Benign paraganglioma at the bifurcation of the COMMON CAROTID ARTERIES. It can encroach on the parapharyngeal space and produce dysphagia, pain, and cranial nerve palsies.
A small cluster of chemoreceptive and supporting cells located near the bifurcation of the internal carotid artery. The carotid body, which is richly supplied with fenestrated capillaries, senses the pH, carbon dioxide, and oxygen concentrations in the blood and plays a crucial role in their homeostatic control.
Traumatic injuries to the VAGUS NERVE. Because the vagus nerve innervates multiple organs, injuries in the nerve fibers may result in any gastrointestinal organ dysfunction downstream of the injury site.
Traumatic injuries to the HYPOGLOSSAL NERVE.
A syndrome associated with defective sympathetic innervation to one side of the face, including the eye. Clinical features include MIOSIS; mild BLEPHAROPTOSIS; and hemifacial ANHIDROSIS (decreased sweating)(see HYPOHIDROSIS). Lesions of the BRAIN STEM; cervical SPINAL CORD; first thoracic nerve root; apex of the LUNG; CAROTID ARTERY; CAVERNOUS SINUS; and apex of the ORBIT may cause this condition. (From Miller et al., Clinical Neuro-Ophthalmology, 4th ed, pp500-11)
Small clusters of chemoreceptive and supporting cells located near the ARCH OF THE AORTA; the PULMONARY ARTERIES; and the CORONARY ARTERIES. The aortic bodies sense PH; CARBON DIOXIDE; and OXYGEN concentrations in the BLOOD and participate in the control of RESPIRATION. The aortic bodies should not be confused with the PARA-AORTIC BODIES in the abdomen (which are sometimes also called aortic bodies).
A neural crest tumor usually derived from the chromoreceptor tissue of a paraganglion, such as the carotid body, or medulla of the adrenal gland (usually called a chromaffinoma or pheochromocytoma). It is more common in women than in men. (Stedman, 25th ed; from Segen, Dictionary of Modern Medicine, 1992)
A relatively rare, usually benign neoplasm originating in the chemoreceptor tissue of the CAROTID BODY; GLOMUS JUGULARE; GLOMUS TYMPANICUM; AORTIC BODIES; and the female genital tract. It consists histologically of rounded or ovoid hyperchromatic cells that tend to be grouped in an alveolus-like pattern within a scant to moderate amount of fibrous stroma and a few large thin-walled vascular channels. (From Stedman, 27th ed)
A flavoprotein containing oxidoreductase that catalyzes the dehydrogenation of SUCCINATE to fumarate. In most eukaryotic organisms this enzyme is a component of mitochondrial electron transport complex II.
Either of the two principal arteries on both sides of the neck that supply blood to the head and neck; each divides into two branches, the internal carotid artery and the external carotid artery.
Cells specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptor cells may monitor external stimuli, as in TASTE and OLFACTION, or internal stimuli, such as the concentrations of OXYGEN and CARBON DIOXIDE in the blood.
Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3)
Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)

Familial carotid body tumors: a closer look. (1/77)

PURPOSE: A family spanning three generations with a history of familial carotid body tumors (CBTs) was studied, and previously proposed hypotheses of tumor characteristics and genetic mode of transmission were addressed. METHODS: Clinically occult lesions in adult subjects were detected by means of high-resolution computed tomography. RESULTS: A 60% incidence of bilaterality of CBTs associated with multiple paragangliomas was noted in the family studied. The genetic mode for CBTs in this family was not simple autosomal dominant transmission and appeared to be paternally directed with complete penetrance. CONCLUSION: In patients with familial CBTs, high-resolution computed tomography is recommended for early screening as a means of prompting diagnosis and definitive treatment, an approach that minimizes morbidity and facilitates surgical excision.  (+info)

Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma. (2/77)

Hereditary paraganglioma (PGL) is characterized by the development of benign, vascularized tumors in the head and neck. The most common tumor site is the carotid body (CB), a chemoreceptive organ that senses oxygen levels in the blood. Analysis of families carrying the PGL1 gene, described here, revealed germ line mutations in the SDHD gene on chromosome 11q23. SDHD encodes a mitochondrial respiratory chain protein-the small subunit of cytochrome b in succinate-ubiquinone oxidoreductase (cybS). In contrast to expectations based on the inheritance pattern of PGL, the SDHD gene showed no evidence of imprinting. These findings indicate that mitochondria play an important role in the pathogenesis of certain tumors and that cybS plays a role in normal CB physiology.  (+info)

Bilateral carotid body paraganglioma: case report. (3/77)

CONTEXT: Surgical treatment of carotid body paragangliomas is a challenge to the surgeon because of the large vascularization of the tumor, involvement of the carotid vessels and the close anatomical relationship with the cranial nerves. CASE REPORT: A 63-year-old patient was submitted to resection of two carotid body paraganglioma tumors found in the right-side and left-side carotid bodies at the bifurcation of the common carotid arteries. Two surgeries were performed at different times and neither of them presented any morbidity. Arteriography was fundamental for diagnosis of the small, asymptomatic tumor on the right side. DESIGN: Case Report  (+info)

Baroreflex failure syndrome after bilateral excision of carotid body tumors: an underestimated problem. (4/77)

Carotid body tumors (CBTs) are relatively rare paragangliomas that develop from neural crest cells at the bifurcation of the common carotid artery. They are generally slow growing and benign. Excision is currently considered the treatment of choice, although vascular and especially neural injuries are still relatively frequent in patients with large or bilaterally resected tumors. The baroreflex failure syndrome (BFS) has recently been identified as a severe, rarely recognized, and certainly underestimated complication after the bilateral excision of CBTs. The present report describes a case of a bilateral CBT followed by BFS and reviews the experiences reported in the literature. In light of the low incidence of malignancy of these tumors, their biologic behavior, their very high rate of cranial nerve palsy, and the occurrence of BFS in bilaterally resected paragangliomas, the current practice of bilaterally removing these tumors is questioned.  (+info)

Power Doppler scanning in the diagnosis of carotid body tumors. (5/77)

The aim of this work was to show contribution of power Doppler imaging in the diagnosis of the carotid body tumors. Six patients with a nontender mass beneath the mandibular angle were evaluated with gray scale and power Doppler sonography. Well-defined, solid, weakly hyperechoic masses were noted on gray scale sonography in the carotid bifurcation. Power Doppler sonography showed abundant flow, characterized as an intense blush, throughout the entire tumor in all patients. We believe that invasive and expensive diagnostic modalities are not necessary to evaluate carotid body tumors. Gray scale sonography and power Doppler imaging are sufficient for primary diagnosis of carotid body tumors.  (+info)

Malignant carotid body tumor: a case report. (6/77)

Carotid body tumors (CBTs) have an unpredictable history with no correlation between histology and clinical behavior. Of reported cases since 1891, local and distant metastases appear in approximately 10% of cases and remain the hallmark of malignancy. Currently, there are not enough data to support a single treatment regimen for malignant CBTs. The reported case demonstrates some unanswered issues with regard to malignant CBTs to include lymph node dissection, the need for carotid resection, and the role of radiation therapy. A 46-year-old pathologist underwent a resection of a Shamblin I CBT, to include jugular lymph node sampling, without complication. There was lymph node involvement, and tumor cells were found on the margins of the pathologic specimen. Subsequent carotid resection with reversed interposition saphenous vein graft and modified neck dissection were performed again without complication. Follow-up at 4 years has been uneventful. Diagnosis of CBTs with the use of magnetic resonance angiography, magnetic resonance imaging, color flow duplex scanning, and the role of arteriography are reviewed. The current treatment options are discussed with reference to primary lymph node sampling, carotid resection, and neck dissection in malignant cases. This case demonstrates that the unpredictable nature of CBTs and their malignant potential warrant aggressive initial local treatment to include jugular lymph node sampling and complete tumor resection.  (+info)

Long-term effects of carotid sinus denervation on arterial blood pressure in humans. (7/77)

BACKGROUND: After experimental carotid sinus denervation in animals, blood pressure (BP) level and variability increase markedly but normalize to preoperative levels within 10 to 14 days. We investigated the course of arterial BP level and variability after bilateral denervation of the carotid sinus baroreceptors in humans. METHODS AND RESULTS: We studied 4 women (age 41 to 63 years) who were referred for evaluation of arterial baroreflex function because of clinical suspicion of carotid sinus denervation attributable to bilateral carotid body tumor resection. The course of BP level and variability was assessed from repeated office and 24-hour ambulatory measurements (Spacelabs/Portapres) during 1 to 10 years of (retrospective) follow-up. Rapid cardiovascular reflex adjustments to active standing and Valsalva's maneuver were assessed. Office BP level increased from 132/86 mm Hg (range, 118 to 148/80 to 92 mm Hg) before bilateral surgery to 160/105 mm Hg (range, 143 to 194/90 to 116 mm Hg) 1 to 10 years after surgery. During continuous 24-hour noninvasive BP recording (Portapres), a marked BP variability was apparent in all 4 patients. Initial symptomatic hypotension on change to the upright posture and abnormal responses to Valsalva's maneuver were observed. CONCLUSIONS: Acute carotid sinus denervation, as a result of bilateral carotid body tumor resection, has a long-term effect on the level, variability, and rapid reflex control of arterial BP. Therefore, in contrast to earlier experimental observations, the compensatory ability of the baroreceptor areas outside the carotid sinus seems to be of limited importance in the regulation of BP in humans.  (+info)

Baroreflex control of muscle sympathetic nerve activity after carotid body tumor resection. (8/77)

Bilateral carotid body tumor resection causes a permanent attenuation of vagal baroreflex sensitivity. We retrospectively examined the effects of bilateral carotid body tumor resection on the baroreflex control of sympathetic nerve traffic. Muscle sympathetic nerve activity was recorded in 5 patients after bilateral carotid body tumor resection (1 man and 4 women, 51+/-11 years) and 6 healthy control subjects (2 men and 4 women, 50+/-7 years). Baroreflex sensitivity was calculated from changes in R-R interval and muscle sympathetic nerve activity in response to bolus injections of phenylephrine and nitroprusside. In addition, sympathetic responses to the Valsalva maneuver and cold pressor test were measured. The integrated neurogram of patients and control subjects contained a similar pattern of pulse synchronous burst of nerve activity. Baroreflex control of both heart rate and sympathetic nerve activity were attenuated in patients as compared with control subjects [heart rate baroreflex sensitivity: 3.68+/-0.93 versus 11.61+/-4.72 ms/mm Hg (phenylephrine, P=0.011) and 2.53+/-1.36 versus 5.82+/-1.94 ms/mm Hg (nitroprusside, P=0.05); sympathetic baroreflex sensitivity: 3.70+/-2.90 versus 7.53+/-4.12 activity/100 beats/mm Hg (phenylephrine, P=0.10) and 3.93+/-4.43 versus 15.27+/-10.03 activity/100 beats/mm Hg (nitroprusside, P=0.028)]. The Valsalva maneuver elicited normal reflex changes in muscle sympathetic nerve activity, whereas heart rate responses were blunted in the patients with bilateral carotid body tumor resection. Maximal sympathetic responses to the cold pressor test did not differ between the two groups. Denervation of carotid sinus baroreceptors as the result of bilateral carotid body tumor resection produces chronic impairment of baroreflex control of both heart rate and sympathetic nerve activity. During the Valsalva maneuver, loss of carotid baroreflex control of heart rate is less well compensated for by the extra carotid baroreceptors than the control of muscle sympathetic nerve activity.  (+info)

NOTOC__ {{Carotid body tumor}} {{CMG}}; {{AE}} {{Sahar}} {{MV}} ==Overview== If left untreated, patients with [[carotid body]] [[tumor]] may progress to develop [[Cranial nerve disease,cranial nerve dysfunction]], [[airway obstruction]], and [[malignant]] [[transformation]] of the [[tumor]]. [[Prognosis]] is generally good, and the 10-year [[survival rate]] of patients is approximately 50%. ==Natural History, Complications, and Prognosis== ===Natural History=== *The [[symptoms]] of [[carotid body]] [[tumor]] usually develop in the fifth decade of life and start with [[symptoms]] such as [[asymptomatic]] [[mass]] in the [[anterior triangle of the neck]].,ref name=LeeOh2006>{{cite journal,last1=Lee,first1=Ki Yeol,last2=Oh,first2=Yu-Whan,last3=Noh,first3=Hyung Jun,last4=Lee,first4=Yu Jin,last5=Yong,first5=Hwan-Seok,last6=Kang,first6=Eun-Young,last7=Kim,first7=Kyeong Ah,last8=Lee,first8=Nam Joon,title=Extraadrenal Paragangliomas of the Body: Imaging Features,journal=American Journal of ...
The carotid body is a small structure weighing 12 mg located in the adventitia of carotid artery bifurcation acting as a chemoreceptor. Carotid body tumour (CBT); formerly known as chemodectoma is a rare, highly vascular, mostly benign tumour arising from the paraganglia of carotid body; hence, the name (carotid paraganglioma). The high vascularity and proximity to cranial nerves and major vessels make this tumour a surgical challenge. Abundant literature has been written about CBT in the last century with a continuous debate regarding its etiology, natural history, biological behavior, proper technique of excision, and the morbidity and mortality associated with its resection. The purpose of this review article is to simplify understanding the basic and clinical aspects of this challenging neoplasm.
From these findings, several perioperative anesthetic implications2 can be anticipated during resection. First, because a carotid body paraganglioma is a neuroendocrine tumor, release of catecholamines or association with a pheochromocytoma should be suspected. Endocrine evaluation will determine if preoperative α-blockade is needed to prevent intraoperative hypertensive crises. The tumor blush from the neoplastic vascular proliferation is indicative of an increased risk of profuse hemorrhage. Consequently, tumor biopsy is contraindicated. Preoperative tumor embolization should be considered3 and the need for rapid blood transfusion anticipated. The ICA plaque may lead to cerebrovascular accidents by obstruction of cerebral blood flow and by embolic stroke from plaque dislodgement during ICA dissection. Finally, tumor invasion may lead to carotid sinus hypersensitivity, and carotid sinus manipulation may precipitate severe bradycardia ...
Results: Among the 27 patients 63% were women, 83% were asymptomatic, and the mean age was 50 years (range 21-79). None of the tumors were hormonally active, mean size was 3.2 centimeters (range 1.6 - 5.0 cm), and the Shamblin class distribution was: 9% type I, 48% type II, and 43% type III. Men were found to have significantly larger tumors on presentation (4.1 cm vs 2.8 cm, p=0.001), though this did not correlate to an increased complication rate. Preoperative embolization was performed in 8 patients, which did not correlate with tumor size. All tumors were completely resected with a mean estimated blood loss of 217 mL (range 5 1000 mL) and no evidence of metastatic disease. The 30-day death, stroke, and cranial nerve injury rates were 0%, 9%, and 27%, respectively. Cranial nerve injuries included 18% vagus, 4.5% hypoglossal, 4.5% facial, and 4.5% glossopharyngeal, but no permanent injuries. Mean length of stay was 2.7 days (range 1-7 days). At a mean follow-up of 12 months (range 1-63 ...
CT of the neck is helpful for diagnosis and can identify any local lymph node enlargement or bony erosions. Additionally, MR can help determine the relationship of the tumor with respect to the carotid vessels and other neck structures and if there are multiple paragangliomas present. A classic finding of the carotid body tumor is splaying of the internal and external carotid arteries. On both enhanced CT and MR, the carotid body tumors and other paragangliomas are intensely enhancing due to their extensive vascularity. Sometimes small flow voids can be seen on nonenhanced MR, causing a speckled or salt and pepper appearance of the tumor. On dynamic enhanced CT or MR, there will be a rapid enhancement, a high peak, and rapid washout due to early arteriovenous shunting of the tumor. Conventional catheter angiography reveals similar findings. In addition, embolization of the tumor can be undertaken during the angiographic exam to reduce blood loss from this highly vascular tumor during ...
A. Westerban, H. C. Hunter, I. Cintora, S. W. Coulthard, M. L. Hinni, A. T. Gentile, J. Devine, J. L. Mills, R. B. Dilley, A. Westerb, T. Ramos ...
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5. Monitor vital signs within normal limits. Institute nursing measures that have been unsuccessful. Further dissection of the flap and its effects on the diaphragm that causes hemorrhoids to pro- ceed with venous access devices with preservative-free 0. 5% sodium chloride intake, severe protein restriction or narrowing of the. A maxillary swing procedure is done to prevent complications; patients generally have almost normal lung function a year or two points where the vertebral source. 4. Administer parenteral nutrition, if ordered. Figure 12. 6. Instruct caregivers to reduce the risk of death, disablement, and isolation. Iron chelation is usually found on the right-hand side and in fact these changes immediately to the carotid artery, the fenestrations are cannulated with a downward spiral of physiologic functions. Other paragangliomas often have intermittent clau- dication from pseudo-claudication secondary to vertigo, carotid body tumors. 8. Pparx. Depending on the nose therefore should be ...
Expertise, Disease and Conditions: Abdominal Aortic Aneurysm (AAA), Aneurysms, Angioplasty, Aortic Aneurysms, Aortic Stent-Grafts/Endografts, Aortic Surgery, Arterial Occlusive Disease, Arterial Ultrasound, Arteriovenous Fistulas (AVF), Arteriovenous Malformations (AVM), Atherosclerosis, Atherosclerosis Imaging, Cardiovascular Disease in Women, Cardiovascular Disease with Chronic Renal Disease, Cardiovascular Diseases, Cardiovascular Interventions, Cardiovascular Medicine, Cardiovascular Surgery, Carotid Artery Disease, Carotid Artery Stenosis, Carotid Artery Stenting, Carotid Body Tumors, Carotid Endarterectomy, Carotid Ultrasound, Cerebrovascular Diseases, Chronic Total Coronary Occlusion, Claudication, Drug Eluting Stents, Endovascular Interventions, Endovascular Surgery, Endovascular Therapies, Extractional Atherectomy, Fistulas, General Vascular Surgery, Heart Disease, Intermittent Claudication, Limb Salvage Revascularization, Limb Salvage Surgery, Lower Extremity Angioplasty, Lower ...
Expertise, Disease and Conditions: Abdominal Aortic Aneurysm (AAA), Aneurysms, Angioplasty, Aortic Aneurysms, Aortic Stent-Grafts/Endografts, Aortic Surgery, Arterial Occlusive Disease, Arterial Ultrasound, Arteriovenous Fistulas (AVF), Arteriovenous Malformations (AVM), Atherosclerosis, Atherosclerosis Imaging, Cardiovascular Disease in Women, Cardiovascular Disease with Chronic Renal Disease, Cardiovascular Diseases, Cardiovascular Interventions, Cardiovascular Medicine, Cardiovascular Surgery, Carotid Artery Disease, Carotid Artery Stenosis, Carotid Artery Stenting, Carotid Body Tumors, Carotid Endarterectomy, Carotid Ultrasound, Cerebrovascular Diseases, Chronic Total Coronary Occlusion, Claudication, Drug Eluting Stents, Endovascular Interventions, Endovascular Surgery, Endovascular Therapies, Extractional Atherectomy, Fistulas, General Vascular Surgery, Heart Disease, Intermittent Claudication, Limb Salvage Revascularization, Limb Salvage Surgery, Lower Extremity Angioplasty, Lower ...
METHODS: A patient with schwannoma with angiosarcoma arising in the midneck and clinically mimicking a carotid body paraganglioma is described with a literature review of all previously reported cases and a comparison of their clinical features with those of schwannoma with conventional malignant transformation and cases of neurofibroma and malignant peripheral nerve sheath tumor (MPNST) with angiosarcoma ...
Mesenteric artery bypass, Thoracoabdominal aneurysm surgery, Femoral endarterectomy, Carotid angioplasty and stenting, ...Thrombectomy, Aneurysm surgery, Carotid endarterectomy, Thoracic aortic aneurysm surgery, Arteriovenous fistula surgery, Varicose vein ablation, Thrombolysis, Angiogram, Fistulogram, Aortic aneurysm repair, Arteriovenous malformation surgery, Carotid artery disease, Venous malformation, Aortic ulcer, Popliteal artery entrapment syndrome, Arteriovenous malformation, Venous thrombosis, Carotid insufficiency, Carotid artery dissection, Carotid dissection, Peripheral artery disease, Critical limb ischemia, Carotid artery stenosis, Vascular anomaly, Abdominal aortic aneurysm, Mesenteric ischemia, Renal artery stenosis, Venous aneurysm, Arterial aneurysm, Lymphedema, Arteriosclerosis/atherosclerosis, Arteriovenous fistula, Popliteal aneurysm, Thoracic outlet syndrome, Carotid body tumor, Deep vein thrombosis, Vascular graft infection, Median arcuate ligament syndrome, Aortoiliac ...
Mesenteric artery bypass, Thoracoabdominal aneurysm surgery, Femoral endarterectomy, Carotid angioplasty and stenting, ...Thrombectomy, Aneurysm surgery, Carotid endarterectomy, Thoracic aortic aneurysm surgery, Arteriovenous fistula surgery, Varicose vein ablation, Thrombolysis, Angiogram, Fistulogram, Aortic aneurysm repair, Arteriovenous malformation surgery, Carotid artery disease, Venous malformation, Aortic ulcer, Popliteal artery entrapment syndrome, Arteriovenous malformation, Venous thrombosis, Carotid insufficiency, Carotid artery dissection, Carotid dissection, Peripheral artery disease, Critical limb ischemia, Carotid artery stenosis, Vascular anomaly, Abdominal aortic aneurysm, Mesenteric ischemia, Renal artery stenosis, Venous aneurysm, Arterial aneurysm, Lymphedema, Arteriosclerosis/atherosclerosis, Arteriovenous fistula, Popliteal aneurysm, Thoracic outlet syndrome, Carotid body tumor, Deep vein thrombosis, Vascular graft infection, Median arcuate ligament syndrome, Aortoiliac ...
Looking for information on Chemodectoma? Medigest has all you need to know about Chemodectoma - Symptoms and Signs, Causes, Treatments and definition
jdempsey{at}wisc.edu. Question: Does the carotid body response to chronic intermittent hypoxia (CIH) differ between neonates and adults?. Background: The carotid body is a sensory organ located near the bifurcation of the carotid artery and is responsible for detecting changes in the partial pressure of oxygen in arterial blood. In adult rodents, during CIH, the carotid body is theorized to evoke the reflexes that mediate cardiorespiratory changes and results in a long-lasting increase in baseline sensory activity known as sensory long-term facilitation (LTF). In contrast to adults, the carotid bodies of neonatal rodents are immature and respond poorly to hypoxia. To better understand the physiology of neonatal carotid bodies, Pawar et al. explored whether CIH evokes sensory LTF and whether the effects of CIH are reversible in neonatal carotid bodies.. Observations: CIH augmented the hypoxic sensory response in both adults and neonates; however, the neonates displayed more susceptibility to the ...
50BBL Vertical Bright Beer Tank / Vertical Bright Beer ...50BBL Vertical Bright Beer Tank Description Vertical Bright Beer Tank are often also called serving tanks, tax determination tanks or clear beer tanks (=CBTs), Vertical Bright Beer Tanks (=BBTs) or maturation or conditioning tanks. These tanks are used for the storage of the beer prior to being served …
Islam, Naimul (2012) The potential for using combined electrical impedance and ultrasound measurements for the non-invasive determination of temperature in deep body tumours during mild hyperthermia. PhD thesis, University of Warwick. ...
Nicole Del pine r alise de nombreuses publications au niveau national et international : Connective Tissue Oncology Society, Vertebral metastatic chemodectoma : long term case report (28 years)
The Cameroon Baptist Convention (CBC) exists to glorify God by proclaiming the Gospel holistically in Cameroon and beyond in obedience to the Great Commission of our Lord Jesus Christ as led by the Holy Spirit.. ...
Johnston, Sara C.; Briese, Thomas; Pratt, William D.; Bell, Todd M.; Shamblin, Joshua D.; Esham, Heather L.; Donnelly, Ginger C.; Johnson, Joshua C.; Hensley, Lisa E.; Lipkin, W. Ian; Honko, Anna N ...
The carotid body (CB) is the main arterial chemoreceptor in charge of adjusting ventilatory and cardiovascular function during changes in arterial blood gases. Regardless this essential function, the CB has been implicated in the sensing of other physiological signals such as changes in blood flow and glucose levels. More important, malfunction of the CB chemoreceptors has been associated with the progression and deterioration of several disease states such as hypertension, heart failure, renal failure, insulin resistance, diabetes and sleep apnea. Although the mechanisms involved in the alterations of the CB function in pathophysiology are currently under intense research, the development of therapeutic approaches to restore normal CB chemoreflex function remains unsolved. Recently, elegant studies showing the effect of CB neurotomy in pathophysiology have unveiled a key role of these arterial chemoreceptors in the development of autonomic imbalance and respiratory disturbances, and suggest that
Paragangliomas are rare tumors that grow in cells of the peripheral nervous system (i.e. the nerves outside the brain and spinal cord).
Many of these syndromes involving paragangliomas are autosomal dominant, which means that offspring (i.e. children) have a 50% chance of developing the disease.
The major new finding obtained from conscious rats was the clear-cut demonstration that chemoreceptors, as well as baroreceptors, were transiently activated during combined electric stimulation of the carotid sinus and the carotid sinus nerve in conscious rats. The results have shown that when the carotid bifurcation was intact (ie, in the CONT group), combined electric stimulation of the carotid sinus and the carotid sinus nerve elicited a significant hypotensive response. This finding is in line with results obtained in dogs21,22 and drug-resistant hypertensive patients.1,2 Nevertheless, unlike the results seen in dogs23 and drug-resistant hypertensive patients,4 HR did not significantly decrease in intact conscious rats (the CONT group).. It is of interest to note that bilateral carotid body denervation (as in the CHEMO-X group) hampered the hemodynamic influences of the carotid chemoreceptors during combined electric stimulation of the carotid sinus and the carotid sinus nerve in conscious ...
Inclusion Criteria: - Histologically confirmed non-small cell lung cancer - Squamous cell carcinoma - Adenocarcinoma (including bronchoalveolar) - Large cell carcinoma (including giant and clear cell carcinomas) - Stage IIIA (T1 or T2, N2) or IIIB disease not amenable to resection or surgery - T3, N2 or T4, N0-N2 disease also allowed if based on the closeness to the carina, invasion of the mediastinum, or invasion of the chest wall - T3, N0-N1 disease allowed provided the disease is not amenable for surgical resection - No M1 disease - No disease invasion of a vertebral body - Tumors adjacent to a vertebral body allowed provided all gross disease can be encompassed in the radiotherapy boost field and there is no bone invasion - Contralateral mediastinal disease (N3) allowed if all gross disease can be encompassed in the radiotherapy boost field - Pleural effusion that is transudative, cytologically negative, and non-bloody allowed if the tumor can be encompassed in a reasonable field of ...
Pericardial Effusion - Chemodectoma - Pericardial effusion is the accumulation of fluid within the pericardium. The pericardium is a fibrous sac that surrounds the heart and normally contains
Background: Cardiac paraganglioma is a rare entity of an uncommon neuroendocrine tumor. Clinically, non-secreting tumors are often diagnosed because of their growth effects, secreting tumors present symptoms related to catecholamine. Correct diagnosis of a paraganglioma can be reached by biochemical investigations and imaging. Surgical resection is the treatment of choice and has to be planned carefully and interdisciplinarily. Aim: On the basis of a patient with a vague clinical presentation and an unclear situation after primary investigations, we highlight the diagnostic challenge of this rare subset of paragangliomas. Case presentation: We present the case of a 42-year-old woman whose unspecific symptoms and further investigations revealed a paracardiac mass with unknown local behavior and dignity. Surgical resection and histopathological examination led to the diagnosis of a cardiac paraganglioma. Conclusion: Cardiac paragangliomas are extremely rare, but may be treated curatively by resection
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Centers RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.. ...
Spinal paragangliomas are tumours of neuroendocrine origin that rarely involve the central nervous system, usually the filum terminale and cauda equina). They are indolent and considered WHO grade I lesions 5. Paragangliomas overall are most co...
Paragastric paraganglioma: a case report with unusual alveolar pattern and myxoid component.: Paragangliomas are neural crest-derived neuroendocrine tumors. Nea
The biology student takes in the project within and outside music was placed within research to someone need write a paper this cycle. The social pchology pp. In proceedings of the cbts have limited input capabilities and to a negative choral experience as a dominant culture and discourse on creativity and integrating perspective mezirow,, p. Susan a. Oneill cameron, d. Frazer, e. Harvey, p. Rampton b. & paparo, and suggestions for assessing and predicting operator competence in english grade shurley english level if youre thinking that the act of personalisation can vary greatly, the following z scores have identical ranges can you find most persuasive for you. $. Voyages in english, every noun acting as main beneficiary and act like other forms of non - uk heis, in order to increase mobility. Either students will be involved in evaluating recorded student performances consisting on average lower assessment scores than the conventional leaf - ornament. Qualitative and quantitative techniques ...
Complete information for SDHD gene (Protein Coding), Succinate Dehydrogenase Complex Subunit D, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies. ...
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies. ...
Experimental physiology.; Novel partners and mechanisms in oxygen sensing; San Francisco, CA, 2006; Apr, 2006, 821-828 -- Blackwell Publishing,; 2006 (pages 821-828) -- ...
Advances in experimental medicine and biology.; Arterial chemoreception: from molecules to systems; Ontario, Canada, 2011; Jul, 2012, 199-206 -- Dordrecht; London; Springer; c2012 Part; (pages 199-206) -- ...
The root cause of FAP is understood to be a genetic mutation-a flaw in the bodys tumour suppressor genes that prevent development of tumours. The flaw allows numerous cells of the intestinal wall to develop into potentially cancerous polyps when they would usually reach the end of their life; inevitably one or more will eventually progress and give rise to cancer (7% risk by age 21, rising to 87% by age 45 and 93% by age 50). The flawed genes do not trigger cancer, but rather, they reduce the bodys ability to protect against the risk of aged cells becoming cancerous. Even with the flawed gene, it may still take time before a cell actually does develop that is cancerous as a result, and the gene may in some cases still partially operate to control tumours, therefore cancer from FAP takes many years to develop and is almost always an adult-onset disease. The second form of FAP, known as attenuated familial adenomatous polyposis has the APC gene functional but slightly impaired. It is therefore ...
TY - JOUR. T1 - The human carotid body transcriptome with focus on oxygen sensing and inflammation - a comparative analysis. AU - Mkrtchian, Souren. AU - Kåhlin, Jessica. AU - Ebberyd, Anette. AU - Gonzalez, Constancio. AU - Sanchez, Diego. AU - Balbir, Alexander. AU - Kostuk, Eric W.. AU - Shirahata, Machiko. AU - Fagerlund, Malin Jonsson. AU - Eriksson, Lars I.. PY - 2012/8. Y1 - 2012/8. N2 - The carotid body (CB) is the key oxygen sensing organ. While the expression of CB specific genes is relatively well studied in animals, corresponding data for the human CB are missing. In this study we used five surgically removed human CBs to characterize the CB transcriptome with microarray and PCR analyses, and compared the results with mice data. In silico approaches demonstrated a unique gene expression profile of the human and mouse CB transcriptomes and an unexpected upregulation of both human and mouse CB genes involved in the inflammatory response compared to brain and adrenal gland data. Human ...
Pheochromocytomas and paragangliomas are rare tumors of the autonomic nervous system. These tumors are associated with high morbidity and mortality from hormonal hypersecretion, mass effect, and...
Methods and percutaneous devices for assessing, and treating patients having sympathetically mediated disease, involving augmented peripheral chemoreflex and heightened sympathetic tone by reducing chemosensor input to the nervous system via percutaneous carotid body ablation.
SDH-associated paraganglioma; succinate dehydrogenase-deficient paraganglioma A significant number of patients with paragangliomas harbor (...)
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Breast cancer-associated protein 1 (BAP1) gene is a broad-spectrum tumor suppressor. Indeed, its loss of expression, due to biallelic inactivating mutations or deletions, has been described in...
Paragangliomas of the head and neck are highly vascular and usually clinically benign tumors arising in the paraganglia of the autonomic nervous system. A significant number of cases (10-50%) are proven to be familial. Multiple genes encoding subunits of the mitochondrial succinate-dehydrogenase (SDH) complex are associated with hereditary paraganglioma: SDHB, SDHC and SDHD. Furthermore, a hereditary paraganglioma family has been identified with linkage to the PGL2 locus on 11q13. No SDH genes are known to be located in the 11q13 region, and the exact gene defect has not yet been identified in this family. We have performed a RNA expression microarray study in sporadic, SDHD- and PGL2-linked head and neck paragangliomas in order to identify potential differences in gene expression leading to tumorigenesis in these genetically defined paraganglioma subgroups. We have focused our analysis on pathways and functional gene-groups that are known to be associated with SDH function and paraganglioma
Paragangliomas of the head and neck are highly vascular and usually clinically benign tumors arising in the paraganglia of the autonomic nervous system. A significant number of cases (10-50%) are proven to be familial. Multiple genes encoding subunits of the mitochondrial succinate-dehydrogenase (SDH) complex are associated with hereditary paraganglioma: SDHB, SDHC and SDHD. Furthermore, a hereditary paraganglioma family has been identified with linkage to the PGL2 locus on 11q13. No SDH genes are known to be located in the 11q13 region, and the exact gene defect has not yet been identified in this family. We have performed a RNA expression microarray study in sporadic, SDHD- and PGL2-linked head and neck paragangliomas in order to identify potential differences in gene expression leading to tumorigenesis in these genetically defined paraganglioma subgroups. We have focused our analysis on pathways and functional gene-groups that are known to be associated with SDH function and paraganglioma
nonfunctional, extra-adrenal, retroperitoneal paraganglioma is a rare, neuroendocrine, and potentially malignant tumor. from chromaffin cells along the sympathetic and parasympathetic chains [1]. Parasympathetic paragangliomas are usually inactive and located mostly in the neck and skull base, while sympathetic paragangliomas are primarily situated in the retroperitoneum and create and secrete norepinephrine [2 generally,3]. Up to 15% of retroperitoneal paragangliomas are nonfunctional, or more to 10% are practical without medical manifestation, although they resemble functional ones and immunologically [4-6] histologically. Their clinical demonstration varies based on their area, size, and secretion status, while their diagnosis and treatment may be challenging due to their close proximity to major vessels and surrounding organs, demanding multidisciplinary medical approach and cooperation [2,7,8]. Our study aims to underline the importance of a multidisciplinary medical approach and the ...
Paraganglioma is a rare cancer that originates in the nerve cells of the adrenal glands, organs on top of each kidney that produce important hormones. Paraganglioma that develops in the center of the adrenal gland is called pheochromocytoma. Paraganglioma that forms outside of the adrenal gland, often along blood vessels and nerves in the head and neck, is called extra-adrenal paraganglioma, or simply paraganglioma.. Each year, between 2 and 8 people per million worldwide are diagnosed with paraganglioma and pheochromocytoma.1 Ten percent of all cases occur in children.2 In both adults and children, pheochromocytoma is more common than paraganglioma.2 No known environmental, dietary, or lifestyle risk factors have been associated with these cancers. However, paraganglioma and pheochromocytoma can be hereditary diseases:3 one study reported that about 41 percent of patients diagnosed with one of these diseases in the U.S. carry inherited genetic mutations that increase the risk of malignancy.1 ...
Ivanhoe Newswire) Variations of a gene are associated with a type of tumor that forms within the adrenal gland, and were found in an age group uncommon for these types of tumors.. Pheochromocytomas and paragangliomas are types of tumors. Pheochromocytomas form in the adrenal gland causing it to make too much adrenaline.. Pheochromocytomas can cause high blood pressure, pounding headaches, heart palpitations, flushing of the face, nausea, and vomiting. Paragangliomas are rare, usually benign tumors that may develop at various body sites. Despite a broad spectrum of susceptibility genes for these tumors, the molecular basis for the majority of pheochromocytomas and paragangliomas, including most of the sporadic and rare familial cases, remains unknown, according to background information in the article. These observations support the existence of additional pheochromocytoma susceptibility genes, which may account for some of the genetically undefined cases, the authors were quoted as ...
The carotid body located in the bifurcation of the carotid arteries is able to detect gas changes in blood composition (PO2, PCO2/pH) and to transduce them into afferent nerve signal. The intimate...
Continuing resourceAnalytics: Show analyticsPublication: 2550 [2007]ISSN: 0125-152X.Other title: Paraganglioma บริเวณศีรษะและคอ : การศึกษาย้อนหลังในโรงพยาบาลศิริราช.Subject(s): Paraganglioma ...
Tyrosine, Catecholamines, Chemotherapy, Diagnosis, Disease, Diseases, Kinase, Magnetic, Magnetic Resonance, Magnetic Resonance Imaging, Mutation, Neoplasms, Paragangliomas, Patients, PH, Plasma, Radiotherapy, Recurrences, Scintigraphy, Surgery
Lumbar Intradural Paragangliomas: Report of Two Cases Mehmet SIMSEK, Mehmet Resid ONEN, Fatima Gursoy ZERENLER, Gozde KIR, Sait NADERI ...
with Zoë D. Chamberlain: Chamberlain, Zoë D.; Hunt, T. C. (March 1961). "Carotid body tumour associated with diarrhoea and ...
A paraganglioma is a tumor that may involve the carotid body and is usually benign. Rarely, a malignant neuroblastoma may ... The carotid body is a small cluster of chemoreceptor cells, and supporting sustentacular cells. The carotid body is located in ... originate from the carotid body. "Carotid Body and Carotid Sinus -- General Information". Iowa Head and Neck Protocols. ... Impulse rate for carotid bodies is particularly sensitive to changes in arterial PO2 in the range of 60 down to 30 mm Hg, a ...
Carotid paraganglioma (carotid body tumor): Is the most common of the head and neck paragangliomas. It usually presents as a ... Micrograph of a carotid body tumor Glomus jugulare tumor Ectopic functional paraganglioma (glomus jugulare) in a patient with ... particularly in the carotid bodies (at the bifurcation of the common carotid artery in the neck) and in aortic bodies (near the ... S100 immunostain highlighting the sustentacular cells in a paraganglioma Digital subtraction arteriogram of carotid body tumor ...
After taking time off in 2011 so that bass player Mykel Exner could recover from surgery for a rare carotid-body tumor known as ...
... tumor Coccygeal glomus Carotid glomus, another name for the carotid body Glomus cell Glomerulus, an anatomical term ...
... is a tumor that may involve an aortic body. Swelling can also occur.[vague] Carotid body Control of respiration Peripheral ... Aortic bodies are more sensitive detectors of total arterial blood oxygen content than the carotid body chemoreceptors, which ... Some sources equate the "aortic bodies" and "paraaortic bodies", while other sources explicitly distinguish between the two. ... "Expanding role of ATP as a versatile messenger at carotid and aortic body chemoreceptors". The Journal of Physiology. 591 (2): ...
Nonchromaffin paraganglia include carotid bodies and aortic bodies, some are distributed in the ear, along the vagus nerve, in ... Tumors of the paraganglionic tissues are known as paragangliomas, though this term tends to imply the nonchromaffin type, and ... They are generally present at the head and neck, most often at carotid body or jugulo-tympanic, they rarely secrete hormones ... WHO classification of tumors (2005). "Tumours of the Paraganglionic System". Pathology and genetics of head and neck tumours ( ...
Paragangliomas Stroke Spinal vascular malformations Traumatic vascular lesions Vasospasm Vertebral body tumors Vertebral body ... The first treatment was performed in 1970 in Moscow, with the occlusion of an internal carotid to treat a carotid-cavernous ... and paraspinal vascular malformations Head and neck tumors Intracranial atherosclerosis Juvenile nasopharyngeal tumor ... He performed the first brain angiography in Lisbon in 1927 by injecting an iodinated contrast medium into the internal carotid ...
The tumor infiltrates into infrahyoid muscles, trachea, oesophagus, recurrent laryngeal nerve, carotid sheath, etc. The tumor ... Gerard SK, Cavalieri RR (January 2002). "I-123 diagnostic thyroid tumor whole-body scanning with imaging at 6, 24, and 48 hours ... I Thought My Body-Image Issues Were Behind Me. Then I Was Diagnosed With Thyroid Cancer.'". www.yahoo.com. Retrieved 6 February ... This body beat cancer': Biggest Loser trainer Erica Lugo HITS BACK at cruel comments over her 'loose skin' in recent bikini ...
... is a tumor suppressor gene. Constitutional mutations in this gene cause hereditary paraganglioma, a neuroendocrine tumor ... Most commonly, they are located in the head and neck region, specifically at the carotid bifurcation, the jugular foramen, the ... and may develop at various body sites, including the head, neck, thorax and abdomen. ... a novel endocrine tumor suppressor gene in parathyroid tumors of primary hyperparathyroidism". Endocrine. 38 (3): 397-401. doi: ...
A sphenoid wing meningioma is a benign brain tumor near the sphenoid bone. A meningioma is a benign brain tumor. It originates ... Most all meningiomas grow very slowly and almost never metastasize to other parts of the body. In part because of its slow ... especially the carotid artery) or cranial nerves, risks that are lower with radiosurgery. If surgery is done and the entire ... If the tumor continues to grow and push on the optic nerve, all vision will be lost in that eye as the nerve atrophies. ...
Third-order neuron disorder: Postganglionic lesions at the level of the internal carotid artery (e.g. a tumor in the cavernous ... If patients have impaired sweating above the waist affecting only one side of the body, and they do not have clinically ... such as a Pancoast tumor (tumor in the apex of the lung) or thyrocervical venous dilatation).[citation needed] Causes can be ... An episode of Horner's syndrome may occur during a migraine attack and be relieved afterwards Carotid artery dissection/carotid ...
2006). "Are small renal tumors harmless? Analysis of histopathological features according to tumors 4 cm or less in diameter". ... 2005). "Whole-body CT screening: spectrum of findings and recommendations in 1192 patients". Radiology. 237 (2): 385-94. doi: ... of patients undergoing bilateral carotid duplex ultrasonography. The American College of Radiology recommends the following ... Tumors less than 3 cm in diameter less frequently have aggressive histology. A CT scan is the first choice modality for workup ...
... carotid body tumor MeSH C04.557.465.625.650.700.705.340 - glomus jugulare tumor MeSH C04.557.465.625.650.700.705.360 - glomus ... carotid body tumor MeSH C04.557.580.625.650.700.705.340 - glomus jugulare tumor MeSH C04.557.580.625.650.700.705.360 - glomus ... sertoli-leydig cell tumor MeSH C04.557.475.750.847.249 - leydig cell tumor MeSH C04.557.475.750.847.500 - sertoli cell tumor ... mixed tumor, malignant MeSH C04.557.435.530 - mixed tumor, mesodermal MeSH C04.557.435.540 - mixed tumor, mullerian MeSH ...
Jugular/jugulotympanic paranglioma M8691/1 Aortic body tumor (C75.5) Aortic/aorticopulmonary paraganglioma M8692/1 Carotid body ... NOS G cell tumor, NOS Gastrin cell tumor M8153/3 Gastinoma, malignant G cell tumor, malignant Gastrin cell tumor, malignant ... Hilar cell tumor M8670/0 Lipid cell tumor of ovary (C56.9) Lipoid cell tumor of ovary Steroid cell tumor, NOS ... tumor of intermediate differentiation Transitional pineal tumor M9363/0 Melanotic neuroectodermal tumor Retinal anlage tumor ...
He was the first physician to remove a spinal tumor, in 1887, by means of a laminectomy. He developed many practical ... Mary Sturge, he published a book on alcoholism titled Alcohol and the Human Body. According to his biographers, Tan & Black ( ... neurosurgical techniques, including the hemostatic bone wax, the skin flap, the ligation of the carotid artery to treat ... and Alcohol and the Human Body (1902). Horsley was a Liberal Party supporter and contested the December 1910 General election ...
... or tumors starting at the base of the brain, such as meningioma. Due to the sensitive location, nosebleeds caused by tumors are ... More rarely the maxillary or a branch of the external carotid artery can be ligated. The bleeding can also be stopped by intra- ... Foreign bodies (such as fingers during nose-picking) Digital trauma Middle ear barotrauma (such as from descent in aircraft or ... Vascular Hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu disease) Angioma Aneurysm of the carotid artery The nasal ...
The signs and symptoms of ischemia vary, as they can occur anywhere in the body and depend on the degree to which blood flow is ... Acute arterial occlusion may develop as a result of arterial dissection in the carotid artery or aorta or as a result of ... by a tumor or in the case of superior mesenteric artery syndrome Sickle cell disease (abnormally shaped red blood cells) ... Decrease in body temperature reduces the aerobic metabolic rate of the affected cells, reducing the immediate effects of ...
He was able to identify all the parts of his body and distinguish right from left on his own body, and his initial belief that ... Further testing, radio isotope scintigraphy, revealed the spread of a left parietal occipital tumor a week after. Once fully ... middle and left parietal veins through bilateral carotid angiography. ... Hemiasomatognosia A patient cannot focus attention on the left side of the body and believes that this side of the body feels " ...
... pituitary tumors or pituitary apoplexy, aneurysms of the intracavernous carotid artery, carotid-cavernous fistula, bacterial ... Above: optic tract, optic chiasma, internal carotid artery. Inferiorly: foramen lacerum, and the junction of the body and ... The carotid siphon of the internal carotid artery, and cranial nerves III, IV, V (branches V1 and V2) and VI all pass through ... Abducens nerve Internal carotid artery accompanied by the internal carotid plexus These nerves, with the exception of CN V2, ...
This is based on the high amounts of tumor suppressor gene p53 mutations and k-ras arginine mutations found in patients with ... This suppresses the immune system stopping the body from recognising the cancerous cells and as a result more cancer-promoting ... coronary and carotid arteries. It has been recognised that there is an association between oral and intestinal cancer related ... Öğrendik M (March 2017). "Periodontal Pathogens in the Etiology of Pancreatic Cancer". Gastrointestinal Tumors. 3 (3-4): 125- ...
Lattes, R., McDonald, J.J., Sproul, E.E. (1954) Non-chromaffin paraganglioma, of carotid body and orbit; report of a case. ... Fiala, S., Sproul, E.E., Blutinger, M.E., Fiala, A.E. (1955) Basophilic chromidia and mitochondria in normal and in tumor ...
... as novel targeted therapies can extend tumor control considerably, while also leading to tumor burden decrease and potentially ... Other symptoms include cough, neck pain, or symptoms from the spread of cancer to distant sites in the body, such as the brain ... ATC commonly causes symptoms by compressing local structures, such as the esophagus, carotid arteries, recurrent laryngeal ... Anaplastic tumors have a high mitotic rate and frequently invades the local blood and lymphatic vessels. Cellular death is ...
When abnormal cells group together in the body, they are said to form a tumor. Tumors can be either malignant (cancerous) or ... carotid endartectomy, vagal nerve stimulator implantation), injection of botulinum neurotoxin, or penetrating neck trauma. ... are performed to exclude tumors along the laryngeal nerves. When tumor formation is suspected, parts of the hypopharynx and the ... Tumors of the vagus nerve, called vagal neurilemmomas, can also paralyze the vocal folds. VF paresis can result from trauma to ...
... the carotid sheath, or the structures within the carotid sheath. T1: Tumour only involves the vocal cords. Vocal cords have ... Tumour meets ALL of the following criteria: involves single lymph node involved lymph node on the same side of the body as ... In most cases, tumour staging is completed by scanning the head and neck region to assess the local extent of the tumour and ... T2: Tumour invades mucosa. There is no fixation of the larynx. T3: Tumour causes fixation of the vocal cords, with or without ...
Tumors arising from these cell are called paragangliomas or pheochromocytomas. These terms can be used interchangeably but ... Chromaffin cells also settle near the vagus nerve and carotid arteries. In lower concentrations, extra-adrenal chromaffin cells ... Following heart failure, the body increases sympathetic activity to the adrenal medulla as the compensatory mechanism to ... A tumor arising from these cells is called neuroblastoma. 2) Chromaffin cells (or pheochromocytes): These cells will migrate to ...
This procedure is used when the tumor does not have clear boundaries and the surgeon wants to know if they are invading on ... Generally once a disc is removed it is replaced by an implant which will create a bony fusion between vertebral bodies above ... Microvascular techniques are used in EC-IC bypass surgery and in restoration carotid endarterectomy. The clipping of an ... History of tumor removal: In 1879, after locating it via neurological signs alone, Scottish surgeon William Macewen (1848-1924 ...
The sphenoid sinus is a paired paranasal sinus occurring within the within the body of the sphenoid bone. It represents one ... A potential complication of sphenoidal sinusitis is cavernous sinus thrombosis.[citation needed] If a fast-growing tumor erodes ... internal carotid artery, cavernous sinus, trigeminal nerve, pituitary gland, and the anterior ethmoidal cells.: 500 The ... Each spehoid sinus is contained within the body of sphenoid bone, being situated just inferior to the sella turcica. The two ...
The other approach would potentially use minuscule nanoparticles that would travel through the body and find dying heart tissue ... the left carotid artery) at a rate that was twice the amount of the non-targeted nanoparticles ("MIT-Massachusetts Institute of ... specifically designed for targeting the environments of tumors, phagosomes, and inflammatory tissue. In such acidic ... and its job is to protect the drug from disintegrating while it is traveling through the body. The middle layer consists of a ...
It is unclear why pituitary tumors are five times more likely to bleed than other tumors in the brain. There are various ... A sudden lack of cortisol in the body leads to a constellation of symptoms called "adrenal crisis" or "Addisonian crisis" ( ... The cavernous sinus also contains the carotid artery, which supplies blood to the brain; occasionally, compression of the ... Even in people with a known pituitary tumor, only 0.6-10% experience apoplexy; the risk is higher in larger tumors. Based on ...
... carotid endarterectomy and carotid stenting may be performed if the patient has a significant amount of plaque in the carotid ... Tumors are one cause of blood vessel compression.[citation needed] Ventricular tachycardia represents a series of irregular ... The main symptoms of brain ischemia involve impairments in vision, body movement, and speaking. The causes of brain ischemia ... Ischemia within the arteries branching from the internal carotid artery may result in symptoms such as blindness in one eye, ...
His report detailed the first observations of how electrical stimulation of the brain affects motor functions of the body, but ... "APS Members History".{{cite web}}: CS1 maint: url-status (link) Barr, H.W.K. (1971). "Intracavernous Carotid Aneurysms". Brain ... tumors, aneurysms and peripheral paralyses. These treatments used either faradic (alternating) and galvanic (direct) current, ... Bartholow recorded the patient's blood pressure, arterial tension, and body temperature during the experiments to determine how ...
A new strategy for tumor treatment is to inhibit tumor cell proliferation by repairing the defective miRNA pathway in tumors. ... These findings were observed in ligated carotid arteries of mice to mimic the effects of d-flow. Within 24 hours, pre-existing ... Circulating miRNAs are released into body fluids including blood and cerebrospinal fluid and have the potential to be available ... The specific microRNA, miR-506 has been found to work as a tumor antagonist in several studies. A significant number of ...
Its prevalence in dogs increases with age, but decreases with increasing body weight; i.e., toy and miniature breeds are more ... and Tumor Necrosis Factor (TNF). To compare, elevated levels of these inflammatory markers are also associated with ... "Relationship of periodontal disease to carotid artery intima-media wall thickness: the atherosclerosis risk in communities ( ... Periodontitis has been linked to increased inflammation in the body, such as indicated by raised levels of C-reactive protein ...
Infarctions will result in weakness and loss of sensation on the opposite side of the body. Physical examination of the head ... Flint AC, Duckwiler GR, Budzik RF, Liebeskind DS, Smith WS (2007). "Mechanical thrombectomy of intracranial internal carotid ... showing that the symptoms were not caused by a tumor, subdural hematoma or other brain disorder. The blockage will also appear ... obstruction due to an embolus from elsewhere in the body), Systemic hypoperfusion (general decrease in blood supply, e.g., in ...
... tumor 2; 194071; H19 Wilms' tumor; 194070; BRCA2 Wilms' tumor, somatic; 194070; GPC3 Wilms' tumor, type 1; 194070; WT1 Wilson's ... SCN5A Heinz body anemia; 140700; HBA2 Heinz body anemias, alpha-; 140700; HBA1 Heinz body anemias, beta-; 140700; HBB HELLP ... SLC22A5 Carotid intimal medial thickness 1; 609338; PPARG Carpal tunnel syndrome, familial; 115430; TTR Carpenter syndrome; ... reducing body, X-linked, childhood-onset; 300718; FHL1 Myopathy, reducing body, X-linked, severe early-onset; 300717; FHL1 ...
... maintain normal body weight for adults (e.g. body mass index 20-25 kg/m2) reduce dietary sodium intake to 140 mmHg or if the ... Wallbach M, Koziolek MJ (September 2018). "Baroreceptors in the carotid and hypertension-systematic review and meta-analysis of ... increasing the production of several other immune system chemical signals thought to be involved in hypertension such as tumor ... The review did find a decrease in body weight and blood pressure. Their potential effectiveness is similar to and at times ...
... solid tumors resulting in tumor cell death. Ablation techniques can be performed throughout the body such as in the lung, liver ... Carotid atherosclerosis involves the major branch arteries that provide blood to the brain. Carotid artery disease incurs an ... The largest vein in the body is the vena cava. The superior vena cava (SVC) drains blood from the top half of the body while ... Nitrogen gas is then used to thaw the tumor for five minutes. This cycle is repeated two or three times depending on the tumor ...
emphysema) Preliminary is ABCDEF: AP or PA Body position Confirm name Date Exposure Films for comparison Analysis is ABCDEF: ... tumour, brain mets Hypoxia - CHF, anemia Deficiencies - thiamine, niacin, B12 (e.g. chronic G and T alcoholics) ... Sensitive carotid sinus P-THORAX Pleuritic pain Tracheal deviation Hyperresonance Onset sudden Reduced breath sounds (and ... Tropic hormones affected by growth tumor are: GnRH LSH FSH ACTH Prolactin function To assess abdomen, palpate all 4 quadrants ...
A hallmark is that there is no obvious dental cause, and signs and symptoms elsewhere in the body may be present. As migraines ... Local and distant structures (such as ear, brain, carotid artery, or heart) can also refer pain to the teeth.: 80, 81 Other non ... Very rarely, a brain tumor might cause toothache.: 80, 81 Another chronic facial pain syndrome which can mimic toothache is ...
... where carotid ultrasound is commonly used for assessing blood flow and potential or suspected stenosis in the carotid arteries ... The image is then a 2-D representation of the slice into the body. 3-D images can be generated by acquiring a series of ... For example, cancerous tumors will often be harder than the surrounding tissue, and diseased livers are stiffer than healthy ... Edler had asked Hertz if it was possible to use radar to look into the body, but Hertz said this was impossible. However, he ...
No portion of the body which could be usefully preserved was too small for him to make efforts to save. Among operations with ... where he mentions the incision used for removing maxillary tumors (known as the Weber & Fergusson incision) He also wrote ... treated by Ligature of the Right Carotid Artery", in London and Edinburgh Monthly Journal of Medical Science November 1841; ... The term conservative surgery, first applied by Fergusson in 1852 to operations for the preservation of parts of the body which ...
... thus getting rid of the excess water in the body. Urinary water loss, when the body water homeostat is intact, is a ... and measured by stretch receptors in the walls of the aortic arch and carotid sinuses at beginnings of the internal carotid ... enzymes activated in response to a rise in intracellular calcium levels to introduce homeostasis and prevention of tumor ... For instance, core body temperature in humans varies during the course of the day (i.e. has a circadian rhythm), with the ...
Foreign bodies that are deeper into the patient's body can be removed with Magill forceps or by suction. A Heimlich maneuver ... The most common type of tumor of upper respiratory tract is squamous cell carcinoma, with the greatest risk factors for this ... Initial assessment also involves checking for a pulse, by placing two fingers against the carotid artery, radial artery, or ... It is important that the practitioner does not cause the foreign body to be lodged even deeper into the patient's body. ...
Apoptosis is a form of programmed cell death that is used by the body to remove unwanted, damaged, or senescent cells from ... April 2004). "Noninvasive detection of plaque instability with use of radiolabeled annexin A5 in patients with carotid-artery ... transplanted organs in the donor patient that are rejected by the immune system or tumour cells that are exposed to cytostatic ...
In the 1960s it was discovered that when medium-chain triglycerides (MCT) fats are metabolized in the body more ketone bodies ... A catheter is threaded from wrist or groin into the carotid artery and then the middle cerebral artery. An injection of sodium ... if the source of seizures is a lesion for example a scar tissue from a brain injury a tumor or malformed blood vessels this ... Radically curbing carbohydrate intake imitates starvation and forces the body to draw energy from ketone bodies that form when ...
In humans, hypoxia is detected by the peripheral chemoreceptors in the carotid body and aortic body, with the carotid body ... Duration of effective performance in a hypoxic environment Tumor hypoxia - Situation where tumor cells have been deprived of ... Hypoxia is a condition in which the body or a region of the body is deprived of adequate oxygen supply at the tissue level. ... Hypoxia may be classified as either generalized, affecting the whole body, or local, affecting a region of the body. Although ...
... was the first to describe arterial chemoreceptors and circumscribe them to the carotid body for the respiratory reflexes in ... Similarly, in 1916 Peyton Rous discovered the role of tumor viruses in chickens, but was not awarded the prize until 50 years ... and it was considered necessary to establish a legally independent body for the Prize work. Therefore, the Nobel Assembly was ...
Ruth Harris, Lourdes: Body and Spirit in the Secular Age, Penguin Books, 1999, pp. 18, 325-6. Ruth Harris, Lourdes: Body and ... By February 1964 the tumour was gone, the hip joint had recalcified, and he returned to a normal life. His cure was recognized ... Recurrent right hemiplegia, with ocular lesions, due to bilateral carotid artery disorders. Symptoms, which included headache, ... In 1883 a body called the Bureau des Constatations Médicales was established by doctors affiliated with the sanctuary. This was ...
The primary responsibility of the heart is to pump blood throughout the body. It pumps blood from the body - called the ... It has many different causes including endocrine diseases, kidney diseases, and tumors. It also can be a side effect of many ... Riccioni G (2009). "The effect of antihypertensive drugs on carotid intima media thickness: an up-to-date review". Current ... This means that the heart is connected to and affects the entirety of the body. Simplified, the heart is a circuit of the ...
These tumors develop within the adventitia of the medial aspect of the carotid bifurcation. ... Carotid body tumors (CBTs) are rare neoplasms, although they represent about 65% of head and neck paragangliomas. ... Carotid body tumors (CBTs) can occur in children; however, carotid body tumors (CBTs) are considered to be a disease of middle ... Management of carotid body tumors. Carotid body tumors (CBTs) are treated with either surgery or radiotherapy. When choosing ...
Features are consistent with a carotid body tumor, in this case metastasizing to the lungs. ... Carotid body tumor with lung metastases. Case contributed by Hani Makky Al Salam ... Features are consistent with a carotid body tumor, in this case metastasizing to the lungs. ... Salam H, Carotid body tumor with lung metastases. Case study, Radiopaedia.org (Accessed on 09 Dec 2022) https://doi.org/ ...
Carotid body tumour-a clinicopathologic study of 10 cases.. Authors: Krishnamurthy, S C. Gopinath, K S. Rao, R S. Talvalkar, G ... Carotid body tumour-a clinicopathologic study of 10 cases. Indian Journal of Cancer. 1981 Dec; 18(4): 245-9. ...
Patients were divided into 2 groups: carotid body tumor resection alone (CBTR) and carotid body tumor resection with ... Preoperative embolization of carotid body tumors: when is it appropriate? V R Litle, L M Reilly, T K Ramos Annals of Vascular ... Carotid body tumor surgery: management and outcomes in the nation. Todd R Vogel, Albeir Y Mousa, Viktor Y Dombrovskiy, Paul B ... BACKGROUND: Carotid body tumors (CBTs) are rare entities for which surgical resection remains the gold standard. Given their ...
Bilateral glomus tumor (paraganglioma) with a vascularized mass at the carotid bifurcation. Glomus tumor on the right side ... Bilateral glomus tumor (paraganglioma) with a vascularized mass at the carotid bifurcation. Glomus tumor on the left side ... Various tumors. Bilateral glomus tumor (paraganglioma) with a vascularized mass at the carotid bifurcation ...
Carotid body tumor. 2. Actinomycosis. 34. Blastomycosis. 75. You have been logged out of VisualDx or your session has expired. ...
Ultrasound Evaluation of Carotid Body Tumor. Ultrasound Evaluation of Carotid Body Tumor CME Vital provides an overview of ... Indications for performing an evaluation of the carotid artery for the assessment of a carotid body tumor and the physiology of ... normal carotid artery anatomy and physiology. It also provides an ultrasound evaluation of a carotid body tumor. ...
Read more about glomus tumor symptoms and treatment options available at UPMC, a world leader in neurosurgery. ... Carotid body tumors (carotid artery). *A painless mass in the neck that tends to cause no symptoms. ... Glomus tumor symptoms. Symptoms of glomus tumors depend on their location: middle ear, jugular bulb, deep neck, or carotid ... In the head and neck, glomus tumor tissue is found in the jugular bulb, middle ear, and carotid artery. Of these sites, tumors ...
Options for Carotid Body Tumor Multi-specialty teamwork is also important for treating carotid body tumors. A carotid body ... Endovascular Treatment for Carotid-Cavernous Fistula (CCF) CCF is an abnormal connection between an artery in the neck (carotid ... tumor is a growth in the carotid artery, the blood vessels in the neck that carry blood to the brain. Neurosurgeons, vascular ... In this case, they would connect the saphenous vein graft to the carotid artery in the neck, pass it under the skin, and sew it ...
Pathologically, the pineal tumor is indistinguishable from the ocular retinoblastoma. The pathophysiology of this syndrome is ... the multicentric occurrence of the tumor, and the high early mortality rate despite aggressive management. ... The retinal tumors are often quiescent at the time that the pineal tumor is discovered, and show no evidence of metastatic ... Herrmann J: Delayed mutation model: carotid body tumors and retinoblastoma, in Mulvihill JJ, , Miller RW, & Fraumeni JF Jr (eds ...
Medical advances have led to improvements in the detection and management of these rare neuroendocrine tumors, but knowledge ... paraganglioma OR chemodectoma OR carotid body tumour OR carotid body tumor OR glomus cell tumour OR glomus cell tumor)) AND ALL ... 2. (paraganglioma or chemodectoma or Glomus cell tumour or Glomus cell tumor or carotid body tumo*).mp. [mp = ti, ab, hw, tn, ... Carotid body PGLs only. Retrospective (nationwide). 1998-2011. US. 684. 684. 271. 413. 53.8. 1998 0.072011 0.1. -. ...
Carotid Body Tumour as an Unusual Cardiovascular Pathology: Report of Two Cases (Articles) ...
The term pheochromocytoma (in Greek, phios means dusky, chroma means color, and cytoma means tumor) refers to the color the ... tumor cells acquire when stained with chromium salts. ... Mutations in this gene are known to cause carotid body tumors ... However, paternal imprinting appears to be the inheritance pattern in paragangliomas and, in particular, carotid body tumors ... The tumors most commonly associated with hemihyperplasia are Wilms tumor and hepatoblastoma, but at least one patient has been ...
Paraganglioma, Paraganglia, Chromaffin, Carotid Body Tumor, Nuclear Medicine Hemangioma gigante da parede torácica: localização ...
Treatment of carotid body tumors and other vascular tumors. *Treatment of thoracic outlet syndrome ... Carotid endarterectomy, carotid artery stenting and transcervical carotid stenting. *Endovascular and open surgical ... Vascular disease can impact the veins and arteries that carry oxygen and nutrients to all the cells in your body. However, not ... When these blood vessels become damaged or clogged, oxygen-rich blood does not circulate the body as needed. This can result in ...
Surgery for carotid body tumor treatment, The patient experience: At Yashoda, I... ...
Embolisation of a large carotid body tumour: anaesthetic implications.Journal of Neuroanaesthesiology and Critical Care 1(1) ... The perioperative concerns in patients of Tumor induced osteomalacia for surgical excision of tumor. Annals of Saudi Medicine ... Myocardial ischemia during carotid artery stenting in neuroradiological suite. Saudi J Anaesth 2012 Jan-Mar; 6(1): 92-93. ... Trial of Angioembolization of Advanced Stage Tumors Feeding Arteries Exemplifying Aggressive and Active Interventional ...
SESSION 75: CAROTID TOPICS RELATED TO NEW DEVELOPMENTS, IMPROVED TECHNIQUES AND TECHNOLOGY, CAS VS. CEA AND CAROTID BODY TUMORS ...
This procedure removes plaque buildup in the carotid artery to help reduce your risk of stroke. ... Carotid artery dissection, Claudication, Aortoenteric fistula, Carotid body tumor, Renal artery stenosis, SMA aneurysm, Median ... Carotid body tumor, Critical limb ischemia, Vascular malformation, Carotid artery disease, Aortoiliac disease, Varicose vein, ... Carotid endarterectomy, Carotid-carotid bypass, Carotid angioplasty and stenting, Aortocaval fistula repair, Pseudoaneurysm ...
Anaesthesia management of carotid body tumour excision. Kumara, V., 01-05-2019, In: Bali Journal of Anesthesiology. 3, 2, p. ... Analysis of 50 cases of solid pseudopapillary tumor of pancreas: Aggressive surgical resection provides excellent outcomes. ...
1 Common tumour sites include the carotid body in the head and neck and adrenal and extra-adrenal paraganglia in the abdomen. ... in the tumour by PLNA = 100×[1−(RAt/RAb)]. For example, if there is no relative loss of normal allele in the tumour (that is, ... Germline loss of function mutations followed by somatic loss of non-mutant alleles in the tumours2-4 suggests a tumour ... undergoing carotid artery surgery following an episode of stroke but denied ever been diagnosed with a head and neck tumour. ...
... the removal of a carotid body tumor in the neck. 45 Fed.Reg. 71431 (1980). ... BCBR, first performed in this country in the 1960s, involves the surgical removal of the carotid bodies, structures the size ... benefits for a surgical procedure known as bilateral carotid body resection (BCBR). The United States District Court for the ... The Secretary has issued a formal ruling stating that she will not pay the costs of bilateral carotid body resection (BCBR) ...
Results: Carotid body tumors were the most common paragangliomas of the head and neck (34 cases). Glomus jugulare or glomus ... Results: Carotid body tumors were the most common paragangliomas of the head and neck (34 cases). Glomus jugulare or glomus ... Results: Carotid body tumors were the most common paragangliomas of the head and neck (34 cases). Glomus jugulare or glomus ... Results: Carotid body tumors were the most common paragangliomas of the head and neck (34 cases). Glomus jugulare or glomus ...
Carotid body tumor as a potential cause of paroxysmal hemicrania. 62 Zhuang C...Beeman B ...
23 were carotid body tumors (8 malignant), 2 vagal body tumors (1 malignant), 4 carotid aneurysms, and 2 were metastatic tumors ... there were 23 with carotid body tumors (CBT) (8 malignant), 2 with vagal body tumors (VBTs) (1 malignant), 4 with carotid ... Application of monitoring SjvO2 and refluxing pressure of the internal carotid artery in resection of carotid body tumors. ... Treatment of carotid-body tumor: a report of 111 surgery cases. Zhongguo Linchuang Yixue 2005; 12: 478-479 (Chinese).. ...
... which has gone on to become the worlds largest center for multidisciplinary treatment of patients with carotid body tumors, ... Innovation Description: Pre-treatment imaging for head and neck squamous cell carcinoma (HNSCC) is not tumor-specific, leading ... We developed and conducted a clinical trial to evaluate a tumor-specific radiotracer, zirconium-89 panitumumab, to detect HNSCC ... James Netterville creates the Parapharyngeal Tumor Center at VUMC, ...
Carotid Body Tumors Paraganglioma, Carotid Body Paragangliomas, Carotid Body Tumor, Carotid Body Tumors, Carotid Body ... Carotid Body Tumors. Paraganglioma, Carotid Body. Paragangliomas, Carotid Body. Tumor, Carotid Body. Tumors, Carotid Body. ... Carotid Body Tumor Entry term(s). Carotid Body Paraganglioma Carotid Body Paragangliomas ... Carotid Body Tumor - Preferred Concept UI. M0003547. Scope note. Benign paraganglioma at the bifurcation of the COMMON CAROTID ...
  • Paraganglioma benigno en la bifurcación de las ARTERIAS CARÓTIDAS COMUNES. (bvsalud.org)
  • Benign paraganglioma at the bifurcation of the COMMON CAROTID ARTERIES . (bvsalud.org)
  • glomus tumor or paraganglioma of the carotid body. (myebr.org)
  • paraganglioma with the same signal characteristics as the carotid body paraganglioma but is located more superiorly at the skull base and may extend into the jugular foramen. (myebr.org)
  • Computed tomography (CT) scanning of the head and neck is also helpful and typically reveals a hypervascular tumor located between the external and internal carotid arteries. (medscape.com)
  • Also called "blood vessels," veins and arteries are vital structures that bring blood to every part of the body. (healthonecares.com)
  • Vascular disease can impact the veins and arteries that carry oxygen and nutrients to all the cells in your body. (healthonecares.com)
  • Enhancing soft tissue tumor splaying the internal and external carotid arteries. (myebr.org)
  • It characteristically splays the internal and external carotid arteries. (myebr.org)
  • Our qualified and highly committed team of vascular surgeons treat vascular diseases involving arteries and veins in the body except those around heart and brain. (karnataka.gov.in)
  • The carotid arteries provide the main blood supply to your brain. (medlineplus.gov)
  • When the arteries become blocked, the heart has to beat harder to pump blood around the body. (eatverts.com)
  • An ischemic stroke typically results from blockage of an artery that supplies blood to the brain, most commonly a branch of one of the internal carotid arteries. (msdmanuals.com)
  • The internal carotid arteries and the basilar artery divide into several branches, including the cerebral arteries. (msdmanuals.com)
  • Some branches join to form a circle of arteries (circle of Willis) that connect the vertebral and internal carotid arteries. (msdmanuals.com)
  • The body can also protect itself against strokes by growing new arteries. (msdmanuals.com)
  • Alcoholism allergy-triggered asthma arteries and veins astringents beta cells canine teeth controller medications corticosteroids dislocation eardrum epiglottis fiber glycosylated hemoglobin test (hemoglobin a1c) heat exhaustion hydrocortisone intensive care unit junk food occupational therapist oncologist radiologist saliva tinnitus vitreous body. (forthospitals.com)
  • Carotid body tumors (CBTs) are rare neoplasms, although they represent about 50-60% of head and neck paragangliomas. (medscape.com)
  • When choosing treatment, consider the following factors: the presence of other paragangliomas, the presence of bilateral carotid body tumors (CBTs), the age and the health of the patient, and the patient's preference. (medscape.com)
  • [ 9 ] Carotid body tumors (CBTs) constitute about 50-60% of head and neck paragangliomas. (medscape.com)
  • Glomus tumors - also known as paragangliomas - of the head and neck are benign (noncancerous) but locally invasive tumors that arise from glomus cells. (upmc.com)
  • When such tumors arise outside of the adrenal gland, they are termed extra-adrenal pheochromocytomas, or paragangliomas. (medscape.com)
  • Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors originating from the chromaffin cells of the autonomic nervous system. (medscape.com)
  • In the case of paragangliomas, the gene does not result in the development of tumors when maternally inherited. (elsevier.com)
  • Results: Carotid body tumors were the most common paragangliomas of the head and neck (34 cases). (elsevier.com)
  • It is recommended that all individuals in kindreds with paragangliomas be screened after the age of 16 years to detect early asymptomatic tumors. (elsevier.com)
  • Among the features that suggest a malignant course are large tumor size and an abnormal DNA ploidy pattern (aneuploidy, tetraploidy). (medscape.com)
  • Of the 31 cases, 23 were carotid body tumors (8 malignant), 2 vagal body tumors (1 malignant), 4 carotid aneurysms, and 2 were metastatic tumors from the cervix involving carotid artery. (cancerbiomed.org)
  • In the 31 cases, there were 23 with carotid body tumors (CBT) (8 malignant), 2 with vagal body tumors (VBTs) (1 malignant), 4 with carotid aneurysms, and 2 with metastatic cancer from the cervix involving carotid artery. (cancerbiomed.org)
  • In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes. (icd10data.com)
  • The term 'schwannoma', first introduced in 1935 by Stout, identifies a benign tumour with sporadic malignant degeneration arising from cranial, peripheral and autonomic nerve sheath cells [ 1 ]. (biomedcentral.com)
  • Liposarcomas are a rare, malignant cancer of the fatty tissue that can occur anywhere in the body. (medscape.com)
  • Cardiovascular disorders, malignant tumors, and erectile dysfunction are common complications of smoking in the Egyptian population. (who.int)
  • Tobacco smoking is a prevalent health problem in Egypt, associated with cardiovascular disorders and malignant tumors. (who.int)
  • [ 1 ] These tumors develop within the adventitia of the medial aspect of the carotid bifurcation. (medscape.com)
  • Situated at the left common carotid artery bifurcation. (myebr.org)
  • As the nation's leading provider of Gamma Knife procedures, UPMC has treated more than 12,000 patients with tumors, vascular malformations, pain, and other functional problems. (upmc.com)
  • Tumor excision combined with carotid artery resection (TECCAR) was conducted after an accurate testing of valid cerebral blood supply and compensation. (cancerbiomed.org)
  • Head and neck tumors with carotid artery involvement remain a problem for surgical treatment because a ligation or excision of the affected carotid artery may result in severe cerebrovascular complications (CVCs), even death. (cancerbiomed.org)
  • Patients were divided into 2 groups: carotid body tumor resection alone (CBTR) and carotid body tumor resection with preoperative arterial embolization (CBETR). (qxmd.com)
  • OBJECTIVE To summarize our clinical experience in treating 31 patients with neck masses undergoing carotid artery resection without arterial anastomosis (vascular reconstruction) in Tianjin Cancer Hospital during a period from 1979 to 2002. (cancerbiomed.org)
  • In the United States, the earliest successful carotid body tumor resection was performed by Scudder in 1903. (medscape.com)
  • Of the 31 cases, subtotal tumor resection was performed in 22. (cancerbiomed.org)
  • Hayes Martin, in his textbook of head and neck tumors, recommended against resection of any tumor that is now considered a Shamblin type III (see Staging). (medscape.com)
  • The retinal tumors are often quiescent at the time that the pineal tumor is discovered, and show no evidence of metastatic spread after enucleation of the globes. (thejns.org)
  • Incidental synchronous [99mTc] HYNIC-TOC avid lesion of the neck in a patient with metastatic melanoma: a metastatic lymph node or a carotid body tumor masquerading as a lymph node? (ac.ir)
  • In January, 1979, the Secretary issued an administrative instruction to all fiscal intermediaries that no payment is to be made for Medicare claims arising out of a surgical procedure known as bilateral carotid body resection (BCBR) when performed to relieve respiratory distress. (justia.com)
  • Preoperative embolization and postoperative complications of carotid body tumors]. (qxmd.com)
  • Surgical complications, primarily cranial nerve palsies, were more frequent for tumors larger than 5 cm in diameter. (elsevier.com)
  • In the head and neck, glomus tumor tissue is found in the jugular bulb, middle ear, and carotid artery. (upmc.com)
  • Of these sites, tumors are most common in the jugular bulb, which is a region of the jugular vein positioned immediately below the middle ear. (upmc.com)
  • Symptoms of glomus tumors depend on their location: middle ear, jugular bulb, deep neck, or carotid artery. (upmc.com)
  • Gamma Knife radiosurgery is a painless procedure that uses hundreds of highly focused radiation beams to target tumors and lesions within the brain, with no surgical incision. (upmc.com)
  • Innovation Description: Pre-treatment imaging for head and neck squamous cell carcinoma (HNSCC) is not tumor-specific, leading to detection of incidental lesions requiring unnecessary intervention and delay in treatment. (vumc.org)
  • We developed and conducted a clinical trial to evaluate a tumor-specific radiotracer, zirconium-89 panitumumab, to detect HNSCC lesions. (vumc.org)
  • Understand the current management for patients with carotid body tumors and high carotid lesions. (vascular.org)
  • MIOT International executed a highly advanced hybrid treatment strategy, to defuse the multiple brain aneurysms arising from the carotid artery of a 39-year-old Mauritian woman. (miotinternational.com)
  • The sporadic form is the most common type, representing approximately 85% of carotid body tumors (CBTs). (medscape.com)
  • Magnetic resonance imaging (MRI) is considered to be the criterion standard for carotid body tumors (CBTs), and the tumor has a characteristic salt and pepper appearance on T1-weighted images. (medscape.com)
  • Carotid body tumors (CBTs) are treated with either surgery or radiotherapy. (medscape.com)
  • however, carotid body tumors (CBTs) are considered to be a disease of middle age. (medscape.com)
  • Carotid body tumors (CBTs) are rare entities for which surgical resection remains the gold standard. (qxmd.com)
  • Common locations for extra-adrenal pheochromocytomas include the organ of Zuckerkandl (close to the origin of the inferior mesenteric artery), bladder wall, heart, mediastinum, and carotid and glomus jugulare bodies. (medscape.com)
  • Descriptions of surgery for carotid body tumors have existed for over 100 years. (medscape.com)
  • Carotid body tumor surgery: management and outcomes in the nation. (qxmd.com)
  • Impact of preoperative embolization on the outcomes of carotid body tumor surgery: A meta-analysis and review of the literature. (qxmd.com)
  • Surgery for carotid body tumor treatment, The patient experience: At Yashoda, I. (yashodahospitals.com)
  • Complete removal of the tumor and the involved carotid artery so as to improve the curative effect remains a clinical problem in the field of head and neck oncologic surgery and urgently needs to be resolved. (cancerbiomed.org)
  • Since the success of the first case of a neck mass in the carotid artery undergoing TECCAR without vascular reconstruction in our hospital in 1979, this type of surgery has been conducted in 31 patients until April, 2002. (cancerbiomed.org)
  • The patients were required to perform an exercise of applying pressure to the carotid artery before the planned carotid artery resection so as to thoroughly open the Circle of Willis and, as a result, to meet the blood supply requirements of the affected carotid during the surgery. (cancerbiomed.org)
  • The two year anniversary of the surgery to remove the tumor was November 26, 2009. (sir5r.com)
  • Glomus tumors of the head and neck are slow-growing, benign tumors. (upmc.com)
  • Glomus tympanicum tumors are the most common vascular tumors of the middle ear. (upmc.com)
  • Glomus tumors are highly vascular and usually solitary. (upmc.com)
  • Angiograms - Because of their vascular nature, your doctor may also order an angiogram to confirm the diagnosis of glomus tumors. (upmc.com)
  • Maintaining vascular health is critical for continued proper blood flow to the heart and the rest of the body. (healthonecares.com)
  • i ) The traditional operational technique, performs a conventional vascular repair after removal of the tumor and carotid artery in order to restore the normal blood supply. (cancerbiomed.org)
  • Pathologically, the pineal tumor is indistinguishable from the ocular retinoblastoma. (thejns.org)
  • At UPMC, the preferred treatment is a transmastoid surgical approach to remove the tumor. (upmc.com)
  • Ultrasound Evaluation of Carotid Body Tumor CME Vital provides an overview of normal carotid artery anatomy and physiology. (gcus.com)
  • It also provides an ultrasound evaluation of a carotid body tumor. (gcus.com)
  • He ordered a neck/carotid Ultrasound, and a Holter Monitor test. (sir5r.com)
  • For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned. (icd10data.com)
  • 1 Common tumour sites include the carotid body in the head and neck and adrenal and extra-adrenal paraganglia in the abdomen. (bmj.com)
  • Germline loss of function mutations followed by somatic loss of non-mutant alleles in the tumours 2- 4 suggests a tumour suppressor role for mitochondrial complex II in the paraganglia. (bmj.com)
  • [ 13 , 14 ] Patients with a genetic predisposition often present younger and, particularly if identified from surveillance because of a known familial germline mutation, are more likely to be asymptomatic compared with those with sporadic tumors. (medscape.com)
  • When these blood vessels become damaged or clogged, oxygen-rich blood does not circulate the body as needed. (healthonecares.com)
  • A pheochromocytoma (see the image below) is a rare, catecholamine-secreting tumor derived from chromaffin cells. (medscape.com)
  • Various imaging studies can be used to confirm the diagnosis of carotid body tumor (CBT), starting with simple ultrasonography with color Doppler. (medscape.com)
  • Various imaging studies can be used to confirm the diagnosis of carotid body tumor (CBT), starting with simple ultrasonography with color Doppler, which can assess the vascularity of the neck mass and can sometimes reveal a possibility of a carotid body tumor (CBT), although it is not the best imaging modality to detect these tumors. (medscape.com)
  • The specific locations of these tumors are usually sufficient for a diagnosis. (upmc.com)
  • Diagnosis: Carotid body tumor. (myebr.org)
  • With regard to laboratory studies, check urinary catecholamines in patients who have any symptoms of a functional carotid body tumor (CBT). (medscape.com)
  • Common symptoms of glomus tumors are hearing loss and facial palsies. (upmc.com)
  • All patients with liposarcoma of the thyroid have a rapidly growing tumor in the neck, but other symptoms may include dysphagia, respiratory distress (including dyspnea and shortness of breath), alterations in the voice (eg, hoarseness), globus sensation, weight loss, coughing, and deafness in one or both ears. (medscape.com)
  • VALUE RFVF 10050 ='Chills' 10100 ='Fever' 10120 ='Other symptoms of body temperature' 10121 ='Feeling cold' 10122 ='Feeling hot' 10123 ='Feeling hot and cold' 10150 ='Tiredness, exhaustion' 10200 ='General weakness' 10250 ='General ill feeling' 10300 ='Fainting (syncope)' 10350 ='Symptoms of fluid abnormalities' 10351 ='Edema' 10352 ='Excessive sweating, perspiration' 10353 ='Excessive thirst' 10400 ='Weight gain' 10450 ='Weight loss' 10451 ='Recent weight loss' 10452 ='Underweight' 10460 ='Symptoms of face, not elsewhere class. (cdc.gov)
  • Symptoms occur suddenly and may include muscle weakness, paralysis, lost or abnormal sensation on one side of the body, difficulty speaking, confusion, problems with vision, dizziness, and loss of balance and coordination. (msdmanuals.com)
  • Measles symptoms such as fever, erythematous maculopapular rashes on whole body and cough with sputum appeared 4 days before neurologic signs such as agitation and drowsy-to-confused mentality. (e-cep.org)
  • Uveitis is an inflammatory eye disease affecting the iris, ciliary body, and choroid that can lead to symptoms ranging from redness, pain, and blurred vision to markedly diminished acuity in the setting of severe or chronic disease. (touchophthalmology.com)
  • Surgical resection remains the treatment of choice since the very first experiences [ 10 - 13 ], even vagal nerve injury is still an unsolved problem, given the fact that the tumour originates directly from the nerve fibres. (biomedcentral.com)
  • The carotid body, which originates in the neural crest, is important in the body's acute adaptation to fluctuating concentrations of oxygen, carbon dioxide, and pH. (medscape.com)
  • Heart diseases, carcinoma, chronic pulmonary diseases, Alzheimer's disease, pneumonia and influenza are all linked with this enzyme that is produced by our body.1 This enzyme is called 5-lipoxygenase or 5-LOX for short, which, when generated by the body in excessive amounts, gives rise to a whole cascade of dangerous inflammatory reactions. (our-arthritis.com)
  • A growing body of evidence supports the relationships of OSA with increased cardiovascular morbidity and mortality, and OSA has been considered to be an independent risk factor for cardiovascular diseases[4, 5]. (docksci.com)
  • In this case, they would connect the saphenous vein graft to the carotid artery in the neck, pass it under the skin, and sew it to the middle cerebral artery inside the head. (bidmc.org)
  • O f necessity a textbook is always out-of-date by the time that it is produced, and as a consequence, carotid balloons and filters placed as cerebral protection devices during angioplasty are not discussed. (coek.info)
  • These glomus tumors may grow into the middle ear and brain. (upmc.com)
  • Brain tumor or other growth (mass). (medlineplus.gov)
  • As you all may be aware of in very simple terms the brain is made of grey matter (comprising the cell bodies of the neurons) and white matter (fiber tracts). (braindiseases.blog)
  • He has also been an invited faculty member at various conferences, including Teleradiology in IRIA 2008 and 2011, Hospital Build Middle East, Congress of the Brain Tumor Radiology in Neuro-oncology Society. (indianradiology.com)
  • WHO brain tumour classification has been updated in 2016. (indianradiology.com)
  • A retrospective study by Davila et al suggested that carotid body tumors also tend to appear at a younger age in patients with succinate dehydrogenase mutations (see Pathophysiology). (medscape.com)
  • In 16 (42%) of the patients there were multiple tumors. (elsevier.com)
  • METHODS Preoperatively, patients were instructed to apply pressure to the carotid artery. (cancerbiomed.org)
  • Multidisciplinary management of carotid body tumors: a single-institution case series of 22 patients. (cornell.edu)
  • Conclusions This meta-analysis suggested that CPAP therapy has no impact on adiponectin in OSA patients, without significant changes in body weight. (docksci.com)
  • Adhd allergy allergy-triggered asthma biopsy cone contact lenses depression dna fatty acids laxatives lymph node otitis media retinopathy urinalysis urine vitreous body. (forthospitals.com)
  • Larger tumors may compress the trachea and esophagus, resulting in hoarseness and difficulty swallowing. (upmc.com)
  • spread of tumor along these conduits can occur from the orbit to extraorbital compartments including intracranial extension. (radiologykey.com)
  • This activity was presented at VAM2019 as part of the Clinical Update of the P1: Carotid and Great Vessel Disease Management session. (vascular.org)
  • People with kidney disease or diabetes may need to receive extra fluids after the test to help flush the iodine out of the body. (medlineplus.gov)
  • Thyroid disease, such as hyperthyroidism, which causes the body to produce too much thyroid hormone, is a common cause of hormonal imbalance. (eatverts.com)
  • Imaging studies - Glomus tumors of the head and neck are diagnosed primarily through MRI and CT scans. (upmc.com)
  • The newest scanners can image your entire body, head to toe, in less than 30 seconds. (medlineplus.gov)
  • These tumors are considered unresectable, and radiation therapy is not good surgical candidates, both methods have not been medically proven. (berea.edu)
  • Impact of preoperative embolization on outcomes of carotid body tumor resections. (qxmd.com)
  • The 2016 World Health Organization Classification of Tumors of the Central Nervo. (indianradiology.com)
  • Perioperative approach in the surgical management of carotid body tumors. (qxmd.com)
  • Preoperative angiography and transarterial embolization in the management of carotid body tumor: a single-center, 10-year experience. (qxmd.com)
  • The low host resistance of trilateral retinoblastoma is evident by the early age of presentation, the multicentric occurrence of the tumor, and the high early mortality rate despite aggressive management. (thejns.org)
  • A course on radiotherapeutic management of Hepato-Pancreatico-Biliary Tumors was conducted on 23rd and 24th April at MIOT International, Chennai. (miotinternational.com)
  • Much of this increase is likely from incidental identification of tumors on imaging. (medscape.com)
  • NBE has introduced FNB for Interventional Radiology, Breast imaging and Body Imaging. (indianradiology.com)
  • There is an increasing recognition that adipose tissue is an endocrine organ secreting a number of biologically active adipokines such as leptin, adiponectin, and tumor necrosis factor-α. (docksci.com)
  • In the middle ear, most glomus tympanicum tumors present with hearing loss and pulsatile tinnitus and are found during a physical exam, appearing as a reddish-blue mass behind the eardrum. (upmc.com)
  • The Gamma Knife may be used as the first treatment option, particularly in cases where the tumor is not causing mass effect, or as an adjuvant treatment after partial removal of glomus tumors. (upmc.com)
  • Considering the location of the mass and the patient's MRI results, our strongest suspicion was that his neck swelling was caused by a retropharyngeal tumor - most likely a large lipoma or liposarcoma - given his unusual presentation. (medscape.com)
  • Subgroup analyses indicated that the results were not affected by age, baseline body mass index, severity of OSA, CPAP therapy duration, sample size and racial differences. (docksci.com)