiologyinfo.org)
  • The carotid arteries are the two main arteries that carry oxygen-rich blood from the heart to the brain. (radiologyinfo.org)
  • Carotid artery disease occurs when plaque (a build-up of fat, cholesterol and other substances) collects and forms along the walls of the carotid arteries. (radiologyinfo.org)
  • The American Heart Association guidelines also state that carotid duplex US is a reasonable approach for asymptomatic patients with carotid bruit , an abnormal sound that may indicate turbulent blood flow, detected by a stethoscope when placed on top of the carotid arteries in the neck. (radiologyinfo.org)
  • Atherosclerosis is a disease of large and medium-sized muscular arteries and is characterized by endothelial dysfunction, vascular inflammation, and the buildup of lipids, cholesterol, calcium, and cellular debris within the intima of the vessel wall. (medscape.com)
  • Noncoronary atherosclerosis refers to atherosclerotic disease affecting large and medium-sized noncoronary arteries (eg, extracranial cerebrovascular disease, lower extremity occlusive disease, aneurysmal disease). (medscape.com)
  • [ 24 ] Intima-media thickness (IMT) of the common carotid arteries of hypothyroid patients was decreased after normalization of thyroid function by hormone replacement for 1 year. (medscape.com)
  • We also assessed the extent of fatty plaque buildup in the carotid arteries of African American smokers by a non-invasive procedure called carotid intima media thickness," Oshunbade said. (heart.org)
  • To calculate the rate of progression of atherosclerotic damage, determined by changes in the intima-media thickness (IMT), degree of stenosis and affected area of the carotid arteries, depending on the degree of sensitivity to insulin. (fundacionareces.es)
  • They ascend in the neck, one on each side, and at the level of the upper border of the thyroid cartilage, each divides into two branches, the external (CAROTID ARTERY, EXTERNAL) and internal (CAROTID ARTERY, INTERNAL) carotid arteries. (ucdenver.edu)
  • Carotid intima-media thickness (IMT) determined by doppler ultrasonography is a good predictor of the presence and severity of CAD [3,4]. (who.int)
  • RESEARCH DESIGN AND METHODS: Aortic distensibility and carotid intimal-media thickness (IMT) were evaluated using carotid-femoral aortic pulse-wave velocity (a-PWV) and high-resolution B-mode ultrasonography in 271 patients with type 2 diabetes and 285 age-matched control subjects. (diabetesjournals.org)
  • Subclinical atherosclerosis was diagnosed with carotid ultrasonography. (dovepress.com)
  • Bilateral CIMTs were measured using ultrasonography, and the presence of carotid plaques was assessed. (eur.nl)
  • The proportion of treatment(hypertension, dyslipidemia and diabetes) and intima media thickness in the carotid ultrasonography increased with elevation in pentosidine levels. (nii.ac.jp)
  • Ultrasonography allows for evaluation of brachial artery reactivity (a measure of vessel wall function) and carotid artery intima-media thickness (a measure of anatomy). (medscape.com)
  • To perform a wide variety of biomedical measurements, including carotid ultrasonography and a detailed dental examination, participants were invited to our study center at Keio University Hospital. (biomedcentral.com)
  • Carotid ultrasonography was completed in 458 subjects, which was 99.6% of the clinic visitors (n = 460). (biomedcentral.com)
  • To investigate the safety and efficacy of the Herbal Medicine C-117 (C-117) formula in the treatment of carotid atherosclerotic vulnerable plaques. (hindawi.com)
  • The primary outcomes were the change in stability, the mean change of the plaque Crouse score, and the area and number of bilateral carotid artery plaques before and after 6 months of treatment. (hindawi.com)
  • Rupture of carotid atherosclerosis (CAS) plaques is an important cause of ischemic stroke. (hindawi.com)
  • Studies have shown that, among Chinese symptomatic patients, there were more people with vulnerable carotid artery plaques than those with carotid stenosis (≥50%) [ 4 ]. (hindawi.com)
  • Vascular stent implantation directly covers unstable plaques, and there is a risk of restenosis after vascular stent surgery, while carotid endarterectomy has not been widely available in China. (hindawi.com)
  • In this study the authors evaluated the accuracy of the common carotid IMT measurement in predicting the presence and severity of CAD and the additional information offered by the detection of carotid, iliac, and lower limb plaques. (unipi.it)
  • Prevalence of cardiovascular risk according to the Framingham score, carotid radiofrequency ultrasound (QIMT) and presence of carotid plaques. (anaisdedermatologia.org.br)
  • Carotid plaques were assessed by US. (jrheum.org)
  • Thirty-six percent of patients had carotid plaques. (jrheum.org)
  • After adjusting for conventional CVD risk factors and the glomerular filtration rate (GFR), male and female participants with UACRs in the third tertile for each gender had a 1.696-fold and 1.911-fold increased risk, respectively, of carotid plaques relative to those in the lowest tertiles. (eur.nl)
  • Ankle-brachial index (ABI), carotid artery intima-media thickness and plaques imaging, arterial stiffness and cardiac autonomic neuropathy (CAN) may be considered useful cardiovascular markers, adding predictive value to the usual risk estimates ( 6 , 7 , 8 ). (escardio.org)
  • The carotid artery intima-media thickness (IMT) and carotid plaques (PLQ) were measured by B-mode ultrasound. (biomedcentral.com)
  • After multiple adjustment, the odds ratios (ORs) were substantially higher risk for carotid plaques (OR 1.77 for 1 SD decrease in osteocalcin, 95% CI 1.23-2.76, p=0.005). (biomedcentral.com)
  • ABSTRACT This study investigated whether breast arterial calcification (BAC) has an association with coronary artery diseases (CAD) in young premenopausal women and evaluated the association of BAC with carotid intima-media thickness and standard CAD risk factors. (who.int)
  • There are three accepted essential elements in the pathogenesis of atherosclerosis: lipoprotein serum concentration, endothelial permeability and binding of lipoproteins in the arterial intima. (bmj.com)
  • Arterial diameters and cross-sectional areas, and arterial wall thickness were measured offline. (ugent.be)
  • Regional arterial wall stiffness of the aorta and common carotid artery were assessed using pulse wave velocity, while lumen area/diameter change, strain, compliance and distensibility were calculated to assess local arterial wall stiffness. (ugent.be)
  • All arterial dimensions and intima-media thickness of the common carotid artery were significantly larger in old horses. (ugent.be)
  • A significantly higher local arterial wall stiffness was found for the aorta and the caudal common carotid artery in older horses. (ugent.be)
  • MR-pro-ADM levels were assessed in 4155 individuals who underwent evaluation of carotid intima-media thickness and arterial rigidity (reflection index and stiffness index). (eur.nl)
  • Non-invasive assessment of atherosclerotic abnormalities through imaging in both high risk and low risk populations by measurement of carotid intima-media thickness, carotid plaque, arterial stiffness, coronary calcifications, coronary stenosis and their progression over time are major topics in his studies. (umcutrecht.nl)
  • Levels, carotid intima-media thickness (IMT), arterial reactivity, and left medical Education and Research. (awingsoft.com)
  • Elevated brachial arterial pressures predict CV events and mortality in addition to structural changes (e.g., left ventricular hypertrophy, carotid intima-media thickness and reduced glomerular filtration rate). (atcormedical.com)
  • Assessment of subclinical atherosclerosis by carotid intima media thickness: technical issues. (ijmedicine.com)
  • Cognitive performance is lower among individuals with overlap syndrome than in individuals with COPD or obstructive sleep apnea alone: association with carotid artery stiffness. (ucdenver.edu)
  • [ 23 ] Patients with hypothyroidism have been reported to have greater radial wall thickness and compliance than euthyroid healthy age- and sex-matched controls. (medscape.com)
  • METHODS: From the Atherosclerosis Risk in Communities (ARIC) Study, 323 cases with carotid intima-media wall thickness above the 90th percentile (measured with B-mode ultrasound) were matched 1:1 with controls without atherosclerosis. (lu.se)
  • Measurements of common carotid artery intima-media thickness (CCA-IMT) and brachial artery endothelium-dependent, flow-mediated dilatation (BA-FMD) were performed at randomisation and after 6, 12 and 18 months. (clinicaltrials.gov)
  • Among 6553 participants ages 45-84 years without prior cardiovascular disease in the Multi-Ethnic Study of Atherosclerosis, coronary artery calcium score was assessed for cardiovascular risk prediction beyond the Framingham predictors in those with ( n =1284) and without CKD and contrasted with carotid intima-media thickness and ankle-brachial index (two other measures of subclinical atherosclerosis). (asnjournals.org)
  • Compared with inclusion of carotid intima-media thickness or ankle-brachial index, inclusion of the coronary artery calcium score led to greater increases in C statistic for predicting cardiovascular disease and net reclassification improvement. (asnjournals.org)
  • Brachial and carotid hemodynamic response to hot water immersion in men and women. (ucdenver.edu)
  • Healthy volunteers were evaluated by coronary computed tomography angiography (CTA) as well as carotid and brachial artery ultrasound. (wineinformationcouncil.eu)
  • IMSEAR at SEARO: Association of common carotid intima-media thickness and lipoprotein(a) with coronary artery disease. (who.int)
  • Tewari S, Garg N, Kapoor A, Jain A, Singh U, Godbole MM, Sinha N. Association of common carotid intima-media thickness and lipoprotein(a) with coronary artery disease. (who.int)
  • After accounting for demographic characteristics, SEP, and traditional CVD risk factors, we modelled common carotid intima-media thickness, carotid plaque scores, and carotid plaque shadowing as a function of occupational category, physical hazard exposure, physical activity on the job, interpersonal stress, job control and job demands. (mssm.edu)
  • The mean value of six IMT measurements of the far wall of the common carotid artery was calculated in each patient. (unipi.it)
  • B-mode ultrasound scan including common carotid IMT measurement and peripheral plaque detection may be of clinical value in the screening of patients with CAD. (unipi.it)
  • Aim: To determine the clinical and dietary predictors of common carotid artery intima media thickness (CCA IMT) in a cohort of subjects with type 1 and type 2 diabetes. (edu.au)
  • The Testosterone's Effects on Atherosclerosis Progression in Aging Men (TEAAM) Trial evaluated the impact of increasing testosterone concentrations on progression of atherosclerosis as determined by common carotid artery intima-media thickness and coronary artery calcium. (bmj.com)
  • Halpern AL, Burton CR, Steward LT. Ligation of common carotid artery after penetrating neck trauma. (ucdenver.edu)
  • Correlation between the intima-media thickness of the carotid artery and aortic pulse-wave velocity in patients with type 2 diabetes. (diabetesjournals.org)
  • analysis of echocardiography data for aortic valve stenosis, carotid duplex ultrasound for atherosclerosis burden, and exercise SPECT imaging in selected cases of suspected coronary heart disease (CHD) will be performed during the baseline visit. (centerwatch.com)
  • Both aortic and carotid pulse wave velocities were higher in older horses compared with younger horses. (ugent.be)
  • Vitamin D deficiency is associated with subclinical carotid atherosclerosis: the Northern Manhattan Study. (ijmedicine.com)
  • However, the thickness of the innermost layers of the carotid artery walls is an independent marker for atherosclerosis. (radiologyinfo.org)
  • The noninvasive test measures the thickness of the inner two layers of the carotid artery and alerts physicians to any thickening while the patients are still asymptomatic. (medicalcityhealthcare.com)
  • CONCLUSIONS: There is a strong correlation between carotid and coronary atherosclerosis and carotid intimal medial thickness is a good predictor of presence and extent of coronary artery disease. (who.int)
  • The correlation of vitamin D and carotid artery intima media thickness in ischemic stroke patients had conflicting results in different parts of the world. (ijmedicine.com)
  • Correlation analysis found an inverse relationship between serum vitamin D level and carotid-IMT in ischemic stroke patients. (ijmedicine.com)
  • To compare increased cardiovascular risk in psoriasis patients receiving two types of treatments: Methotrexate and tumor necrosis factor inhibitor and to evaluate the correlation between the Framingham score and quantitative intima media thickness. (anaisdedermatologia.org.br)
  • In hypertensive subjects, a significant positive correlation was seen between platelets and intima media thickness (β = 0.19, p = 0.008), whereas no significant correlation was seen between platelet count and the natural log of the number of circulating CD34-positive cells (β = 0.11, p = 0.119). (elsevier.com)
  • Atheroma - Classification and external resources Atherosclerotic plaque from a carotid endarterectomy specimen. (en-academic.com)
  • Serum 25-hydroxyvitamin concentration in subclinical carotid atherosclerosis. (ijmedicine.com)
  • This study examines associations of occupational category as an SEP marker and selected occupational exposures with progression of the subclinical carotid artery disease. (mssm.edu)
  • A total of 669 (46.1%) patients were diagnosed with subclinical carotid atherosclerosis. (dovepress.com)
  • The carotid IMT and a-PWV were significantly correlated with age in both the patients with type 2 diabetes and control subjects. (diabetesjournals.org)
  • To investigate the association of serum osteocalcin with carotid atherosclerosis in patients with type 2 diabetes. (biomedcentral.com)
  • Serum osteocalcin levels is an independent risk factor for carotid atherosclerosis in patients with type 2 diabetes. (biomedcentral.com)
  • To better evaluate the possible role of serum osteocalcin in the development of diabetic macrovascular diseases, we examined the association of serum osteocalcin levels and development of carotid atherosclerosis in type 2 diabetes. (biomedcentral.com)
  • 3 In 2011, 42 carotid endarterectomy specimens were analysed for oral pathogen DNA. (bmj.com)
  • This study aimed to identify direct associations between the WSS topological skeleton and markers of vascular disease from real-world clinical longitudinal data of long-term restenosis after carotid endarterectomy (CEA). (polimi.it)
  • Studies show that carotid plaque volumes more accurately estimate a patient's risk of coronary artery disease as well as stroke. (cardiology-doctors.com)
  • BACKGROUND: Carotid artery intimal medial thickness is a simple, non-invasive and reproducible clinical tool to evaluate atherosclerosis and predict coronary artery disease. (who.int)
  • This study evaluated the association of carotid intimal medial thickness and lipoprotein(a) with coronary artery disease. (who.int)
  • Carotid intimal medial thickness and lipoprotein(a) in conjoint can predict coronary artery disease reliably. (who.int)
  • Previous observational studies have shown a relationship between carotid intima-media thickness (IMT) and coronary artery disease (CAD). (unipi.it)
  • Left untreated, carotid artery disease increases the risk for stroke . (radiologyinfo.org)
  • Carotid IMT US is not universally accepted as a means of screening for carotid artery disease. (radiologyinfo.org)
  • Which Is the Ideal Marker for Early Atherosclerosis in Obstructive Sleep Apnea (OSA) - Carotid Intima-Media Thickness or Mean Platelet Volume? (medscimonit.com)
  • The plaque buildup in these 2 layers can become significant far before it would show up on a carotid doppler ultrasound. (revolutionhealth.org)
  • The aim of this study is to investigate the prevalence of metabolic syndrome (MetS), carotid intima media thickness (IMT), and serum C-reactive protein (CRP) levels in patients with chronic obstructive pulmonary disease (COPD), and the possible relationships among them. (biomedcentral.com)
  • We thank Dr. Kawada for his interest in our recent article, in which we reported a positive association between metabolic syndrome (MetSyn) and carotid intima media thickness (IMT) in female police officers. (cdc.gov)
  • Anthropometric measurements and blood chemistry analysis, serum CRP levels and carotid intima-media thickness (IMT) measurements were performed in all the study population. (biomedcentral.com)
  • This study aimed to investigate the relationship between serum vitamin D level and carotid artery intima-media thickness in ischemic stroke patients. (ijmedicine.com)
  • Measurements of serum vitamin D concentration and Carotid-IMT were made by electrochemiluminescence immunoassay and B-mode ultrasound, respectively. (ijmedicine.com)
  • Evaluation of Serum 25-Hydroxyvitamin D as a predictor of carotid intima-media thickness and carotid total plaque area in non-smoker: The tromsø study. (ijmedicine.com)
  • Association between serum sialic acid concentration and carotid atherosclerosis measured by B-mode ultrasound. (lu.se)
  • Serum sialic acid, plasma LDL and HDL cholesterol, serum insulin concentrations, blood pressure, antihypertensive medication use, and smoking status were used to assess the independent contribution of the sialic acid level to carotid atherosclerosis. (lu.se)
  • Serum Ferritin Relates to Carotid Intima-Media Thickness in Offspring of Fathers With Higher Serum Ferritin Levels. (idibgi.org)
  • Daily marital interaction quality and carotid artery intima medial thickness in healthy middle aged adults. (pepperdine.edu)
  • Singh AS, Atam V, Patel ML, Chaudhary SC, Sawlani KK, Das L. Carotid intima media thickness as a reflection of generalized atherosclerosis is related to body mass index in ischemic stroke patients. (ijmedicine.com)
  • Direct Carotid Artery Puncture for Thrombectomy in Pediatric Stroke. (ucdenver.edu)
  • It's performed with an ultrasound of your carotid artery walls, which provides valuable information in assessing your risk of stroke and heart disease. (jivahealth.com)
  • Conclusion: Results suggest that the vibrations from snoring may contribute to vascular remodeling in the carotid artery, and may be an early mechanism contributing to the development of endothelial dysfunction, and early subclinical sign of CVD risk in those at high risk for OSA. (jmu.edu)
  • Intima-media thickness was not related to ADM single nucleotide polymorphisms or expression.Conclusions: These results support an involvement of the ADM gene in the modulation of peripheral vascular tone. (eur.nl)
  • The carotid doppler ultrasound requires a sonographer trained in vascular ultrasound which will increase the cost of the test. (revolutionhealth.org)
  • The mean carotid intimal medial thicknesses in patients with triple vessel, double vessel and single vessel disease were 0.96 +/- 0.12 mm, 0.84 +/- 0.11 mm and 0.78 +/- 0.13 mm, respectively (p=0.05). (who.int)
  • Personalized computational hemodynamic simulations were performed on a cohort of 13 carotid models pre-CEA and at 1 month after CEA. (polimi.it)
  • Secondary outcomes showed a reduction in blood pressure, A1c levels, carotid intima-media thickness, and better lipid profiles in all patients who underwent periodontal treatment. (medscape.com)
  • Multiple regression analysis in all subjects showed that age, diabetic state, and cigarette smoking were independently common risk factors for the increase in carotid IMT and a-PWV. (diabetesjournals.org)
  • Conclusions: These results suggest that the UACR is independently associated with carotid atherosclerosis in normotensive and euglycemic Chinese individuals and that even when well below the current microalbuminuria threshold, LGA contributes to the risk of atherosclerosis. (eur.nl)
  • CONCLUSION: The sialic acid level is correlated with the presence of carotid atherosclerosis, independently of major cardiovascular disease risk factors. (lu.se)
  • 25-Hydroxyvitamin D and parathyroid hormone are not associated with carotid intima-media thickness or plaque in the multi-ethnic study of atherosclerosis. (hopkinsmedicine.org)
  • Background Elevated IMT (intima-media thickness) in carotids can be used as an early on atherosclerosis marker also to evaluate the threat of cardiovascular complications. (healthweeks.com)
  • The measurement of carotid IMT and the diagnosis of MetS may enable us to use these parameters in COPD patients to predict atherosclerosis and CVD, pathological conditions that can seriously affect the outcome. (biomedcentral.com)
  • A measurement of the thickness of the carotid artery walls. (jefferson.edu)
  • Technology Insight: ultrasound measurement of carotid plaque-patient management, genetic research, and therapy evaluation. (ijmedicine.com)
  • Gates PE, Gurung A, Mazzaro L, Aizawa K, Elyas S, Strain WD, Shore AC, Shandas R. Measurement of Wall Shear Stress Exerted by Flowing Blood in the Human Carotid Artery: Ultrasound Doppler Velocimetry and Echo Particle Image Velocimetry. (ucdenver.edu)
  • After an initial visit for signature of informed consent form and medical history registration, all volunteers undergo biochemical analysis, echocardiography, carotid ultrasound, ophthalmologist visit, dual x-ray absorptiometry, coronary artery calcium score, polyneuropathy assessment, advanced glycation end-products reader, and ambulatory blood pressure monitoring. (researchsquare.com)
  • These associations remained significant after further adjustments for large-vessel atherosclerosis (carotid intima-media thickness, coronary artery calcium, and ankle-arm index). (elsevier.com)
  • We investigated whether a lifestyle of regular long-term RW consumption is associated with changes in coronary plaque burden, calcium score, carotid intima/media thickness, endothelial function, and metabolic variables, compared with alcohol abstinence. (wineinformationcouncil.eu)
  • The carotid doppler ultrasound is looking at blood flow through the carotid artery. (revolutionhealth.org)
  • The carotid doppler ultrasound does not look at the health of the artery, only if it has plaque and to what degree. (revolutionhealth.org)
  • So, don't walk away from a carotid doppler ultrasound with a false sense of security. (revolutionhealth.org)
  • Association of inflammatory markers and carotid intima-media thickness with the risk of cardiovascular events in high-risk patients. (nih.gov)
  • One hundred and fifty consecutive patients were subjected to coronary angiography and carotid, iliac, and lower limb ultrasound scan. (unipi.it)
  • Early markers of atherogenesis, in terms of carotid IMT, were found to be higher in COPD patients than in healthy controls. (biomedcentral.com)
  • In the light of the above mentioned observations, this study aims to investigate the common cardiovascular risk factors like MetS, carotid IMT - as an indicator of carotid atherosclerosis - and CRP levels and the relationships between these parameters in COPD patients. (biomedcentral.com)
  • We investigated, in patients with mild-to-moderate chronic kidney disease (CKD), the effect of an oxidative-stress-lowering therapy with pravastatin, vitamin E and homocysteine-lowering on carotid intima-media thickness and endothelial function (two strong surrogate markers of cardiovascular risk), and renal function. (clinicaltrials.gov)
  • Carotid artery ultrasound (US) was found useful in identifying high CV-risk patients with inflammatory arthritis. (jrheum.org)
  • We assessed the effect of carotid US assessments on the CV risk stratification of patients with SLE. (jrheum.org)
  • Following carotid US assessment, 32% of the patients were reclassified as very high risk. (jrheum.org)
  • Reclassification into a very high-risk category is frequent after carotid US assessments in patients with SLE. (jrheum.org)
  • RÉSUMÉ Cette étude a cherché à déterminer si la calcification des artères mammaires (CAM) avait un lien avec les coronaropathies chez la femme préménopausée et à évaluer son association à l'épaisseur intima-média carotidienne et aux facteurs de risque de coronaropathie courants. (who.int)
  • The combined information offered by IMT measurements and peripheral (carotid, iliac, and lower limb) plaque detection was then used to obtain the best multivariate regression model able to predict CAD status. (unipi.it)
  • But in neither study was Lp(a) in youth associated with increased carotid artery intima-media thickness (IMT) in adulthood. (medscape.com)
  • Non-HDL Cholesterol Levels in Childhood and Carotid Intima-Media Thickness in Adulthood. (ucdenver.edu)