The HEART and the BLOOD VESSELS by which BLOOD is pumped and circulated through the body.
Processes and properties of the CARDIOVASCULAR SYSTEM as a whole or of any of its parts.
Biological actions and events that support the functions of the CARDIOVASCULAR SYSTEM.
Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.
The number of times the HEART VENTRICLES contract per unit of time, usually per minute.
Congenital, inherited, or acquired anomalies of the CARDIOVASCULAR SYSTEM, including the HEART and BLOOD VESSELS.
The hollow, muscular organ that maintains the circulation of the blood.
Theoretical representations that simulate the behavior or activity of the cardiovascular system, processes, or phenomena; includes the use of mathematical equations, computers and other electronic equipment.
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
An inherited disorder of connective tissue with extensive degeneration and calcification of ELASTIC TISSUE primarily in the skin, eye, and vasculature. At least two forms exist, autosomal recessive and autosomal dominant. This disorder is caused by mutations of one of the ATP-BINDING CASSETTE TRANSPORTERS. Patients are predisposed to MYOCARDIAL INFARCTION and GASTROINTESTINAL HEMORRHAGE.
The ENTERIC NERVOUS SYSTEM; PARASYMPATHETIC NERVOUS SYSTEM; and SYMPATHETIC NERVOUS SYSTEM taken together. Generally speaking, the autonomic nervous system regulates the internal environment during both peaceful activity and physical or emotional stress. Autonomic activity is controlled and integrated by the CENTRAL NERVOUS SYSTEM, especially the HYPOTHALAMUS and the SOLITARY NUCLEUS, which receive information relayed from VISCERAL AFFERENTS.
The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.
A vasodilator with general properties similar to NITROGLYCERIN but with a more prolonged duration of action. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1025)
Any of the tubular vessels conveying the blood (arteries, arterioles, capillaries, venules, and veins).
Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components.
The main trunk of the systemic arteries.
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
The biological science concerned with the life-supporting properties, functions, and processes of living organisms or their parts.
The volume of BLOOD passing through the HEART per unit of time. It is usually expressed as liters (volume) per minute so as not to be confused with STROKE VOLUME (volume per beat).
A response by the BARORECEPTORS to increased BLOOD PRESSURE. Increased pressure stretches BLOOD VESSELS which activates the baroreceptors in the vessel walls. The net response of the CENTRAL NERVOUS SYSTEM is a reduction of central sympathetic outflow. This reduces blood pressure both by decreasing peripheral VASCULAR RESISTANCE and by lowering CARDIAC OUTPUT. Because the baroreceptors are tonically active, the baroreflex can compensate rapidly for both increases and decreases in blood pressure.
The nonstriated involuntary muscle tissue of blood vessels.
The vessels carrying blood away from the heart.
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
The neural systems which act on VASCULAR SMOOTH MUSCLE to control blood vessel diameter. The major neural control is through the sympathetic nervous system.
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
An autosomal dominant disorder of CONNECTIVE TISSUE with abnormal features in the heart, the eye, and the skeleton. Cardiovascular manifestations include MITRAL VALVE PROLAPSE, dilation of the AORTA, and aortic dissection. Other features include lens displacement (ectopia lentis), disproportioned long limbs and enlarged DURA MATER (dural ectasia). Marfan syndrome is associated with mutations in the gene encoding fibrillin, a major element of extracellular microfibrils of connective tissue.
Paracrine substances produced by the VASCULAR ENDOTHELIUM with VASCULAR SMOOTH MUSCLE relaxation (VASODILATION) activities. Several factors have been identified, including NITRIC OXIDE and PROSTACYCLIN.
Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
Striated muscle cells found in the heart. They are derived from cardiac myoblasts (MYOBLASTS, CARDIAC).
A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
The thoracolumbar division of the autonomic nervous system. Sympathetic preganglionic fibers originate in neurons of the intermediolateral column of the spinal cord and project to the paravertebral and prevertebral ganglia, which in turn project to target organs. The sympathetic nervous system mediates the body's response to stressful situations, i.e., the fight or flight reactions. It often acts reciprocally to the parasympathetic system.
The force that opposes the flow of BLOOD through a vascular bed. It is equal to the difference in BLOOD PRESSURE across the vascular bed divided by the CARDIAC OUTPUT.
Highly toxic compound which can cause skin irritation and sensitization. It is used in manufacture of azo dyes.
The heart of the fetus of any viviparous animal. It refers to the heart in the postembryonic period and is differentiated from the embryonic heart (HEART/embryology) only on the basis of time.
A colorless, flammable, poisonous liquid, CS2. It is used as a solvent, and is a counterirritant and has local anesthetic properties but is not used as such. It is highly toxic with pronounced CNS, hematologic, and dermatologic effects.
An NADPH-dependent enzyme that catalyzes the conversion of L-ARGININE and OXYGEN to produce CITRULLINE and NITRIC OXIDE.
Agents that affect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume.
Highly specialized EPITHELIAL CELLS that line the HEART; BLOOD VESSELS; and lymph vessels, forming the ENDOTHELIUM. They are polygonal in shape and joined together by TIGHT JUNCTIONS. The tight junctions allow for variable permeability to specific macromolecules that are transported across the endothelial layer.
The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
Elements of limited time intervals, contributing to particular results or situations.
The relationship between the dose of an administered drug and the response of the organism to the drug.
Pathological conditions involving the HEART including its structural and functional abnormalities.
A BLOOD PRESSURE regulating system of interacting components that include RENIN; ANGIOTENSINOGEN; ANGIOTENSIN CONVERTING ENZYME; ANGIOTENSIN I; ANGIOTENSIN II; and angiotensinase. Renin, an enzyme produced in the kidney, acts on angiotensinogen, an alpha-2 globulin produced by the liver, forming ANGIOTENSIN I. Angiotensin-converting enzyme, contained in the lung, acts on angiotensin I in the plasma converting it to ANGIOTENSIN II, an extremely powerful vasoconstrictor. Angiotensin II causes contraction of the arteriolar and renal VASCULAR SMOOTH MUSCLE, leading to retention of salt and water in the KIDNEY and increased arterial blood pressure. In addition, angiotensin II stimulates the release of ALDOSTERONE from the ADRENAL CORTEX, which in turn also increases salt and water retention in the kidney. Angiotensin-converting enzyme also breaks down BRADYKININ, a powerful vasodilator and component of the KALLIKREIN-KININ SYSTEM.
The flow of BLOOD through or around an organ or region of the body.
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
A disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. Indicators of oxidative stress include damaged DNA bases, protein oxidation products, and lipid peroxidation products (Sies, Oxidative Stress, 1991, pxv-xvi).
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
The movement of the BLOOD as it is pumped through the CARDIOVASCULAR SYSTEM.
The portion of the descending aorta proceeding from the arch of the aorta and extending to the DIAPHRAGM, eventually connecting to the ABDOMINAL AORTA.
The lower right and left chambers of the heart. The right ventricle pumps venous BLOOD into the LUNGS and the left ventricle pumps oxygenated blood into the systemic arterial circulation.
Time period from 1501 through 1600 of the common era.
A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
A CALCIUM-dependent, constitutively-expressed form of nitric oxide synthase found primarily in ENDOTHELIAL CELLS.
A multifunctional pyridoxal phosphate enzyme. In the final step in the biosynthesis of cysteine it catalyzes the cleavage of cystathionine to yield cysteine, ammonia, and 2-ketobutyrate. EC 4.4.1.1.
Contractile activity of the MYOCARDIUM.
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.
A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.
Drugs used to cause dilation of the blood vessels.
Forced expiratory effort against a closed GLOTTIS.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
The physiological widening of BLOOD VESSELS by relaxing the underlying VASCULAR SMOOTH MUSCLE.
Receptors in the vascular system, particularly the aorta and carotid sinus, which are sensitive to stretch of the vessel walls.
Distensibility measure of a chamber such as the lungs (LUNG COMPLIANCE) or bladder. Compliance is expressed as a change in volume per unit change in pressure.
Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
The veins and arteries of the HEART.
An involuntary movement or exercise of function in a part, excited in response to a stimulus applied to the periphery and transmitted to the brain or spinal cord.
The physiological narrowing of BLOOD VESSELS by contraction of the VASCULAR SMOOTH MUSCLE.
Teleost hormones. A family of small peptides isolated from urophyses of bony fishes. They have many different physiological effects, including long-lasting hypotensive activity and have been proposed as antihypertensives. There are at least four different compounds: urotensin I, urotensin II, urotensin III, and urotensin IV.
An octapeptide that is a potent but labile vasoconstrictor. It is produced from angiotensin I after the removal of two amino acids at the C-terminal by ANGIOTENSIN CONVERTING ENZYME. The amino acid in position 5 varies in different species. To block VASOCONSTRICTION and HYPERTENSION effect of angiotensin II, patients are often treated with ACE INHIBITORS or with ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS.
A purely physical condition which exists within any material because of strain or deformation by external forces or by non-uniform thermal expansion; expressed quantitatively in units of force per unit area.
A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.
The largest family of cell surface receptors involved in SIGNAL TRANSDUCTION. They share a common structure and signal through HETEROTRIMERIC G-PROTEINS.
Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.
Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.
The development of new BLOOD VESSELS during the restoration of BLOOD CIRCULATION during the healing process.
Non-human animals, selected because of specific characteristics, for use in experimental research, teaching, or testing.
A large class of organic compounds having more than one PHENOL group.
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.
Fermented juice of fresh grapes or of other fruit or plant products used as a beverage.
Peptides that regulate the WATER-ELECTROLYTE BALANCE in the body, also known as natriuretic peptide hormones. Several have been sequenced (ATRIAL NATRIURETIC FACTOR; BRAIN NATRIURETIC PEPTIDE; C-TYPE NATRIURETIC PEPTIDE).
The study of the heart, its physiology, and its functions.
Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.
Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.
Non-striated, elongated, spindle-shaped cells found lining the digestive tract, uterus, and blood vessels. They are derived from specialized myoblasts (MYOBLASTS, SMOOTH MUSCLE).
Cytoplasmic proteins that specifically bind MINERALOCORTICOIDS and mediate their cellular effects. The receptor with its bound ligand acts in the nucleus to induce transcription of specific segments of DNA.
A strain of Rattus norvegicus with elevated blood pressure used as a model for studying hypertension and stroke.
The hemodynamic and electrophysiological action of the HEART VENTRICLES.
Neuropeptides of about 40 amino acids which are structurally similar to CORTICOTROPIN-RELEASING FACTOR. Unlike CRF acting primarily through type 1 CRF RECEPTORS, urocortins signal preferentially through type 2 CRF receptors. Urocortins have wide tissue distribution from fish to mammals, and diverse functions. In mammals, urocortins can suppress food intake, delays gastric emptying, and decreases heat-induced edema.
Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.
A potent natriuretic and vasodilatory peptide or mixture of different-sized low molecular weight PEPTIDES derived from a common precursor and secreted mainly by the HEART ATRIUM. All these peptides share a sequence of about 20 AMINO ACIDS.
Diseases of the parasympathetic or sympathetic divisions of the AUTONOMIC NERVOUS SYSTEM; which has components located in the CENTRAL NERVOUS SYSTEM and PERIPHERAL NERVOUS SYSTEM. Autonomic dysfunction may be associated with HYPOTHALAMIC DISEASES; BRAIN STEM disorders; SPINAL CORD DISEASES; and PERIPHERAL NERVOUS SYSTEM DISEASES. Manifestations include impairments of vegetative functions including the maintenance of BLOOD PRESSURE; HEART RATE; pupil function; SWEATING; REPRODUCTIVE AND URINARY PHYSIOLOGY; and DIGESTION.
The blood pressure in the ARTERIES. It is commonly measured with a SPHYGMOMANOMETER on the upper arm which represents the arterial pressure in the BRACHIAL ARTERY.
Rhythmic, intermittent propagation of a fluid through a BLOOD VESSEL or piping system, in contrast to constant, smooth propagation, which produces laminar flow.
Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.
Any operation on the spinal cord. (Stedman, 26th ed)
Deficient oxygenation of FETAL BLOOD.
A 52-amino acid peptide with multi-functions. It was originally isolated from PHEOCHROMOCYTOMA and ADRENAL MEDULLA but is widely distributed throughout the body including lung and kidney tissues. Besides controlling fluid-electrolyte homeostasis, adrenomedullin is a potent vasodilator and can inhibit pituitary ACTH secretion.
A fetal blood vessel connecting the pulmonary artery with the descending aorta.
The non-genetic biological changes of an organism in response to challenges in its ENVIRONMENT.
The act of breathing with the LUNGS, consisting of INHALATION, or the taking into the lungs of the ambient air, and of EXHALATION, or the expelling of the modified air which contains more CARBON DIOXIDE than the air taken in (Blakiston's Gould Medical Dictionary, 4th ed.). This does not include tissue respiration (= OXYGEN CONSUMPTION) or cell respiration (= CELL RESPIRATION).
The deformation and flow behavior of BLOOD and its elements i.e., PLASMA; ERYTHROCYTES; WHITE BLOOD CELLS; and BLOOD PLATELETS.
A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
Characteristic properties and processes of the NERVOUS SYSTEM as a whole or with reference to the peripheral or the CENTRAL NERVOUS SYSTEM.
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
Physiological processes and properties of the RESPIRATORY SYSTEM as a whole or of any of its parts.
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
Either of the two principal arteries on both sides of the neck that supply blood to the head and neck; each divides into two branches, the internal carotid artery and the external carotid artery.
Transmission of the readings of instruments to a remote location by means of wires, radio waves, or other means. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
The hemodynamic and electrophysiological action of the left HEART VENTRICLE. Its measurement is an important aspect of the clinical evaluation of patients with heart disease to determine the effects of the disease on cardiac performance.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action during the developmental stages of an organism.
A non-selective inhibitor of nitric oxide synthase. It has been used experimentally to induce hypertension.
Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.
Condition under normal Earth gravity where the force of gravity itself is not actually altered but its influence or effect may be modified and studied. (From ASGSB Bull 1992;5(2):27)
Computer-based representation of physical systems and phenomena such as chemical processes.
The main information-processing organs of the nervous system, consisting of the brain, spinal cord, and meninges.
Physical activity which is usually regular and done with the intention of improving or maintaining PHYSICAL FITNESS or HEALTH. Contrast with PHYSICAL EXERTION which is concerned largely with the physiologic and metabolic response to energy expenditure.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
The innermost layer of the heart, comprised of endothelial cells.
The entire nerve apparatus, composed of a central part, the brain and spinal cord, and a peripheral part, the cranial and spinal nerves, autonomic ganglia, and plexuses. (Stedman, 26th ed)
A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (N Eng J Med 1995;333(6):356-63)
Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.
Molecules or ions formed by the incomplete one-electron reduction of oxygen. These reactive oxygen intermediates include SINGLET OXYGEN; SUPEROXIDES; PEROXIDES; HYDROXYL RADICAL; and HYPOCHLOROUS ACID. They contribute to the microbicidal activity of PHAGOCYTES, regulation of signal transduction and gene expression, and the oxidative damage to NUCLEIC ACIDS; PROTEINS; and LIPIDS.
Period of contraction of the HEART, especially of the HEART VENTRICLES.
A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).
Arteries which arise from the abdominal aorta and distribute to most of the intestines.
Guanosine cyclic 3',5'-(hydrogen phosphate). A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed)
An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
The chambers of the heart, to which the BLOOD returns from the circulation.
Particles of any solid substance, generally under 30 microns in size, often noted as PM30. There is special concern with PM1 which can get down to PULMONARY ALVEOLI and induce MACROPHAGE ACTIVATION and PHAGOCYTOSIS leading to FOREIGN BODY REACTION and LUNG DISEASES.
A family of neutral serine proteases with CHYMOTRYPSIN-like activity. Chymases are primarily found in the SECRETORY GRANULES of MAST CELLS and are released during mast cell degranulation.
The heart rate of the FETUS. The normal range at term is between 120 and 160 beats per minute.
A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from PROSTAGLANDIN ENDOPEROXIDES in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension (HYPERTENSION, PULMONARY).
Compounds that suppress the degradation of INCRETINS by blocking the action of DIPEPTIDYL-PEPTIDASE IV. This helps to correct the defective INSULIN and GLUCAGON secretion characteristic of TYPE 2 DIABETES MELLITUS by stimulating insulin secretion and suppressing glucagon release.
Confinement of an individual to bed for therapeutic or experimental reasons.
Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body.
Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
A strain of Rattus norvegicus used as a normotensive control for the spontaneous hypertensive rats (SHR).
The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.
Morphological and physiological development of EMBRYOS or FETUSES.
Arteries originating from the subclavian or axillary arteries and distributing to the anterior thoracic wall, mediastinal structures, diaphragm, pectoral muscles and mammary gland.
The pressure within a CARDIAC VENTRICLE. Ventricular pressure waveforms can be measured in the beating heart by catheterization or estimated using imaging techniques (e.g., DOPPLER ECHOCARDIOGRAPHY). The information is useful in evaluating the function of the MYOCARDIUM; CARDIAC VALVES; and PERICARDIUM, particularly with simultaneous measurement of other (e.g., aortic or atrial) pressures.
Expenditure of energy during PHYSICAL ACTIVITY. Intensity of exertion may be measured by rate of OXYGEN CONSUMPTION; HEAT produced, or HEART RATE. Perceived exertion, a psychological measure of exertion, is included.
Volume of circulating BLOOD. It is the sum of the PLASMA VOLUME and ERYTHROCYTE VOLUME.
The rhythmical expansion and contraction of an ARTERY produced by waves of pressure caused by the ejection of BLOOD from the left ventricle of the HEART as it contracts.
An angiotensin receptor subtype that is expressed at high levels in a variety of adult tissues including the CARDIOVASCULAR SYSTEM, the KIDNEY, the ENDOCRINE SYSTEM and the NERVOUS SYSTEM. Activation of the type 1 angiotensin receptor causes VASOCONSTRICTION and sodium retention.
Compounds that interact with ESTROGEN RECEPTORS in target tissues to bring about the effects similar to those of ESTRADIOL. Estrogens stimulate the female reproductive organs, and the development of secondary female SEX CHARACTERISTICS. Estrogenic chemicals include natural, synthetic, steroidal, or non-steroidal compounds.
The vessels carrying blood away from the capillary beds.
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.
Relatively complete absence of oxygen in one or more tissues.
A significant drop in BLOOD PRESSURE after assuming a standing position. Orthostatic hypotension is a finding, and defined as a 20-mm Hg decrease in systolic pressure or a 10-mm Hg decrease in diastolic pressure 3 minutes after the person has risen from supine to standing. Symptoms generally include DIZZINESS, blurred vision, and SYNCOPE.
A decapeptide that is cleaved from precursor angiotensinogen by RENIN. Angiotensin I has limited biological activity. It is converted to angiotensin II, a potent vasoconstrictor, after the removal of two amino acids at the C-terminal by ANGIOTENSIN CONVERTING ENZYME.
The interruption or removal of any part of the vagus (10th cranial) nerve. Vagotomy may be performed for research or for therapeutic purposes.
The age of the conceptus, beginning from the time of FERTILIZATION. In clinical obstetrics, the gestational age is often estimated as the time from the last day of the last MENSTRUATION which is about 2 weeks before OVULATION and fertilization.
A diverse group of agents, with unique chemical structures and biochemical requirements, which generate NITRIC OXIDE. These compounds have been used in the treatment of cardiovascular diseases and the management of acute myocardial infarction, acute and chronic congestive heart failure, and surgical control of blood pressure. (Adv Pharmacol 1995;34:361-81)
The processes whereby the internal environment of an organism tends to remain balanced and stable.
Sense of awareness of self and of the environment.
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
A genus of the subfamily CERCOPITHECINAE, family CERCOPITHECIDAE, consisting of five named species: PAPIO URSINUS (chacma baboon), PAPIO CYNOCEPHALUS (yellow baboon), PAPIO PAPIO (western baboon), PAPIO ANUBIS (or olive baboon), and PAPIO HAMADRYAS (hamadryas baboon). Members of the Papio genus inhabit open woodland, savannahs, grassland, and rocky hill country. Some authors consider MANDRILLUS a subgenus of Papio.
The resection or removal of the nerve to an organ or part. (Dorland, 28th ed)
A broad group of eukaryotic six-transmembrane cation channels that are classified by sequence homology because their functional involvement with SENSATION is varied. They have only weak voltage sensitivity and ion selectivity. They are named after a DROSOPHILA mutant that displayed transient receptor potentials in response to light. A 25-amino-acid motif containing a TRP box (EWKFAR) just C-terminal to S6 is found in TRPC, TRPV and TRPM subgroups. ANKYRIN repeats are found in TRPC, TRPV & TRPN subgroups. Some are functionally associated with TYROSINE KINASE or TYPE C PHOSPHOLIPASES.
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
The use of hormonal agents with estrogen-like activity in postmenopausal or other estrogen-deficient women to alleviate effects of hormone deficiency, such as vasomotor symptoms, DYSPAREUNIA, and progressive development of OSTEOPOROSIS. This may also include the use of progestational agents in combination therapy.
A method of non-invasive, continuous measurement of MICROCIRCULATION. The technique is based on the values of the DOPPLER EFFECT of low-power laser light scattered randomly by static structures and moving tissue particulates.
Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE).
A peptide of 36 or 37 amino acids that is derived from PROGLUCAGON and mainly produced by the INTESTINAL L CELLS. GLP-1(1-37 or 1-36) is further N-terminally truncated resulting in GLP-1(7-37) or GLP-1-(7-36) which can be amidated. These GLP-1 peptides are known to enhance glucose-dependent INSULIN release, suppress GLUCAGON release and gastric emptying, lower BLOOD GLUCOSE, and reduce food intake.
The lower portion of the BRAIN STEM. It is inferior to the PONS and anterior to the CEREBELLUM. Medulla oblongata serves as a relay station between the brain and the spinal cord, and contains centers for regulating respiratory, vasomotor, cardiac, and reflex activities.
Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.
The amount of BLOOD pumped out of the HEART per beat, not to be confused with cardiac output (volume/time). It is calculated as the difference between the end-diastolic volume and the end-systolic volume.
An exotic species of the family CYPRINIDAE, originally from Asia, that has been introduced in North America. They are used in embryological studies and to study the effects of certain chemicals on development.
Any substance in the air which could, if present in high enough concentration, harm humans, animals, vegetation or material. Substances include GASES; PARTICULATE MATTER; and volatile ORGANIC CHEMICALS.
Naturally occurring or synthetic substances that inhibit or retard the oxidation of a substance to which it is added. They counteract the harmful and damaging effects of oxidation in animal tissues.
The geometric and structural changes that the HEART VENTRICLES undergo, usually following MYOCARDIAL INFARCTION. It comprises expansion of the infarct and dilatation of the healthy ventricle segments. While most prevalent in the left ventricle, it can also occur in the right ventricle.
An alkaloid, originally from Atropa belladonna, but found in other plants, mainly SOLANACEAE. Hyoscyamine is the 3(S)-endo isomer of atropine.
Heteromultimers of Kir6 channels (the pore portion) and sulfonylurea receptor (the regulatory portion) which affect function of the HEART; PANCREATIC BETA CELLS; and KIDNEY COLLECTING DUCTS. KATP channel blockers include GLIBENCLAMIDE and mitiglinide whereas openers include CROMAKALIM and minoxidil sulfate.
Post-systolic relaxation of the HEART, especially the HEART VENTRICLES.
The integration of exogenous DNA into the genome of an organism at sites where its expression can be suitably controlled. This integration occurs as a result of homologous recombination.
A technique that localizes specific nucleic acid sequences within intact chromosomes, eukaryotic cells, or bacterial cells through the use of specific nucleic acid-labeled probes.
Benzene derivatives that include one or more hydroxyl groups attached to the ring structure.
The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.
Drugs used to cause constriction of the blood vessels.
The unborn young of a viviparous mammal, in the postembryonic period, after the major structures have been outlined. In humans, the unborn young from the end of the eighth week after CONCEPTION until BIRTH, as distinguished from the earlier EMBRYO, MAMMALIAN.
The measurement of an organ in volume, mass, or heaviness.
An alpha-1 adrenergic agonist used as a mydriatic, nasal decongestant, and cardiotonic agent.
The active sympathomimetic hormone from the ADRENAL MEDULLA. It stimulates both the alpha- and beta- adrenergic systems, causes systemic VASOCONSTRICTION and gastrointestinal relaxation, stimulates the HEART, and dilates BRONCHI and cerebral vessels. It is used in ASTHMA and CARDIAC FAILURE and to delay absorption of local ANESTHETICS.

Distinct and combined vascular effects of ACE blockade and HMG-CoA reductase inhibition in hypertensive subjects. (1/2013)

Hypercholesterolemia and hypertension are frequently associated with elevated sympathetic activity. Both are independent cardiovascular risk factors and both affect endothelium-mediated vasodilation. To identify the effects of cholesterol-lowering and antihypertensive treatments on vascular reactivity and vasodilative capacity, we studied 30 hypercholesterolemic hypertensive subjects. They received placebo for 4 weeks, either enalapril or simvastatin for 14 weeks, and, finally, both medications for an additional 14 weeks. Postischemic forearm blood flow (MFBF) and minimal vascular resistance (mFVR) were used as indices of vasodilative capacity and structural vascular damage, respectively. Total (resting-stress-recovery phases) cardiovascular (blood pressure [BP] and heart rate [HR]) and regional hemodynamic (FBF and FVR) reactivity to stressful stimuli were calculated as area-under-the-curve (auc) (valuextime). Compared with baseline levels, simvastatin reduced total (TOT-C) and LDL cholesterol (LDL-C) (1.27 mmol/L, P<0.001 and 1.33 mmol/L, P<0.001, respectively). Enalapril also reduced TOT-C and LDL-C (0.6 mmol/L, P<0.001 and 0.58 mmol/L, P<0.05, respectively). MFBF was increased substantially by both treatments (P<0.001). Enalapril had a greater effect (-1.7 arbitrary units (AU), P<0.001) than simvastatin (-0.6 AU, P<0.05) on mFVR. During stress, FBF increased more with enalapril (4.4 FBFxminutes, P<0.001) than with simvastatin (1.8 FBFxminutes, P<0.01). Conversely, FVR stress response was reduced more with enalapril (9.1 FVRxminutes, P<0.001) than with simvastatin (2.9 FVRxminutes, P<0.01). During combination treatment, a significant (0.001>P<0.05) additive effect on hypercholesterolemia, structural vascular damage, BP, and FVR was shown. The findings suggest that angiotensin-converting enzyme (ACE) inhibition induces a larger reduction than HMG-CoA reductase blockade in vascular reactivity and structural damage in hypercholesterolemic hypertensive subjects.  (+info)

Cardiovascular and neuronal responses to head stimulation reflect central sensitization and cutaneous allodynia in a rat model of migraine. (2/2013)

Reduction of the threshold of cardiovascular and neuronal responses to facial and intracranial stimulation reflects central sensitization and cutaneous allodynia in a rat model of migraine. Current theories propose that migraine pain is caused by chemical activation of meningeal perivascular fibers. We previously found that chemical irritation of the dura causes trigeminovascular fibers innervating the dura and central trigeminal neurons receiving convergent input from the dura and skin to respond to low-intensity mechanical and thermal stimuli that previously induced minimal or no responses. One conclusion of these studies was that when low- and high-intensity stimuli induce responses of similar magnitude in nociceptive neurons, low-intensity stimuli must be as painful as the high-intensity stimuli. The present study investigates in anesthetized rats the significance of the changes in the responses of central trigeminal neurons (i.e., in nucleus caudalis) by correlating them with the occurrence and type of the simultaneously recorded cardiovascular responses. Before chemical stimulation of the dura, simultaneous increases in neuronal firing rates and blood pressure were induced by dural indentation with forces >/= 2.35 g and by noxious cutaneous stimuli such as pinching the skin and warming > 46 degrees C. After chemical stimulation, similar neuronal responses and blood pressure increases were evoked by much smaller forces for dural indentation and by innocuous cutaneous stimuli such as brushing the skin and warming it to >/= 43 degrees C. The onsets of neuronal responses preceded the onsets of depressor responses by 1.7 s and pressor responses by 4.0 s. The duration of neuronal responses was 15 s, whereas the duration of depressor responses was shorter (5.8 s) and pressor responses longer (22.7 s) than the neuronal responses. We conclude that the facilitated cardiovascular and central trigeminal neuronal responses to innocuous stimulation of the skin indicate that when dural stimulation induces central sensitization, innocuous stimuli are as nociceptive as noxious stimuli had been before dural stimulation and that a similar process might occur during the development of cutaneous allodynia during migraine.  (+info)

2,3,7,8-Tetrachlorodibenzo-p-dioxin alters cardiovascular and craniofacial development and function in sac fry of rainbow trout (Oncorhynchus mykiss). (3/2013)

Hallmark signs of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) toxicity in rainbow trout sac fry, are yolk sac edema, hemorrhage, craniofacial malformation, and growth retardation culminating in mortality. Our objective was to determine the role of cardiovascular dysfunction in the development of this toxicity. An embryotoxic TCDD dose (385 pg/g egg) caused a progressive reduction in blood flow in rainbow trout sac fry manifested first and most dramatically in the 1st and 2nd branchial arches and vessels perfusing the lower jaw. Blood flow was reduced later in the infraorbital artery and occipital vein of the head as well as segmental vessels and caudal vein of the trunk. Reduced perfusion occurred last in gill branchial arteries involved with oxygen uptake and the subintestinal vein and vitelline vein involved with nutrient uptake. Although heart rate throughout sac fry development was not affected, heart size at 50 days post-fertilization (dpf) was reduced far more than body weight or length, suggesting that the progressive circulatory failure caused by TCDD is associated with reduced cardiac output. Craniofacial development was arrested near hatch, giving rise to craniofacial malformations in which the jaws and anterior nasal structures were underdeveloped. Unlike the medaka embryo, in which TCDD causes apoptosis in the medial yolk vein, endothelial cell death was not observed in rainbow trout sac fry. These findings suggest a primary role for arrested heart development and reduced perfusion of tissues with blood in the early-life stage toxicity of TCDD in trout.  (+info)

Sex, age, cardiovascular risk factors, and coronary heart disease: a prospective follow-up study of 14 786 middle-aged men and women in Finland. (4/2013)

BACKGROUND: Coronary heart disease (CHD) is markedly more common in men than in women. In both sexes, CHD risk increases with age, but the increase is sharper in women. We analyzed the extent to which major cardiovascular risk factors can explain the sex difference and the age-related increase in CHD risk. METHODS AND RESULTS: The study cohort consists of 14 786 Finnish men and women 25 to 64 years old at baseline. The following cardiovascular risk factors were determined: smoking, serum total cholesterol, HDL cholesterol, blood pressure, body mass index, and diabetes. Risk factor measurements were done in 1982 or 1987, and the cohorts were followed up until the end of 1994. The Cox proportional hazards model was used to assess the relation between risk factors and CHD risk. CHD incidence in men compared with women was approximately 3 times higher and mortality was approximately 5 times higher. Most of the risk factors were more favorable in women, but the sex difference in risk factor levels diminished with increasing age. Differences in risk factors between sexes, particularly in HDL cholesterol and smoking, explained nearly half of the difference in CHD risk between men and women. Differences in serum total cholesterol level, blood pressure, body mass index, and diabetes prevalence explained about one-third of the age-related increase in CHD risk among men and 50% to 60% among women. CONCLUSIONS: Differences in major cardiovascular risk factors explained a substantial part of the sex difference in CHD risk. An increase in risk factor levels was associated with the age-related increase in CHD incidence and mortality in both sexes but to a larger extent in women.  (+info)

Cardiovascular, endocrine, and renal effects of urodilatin in normal humans. (5/2013)

Effects of urodilatin (5, 10, 20, and 40 ng. kg-1. min-1) infused over 2 h on separate study days were studied in eight normal subjects with use of a randomized, double-blind protocol. All doses decreased renal plasma flow (hippurate clearance, 13-37%) and increased fractional Li+ clearance (7-22%) and urinary Na+ excretion (by 30, 76, 136, and 99% at 5, 10, 20, and 40 ng. kg-1. min-1, respectively). Glomerular filtration rate did not increase significantly with any dose. The two lowest doses decreased cardiac output (7 and 16%) and stroke volume (10 and 20%) without changing mean arterial blood pressure and heart rate. The two highest doses elicited larger decreases in stroke volume (17 and 21%) but also decreased blood pressure (6 and 14%) and increased heart rate (15 and 38%), such that cardiac output remained unchanged. Hematocrit and plasma protein concentration increased with the three highest doses. The renin-angiotensin-aldosterone system was inhibited by the three lowest doses but activated by the hypotensive dose of 40 ng. kg-1. min-1. Plasma vasopressin increased by factors of up to 5 during infusion of the three highest doses. Atrial natriuretic peptide immunoreactivity (including urodilatin) and plasma cGMP increased dose dependently. The urinary excretion rate of albumin was elevated up to 15-fold (37 +/- 17 micrograms/min). Use of a newly developed assay revealed that baseline urinary urodilatin excretion rate was low (<10 pg/min) and that fractional excretion of urodilatin remained below 0.1%. The results indicate that even moderately natriuretic doses of urodilatin exert protracted effects on systemic hemodynamic, endocrine, and renal functions, including decreases in cardiac output and renal blood flow, without changes in arterial pressure or glomerular filtration rate, and that filtered urodilatin is almost completely removed by the renal tubules.  (+info)

System identification of closed-loop cardiovascular control mechanisms: diabetic autonomic neuropathy. (6/2013)

We applied cardiovascular system identification (CSI) to characterize closed-loop cardiovascular regulation in patients with diabetic autonomic neuropathy (DAN). The CSI method quantitatively analyzes beat-to-beat fluctuations in noninvasively measured heart rate, arterial blood pressure (ABP), and instantaneous lung volume (ILV) to characterize four physiological coupling mechanisms, two of which are autonomically mediated (the heart rate baroreflex and the coupling of respiration, measured in terms of ILV, to heart rate) and two of which are mechanically mediated (the coupling of ventricular contraction to the generation of the ABP wavelet and the coupling of respiration to ABP). We studied 37 control and 60 diabetic subjects who were classified as having minimal, moderate, or severe DAN on the basis of standard autonomic tests. The autonomically mediated couplings progressively decreased with increasing severity of DAN, whereas the mechanically mediated couplings were essentially unchanged. CSI identified differences between the minimal DAN and control groups, which were indistinguishable based on the standard autonomic tests. CSI may provide a powerful tool for assessing DAN.  (+info)

Considerations in pharmaceutical conversion: focus on antihistamines. (7/2013)

The practice of pharmaceutical conversion, which encompasses three types of drug interchange (generic, brand, and therapeutic substitution), is increasing in managed care settings. Pharmaceutical conversion has numerous implications for managed care organizations, their healthcare providers, and their customers. Although drug cost may be a driving consideration in pharmaceutical conversion, a number of other considerations are of equal or greater importance in the decision-making process may affect the overall cost of patient care. Among these considerations are clinical, psychosocial, and safety issues; patient adherence; patient satisfaction; and legal implications of pharmaceutical conversion. Patient-centered care must always remain central to decisions about pharmaceutical conversion. This article discusses the issues related to, and implications of, pharmaceutical conversion utilizing the antihistamines class of drugs as the case situation.  (+info)

Connexin 43 expression reflects neural crest patterns during cardiovascular development. (8/2013)

We used transgenic mice in which the promoter sequence for connexin 43 linked to a lacZ reporter was expressed in neural crest but not myocardial cells to document the pattern of cardiac neural crest cells in the caudal pharyngeal arches and cardiac outflow tract. Expression of lacZ was strikingly similar to that of cardiac neural crest cells in quail-chick chimeras. By using this transgenic mouse line to compare cardiac neural crest involvement in cardiac outflow septation and aortic arch artery development in mouse and chick, we were able to note differences and similarities in their cardiovascular development. Similar to neural crest cells in the chick, lacZ-positive cells formed a sheath around the persisting aortic arch arteries, comprised the aorticopulmonary septation complex, were located at the site of final fusion of the conal cushions, and populated the cardiac ganglia. In quail-chick chimeras generated for this study, neural crest cells entered the outflow tract by two pathways, submyocardially and subendocardially. In the mouse only the subendocardial population of lacZ-positive cells could be seen as the cells entered the outflow tract. In addition lacZ-positive cells completely surrounded the aortic sac prior to septation, while in the chick, neural crest cells were scattered around the aortic sac with the bulk of cells distributed in the bridging portion of the aorticopulmonary septation complex. In the chick, submyocardial populations of neural crest cells assembled on opposite sides of the aortic sac and entered the conotruncal ridges. Even though the aortic sac in the mouse was initially surrounded by lacZ-positive cells, the two outflow vessels that resulted from its septation showed differential lacZ expression. The ascending aorta was invested by lacZ-positive cells while the pulmonary trunk was devoid of lacZ staining. In the chick, both of these vessels were invested by neural crest cells, but the cells arrived secondarily by displacement from the aortic arch arteries during vessel elongation. This may indicate a difference in derivation of the pulmonary trunk in the mouse or a difference in distribution of cardiac neural crest cells. An independent mouse neural crest marker is needed to confirm whether the differences are indeed due to species differences in cardiovascular and/or neural crest development. Nevertheless, with the differences noted, we believe that this mouse model faithfully represents the location of cardiac neural crest cells. The similarities in location of lacZ-expressing cells in the mouse to that of cardiac neural crest cells in the chick suggest that this mouse is a good model for studying mammalian cardiac neural crest and that the mammalian cardiac neural crest performs functions similar to those shown for chick.  (+info)

CHSS 2019 Abstracts: Pulsatile Perfusion Of Cardiovascular Progenitor Cells Drives Vascular Smooth Muscle Differentiation And A Contractile Phenotype
Consumption of carbohydrates has been demonstrated to alter resting cardiovascular function and cardiovascular reactions to mental stress (known as cardiovascular reactivity). Previous investigations of the effects of acute carbohydrate administration on cardiovascular reactivity suggest that ingestion of glucose followed by mental stress alters hemodynamic responses by attenuating elevations in cardiac output and increasing total peripheral resistance. However, these prior investigations have utilized tasks which have limited generalizability to real-life stressors and were conducted with participants in a recumbent position. The present study investigated the effects of oral glucose administration on resting cardiovascular parameters and cardiovascular reactivity in twenty four seated healthy male college students. Interpersonal speech and anger recall tasks were utilized to elicit a greater emotional response than those used in previous studies and to more closely mirror stressors encountered ...
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Research in Cardiovascular Biology at UVA focuses on mechanisms that contribute to major cardiovascular diseases such as atherosclerosis, aneurysms, hypertension, peripheral vascular disease, heart failure, myocardial infarction, and stroke.Over 150 former trainees now hold leadership positions in academia, industry, and other biomedical science-related disciplines. Students perform research in one of the many laboratories housed in our world-renowned Robert M. Berne Cardiovascular Research Center (CVRC). Training is augmented through our NIH-funded Cardiovascular Research Training Program, which prepares students for highly successful biomedical research careers in a broad range of areas, including studies of basic cardiovascular development and function. Our research also focuses on the development of novel drugs, devices, diagnostic methods, imaging modalities, and other therapeutic approaches to better diagnose, prevent, or treat cardiovascular disease.. ...
Cardiovascular System - Cardiovascular System Diagram - Cardiovascular System Chart - Cardiovascular Diagram - Cardiovascular system is a visual representation of the human organs carrying blood through the body including human heart, veins, arteries and aorta.
There are several possible explanations for the dominant effect of age on the likelihood for occurrence of these cardiovascular diseases. One is that aging is synonymous with disease; however, many people achieve old age without evidence of these diseases. Another explanation for the epidemic of cardiovascular disease in older persons is that other defined risk factors co-vary in number or severity with increasing age. A related, but distinct, idea is that increasing age contributes to an increased exposure time to these other age-dependent risk factors. According to this view, time indirectly confers an increased risk for the occurrence and increased severity and extent of pathophysiological manifestations of these diseases in older persons. A somewhat different view is that cardiovascular structure and function change with time because an aging process, and that, over time, this process alters the substrate on which specific pathophysiological disease mechanisms, such as those that have ...
VÁLYI Péter. [The world population in both industrialized and developing countries is aging. The clinical and economic implications of this demographic shift are staggering because age is the most powerful risk factor for cardiovascular diseases. The incidence and prevalence of hypertension, coronary artery disease, congestive heart failure, and stroke increase steeply with advancing age. Although epidemiologic studies have discovered that some aspects of lifestyle and genetics are risk factors for these diseases, age, per se, confers the major risk. There is a continuum of age-related alterations of cardiovascular structure and function in healthy humans, however these alterations are not synonymous with diseases processes. Old age is not a disease. Although cardiovascular aging changes are considered normative, they lower the threshold for development of cardiovascular disease, and appear to influence the steep increases in hypertension, atherosclerosis, stroke, left ventricular ...
The cardiovascular structures are normal in size. No abnormalities are noted in the pulmonary parenchyma, mediastinum, or pleural space. There is lysis of the spinous process of the second thoracic vertebra. Spine technique radiographs were requested, confirming the finding from the thoracic series. A pathologic fracture is visible on the additional images ...
Study Flashcards On OCR GCSE PE at Cram.com. of exercise on the cardiovascular system. long term effects on the respiratory system and what are the.O2 is carried via circulatory system around the body in the red blood cells.Cardiovascular System. excessive alcohol can have harmful effects on the cardiovascular system.Find PowerPoint Presentations and Slides using the power of.. The Effect of Diet on the Circulatory System. Your diet has a significant effect upon the overall health and.Your diet and exercise level can have a substantial effect on your skeletal system.High-altitude training exerts beneficial effects on your respiratory system. This is done by converting nutrients from your diet to ...
BOSTON , MA - By the beginning of this year, a consensus had developed on the link between COX-2 drugs and heart disease risk: The evidence for cardiovascular…
Capecitabine is a chemotherapy drug used to treat many types of cancer including bowel and stomach cancer. Unfortunately a side effect of this drug is t
Materials and Methods: the functional indices of the cardiovascular system of 61 boys aged 10 to 15 years, who were engaged in karate for more than 2 years (the main group) and 50 boys of the same age, not engaged in sports activities (the control group) were studied. The assessment of the cardiovascular system included heart rate (HR), stroke volume (SV) and minute volume (MV) of blood. The indices of cardiovascular system were examined at rest and on the 2nd, 3rd, 4th minute of recovery period after the Harvard step test ...
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The cardiovascular system consists of the heart, blood vessels, and the approximately 5 liters of blood that the blood vessels transport. Responsible for transporting oxygen, nutrients, horm
The Harvard Step Test Procedure to Assess Cardiovascular System. This article will discuss how to assess cardiovascular system capacity? which influence the endurance ability. The objective of this test is to monitor the development of the athletes cardiovascular system ...
Wall Street brokerages expect Cardiovascular Systems Inc (NASDAQ:CSII) to announce earnings per share of ($0.03) for the current quarter, according to Zacks. Four analysts have made estimates for Cardiovascular Systems earnings. The highest EPS estimate is $0.00 and the lowest is ($0.05). Cardiovascular Systems reported earnings per share of $0.01 during the same quarter last […]
Cardiologists and oncologists must work together in an attempt to avoid or prevent adverse cardiovascular effects in patients from certain chemotherapies, especially for those who may be at a higher risk for such effects, according to a new review published online December 10 in the Journal of the National Cancer Institute.. With an aging population, it is highly probable that an increasing number of people may have both cancer and cardiovascular disease. Many chemotherapeutic and chemoprevention drugs affect the cardiovascular system, making cardiovascular side effects a new challenge in cancer therapy.. In a review of the literature, Adriana Albini, Ph.D., Chief of Oncology Research of the Clinical and Research Institute MultiMedica, Milan, Italy, Francesco Donatelli, Chief of MultiMedica Cardiovascular Department, and others from the Universities of Milan, Genova and Varese, summarize the potential cardiovascular toxicities for a range of cancer chemotherapeutic and chemopreventive agents and ...
The circulatory system is a closed system in which the heart consists of two pumps in series. During pulmonary circulation, blood rich in oxygen is pumped into the left atrium of the heart from the lungs, whereas blood low in oxygen exits the heart through the right ventricle to the lung. The main function of the circulatory (or cardiovascular) system is to deliver oxygen to the body tissues, whilst simultaneously removing carbon dioxide produced by metabolism. The blood carries oxygen and nutrients to every cell of the body. The cardiovascular system helps regulate the temperature with the following: Balancing the fluids in the body means that every cell gets the proper amount of electrolytes, nutrients and gases. These are the main roles of the circulatory system. 5. The circulatory system carries oxygen, nutrients, and . It transports oxygen and other essential substances throughout the body, fights sickness, and performs other vital functions. Blood is propelled by the heart, with arteries, ...
Comprehensive Cardiovascular Profile by Genova Diagnostics analyzes blood for levels of HDL, LDL, and total cholesterol, ratios, triglycerides, lipoprotein(a), homocysteine, apolipoprotein A1, apolipoprotein B, fibrinogen, and C-reactive protein. Buy Comprehensive Cardiovascular Profile online with free shipping!
Challenge and threat reflect two distinct psychophysiological approaches to motivated performance situations. Challenge is related to superior performance in a range of tasks compared to threat, thus methods to promote challenge are valuable. In this paper we manipulate challenge and threat cardiovascular reactivity using only resource appraisals, without altering perceived task demands between challenge and threat conditions. Study 1 used a competitive throwing task and Study 2 used a physically demanding climbing task. In both studies challenge task instructions led to challenge cardiovascular reactivity and threat task instructions led to threat cardiovascular reactivity. In Study 1, participants who received challenge instructions performed better than participants who received threat instructions. In Study 2, attendance at the climbing task did not differ across groups. The findings have implications for stress management in terms of focusing on manipulating appraisals of upcoming tasks by ...
Moving blood throughout the body, the circulatory system, also called the cardiovascular system, comprises 4 parts, the heart, arteries, blood, capillaries, and veins. This system stabilizes body temperature and pH, maintains homeostasis, moves nutrients (such as amino acids and electrolytes), oxygen, carbon dioxide, hormones, and blood cells into and out of the cells nourishing and fighting disease, while simultaneously keeping us alive [1-2].. This transport of oxygenated blood from the lungs and heart throughout the body occurs through the arteries. As heart disease remains the number one cause of death, coronary artery disease, heart failure, heart attack, arrhythmia, and other cardiovascular conditions such as hypertension and high blood cholesterol levels can damage the cardiovascular system [3-4].. We often overlook the importance of sufficiently effective blood flow to the brain, when considering the mood and cognitive disorders. In studies, we find an improvement in mood and cognition, ...
Anatomy of the Cardiovascular System. Cardiovascular System. Also circulatory system Consists of: the heart , arteries , veins , capil laries. Heart. Four chamber muscular organ Comparable to the size of a closed fist Located in the mediastinum. Heart. Coverings of the Heart....
Research summary:. Lipid mediators as prostanoids and cholesterol derivatives play an essential role in inflammatory processes associated to the onset and development of a number of pathologies as cardiovascular diseases. Prostanoids participate in the inflammatory response and exert important actions in the cardiovascular system, modulating vascular homeostasis and participating in the pathogenesis of vascular diseases. Their importance in inflammation and in maintaining cardiovascular homeostasis is highlighted by clinical experience with drugs inhibiting their production as NSAIDs. In spite of their well-known properties as anti-inflammatory drugs, recent studies have shown that cyclooxygenase-2 selective NSAIDs inhibitors increase the risk of adverse cardiovascular side effects. On the other hand, oxysterols and drugs acting as LXR ligands play a central regulatory role in lipid uptake, metabolism and efflux through their properties as transcriptional regulators of gene expression. In ...
Human cardiovascular system - Human cardiovascular system - Electrocardiogram: The electrical impulse that is generated by each depolarization of the heart can be characterized and examined with the use of an electrocardiogram. From a clinical standpoint, the electrocardiogram has become useful as a mechanism of diagnosing cardiac disease. The circuitry of the electrocardiogram allows the detection of small changes in voltage that occur rhythmically with cardiac excitation. It was discovered in the early 20th century that these changes could be evaluated by leads (wires) that were placed on the chest, arms, and legs. Potential differences between different sets of leads are examined throughout the cardiac cycle. Ultimately, the readout
When You Exercise How Does the Cardiovascular System Respond?. During exercise, the job of the cardiovascular system is to deliver blood and oxygen from the heart and lungs to your working muscles. Oxygen is needed for many types of exercise. Your blood carries nutrients to your muscle cells to create energy that your ...
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Natural Nutrition Supplements For Womens Cardiovascular System Health -- The Secrets That Will Provide You Complete Cardiovascular System Health
The Cardiovascular System The cardiovascular system consists of a heart and an enclosed system of blood vessels categories into arteries, capillaries and
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Nutra Q10 For a fit cardiovascular system. Forever Livings Nutra Q10 has been specifically designed to keep the cardiovascular system running smoothly thanks to its unique formula. Nutra Q10 contains coenzyme Q10, as well as vitamins (E, C, B6, B12), magnesium, folic acid
MRI and CT of the Cardiovascular System : MRI and CT of the Cardiovascular System Pub Date: October 2005 Product Type: Print Author/
Need homework help? Answered: Chapter 13: Cardiovascular System. Verified Textbook solutions for problems 1 - 24. The cardiovascular system includes the (p. 341)
Two programs were used to demonstrate the effects of drugs on cardiovascular function. The Virtual Cat and RatCVS software programs developed by the University of Strathclyde, Glasgow, UK offer different platforms for CVS experimentation in whole animal models. The virtual cat can be used to demonstrate the effects of 15 standard drugs and 17 unknown drugs on blood pressure and heart rate, skeletal muscle contractions, and nictitating membrane twitches. Students used this program to investigate the effects of agonists, antagonists, and vasodilators on cardiovascular function. RatCVS simulates pithed and normal rat preparations, which are suitable for demonstrating the effects of drugs on the cardiovascular system without the superimposing effects of central baroreceptor reflexes. Pithing refers to the destruction of the spinal cord and the severance of central innervation to the cardiovascular system. The software gave options of using pithed or normal rat and provided the option of using 22 ...
In the 50s, the development of medical technology has made it possible to conduct laboratory tests to identify certain factors of the human blood. These very tests indicated an increase in cholesterol and triglycerides in the blood of people suffering from cardiovascular pathologies. As required at the time, with primitive thinking, the scientists have hastily deduced a conclusion about the role of identified substances in the occurrence of human cardiovascular pathologies as well as in the resulting heart attacks and strokes. The given theory emerged about 50 years ago, while the drugs against cholesterol and triglycerides - about 30 years ago. According to the rules of logic and science, having eliminated the source of the disease, the disease itself should disappear forever. Nevertheless, nowhere in the world can anyone show a single cardiovascular patient who had recovered from this disease by taking drugs against cholesterol and triglycerides. Whereas based on the proposed theory, we had to ...
http://library.med.utah.edu/WebPath/jpeg5/CV140.jpg The right ventricle and atrium are opened to reveal a pacemaker wire that extends to the apex to embed on the septum. Pacemakers aid in maintaining a rhythm in hearts prone to arrhythmias.
Visit Healthgrades for information on Dr. Gary Fishbein, MD Find Phone & Address information, medical practice history, affiliated hospitals and more.
There is currently a deficiency in understanding the events that effect proper cardiovascular development. The long-term goal is to define these events in molec...
Learn about the veterinary topic of The Cardiovascular System in Animals. Find specific details on this topic and related topics from the Merck Vet Manual.
Questa meta analisi riguarda gli effetti dellesercizio aerobico sulla pressione arteriosa e si basa su ricerche cliniche randomizzate e controllate: abbiamo incluso 54 lavori su 2419 soggetti di un ampio spettro di regioni geografiche e di etnie. Lo studio ha dimostrato che lesercizio fisico ha un impressionante effetto sullabbassamento della pressione arteriosa: mmHg per la sistolica e mmHg per la diastolica. Bisogna distinguere limportanza di questi risultati per i singoli soggetti da quelli sulla salute della popolazione. La riduzione di pressione che abbiamo documentato può essere di scarsa importanza per i medici di singoli pazienti; daltra parte, una piccola riduzione della pressione media in una popolazione può ridurre in maniera eccezionale lincidenza delle malattie cardiovascolari e dei conseguenti decessi in una comunità. Tutti i tipi di esercizio sono efficaci per la riduzione della pressione. Lesercizio aerobico riduce la resistenza allinsulina e i livelli di insulina negli ipertesi.
Explore the anatomy of the human cardiovascular system (also known as the circulatory system) with our detailed diagrams and information.
Background: A tumor cell subset known as stem like cells (SLC) defy conventional therapies, requiring identification of SLC-specific therapeutic targets. We established that elevated COX-2 expression by breast cancer cells promotes tumor progression via inactivation of host immune cells, enhancement of cancer cell migration and invasiveness, and promotion of tumor-associated angiogenesis and lymphangiogenesis primarily by activation of the PGE-2 receptor EP4 on tumor and host cells. Cardiovascular side effects of long term use of COX-2 inhibitors argued for an alternative target, potentially EP4. Objectives/approaches: We asked whether COX-2 or EP4 additionally stimulates SLC in breast cancer. COX-2 and HER-2, often co-expressed in human breast cancer, are both major determinants of cancer progression. To define the roles of COX-2 in HER2 +ve and -ve cells, COX-2 cDNA was stably transfected into COX-2-low, HER-2-ve, ER+ve, non-metastatic MCF-7 and COX-2-ve, ER-ve, HER-2-high SKBR-3 human breast ...
NEJM 8/31 - Results of the VIGOR trial in 2001 shook the medical world with controversy as concern over cardiovascular side effects pushed several COX-2 drugs off the market. Cox-2s were not only interesting for their anti-inflammatory effect, but also due to evidence of protection from colorectal adenomas - the precursor to colorectal cancer. But…
The post Asthma is caused by a response of the: Select one: A. cardiovascular system. B. respiratory system. C. immune system. D. endocrine system. appeared
What is the role of the cardiovascular system?. The cardiovascular system consists of the heart, blood, and blood vessels (veins, arteries, arterioles and capillaries). The cardiovascular system is responsible for circulating blood throughout the body providing oxygenation, homeostasis, regulation, protection and waste removal. Pulmonary circulation carries blood between the heart and lungs while systemic circulation delivers oxygenated blood to the entire body.. How does the cardiovascular system work?. The heart acts as a pumping system that forces blood into the lungs (pulmonary system) and the body (systemic system) so that oxygen, waste removal and regulation all occur. The pump forces blood into the lungs and out into the rest of the system. The arteries deliver oxygenated blood to the body as the pump action of the heart forces the blood into the arterioles and capillaries that are located in our extremities. The veins then return the deoxygenated blood and blood that has picked up waste ...
..MCQ Physiology Cardiovascular System..Cardiac muscle acts as a functional syncytium because it: a. Has larger T-tubules b. Has gap junctions between adjacent
Anatomy and Physiology of the Cardiovascular System. Prepared by Miss Fatima Hirzallah. The heart is a hollow, muscular organ situated in the space between lungs(mediastinum) , its about 12 cm in length & about 9 cm in width. Cardiac Muscle . Contract as a single unit Slideshow...
Learn Inotropes - Pharmacology - Cardiovascular System - NCLEX® - Picmonic for Nursing RN faster and easier with Picmonics unforgettable videos, stories, and quizzes! Picmonic is research proven to increase your memory retention and test scores. Start learning today for free!
Alfonso Caiazzo, Irene Vignon-Clementel. Mathematical Modeling of Blood Flow in the Cardiovascular System. Quantification of Biophysical Parameters in Medical Imaging, Springer International Publishing, pp.45-70, 2018. ⟨hal-01955520⟩ ...
The cardiovascular system (CVS) includes both the heart, i.e. endocardium, myocardium and pericardium, and vessels. Biopsies from these organs are relatively uncommon, and most cases actually originate from autopsies. Disease spectrum ranges from inflammatory, ischaemic and degenerative with a handful of primary and metastatic neoplasms involving the heart. Various distinct types of vasculopathies are also sometimes seen in clinical practice. In this chapter, morphological features on light microscopy and utility of special and immunohistochemical (IHC) stains, which are helpful in the workup of these lesions, are described in a compact fashion.
Students explore the heart and cardiovascular system by dissecting a sheeps heart, creating a model of coronary artery disease and a poster of a heart attack, and learning about signs and symptoms of a heart attack. (3 activities).
Lymperopoulos, A. (2015). The Cardiovascular Adrenergic System. SpringerLink. ISBN 978-3-319-13680-6. Simko, Fedor; Baka, Tomas ... The adrenergic system modulates the fight-or-flight response. Since this response, which is mostly seen as an increase in blood ... There are few non-cardiovascular uses for adrenergic antagonists. Alpha-adrenergic antagonists are also used for treatment of ... John Malcolm Cruickshank (2010). The Modern Role of Beta-Blockers in Cardiovascular Medicine. Shelton, Conn: PMPH-USA. ISBN 978 ...
The Cardiovascular System". Geriatric physical diagnosis: a guide to observation and assessment (illustrated ed.). McFarland. p ... J. Lerman M.D.; J. H. Means M.D. (October 1932). "Cardiovascular symptomatology in exophthalmic goiter". Am Heart J. 8 (1): 55- ...
"The Heart and Cardiovascular System". Cardiovascular Research. 26 (7): 720b. doi:10.1093/cvr/26.7.720b. ISSN 0008-6363. S ... The right heart is a low-pressure system, so the P2 component of the second heart sound is usually softer than the A2 component ... Different forms are associated with cardiovascular disease, connective tissue disorders and hypertension. The symptoms of the ... Klabunde, RE (2009-07-02). "Pressure Gradients". Cardiovascular Physiology Concepts. Richard E. Klabunde. Archived from the ...
Visualization of the cardiovascular system. Replacement of manual dexterity by the "virtual knife" of the automatic sectional ... which visualises the cardiovascular system of the deceased with the aid of a peristaltic pump and contrast medium; Image- and ... Ebert LC, Ptacek W, Naether S, Fürst M, Ross S, Buck U, Weber S, Thali M (2010). "Virtobot--a multi-functional robotic system ... It describes a multi-functional robotic system. The Virtangio machine is a device that is trademarked to Prof. R. Dirnhofer and ...
The cardiovascular system of tunas, as in many fish species, can be described in terms of two RC networks, in which the system ... Brill, Richard W.; Bushnell, Peter G. (2001). The cardiovascular system of tunas. Fish Physiology. 19. pp. 79-120. doi:10.1016/ ... The circulatory system works together with the respiratory system to rapidly transport oxygen to tissues. Due to high ... Instead, the southern bluefin tuna seems to implement a system that regulates how actively the rete mirable system heats the ...
"The Cardiovascular System (Blood Vessels)". www2.highlands.edu. Retrieved 2017-04-22. [email protected] "Printed ...
Unlike the cardiovascular system, the lymphatic system is not closed and has no central pump. Lymph movement occurs despite low ... As part of the lymphatic system, lymph vessels are complementary to the cardiovascular system. Lymph vessels are lined by ... Rosse C, Gaddum-Rosse P (1997). "The Cardiovascular System (Chapter 8)". Hollinshead's Textbook of Anatomy (Fifth ed.). ... A valve system in place here prevents the absorbed lymph from leaking back into the ISF. This valve system involves collagen ...
Adverse cardiovascular effects occur from chronic exposure to noise due to the sympathetic nervous system's inability to ... "Environmental Noise and the Cardiovascular System". Journal of the American College of Cardiology. 71 (6): 688-697. doi:10.1016 ... The sympathetic nervous system maintains lighter stages of sleep when the body is exposed to noise, which does not allow blood ... Exposure to loud noises, either in a single traumatic experience or over time, can damage the auditory system and result in ...
Adams HR (1995). Drugs Acting on the Cardiovascular System. Veterinary Pharmacology and Therapeutics (7th ed.). pp. 451-500. ... It is classified by the Vaughan Williams classification system as class Ia; thus it is a sodium channel blocker of ... 2013). Cardiovascular Therapeutics: A companion to Braunwald's heart disease (4th ed.). Philadelphia, PA: Elsevier/Saunders. p ...
The cardiovascular system must now adapt. The detachment of the placenta causes an increase in systemic vascular resistance, ... All of these cardiovascular system changes result in the adaptation from fetal circulation patterns to an adult circulation ... Pallor and central cyanosis (cyanosis in hands and feet is a common and normal finding) can also indicate cardiovascular issues ... Assessments/Interventions: Assessment and monitoring of vital signs and skin color are important in detecting cardiovascular ...
Pulsus paradoxus Disorders of the Cardiovascular System; Harrison's Principles of Internal Medicine 17th, and Self-assessment ... Board Review cardiovascular system questions 15, 29 Meyer, Theo E.; Sareli, Pinhas; Marcus, Richard H.; Pocock, Wendy; Berk, ... This impaired filling causes the increased blood flow to back up into the venous system, causing the jugular vein distension ( ...
Wang XB, Jin HF, Tang CS, Du JB (16 Nov 2011). "The biological effect of endogenous sulfur dioxide in the cardiovascular system ... CO modulates functions of the cardiovascular system. CO inhibits blood platelet aggregation and adhesion. CO may play a role as ... Tian H. (Nov 2014). "Advances in the study on endogenous sulfur dioxide in the cardiovascular system". Chin Med J. 127 (21): ... carbon monoxide and hydrogen sulphide in the cardiovascular system and in inflammation-a tale of three gases!". Pharmacology & ...
Cardiovascular System Dynamics Society Scharhag, J.ürgen. "Athlete's heart". Athlete's heart. "Cardiovascular Physiology- ... Diseases of the cardiovascular system, such as hypertension and heart failure, are often associated with changes in CO. ... A plot of a system's pressure versus volume has long been used to measure the work done by the system and its efficiency. This ... This could be a normal reversible response to cardiovascular conditioning (athletic heart) or an abnormal irreversible response ...
"Decadal Cycles in the Human Cardiovascular System". World Heart Journal. 4 (4): 263-287. ISSN 1556-4002. PMC 4028693. PMID ...
She has written the book Reactive Oxygen Species and the Cardiovascular System, which describes how various oxygen species can ... Reactive oxygen species and the cardiovascular system. Morgan & Claypool. ISBN 9781615043620. OCLC 777220981. "University of ... affect the way that the cardiovascular system operates. She is a clinician-scientist and her areas of research include clinical ... She is the British Heart Foundation (BHF) Chair of Cardiovascular Medicine and Assistant Director of the ICAMS BHF Award of ...
Peters, S. L.; Alewijnse, A. E. (2007). "Sphingosine-1-phosphate signaling in the cardiovascular system". Current Opinion in ... A general second messenger system mechanism can be broken down into four steps. First, the agonist activates a membrane-bound ... The G-protein coupled receptors for the PIP2 messenger system produces two effectors, phospholipase C (PLC) and ... found primarily in the central nervous system, and the CB2 receptor which is found primarily in lymphocytes and the periphery. ...
It strengthens muscles and improves the cardiovascular system. According to the National Institutes of Health, there are four ... Advances in Intelligent Systems and Computing. 498. doi:10.1007/978-3-319-42070-7. ISBN 978-3-319-42069-1. Shah, Anup (5 ... Applications of the public health system include the areas of maternal and child health, health services administration, ... a major contributor to global ill health is the fact that approximately 1 billion people lack access to health care systems. ...
"Impact of Electronic Cigarettes on the Cardiovascular System". Journal of the American Heart Association. 6 (9): e006353. doi: ... The three categories for the different kinds of pod mods are an open system, a closed system, or those that use both. Pod mods ... These early systems were generally inefficient at delivering nicotine, in part because the particle sizes of the aerosol were ... The origins of a squonk mod bottom-feeding system go as far back as 2009. A member of the E-Cigarette Forum (ECF) named " ...
ISBN 978-0-00-215173-3. "Science Direct: Cardio-vascular system in Ancient Egypt". "Cataract Surgery In Ancient Egypt: Journal ... Irrigation system - From at least Pre-dynastic times, kings of the Dynasty 0 made the world's first organized irrigation system ... Circulatory system - The earliest known writings on the circulatory system are found in the Ebers Papyrus (16th century BCE), ... System of measurement and Metrology - Ancient Egypt was one of the first civilization to have system of measurement. The ...
The heart functions as a pump and acts as a double pump in the cardiovascular system to provide a continuous circulation of ... Cardiovascular System Dynamics Society Betts, J. Gordon (2013). Anatomy & physiology. pp. 787-846. ISBN 1938168135. Retrieved ... The Gross Physiology of the Cardiovascular System (2nd ed., 2012). See "Chapter 1: Normal Physiology." Hall, Arthur C. Guyton, ... as part of the cardiac conduction system. The components of the cardiac conduction system include the atrial and ventricular ...
A variety of topics covering the cardiovascular system. Dr. Pait makes a statement and contestants determine if the statement ...
"The role of epoxyeicosatrienoic acids in the cardiovascular system". British Journal of Clinical Pharmacology. 80 (1): 28-44. ... Bellien, J; Joannides, R (2013). "Epoxyeicosatrienoic acid pathway in human health and diseases". Journal of Cardiovascular ... "Cytochrome P450 Enzymes in the Bioactivation of Polyunsaturated Fatty Acids and Their Role in Cardiovascular Disease". In ... "The pharmacology of the cytochrome P450 epoxygenase/soluble epoxide hydrolase axis in the vasculature and cardiovascular ...
... s have developed a highly functioning cardiovascular system. However, with this development of hugely ...
Veenman L, Gavish M (June 2006). "The peripheral-type benzodiazepine receptor and the cardiovascular system. Implications for ...
Nichols, C. G.; Lederer, W. J. (1991). "Adenosine triphosphate-sensitive potassium channels in the cardiovascular system". The ...
"The Protective Effects of Estrogen on the Cardiovascular System". New England Journal of Medicine. 340 (23): 1801-1811. doi: ... Among postmenopausal women, cardiovascular disease, cancer, and osteoporosis are the leading causes of morbidity and mortality ... Among women in all age groups, cancer and cardiovascular disease are the leading causes of mortality. As the incidence of these ... In 1990, however, interest in the impact of diet on cancer and cardiovascular disease in women was renewed, and a joint ...
Agabegi, Elizabeth D; Agabegi, Steven S. (2008). "Diseases of the Cardiovascular system Section: Valvular Heart Disease". Step- ... The third and current version of this simulator uses a servo motor and a sound card to mimic the cardiovascular functions of ... Older version of Harvey Cardiovascular Patient Simulator Removing panels on sides of older version of Harvey shows internal ... Oddone EZ, Waugh Robert A, Samsa G, Corey R, Feussner JR (October 1993). "Teaching cardiovascular examination skills: results ...
197 citations: A system for real-time XMR guided cardiovascular intervention. Kawal S Rhode, Maxime Sermesant, David Brogan, ... "A system for real-time XMR guided cardiovascular intervention". IEEE Transactions on Medical Imaging. 24 (11): 1428-1440. doi: ... JACC: Cardiovascular Imaging 6 (4), 475-484. 355 citations: Cardiac catheterisation guided by MRI in children and adults with ...
Funder rewrote the pathophysiolology of adrenal steroid action in the cardiovascular system, reshaping what we believe about ... They covered anaesthesia, tumours, the cardiovascular system and scleroderma. Basil Corkill described the methods of diagnosis ... He concluded "that the body's fluid system was an 'open system' with an intake and output and divisions of the contents under ... no system in the human body is more important than our immune system Obesity and Lipids: Alterations in how we metabolise fats ...
During HRV biofeedback, these two reflexes stimulate each other, stimulating resonance properties of the cardiovascular system ... a preliminary study of resonance in the cardiovascular system". Applied Psychophysiology and Biofeedback. 27 (1): 1-27. doi: ... "Research of the resonance characteristics for the cardiovascular system". Human Physiology. 9: 257-265. Chernigovskaya NV, ... Hinduism: Biofeedback systems have been known in India and some other countries for millennia. Ancient Hindu practices like ...
A clinician user of NIR HEG, Jeffrey Carmen, adapted Toomim's system for migraines in 2002 by integrating peripheral thermal ... It is widely known that regular cardiovascular exercise results in increased cerebral blood flow due to increased ... He developed a device specific to this measure that he called a Near Infrared Spectrophotometry Hemencephalography system, ... for him to function successfully in school and offering a quick and relatively cheap treatment alternative for school systems ...
"Cardiovascular and Renal Outcomes of Renin-Angiotensin System Blockade in Adult Patients with Diabetes Mellitus: A Systematic ... cardiovascular outcomes and adverse events in patients with diabetes and cardiovascular disease or risk: A systematic review ... "In Lee M (ed.). Basic Skills in Interpreting Laboratory Data (5th ed.). Bethesda, MD: American Society of Health-System ... The use of aspirin to prevent cardiovascular disease in diabetes is controversial.[114] Aspirin is recommended in people at ...
"An alternative medical system is a set of practices based on a philosophy different from Western biomedicine."[17] ... "Intercessory Prayer and Cardiovascular Disease Progression in a Coronary Care Unit Population: A Randomized Controlled Trial". ... Unscientific belief systems. Alternative medicine, such as using naturopathy or homeopathy in place of conventional medicine, ... Boundaries within CAM and between the CAM domain and the domain of the dominant system are not always sharp or fixed."[11] ...
In this system, particular proteins are targeted for destruction by the ligation of at least four copies of a small peptide ... and decrease cardiovascular risks (Nissen et al., 2000). For all these reasons, HMB should be routinely used in muscle-wasting ... and decrease cardiovascular risks (Nissen et al., 2000). For all these reasons, HMB should be routinely used in muscle-wasting ...
A hypoxicator is a medical device intended to provide a stimulus for the adaptation of an individual's cardiovascular system by ... who pioneered normobaric hypoxic altitude training systems. Most of these systems have not been cleared for medical ... Good brands have pulse oximeters integrated into the system and the best hypoxicators are equipped with automated biofeedback ... Manukhina EB, Downey HF, Mallet RT (April 2006). "Role of nitric oxide in cardiovascular adaptation to intermittent hypoxia". ...
Cardiovascular. *Pneumopericardium. *Persistent fetal circulation. Haemorrhagic and. hematologic disease. *Vitamin K deficiency ... By system. Respiratory. *Intrauterine hypoxia. *Infant respiratory distress syndrome. *Transient tachypnea of the newborn ...
... and found a serious cardiovascular adverse reaction rate of about 1 in 1500.[44] This study reported a cardiovascular-related ... Operations/surgeries and other procedures of the blood and lymphatic system (ICD-9-CM V3 40-41, ICD-10-PCS 07) ... This treatment also has an immunosuppressive effect that prevents rejection of the HSC by the recipient's immune system. The ... For this same group, severe cardiovascular events were observed with a rate of about 1 in 1500. The most common severe adverse ...
Review of systems (ROS) or systems inquiry: a set of additional questions to ask, which may be missed on HPI: a general enquiry ... Surgery has many sub-specialties, including general surgery, ophthalmic surgery, cardiovascular surgery, colorectal surgery, ... Immunology is the study of the immune system, which includes the innate and adaptive immune system in humans, for example. ... Well-known spiritual systems include animism (the notion of inanimate objects having spirits), spiritualism (an appeal to gods ...
Cardiac & Cardiovascular Systems. 88 Chemistry. 143 Clinical Medicine. 45 Computer Science. 181 ... In all, the Ohio State library system encompasses 55 branches and specialty collections. Some more significant collections ... Not to be confused with Ohio University or University System of Ohio. ... The residence hall system has 40 smaller living and learning environments defined by social or academic considerations. ...
Angiography is the use of fluoroscopy to view the cardiovascular system. An iodine-based contrast is injected into the ... This blurring can be measured as a contribution to the modulation transfer function of the imaging system. ...
Endocrine system. *Exercise and androgen levels. *Androgen insensitivity syndrome. *Testosterone and the cardiovascular system ...
"Preparing a Complaints/eMDR System for Upcoming FDA Mandate". Sparta Systems. 18 May 2015.. ... Of the 113 devices recalled, 35 were for cardiovascular issues.[38] This may lead to a reevaluation of FDA procedures and ... "Embedded Systems Design. Retrieved 2016-04-21.. *^ FDA (2010-09-08). "Infusion Pump Software Safety Research at FDA". FDA. ... EN 868 Packaging materials and systems for medical devices to be sterilized, General requirements and test methods ...
... ingestion of large amounts of potassium compounds can lead to hyperkalemia strongly influencing the cardiovascular system.[232] ... In the Solar SystemEdit. Estimated abundances of the chemical elements in the Solar system. Hydrogen and helium are most common ... In both the old IUPAC and the CAS systems for group numbering, this group is known as group IA (pronounced as "group one A", as ... I. A New Periodic System Which Shows a Relation Between the Abundance of the Elements and the Structure of the Nuclei of Atoms" ...
Cardiovascular. *Cardiac examination. *Peripheral vascular examination. *Heart sounds. *Other *Abdominojugular test. *Ankle- ... Tests and procedures involving the digestive system. Digestive system surgery. Digestive tract. ...
"Nutrition, Metabolism and Cardiovascular Diseases. 17 (2): 125-139. doi:10.1016/j.numecd.2006.10.005. PMC 4426988. PMID ... In the central nervous system, the three outer membranes (the meninges) that envelop the brain and spinal cord are composed of ... Mixed connective tissue disease - a disease of the autoimmune system, also undifferentiated connective tissue disease. ... Connective tissue is found in between other tissues everywhere in the body, including the nervous system. ...
... "cardiovascular system" (ID 1844), "mental state and performance" (ID 1845), and "liver, kidneys" (ID 1846) pursuant to Article ... "The metabolism and analysis of isoflavones and other dietary polyphenols in foods and biological systems". (review). Food & ...
Plato also compares the three parts of the soul or psyche to a societal caste system. According to Plato's theory, the three- ... particularly in the fields of cardiovascular and neurology.[101] In the two dominant conflicting concepts of the soul - one ... In a loss-of-function (also called "necessity") experiment, a part of the nervous system is diminished or removed in an attempt ... The opposition of flesh and spirit is accentuated afresh (Romans 1:18, etc.). This Pauline system, presented to a world already ...
Cardiovascular system *Pericarditis. *Hypertension. *Low blood pressure. *Fast heart rate. *Respiratory tract *Cough ...
Cardiovascular disease[edit]. Main articles: Occupational stress and Cardiovascular disease. Research has identified health- ... DeQuattro, V., & Hamad, R. (1985). The role of stress and the sympathetic nervous system in hypertension and ischemic heart ... Research has suggested that job loss adversely affects cardiovascular health[20][82] as well as health in general.[83][84] ... Job-related burnout and cardiovascular health[edit]. Main article: Occupational burnout. There is evidence from a prospective ...
Loss of immune system function. *Increased cardiovascular risks[30]. The isolation of a small population for a period of time ... Each individual will have similar immune systems, as immune systems are genetically based. When a species becomes endangered, ... Thus, similar immune systems may be more vulnerable to infectious diseases (see Major histocompatibility complex and sexual ... Fareed M, Afzal M (April 2016). "Increased cardiovascular risks associated with familial inbreeding: a population-based study ...
... cardiovascular, and nervous system, as well as the eyes and lungs.[36] ... that affects multiple systems, such as the nervous and integumentary system.[2] Other examples of pleiotropy are albinism, ... Unconverted phenylalanine builds up in the bloodstream and can lead to levels that are toxic to the developing nervous system ... of known causes of death in diagnosed patients relating to cardiovascular complications and congestive cardiac failure. Other ...
Alibardi, Lorenzo (2010). Morphological and cellular aspects of tail and limb regeneration in lizards a model system with ... "Reptilian cardiovascular anatomy and physiology: evaluation and monitoring (Proceedings)". dvm360.com. Retrieved 2017-04-22.. ... Respiratory systemEdit. All reptiles breathe using lungs. Aquatic turtles have developed more permeable skin, and some species ... The reptilian nervous system contains the same basic part of the amphibian brain, but the reptile cerebrum and cerebellum are ...
2006). "Effects of low-carbohydrate vs low-fat diets on weight loss and cardiovascular risk factors: a meta-analysis of ... carbon dioxide is expelled through the respiratory system. ... 2006). "Low-fat dietary pattern and risk of cardiovascular ... "Comparison of 4 Diets of Varying Glycemic Load on Weight Loss and Cardiovascular Risk Reduction in Overweight and Obese Young ... is associated with increased risk of cardiovascular disease.[30] ... no reduction in cardiovascular disease[38]. *no statistically ...
This cardiovascular system article is a stub. You can help Wikipedia by expanding it.. *v ...
Diseases and disorders of the cardiovascular system. *Diseases. Navigation menu. Personal tools *Not logged in ...
Tikal K, Hrabánková M (June 1993). "[Indications for antidepressive agents in relation to diseases of the cardiovascular system ... No evidence for a possible hepatic or cardiovascular toxicity was found.. History[edit]. Irreversible MAOI antidepressants were ... 1998). "cAMP-dependent phosphorylation system after short and long-term administration of moclobemide". J Psychiatr Res. 32 (2 ... when cardiovascular toxicity is a concern, SSRIs or the reversible MAOIs such as moclobemide are an option as they lack or have ...
"Introduction to Respiratory & Cardiovascular Physiology. University of the West of England, Bristol. 2016. Retrieved January 29 ... "The American Society of Health-System Pharmacists. Retrieved Dec 29, 2016.. Retrieved from "https://simple.wikipedia.org/w/ ...
Balas, E A. (2001). "Information Systems Can Prevent Errors and Improve Quality". Journal of the American Medical Informatics ... including the risk of breast cancer and cardiovascular disease, and are more efficacious than their synthetic and animal ...
The lymphatic system drains this excess.. J. Rodney Levick argues in his textbook that the interstitial force is often ... Levick, J (2010). Introduction to Cardiovascular Physiology. 5th edition. London: Hodder Arnold. p. 190. ISBN 978 0340 942 048. ... It is now appreciated that the ultrafilter is the endothelial glycocalyx layer whose interpolymer spaces function as a system ...
... including the metabolic system, cardiovascular system, immune system, reproductive system and central nervous system. The HPA ... Immune system[edit]. There is bi-directional communication and feedback between the HPA axis and immune system. A number of ... The HPA axis, HPG axis, HPT axis, and the hypothalamic-neurohypophyseal system are the four major neuroendocrine systems ... At the hypothalamus, fear-signaling impulses activate both the sympathetic nervous system and the modulating systems of the HPA ...
... circulatory system [1]*) (kar-di-oh-*vas*-kew-ler) n.* the heart together with two networks of blood vessels - the systemic ... Cardiovascular System World of Sports Science COPYRIGHT 2007 Thomson Gale. Cardiovascular System. The cardiovascular system is ... Cardiovascular System. Definition. The cardiovascular system includes the heart and the blood vessels and is responsible for ... the cardiovascular system is interconnected with two other heart-centered systems: the cardiopulmonary system, which controls ...
The Cardiovascular System Dynamics Society (CSDS), founded on 5 October 1976 in Philadelphia, Pennsylvania, by organ system ... cardiovascular biology, clinical disease, and modeling. The primary theme remains cardiovascular function, its physiologic and ... physiologist and biomedical engineers, was a historic first in its mathematical and quantitative approach to cardiovascular ...
Impact of the National Health Service Health Check on cardiovascular disease risk: a difference-in-differences matching ...
Vigna, GB; Bergami, E (2005). "Testosterone replacement, cardiovascular system and risk factors in the aging male". Journal of ... "Testosterone and the Cardiovascular System: A Comprehensive Review of the Clinical Literature". Journal of the American Heart ... Previously, the higher cardiovascular risk in men has been attributed in part to the negative effects of systemic testosterone ... "The risk of Cardiovascular Events in Men Receiving Testosterone Therapy: An Endocrine Society Statement" (PDF). Endocrine ...
... identify parts of the cardiovascular system and examine blood flow. Be sure to click heart (it beats) for an enlarged view of ... Animation: identify parts of the cardiovascular system and examine blood flow. Be sure to click heart (it beats) for an ... Animation: identify parts of the cardiovascular system and examine blood flow. Be sure to click heart (it beats) for an ... describe the interactions that occur among systems that perform the functions of regulation, nutrient absorption, reproduction ...
Source for information on Biomedicine and Health: The Cardiovascular System: Scientific Thought: In Context dictionary. ... The Cardiovascular SystemIntroductionIn modern science the brain is the key to our identity. The head is the seat of thought ... Cardiovascular Components: The Pulmonary System The pulmonary circulatory system delivers deoxygenated blood from the right ... Cardiovascular Components: Veins and the Venous System Veins are vessels designed to collect and return blood, including ...
... also known as the circulatory system) with our detailed diagrams and information. ... Explore the anatomy of the human cardiovascular system ( ... Cardiovascular System (Male View). *Cardiovascular System (Male ... Cardiovascular System Physiology. Functions of the Cardiovascular System. The cardiovascular system has three major functions: ... Cardiovascular System Anatomy. The Heart. The heart is a muscular pumping organ located medial to the lungs along the bodys ...
Cardiovascular System Physiology. Functions of the Cardiovascular System. The cardiovascular system has three major functions: ... Cardiovascular System Anatomy. The Heart. The heart is a muscular pumping organ located medial to the lungs along the bodys ... The cardiovascular system consists of the heart, blood vessels, and the approximately 5 liters of blood that the blood vessels ... Protection: The cardiovascular system protects the body through its white blood cells. White blood cells clean up cellular ...
This test is often included in cardiovascular testing as an indicator of future risk of cardiovascular problems. ... 120188 - This lab test measures the level of Lipoprotein (a) within the blood, and is often part of a cardiovascular health/ ... CARDIO1 - This panel will test for multiple items that relate to cardiovascular health: Lipid Profile, Glucose, Hemoglobin A1c ...
... Jagdish N. Sharma Department of Applied Therapeutics, Faculty of ... All the components of the kallikrein-kinin system are located in the cardiac muscle andits deficiency may lead to cardiac ... suggestedthat the reduced activity of the local kallikrein-kinin system may be instrumental for theinduction of cardiovascular- ... In addition, stable kinin agonists may also be available in the future astherapeutic agents for cardiovascular and renal ...
Cardiovascular Systems shares have increased 41 percent since the beginning of the year. In the final minutes of trading on ... AP) _ Cardiovascular Systems Inc. (CSII) on Monday reported fiscal fourth-quarter profit of $3.7 million. ... Cardiovascular Systems expects full-year revenue in the range of $240 million to $250 million. ...
Anatomical System Theiler Stage Assay Type Detected? TPM Level Wild type? Gene Type Molecular Function Biological Process ...
Current Trends in Cardiovascular Research Cardiology Research and Clinical Developments, Cardiovascular System, Medicine and ... Horizons in World Cardiovascular Research (Numbered Series), Cardiovascular System, Medicine and Health ... Horizons in World Cardiovascular Research (Numbered Series), Cardiovascular System, Medicine and Health ... Horizons in World Cardiovascular Research (Numbered Series), Cardiovascular System, Medicine and Health ...
New Research in Cardiovascular Health Cardiology Research and Clinical Developments, Cardiovascular System, Medicine and Health ... Fitness and Cardiovascular Risk Factors - What Everyone Should Know Physical Fitness, Diet and Exercise, Cardiovascular System ... Cardiovascular Health and Chronomics Cardiology Research and Clinical Developments, Cardiovascular System, Medicine and Health ... Horizons in World Cardiovascular Research (Numbered Series), Cardiovascular System, Medicine and Health ...
We are incredibly proud of our network of alumni who are advancing cardiovascular care in all regions of the country and world ...
University of Michigan Health System:. The University of Michigan Health System includes the U-M Medical School, with its ... Cardiovascular Surgery ICU Inpatient Heart Failure/Transplant. Nuclear Cardiology. Echocardiography (VA). Vascular and ... In addition to the above rotations, fellows maintain continuity clinics at the University of Michigan Health System, and the VA ... Frankel Cardiovascular Center, C.S. Mott Childrens Hospital, Von Voigtlander Womens Hospital, 120 outpatient clinics and ...
Cardiovascular Systems, Inc. (CSII) : Free Stock Analysis Report. Lantheus Holdings, Inc. (LNTH) : Free Stock Analysis Report. ... Medical device manufacturer Cardiovascular Systems, Inc. CSII recently released one-year data from its LIBERTY 360° clinical ... Since 1988, the Zacks system has more than doubled the S&P 500 with an average gain of +25% per year. With compounding, ... But heres something even more remarkable: You can master this proven system without going to a single class or seminar. And ...
Add Cardiovascular Systems to My Watchlist.. The article Taking Stock of Cardiovascular Systems originally appeared on Fool.com ... Is Cardiovascular Systems the best health care stock for you? Learn how to maximize your investment income and "Secure Your ... How is Cardiovascular Systems doing by this quick checkup? At first glance, pretty well. Trailing-12-month revenue increased ... Is the current inventory situation at Cardiovascular Systems (NAS: CSII) out of line? To figure that out, start by comparing ...
This reports purpose is to detail the cardiovascular disease (CVD) burden on remote and rural Australia, and to propose action ... How can you moderate dietary fat intake to protect against cardiovascular disease? This review examined the evidence for the ... This report highlights that people with cardiovascular disease require aggressive management of their risk factors to prevent ... Electronic clinical decision support tool for the evaluation of cardiovascular risk in general practice: a pilot study ...
Your bodys transportation system by Elizabeth Bailey , This newsletter was created with Smore, an online tool for creating ... The circulatory system or cardiovascular system is a long system of veins, arteries, arterioles, venules, and capillaries ... Almost everything uses the cardiovascular system as a transportation system. As the blood loses oxygen it goes from high ... Cardiovascular Respiratory deals with oxygen exchange and heart circulates blood throughout body. *Both have a vital sign ...
Find out how high blood glucose can impact the cardiovascular and nervous systems, sexual and mental health, and other aspects ... Circulatory and cardiovascular systems. High blood glucose levels can cause damage to all parts of the cardiovascular system. ... The cardiovascular system. According to the CDC, cardiovascular disease is the leading cause of early death among people with ... Digestive system. Symptoms of gastroparesis include bloating and abdominal pain.. Damage to the nervous system can affect ...
"Building a Fully Integrated Cardiovascular Imaging and Information System" Webinar will be held on Thursday, July 24, 10am PDT ... "Building a Fully Integrated Cardiovascular Imaging and Information System" is part of the Success In CVIS Webinar Series, ... "Building a Fully Integrated Cardiovascular Imaging and Information System" is essential viewing for heart centers looking for ... Attend "Building a Fully Integrated Cardiovascular Imaging and Information System" and learn how they did it. ...
Circulatory System Why is the circulatory system called the cardiovascular system. ?. The cardiovascular system consists of the ... Cardiovascular Health Is the cardiovascular system important. ?. yes becouse the cardiovascular system is the delivary system ... Cardiovascular disease affects the cardiovascular system. The cardiovascular system is also known as the circulatory system. ... Cardiovascular Health. , Fitness Why is the cardiovascular system important to teens. ?. Um, the cardiovascular system is ...
The filtered signals may be used for generating an image of the at least portion of the cardiovascular system. ... not arising from cardiovascular sounds has been removed. ... in at least a portion of an individuals cardiovascular system ... A method and system for analyzing sounds originating ... Method and system for analyzing cardiovascular sounds. US ... a system and method for recording and analyzing cardiovascular sounds produced in the cardiovascular system. The system ...
Here we highlight the importance of the circadian system to normal cardiovascular function and to cardiovascular disease, and ... and vasculature prepare the cardiovascular system for optimal function during these anticipated behavioral cycles. ... Cardiovascular circadian rhythms, however, may be a double-edged sword. The normal amplified responses in the morning may aid ... Furthermore, chronic disruptions of the circadian clock, as with night-shift work, contribute to increased cardiovascular risk ...
Philips IntelliSpace Cardiovascular System and Xcelera System Vulnerability. Original release date: November 14, 2017 ... The Philips IntelliSpace Cardiovascular and Xcelera systems (a predecessor to IntelliSpace Cardiovascular) are comprehensive ... According to Philips, IntelliSpace Cardiovascular and Xcelera systems are deployed across the Healthcare and Public Health ... IntelliSpace Cardiovascular and Xcelera cardiac image and information management systems. Philips has produced updates that ...
Akt1 in the cardiovascular system: friend or foe?. Brian T. ONeill and E. Dale Abel Division of Endocrinology, Metabolism and ... In this installment of "Akt in the cardiovascular system," Akt1 has clearly emerged as the star of Act 1. We are sure that Act ... In the cardiovascular system, Akt plays an important role in the regulation of cardiac hypertrophy, angiogenesis, and apoptosis ... Another unresolved issue in the cardiovascular system was the specific role of the 3 Akt isoforms. For example, while it was ...
The CD40-CD40L system in cardiovascular disease.. Pamukcu B1, Lip GY, Snezhitskiy V, Shantsila E. ... The CD40-CD40L system is a pathway which is associated with both prothrombotic and proinflammatory effects. CD40 and its ligand ... Concentrations of sCD40L also predict risk of future cardiovascular disease in healthy women and clinical outcomes in patients ... University of Birmingham Centre for Cardiovascular Sciences , City Hospital, Birmingham, England UK.. ...
Positive Market Trends Aid Cardiovascular Systems Amid Woes. Jan 18 / Zacks.com - Paid Partner Content ... Factset: FactSet Research Systems Inc. . All rights reserved. Chicago Mercantile Association: Certain market data is the ...
6 contractor salaries for 5 jobs at Terumo Cardiovascular Systems. Contractor Salaries posted anonymously by Terumo ... A free inside look at Terumo Cardiovascular Systems contractor salary trends. ... See Terumo Cardiovascular Systems Salaries, Terumo Cardiovascular Systems Hourly Pay, Terumo Cardiovascular Systems Bonuses, or ... check out salaries for Terumo Cardiovascular Systems Internship.. Terumo Cardiovascular Systems Salaries by Location ...
  • cardiovascular system ( circulatory system ) (kar-di-oh- vas -kew-ler) n. the heart together with two networks of blood vessels - the systemic circulation and the pulmonary circulation. (encyclopedia.com)
  • cardiovascular system: see circulatory system . (encyclopedia.com)
  • The endothelium lines the entire circulatory system, all the way to the interior of the heart, where it is called the endocardium. (innerbody.com)
  • Hemodynamics is the study of dynamics in the circulatory system. (novapublishers.com)
  • In this module we consider how the circulatory system works to deliver oxygen and nutrients to the specific organs. (coursera.org)
  • The circulatory system or cardiovascular system is a long system of veins, arteries, arterioles, venules, and capillaries including the heart surrounded by the pericardium all contribute to getting nutrients and oxygen to every cell in the body. (smore.com)
  • Without the circulatory system in optimal health, our entire body is at risk. (smore.com)
  • Some sources consider these two to be one system, the circulatory system, because they both "circulate" fluids in the body. (answers.com)
  • The cardiovascular system is also known as the circulatory system. (answers.com)
  • But is the spleen a part of the circulatory system? (answers.com)
  • The lymphatic system is a sub-system of the circulatory system that basically helps fight infection, recycle blood plasma, etc. (answers.com)
  • Most people do not think of the lymphatic system as part of the circulatory system though (even though it is) and most use the words "circulatory" and "cardiovascular" interchangeably (even though they're not interchangeable). (answers.com)
  • There are 4 parts of the Circulatory or Cardiovascular System. (answers.com)
  • The main part is the Circulatory/Cardiovascular System (heart, blood vessels, blood. (answers.com)
  • The circulatory system and the respiratory system work closely together to ensure that organ tissues receive enough oxygen. (ehow.co.uk)
  • Texas Heart Institute: How Does Exercise Affect the Circulatory System? (ehow.co.uk)
  • Americans today have many options to take care of their heart and circulatory system. (wikibooks.org)
  • The mammalian circulatory system comprises both the cardiovascular system and the lymphatic system. (nih.gov)
  • The cardiovascular system is part of your larger circulatory system. (scai.org)
  • The cardiovascular (or circulatory) system supplies oxygen from the air that we inspire, via the lungs to the tissues around the body. (indigo.ca)
  • Your heart, blood and blood vessels together make up your cardiovascular system (or heart and circulatory system). (nationwidepharmacies.co.uk)
  • ST. PAUL, Minn. (AP) _ Cardiovascular Systems Inc. (CSII) on Monday reported fiscal fourth-quarter profit of $3.7 million. (yahoo.com)
  • Medical device manufacturer Cardiovascular Systems, Inc. CSII recently released one-year data from its LIBERTY 360° clinical study in a late-breaking presentation at the 2017 Amputation Prevention Symposium (AMP) in Chicago. (yahoo.com)
  • ST. PAUL, Minn.--( BUSINESS WIRE )--Cardiovascular Systems, Inc. (CSI) (NASDAQ: CSII), today announced that it has received PMA approval from the U.S. Food and Drug Administration (FDA) to market its Diamondback 360 ® Coronary Orbital Atherectomy System (OAS) as a treatment for severely calcified coronary arteries. (businesswire.com)
  • Cardiovascular Systems, Inc. CSII was a big mover last session, as the company saw its shares rise nearly 7% on the day. (nasdaq.com)
  • CSII ) , a medical device company focused on developing and commercializing innovative interventional treatment systems for vascular disease, today announced the pricing of an underwritten public offering of 2,000,000 shares of its common stock, at a price to the public of $17.60 per share. (aol.com)
  • Cardiovascular Systems (NSDQ:CSII) posted first-quarter results that beat the consensus on Wall Street. (massdevice.com)
  • Cardiovascular Systems (NSDQ:CSII) shares ticked up after hours today on fourth-quarter results that came in ahead of the consensus forecast. (massdevice.com)
  • Cardiovascular Systems (NSDQ:CSII) announced today that underwriters fully exercised their option in an offering, leading to proceeds of $143.7 million. (massdevice.com)
  • Cardiovascular Systems (NSDQ:CSII) announced that it commenced an underwritten public offering of common stock shares worth $125 million. (massdevice.com)
  • Cardiovascular Systems (NSDQ:CSII) shares dropped today on COVID-19-affected first-quarter results that missed the consensus forecast. (massdevice.com)
  • Cardiovascular Systems (NSDQ:CSII) shares sank today after the medical device company missed the consensus earnings forecast for its fiscal first quarter. (massdevice.com)
  • Cardiovascular Systems (NSDQ:CSII) said today that it won pre-market approval from the FDA for a new ViperWire Advance coronary guidewire for orbital atherectomies using its Diamondback 360 device. (massdevice.com)
  • Cardiovascular Systems (CSII) Up 6.2% Since Last Earnings Report: Can It Continue? (nasdaq.com)
  • I t has been about a month since the last earnings report for Cardiovascular Systems (CSII). (nasdaq.com)
  • In recent years, numerous observationsobtained from clinical and experimental models of diabetes, hypertension, cardiacfailure, ischemia, myocardial infarction, and left ventricular hypertrophy have suggestedthat the reduced activity of the local kallikrein-kinin system may be instrumental for theinduction of cardiovascular-related diseases. (hindawi.com)
  • The ability of kallikrein gene delivery to produce a wide spectrum of beneficialeffects makes it a promising candidate in treating hypertension and cardiovascular andrenal diseases. (hindawi.com)
  • Hemodynamics has been essential in clinical practice pertaining to cardiovascular diseases from ancient days. (novapublishers.com)
  • Although it is essential because it is based on dynamics and physics, the understanding of hemodynamics is hard for all those concerned with cardiovascular diseases. (novapublishers.com)
  • Although successful efforts have been greatly exerted to prevent and treat cardiovascular diseases (CVDs), it currently causes the most number of global deaths among all kinds of diseases. (novapublishers.com)
  • Cardiovascular diseases are the leading cause of death in almost 40% of patients suffering from end stage renal disease (ESRD). (novapublishers.com)
  • According to recent studies and statistics, cardiovascular diseases (CVD) are among the most frequent cause of death. (embedded.com)
  • We choose to monitor this parameter due to major incidence and impact of cardiovascular diseases (CVD). (embedded.com)
  • Our mission is to build healthier lives, free of cardiovascular diseases and stroke. (ahajournals.org)
  • Across the globe, the adoption of CVIS solutions is increasing, due to factors such as the requirement to reduce the mortality rate due to cardiovascular diseases, necessity to streamline the cardiac care workflow in healthcare organizations, and overcome the issues with data silos in cardiac departments. (marketsandmarkets.com)
  • Recent research has implicated the lymphatic system in the pathogenesis of cardiovascular diseases including obesity and metabolic disease, dyslipidemia, inflammation, atherosclerosis, hypertension, and myocardial infarction. (nih.gov)
  • This is why diseases of the cardiovascular system put people at risk for a number of conditions, such as heart attack, stroke, kidney failure, and other serious illnesses. (scai.org)
  • His research interests generally focus on the influence of exercise on molecular mediators of cardiovascular diseases, with particular emphasis on blood coagulation and fibrinolysis. (acsm.org)
  • Increasing incidence of cardiovascular diseases is a major factor driving the market. (pitchengine.com)
  • The CVIS segment is projected to grow at the highest CAGR from 2015 to 2020, owing to the increasing incidence and prevalence of cardiovascular diseases. (marketsandmarkets.com)
  • Growth in the North American segment is primarily driven by strict privacy and security regulations, and increasing incidence of cardiovascular diseases. (marketsandmarkets.com)
  • Rising incidence of cardiovascular diseases, growing rate of medication errors, increasing government initiatives towards EHR implementation, rise in healthcare costs, and high adoption of CVIS in hospitals are driving the market growth. (marketsandmarkets.com)
  • Philips is producing software hotfix updates for all IntelliSpace Cardiovascular and latest Xcelera versions, some of which are available upon request, while other versions are in the process of development and are expected to be completed by the end of 2017. (us-cert.gov)
  • Currently the society includes investigators in muscle and vascular biology, subcellular and sarcomere dynamics, the microcirculation, cardiovascular biology, clinical disease, and modeling. (wikipedia.org)
  • Previously, the higher cardiovascular risk in men has been attributed in part to the negative effects of systemic testosterone, however, more recent research has highlighted the protective nature of testosterone against cardiovascular disease. (wikipedia.org)
  • Furthermore, recent research has linked testosterone replacement therapy to an increase in deaths and other cardiovascular occurrences in men whom document a history of coronary artery disease. (wikipedia.org)
  • Cardiovascular disease remains the leading cause of death in the developed world. (novapublishers.com)
  • By preventing thromboembolic events such as heart attacks and strokes, antiplatelet drugs have become a cornerstone in the treatment of cardiovascular disease. (novapublishers.com)
  • Takotsubo cardiomyopathy (TC) is a relatively new pathological concept in cardiovascular disease, originally described in the Japanese population at the beginning of the 1990s. (novapublishers.com)
  • This report highlights that people with cardiovascular disease require aggressive management of their risk factors to prevent secondary cardiovascular events. (apo.org.au)
  • People who are socioeconomically disadvantaged have, on average, greater levels of cardiovascular disease (CVD), diabetes and chronic kidney disease (CKD). (apo.org.au)
  • The objective of this research was to construct and compare a 2013 New Zealand population derived from Statistics New Zealand's Integrated Data Infrastructure (IDI) with the 2013 census population and a 2013 Health Service Utilisation population, and to ascertain the differences in cardiovascular disease prevalence. (apo.org.au)
  • This report's purpose is to detail the cardiovascular disease (CVD) burden on remote and rural Australia, and to propose action to ameliorate CVD impacts. (apo.org.au)
  • This study tests the acceptability and feasibility of an electronic medical record based clinical decision support tool for the evaluation of absolute cardiovascular disease risk in general practice. (apo.org.au)
  • How can you moderate dietary fat intake to protect against cardiovascular disease? (apo.org.au)
  • This review examined the evidence for the association between dietary fat consumption and cardiovascular disease (CVD). (apo.org.au)
  • These drugs can reduce the risk of high blood sugar and, therefore, cardiovascular disease. (medicalnewstoday.com)
  • These drugs can also reduce the risk of chronic kidney disease progression, cardiovascular events, or both. (medicalnewstoday.com)
  • Cardiovascular disease affects the cardiovascular system. (answers.com)
  • Here we highlight the importance of the circadian system to normal cardiovascular function and to cardiovascular disease, and identify opportunities for optimizing timing of medications in cardiovascular disease. (jci.org)
  • The CD40-CD40L system in cardiovascular disease. (nih.gov)
  • Concentrations of sCD40L also predict risk of future cardiovascular disease in healthy women and clinical outcomes in patients with acute coronary syndromes. (nih.gov)
  • Today is a landmark moment for: patients suffering from calcified coronary artery disease, their families, our physician operators and everyone at CSI," said David L. Martin, President and Chief Executive Officer of Cardiovascular Systems. (businesswire.com)
  • The genetic basis of cardiovascular function, development, and disease is an area of intense investigation, in the hope of significant insights into the heart and vessels? (cshlpress.com)
  • This fully accredited, three-year program provides superior, "hands on" training for physicians who wish to become highly skilled clinical cardiologists as well as educators and investigators in cardiovascular disease. (christianacare.org)
  • Thus, medical care of children with JIA should include strategies preventing cardiovascular disease by maintenance of adequate body weight. (hindawi.com)
  • Cardiovascular Systems, Inc., based in St. Paul, Minn., is a medical device company focused on developing and commercializing innovative solutions for treating vascular and coronary disease. (aol.com)
  • Shares of Cardiovascular Systems ,a medical device company with a focus on minimally invasive surgery products used to treat vascular disease, were down more than 20% in early trading after the company released preliminary results for the most recently completed quarter. (foxbusiness.com)
  • Cardiovascular Systems Inc. (CSI) is comprised of a highly experienced, uniquely qualified team of experts experienced in the assessment, development and commercialization of medical devices for treating peripheral arterial disease. (xconomy.com)
  • Illustration showing the categories for standardized reporting in the Coronary Artery Disease - Reporting and Data System (CAD-RADS). (massgeneral.org)
  • The new multi-societal CAD-RADS (Coronary Artery Disease Reporting and Data System) is designed to facilitate uniform standardization of reporting (Fig.2, 3). (massgeneral.org)
  • 2016) Coronary Artery Disease - Reporting and Data System (CAD-RADS): An Expert Consensus Document of SCCT, ACR and NASCI: Endorsed by the ACC. (massgeneral.org)
  • One reason is that it is a risk factor for cardiovascular disease, most notably hypertension. (clinicaltrials.gov)
  • Here, we review the most recent advances in the field of lymphatic vascular biology, with a focus on cardiovascular disease. (nih.gov)
  • In this review we have studied the relevant literature regarding several risk factors for cardiovascular disease where the effects of AAS have been scrutinized:(1) Echocardiographic studies show that supraphysiologic doses of AAS lead to both morphologic and functional changes of the heart. (nih.gov)
  • Taken together, various lines of evidence involving a variety of pathophysiologic mechanisms suggest an increased risk for cardiovascular disease in users of anabolic androgenic steroids. (nih.gov)
  • A study of peripheral vascular interventions in patients with peripheral artery disease (PAD) has demonstrated "high freedom" from major amputation at three years, according to study sponsor Cardiovascular Systems. (massdevice.com)
  • GE Healthcare, a unit of General Electric Company (NYSE: GE), has unveiled a new cardiovascular imaging system that will enhance clinicians' ability to diagnose and treat heart disease and enable more precise placement of interventional devices such as stents, balloons and filters. (highbeam.com)
  • Sparrow Cardiovascular and Thoracic Surgery is an integral part of Sparrow Heart and Vascular Center's advanced treatment options for cardiovascular disease, including comprehensive heart, lung, vascular and vein care. (sparrow.org)
  • In 1994, Villablanca founded the nation's first program dedicated to women's heart health - the UC Davis Women's Cardiovascular Medicine Program - with the goals of providing expert and supportive cardiac treatment for women and raising awareness of heart disease as the nation's leading cause of death among women. (ucdavis.edu)
  • Villablanca is at the forefront of understanding the unique attributes of and new treatment targets for cardiovascular disease in women. (ucdavis.edu)
  • Computational and mathematical modeling approaches especially are needed to move toward a more holistic understanding of mechanisms and treatment options for cardiovascular disease. (frontiersin.org)
  • Methods to improve cardiovascular disease risk stratification and prediction. (frontiersin.org)
  • Worldwide, cardiovascular disease remains a leading cause of death and a major cause of disability and lost productivity in adults. (frontiersin.org)
  • Published studies have described the SphygmoCor system's use in hypertension management, heart failure, kidney disease, high risk pregnancy, diabetic care, drug therapy management, cardiovascular risk stratification and a wide range of other applications. (medicalsearch.com.au)
  • HOUSTON--( BUSINESS WIRE )--Saranas, a medical device company with a cutting-edge technology for real-time detection and monitoring of internal bleeding during endovascular procedures, placed first runner-up at the Cardiovascular Research Technologies (CRT) competition on March 6, 2018, in Washington, D.C. (businesswire.com)
  • VNA [On-premise Software, Hybrid & Cloud, Multi-Department & Multi-Site VNA] & Picture Archiving and Communication System [Enterprise, Cardiology & Radiology] - Global Forecast to 2018. (pitchengine.com)
  • The cardiovascular system consists of the heart, blood, and blood vessels, like veins and arteries. (answers.com)
  • Cardiovascular Systems' revolutionary, new Diamondback 360(R) Coronary Orbital Atherectomy System, was recently approved by the U.S. Food and Drug Administration to treat severely calcified lesions in coronary arteries. (businesswire.com)
  • My main health concerns include risk of possible liver damage, cardiovascular damage, ( arteries, heart, and lungs ) and even brain damage. (doctorslounge.com)
  • With its complex pathways of veins, arteries, and capillaries, the cardiovascular system keeps life pumping through you. (cliffsnotes.com)
  • To find out more about Synapse Cardiovascular's echocardiography tools, visit the Synapse Cardiovascular website . (fujifilmusa.com)
  • The premium-performance ACUSON S2000™ Cardiovascular (CV) Ultrasound System is equipped with everything you need to con﫿dently diagnose even the toughest cardiology cases and to run your practice with ultimate ease and ef﫿ciency. (news-medical.net)
  • Histology flashcards: The cardiovascular System is available for download from Apple Books. (apple.com)
  • Radiology Information Systems Market by Type (Integrated, Standalone), Deployment Mode (Web based, On-Premise, Cloud-Based), End User (Hospitals, Office based Physicians, Emergency Healthcare Service Providers) and by Component - Global Trends & Forecast to 2019. (pitchengine.com)
  • How much do Terumo Cardiovascular Systems employees make? (glassdoor.com)
  • See Terumo Cardiovascular Systems Salaries , Terumo Cardiovascular Systems Hourly Pay , Terumo Cardiovascular Systems Bonuses , or check out salaries for Terumo Cardiovascular Systems Internship . (glassdoor.com)
  • ANN ARBOR, Mich. , March 22, 2011 /PRNewswire/ -- Terumo Cardiovascular Systems (Terumo CVS), a U.S.-based subsidiary of Terumo Corporation of Tokyo, Japan , today announced it has agreed to the terms of a consent decree with the U.S. Food & Drug Administration (FDA) regarding quality system improvements at the company's Ann Arbor, Michigan facility. (prnewswire.com)
  • Terumo Cardiovascular Systems Corporation is a global manufacturer and marketer of medical devices for cardiac and vascular surgery. (prnewswire.com)
  • As of June 24, 2020, the I-Share catalog and your local library catalog have moved to a new system! (illinois.edu)
  • Cardiovascular Systems, Inc. reported a loss per share of 17 cents in first-quarter fiscal 2020, wider than the loss per share of 9 cents in the prior-year period. (nasdaq.com)
  • Cardiovascular Systems reaffirmed its fiscal 2020 guidance. (nasdaq.com)
  • Fully integrated with third-party hemodynamic monitoring systems, Synapse Cardiovascular provides cardiac catheterization specialists with immediate access to wave forms and clinical information. (fujifilmusa.com)
  • Christiana Care offers an academic and clinical fellowship in cardiovascular medicine. (christianacare.org)
  • Our aim is to prepare clinical cardiologists to provide state-of-the-art cardiovascular care that recognizes the shared humanity between doctor and patient, family and loved ones. (christianacare.org)
  • This concise and accessible text provides an integrated overview of the cardiovascular system - considering the basic sciences which underpin the system and applying this knowledge to clinical practice and therapeutics. (wiley.com)
  • A general introduction to the cardiovascular system is followed by chapters on key topics such as anatomy and histology, blood and body fluids, biochemistry, excitation-contraction coupling, form and function, integration and regulation, pathology and therapeutics, clinical examination and investigation - all supported by clinical cases for self-assessment. (wiley.com)
  • It covers topics under Clinical Impact of Cardiovascular Physiology and Pathophysiology. (indigo.ca)
  • The first project tested the effectiveness of community-based interventions on improving cardiovascular outcomes among high-risk women, and the second one evaluated evidence-based women's heart-health programs on improving clinical outcomes. (ucdavis.edu)
  • Used in research, patient care, and in pharmaceutical clinical trials worldwide, SphygmoCor CVMS system allows clinicians and researchers to measure the pressures the heart, brain and kidneys actually experience. (medicalsearch.com.au)
  • The SphygmoCor CP system is portable, lightweight and is suitable for use in every clinical setting, including home care and military applications. (medicalsearch.com.au)
  • The magnitude and mechanism of action by which low testosterone in men is influential in the pathogenesis of cardiovascular risk and the potential benefits of testosterone therapy has yet to be fully determined. (wikipedia.org)
  • Responsible for transporting oxygen, nutrients, hormones, and cellular waste products throughout the body, the cardiovascular system is powered by the body's hardest-working organ - the heart, which is only about the size of a closed fist. (innerbody.com)
  • In this course, students learn to recognize and to apply the basic concepts that govern integrated body function (as an intact organism) in the body's nine organ systems. (coursera.org)
  • Then they are removed by your The body's immune system. (doctorslounge.com)
  • The cardiovascular system has three major functions: transportation of materials, protection from pathogens, and regulation of the body's homeostasis. (nationwidepharmacies.co.uk)
  • The cardiovascular system transports blood to almost all of the body's tissues. (nationwidepharmacies.co.uk)
  • The cardiovascular system is instrumental in the body's ability to maintain homeostatic control of several internal conditions. (nationwidepharmacies.co.uk)
  • Animation: identify parts of the cardiovascular system and examine blood flow. (curriki.org)
  • High blood glucose levels can cause damage to all parts of the cardiovascular system. (medicalnewstoday.com)
  • Lungs are the primary organ in the respiratory system. (ehow.co.uk)
  • The bronchioles are branches off the trachea that span the lobes of the lungs in the respiratory system. (ehow.co.uk)
  • When understanding how the cardiovascular system works with the respiratory system, these parts of the lungs are the main site for cardiovascular and respiratory interaction. (ehow.co.uk)
  • There is a related system to the cardiovascular system called the lymphatic system which moves lymphatic fluid through the spleen, lymphatic tissues, and lymphatic vessels. (answers.com)
  • Having a user-friendly device available to effectively treat severe coronary calcium may increase the safety of CAD interventions for this difficult to treat population, while improving long-term patient prognoses," said Dr. Gregg Stone, Professor of Medicine, Columbia University, Director of Cardiovascular Research and Education Center for Interventional Vascular Therapy New York Presbyterian Hospital/Columbia University Medical Center and Co-Director of The Cardiovascular Research Foundation New York, N.Y. (businesswire.com)
  • However, to date there are no prospective, randomized, interventional studies on the long-term cardiovascular effects of abuse of AAS. (nih.gov)
  • The Innova 4100 and Innova 3100 cardiovascular and interventional imaging systems use an automated imaging technique called InnovaBreeze. (highbeam.com)
  • Boston Scientific Corp. has announced collaborations with Philips Healthcare and Siemens Medical Solutions to enable the use of its iLab Ultrasound Imaging System with the Philips Allura Xper and the Siemens Axiom Artis and Artis zee interventional X-ray systems. (highbeam.com)
  • These results support the need for further investigation of the short- and long-term cardiovascular effects of mental calm and individualized ways to achieve it. (frontiersin.org)
  • Geographically, the cardiovascular information system market was dominated by North America, followed by Europe. (pitchengine.com)
  • CARDIO1 - This panel will test for multiple items that relate to cardiovascular health: Lipid Profile, Glucose, Hemoglobin A1c, Fasting Insulin, Vitamin D 25-Hydroxy, C-Reactive Protein (Cardiac or High Sensitivity), Homocysteine, and Fibrinogen. (mcssl.com)
  • 120188 - This lab test measures the level of Lipoprotein (a) within the blood, and is often part of a cardiovascular health/risk testing. (mcssl.com)
  • In addition to the above rotations, fellows maintain continuity clinics at the University of Michigan Health System, and the VA Health System. (umich.edu)
  • Each year the cardiology fellows collectively invite an expert clinician as a visiting professor to the University of Michigan Health System. (umich.edu)
  • Is Cardiovascular Systems the best health care stock for you? (aol.com)
  • According to Philips, IntelliSpace Cardiovascular and Xcelera systems are deployed across the Healthcare and Public Health sector. (us-cert.gov)
  • Credentials are stored in cleartext in system files that may allow an attacker with elevated privileges to gain unauthorized access to data to include patient health information, system resources, and misuse of connected assets. (us-cert.gov)
  • Christiana Care is a private not-for-profit regional health care system and relies in part on the generosity of individuals, foundations and corporations to fulfill its mission. (christianacare.org)
  • Cardiovascular exercise is one key component to becoming, and staying, more physically fit, with many positive short-term and long-term effects on general health and fitness. (ehow.co.uk)
  • Cardiovascular exercise has also been proven to have many short- and long-term health benefits. (ehow.co.uk)
  • To maintain cardiovascular health, the American College of Sports Medicine recommends getting at least 30 minutes of moderate aerobic exercise on five or more days per week, or at least 20 minutes of vigorous exercise on three or more days per week. (livestrong.com)
  • Odom EC, Fang J, Zack M, Moore L, Loustalot F. Associations Between Cardiovascular Health and Health-Related Quality of Life, Behavioral Risk Factor Surveillance System, 2013. (cdc.gov)
  • The American Heart Association established 7 cardiovascular health metrics as targets for promoting healthier lives. (cdc.gov)
  • All measures of cardiovascular health and health-related quality of life were self-reported. (cdc.gov)
  • The 7 ideal cardiovascular health metrics were normal blood pressure, cholesterol, body mass index, not having diabetes, not smoking, being physically active, and having adequate fruit or vegetable intake. (cdc.gov)
  • Regardless of the cause of your problems, there are steps that you can take to improve your cardiovascular health. (fibromyalgia-symptoms.org)
  • The critical nature of this connection is exemplified by stress-induced cardiomyopathy (Takutsubo cardiomyopathy), the ECG and cardiac biomarker changes with acute brain injury, and the heightened cardiovascular risk associated with depression, post-traumatic stress disorder and other mental health problems. (frontiersin.org)
  • The recent availability of wireless mobile health (mHealth) devices for the continuous, non-obtrusive, passive monitoring, and transmission of numerous biometric parameters allows, for the first time, a more comprehensive and detailed evaluation of the acute neurological and cardiovascular responses to meditation. (frontiersin.org)
  • All of these systems are vital for health and life. (scai.org)
  • The fourth edition of The Cardiovascular System at a Glance is an ideal resource for medical students, whilst students of other health professions and specialist cardiology nurses will also find it invaluable. (wiley.com)
  • Fetal, early childhood, and adolescent environmental exposures can impair cardiovascular health and function. (aappublications.org)
  • In addition, biological and lifestyle factors can strongly affect cardiovascular health, sometimes by interacting with the effects of environmental exposures. (aappublications.org)
  • Methodist Health System believes its greatest asset is the team members in our organization that values and encourages diversity and inclusion in all aspects of our organization. (healthcaresource.com)
  • Leader in women's cardiovascular health honored. (ucdavis.edu)
  • UC Davis Health System is advancing the health of patients everywhere by providing excellent patient care, conducting groundbreaking research, fostering innovative, interprofessional education, and creating dynamic, productive partnerships with the community. (ucdavis.edu)
  • The academic health system includes one of the country's best medical schools, a 645-bed acute-care teaching hospital, an 800-member physician's practice group and the new Betty Irene Moore School of Nursing. (ucdavis.edu)
  • Our ultimate goal is to further accelerate developments in the rapidly expanding field of cardiovascular systems medicine, with the overall aim of improving cardiovascular health in both patients and healthy individuals. (frontiersin.org)
  • Iron can have detrimental effect on the health system if it chronically accumulates over a long period of time like in patients who need chronic blood transfusions or in patients born with an in-born error of iron metabolism called hemochromatosis. (doctorslounge.com)
  • A new approach to learning anatomy: Use your favorite ebook device and learn the most relevant anatomical structures of the The cardiovascular System on the go. (apple.com)
  • Major players in the cardiovascular information systems market include Philips Healthcare (Netherlands), McKesson Corporation (U.S.), GE Healthcare (U.K.), Siemens Healthcare (Germany), Merge Healthcare (U.S.), Lumedx (U.S.), Agfa Healthcare (Belgium), Fujifilm Medical Systems (Japan), Digisonics (U.S.), and Cerner Corporation (U.S. (pitchengine.com)
  • Further research is required to determine the full extent to which testosterone replacement therapy in aging men plays a role in the risk and/or advantage of cardiovascular occurrences. (wikipedia.org)
  • This test is often included in cardiovascular testing as an indicator of future risk of cardiovascular problems. (mcssl.com)
  • Furthermore, chronic disruptions of the circadian clock, as with night-shift work, contribute to increased cardiovascular risk. (jci.org)
  • Traditional cardiovascular risk factors and inflammatory markers (hsCRP, IL-6, TNF α , adiponectin) were studied together with IMT (intima-media thickness), FMD (flow mediated dilation), and LVMi (left ventricle mass index) as surrogate markers of subclinical atherosclerosis. (hindawi.com)
  • however, previous studies have mostly assessed the effect of cardiovascular risk factors on quality of life. (cdc.gov)
  • Data were from the 2013 Behavioral Risk Factor Surveillance System, a state-based telephone survey of adults 18 years or older (N = 347,073). (cdc.gov)
  • Antihypertensive drug classes and the risk of hip fracture: results from the Swedish primary care cardiovascular database. (gu.se)
  • Exposure to cancer chemotherapy or radiotherapy in childhood raises the risk of long-term progressive left ventricular dysfunction and other cardiovascular problems. (aappublications.org)
  • Building a Fully Integrated Cardiovascular Imaging and Information System" is essential viewing for heart centers looking for hands-on knowledge and field-tested experience in developing a successful, highly productive, fully integrated CVIS. (redorbit.com)
  • Building a Fully Integrated Cardiovascular Imaging and Information System" is part of the Success In CVIS Webinar Series, sponsored by LUMEDX Corporation (http://www.lumedx.com/), a leading provider of fully integrated cardiovascular imaging and information solutions. (redorbit.com)
  • On the basis of system type, the cardiovascular information system market is segmented into CVIS and CPACS. (pitchengine.com)
  • The CVIS segment is expected to account for the largest share of the global cardiovascular information system market in 2015. (pitchengine.com)
  • On the basis of type, the cardiovascular information systems market is segmented into CVIS and C-PACS. (marketsandmarkets.com)
  • It provides value information for the various types of CVIS solutions, components, modes of operation, and applications of cardiovascular information systems. (marketsandmarkets.com)
  • The Texas Heart Institute has noted that performing routine cardiovascular exercise affects the entire cardiovascular system. (ehow.co.uk)
  • Blood travels through your entire cardiovascular system. (scai.org)
  • Synapse Cardiovascular provides echo labs with one-click measurement tools, pre-configured and customizable report templates, and wall motion scoring intelligence to reduce read and report time. (fujifilmusa.com)
  • More than 400-ASE default cardiac measurements and calculations are available for on- or off-line analysis, and data from acquisition devices can be transferred to Synapse Cardiovascular to automatically populate reports. (fujifilmusa.com)
  • With a diagram-driven graphical user interface, intuitive report preparation functions and advanced image evaluation tools, Synapse Cardiovascular helps to boost cath lab productivity and accuracy. (fujifilmusa.com)
  • Seeing as the cardiovascular organs are the heart and blood vessels, if that is what you meant. (answers.com)
  • The cardiovascular system (the heart and blood vessels) is the most vitally important organ system in the body. (answersingenesis.org)
  • Greetings, so today we wanted to start a discussion about the cardiovascular system, and in particular we're going to talk about the heart and the structure of the heart, and how the heart activities are coordinated by an electrical conduction system. (coursera.org)
  • What we want to talk about is the conduction system of the heart, which are specialized cardiac miocytes. (coursera.org)
  • Secondly we want to talk about this pacemaker activity, because, as you all know, the heart has an intrinsic beat, and that's due to these pacemaker cells or this electrical conduction system. (coursera.org)
  • In which choice are the components of the cardiac conduction system listed in the correct order in which they conduct the cardiac impulse? (flashcardmachine.com)
  • The cardiac muscle is self-exciting, meaning it has its own conduction system. (wikibooks.org)
  • Among the cardiovascular problems that may be caused by environmental exposures are abnormal anatomic development, dysrhythmias, conduction system defects, myocardial abnormalities, and derangements in blood pressure and cholesterol metabolism. (aappublications.org)
  • The global cardiovascular information system market report begins with an overview of cardiovascular information systems and key market definitions. (bccresearch.com)
  • Endogenous, approximately 24-hour circadian rhythms in the brain, autonomic nervous system, heart, and vasculature prepare the cardiovascular system for optimal function during these anticipated behavioral cycles. (jci.org)
  • Fibromyalgia itself interferes with the regulation of the autonomic nervous system that controls heart rate. (fibromyalgia-symptoms.org)
  • The cardiovascular system effects the circulation of blood around the body, which brings about transport of nutrients and oxygen to the tissues and the removal of waste products. (encyclopedia.com)
  • The cardiovascular system consists of the heart, blood vessels, and the approximately 5 liters of blood that the blood vessels transport. (innerbody.com)
  • The spleen produces blood cells, and forms part of the immune system. (answers.com)
  • 8. A high-frequency intra-arterial cardiac support system according to claim 5 in which said valve is a collapsible one-way passive check valve oriented to direct blood flow predominantly in the direction of normal blood flow away from the natural heart. (freepatentsonline.com)
  • Side-effects include nervousness, insomnia, increased motor activity and cardiovascular disturbances such as tachycardia and elevation of blood pressure. (clinicaltrials.gov)
  • In contrast to the blood vascular circulation, the lymphatic system forms a unidirectional transit pathway from the extracellular space to the venous system. (nih.gov)
  • Everything from your breathing and blood pressure levels to blood flow and energy levels can get out of whack if your cardiovascular system isn�t working properly. (fibromyalgia-symptoms.org)
  • The cardiovascular system distributes blood throughout your body. (scai.org)
  • To understand the cardiovascular system, we can follow the path of blood, beginning in the heart. (scai.org)
  • If we do find that melatonin is able to lower heart rate and blood pressure throughout the night, this would be a very positive finding indicating that the use of melatonin could potentially provide long-term benefits to the cardiovascular system. (healthy.net)
  • The cardiovascular system consists of the heart located centrally in the thorax and the vessels of the body which transport blood. (indigo.ca)
  • Dr. Nagelkirk will discuss how hemostatic systems prevent blood loss in the case of injury, how those same systems contribute to adverse events (i.e., heart attack and stroke), as well as how acute exercise and regular physical activity modulate blood clotting potential. (acsm.org)
  • The cardiovascular system consists of the heart, blood vessels, and blood. (cliffsnotes.com)
  • The cardiovascular system protects the body through its white blood cells. (nationwidepharmacies.co.uk)
  • The SphygmoCor Cardiovascular Management System (CVMS) is a lightweight, portable device used to non-invasively obtain important vital cardiovascular data that cannot be obtained with traditional brachial cuff blood pressure measurements. (medicalsearch.com.au)
  • Central blood pressure, measured with the SphygmoCor CP system, has been shown to be a superior predictor of cardiovascular events, when compared to brachial pressure. (medicalsearch.com.au)
  • SphygmoCor Pulse Wave analysis software and the SphygmoCor CP system, are the global gold standard for central blood pressure and arterial stiffness assessment. (medicalsearch.com.au)
  • Persistence Market Research examines the performance of the global cardiovascular information system market for a period of eight years in a new report titled "Cardiovascular Information System Market: Global Industry Analysis and Forecast, 2016-2024. (bccresearch.com)
  • According to the report, key players in the global cardiovascular information system market are focusing on the development of new solutions that can solve interoperability issues faced by healthcare settings. (bccresearch.com)
  • This Persistence Market Research report examines the global cardiovascular information system market for the period 2016-2024. (bccresearch.com)
  • The primary objective of the report is to offer insights into developments in the global cardiovascular information system market that are effecting the global businesses and enterprises. (bccresearch.com)
  • This report covers the global cardiovascular information system market performance in terms of revenue contribution from various segments. (bccresearch.com)
  • The report also includes Persistence Market Research's analysis of key trends, drivers, restraints and opportunities, which are influencing the growth of the global cardiovascular information system market. (bccresearch.com)
  • This section also underlines factors influencing the growth of the global cardiovascular information system market along with a detailing of the key trends, drivers, restraints, and opportunities. (bccresearch.com)
  • The next section of the report highlights the region wise growth trends of the global cardiovascular information system market. (bccresearch.com)
  • It provides a market outlook for 2015-2024 and sets the forecast within the context of the global cardiovascular information system market. (bccresearch.com)
  • In the final section of the report on the global cardiovascular information system market, a 'Competitive Landscape' is included to provide report audiences with a dashboard view to access the key differentiators among the various competitor firms. (bccresearch.com)
  • Detailed company profiles presented in this section include company-specific long-term and short-term strategies, key offerings and recent developments in the global cardiovascular information system market. (bccresearch.com)
  • To offer an accurate forecast for the market numbers, the report starts by sizing up the current market, which forms the basis of how the global cardiovascular information system market is expected to develop in the future. (bccresearch.com)
  • This report provides insights on the global cardiovascular information system market. (marketsandmarkets.com)
  • Your cardiovascular system pumps and delivers crucial oxygen and nutrients to your entire body. (livestrong.com)
  • In mammalian cells, 3 distinct isoforms of Akt exist, but their precise roles in cardiovascular biology were previously unknown. (jci.org)
  • Normal cardiovascular function requires the concerted action of many cell types, each capable of adaptive gene expression in response to developmental, physiological, and pathological cues. (cshlpress.com)
  • In this paper we investigate a possibility of using virtual instrumentation in the development of two physiological parameters monitoring system, in order to assess a cardiovascular parameter, the Pulse Wave Velocity (PWV). (embedded.com)
  • In this module you will learn how a number of key physiological systems (muscular, respiratory, cardiovascular, endocrine and immune systems) are regulated during exercise to help maintain homeostasis. (coursera.org)
  • The Cardiovascular System: Design, Control and Function, Volume 36A, a two- volume set, not only provides comprehensive coverage of the current knowledge in this very active and growing field of research, but also highlights the diversity in cardiovascular morphology and function and the anatomical and physiological plasticity shown by fish taxa that are faced with various abiotic and biotic challenges. (researchandmarkets.com)
  • FDA approval of our Diamondback 360 Coronary OAS allows us to bring to market the first new coronary atherectomy system in more than two decades. (businesswire.com)
  • The coronary system is limited by federal law to investigational use and is currently not commercially available in the United States. (aol.com)
  • In this paper, we focus on the effect of energy drinks on the cardiovascular system and whether the current ongoing call for the products' sales and regulation of their contents should continue. (nih.gov)
  • Knowing the functions of the cardiovascular system and the parts of the body that are part of it is critical in understanding the physiology of the human body. (cliffsnotes.com)
  • For instance, according to the American Journal of Heart, in the Veterans Administration Healthcare System (U.S.), the number of echocardiograms increased by 112.2% from 2000 to 2007. (sbwire.com)
  • The South Broward Hospital District Board of Commissioners, which oversees all actions of Memorial Healthcare System, elected its officers at the recent July board meeting. (mhs.net)
  • The Board of Commissioners of the South Broward Hospital District, which oversees the operations for Memorial Healthcare System, voted on a new millage rate during its September board meeting. (mhs.net)
  • In addition, stable kinin agonists may also be available in the future astherapeutic agents for cardiovascular and renal disorders. (hindawi.com)
  • The current and future shortage of pediatric cardiologists necessitates information on the pediatric heart for primary care clinicians, as they care for the child and adolescent with cardiovascular dilemmas and disorders. (novapublishers.com)
  • The company's patented bleed monitoring system for vascular access procedures enables physicians to mitigate downstream consequences by addressing bleeding complications immediately, improving patient outcomes and lowering healthcare costs. (businesswire.com)
  • Drawing from a wide range of patient care experiences, a broad-based curriculum incorporates the latest advances in preventive cardiology and cardiovascular medicine. (christianacare.org)
  • Cardiovascular Systems expects full-year revenue in the range of $240 million to $250 million. (yahoo.com)
  • In connection with the offering, Cardiovascular Systems (CSI) expects to grant underwriters a 30-day option to purchase up to an additional 15% of the shares being offered as well. (massdevice.com)
  • We aimed to determine the prevalence of excess body mass in juvenile idiopathic arthritis (JIA) children and to investigate the influence of obesity into the early, subclinical changes in cardiovascular system in these patients. (hindawi.com)
  • Coincident obesity is common in JIA children and is associated with insulin resistance, dyslipidemia, and increased levels of inflammatory markers leading to early changes in cardiovascular system. (hindawi.com)
  • It is part of the lymphatic system, not the cardiovascular system. (answers.com)
  • The spleen is part of the lymphatic system. (answers.com)
  • The spleen is a functional part of the Circulation System. (answers.com)
  • The heart is where circulation and cooperation between the respiratory and the cardiovascular systems begin. (ehow.co.uk)
  • These concepts seem so obvious that it is hard to imagine that the enthronement of the nervous system is not "natural. (encyclopedia.com)
  • The Cardiovascular System Center in HealthWorld Online provides information on self-care as well as alternative approaches to prevention and treatment of Cardiovascular System through expert articles from leaders in the fields of complementary and alternative medicine (CAM), including Acupuncture and Chinese Medicine, Ayurveda, Homeopathy, Naturopathy, Osteopathy, Herbal Medicine, Mind-Body Medicine, and Integrative Medicine. (healthy.net)
  • Amparo Villablanca, a pioneer, leader and recognized expert in women's cardiovascular medicine, has been selected as a recipient of the 2011 Distinguished Scholarly Public Service Award by the Public Service Committee of the Davis Division of the Academic Senate of the University of California. (ucdavis.edu)
  • The section Cardiovascular Genetics and Systems Medicine concentrates on papers covering a range of topics in all aspects of cardiovascular genetics with a special emphasis on systems medicine approaches. (frontiersin.org)
  • Recognizing these challenges, the editors of Cardiovascular Genetics and Systems Medicine encourage genetic and systems-oriented cardiovascular research that would lead to improved prevention, more comprehensive diagnostics and individually adjusted therapy schemes in precision medicine. (frontiersin.org)
  • All manuscripts must be submitted directly to the section Cardiovascular Genetics and Systems Medicine, where they are peer-reviewed by the Associate and Review Editors of the specialty section. (frontiersin.org)
  • Articles published in the section Cardiovascular Genetics and Systems Medicine will benefit from the Frontiers impact and tiering system after online publication. (frontiersin.org)
  • The system further comprises a control and drive mechanism for providing cyclical fluid flow to the lumen of the catheter for inflation and deflation of the pumping balloon. (freepatentsonline.com)
  • In case reports, acute myocardial infarction is the most common event presented, but other adverse cardiovascular effects such as left ventricular hypertrophy, reduced left ventricular function, arterial thrombosis, pulmonary embolism and several cases of sudden cardiac death have also been reported. (nih.gov)
  • Distinguishing features of the report include integrating cath labs to cardiovascular information systems, Meaningful Use incentives and a wide range of functionalities. (bccresearch.com)
  • The SphygmoCor CPV system includes Pulse Wave Velocity software, as well as the Pulse Wave analysis software supplied on the SphygmoCor CP. (medicalsearch.com.au)
  • The SphygmoCor CPV system is the global standard for pulse wave velocity assessment, and has been the used in hundreds of published studies. (medicalsearch.com.au)
  • In addition to Pulse Wave Velocity, and Pulse Wave Analysis software, the SphygmoCor CPVH system also provides Heart Rate Variability software. (medicalsearch.com.au)
  • Philips reported a vulnerability in the Philips' IntelliSpace Cardiovascular and Xcelera cardiac image and information management systems. (us-cert.gov)
  • The Philips IntelliSpace Cardiovascular and Xcelera systems (a predecessor to IntelliSpace Cardiovascular) are comprehensive cardiac image and information management software. (us-cert.gov)
  • Philips has initiated a voluntary medical device correction aligned with IntelliSpace Cardiovascular proactive field change order (reference FCO83000202) to be issued as IntelliSpace Cardiovascular updates become available. (us-cert.gov)
  • Users with questions regarding their specific IntelliSpace Cardiovascular or Xcelera installations are advised by Philips to contact their local Philips service support team or their regional service support. (us-cert.gov)
  • Boston Scientific to Collaborate with Philips and Siemens on Cardiovascular Imaging Technology. (highbeam.com)
  • Ik wil marketing gerelateerde digitale communicatie ontvangen over Philips producten, diensten, evenementen en aanbiedingen die voor mij relevant kunnen zijn gezien mijn gebruikersvoorkeuren en -gedrag. (philips.nl)
  • For example, cause for concern about the role of the environment in the development of congenital cardiovascular malformations is found in the fact that such malformations are associated with exposure to maternal human immunodeficiency virus (HIV) infection, regardless of whether the child is infected. (aappublications.org)
  • The article Taking Stock of Cardiovascular Systems originally appeared on Fool.com. (aol.com)
  • The article Cardiovascular Systems Inc is Crashing Today: Here's Why originally appeared on Fool.com. (foxbusiness.com)
  • The normal amplified responses in the morning may aid the transition from sleep to activity, but such exaggerated responses are potentially perilous in individuals susceptible to adverse cardiovascular events. (jci.org)