Cariogenic agents. Medical search

Substances that promote DENTAL CARIES.

A polysaccharide-producing species of STREPTOCOCCUS isolated from human dental plaque.

A diet that contributes to the development and advancement of DENTAL CARIES.

Localized destruction of the tooth surface initiated by decalcification of the enamel followed by enzymatic lysis of organic structures and leading to cavity formation. If left unchecked, the cavity may penetrate the enamel and dentin and reach the pulp.

The clear, viscous fluid secreted by the SALIVARY GLANDS and mucous glands of the mouth. It contains MUCINS, water, organic salts, and ptylin.

Infections with bacteria of the genus STREPTOCOCCUS.

Organic chemistry methodology that mimics the modular nature of various biosynthetic processes. It uses highly reliable and selective reactions designed to "click" i.e., rapidly join small modular units together in high yield, without offensive byproducts. In combination with COMBINATORIAL CHEMISTRY TECHNIQUES, it is used for the synthesis of new compounds and combinatorial libraries.

Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.

The functions, behavior, and activities of bacteria.

A medical specialty concerned with the hypersensitivity of the individual to foreign substances and protection from the resultant infection or disorder.

The study of microorganisms such as fungi, bacteria, algae, archaea, and viruses.

Summarizing techniques used to describe the pattern of mortality and survival in populations. These methods can be applied to the study not only of death, but also of any defined endpoint such as the onset of disease or the occurrence of disease complications.

Techniques used in microbiology.

A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.

A plant genus of the family POLYGONACEAE that is used as an EDIBLE GRAIN. Although the seeds are used as cereal, the plant is not one of the cereal grasses (POACEAE).

The practice of personal hygiene of the mouth. It includes the maintenance of oral cleanliness, tissue tone, and general preservation of oral health.

A combination of the debris index and the dental calculus index to determine the status of oral hygiene.

Any preparations used for cleansing teeth; they usually contain an abrasive, detergent, binder and flavoring agent and may exist in the form of liquid, paste or powder; may also contain medicaments and caries preventives.

Solutions for rinsing the mouth, possessing cleansing, germicidal, or palliative properties. (From Boucher's Clinical Dental Terminology, 4th ed)

A family of the order Anura, distinguished by the lack of a tongue. It includes four living genera of aquatic "toads". Two of the most familiar pipids are the popularly called Surinam "toad" (Pipa pipa) and XENOPUS LAEVIS.

Exclusive legal rights or privileges applied to inventions, plants, etc.

The science dealing with the establishment and maintenance of health in the individual and the group. It includes the conditions and practices conducive to health. (Webster, 3d ed)

Group composed of associates of same species, approximately the same age, and usually of similar rank or social status.

A form of interactive entertainment in which the player controls electronically generated images that appear on a video display screen. This includes video games played in the home on special machines or home computers, and those played in arcades.

Recording of visual and sometimes sound signals on magnetic tape.

A publication issued at stated, more or less regular, intervals.

A quantitative measure of the frequency on average with which articles in a journal have been cited in a given period of time.

The evaluation by experts of the quality and pertinence of research or research proposals of other experts in the same field. Peer review is used by editors in deciding which submissions warrant publication, by granting agencies to determine which proposals should be funded, and by academic institutions in tenure decisions.

An organized procedure carried out by a select committee of professionals in evaluating the performance of other professionals in meeting the standards of their specialty. Review by peers is used by editors in the evaluation of articles and other papers submitted for publication. Peer review is used also in the evaluation of grant applications. It is applied also in evaluating the quality of health care provided to patients.

Inorganic compounds that contain chlorine as an integral part of the molecule.

A greenish-yellow, diatomic gas that is a member of the halogen family of elements. It has the atomic symbol Cl, atomic number 17, and atomic weight 70.906. It is a powerful irritant that can cause fatal pulmonary edema. Chlorine is used in manufacturing, as a reagent in synthetic chemistry, for water purification, and in the production of chlorinated lime, which is used in fabric bleaching.

An offensive, foul breath odor resulting from a variety of causes such as poor oral hygiene, dental or oral infections, or the ingestion of certain foods.

Inorganic or organic compounds that contain sulfur as an integral part of the molecule.

Binary compounds of oxygen containing the anion O(2-). The anion combines with metals to form alkaline oxides and non-metals to form acidic oxides.

Substances used on inanimate objects that destroy harmful microorganisms or inhibit their activity. Disinfectants are classed as complete, destroying SPORES as well as vegetative forms of microorganisms, or incomplete, destroying only vegetative forms of the organisms. They are distinguished from ANTISEPTICS, which are local anti-infective agents used on humans and other animals. (From Hawley's Condensed Chemical Dictionary, 11th ed)

Dentifrices that are formulated into a paste form. They typically contain abrasives, HUMECTANTS; DETERGENTS; FLAVORING AGENTS; and CARIOSTATIC AGENTS.

Restoration of integrity to traumatized tissue.

Epidermal cells which synthesize keratin and undergo characteristic changes as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell.

Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.

A novel composition, device, or process, independently conceived de novo or derived from a pre-existing model.

The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.

Property, such as patents, trademarks, and copyright, that results from creative effort. The Patent and Copyright Clause (Art. 1, Sec. 8, cl. 8) of the United States Constitution provides for promoting the progress of science and useful arts by securing for limited times to authors and inventors, the exclusive right to their respective writings and discoveries. (From Black's Law Dictionary, 5th ed, p1014)

The antisocial acts of children or persons under age which are illegal or lawfully interpreted as constituting delinquency.

The principles of proper professional conduct concerning the rights and duties of the dentist, relations with patients and fellow practitioners, as well as actions of the dentist in patient care and interpersonal relations with patient families. (From Stedman, 25th ed)

Voluntary groups of people representing diverse interests in the community such as hospitals, businesses, physicians, and insurers, with the principal objective to improve health care cost effectiveness.

Agents used to occlude dental enamel pits and fissures in the prevention of dental caries.

"Decayed, missing and filled teeth," a routinely used statistical concept in dentistry.

Practice of adding fluoride to water for the purpose of preventing tooth decay and cavities.

A species of gram-positive, coccoid bacteria isolated from the human tooth surface. Strains have been shown to be cariogenic in experimental animals and may be associated with human dental caries.

A resinous substance obtained from beehives that is used traditionally as an antimicrobial. It is a heterogeneous mixture of many substances.

A plant genus of the family LAURACEAE. Members contain cryptofolione, caryachine, grandisin and other compounds. Some PEUMUS species have been reclassified as CRYPTOCARYA.

A genus of gram-positive, coccoid bacteria whose organisms occur in pairs or chains. No endospores are produced. Many species exist as commensals or parasites on man or animals with some being highly pathogenic. A few species are saprophytes and occur in the natural environment.

A species of ACTINOMYCES found in the oral cavity of man and hamsters. It has been isolated from actinomycotic lesions in swine, cats, and dogs and has been identified as a causative agent of animal diseases.

Food starches and dental caries. (1/43)

Sucrose and starches are the predominant dietary carbohydrates in modern societies. While the causal relationship between sucrose and dental caries development is indisputable, the relationship between food starch and dental caries continues to be debated and is the topic of this review. The current view of dental caries etiology suggests that in-depth evaluation of the starch-caries relationship requires the consideration of several critical cariogenic determinants: (1) the intensity (i.e., the amount and frequency) of exposure of tooth surfaces to both sugars and starches, (2) the bioavailability of the starches, (3) the nature of the microbial flora of dental plaque, (4) the pH-lowering capacity of dental plaque, and (5) the flow rate of saliva. Studies of caries in animals, human plaque pH response, and enamel/dentin demineralization leave no doubt that processed food starches in modern human diets possess a significant cariogenic potential. However, the available studies with humans do not provide unequivocal data on their actual cariogenicity. In this regard, we found it helpful to distinguish between two types of situations. The first, exemplified by our forebears, people in developing countries, and special subject groups in more modern countries, is characterized by starch consumption in combination with a low sugar intake, an eating frequency which is essentially limited to two or three meals per day, and a low-to-negligible caries activity. The second, exemplified by people in the more modern societies, e.g., urban populations, is characterized by starch consumption in combination with significantly increased sugar consumption, an eating frequency of three or more times per day, and a significantly elevated caries activity. It is in the first situation that food starches do not appear to be particularly caries-inducive. However, their contribution to caries development in the second situation is uncertain and requires further clarification. Although food starches do not appear to be particularly caries inducive in the first situation, the possibility cannot be excluded that they contribute significantly to caries activity in modern human populations. The commonly used term "dietary starch content" is misleading, since it represents a large array of single manufactured and processed foods of widely varying composition and potential cariogenicity. Hence, increased focus on the cariogenicity of single starchy foods is warranted. Other aspects of starchy foods consumption, deserving greater attention, include the bioavailability of starches in processed foods, their retentive properties, also in relation to sugars present (starches as co-cariogens), their consumption frequency, the effect of hyposalivation on their cariogenicity, and their impact on root caries. The starch-caries issue is a very complex problem, and much remains uncertain. More focused studies are needed. At present, it appears premature to consider or promote food starches in modern diets as safe for teeth. (+info)

Modern methods for assessing the cariogenic and erosive potential of foods. (2/43)

Assessment of the acidogenic and cariogenic erosive potential of foods requires the use of reproducible and standardised methods. The methodology laid down at the San Antonio conference in 1985 remain today the basis for research on and the testing of foods. The 1999 workshop has updated the appropriate methodology and introduced guidelines on the testing of erosive potential of foods. It is to be hoped that researchers wishing to evaluate foods and their effect on the teeth will continue to use these methods. (+info)

Intake of sweet foods and counts of cariogenic microorganisms in obese and normal-weight women. (3/43)

OBJECTIVE: To study the intake of sweet foods in obese and normal-weight women, while also taking menstrual cycle effects on eating behaviour into consideration. An objective test of the intake of sugar-containing foods was introduced by measuring salivary counts of mutans streptococci and lactobacilli. DESIGN: A cross-sectional comparison of the intake of sweet foods in obese and normal-weight women. The obese women were also studied longitudinally after 10 weeks in a weight reduction programme. SUBJECTS: Obese (n=72, body mass index (BMI) 42.0+/-5.2 kg/m2) and normal-weight women (n=67, BMI 22.2+/-1.6 kg/m2) participated. RESULTS: Mutans streptococci in saliva were higher in obese than in normal-weight women (P<0.0001), although the reported habitual daily intake of sweet foods did not differ. Of the menstruating women, 80% of the obese subjects and 62% of the normal-weight ones (P<0.05) reported periods during the menstrual cycle with an 'extra large' intake of sweet foods; these intakes were higher in obese than in normal-weight women (P<0.01). The obese women reduced their intake of sweet foods after 10 weeks of weight reduction, although these changes were not pronounced enough to significantly affect the counts of cariogenic microorganisms. CONCLUSIONS: In contrast to most previous cross-sectional studies, this study shows that obese women have a higher intake of sweet foods, especially pre-menstrually. This was indicated by higher salivary counts of cariogenic microorganisms. SPONSORSHIP: Karolinska Institute Research Funds. (+info)

A mixed-bacteria ecological approach to understanding the role of the oral bacteria in dental caries causation: an alternative to Streptococcus mutans and the specific-plaque hypothesis. (4/43)

For more than 100 years, investigators have tried to identify the bacteria responsible for dental caries formation and to determine whether their role is one of specificity. Frequent association of Lactobacillus acidophilus and Streptococcus mutans with caries activity gave credence to their being specific cariogens. However, dental caries occurrence in their absence, and the presence of other bacteria able to produce substantial amounts of acid from fermentable carbohydrate, provided arguments for non-specificity. In the 1940s, Stephan found that the mixed bacteria in dental plaque produced a rapid drop in pH following a sugar rinse and a slow pH return toward baseline. This response became a cornerstone of plaque and mixed-bacterial involvement in dental caries causation when Stephan showed that the pH decrease was inversely and clearly related to caries activity. Detailed examination of the pH (acid-base) metabolisms of oral pure cultures, dental plaque, and salivary sediment identified the main bacteria and metabolic processes responsible for the pH metabolism of dental plaque. It was discovered that this metabolism in different individuals, in plaque in different dentition locations within individuals, and in individuals of different levels of caries activity could be described in terms of a relatively small number of acid-base metabolic processes. This led to an overall bacterial metabolic vector concept for dental plaque, and helped unravel the bacterial involvement in the degradation of the carbohydrate and nitrogenous substrates that produce the acids and alkali that affect the pH and favor and inhibit dental caries production, respectively. A central role of oral arginolytic and non-arginolytic acidogens in the production of the Stephan pH curve was discovered. The non-arginolytics could produce only the pH fall part of this curve, whereas the arginolytics could produce both the fall and the rise. The net result of the latter was a less acidic Stephan pH curve. Both kinds of bacteria are numerous in dental plaque. By varying their ratios, we were easily able to produce Stephan pH curves indicative of different levels of caries activity. This and substantial related metabolic and microbial data indicated that it is the proportions and numbers of acid-base-producing bacteria that are at the core of dental caries activity. The elimination of S. mutans, as with a vaccine, was considered to have little chance of success in preventing dental caries in humans, since, in most cases, this would simply make more room for one or more of the many acidogens remaining. An understanding of mixed-bacterial metabolism, knowledge of how to manipulate and work with mixed bacteria, and the use of a bacterial metabolic vector approach as described in this article have led to (1) a more ecological focus for dealing with dental caries, and (2) new means of developing and evaluating anti-caries agents directed toward microbial mixtures that counter excess acid accumulation and tooth demineralization. (+info)

Do we need to be concerned about dental caries in the coming millennium? (5/43)

Dental caries continues to be a pubic health problem despite claims that 50% of schoolchildren are caries-free. There are widespread variations in the prevalence of caries worldwide. Caries lesions are the clinical manifestation of a pathogenic process that may have been occurring on the tooth surface for months or years. Acid production by bacteria embedded in a biofilm termed "dental plaque" is a key aspect of the pathogenesis of dental caries; nevertheless, the ability of micro-organisms to survive in a hostile acid milieu and the influence of fluoride and additional agents on this acid tolerance receive scant attention. Study of cariogenic micro-organisms largely has been limited to observations made on them in the planktonic state; clearly dental caries is essentially a surface phenomenon, and micro-organisms behave distinctively when grown on a surface. Although significant progress has been made in our understanding of the etiology, pathogenesis, and prevention of dental caries, it still remains a scientific and clinical enigma worthy of the attention of the best scientists. (+info)

Effect of a Brazilian regional basic diet on the prevalence of caries in rats. (6/43)

The aim of the present study was to determine the effect of a regional basic diet (RBD) on the prevalence of caries in the molar teeth of rats of both sexes aged 23 days. The animals were divided into six groups of 10 rats each receiving the following diets for 30 and 60 days after weaning: RBD, a cariogenic diet, and a commercial diet. The prevalence and penetration of caries in the molar teeth of the rats was then analyzed. The RBD produced caries in 37.5% of the teeth of animals fed 30 days, and in 83.4% of animals fed 60 days, while the cariogenic diet produced caries in 72.5% and 77.5% of the teeth of animals fed 30 and 60 days, respectively. Rats fed the RBD for 30 days had caries in the enamel in 38% of their teeth, 48% had superficial dentin caries, and 7.5% moderate dentin caries. The effect of the RBD did not differ significantly from that of the cariogenic diet in terms of the presence of caries in rats fed 60 days. The penetration depth of the caries produced by the RBD was the same as that produced by the cariogenic diet. Our results show that the RBD has the same cariogenic potential as the cariogenic diet. Since the RBD is the only option for the low-income population, there should be a study of how to compensate for the cariogenicity of this diet. (+info)

Genome sequence of Streptococcus mutans UA159, a cariogenic dental pathogen. (7/43)

Streptococcus mutans is the leading cause of dental caries (tooth decay) worldwide and is considered to be the most cariogenic of all of the oral streptococci. The genome of S. mutans UA159, a serotype c strain, has been completely sequenced and is composed of 2,030,936 base pairs. It contains 1,963 ORFs, 63% of which have been assigned putative functions. The genome analysis provides further insight into how S. mutans has adapted to surviving the oral environment through resource acquisition, defense against host factors, and use of gene products that maintain its niche against microbial competitors. S. mutans metabolizes a wide variety of carbohydrates via nonoxidative pathways, and all of these pathways have been identified, along with the associated transport systems whose genes account for almost 15% of the genome. Virulence genes associated with extracellular adherent glucan production, adhesins, acid tolerance, proteases, and putative hemolysins have been identified. Strain UA159 is naturally competent and contains all of the genes essential for competence and quorum sensing. Mobile genetic elements in the form of IS elements and transposons are prominent in the genome and include a previously uncharacterized conjugative transposon and a composite transposon containing genes for the synthesis of antibiotics of the gramicidin/bacitracin family; however, no bacteriophage genomes are present. (+info)

Composition of dental plaque formed in the presence of sucrose and after its interruption. (8/43)

Since dental plaque reservoirs of fluoride (F), calcium (Ca) and inorganic phosphorus (Pi) are susceptible to decreases in pH, this in situ crossover study was conducted to test the hypothesis that the low concentration of these ions in plaque, formed in the presence of sucrose, could be attributed merely to the fermentation of this sugar. Eleven volunteers wore palatal appliances containing 6 human enamel blocks during two stages. In each stage, the treatments were either 20% sucrose solution or distilled deionized water, which were dripped onto the blocks 8 times a day. After 28 days, in each stage, the dental plaque formed on two blocks was collected, the treatment was inverted and after a further 24 and 48 h, the biofilm formed was collected from the other blocks. The concentration of acid-soluble F, Ca and Pi, and the concentration of insoluble polysaccharide (IP) were determined in the dental plaque. Statistically lower concentrations of F, Ca and Pi, and a higher concentration of IP were found in the 28-day biofilm formed in the presence of sucrose than in its absence; after the treatment inversion the change in F, Ca and Pi was not statistically significant, but the IP concentration changed significantly. The hypothesis was rejected because change in concentration of F, Ca and Pi is not due to fermentation of the sucrose. (+info)

2006). "Correlation of cariogenic bacteria and dental caries in adults". Journal of Oral Science. 48 (4): 245-251. doi:10.2334/ ... Saliva containing more buffering agents such as calcium and phosphate ions alter the internal environment of dental plaque to ... No specific organisms had been identified at that point that were more cariogenic than others. Thus the amount of plaque in ... Despite this, the hypothesis was useful in diagnosis and treatment, associating caries with such truly cariogenic bacteria as ...

https://en.wikipedia.org/wiki/Plaque_hypotheses

This results in a cariogenic biofilms at the interface of composite and tooth. The cariogenic activity of bacteria increases ... A coupling agent such as silane is used to enhance the bond between these two components. An initiator package (such as: ... Researchers are highlighting the need for new composite materials to be developed which eliminate the cariogenic products ... BisHPPP has furthermore been shown to regulate bacterial genes, making bacteria more cariogenic, thus compromising the ...

https://en.wikipedia.org/wiki/Dental_composite

To prevent this, nano-hydroxyapatite can be added to the bleaching solution to reduce the impact of the bleaching agent by ... In the event of an acid attack by cariogenic bacteria, nano-hydroxyapatite particles can infiltrate pores on the tooth surface ... Teeth bleaching agents release reactive oxygen species which can degrade enamel. ... to reverse damage from carious assaults by either directly replacing deteriorated surface minerals or acting as a binding agent ...

https://en.wikipedia.org/wiki/Hydroxyapatite

By preventing the dental plaque biofilm from maturing or by returning it back to a non-cariogenic state, dental caries can be ... Enzymes that degrade the biofilm matrix may be useful as anti-biofilm agents. Evidence has shown that a fatty acid messenger, ... An ecologic shift away from balanced populations within the dental biofilm is driven by certain (cariogenic) microbiological ... Lewis K (April 2001). "Riddle of biofilm resistance". Antimicrobial Agents and Chemotherapy. 45 (4): 999-1007. doi:10.1128/AAC. ...

https://en.wikipedia.org/wiki/Biofilm

The amine fluorides are thus available as an active agent for a longer period. Amine fluorides have a slightly acidic pH. For ... This acts as a fluoride depot over a longer period: Under cariogenic conditions fluoride ions are made available stimulating ... "Further Studies on the Influence of Surface Active Agents on Decalcification of the Enamel Surface". Journal of Dental Research ...

https://en.wikipedia.org/wiki/Amine_fluoride

... cariogenic agents MeSH D27.720.102.223 - cariostatic agents MeSH D27.720.102.339 - dental materials MeSH D27.720.102.583 - ... antiviral agents MeSH D27.505.954.122.388.077 - anti-retroviral agents MeSH D27.505.954.122.388.077.088 - anti-hiv agents MeSH ... tocolytic agents MeSH D27.505.954.016 - anti-allergic agents MeSH D27.505.954.122 - anti-infective agents MeSH D27.505.954.122. ... tranquilizing agents MeSH D27.505.696.277.950.015 - anti-anxiety agents MeSH D27.505.696.277.950.025 - antimanic agents MeSH ...

https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D27)

It is oxidised to menthone by oxidising agents such as chromic acid or dichromate, though under some conditions the oxidation ... "Antibacterial Activity of Essential Oils and Their Isolated Constituents against Cariogenic Bacteria: A Systematic Review". ... Menthol is widely used in dental care as a topical antibacterial agent, effective against several types of streptococci and ... and more generally as a food flavor agent; such as in chewing gum and candy. As a pesticide against tracheal mites of honey ...

https://en.wikipedia.org/wiki/Menthol

The causative agent of dental caries is associated with its ability to metabolize various sugars, form a robust biofilm, ... This therefore amplifies the cariogenic effect of S.mutans. Oral streptococci have both harmless and harmful bacteria. However ... Surviving in the oral cavity, S. mutans is the primary causal agent and the pathogenic species responsible for dental caries ( ... ISBN 978-1-904455-24-0. Hoshino T, Fujiwara T, Kawabata S (2012). "Evolution of cariogenic character in Streptococcus mutans: ...

https://en.wikipedia.org/wiki/Streptococcus_mutans

Treatment with other topical agents, such as calcium phosphate (CPP-ACP), may also be effective in the remineralization of ... that the formation of pits and missing enamel provides a suitable local environment for adhesion and colonization of cariogenic ...

https://en.wikipedia.org/wiki/Enamel_hypoplasia

The influence of various conditioning agents on the interdiffusion zone and microleakage of a glass ionomer cement with a high ... suggestive that enough fluoride release may decrease the virulence of cariogenic biofilms. In addition, Ngo et al. (2006) ... they were mainly used for the restoration of abrasion/erosion lesions and as a luting agent for crown and bridge ... can determine whether the cement is used as luting agents, orthodontic bracket adhesives, pit and fissure sealants, liners and ...

https://en.wikipedia.org/wiki/Glass_ionomer_cement

They are usually used in conjunction with a bonding agent as they have no ability to bond to the tooth, although there are some ... Although classified as non-cariogenic by the Food and Drug Administration, eugenol is proven to be cytotoxic with the risk of ... Composition: Phosphoric acid liquid Zinc Oxide powder Formerly known as the most commonly used luting agent. Zinc Phosphate ... these etch the tooth surface and do not require an intermediate bonding agent Resin cements come in a range of shades to ...

https://en.wikipedia.org/wiki/Dental_cement

Use as a topical fluoride agent on moderate and high-risk patients, especially children aged 5 and younger Desensitizing agent ... Fluoride varnish treatments are shown to reduce the number of the cariogenic bacteria S. Mutans by over ten-fold. Fluoride ... They are recognised by the Food and Drug Administration for use as desensitising agents, but, currently, not as an anti-decay ... Chokshi, Krunal (2016). "An in vitro Comparative Evaluation of Three Remineralizing Agents using Confocal Microscopy". Journal ...

https://en.wikipedia.org/wiki/Fluoride_varnish

Antimicrobial Agents and Chemotherapy. 60 (1): 356-360. doi:10.1128/AAC.01194-15. PMC 4704196. PMID 26525789. Khan, Shahper N; ... "A graphene/zinc oxide nanocomposite film protects dental implant surfaces against cariogenic Streptococcus mutans". Biofouling ... Antimicrobial Agents and Chemotherapy. 52 (11): 4115-4120. doi:10.1128/AAC.00366-08. PMC 2573143. PMID 18725447. He, X (2003 ... Antimicrobial Agents and Chemotherapy. 53 (12): 5046-5054. doi:10.1128/aac.00774-09. ISSN 0066-4804. PMC 2786356. PMID 19770275 ...

https://en.wikipedia.org/wiki/Asad_Ullah_Khan

Yee et al (2009) compared the effectiveness of 38% against 12% SDF, with or without using a reducing agent for the caries ... Similarly, the silver in SDF kills cariogenic bacteria by interacting with DNA and cellular proteins. This leads to cessation ... Savas S, Kucukyılmaz E, Celik EU, Ates M (2015). "Effects of different antibacterial agents on enamel in a biofilm caries model ... A new anti-caries agent". primary. Journal of Materials Science. Materials in Medicine. 25 (8): 2041-7. doi:10.1007/s10856-014- ...

https://en.wikipedia.org/wiki/Silver_diammine_fluoride

... is an effective antimicrobial agent and is used as an antibacterial agent in reducing bacterial microflora in ... Jyoti S, Shasikiran ND, Reddy VV (2009). "Effect of lactoperoxidase system containing toothpaste on cariogenic bacteria in ... Agents Chemother. 23 (2): 267-72. doi:10.1128/aac.23.2.267. PMC 186035. PMID 6340603. Sipe HJ, Jordan SJ, Hanna PM, Mason RP ( ... Finally lactoperoxidase may find application as anti-tumor and anti viral agents. Lactoperoxidase has been used with ...

https://en.wikipedia.org/wiki/Lactoperoxidase

Fluoride varnishes were developed late 1960s and early 1970s and since then they have been used both as a preventative agent in ... Oral hygiene practices involve the mechanical removal of plaque from hard tissue surfaces Cariogenic bacteria levels in the ... "The Role of Remineralizing Agents in dentistry: A Review". Volume 32, Number 6. 2011. retrieved on 2016-05-22. Moynihan, Paula ... for enamel regeneration or as an oral care agent. It has a high affinity to tooth mineral. P11-4 is a self-assembling β-peptide ...

https://en.wikipedia.org/wiki/Remineralisation_of_teeth

Agents Chemother. 23 (2): 267-72. PMC 186035. PMID 6340603. doi:10.1128/aac.23.2.267.. ... Jyoti S, Shasikiran ND, Reddy VV (2009). "Effect of lactoperoxidase system containing toothpaste on cariogenic bacteria in ... Thomas EL, Bates KP, Jefferson MM (September 1980). "Hypothiocyanite ion: detection of the antimicrobial agent in human saliva ... "Challenge testing the lactoperoxidase system against a range of bacteria using different activation agents". J. Dairy Sci. 91 ( ...

https://gl.wikipedia.org/wiki/Lactoperoxidase

2003). "The genome sequence of Clostridium tetani, the causative agent of tetanus disease". Proc. Natl. Acad. Sci. U.S.A. 100 ( ... 2002). "Genome sequence of Streptococcus mutans UA159, a cariogenic dental pathogen". Proc. Natl. Acad. Sci. U.S.A. 99 (22): ... mycoides SC type strain PG1T, the causative agent of contagious bovine pleuropneumonia (CBPP)". Genome Res. 14 (2): 221-7. doi: ... 2004). "The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae". ...

https://en.wikipedia.org/wiki/List_of_sequenced_bacterial_genomes

A teratogen is "any agent that can potentially cause a birth defect or negatively alter cognitive and behavioral outcomes." ... colonization of cariogenic bacteria primarily occurs from mother to child through saliva-sharing activities. Maternal oral ...

https://en.wikipedia.org/wiki/Maternal_health

Hypothiocyanite ion: detection of the antimicrobial agent in human saliva. . In: J Dent Res. . 59, Nr. 9, September 1980, S. ... Effect of lactoperoxidase system containing toothpaste on cariogenic bacteria in children with early childhood caries. . In: J ... Challenge testing the lactoperoxidase system against a range of bacteria using different activation agents. . In: J. Dairy Sci. ...

https://de.wikipedia.org/wiki/Lactoperoxidase

However, cariogenic bacteria (the ones that can cause the disease) are present in dental plaque, but they are usually in too ... Low concentration fluoride ions act as bacteriostatic therapeutic agent and high concentration fluoride ions are bactericidal. ... Sucrose, although a bound glucose and fructose unit, is in fact more cariogenic than a mixture of equal parts of glucose and ... Over time, a mature biofilm is formed and this create a cariogenic environment on the tooth surface. The minerals in the hard ...

https://en.wikipedia.org/wiki/Tooth_decay

... such as the sedative agent used and whether a rubber dam was used. The success rate of root canal treatment also depends on the ... the majority of cases could be prevented by avoidance of a cariogenic diet and maintenance of good oral hygiene. That is, ...

https://en.wikipedia.org/wiki/Toothache

You have to register before you can post on our forums or use our advanced features. Register Now! Its Free and Fast!. Already registered? Login now below.. ...

http://molecularstation.com/cariogenic-agents/

... mutans from dental biofilms using broad-spectrum antimicrobial agents is not practical, because these agents inevitably result ... Genome sequence of Streptococcus mutans UA159, a cariogenic dental pathogen. Proc. Natl. Acad. Sci. U. S. A. 99:14434-14439. ... Antimicrobial Agents and Chemotherapy Oct 2011, 55 (11) 5205-5213; DOI: 10.1128/AAC.05175-11 ... Antimicrobial Agents and Chemotherapy Oct 2011, 55 (11) 5205-5213; DOI: 10.1128/AAC.05175-11 ...

https://aac.asm.org/content/55/11/5205?ijkey=47a885d81433b163f91c2d8993f759a0535efce8&keytype2=tf_ipsecsha

... mutans genotypes isolated in vivo under controlled conditions of high cariogenic challenge. This study evaluated … ... Cariogenic Agents / administration & dosage* * Cross-Over Studies * Dental Deposits / microbiology * Genetic Variation / ... Genotypic and phenotypic analysis of S. mutans isolated from dental biofilms formed in vivo under high cariogenic conditions ... The present results suggest that biofilms formed under high cariogenic conditions may harbor more aciduric and acidogenic S. ...

https://pubmed.ncbi.nlm.nih.gov/21861023/

Degradation of dentin-bonded interfaces treated with collagen cross-linking agents in a cariogenic oral environment: An in ... Comments Off on Degradation of dentin-bonded interfaces treated with collagen cross-linking agents in a cariogenic oral ... To provide a cariogenic challenge in all four specimens, each of the volunteers was instructed to remove the device and drip in ... 1 ). Teeth were then randomized by lottery and distributed within the different levels of the cross-linking agents ( n = 10 ...

https://pocketdentistry.com/degradation-of-dentin-bonded-interfaces-treated-with-collagen-cross-linking-agents-in-a-cariogenic-oral-environment-an-in-situstudy/

Gram-positive cariogenic bacteria are important etiological agents in dental caries; therefore, strategies to inhibit these ... which are important Gram-positive cariogenic bacteria as well as ,italic,Streptococcus gordonii,/italic,, non-pathogenic oral ... Gold-titanate NPs demonstrated potential antimicrobial activity against Gram-positive cariogenic bacteria. These results ...

https://digital.lib.washington.edu/researchworks/handle/1773/26045

A. princeps may inhibit the cariogenic activity of S. mutans, and may be useful as an anticariogenic agent.May 31, 2019. ... β-caryophyllene may inhibit cariogenic biofilm and may be a candidate agent for prevention of dental caries.Mar 31, 2018. ... Tulsi has the potential to be developed into an antimicrobial agent against cariogenic bacteria, specifically S. mutans.Dec 31 ... Cranberry extracts inhibited cariogenic virulence properties of S. mutans-C. albicans dual-species biofilms in an in vitro ...

https://www.greenmedinfo.com/disease/steptococcus-mutans-infections

β-caryophyllene may inhibit cariogenic biofilm and may be a candidate agent for prevention of dental caries.Mar 31, 2018. ... Pharmacological Actions : Anti-Bacterial Agents, Antifungal Agents, Antioxidants. Additional Keywords : Antifungal Agents, ... Pharmacological Actions : Anti-Bacterial Agents. Additional Keywords : Anti-Bacterial Agents, Caryophyllene, Dental Plaque, ... Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective, Chemoprotective Agents. Additional Keywords : Cannabinoid ...

https://www.greenmedinfo.com/substance/beta-caryophyllene

Effectiveness of dentine bonding agents against cariogenic bacteria in vitro: a comparison of two methods pp. 140-143(4) ...

http://www.ingentaconnect.com/content/mksg/omi/2003/00000018/00000003

chemical agent Chlorhexidine as a mouthwash. Drug: Chlorhexidine chemical agent used as a mouthwash against cariogenic bacteria ... Anti-Bacterial Agents. Anti-Infective Agents, Local. Anti-Infective Agents. Disinfectants. Dermatologic Agents. ... Natural product : The leaves of the guava tree are full of antioxidants, anti-inflammatory agents, antibacterials, and even ...

https://clinicaltrials.gov/show/NCT03773094

... rinses and dentifrices containing one or more antimicrobial anti-plaque and anti-cariogenic agents. ... wherein the mouthwash further includes an anti-cariogenic agent comprising a dentally-acceptable fluoride soluble therein. ... All percents by weight for all additives such as the antimicrobial agents, the anti-plaque agents, the anticariogenic agents, ... at least one agent selected from the group consisting of an oral antimicrobial agent, an anti-plaque agent, an anticariogenic ...

http://www.google.com/patents/US6086856?dq=6702462

Therefore, Ru is a natural anti-cariogenic agent with anti-mutansucrase activity and antimicrobial activity against S. mutans. ... Kim, J., Nguyen, T.T.H., Jin, J. et al. Anti-cariogenic Characteristics of Rubusoside. Biotechnol Bioproc E 24, 282-287 (2019 ... Ru inhibited the growth of S. mutans as a bacteriostatic agent, with MIC and MBC values of 6 mM and 8 mM, respectively. In ... To explore the anti-cariogenic characteristics of rubusoside (Ru), a natural sweetener component in Rubus suavissimus S. Lee ( ...

https://rd.springer.com/article/10.1007/s12257-018-0408-0?error=cookies_not_supported&error=cookies_not_supported&code=3b247261-d50a-4154-955d-97712f5f25b5

Non-lethal control of the cariogenic potential of an agent-based model for dental plaque. ... Here we employ agent-based mathematical modelling to simulate a biofilm consisting of two competing, distinct types of ... The MBC-P for the antimicrobial agent is defined as the lowest concentration of drug that kills the cells in the planktonic ... For the biofilm assay, the media is refreshed with fresh media lacking the antimicrobial agent and the biofilm cells are left ...

https://www.jove.com/visualize/abstract/25144538/non-lethal-control-cariogenic-potential-an-agent-based-model-for

... anti-gingivitis and anti-periodontitis agent, and also effective to destroy malodorous sulfur compounds. Preferred ... Chlorine dioxide is an effective anti-plaque agent, ... retardant or preventative and as an anti-cariogenic agent. ... Chlorine dioxide is an effective anti-plaque agent, anti-gingivitis and anti-periodontitis agent, and also effective to destroy ... Chlorine dioxide is an effective anti-plaque agent, anti-gingivitis and anti-periodontitis agent, and also effective to destroy ...

http://www.google.com/patents/US4689215?dq=6,232,546

Caesalpinia sappan: A promising natural source of antimicrobial agent for inhibition of cariogenic bacteria Rinrampai Puttipan ...

https://www.jstage.jst.go.jp/browse/ddt

Mutanolysin, bacteriolytic agent for cariogenic Streptococci: partial purification and properties.. *Koichi Yokogawa, Sanae ...

https://www.semanticscholar.org/topic/mutanolysin/114742

Streptococcus mutans is considered as a major cariogenic agent in oral cavity. This bacteria can synthetize soluble and ... Cardiovasc Hematol Agents Med Chem. 2019 Jan 14. BUY Concentrated Propolis in Veggie Capsules BUY 3-Piece (2 Fountain Pens, ... Beeswax by-Products Efficiently Counteract the Oxidative Damage Induced by an Oxidant Agent in Human Dermal Fibroblasts. Int J ... The result of the reviewed article showed that propolis is effective an agent that is used for multiple purpose in oral health ...

http://apitherapy.blogspot.com/2019/01/

... a potential ecological role for cranberry phenols as non-bactericidal agents capable of modulating pathogenicity of cariogenic ...

https://www.dentistry.co.uk/2019/01/08/nutrients-cranberries-blueberries-prevent-tooth-decay/?utm_content=84363769&utm_medium=social&utm_source=twitter&hss_channel=tw-123067935

Cariogenic Agents, Sweetening Agents, Dental Plaque, CARIES PREVENTION, SUGAR SUBSTITUTES, PLAQUE PH, CONSUMPTION, RATS, ... Analysis of the data suggests that lactose-containing stevioside sweeteners may be cariogenic, especially to dentin. ...

https://www.gu.se/forskning/publikation?publicationId=214435

For example, the effectiveness of the commonly utilized antiplaque agent triclosan against cariogenic S. mutans could be ... This agent has been utilized previously to quantitate the export of drugs from bacteria (15). Both the bip and smbG mutants ... bip and smbG gene expression in the presence of antimicrobial agents.A role for bacteriocin immunity proteins in resistance to ... Such a large increase might reflect the weak expression of the bip gene in the absence of exogenous antimicrobial agents. In ...

https://jb.asm.org/content/188/23/8095?ijkey=693927ffe8f4b0ca7d036175aaa800a37d408aad&keytype2=tf_ipsecsha

We demonstrated that these agents in combination severely compromise EPS-matrix assembly and cariogenic biofilm development, ... We demonstrated that these agents in combination severely compromise EPS-matrix assembly and cariogenic biofilm development, ... We will focus on increasing the kinetics of NPC pH-responsive drug release to ensure maximal release of the agents at pH ... We will focus on increasing the kinetics of NPC pH-responsive drug release to ensure maximal release of the agents at pH ...

https://www.urmc.rochester.edu/labs/benoit/news.aspx?start=01-01-2016&end=12-31-2016

Other applications for oligosaccharides such as an anti-cariogenic agent or a low sweetness humectant have also been explored. ...

http://patents.com/us-20170101484.html

download aftershock protect yourself been with retained agent gene strategies is cariogenic and electric liver and control. ... The levels was then study recommended personnel quantified via 1000 & of cariogenic download aftershock protect yourself and ... and the agent of Downstream Targets. These, only, are also the special and dental days. download aftershock protect yourself ...

http://prigsbee.com/Hawaii/freebooks/download-aftershock%3A-protect-yourself-and-profit-in-the-next-global-financial-meltdown.htm

... such a skilled artisan may provide anti-cariogenic and anti-demineralizing agents such as fluoride salts, more particularly ... anti-acne agents, anti-caking agents, antifoaming agents, antimicrobial agents, antioxidants, binders, biological additives, ... anti-inflammatory agents, anti-cellulite agents, topical anesthetics, tanning compounds, skin lightening agents, skin healing ... opacifying agents, pH adjusters, propellants, reducing agents, sequestrants, skin bleaching and lightening agents (e.g., ...

http://www.freepatentsonline.com/8524771.html

Xylitol, a 5-carbon naturally occurring sugar alcohol, is a proven anti-caries agent. The cariogenic bacteria ingest the ... Antimicrobial agents provide a bacterial load reduction and give the commensal bacterial an opportunity to re-establish control ... Chlorhexidine has been a standard anti-microbial agent, although it has little effect on Lactobacillus. Sodium hypochlorite in ... an oral rinse works as a rapid broad spectrum antimicrobial agent.. * ...

https://carifree.com/2015/10/27/10-more-tips-on-cambra/

... without the presence of cariogenic bacterial agents. Upper premolar are the most frequently affected teeth. More than 90% of ... Although abrasion and acid erosion have been the most widely considered etiological agents for many years, they are not able to ...

https://www.teses.usp.br/teses/disponiveis/23/23161/tde-16022021-180007/fr.php

... or anti-cariogenic properties is disclosed. The process comprises preparing said products with, or adding thereto a saccharide ... or anti-cariogenic property, as well as to sweeten them. ... a favoring agent; or a coloring agent.. Unlike sucrose, the ... Theuse of such saccharides realizes a low-cariogenic sweetener, but does not provide anti-cariogenic food products directed to ... Attorney Or Agent:. Browdy and Neimark. U.S. Class:. 131/274; 424/48; 424/49; 424/56; 424/57; 424/64; 426/3; 426/590; 426/658; ...

http://www.patentgenius.com/patent/4518581.html

X. Xu, X. D. Zhou and C. D. Wu, "The tea catechin epigallocatechin gallate suppresses cariogenic virulence factors of ... Streptococcus mutans," Antimicrobial Agents and Chemotherapy, Vol. 55, No. 3, 2011, pp. 1229-1236. ...

http://scirp.org/journal/paperinformation.aspx?paperid=6356

Int J Antimicrob Agents 26:343-356. [ Links ]. Dye BA, Tan S, Smith V, Lewis BG, Barker LK, Thornton-Evans G, Eke PI, Beltrán- ... Biological action of propolis on cariogenic bacteria. S. mutans and S. sobrinus were clinical samples obtained from children of ... Biological action on cariogenic bacteria. The analysis of results shows that a different propolis sample does not have the same ... Chemical and botanical characterization of Chilean propolis and biological activity on cariogenic bacteria Streptococcus mutans ...

https://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822013000200038

The structure of water-insoluble glucans of cariogenic Streptococcus mutans, formed in the absence and presence of dextranase. ... Molecular modeling study of highly branching (1--,3)-alpha-D-glucan, a model polysaccharide for cariogenic glucan, using the N- ... of the composition of glucans synthesized by enzymes of the cariogenic organism Streptococcus mutans. ...

https://www.meta.org/papers/the-structure-of-water-insoluble-glucans-of/4447949

... cariostatic mechanisms of specific cranberry phytochemicals and their potential use as therapeutic agents against cariogenic ... Cranberry phenols have the ability to disrupt these cariogenic virulence properties without being bactericidal, a key quality ... are known to have virulence attenuating effects against several cariogenic virulence properties responsible for dental caries ... cranberry A-type proanthocyanidins and flavonols have demonstrated potent inhibitory effects against cariogenic virulence ...

https://www.cranberryinstitute.org/cranberry-health-research/abstract/cranberry-polyphenols-natural-weapons-against-dental-caries

Gold-titanate NPs demonstrated potential antimicrobial activity against Gram-positive cariogenic bacteria. (washington.edu)
chemical agent used as a mouthwash against cariogenic bacteria. (clinicaltrials.gov)
Bacteria in biofilms frequently express much greater resistance to antimicrobial agents than they do in the corresponding planktonic cultures ( 5 ). (asm.org)
The cariogenic bacteria ingest the xylitol but cannot metabolize it. (carifree.com)
The aim of this study was to determine the chemical and botanical characterization of Chilean propolis samples and to evaluate their biological activity against the cariogenic bacteria Streptococcus mutans and Streptococcus sobrinus . (scielo.br)
This review discusses the cariostatic mechanisms of specific cranberry phytochemicals and their potential use as therapeutic agents against cariogenic bacteria in the prevention and control of dental caries. (cranberryinstitute.org)
ut oil's antibacterial efficacy, more research is needed to investigate its efficacy against the main cariogenic bacteria (Streptococcus mutans, Lactobasillus fermentum, and Streptococcus mitis) in comparison with its pure fatty acids and a commercially available mouth rinse, chlorhexidine. (tufts.edu)
Currently, the principal etiological agent initiating dental caries is known to involve cariogenic bacteria, oral streptococci (mostly Streptococcus mutans ), early stage carious lesions and lactobacilli from advanced lesions [ 1 , 3 , 4 ]. (medsci.org)
Based on the world attraction to traditional treatment and importance of drug extraction of natural material and plants , in this in vitro study effect of hydroalcoholic extract of Salvia officinalis and Menta longifolia which were very useful in traditional treatment of mouth and teeth disease has been determined against cariogenic bacteria . (bvsalud.org)
First, cariogenic bacteria cannot metabolize xylitol into acid, as they do many other carbohydrates and sweeteners, protecting the teeth from additional acid exposure. (carifree.com)
In our study, capsaicin was used to evaluate the antimicrobial property on the inhibition of acid producing and biofilm of Streptococcus mutans, Actinomyces viscosus , Lactobacillus and Streptococcus sanguis, which were sectional cariogenic bacteria, in order to search for new antimicrobial agents or treatment methods to cure or prevent dental caries. (thefreedictionary.com)
The present work selected four strains of cariogenic bacteria (Streptococcus mutans, Actinomyces viscosus , Lactobacillus and Streptococcus sanguis) as research objects. (thefreedictionary.com)
It was caused by various species of oral bacteria.The diagnosis includes detection of cariogenic bacteria. (omicsonline.org)
It can be prevented by preventing bacteria from the surface of the tooth and topical antimicrobial agents. (omicsonline.org)
Zoocin A has a potential antibacterial properties and its use as an anti-cariogenic agent needs to be explored Objective: Dental caries is an infectious disease, caused mainly by mutans streptococci (MS). The aim of the present study is to evaluate the antimicrobial effect of zoocin A on the biofilm producing cariogenic oral bacteria compared with antibiotics. (ui.ac.id)
the hydrophilic-rich phase could be infiltrated by oral fluids and cariogenic bacteria. (ku.edu)
Licorice has anti-bacterial agents that are great for fighting the bacteria attacking your teeth. (fogut.com)
Oral bacteria implying a natural resistance may deteriorate the antibacterial efficacy of chlorhexidine on cariogenic microorganisms. (quintpub.com)
In this course, the dynamic process of demineralization and remineralization is discussed, paying particular attention to tooth hard tissue structure, the role of acid production by cariogenic bacteria, and the critical pH at which tooth enamel begins to dissolve. (dentalcare.com)
Conclusion: Green tea has antibacterial activity against predominant cariogenic bacteria namely S. mutans and L. acidophilus. (jbclinpharm.org)
Titanate-metal complexes have] proven to be effective against endodontic, cariogenic and periodontic bacteria," Dr. Chung said. (washington.edu)
Thus, caries results from the interplay of three main factors over time: dietary carbohydrates, cariogenic bacteria within dental plaque, and susceptible hard tooth surfaces [ 3 ]. (prosestru.cz)
Fluoride's anti-caries efficacy is well-proven and may arise from multiple modes of action, i.e., inhibition of tooth demineralization, promotion of incipient lesion remineralization, and perhaps, antibacterial effects on cariogenic bacteria [ 9 ]. (prosestru.cz)
Increased amount of dental plaque containing cariogenic bacteria is the main etiologic factor in decalcification of enamel during orthodontic treatment. (intechopen.com)
CONCLUSION: Natural phytochemicals hold enormous potential as adjunctive therapeutic agents against cariogenic bacteria in the prevention and control of dental caries. (bvsalud.org)
2 Also, there is mounting international evidence that this decline is ending 3 and that many dental patients are still highly infected with cariogenic bacteria (105 Streptococcus mutans/mL of saliva). (oralhealthgroup.com)
It has the potential to remineralize, but might not change the patient's caries risk and may not offer optimal removal of cariogenic bacteria. (oralhealthgroup.com)
This is why, more than 12 years ago, I tried to identify a therapeutic agent able to control the disease and reduce the cariogenic bacteria load. (oralhealthgroup.com)
This therapeutic concentration was tested as an antibacterial agent to reduce the cariogenic bacteria load and as a therapeutic agent to prevent cavitated and non-cavitated carious lesions and as a remineralizer. (oralhealthgroup.com)
Many authors suggested medical strategies aimed at controlling cariogenic bacteria colonization instead of conventional approaches. (oralhealthgroup.com)
27-29 The presence of cariogenic bacteria has also been used successfully as a marker in risk assessment for any age, 29,30 as well as in monitoring the outcome of caries prevention. (oralhealthgroup.com)
11 In the end, cariogenic bacteria prevalence seems to affect the real efficacy of topical fluorides. (oralhealthgroup.com)
Modern Caries Process Considering Cariogenic Bacteria. (oralhealthgroup.com)
Fluoride toothpaste does not create significant antibacterial - conversion under the key threshold on cariogenic bacteria in high caries risk individuals. (oralhealthgroup.com)
Despite this, the hypothesis was useful in diagnosis and treatment, associating caries with such truly cariogenic bacteria as Streptococcus mutans and the lactobacilli species. (wikipedia.org)
The specific plaque hypothesis was introduced by Loesche, following on from observations that rodents did not develop caries even with a highly cariogenic diet unless specific bacteria such as streptococci were introduced. (wikipedia.org)
This study proposes a bioprospection methodology regarding the antimicrobial potential of plant extracts against bacteria with cariogenic relevance. (unesp.br)
The evidence presented in this study suggests that microwave irradiation is an effective disinfectant agent for bacteria and fungi on toothbrushes. (jispcd.org)

In this study, we constructed and evaluated a target-specific, salt-resistant antimicrobial peptide (AMP) that selectively targeted Streptococcus mutans , a leading cariogenic pathogen. (asm.org)
Xu, X., X. D. Zhou, and C. D. Wu (2011) The tea catechin epigallocatechin gallate suppresses cariogenic virulence factors of Streptococcus mutans . (springer.com)
Streptococcus mutans has been implicated as a primary causative agent of dental caries in humans ( 6 ). (asm.org)
We have evaluated the antimicrobial mode of action of these fractions on Streptococcus mutans, the etiological agent of human dental caries. (uva.nl)
The Gram-positive bacterium Streptococcus mutans is the principal causative agent of human tooth decay, an oral disease that affects the majority of the world's population. (edu.pl)
5. Jeon JG, Klein MI, Xiao J, Gregoire S, Rosalen PL, Koo H. Influences of naturally occurring agents in combination with fluoride on gene expression and structural organization of Streptococcus mutansin biofilms. (edu.pl)
Streptococcus mutans is the principal causative agent of dental caries in humans. (middlebury.edu)
Cariogenic microorganisms like Streptococcus mutans and Lactobacillus acidophilus encourage the accumulation and adherence of plaque biofilm by metabolizing sucrose into sticky glucan. (jbclinpharm.org)
Researchers from China and South Korea investigated if the ethanol extract of Artemisia princeps could inhibit the cariogenic activity of Streptococcus mutans . (medicine.news)
Halistanol sulfate A and rodriguesines A and B are antimicrobial and antibiofilm agents against the cariogenic bacterium Streptococcus mutans. (innovareacademics.in)
Cariogenic Streptococcus mutans Produces Tetramic Acid Strain-Specific Antibiotics That Impair Commensal Colonization. (escholarship.org)
Streptococcus mutans is a common constituent of dental plaque and a major etiologic agent of dental caries (tooth decay). (escholarship.org)
Streptococcus mutans is the primary etiological agent of human dental caries. (biomedcentral.com)

Although hundreds of species of microorganisms are isolated from dental biofilms, decades of studies in epidemiology, microbiology, biochemistry, and animal models have strongly implicated S. mutans as the primary etiological agent of dental caries worldwide ( 1 , 2 , 13 ). (asm.org)
However, little is known about the diversity and virulence traits of S. mutans genotypes isolated in vivo under controlled conditions of high cariogenic challenge. (nih.gov)
The present results suggest that biofilms formed under high cariogenic conditions may harbor more aciduric and acidogenic S. mutans genotypes. (nih.gov)
Ru inhibited the growth of S. mutans as a bacteriostatic agent, with MIC and MBC values of 6 mM and 8 mM, respectively. (springer.com)
Therefore, Ru is a natural anti-cariogenic agent with anti-mutansucrase activity and antimicrobial activity against S. mutans . (springer.com)
We further demonstrated that the inactivation of bip or smbG , another bacteriocin immunity protein gene present within the smb operon in S. mutans GS5, affected sensitivity to a variety of antimicrobial agents. (asm.org)
Similarly, the results from the agar-well diffusion method were statistically significant for S. mutans (p-value=0.003), Lactobacillus fermentum (p-value ≤S. mitis (p-value ≤Conclusion: Coconut oil has potential to be used as an antimicrobial agent in mouth rinses to reduce cariogenic microorganisms in the oral cavity. (tufts.edu)
Mutans streptococci is an established etiologic agent for caries, and its presence clearly indicates the potential for cariogenic activity. (intelligentdental.com)
The structural information obtained on these proteins can be used to select novel targets for the design of innovative therapeutic agents towards S. mutans. (edu.pl)
Articles addressing the effect of antimicrobial PDT with the use of a photosensitizing agent on known cariogenic biofilm formed mainly by streptococci of the mutans group and/or lactobacilli were included, with no restrictions placed on the method employed or year of publication. (thefreedictionary.com)
This research is important not only because it will advance our understanding of S. mutans gene regulation but also because it will reveal a basis for designing novel therapeutic agents that can target SloR-modulated virulence gene expression and so alleviate the S. mutans -induced cariogenic process. (middlebury.edu)
Microbiological investigations were carried out to determine the minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and zone of Inhibition of the test and control agents against S. mutans and L. acidophilus. (jbclinpharm.org)
Based on these findings, the researchers concluded that A. princeps can inhibit the cariogenic activity of S. mutans and may be useful as an anti-cariogenic agent . (medicine.news)
All the growth inhibitory natural agents tested showed similar inhibition for both S. mutans and S. sanguinis. (bvsalud.org)

Abstract: Aim: Due to the antiseptic characteristic of its main ingredients (monolauric and monocapric fatty acids), coconut oil poses a promising natural antibacterial alternative to chemically-based mouth rinses to fight cariogenic oral microorganisms. (tufts.edu)
Anita P, Sivasamy S, Madan Kumar PD, Balan IN, Ethiraj S. In vitro antibacterial activity of Camellia sinensis extract against cariogenic microorganisms. (jbclinpharm.org)
Use of antimicrobials is an important strategy to curb cariogenic microorganisms. (jbclinpharm.org)
3 ] An aberration to this ecology due to dietary habits, improper oral hygiene or systemic factors lead to an increase in cariogenic microorganisms. (jbclinpharm.org)
Hence, the use of the antimicrobial agent is warranted to limit the growth of cariogenic microorganisms and prevent dental caries. (jbclinpharm.org)
One strategy for controlling dental caries in patients with high levels of cariogenic microorganisms is their suppression by chemotherapeutic agents (1-3). (bvsalud.org)

This suggests a potential ecological role for cranberry phenols as non-bactericidal agents capable of modulating pathogenicity of cariogenic biofilms. (dentistry.co.uk)
Naturally occurring molecules as alternative therapeutic agents against cariogenic biofilms. (edu.pl)
METHODS: Saliva-derived polymicrobial biofilms were grown for 96 h in a cariogenic environment and treated every 12 h with 2% CPP-ACP or vehicle control. (bvsalud.org)

14. A method for imparting a low- or anti-cariogenic property to an orally-usable product containing sucrose as a sweetener, comprising incorporating into said product, a substance selected from the group consisting of isomaltosyl mono-, di-, ortri-glucose, reduction products thereof and mixtures thereof, in an amount, effective to impart such property to the product, of at least 5% on the dry solid basis. (patentgenius.com)
Among the major carbohydrates in the diet complex carbohydrates (e.g., starches) and simple sugars (e.g., sucrose and lactose) sucrose appears to have the greatest cariogenic potential. (nap.edu)
Since glucan -- a polymer of glucose derived from the metabolism of sucrose -- is a primary virulence factor that propels the change in microbial ecology that leads to a cariogenic plaque, it has been proposed that proteins that have the property of binding glucan play accessory roles in this process. (uiowa.edu)
Sucrose has been identified as the most cariogenic carbohydrate. (nih.gov)

Here we employ agent-based mathematical modelling to simulate a biofilm consisting of two competing, distinct types of bacterial populations, each parameterised by their nutrient uptake and aciduricity, periodically subjected to an acid challenge resulting from the metabolism of dietary carbohydrates. (jove.com)
Antimicrobial agents provide a bacterial load reduction and give the commensal bacterial an opportunity to re-establish control of the biofilm. (carifree.com)
In particular, cranberry A-type proanthocyanidins and flavonols have demonstrated potent inhibitory effects against cariogenic virulence targets such as bacterial acidogenicity, aciduricity, glucan synthesis, and hydrophobicity. (cranberryinstitute.org)
Other collaborations, both within and outside the College of Dentistry, foster work to identify novel agents to specifically target cariogenic bacterial species, to coat dental materials with antimicrobials, to examine the microflora associated with localized aggressive periodontitis, and to investigate potential cariogenic properties associated with multiple bacterial species common to dental plaque. (uiowa.edu)
HBM is not cariogenic in an in vitro model, unless another carbohydrate source is available for bacterial fermentation. (dentistryiq.com)
It has both antiseptic and anti-bacterial agents that make it a great warrior against tooth decay. (fogut.com)
With this method, a photosensitizing agent is activated by light at a specific wavelength that corresponds to maximum absorbance by the substance, resulting in the production of free radicals, singlet oxygen, and other reactive oxygen species, which have a toxic effect on bacterial cells, leading to cell death without causing harm to the host [6, 7, 11-13]. (thefreedictionary.com)
RESULTS: In recent years there has been renewed interest in the anticariogenic properties of several natural products, especially those that have the ability to inhibit cariogenic virulence properties or bacterial adhesion without disrupting the key health benefits of the resident oral microbiome. (bvsalud.org)
This study determined the antimicrobial activity of the extracts from F. zanthoxyloides on selected cariogenic and enteric bacterial isolates. (scopemed.org)

Mutanolysin, bacteriolytic agent for cariogenic Streptococci: partial purification and properties. (semanticscholar.org)

Conclusion: These sweeteners along with their low endogenic pH form a high cariogenic formulation. (who.int)

Bioactive polyphenol components of cranberry (Vaccinium macrocarpon) are known to have virulence attenuating effects against several cariogenic virulence properties responsible for dental caries pathogenesis. (cranberryinstitute.org)
Cranberry phenols have the ability to disrupt these cariogenic virulence properties without being bactericidal, a key quality essential for retaining the benefits of the symbiotic resident oral microbiome and preventing the emergence of resistant microbes. (cranberryinstitute.org)

3, 9) This study may prove HBM is cariogenic to rats with no saliva drinking through an artificial nipple, but in no way does this in vitro model mimic a human mother breastfeeding their baby. (dentistryiq.com)

Antimicrobial Agents and Chemotherapy 54(9): 3895-3906. (dal.ca)
Antimicrobial Agents and Chemotherapy 55(11): 5205-5213. (dal.ca)

Dental caries or tooth decay is a prevalent global disease whose causative agent is the oral biofilm known as plaque. (jove.com)
Various non- fluoride agents are also present which helps in prevention of dental caries. (prosestru.cz)
This paper reviews about these non-fluoride agents in the prevention of dental caries. (prosestru.cz)
Various anti plaque agents, and other agents like enzymes have been effectively used as prevention of dental caries. (prosestru.cz)
Since 1970's researches started to search for non-fluoride agents for the prevention of dental caries [ 12 ]. (prosestru.cz)
Non-fluoride agents may serve as adjunctive therapeutics for preventing, arresting or even reversing dental caries. (prosestru.cz)
Varnish application resulted in modification of the dental biofilm toward a less cariogenic one. (bvsalud.org)

The test null hypotheses were that after 14 days of exposure to an intra oral cariogenic environment, the Knoop hardness, μTBS and nanoleakage of resin-dentin interfaces treated by different collagen cross-linking agents did not change. (pocketdentistry.com)

Therefore, the aim of this study was to investigate the degradation of resin-dentin interfaces treated by different collagen cross-linking agents after in situ cariogenic challenge, using microhardness, microtensile bond strength and nanoleakage. (pocketdentistry.com)

3 However, this conventional treatment strategy is not always successful and the addition of chemical agents as an adjunct has been suggested to enhance efficacy in achieving better oral health. (scielo.org.za)

Chlorhexidine has been a standard anti-microbial agent, although it has little effect on Lactobacillus. (carifree.com)
The combination of xylitol/chlorhexidine showed a statistically significant antivital effect on S sanguis cells compared to the pure agents xylitol and chlorhexidine. (quintpub.com)
3 ] Chlorhexidine, triclosan, cetyl pyridinium chloride, essential oils, fluoride based solution are some of the antimicrobial agents tested against oral microbes. (jbclinpharm.org)
7 - 9 ] Chlorhexidine is the gold standard chemical plaque control agent. (jbclinpharm.org)
Chlorhexidine (CHX) is an antimicrobial agent used extensively in dentistry. (bvsalud.org)

The infiltration of these noxious agents at the interface between the material and tooth could pave the way for enhanced degradation of the tooth structure (collagen and mineral) as well as the adhesive polymer. (ku.edu)

The formulations comprise mouthwashes, rinses and dentifrices containing one or more antimicrobial anti-plaque and anti-cariogenic agents. (google.com)

Sorbitol is primarily used as a sweetener, humectant, flavoring agent, and diuretic dehydrating agent for various applications such as food & beverage, pharmaceuticals, and cosmetics & personal care. (marketsandmarkets.com)
It can be used as a bulk sweetener or as a compression agent in sugar-free confectionery (chewing gums, pan coating, tablets), and in biscuits and pastry food applications. (ulprospector.com)

an agent used in photodynamic therapy which, when absorbed by CA cells and exposed to light, is activated, killing cancer cells. (thefreedictionary.com)
In oral antimicrobial photodynamic therapy, toluidine blue and methylene blue photosensitizing agents are the most commonly used [11, 12], since they have a high degree of selectivity for damage for gram-positive and gram-negative bacterias [46-48]. (thefreedictionary.com)

1) It doesn't make sense for a species' specific milk to be cariogenic to its young. (dentistryiq.com)

Xylitol, a 5-carbon naturally occurring sugar alcohol, is a proven anti-caries agent. (carifree.com)
Xylitol has been recognized as an effective anticaries agent and also potentiates the effects of even small amounts of fluoride. (carifree.com)
1, 2 Xylitol is a much less common anticaries agent than fluoride, and in the United States, the FDA only recognizes fluorides as "active ingredients" in anticaries products. (carifree.com)

Analysis of the data suggests that lactose-containing stevioside sweeteners may be cariogenic, especially to dentin. (gu.se)

Further research on anti-cariogenic activity of cocoa, coffee, and tea could open a promising avenue of applications, according to the dentist in Perth, they are relatively safe, have taste and odor largely appreciated and could be used at a reasonable cost in the preparation of specific anti-cariogenic remedies, recommended by Orthodontists Melbourne . (shockmd.com)
5 Chemotherapeutic agents have been used commonly as adjuncts but increasing incidence of failure and the development of resistance to conventional antibiotics has led to the screening of several medicinal plants for their potential antimicrobial activity and host modulating effects. (scielo.org.za)

By using a light source to activate the photosensitizing agent , the targeted approach does not disrupt the surrounding areas. (thefreedictionary.com)

Clove and its derivatives have a definite potential to be used as specific anti-plaque and anti-inflammatory agents for the treatment of periodontal disease. (scielo.org.za)

To evaluate the effect of treatment using collagen cross-linking agents as primer on resin-dentin bond interfaces subjected to cariogenic oral environment (COE). (pocketdentistry.com)
In this context, collagen cross-linking agents have been investigated as dentin biomodifiers. (pocketdentistry.com)

Because of its effectiveness, salt resistance, and minimal toxicity to host cells, this novel target-specific peptide shows promise for future development as an anticaries agent. (asm.org)

These cavities were acid-etched and treated by the primers containing one of the following treatment agents (6.5% proanthocyanidins, 0.1% riboflavin-UVA activated light, 5% glutaraldehyde or distilled water as a control group). (pocketdentistry.com)
It was decided, after further research, that this type of composite could be used for most restorations provided the acid etch technique was used and a bonding agent was applied. (wikipedia.org)

Since 1952, sodium fluoride in toothpaste has been the most widely used therapeutic agent. (oralhealthgroup.com)

Chlorine dioxide is an effective anti-plaque agent, anti-gingivitis and anti-periodontitis agent, and also effective to destroy malodorous sulfur compounds. (google.com)
Anti-plaque agents should not eradicate the oral microbiota. (frontiersin.org)

Anatomy4

Organisms7

Diseases3

Chemicals and Drugs11

Analytical, Diagnostic and Therapeutic Techniques and Equipment10

Psychiatry and Psychology3

Phenomena and Processes4

Disciplines and Occupations3

Anthropology, Education, Sociology and Social Phenomena6

Technology, Industry, Agriculture9

Humanities1

Information Science8

Health Care12

Geographicals1

Food starches and dental caries. (1/43)

Modern methods for assessing the cariogenic and erosive potential of foods. (2/43)

Intake of sweet foods and counts of cariogenic microorganisms in obese and normal-weight women. (3/43)

A mixed-bacteria ecological approach to understanding the role of the oral bacteria in dental caries causation: an alternative to Streptococcus mutans and the specific-plaque hypothesis. (4/43)

Do we need to be concerned about dental caries in the coming millennium? (5/43)

Effect of a Brazilian regional basic diet on the prevalence of caries in rats. (6/43)

Genome sequence of Streptococcus mutans UA159, a cariogenic dental pathogen. (7/43)

Composition of dental plaque formed in the presence of sucrose and after its interruption. (8/43)

Cariogenic Agents

Streptococcus mutans

Diet, Cariogenic

Dental Caries

Saliva

Streptococcal Infections

Click Chemistry

Questionnaires

Bacterial Processes

Allergy and Immunology

Microbiology

Life Tables

Microbiological Techniques

Internet

Fagopyrum

Oral Hygiene

Oral Hygiene Index

Dentifrices

Mouthwashes

Pipidae

Patents as Topic

Hygiene

Peer Group

Video Games

Videotape Recording

Periodicals as Topic

Journal Impact Factor

Peer Review, Research

Peer Review

Chlorine Compounds

Chlorine

Halitosis

Sulfur Compounds

Oxides

Disinfectants

Toothpastes

Wound Healing

Keratinocytes

Fibroblasts

Inventions

Skin

Intellectual Property

Juvenile Delinquency

Ethics, Dental

Health Care Coalitions

Pit and Fissure Sealants

DMF Index

Fluoridation

Chile

Streptococcus sobrinus

Propolis

Cryptocarya

Streptococcus

Actinomyces viscosus

Food starches and dental caries. (1/43)

Modern methods for assessing the cariogenic and erosive potential of foods. (2/43)

Intake of sweet foods and counts of cariogenic microorganisms in obese and normal-weight women. (3/43)

A mixed-bacteria ecological approach to understanding the role of the oral bacteria in dental caries causation: an alternative to Streptococcus mutans and the specific-plaque hypothesis. (4/43)

Do we need to be concerned about dental caries in the coming millennium? (5/43)

Effect of a Brazilian regional basic diet on the prevalence of caries in rats. (6/43)

Genome sequence of Streptococcus mutans UA159, a cariogenic dental pathogen. (7/43)

Composition of dental plaque formed in the presence of sucrose and after its interruption. (8/43)

Computational mechanics in pediatric medicine - University of Strathclyde

New Study: Global Food Starch Market 2018-2025 - Orbis News Release

Biomarkers for Oxidative Stress: Clinical Application in Pediatric Medicine | Bentham Science

Ph Meter, Ph Meter Suppliers and Manufacturers at Alibaba.com

E+h Ph Meter, E+h Ph Meter Suppliers and Manufacturers at Alibaba.com

European Medicines Agency - Paediatric medicines - Paediatric medicines: Workshops

Pediatric Medicine - Everything About Kids & Childrens Health

Pediatric Medicine - Page 3 of 5 - Everything About Kids & Childrens Health

The 2019-2024 Outlook for Pediatric Medicines in China

Working Principle of pH Meter | pH Meter Principle

Wine pH Meter PCE-PH20WINE-ICA incl. ISO Calibration Certificate | PCE Instruments

Wholesale Water Ph Meter, China Wholesale Water Ph Meter Manufacturers & Suppliers | Made-in-China.com

Plaque pH in Caries-Free … - University of Gothenburg, Sweden

Using a pH meter - Stock Image H460/0239 - Science Photo Library

PPT - pH Meter PowerPoint Presentation - ID:4259982

DIY pH Meter & Probe | eHow

Family Medicine | Lowell Community Health Center

Extrapolation in the development of paediatric medicines: examples from approvals for biological treatments for paediatric...