A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Meprobamate has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated). It is used in the treatment of ANXIETY DISORDERS, and also for the short-term management of INSOMNIA but has largely been superseded by the BENZODIAZEPINES. (From Martindale, The Extra Pharmacopoeia, 30th ed, p603)
A centrally acting skeletal muscle relaxant whose mechanism of action is not completely understood but may be related to its sedative actions. It is used as an adjunct in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1202)
A heterogeneous group of drugs used to produce muscle relaxation, excepting the neuromuscular blocking agents. They have their primary clinical and therapeutic uses in the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. They have been used also for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in MULTIPLE SCLEROSIS. (From Smith and Reynard, Textbook of Pharmacology, 1991, p358)
Facilities equipped to carry out investigative procedures.
A CNS stimulant that is used to induce convulsions in experimental animals. It has also been used as a respiratory stimulant and in the treatment of barbiturate overdose.
Methods, procedures, and tests performed to diagnose disease, disordered function, or disability.
The branch of pharmacology that deals directly with the effectiveness and safety of drugs in humans.
Acute or chronic pain located in the posterior regions of the THORAX; LUMBOSACRAL REGION; or the adjacent regions.
Care provided patients requiring extraordinary therapeutic measures in order to sustain and prolong life.
Acute or chronic pain in the lumbar or sacral regions, which may be associated with musculo-ligamentous SPRAINS AND STRAINS; INTERVERTEBRAL DISK DISPLACEMENT; and other conditions.
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Disorders of sensory information received from superficial and deep regions of the body. The somatosensory system conveys neural impulses which pertain to proprioception, tactile sensation, thermal sensation, pressure sensation, and pain. PERIPHERAL NERVOUS SYSTEM DISEASES; SPINAL CORD DISEASES; and BRAIN DISEASES may be associated with impaired or abnormal somatic sensation.
Detection of drugs that have been abused, overused, or misused, including legal and illegal drugs. Urine screening is the usual method of detection.
Physicians appointed to investigate all cases of sudden or violent death.
Control of drug and narcotic use by international agreement, or by institutional systems for handling prescribed drugs. This includes regulations concerned with the manufacturing, dispensing, approval (DRUG APPROVAL), and marketing of drugs.
Certification as complying with a standard set by non-governmental organizations, applied for by institutions, programs, and facilities on a voluntary basis.
The guidelines and policy statements set forth by the editor(s) or editorial board of a publication.
An opioid analgesic related to MORPHINE but with less potent analgesic properties and mild sedative effects. It also acts centrally to suppress cough.
A private, voluntary, not-for-profit organization which establishes standards for the operation of health facilities and services, conducts surveys, and awards accreditation.

Carisoprodol: an unrecognized drug of abuse. (1/22)

During a 6-month monitoring period, carisoprodol was detected in the urine specimens of 19 patients for whom drug screening had been ordered for purposes of patient care. The clinical history suggested that in 7 cases the drug was abused or implicated in a suicide attempt or gesture. In another 7 cases, the drug was used primarily for medical purposes, and in 5 cases the reason for use could not be determined. One patient ingested homemade tablets that were found to contain carisoprodol. In an additional case, the drug was detected in breast milk. Physical findings, clinical history, and treatment are described, and the profile of a typical carisoprodol user is discussed. It seems that carisoprodol has become an unrecognized drug of abuse, at least in our community. This drug and its metabolite, meprobamate, should be included in comprehensive drug screening.  (+info)

Somatic dysfunction during carisoprodol cessation: evidence for a carisoprodol withdrawal syndrome. (2/22)

Carisoprodol is a commonly used skeletal muscle relaxant with potential for abuse because of its active metabolite, meprobamate, and several reports have suggested that patients abruptly stopping intake of carisoprodol may have a withdrawal syndrome. The authors studied changes in the occurrence of somatic dysfunctions in five patients during an 8-day period following discontinuation from large doses of carisoprodol. Results showed that the number of somatic dysfunctions changed significantly during the withdrawal period. Each patient had an increase in the number of somatic dysfunctions during the first 3 days after cessation of carisoprodol with return to at or near baseline by the eighth day. This was reflected statistically in a significant-within-subjects effect for time. Results of supplemental analyses revealed a significant component of the effect and a trend for the quadratic component to be significant. Increases in the number of somatic dysfunctions during carisoprodol discontinuation support the existence of a carisoprodol withdrawal syndrome.  (+info)

Simultaneous determination of carisoprodol and acetaminophen in an attempted suicide by liquid chromatography-mass spectrometry with positive electrospray ionization. (3/22)

An adult female ingested a considerable quantity of carisoprodol/acetaminophen tablets, which are not commercially available in Japan, in an attempt to commit suicide. Generally, because of lack of the appreciable ultraviolet absorbance or fluorescence, carisoprodol and its major metabolite meprobamate are determined by gas chromatography or gas chromatography-mass spectrometry. Complicated derivatization is, however, necessary to that methodology. Thus, we investigated the derivatization-free, highly sensitive, and simultaneous determination of carisoprodol, meprobamate, and acetaminophen by means of liquid chromatography-mass spectrometry (LC-MS) with positive electrospray ionization. A semi-micro ODS column was used. Ammonium acetate solution (10mM) and acetonitrile were used as mobile phase at a flow rate of 150 microL/min using gradient elution. MS parameters were as follows: capillary voltage, 3.5 kV; cone voltage, +30 V; extractor voltage, 5 kV; and ion source temperature, 100 degrees C. Urine samples pretreated by Oasis HLB cartridge, or plasma samples deproteinized by adding ice-cold acetonitrile were analyzed by LC-MS. The limits of quantitation for each compound were as follows: 0.50 ng/mL for carisoprodol; 10 ng/mL for acetaminophen; and 1.0 ng/mL for meprobamate. In the present case, carisoprodol and acetaminophen were the only drugs detected. Meprobamate was also found as the metabolite of carisoprodol in both urine and plasma. The plasma levels of carisoprodol, acetaminophen, and meprobamate on arrival were 29.5, 245, and 46.7 microg/mL, respectively. These levels were extremely high compared with therapeutic plasma concentrations. Despite the high plasma concentrations of these drugs, which correspond to fatal levels, the patient survived.  (+info)

Direct and rapid determination of baclofen (Lioresal) and carisoprodol (Soma) in bovine serum by liquid chromatography-mass spectrometry. (4/22)

Baclofen (Lioresal), a lipophilic analogue of c-aminobutyric acid (GABA), and carisoprodol (Soma), a central nervous system depressant with an unknown mechanism of pharmacologic action, are categorized as muscle relaxants. Baclofen is used clinically in the management of spasticity and its sequelae secondary to severe chronic disorders such as multiple sclerosis and other types of spinal cord lesions. Carisoprodol is used for discomfort associated with acute and painful musculoskeletal conditions. Intoxication from these drugs occurs in both humans and animals necessitating a need for their detection in plasma/serum, tissue, and gastrointestinal contents samples. A sensitive and specific analytical method for detection and quantitation of these compounds using liquid chromatography with positive atmospheric pressure chemical ionization-mass spectrometry was developed. A rapid extraction procedure for both analytes from fortified bovine sera is described. Chromatographic separation was carried out on a C(18) reverse-phase column with a gradient elution of acetonitrile and 0.25% acetic acid. The effluent was directed to the mass spectrometer with fragmentation information for baclofen and carisoprodol obtained in a scan monitoring mode. Linear standard curves for baclofen and carisoprodol were constructed based on at least two corresponding extracted ions over a concentration range of 0.1-50 micro g/mL. The analysis of fortified sera samples demonstrates good accuracy and precision for the method with a limit of detection of 0.5 micro g/mL for carisoprodol (n = 3) and 1 micro g/mL for baclofen (n = 4) and a limit of quantitation of 2 micro g/mL for both compounds. Recoveries at the limit of quantitation were between 75 and 95% for both analytes, with a 4.8-9.3% range in standard deviation.  (+info)

Identifying controlled substance patterns of utilization requiring evaluation using administrative claims data. (5/22)

OBJECTIVES: To develop a systems approach to identify, for further evaluation, patients with potential controlled substance misuse or mismanagement using software queries applied to administrative health claims data. STUDY DESIGN: Retrospective validation of the system using insurance claims. PATIENTS AND METHODS: Data from administrative health claims databases representing nearly 7 million individuals younger than 65 years were used by multidisciplinary expert panels to develop and validate controlled substance patterns of utilization requiring evaluation (CS-PURE) criteria. RESULTS: Thirty-four CS-PURE queries were developed in SAS and applied to administrative claims records to identify patients with potential controlled substance misuse or mismanagement. From these, we identified 10 CS-PURE with the highest expert agreement that intervention was warranted. Expert panel agree, ment that CS-PURE correctly identified cases ranged from 48% to 100%, with at least 50% agreement in 9 of 10 CS-PURE. The prevalence rates for CS-PURE ranged from 0.001% to 0.252%. This translates to identifying between 5 and 1116 patients for individual CS-PURE in a 500 000-member health plan. CONCLUSIONS: We developed and empirically validated a group of queries using CS-PURE to identify patients with potential controlled substance misuse or mismanagement that would warrant further evaluation by the treating physician, a quality assurance function, or the medical director. Claims-based CS-PURE identification is generalizable to most health insurers with access to medical and pharmaceutical claims records. Although CS-PURE are not direct measures of misuse, they can direct attention to potential problems to determine if intervention is needed.  (+info)

Carisoprodol use and abuse in Norway: a pharmacoepidemiological study. (6/22)

AIM: Carisoprodol was developed to create a drug with less potential for abuse than meprobamate. However, case reports have established carisoprodol as a drug of abuse. This paper explores the extent of potential abuse of this drug in Norway. METHODS: The Norwegian Prescription Database contains information on prescription drugs dispensed to individuals in Norway. Patients can be followed over time. High levels of carisoprodol use could indicate use for pleasurable effects or development of tolerance. Concomitant use of other potential drugs of abuse was also studied. We studied drug-seeking behaviour by looking at patients who received carisoprodol from many different pharmacies and doctors or from high-prescribing doctors. Carisoprodol was compared with a series of other medicinal drugs with or without known potential for abuse. RESULTS: Some 53,889 Norwegian women (2.4%) and 29,824 men (1.3%) > or =18 years old received carisoprodol at least once in 2004. Prescribing of carisoprodol was skewed. As many as 32% of the patients received more than 15 defined daily doses (DDDs) of carisoprodol and >11,000 patients (15%) received > or =75 DDDs in 2004. High users of carisoprodol also received more benzodiazepines and opioids. Few patients used three or more doctors for prescriptions, but carisoprodol-abusing patients more often received their prescription from high-prescribing doctors. CONCLUSIONS: Carisoprodol was widely used and the skewedness in use indicated that it is a potential drug of abuse. A large number of patients used more carisoprodol than recommended in the guidelines. The high level of use and abuse of carisoprodol should be of concern in Norway.  (+info)

Carisoprodol abuse in Texas, 1998-2003. (7/22)

INTRODUCTION: Texas poison centers identified carisoprodol as a skeletal muscle relaxant that is subject to abuse, and this investigation explores the abuse reported by Texas poison centers. METHODS: This study used data from six Texas poison centers to describe the epidemiology of carisoprodol abuse and drug identification (ID) calls from 1998 to 2003. RESULTS: Drug ID and abuse calls were 217% higher in 2003 than in 1998. Although eastern and central Texas contains 43% of the state's population, this region reported 77% of all drug ID calls and 64% of abuse calls. For male patients, 51% of the calls were abuse calls and 37% were other human carisoprodol exposure calls. Patients from 13 to 19 years of age accounted for 17% of abuse calls and 9% of other human exposure calls. Among those human exposure calls with a known medical outcome, a higher percentage of abuse calls involved minor effects while a greater proportion of other human exposure calls involved outcomes that ranged from moderate effects to death. CONCLUSIONS: Carisoprodol abuse is increasing in Texas and is substantially more common in the eastern part of the state. Carisoprodol abuse is much more likely, than other types of adverse carisoprodol exposures, to involve males and adolescents; and it less likely to involve adverse medical outcomes.  (+info)

Urine drug testing of chronic pain patients: licit and illicit drug patterns. (8/22)

Chronic pain patients are frequently maintained on one or more powerful opioid medications in combination with other psychoactive medications. Urine tests provide objective information regarding patient compliance status. Little information is available on testing this unique population. The goal of this study was to characterize drug disposition patterns in urine specimens collected from a large population of pain patients. Confirmation data for 10,922 positive specimens were collated into 11 drug Classes. The number of drug/metabolites tested (#) and number of confirmed positive specimens were as follows: amphetamines (7), 160; barbiturates (5), 308; benzodiazepines (6), 2397; cannabinoids (1), 967; carisoprodol (2), 611; cocaine (1), 310; fentanyl (1), 458; meperidine (2), 58; methadone (2), 1209; opiates (7), 8996; and propoxyphene (2), 385. Subdivision into 19 distinct drug Groups allowed characterization of drug use patterns. Of the 10,922 positive specimens, 15,859 results were reported as positive in various drug Classes, and 27,197 drug/metabolites were measured by gas chromatography-mass spectrometry. The frequency of illicit drug use (cannabis, cocaine, ecstasy) was 10.8%. Being the first study of this type, these data present a large array of information on licit and illicit drug use, drug detection frequencies, drug/metabolite patterns, and multi-drug use combinations in pain patients.  (+info)

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Scientific Literature Reports. The FDA review concluded that there are relatively few reports in the scientific literature describing fatal cases of intoxication with carisoprodol. The FDA further found that there are inconsistencies in the literature with regard to what is considered a toxic concentration level (17, 22, 28-31). As carisoprodol is frequently abused in combination with other drugs, the specific contribution of carisoprodol to a fatality may be difficult to ascertain.. [[Page 77350]]. However, several publications have attributed therapeutic levels of carisoprodol at 10-40 mg/l, toxic levels at 30-50 mg/l, and a lethal level at 110 mg/l (31-33).. Davis and Alexander (31) reviewed carisoprodol-related deaths in Jefferson County, Alabama, from January 1, 1986 to October 31, 1997. Of a total of 8,162 Medical Examiner cases, toxicology analysis found 24 cases in which carisoprodol was in the decedents blood. Blood carisoprodol concentrations in decedents ranged from ,1 mg/l to 96.8 ...
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Common brand names: Soma Compound with Codeine Summary of Interactions with Vitamins, Herbs, & Foods What Are Nutrient Interactions Types of interactions: Beneficial Adverse Check Replenish Depleted Nutrients Iron Gastrointestinal (GI) bleeding is a common side effect of taking aspirin. A person with aspirin-induced GI...
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  • The major metabolic pathway of carisoprodol involves its conversion to meprobamate. (wikipedia.org)
  • the euphoria derived is, according to new research, most likely due to carisoprodol's inherent, potent anxiolytic effects that are far stronger than those produced by its primary metabolite, meprobamate, which is often misblamed for the drug-seeking associated with carisoprodol, as carisoprodol itself is responsible for the significantly more intense CNS effects than meprobamate alone. (wikipedia.org)
  • Carisoprodol has a unique mechanism of action, qualitatively different from that of meprobamate (Miltown). (wikipedia.org)
  • Carisoprodol, meprobamate, and related drugs such as tybamate , have the potential to produce physical dependence of the barbiturate type following periods of prolonged use. (wikipedia.org)
  • tell your doctor and pharmacist if you are allergic to carisoprodol, meprobamate (Equanil, Meprospan, Miltown, Neuramate), any other medications, or any of the ingredients in carisoprodol tablets. (medlineplus.gov)
  • Carisoprodol Tablets are contraindicated in patients with a history of acute intermittent porphyria or a hypersensitivity reaction to a carbamate such as meprobamate. (nih.gov)
  • In nine subjects, carisoprodol was rapidly eliminated, with a mean half-life of 99 +/- 46 min, and extensively converted to meprobamate. (biopsychiatry.com)
  • Within 2.5 h after carisoprodol intake, meprobamate serum concentrations exceeded those of carisoprodol. (biopsychiatry.com)
  • Serum levels of meprobamate recorded (15-25 mumol/L) indicate that meprobamate might contribute to the effect(s) of carisoprodol. (biopsychiatry.com)
  • One subject eliminated carisoprodol with an overall half-life of 376 min, and only small amounts of meprobamate were recorded. (biopsychiatry.com)
  • You should not use this medication if you are allergic to carisoprodol, codeine, or meprobamate (Equanil, Miltown), or if you have ever had asthma or a severe allergic reaction to aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs). (cardiosmart.org)
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  • CYP2C19 poor metabolizers and patients receiving CYP2C19 inhibitors such as omeprazole may have higher concentrations of carisoprodol and lower concentrations of meprobamate. (rheumaknowledgy.com)
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  • Carisoprodol is similar to meprobamate as they both belong to the carbamate drug class and meprobamate is a clinically significant active metabolite of carisoprodol, although carisoprodol itself possesses additional antispasmodic properties which are distinct from its metabolites. (wikipedia.org)
  • These highlights do not include all the information needed to use CARISOPRODOL TABLETS safely and effectively. (nih.gov)
  • See full prescribing information for CARISOPRODOL TABLETS. (nih.gov)
  • Carisoprodol Tablets are indicated for the relief of discomfort associated with acute, painful musculoskeletal conditions in adults. (nih.gov)
  • The recommended maximum duration of carisoprodol tablets, USP use is up to two or three weeks. (nih.gov)
  • Side EffectsPregnancy / BreastfeedingDrug InteractionsDosageSupport Group Q & AUser Reviews Carisoprodol Prescribing Information Professional Monograph (FDA) Dosage Form: tablet Indications and Usage for Carisoprodol Carisoprodol tablets are indicated for the relief of discomfort associated with acute, painful musculoskeletal conditions in adults. (google.com)
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  • Carisoprodol Professional Information (A-Z Drug Facts) A-Z Drug Facts (Facts & Comparisons) Pronunciation: kar-EYE-soe-PROE-dolClass: Skeletal muscle relaxant, centrally actingTrade Names Soma - Tablets 250 mg - Tablets 350 mg Pharmacology Produces skeletal muscle relaxation, probably as result of its sedative properties. (google.com)
  • SOMA (carisoprodol) Tablets are available as 250 mg and 350 mg round, white tablets. (rxlist.com)
  • Use of carisoprodol, aspirin, and codeine tablets is not recommended in children younger than 12 years of age. (mayoclinic.org)
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  • Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of carisoprodol, aspirin, and codeine tablets in the elderly. (mayoclinic.org)
  • Soma Compound with Codeine (carisoprodol, aspirin, and codeine phosphate tablets) is indicated for the relief of discomfort associated with acute, painful musculoskeletal conditions in adults. (rxlist.com)
  • The recommended daily dose of Soma Compound with Codeine (carisoprodol, aspirin, and codeine phosphate tablets) is 1 or 2 tablets, four times daily in adults. (rxlist.com)
  • One Soma Compound with Codeine (carisoprodol, aspirin, and codeine phosphate tablets) tablet contains 200 mg of carisoprodol, 325 mg of aspirin, and 16 mg of codeine phosphate. (rxlist.com)
  • The maximum daily dose (i.e., two tablets taken four times daily) will provide 1600 mg of carisoprodol, 2600 mg of aspirin, and 128 mg of codeine phosphate per day. (rxlist.com)
  • Soma Compound with Codeine (carisoprodol, aspirin, and codeine phosphate tablets) (carisoprodol 200 mg, aspirin 325 mg, and codeine phosphate, 16 mg) Tablets are oval, convex, two-layered, and inscribed on the white layer with SOMA CC and on the yellow layer with WALLACE 2403. (rxlist.com)
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  • Determination of dissolved aspirin and carisoprodol Proceed as directed in the test for Dissolution under Carisoprodol and Aspirin Tablets . (drugfuture.com)
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  • Drugs.com Carisoprodol Pronunciation Class: Centrally Acting Skeletal Muscle Relaxants VA Class: MS200 CAS Number: 78-44-4 Brands: Soma, Soma Compound, Soma Compound with Codeine For Professionals Side Effects Dosage Interactions More. (google.com)
  • This dosage information may not include all the information needed to use Carisoprodol safely and effectively. (google.com)
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  • Carisoprodol may also be used for other purposes not listed in this medication. (google.com)
  • Aspirin and carisoprodol may also be used for purposes not listed in this medication guide. (rexhealth.com)
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  • or if you have where to buy carisoprodol 500mg in canada any other allergies.before using this medication, tell your doctor or pharmacist your medical history, especially of: apparently it is not often present in sufficient quantities to inducepoisoning, for although some cases of "tin poisoning" are met with in medicalliterature, in none of them has it been satisfactorily established that tin wasthe cause. (pexsummerfestival.com)
  • Carisoprodol, marketed under the brand name soma among others, is a medication used for musculoskeletal pain. (baza-leto.ru)
  • Carisoprodol causes muscle relaxation, sedation, and carisoprodol can be an effective medication in the treatment of various injuries and. (baza-leto.ru)
  • Along with its benefits, this medication is not uncommon following recovery.Carisoprodol (soma) is a prescription drug used to relax muscles and help alleviate pain from muscle spasms.Carisoprodol (bulk discount) search for carisoprodol in your area. (baza-leto.ru)
  • Carisoprodol causes muscle relaxation, sedation, and carisoprodol can be an effective medication in the treatment of various injuries and.Abstractotherabstract: the combination of hydrocodone, carisoprodol, and alprazolam is subject to abuse. (baza-leto.ru)
  • Drug information on hycodan, hydromet, hydromide (homatropine and hydrocodone) includes drug pictures, side effects, drug interactions, directions for use.And distribute hydrocodone and carisoprodol were recently sentenced in federal hydrocodone and carisoprodol and for conspiring to fraudulently obtain controlled.Hydrocodone and acetaminophen combination is used to relieve pain severe enough to require opioid treatment and when other pain medicines did not work well enough or.Effects of carisoprodol. (baza-leto.ru)
  • Carisoprodol is a muscle relaxer that works by blocking pain sensations between the nerves and the brain. (cardiosmart.org)
  • Carisoprodol is a muscle relaxer that is legally prescribed for the treatment of pain due to muscle injury and muscle spasms. (addictionsearch.com)
  • Carisoprodol is a muscle relaxer commonly prescribed for the treatment of pain carisoprodol, sold under the brand names soma and vanadom, is often used with. (baza-leto.ru)
  • New from Cerilliant - a 1.0 mg/mL Certified Spiking Solution® of the skeletal muscle relaxant internal standard Carisoprodol-D 7 . (cerilliant.com)
  • Carisoprodol is a skeletal muscle relaxant sold under the trade names Soma and Sanoma. (cerilliant.com)
  • Carisoprodol is used together with rest and physical therapy to treat injuries and other painful musculoskeletal conditions. (google.com)
  • SOMA® (carisoprodol) is approved for the relief of discomfort associated with acute, painful musculoskeletal conditions such as backache. (soma250.com)
  • conditions': [{'display': 'Pain', 'slug': 'pain'}, {'display': 'Musculoskeletal Conditions', 'slug': 'musculoskeletal-conditions'}], 'meta_title': {'price_page_otc': 'Compare Carisoprodol / Aspirin Prices - GoodRx', 'side_effects_page': 'Carisoprodol / Aspirin Side Effects, Information and Pricing - GoodRx', 'medicare_seo_page': 'Carisoprodol / Aspirin Medicare Coverage and Co-Pay Details - GoodRx', 'price_page': 'Carisoprodol / Aspirin Prices and Carisoprodol / Aspirin Coupons - GoodRx', 'info_page': 'What is Carisoprodol / Aspirin? (goodrx.com)
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  • Carisoprodol , marketed under the brand name Soma among others, is a prescription drug marketed since 1959. (wikipedia.org)
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  • Carisoprodol - how long does this drug stay in your system--(for UA purposes). (drugs.com)
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  • Carisoprodol is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription. (rexhealth.com)
  • T he elimination of the muscle relaxant drug, carisoprodol, was examined in 10 healthy volunteers after an oral dose of 700 mg. (biopsychiatry.com)
  • With the issuance of this final rule, the Administrator of the Drug Enforcement Administration (DEA) places the substance carisoprodol, including its salts, isomers, and salts of isomers, whenever the existence of such salts, isomers, and salts of isomers is possible, into Schedule IV of the Controlled Substances Act (CSA). (usdoj.gov)
  • Pursuant to section 811(b), in March 1996, the Drug Enforcement Administration (DEA) requested from the Department of Health and Human Services (HHS) a scientific and medical evaluation of carisoprodol, and a recommendation as to whether it should be controlled. (usdoj.gov)
  • In February 1997, however, the U.S. Food and Drug Administration's (FDA) Drug Abuse Advisory Committee concluded that the then-available data did not support controlling carisoprodol. (usdoj.gov)
  • Before you take aspirin, carisoprodol, and codeine, tell your doctor if you have asthma or sulfite allergy, kidney or liver disease, a breathing disorder, a history of stomach ulcer or intestinal blockage, or a history of drug or alcohol addiction. (cardiosmart.org)
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  • Humans were not alone in using herbs as medicines: buy generic carisoprodol in uk Disadvantages of injections include potential pain or discomfort for the patient and the requirement of trained staff using aseptic techniques for administration. (sindicatohrbs.com.br)
  • Older adults should not usually take carisoprodol because it is not as safe or effective as other medications that can be used to treat the same condition. (medlineplus.gov)
  • Post your question or story about Carisoprodol and connect with others who have experience with the same medications. (medschat.com)
  • Chemically, carisoprodol is N-isopropyl-2-methyl-2-propyl-1,3propanediol dicarbamate and the molecular formula is C 12 H 24 N 2 O 4 , with a molecular weight of 260.33. (rxlist.com)
  • What is the most important information I should know about aspirin and carisoprodol? (rexhealth.com)
  • Aspirin and carisoprodol is a combination medicine used short-term to treat painful muscular conditions. (rexhealth.com)
  • What should I discuss with my healthcare provider before taking aspirin and carisoprodol? (rexhealth.com)
  • Tell your doctor if you are pregnant or if you become pregnant while taking aspirin and carisoprodol. (rexhealth.com)
  • Aspirin and carisoprodol can pass into breast milk and may harm a nursing baby. (rexhealth.com)
  • Aspirin and carisoprodol is not approved for use by anyone younger than 16 years, or older than 65 years. (rexhealth.com)
  • How should I take aspirin and carisoprodol? (rexhealth.com)
  • Aspirin and carisoprodol is usually taken 4 times per day. (rexhealth.com)
  • Do not take aspirin and carisoprodol for longer than 3 weeks. (rexhealth.com)
  • Ask your doctor how to safely stop using aspirin and carisoprodol. (rexhealth.com)
  • What should I avoid while taking aspirin and carisoprodol? (rexhealth.com)
  • Aspirin and carisoprodol may impair your thinking or reactions. (rexhealth.com)
  • Identification The retention times of the aspirin, carisoprodol, and codeine phosphate peaks in the chromatograms of the Assay preparations correspond to those of the Standard preparations obtained as directed in the Assay for aspirin and carisoprodol and limit of free salicylic acid and the Assay for codeine phosphate . (drugfuture.com)

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