A change in cardiovascular function resulting in a reduction in BLOOD VOLUME, and reflex DIURESIS. It occurs frequently after actual or simulated WEIGHTLESSNESS.
Posture while lying with the head lower than the rest of the body. Extended time in this position is associated with temporary physiologic disturbances.
Condition under normal Earth gravity where the force of gravity itself is not actually altered but its influence or effect may be modified and studied. (From ASGSB Bull 1992;5(2):27)
Confinement of an individual to bed for therapeutic or experimental reasons.
External decompression applied to the lower body. It is used to study orthostatic intolerance and the effects of gravitation and acceleration, to produce simulated hemorrhage in physiologic research, to assess cardiovascular function, and to reduce abdominal stress during childbirth.
Techniques and routines designed to prevent or reverse unwanted effects of weightlessness experienced during actual and simulated space flight, including physiologic changes related to removal of gravitational loading. Specific measures include creation of artificial gravity, exercise, low-level lower body negative pressure, and use of anti-deconditioning devices. (From Nicogossian, Space Physiology and Medicine, 2d ed, pp294-297)
Symptoms of cerebral hypoperfusion or autonomic overaction which develop while the subject is standing, but are relieved on recumbency. Types of this include NEUROCARDIOGENIC SYNCOPE; POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME; and neurogenic ORTHOSTATIC HYPOTENSION. (From Noseworthy, JH., Neurological Therapeutics Principles and Practice, 2007, p2575-2576)

A 30-year follow-up of the Dallas Bedrest and Training Study: II. Effect of age on cardiovascular adaptation to exercise training. (1/28)

BACKGROUND: Aerobic power declines with age. The degree to which this decline is reversible remains unclear. In a 30-year longitudinal follow-up study, the cardiovascular adaptations to exercise training in 5 middle-aged men previously trained in 1966 were evaluated to assess the degree to which the age-associated decline in aerobic power is attributable to deconditioning and to gain insight into the specific mechanisms involved. Methods and Results-- The cardiovascular response to acute submaximal and maximal exercise were assessed before and after a 6-month endurance training program. On average, VO(2max) increased 14% (2.9 versus 3.3 L/min), achieving the level observed at the baseline evaluations 30 years before. Likewise, VO(2max) increased 16% when indexed to total body mass (31 versus 36 mL/kg per minute) or fat-free mass (44 versus 51 mL/kg fat-free mass per minute). Maximal heart rate declined (181 versus 171 beats/min) and maximal stroke volume increased (121 versus 129 mL) after training, with no change in maximal cardiac output (21.4 versus 21.7 L/min); submaximal heart rates also declined to a similar degree. Maximal AVDO(2) increased by 10% (13.8 versus 15.2 vol%) and accounted for the entire improvement of aerobic power associated with training. CONCLUSIONS: One hundred percent of the age-related decline in aerobic power among these 5 middle-aged men occurring over 30 years was reversed by a 6-month endurance training program. However, no subject achieved the same maximal VO(2) attained after training 30 years earlier, despite a similar relative training load. The improved aerobic power after training was primarily the result of peripheral adaptation, with no effective improvement in maximal oxygen delivery.  (+info)

Remodeling of left ventricular hypertrophy in elite athletes after long-term deconditioning. (2/28)

BACKGROUND: The clinical significance and long-term consequences of left ventricular (LV) hypertrophy associated with intensive athletic conditioning remain unresolved. METHODS AND RESULTS: We prospectively evaluated 40 elite male athletes who had shown marked LV cavity enlargement of > or = 60 mm, wall thickness of > or = 13 mm, or both in a longitudinal fashion with serial echocardiograms, initially at peak training (age 24 +/- 4 years) and subsequently after a long-term deconditioning period (1 to 13 years; mean, 5.6 +/- 3.8). After detraining, LV cavity dimension decreased by 7% (61.2 +/- 2.9 to 57.2 +/- 3.1 mm; P<0.001), maximum wall thickness by 15% (12.0 +/- 1.3 to 10.1 +/- 0.8 mm; P<0.001), and mass normalized to height by 28% (194 +/- 25 to 140 +/- 21 g/m; P<0.001). However, individual subject analysis showed persistent substantial cavity dilatation (> or = 60 mm) in 9 athletes (22%); in contrast, wall thickness returned to normal in each athlete. Multiple regression analysis demonstrated that approximately 50% of the incomplete reduction in cavity dimension was explained by increased body weight and recreational physical activity performed during the follow-up period. No athlete had developed cardiac symptoms, impaired exercise performance, or evidence of LV dysfunction. CONCLUSIONS: LV remodeling was evident after long-term detraining, with significant reduction in cavity size and normalization of wall thickness. Resolution of cavity enlargement was, however, incomplete in most cases, and substantial chamber dilatation persisted in >20% of athletes. The possibility that this residual LV hypertrophy, apparently part of the athlete's heart syndrome, may have future long-term clinical implications in some individuals cannot be excluded with certainty.  (+info)

Deconditioning fails to explain peripheral skeletal muscle alterations in men with chronic heart failure. (3/28)

It remains controversial whether the skeletal muscle alterations in chronic heart failure (CHF) are due to disease pathophysiology or result from chronic deconditioning. The purpose of this study was to compare the skeletal muscle of CHF patients to peak oxygen consumption (peak VO(2)) matched sedentary controls. It has been established that skeletal muscle abnormalities are related to the exercise intolerance observed in patients with CHF. We studied the skeletal muscle of sedentary controls and patients with CHF matched for age, gender and peak VO(2). Hypothesis testing for the effects of group (CHF vs. normal), gender, and the interaction group x gender were performed. For capillary density only gender (p = 0.002) and the interaction of group x gender (p = 0.007) were significantly different. For 3-hydroxyl coenzyme A (CoA) dehydrogenase only group effect (p = 0.004) was significantly different. Mean values for capillary density were 1.46 +/- 0.28 for CHF men versus 1.87 +/- 0.32 for sedentary control men, 1.40 +/- 0.32 for CHF women versus 1.15 +/- 0.35 for sedentary control women. The activities for 3-hydroxyl CoA dehydrogenase were 3.09 +/- 0.88 for CHF men versus 4.05 +/- 0.42 for sedentary control men, 2.93 +/- 0.72 for CHF women versus 3.51 +/- 0.78 for sedentary control women. This study suggests that women and men adapt to CHF differently: men develop peripheral skeletal muscle abnormalities that are not attributable to deconditioning; women do not develop the same pathologic responses in skeletal muscle when compared with normal women matched for aerobic capacity.  (+info)

Impact of physical deconditioning on ventricular tachyarrhythmias in trained athletes. (4/28)

OBJECTIVES: The purpose of this research was to evaluate the impact of athletic training and, in particular, physical deconditioning, on frequent and/or complex ventricular tachyarrhythmias assessed by 24-h ambulatory (Holter) electrocardiogram (ECG). BACKGROUND: Sudden deaths in athletes are usually mediated by ventricular tachyarrhythmias. METHODS: Twenty-four hour ambulatory ECGs were recorded at peak training and after a deconditioning period of 19 +/- 6 weeks (range, 12 to 24 weeks) in a population of 70 trained athletes selected on the basis of frequent and/or complex ventricular tachyarrhythmias (i.e., > or =2,000 premature ventricular depolarization [PVD] and/or > or =1 burst of non-sustained ventricular tachycardia [NSVT]/24 h). RESULTS: A significant decrease in the frequency and complexity of ventricular arrhythmias was evident after deconditioning: PVDs/24 h: 10,611 +/- 10,078 to 2,165 +/- 4,877 (80% reduction; p < 0.001) and NSVT/24 h: 6 +/- 22 to 0.5 +/- 2, (90% reduction; p = 0.04). In 50 of the 70 athletes (71%), ventricular arrhythmias decreased substantially after detraining (to <500 PVDs/24 h and no NSVT). Most of these athletes with reduced arrhythmias did not have structural cardiovascular abnormalities (37 of 50; 74%). Over the 8 +/- 4-year follow-up period, each of the 70 athletes survived without cardiac symptoms. CONCLUSIONS: Frequent and/or complex ventricular tachyarrhythmias in trained athletes (with and without cardiovascular abnormalities) are sensitive to brief periods of deconditioning. In athletes with heart disease, the resolution of such arrhythmias with detraining may represent a mechanism by which risk for sudden death is reduced. Conversely, in athletes without cardiovascular abnormalities, reduction in frequency of ventricular tachyarrhythmias and the absence of cardiac events in the follow-up support the benign clinical nature of these rhythm disturbances as another expression of athlete's heart.  (+info)

Effects of exercise training and deconditioning on platelet aggregation induced by alternating shear stress in men. (5/28)

OBJECTIVE: Alternating shear stress, which resembles the flow condition in stenotic arteries, induces platelet aggregation. This study investigated how exercise training and deconditioning influence alternating shear-induced platelet aggregation (ASIPA) and clarify the mechanisms underlying ASIPA. METHODS AND RESULTS: Thirty healthy male sedentary subjects were randomly divided into control and trained groups. The trained men were trained on a bicycle ergometer at approximately 60% of maximal oxygen consumption for 30 minutes per day, 5 days per week for 8 weeks, and then were deconditioned for 8 weeks. The experimental results indicate the following: (1) short-term strenuous exercise increases the extent of ASIPA and is accompanied by increased the von Willebrand factor (vWF) binding and P-selectin expression on platelets in both the control and trained groups, whereas the enhancement of platelet function decreases after exercise training in trained subjects; (2) at rest and immediately after exercise, ASIPA and the vWF binding and P-selectin expression on platelets are reduced by training, but remain unchanged in the control group; and (3) deconditioning reverses the effects of training on resting and postexercise state. CONCLUSIONS: Exercise training suppresses the extent of ASIPA, probably by reducing vWF binding to platelets and P-selectin expression on platelets. However, deconditioning reverses the training effects. This investigation shows that exercise training decreases resting and severe exercise-promoted platelet aggregation induced by alternating shear stress (ASIPA); moreover, this effect is accompanied by reduced the von Willebrand factor binding and P-selectin expression on platelets. However, the effects of training on ASIPA are reversed to the pretraining state after deconditioning.  (+info)

Exercise training and 3-day head down bed rest deconditioning: exercise thermoregulation. (6/28)

Bed rest (BR) deconditioning causes excessive increase of exercise core body tempera-ture, while aerobic training improves exercise thermoregulation. The study was designed to determine whether 3 days of 6 degrees head-down bed rest (HDBR) affects body temperature and sweating dynamics during exercise and, if so, whether endurance training before HDBR modifies these responses. Twelve healthy men (20.7+/-0.9 yrs, VO2max: 46+/-4 ml x kg(-1) x min(-1) ) underwent HDBR twice: before and after 6 weeks of endurance training. Before and after HDBR, the subjects performed 45 min sitting cycle exercise at the same workload equal to 60% of VO2max determined before training. During exercise the VO2, HR, tympanic (Ttymp) and skin (Tsk) temperatures were recorded; sweating dynamics was assayed from a ventilated capsule on chest. Training increased VO2max by 12.1% (p<0.001). Resting Ttymp increased only after first HDBR (by 0.22 +/- 0.08 degrees C, p<0.05), while exercise equilibrium levels of Ttymp were increased (p<0.05) by 0.21 +/- 0.07 and 0.26 +/- 0.08 degrees C after first and second HDBR, respectively. Exercise mean Tsk tended to be lower after both HDBR periods. Total sweat loss and time-course of sweating responses were similar in all exercise tests. The sweating threshold related to Ttymp was elevated (p<0.05) only after first HDBR. IN CONCLUSION: six-week training regimen prevents HDBR-induced elevation of core temperature (Ttymp) at rest but not during ex-ercise. The post-HDBR increases of Ttymp without changes in sweating rate and the tendency for lower Tsk suggest an early (<3d) influence of BR on skin blood flow.  (+info)

Altered hormonal regulation and blood flow distribution with cardiovascular deconditioning after short-duration head down bed rest. (7/28)

This study tested the hypothesis that cardiovascular and hormonal responses to lower body negative pressure (LBNP) would be altered by 4-h head down bed rest (HDBR) in 11 healthy young men. In post-HDBR testing, three subjects failed to finish the protocol due to presyncopal symptoms, heart rate was increased during LBNP compared with pre-HDBR, mean arterial blood pressure was elevated at 0, -10, and -20 mmHg and reduced at -40 mmHg, central venous pressure (CVP) and cardiac stroke volume were reduced at all levels of LBNP. Plasma concentrations of renin, angiotensin II, and aldosterone were significantly lower after HDBR. Renin and angiotensin II increased in response to LBNP only post-HDBR. There was no effect of HDBR or LBNP on norepinephrine while epinephrine tended to increase at -40 mmHg post-HDBR (P = 0.07). Total blood volume was not significantly reduced. Splanchnic blood flow taken from ultrasound measurement of the portal vein was higher at each level of LBNP post-compared with pre-HDBR. The gain of the cardiopulmonary baroreflex relating changes in total peripheral resistance to CVP was increased after HDBR, but splanchnic vascular resistance was actually reduced. These results are consistent with our hypothesis and suggest that cardiovascular instability following only 4-h HDBR might be related to altered hormonal and/or neural control of regional vascular resistance. Impaired ability to distribute blood away from the splanchnic region was associated with reduced stroke volume, elevated heart rate, and the inability to protect mean arterial pressure.  (+info)

Does long-term experimental antiorthostasis lead to cardiovascular deconditioning in the rat? (8/28)

Microgravity or simulated microgravity induces acute and chronic cardiovascular responses, whose mechanism is pivotal for understanding of physiological adaptation and pathophysiological consequences. We investigated hemodynamic responses of conscious Wistar rats to 45? head-down tilt (HDT) for 7 days. Arterial blood pressure (BP) was recorded by telemetry. Heart rate (HR), spectral properties and the spontaneous baroreflex sensitivity (sBRS) were calculated. Head-up tilt (HUT) was applied for 2 h before and after HDT to assess the degree of any possible cardiovascular deconditioning. Horizontal control BP and HR were 112.5+/-2.8 mmHg and 344.7+/-10 bpm, respectively. HDT elicited an elevation in BP and HR by 8.3 % and 8.8 %, respectively, in less than 1 h. These elevations in BP and HR were maintained for 2 and 3 days, respectively, and then normalized. Heart rate variability was unchanged, while sBRS was permanently reduced from the beginning of HDT (1.01+/-0.08 vs. 0.74+/-0.05 ms/mmHg). HUT tests before and after HDT resulted in BP elevations (6.9 vs. 11.6 %) and sBRS reduction (0.44 vs. 0.37 ms/mmHg), respectively. The pressor response during the post-HDT HUT test was accompanied by tachycardia (13.7 %). In conclusion, chronic HDT does not lead to symptoms of cardiovascular deconditioning. However the depressed sBRS and tachycardic response seen during the post-HDT HUT test may indicate disturbances in cardiovascular control.  (+info)

Cardiovascular deconditioning is a condition that results from a decrease in the body's ability to adapt to physical stress due to a lack of regular physical activity and exercise. This leads to changes in the cardiovascular system, including reduced blood volume, stroke volume, and maximal oxygen uptake (VO2 max), as well as increased heart rate and systolic blood pressure during exercise.

Physical deconditioning can occur in individuals who are bedridden, sedentary, or have undergone prolonged periods of inactivity due to illness, injury, or other factors. It is also a concern for astronauts who experience reduced physical activity and muscle atrophy during spaceflight.

Cardiovascular deconditioning can lead to decreased exercise tolerance, fatigue, shortness of breath, and an increased risk of cardiovascular disease. Regular exercise and physical activity are essential for maintaining cardiovascular fitness and preventing deconditioning.

Head-down tilt (HDT) is a positioning technique often used in medical settings, particularly during diagnostic procedures or treatment interventions. In this position, the person lies down on a specially designed table with their head tilted below the horizontal plane, typically at an angle of 6 degrees to 15 degrees, but sometimes as steep as 90 degrees. This posture allows for various medical evaluations such as carotid sinus massage or intracranial pressure monitoring. It is also used in space medicine to simulate some effects of weightlessness on the human body during spaceflight. Please note that prolonged exposure to head-down tilt can have physiological consequences, including changes in blood pressure, heart rate, and eye function, which should be monitored and managed by healthcare professionals.

Weightlessness simulation, also known as "zero-gravity" or "microgravity" simulation, is the reproduction of the condition in which people or objects appear to be weightless. This state can be achieved through various methods, including neutral buoyancy, which is simulating the feeling of weightlessness by immersing individuals in a fluid (usually water) with a density equal to their body, or reduced-gravity environments created using specialized equipment such as aircraft that fly in parabolic arcs to generate brief periods of weightlessness.

Another method for weightlessness simulation is through the use of virtual reality and other technology to create an illusion of weightlessness. This can be done by manipulating visual and auditory cues, as well as providing a haptic feedback system that simulates the sensation of movement in zero-gravity environments. These simulations are often used for training astronauts, researching the effects of weightlessness on the human body, and developing technologies for use in space.

Bed rest is a medical recommendation for a person to limit their activities and remain in bed for a period of time. It is often ordered by healthcare providers to help the body recover from certain medical conditions or treatments, such as:

* Infections
* Pregnancy complications
* Recent surgery
* Heart problems
* Blood pressure fluctuations
* Bleeding
* Bone fractures
* Certain neurological conditions

The duration of bed rest can vary depending on the individual's medical condition and response to treatment. While on bed rest, patients are typically advised to change positions frequently to prevent complications such as bedsores, blood clots, and muscle weakness. They may also receive physical therapy, occupational therapy, or other treatments to help maintain their strength and mobility during this period.

Lower Body Negative Pressure (LBNP) is a medical term that refers to the application of a negative pressure (below atmospheric pressure) to the lower body, while the upper body remains at normal atmospheric pressure. This is typically achieved through the use of an air-tight chamber or suit that covers the lower body from the waist down.

The negative pressure causes fluid to be drawn towards the lower body, which can simulate the effects of weightlessness or reduced gravity on the cardiovascular system. LBNP is often used in research settings to study the physiological responses to changes in gravitational forces, as well as in clinical settings to help prevent or treat various medical conditions, such as orthostatic intolerance, venous ulcers, and chronic wounds.

Weightlessness countermeasures refer to the methods and techniques used to prevent or minimize the negative effects of weightlessness (or microgravity) on the human body during spaceflight. Prolonged exposure to weightlessness can lead to various physiological changes, such as muscle atrophy, bone loss, cardiovascular deconditioning, and balance disorders. Weightlessness countermeasures aim to mitigate these effects through various strategies, including:

1. Exercise: Regular exercise, particularly resistance and aerobic exercises, helps maintain muscle strength, endurance, and cardiovascular fitness during spaceflight. Devices like the Advanced Resistive Exercise Device (ARED) and treadmills are used on the International Space Station (ISS) to provide a suitable exercise routine for astronauts.
2. Nutrition: Adequate nutrient intake, including calcium, vitamin D, and protein, is essential for maintaining bone and muscle health during spaceflight. Monitoring and optimizing dietary habits can help counteract the negative effects of weightlessness on the body.
3. Medications and supplements: Some medications and supplements may be used to prevent or treat specific issues related to weightlessness, such as bone loss (bisphosphonates) or muscle wasting (anabolic agents). However, these interventions should be carefully evaluated for their risks and benefits.
4. Artificial gravity: Systems that create a gravitational force, such as rotating spacecraft or centrifuges, can help maintain the body's physiological adaptations to Earth's gravity. Although not yet implemented in human spaceflight, artificial gravity is a promising countermeasure for long-duration missions.
5. Pre- and post-flight rehabilitation: A well-structured rehabilitation program before and after spaceflight can help astronauts recover more quickly from the effects of weightlessness and reduce the risk of long-term health issues.
6. Monitoring and telemedicine: Regular monitoring of physiological parameters, such as muscle mass, bone density, and cardiovascular function, allows for early detection and intervention of any adverse effects related to weightlessness. Telemedicine can also provide remote medical support and guidance during space missions.

Overall, a comprehensive approach that combines various countermeasures is essential for minimizing the negative impacts of weightlessness on astronaut health during and after space missions.

Orthostatic intolerance is a condition in which an individual experiences lightheadedness, dizziness, or fainting when standing or maintaining an upright position for extended periods. It is caused by an abnormal physiological response to gravity and results in inadequate blood flow to the brain upon standing.

The medical definition of orthostatic intolerance includes symptoms that are exacerbated by upright posture and relieved by recumbent (lying down) position. The underlying mechanisms involve dysfunction in the autonomic nervous system, which controls involuntary bodily functions such as heart rate, blood pressure, and vasoconstriction.

Orthostatic intolerance can be a symptom of various medical conditions, including postural orthostatic tachycardia syndrome (POTS), neurogenic orthostatic hypotension, and other autonomic disorders. Proper diagnosis and management require a thorough evaluation by a healthcare professional to identify the underlying cause and develop an appropriate treatment plan.

... cardiovascular deconditioning; and decreased endurance and muscle mass. Radiation is perhaps the most insidious health hazard ...
"Cardiovascular Deconditioning in Weightlessness" (PDF). "NASA - Renal Stone Risk During Space Flight: Assessment and ... Without regular exercise and nourishment, there can be cardiovascular deterioration and loss in muscle strength. Dehydration ...
In the absence of gravity, blood pools in the upper torso and head, causing cardiovascular deconditioning. The Chibis suit ... Each crewman spent time in a Chibis suit for measurement of cardiovascular system responses to lower body negative pressure. ... They used the lower body negative pressure unit and a baroreflex neck cuff to test cardiovascular orthostatic function response ...
... but microgravity also leads to significant deconditioning of muscular and cardiovascular tissues. Once above the atmosphere, ...
Cardiolab (CDL) - To scan the cardiovascular system. (Built by CADMOS in Toulouse.) The EPM is operated according to ESA's ... Muscle de-conditioning/atrophy Endocrinology, Nutrition and Metabolism - Hormonal regulation; demineralization To correctly ... Research typically includes neuroscientific, cardiovascular, and physiological studies and investigations of metabolic ... and motion sensory coordination Cardiovascular and Respiratory Systems - Control of blood volume and distribution; fluid volume ...
... cardiovascular system adapts to microgravity conditions and is deconditioned on their return to Earth. Terason's was chosen as ...
Over time these deconditioning effects can impair astronauts' performance, increase their risk of injury, reduce their aerobic ... Cooke, J.P; Bancroft, R.W. (1966). "Some Cardiovascular Responses in Anesthetized Dogs During Repeated Decompressions to a Near ... Other significant effects include a slowing of cardiovascular system functions, decreased production of red blood cells (space ... capacity, and slow down their cardiovascular system. As the human body consists mostly of fluids, gravity tends to force them ...
Next to the skeletal and muscular system, the cardiovascular system is less strained in weightlessness than on Earth and is de- ... Parabolic flight studies have provided a broad range of results regarding changes in the cardiovascular system in a micro-g ... Many studies on the physiological effects of weightlessness on the cardiovascular system are done in parabolic flights. It is ... Abbasi, Jennifer (20 December 2016). "Do Apollo Astronaut Deaths Shine a Light on Deep Space Radiation and Cardiovascular ...
... to counter cardiovascular deconditioning in the microgravity environment. Exercise bikes are frequently used in cardiac ... The exercise bike has long been used for physical therapy because of the low-impact, safe, and effective cardiovascular ... The controlled and adjustable nature of stationary biking makes it an ideal choice for gradually improving cardiovascular ...
... cardiovascular deconditioning MeSH G09.330.553.400 - hemodynamic phenomena MeSH G09.330.553.400.095 - blood flow velocity MeSH ...
... space experiments The sojourn of astronauts in space elicits substantial deconditioning effects within the cardiovascular ... The incurring costs of akinesia and related disorders, such as osteoporosis, cardiovascular events, stroke and cancer are ...
The two dogs showed signs of "cardiovascular deconditioning" with dehydration, weight loss, loss of muscle and coordination and ...
... study of exercise as a possible countermeasure for the deconditioning which astronauts experience in their cardiovascular ...
ESA Study of the evolution of cardiovascular deconditioning phenomena under weightless conditions (CARDIOSCIENCE) - ESA Bone ... Study of the evolution of cardiovascular deconditioning phenomena under weightless conditions (CARDIOSCIENCE) Bone cell ... ESA Cardiovascular adaptation to weightlessness (RHYTHM) - ESA Effects of microgravity on the peripheral subcutaneous veno- ... CARDIOCOG-2 Cardiovascular adaptation to weightlessness (RHYTHM) Effects of microgravity on the peripheral subcutaneous veno- ...
... covers three areas - normal aging due to disuse and deconditioning, cardiovascular problems like ...
Cardiovascular Health Consequences of Long-Duration Space Flight (Vascular) Cardiovascular regulation during long-duration ... Levine, BD; Zuckerman, JH; Pawelczyk, JA (15 July 1997). "Cardiac atrophy after bed-rest deconditioning: a nonneural mechanism ... Most of these have been related to cardiovascular disease, but it is not clear whether this was due to pre-existing conditions ... Indeed, there are known and well-defined changes in the cardiovascular system with space flight: plasma volume is reduced; left ...
It seems that HMB is able to act on three of the four major mechanisms involved in muscle deconditioning (protein turnover, ... and decrease cardiovascular risks (Nissen et al., 2000). For all these reasons, HMB should be routinely used in muscle-wasting ...
It seems that HMB is able to act on three of the four major mechanisms involved in muscle deconditioning (protein turnover, ... and decrease cardiovascular risks (Nissen et al., 2000). For all these reasons, HMB should be routinely used in muscle-wasting ...
Cardiovascular complications including heart failure, chest pain, and arrhythmias. There are multiple causes of orthostatic ... Elderly deconditioned patients, especially after prolonged hospitalization, may have reduced muscle tone. Review of the ... Avoiding physical deconditioning in the elderly which helps maintain muscle tone in lower extremities External compression ... Physical deconditioning Sympathectomy The autonomic nervous system regulates various body processes and comprises the ...
The bicycle ergometer proved to be an excellent machine for aerobic exercise and cardiovascular conditioning, but it was not ... Thornton, WE; Rummel, JA (1977). "Muscular deconditioning and its prevention in spaceflight". In Johndton, RS; Dietlien, LF ( ... cardiac deconditioning, and bone loss; extravehicular activity (EVA); and vehicle landing and egress. EVA suits and launch and ... Exercise is not necessary on a short trip and crews did not feel that they suffered noticeable deconditioning, but they did ...
This deconditioning is often met with resistance to the accompanying lifestyle changes. The real risk attached to athlete's ... August 1996). "Cardiovascular preparticipation screening of competitive athletes. A statement for health professionals from the ... If the athlete is uncomfortable with having athlete's heart or if a differential diagnosis is difficult, deconditioning from ... Sachs KV, Harnke B, Mehler PS, Krantz MJ (March 2016). "Cardiovascular complications of anorexia nervosa: A systematic review ...
Joyner, Michael J.; Masuki, Shizue (December 2008). "POTS versus deconditioning: the same or different?". Clinical Autonomic ... the cardiovascular system, the nervous system, and circulation control system. Orthostatic intolerance is divided, roughly ... home-based test for the evaluation of neuro-cardiovascular autonomic dysfunction". ACNR, Advances in Clinical Neuroscience and ...
October 2005). "Vascular adaptation to deconditioning and the effect of an exercise countermeasure: results of the Berlin Bed ... "Head-down bed rest alters sympathetic and cardiovascular responses to mental stress". American Journal of Physiology. ... such as muscle atrophy and other forms of deconditioning such as arterial constriction. Besides lack of physical exercise it ...
fatigue - when it appears early in an exercise test, it is usually due to deconditioning (either through a sedentary lifestyle ... Dysfunctions involving the pulmonary, cardiovascular or neuromuscular systems have been frequently found to be associated with ... Kitzman, Delane W (2005). "Exercise Intolerance". Progress in Cardiovascular Diseases. 47 (6): 367-379. doi:10.1016/j.pcad. ...
The GLCS is a garment designed to help mitigate the effects of musculoskeletal deconditioning. It is partly inspired by the ... The CEVIS provides both aerobic and cardiovascular training using recumbent cycling activities. The workload placed on the ... muscle atrophy deconditioning (e.g. arterial constriction, bone density loss) symptoms similar to aging or disease head-ward ... and cardiovascular systems. Short arm centrifuges can be used to generate loading conditions greater than gravity that could ...
... averting the deconditioning that occurs during the immobilization of bed rest or space flight, due to a lack of gravireceptor ... Cardiovascular and Respiratory Improvement: Rebounding is said to directly yield impressive aerobic exercise benefits in terms ... a finding that might help identify acceleration parameters needed for the design of remedial procedures to avert deconditioning ...
Cardiovascular and Cerebrovascular Control on Return from ISS (CCISS) Cardiac Atrophy and Diastolic Dysfunction During and ... NASA Archived 2010-03-16 at the Wayback Machine Validation of Centrifugation as a Countermeasure for Otolith Deconditioning ... Cardiovascular) Test of Midodrine as a Countermeasure Against Post-flight Orthostatic Hypotension - Long (Midodrine-Long) Test ... NASA Cardiovascular and Cerebrovascular Control on Return from ISS (CCISS) (ISS Experiment) - NASA Cardiac Atrophy and ...
Extrinsic risk factors include deconditioning, hard surfaces, inadequate stretching and poor footwear. Study participants ... their injury risk by cutting down on mileage as it would be to motivate the sedentary population to decrease its cardiovascular ...
Cardiovascular disease: Cardiovascular disease has been related to lack of job control. Mental health: Exposure to occupational ... can be deconditioned. Mental health care today involves psychologists and social workers in increasing numbers. In 1977, ...
Physical therapy, rehabilitation, and counseling can help avoid deconditioning,: 733 and improve social participation, ... Cardiovascular Diagnosis and Therapy. 6 (1): 50-63. doi:10.3978/j.issn.2223-3652.2015.12.13. PMC 4731586. PMID 26885492. "About ...
... cardiovascular deconditioning; and decreased endurance and muscle mass. Radiation is perhaps the most insidious health hazard ...
Looga R. Reflex cardiovascular responses to lung inflation: a review. Respir Physiol. 1997. 109:95-106. [QxMD MEDLINE Link]. ... Deconditioning in patients with orthostatic intolerance. Neurology. 2012. 79:1435-1439. [QxMD MEDLINE Link]. ... Cardiovascular syncope has a poor prognosis unless specifically treated. Reflex syncope has an excellent prognosis. [45] . ... The Cardiovascular Health Study. CHS Collaborative Research Group. Hypertension. 1992. 19:508-519. [QxMD MEDLINE Link]. ...
... muscle weakness and cardiovascular deconditioning.. It could take about six months to get to Mars, and when the crew suddenly ...
Dysfunctional breathing and deconditioning are crucial factors for the evaluation of post-COVID-19 patients, as they can ... Some patients also exhibited dysfunctional states, such as deconditioning (15.8%) or pulmonary mechanical limitation (9.2%), ... 3) Results: Using CPET, cardiovascular diseases such as venous thromboembolism or ischemic and nonischemic heart disease were ... It is therefore reasonable to distinguish between cardiovascular disease and cardiovascular symptoms, in the absence of an ...
Further, he studies the malleability of this neural system to deconditioning and conditioning stimuli, as well as sex hormones ... of research that focused on mapping the cortical autonomic network associated with exercise and other reflex cardiovascular ...
The cuffs inflate and deflate in sync with a users heart beat, the company said, which it claims improves cardiovascular ... whether an elite athlete or deconditioned individual. After years of trials and tireless effort, we are thrilled to bring this ... PureFlow will considerably impact and improve the lives of anyone who is trying to increase their cardiovascular health, from ... "PureFlow is a revolutionary PassiveCardio technique to improve cardiovascular health for everyone, ...
Cardio-Deconditioning: This ESA-led experiment, involving international collaboration, focuses on understanding cardiovascular ...
... suggesting a cardiovascular limitation to exercise. These data do not support the hypothesis that the lower initial VO2max in ... Although the reduced exercise capacity appeared consistent with deconditioning, the patients had altered breathing mechanics ... the subjects with a reduced FEV1 was due to deconditioning. Although increased EELV at maximal exercise, reduced VO2max and a ... of reduced exercise capacity by an adequate exercise training program is generally accepted as evidence of deconditioning as ...
More attention should be paid to cardiovascular and musculoskeletal deconditioning as well as motivational factors to improve ... Structured exercise is considered an important cornerstone to achieve good glycemic control and improve cardiovascular risk ... glycemic control and cardiovascular risk profile in Type 2 diabetes patients. Based on the currently available literature, it ...
Cardiovascular Deconditioning MeSH DeCS ID:. 31972 Unique ID:. D018544 Documents indexed in the Virtual Health Library (VHL):. ... and use of anti-deconditioning devices. (From Nicogossian, Space Physiology and Medicine, 2d ed, pp294-297) ... and use of anti-deconditioning devices. (From Nicogossian, Space Physiology and Medicine, 2d ed, pp294-297). ...
Long-duration space missions in microgravity lead to deconditioning of the cardiovascular system as well as to atrophy of the ...
Activity prevents skeletal muscle deconditioning, which worsens functional status; however, activity does not appear to improve ... Formal exercise cardiac rehabilitation Cardiovascular Rehabilitation Cardiovascular rehabilitation may benefit some patients ... Complications include cardiovascular disorders... read more , hypertension Hypertension Hypertension is sustained elevation of ... Age-related changes in the heart and cardiovascular system lower the threshold for expression of heart failure. Interstitial ...
Cardiovascular and deconditioning. Assistance in Independet, Assisted or Memory Care Living Facility. ...
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... deconditioning of the cardiovascular, musculoskeletal, and neuromuscular systems. Deconditioning produces a multitude of ... Deconditioning presents operational problems during spaceflight and upon return to I-G. Muscular and cardiovascular ... One immediate and important objective of this research is to minimize the effects of deconditioning during spaceflight using ... Which reliable indicators of changes in fitness best describe the changes caused by deconditioning? ...
Part of the concerns occur during the course of a mission, while others - such as cardiovascular deconditioning, bone and ... an actual study estimates that more than 1.5 million annual deaths from cardiovascular causes worldwide were attributed to ... Global Sodium Consumption and Death from Cardiovascular Causes. New England Journal of Medicine. 2014, 371 (7): 624-634. ...
Central hypervolemia in the conscious rat: A model of cardiovascular deconditioning. J Appl Physiol (1985). 1996; 80(4): 1390- ... Supine cycling plus volume loading prevent cardiovascular deconditioning during bed rest. J Appl Physiol (1985). 2010; 108(5): ... Attenuated baroreflex control of sympathetic nerve activity after cardiovascular deconditioning in rats. Am J Physiol. 1998; ... 2 muscle atrophy3 and cardiovascular deconditioning.4 Accelerated bone loss in crew members in space is considered a critical ...
However, a transient moderate orthostatic hypotension suggested cardiovascular deconditioning after dive. CONCLUSIONS: This ... the medical management of this atypical project and the systematic clinical follow-up mostly targeted on the cardiovascular ...
Effects of Cardiovascular Conditioning and Deconditioning on the Expression and Phosphorylation Status of Connexin-4. Jillane ...
Maloni (1994) documented adverse physiologic outcomes related to complete bed rest, including cardiovascular deconditioning; ... CARDIOVASCULAR. ↑ Blood volume; plasma volume expansion greater than red cell mass expansion, leading to physiologic anemia of ... Assessments include review of the cardiovascular system, pulmonary system, renal system, hematologic system, and CNS. Fetal as ...
Wheelchair users may experience de-conditioning side effects, such as the loss of endurance or cardiovascular health. Walkers ...
Exercise can help strengthen unaffected muscles, prevent deconditioning, improve cardiovascular health, and help patients fight ...
... heart surgeries involves performing a safe exercise program to help improve cardiovascular health and address deconditioning. ... Pre and post-operative treatments include strengthening, balance and stability training, and improving cardiovascular fitness. ...
... cardiovascular deconditioning and blood loss. Not to mention, simulated gravity in space could ease the transition to low Earth ...
... deconditioning and QoL.,/p,}}, author = {{Cristea, Lucas and Olsson, Max and Currow, David and Johnson, Miriam and Sandberg, ... body mass index and the presence of respiratory and cardiovascular disease.,/p,,p,RESULTS: Worse breathlessness was related to ... body mass index and the presence of respiratory and cardiovascular disease. ... body mass index and the presence of respiratory and cardiovascular disease. ...
Cardiovascular deconditioning leading to persistent tachycardia has been described after SARS and may also play a role in post- ... Cardiovascular deconditioning is a potential consequence of COVID- 19, as periods of prolonged bedrest can lead to resting ... Cardiovascular deconditioning is a potential consequence of COVID-19, as periods of prolonged bedrest can lead to resting ... Deconditioning alone however does not explain the many other symptoms present in POTS and also seen in post-COVID syndrome, ...
... which may contribute to cardiovascular deconditioning during extended spaceflight. Mice were exposed to spaceflight for 15 days ... Cardiac deconditioning and atrophy on Earth are associated with altered Trp53 and oxidative stress-related pathways, but the ... Cardiac deconditioning and atrophy on Earth are associated with altered Trp53 and oxidative stress-related pathways, but the ... Magnesium (Mg) is a pivotal and very complex component of healthy aging in the cardiovascular-muscle-bone triad. Low Mg levels ...
UCSF News reports on a recent study led by UCSF researchers linking post-traumatic stress to a higher risk for cardiovascular ... The group hypothesized that this may be associated with a vascular deconditioning state. These findings have the potential for ... two measures that relate to cardiovascular risk. The results showed that a short term exposure to physical inactivity leads to ... in particular the cardiovascular system, fares under the rigors of [...] ...
... cardiovascular and sensory-motor deconditioning, immune, hormonal and metabolic changes . Moreover, recently a new suite of ... A set of measurements will assess the changes in the cardiovascular, neuro-ophthalmological, hematological, metabolic, ... Any history or presence of clinically relevant cardiovascular, neurological or ENT (especially orthostatic hypotension and ... Overall, spaceflight induces physiological multi-system deconditioning which may impact astronauts efficiency and create ...
... and cardiovascular deconditioning. Increased activity also decreases the patients risk for developing skin breakdown or ... However, inpatient rehabilitation may be appropriate for patients with Paget disease who have become deconditioned and are ...
  • Astronauts returning to Earth after living aboard the International Space Station for that amount of time have exhibited balance control problems, muscle weakness and cardiovascular deconditioning. (sciencedaily.com)
  • 5 Astronauts also experience deconditioning of the cardiovascular system that increases with the duration of microgravity exposure. (openventio.org)
  • Overall, spaceflight induces physiological multi-system deconditioning which may impact astronauts' efficiency and create difficulties upon their return to normal gravity. (veeva.com)
  • Long-duration space missions in microgravity lead to deconditioning of the cardiovascular system as well as to atrophy of the bones and muscles. (amst.co.at)
  • The purpose of our biomechanical analysis in space is to provide a program of exercise countermeasures that will minimize the operational consequences of microgravity-induced deconditioning by providing individualized exercise 'prescriptions' for each crew member. (arielnet.com)
  • Task requirements have been defined in terms of the musculoskeletal and neuromuscular system demands induced by microgravity, and training protocols developed to address deconditioning in these systems to serve as the basis for training prescriptions. (arielnet.com)
  • Exposure to the weightlessness experienced in microgravity environments leads to bone loss, 2 muscle atrophy 3 and cardiovascular deconditioning. (openventio.org)
  • They produce changes in body composition (including body fluid redistribution), cardiovascular and skeletal muscle characteristics that resemble the effects of microgravity. (veeva.com)
  • More attention should be paid to cardiovascular and musculoskeletal deconditioning as well as motivational factors to improve long-term treatment adherence and clinical efficacy. (eur.nl)
  • In fact, exercise is the only countermeasure that can potentially counteract the combined cardiovascular, musculoskeletal and neuromuscular effects of adaptation. (arielnet.com)
  • One of the ways the human body reacts to the reduced physiological and mechanical demands of micro-gravity is by a deconditioning of the cardiovascular, musculoskeletal, and neuromuscular systems. (arielnet.com)
  • Martin explains the main, underappreciated advantage of HIIT, which revolves around the "intensity-duration trade-off": the higher intensity you make exercise, the shorter your workouts can be while still triggering improvements in metabolism, cardiovascular health, and mitochondrial capacity. (artofmanliness.com)
  • The higher intensity you make exercise, the shorter your workouts can be, while still triggering improvements in metabolism, cardiovascular health, mitochondrial capacity. (artofmanliness.com)
  • iCPET is required to tease out deconditioning vs mitochondrial dysfunction vs preload dependence. (medscape.com)
  • Spinal orthoses can decrease pain associated with weight bearing, thus improving the patient's ability to participate in ambulatory activities and reducing effects related to immobility, such as muscle atrophy, bone loss, and cardiovascular deconditioning. (medscape.com)
  • Results from experiments on the Gemini, Apollo, and Skylab missions suggest that regular exercise is helpful in minimizing several aspects of spaceflight deconditioning (1,2,3). (arielnet.com)
  • Deconditioning produces a multitude of physical changes such as loss of muscle mass, decreases in bone density and body calcium. (arielnet.com)
  • Cardiovascular rehabilitation after heart surgeries involves performing a safe exercise program to help improve cardiovascular health and address deconditioning. (k-pt.com)
  • However, inpatient rehabilitation may be appropriate for patients with Paget disease who have become deconditioned and are unable to be independent or care for themselves at home. (medscape.com)
  • Physical therapy (PT) can play an important role in the treatment process and rehabilitation of patients with Paget disease by helping to maintain or improve muscle strength, maintain joint range of motion (ROM) and flexibility, increase endurance, and avoid deconditioning. (medscape.com)
  • PureFlow is a revolutionary PassiveCardio technique to improve cardiovascular health for everyone, whether an elite athlete or deconditioned individual. (massdevice.com)
  • PureFlow will considerably impact and improve the lives of anyone who is trying to increase their cardiovascular health, from an elite athlete to a deconditioned individual," CEO Andrew Barile said in a press release. (massdevice.com)
  • Wheelchair users may experience de-conditioning side effects, such as the loss of endurance or cardiovascular health. (balancecrutch.com)
  • Exercise can help strengthen unaffected muscles, prevent deconditioning, improve cardiovascular health, and help patients fight fatigue and depression. (projectwalkhouston.com)
  • For starters, the negative health effects zero gravity can have on spacefarers are myriad, including muscle shrinkage, cardiovascular deconditioning and blood loss. (dot.la)
  • Promote wellness among your team and those you serve- enhance mobility, strength, and cardiovascular health with our seated walking devices. (onthemuv.com)
  • Backed by research and testimonials, our products have demonstrated tangible benefits in enhancing mobility, strength, and cardiovascular health. (onthemuv.com)
  • Describe cardiovascular symptoms and complications associated with post-COVID conditions. (cdc.gov)
  • Today I'll present an overview of post-COVID conditions as an introduction of the main presentation on evaluating and supporting patients with cardiovascular symptoms and complications following COVID-19. (cdc.gov)
  • Chronic kidney disease is directly related to cardiovascular disorders. (bvsalud.org)
  • Part of the concerns occur during the course of a mission, while others - such as cardiovascular deconditioning, bone and muscle losses and orthostatic intolerance - manifest themselves mainly upon return to earth only. (biomedcentral.com)
  • Scores were compared as z-scores across scales and analysed using multivariable linear regression, adjusted for smoking, body mass index and the presence of respiratory and cardiovascular disease. (lu.se)
  • Which reliable indicators of changes in fitness best describe the changes caused by deconditioning? (arielnet.com)
  • The New York-based company said that the system was designed on a concept called external counter-pulsation, and was originally designed to improve unhealthy cardiovascular function. (massdevice.com)
  • Structured exercise is considered an important cornerstone to achieve good glycemic control and improve cardiovascular risk profile in Type 2 diabetes. (eur.nl)
  • This paper reviews the wide pathophysiological problems associated with Type 2 diabetes and discusses the benefits of exercise therapy on phenotype characteristics, glycemic control and cardiovascular risk profile in Type 2 diabetes patients. (eur.nl)
  • Specific measures include creation of artificial gravity, exercise, low-level lower body negative pressure, and use of anti-deconditioning devices. (bvsalud.org)
  • What type of exercise devices such as weight training, bicycling, rowing, swimming, running, etc. are necessary to train all of the organ systems affected by deconditioning? (arielnet.com)
  • The cuffs inflate and deflate in sync with a user's heart beat, the company said, which it claims improves cardiovascular function. (massdevice.com)
  • D-12 and MDP contribute complimentary information, where affective and emotional responses may be related to function, deconditioning and QoL. (lu.se)
  • A clinical study led by UCSF Vascular Surgeon Marlene Grenon, M.D., C.M. looked at the effects of physical inactivity on vascular endothelial function and arterial stiffness, two measures that relate to cardiovascular risk. (ucsf.edu)
  • We had patients who were excessively deconditioned, in the hospital for over 4 months and after using miniTREAD were discharged in under 3 weeks. (onthemuv.com)
  • Determine which clinical assessments and tests are needed for a patient with cardiovascular symptoms. (cdc.gov)
  • UCSF News reports on a recent study led by UCSF researchers linking post-traumatic stress to a higher risk for cardiovascular disease and death. (ucsf.edu)
  • Understanding the underlying mechanisms of these processes and developing efficient countermeasures to prevent, limit or reverse this deconditioning remain important challenges and major priorities for manned space programs. (veeva.com)
  • Pre and post-operative treatments include strengthening, balance and stability training, and improving cardiovascular fitness. (k-pt.com)
  • The leading cause of death in both years was cardiovascular diseases, while cancer was the third leading cause in 1978 and the second in 2007. (who.int)
  • CPET confirms the presence of deconditioning/myopathy, which is ubiquitous both in isolation or combined with another disorder, and quantifies its severity. (medscape.com)
  • As a majority of COPD patients are elderly and have multiple co-morbidities including cardiovascular disease and diabetes, they are notably susceptible to severe complications of COVID-19. (nih.gov)
  • Compared with obese children, severely obese children have increased risk for negative health outcomes in adulthood, including cardiovascular disease, insulin resistance, sleep apnea, and severe obesity (6-12). (cdc.gov)
  • So aging patients with IBD are at even greater risk for many of the classic inflammation-linked health outcomes, including cardiovascular disease, cancer, obesity , skin issues, arthritis , and skeletal muscle loss. (time.com)
  • No permanent cardiovascular adaptations following 60 days of HDT bed rest were observed. (dlr.de)
  • Exercise-induced cardiovascular adaptations and approach to exercise and cardiovascular disease. (msdmanuals.com)
  • Modulation of cardiac/cardiovascular responses and adaptations including influence of sex, aging, pregnancy, and acute/chronic exercise on metabolic function and cardiac, vascular smooth muscle, and vascular endothelial function(s). (nih.gov)
  • Physical activity may help prevent cardiovascular disease, improve glucose control in those with diabetes, and maintain muscle mass. (nih.gov)
  • The purpose is not only to prevent musculoskeletal deconditioning but also to prevent cardiovascular deconditioning. (nih.gov)
  • A sedentary lifestyle occurring soon after spinal cord injury (SCI) may be in contrast to a preinjury history of active physical engagement and is thereafter associated with profound physical deconditioning sustained throughout the lifespan. (bath.ac.uk)
  • Maher, JL , McMillan, DW & Nash, MS 2017, ' Exercise and Health-Related Risks of Physical Deconditioning After Spinal Cord Injury ', Topics in spinal cord injury rehabilitation , vol. 23, no. 3, pp. 175-187. (bath.ac.uk)
  • Nash, Mark S. / Exercise and Health-Related Risks of Physical Deconditioning After Spinal Cord Injury . (bath.ac.uk)
  • Concerns in spinal cord injury (SCI) include its ability to compromise cardiovascular control, with associated short- and long-term consequences. (medscape.com)
  • Microgravity has deleterious effects on the cardiovascular system. (dlr.de)
  • In astronauts, sensory and motor relationships are altered soon after liftoff, without apparent anatomical or physiological compromise although "deconditioning" accompanies prolonged exposure to microgravity. (nih.gov)
  • The cardiovascular and respiratory systems are also adversely affected by inactivity. (mg-mi.org)
  • NEUROCOG (study how humans perceive space, what role the sensory information of sight, balance, motion and position plays in this, and how human perception is affected by weightlessness), CARDIOCOG (study of changes in the cardiovascular and respiratory systems of humans in zero-G), and BMI (monitoring changes in blood pressure rhythms over 24 hours). (spaceref.com)
  • During his talk at NIH, Krimigis said astronauts traveling in space for long periods of time likely have a higher risk for a wide range of medical problems, including balance disorders, visual alterations, cardiovascular deconditioning, bone loss, and cancer. (nih.gov)
  • Listed were 52 kinds of physical changes routinely experienced in space by orbiting astronauts, including osteoporosis, cardiovascular difficulties and alterations in the distribution of body fluids. (discovermagazine.com)
  • In other patients who have been hospitalized and very ill, or inactive due to severe fatigue, the heart may race due to "deconditioning" (being out of shape). (uabmedicine.org)
  • MG treatments will usually reduce the amount of exercise-induced fatigue caused by MG, but the person is left with fatigue because that individual is deconditioned. (mg-mi.org)
  • Stroke is a leading reason for incapacity that outcomes not only in persistent neurological deficits, but also profound bodily deconditioning that propagates disability and worsens cardiovascular danger. (neurolumabrainpill.com)
  • Deconditioning affects the muscles and cardiopulmonary system. (mg-mi.org)
  • Clinical studies investigating the responses of the cardiovascular system to trauma or surgery including arrhythmias associated with cardiac surgery or cardiopulmonary bypass, cardiac sudden death, resuscitation, stenting, pacemakers, cardiovascular injury and repair, and myocardial ischemia/reperfusion injury. (nih.gov)
  • Neural control of the cardiovascular system including central and peripheral autonomic physiology, pharmacology, and receptor mechanisms in healthy and diseased populations. (nih.gov)
  • It is well known that people put up-stroke have decrease heart charges and oxygen consumption at peak effort throughout a graded train test when in comparison with healthy sedentary age-matched peers 12 , 14 This may be a result of impaired autonomic management of the cardiovascular system in addition to pharmacologic remedy (beta blockers). (neurolumabrainpill.com)
  • The American College of Cardiology (ACC) has issued an expert consensus clinical guidance document for the evaluation and management of adults with key cardiovascular consequences of COVID-19. (medscape.com)
  • Association of all-cause and cardiovascular mortality with high levels of physical activity and concurrent coronary artery calcification. (msdmanuals.com)
  • CCHS and Integrative Vascular Physiology and Pathology (IVPP) have shared interests in topics related to blood pressure regulation, hypertension, neural control of the cardiovascular system, and micro- or regional circulation. (nih.gov)
  • He has found that "during a six-month space mission, an astronaut's cardiovascular system can age by up to 10 or 20 years. (discovermagazine.com)
  • This has increased patients' vulnerability to physical deconditioning, depression, and social isolation. (nih.gov)
  • Examples range from physical deconditioning, which is common after illness, especially hospitalization. (nih.gov)
  • Causes of rapid heart rate can include being out of shape (deconditioning) due to prolonged illness and too much bed rest. (uabmedicine.org)
  • A change in cardiovascular function resulting in a reduction in BLOOD VOLUME , and reflex DIURESIS . (bvsalud.org)
  • Reduction in left ventricular wall thickness after deconditioning in highly trained Olympic athletes. (bmj.com)
  • Among attainable interventions, cardio coaching is well-known to reinforce cardiovascular and motor capabilities but might also induce beneficial effects on cognitive features. (neurolumabrainpill.com)
  • Others might include changes in breathing, heart rate, or other forms of cardiovascular function, based on each person's response to the virus. (nih.gov)
  • These marked differences have led to increased interest in detection of the central blood pressure profile as an important clinical marker for increased cardiovascular risk. (healthybpclub.com)
  • That is not to say load doesn't have other effects such as hormonal and cardiovascular as well. (thesciencept.com)
  • Treatment strategies to slow progression and reduce cardiovascular risk are similar. (nih.gov)
  • On the other hand, they may support that fear of pain and injury may be more disabling than pain itself, and that deconditioning is a result of altered behaviour reflecting attitudes towards low back pain in society, and information and advice given in primary healthcare. (medicaljournals.se)
  • When used in a cardiovascular circuit, the moonwalker maintains a child's heart rate to reach optimal levels for healthy & age appropriate conditioning. (abllab.com)
  • Experts discuss the current role of imaging modalities, particularly TTE and CMR, in monitoring and diagnosing cardiovascular diseases that can lead to heart failure. (medscape.com)
  • Calf measurements (left leg only) are taken with the ISOG device, a custom-sewn fabric cuff that fits over the calf, using the knee and lower foot as fixed reference points, to provide a rough index of deconditioning in zero-G and effectiveness of countermeasures. (spaceref.com)