Congenital, inherited, or acquired anomalies of the CARDIOVASCULAR SYSTEM, including the HEART and BLOOD VESSELS.
A syndrome of defective gonadal development in phenotypic females associated with the karyotype 45,X (or 45,XO). Patients generally are of short stature with undifferentiated GONADS (streak gonads), SEXUAL INFANTILISM, HYPOGONADISM, webbing of the neck, cubitus valgus, elevated GONADOTROPINS, decreased ESTRADIOL level in blood, and CONGENITAL HEART DEFECTS. NOONAN SYNDROME (also called Pseudo-Turner Syndrome and Male Turner Syndrome) resembles this disorder; however, it occurs in males and females with a normal karyotype and is inherited as an autosomal dominant.
A disorder caused by hemizygous microdeletion of about 28 genes on chromosome 7q11.23, including the ELASTIN gene. Clinical manifestations include SUPRAVALVULAR AORTIC STENOSIS; MENTAL RETARDATION; elfin facies; impaired visuospatial constructive abilities; and transient HYPERCALCEMIA in infancy. The condition affects both sexes, with onset at birth or in early infancy.
Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.
Activities or games, usually involving physical effort or skill. Reasons for engagement in sports include pleasure, competition, and/or financial reward.
Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.
Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
Enlargement of the LEFT VENTRICLE of the heart. This increase in ventricular mass is attributed to sustained abnormal pressure or volume loads and is a contributor to cardiovascular morbidity and mortality.
PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
A class of lipoproteins of small size (18-25 nm) and light (1.019-1.063 g/ml) particles with a core composed mainly of CHOLESTEROL ESTERS and smaller amounts of TRIGLYCERIDES. The surface monolayer consists mostly of PHOSPHOLIPIDS, a single copy of APOLIPOPROTEIN B-100, and free cholesterol molecules. The main LDL function is to transport cholesterol and cholesterol esters to extrahepatic tissues.
A generic term for fats and lipoids, the alcohol-ether-soluble constituents of protoplasm, which are insoluble in water. They comprise the fats, fatty oils, essential oils, waxes, phospholipids, glycolipids, sulfolipids, aminolipids, chromolipids (lipochromes), and fatty acids. (Grant & Hackh's Chemical Dictionary, 5th ed)
Abnormalities in the serum levels of LIPIDS, including overproduction or deficiency. Abnormal serum lipid profiles may include high total CHOLESTEROL, high TRIGLYCERIDES, low HIGH DENSITY LIPOPROTEIN CHOLESTEROL, and elevated LOW DENSITY LIPOPROTEIN CHOLESTEROL.
A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
Cholesterol which is contained in or bound to low density lipoproteins (LDL), including CHOLESTEROL ESTERS and free cholesterol.
A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
Disturbances in the body's WATER-ELECTROLYTE BALANCE.
A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.
Deficiency of sodium in the blood; salt depletion. (Dorland, 27th ed)
Agents that affect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume.
A publication issued at stated, more or less regular, intervals.
Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed)
A group of mental disorders associated with organic brain damage and caused by poisoning from alcohol.
A condition of having excess fat in the abdomen. Abdominal obesity is typically defined as waist circumferences of 40 inches or more in men and 35 inches or more in women. Abdominal obesity raises the risk of developing disorders, such as diabetes, hypertension and METABOLIC SYNDROME X.
A status with BODY WEIGHT that is grossly above the acceptable or desirable weight, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
A cluster of metabolic risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome X include excess ABDOMINAL FAT; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state. (from AHA/NHLBI/ADA Conference Proceedings, Circulation 2004; 109:551-556)
Fatty tissue in the region of the ABDOMEN. It includes the ABDOMINAL SUBCUTANEOUS FAT and the INTRA-ABDOMINAL FAT.
An indicator of body density as determined by the relationship of BODY WEIGHT to BODY HEIGHT. BMI=weight (kg)/height squared (m2). BMI correlates with body fat (ADIPOSE TISSUE). Their relationship varies with age and gender. For adults, BMI falls into these categories: below 18.5 (underweight); 18.5-24.9 (normal); 25.0-29.9 (overweight); 30.0 and above (obese). (National Center for Health Statistics, Centers for Disease Control and Prevention)
Individuals who have developed skills, physical stamina and strength or participants in SPORTS or other physical activities.
The condition of being heterozygous for hemoglobin S.
The field of medicine concerned with physical fitness and the diagnosis and treatment of injuries sustained in exercise and sports activities.
Injuries incurred during participation in competitive or non-competitive sports.
Persons including soldiers involved with the armed forces.
Lack of perfusion in the EXTREMITIES resulting from atherosclerosis. It is characterized by INTERMITTENT CLAUDICATION, and an ANKLE BRACHIAL INDEX of 0.9 or less.
NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
The process of discovering or asserting an objective or intrinsic relation between two objects or concepts; a faculty or power that enables a person to make judgments; the process of bringing to light and asserting the implicit meaning of a concept; a critical evaluation of a person or situation.
Pathological processes involving any one of the BLOOD VESSELS in the vasculature outside the HEART.
A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
A form of heart block in which the electrical stimulation of HEART VENTRICLES is interrupted at either one of the branches of BUNDLE OF HIS thus preventing the simultaneous depolarization of the two ventricles.
The front third of the eyeball that includes the structures between the front surface of the cornea and the front of the VITREOUS BODY.
An impulse-conducting system composed of modified cardiac muscle, having the power of spontaneous rhythmicity and conduction more highly developed than the rest of the heart.
Regulation of the rate of contraction of the heart muscles by an artificial pacemaker.
Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
Drugs that are used to treat RHEUMATOID ARTHRITIS.
A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
A subspecialty of internal medicine concerned with the study of inflammatory or degenerative processes and metabolic derangement of connective tissue structures which pertain to a variety of musculoskeletal disorders, such as arthritis.
Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.
Organic compounds that contain GOLD as an integral part of the molecule. Some are used as ANTIRHEUMATIC AGENTS. The term chrysotherapy derives from an ancient Greek term for gold.

The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development. (1/190)

Csx/Nkx2.5 is a vertebrate homeobox gene with a sequence homology to the Drosophila tinman, which is required for the dorsal mesoderm specification. Recently, heterozygous mutations of this gene were found to cause human congenital heart disease (Schott, J.-J., Benson, D. W., Basson, C. T., Pease, W., Silberbach, G. M., Moak, J. P., Maron, B. J., Seidman, C. E. and Seidman, J. G. (1998) Science 281, 108-111). To investigate the functions of Csx/Nkx2.5 in cardiac and extracardiac development in the vertebrate, we have generated and analyzed mutant mice completely null for Csx/Nkx2.5. Homozygous null embryos showed arrest of cardiac development after looping and poor development of blood vessels. Moreover, there were severe defects in vascular formation and hematopoiesis in the mutant yolk sac. Interestingly, TUNEL staining and PCNA staining showed neither enhanced apoptosis nor reduced cell proliferation in the mutant myocardium. In situ hybridization studies demonstrated that, among 20 candidate genes examined, expression of ANF, BNP, MLC2V, N-myc, MEF2C, HAND1 and Msx2 was disturbed in the mutant heart. Moreover, in the heart of adult chimeric mice generated from Csx/Nkx2.5 null ES cells, there were almost no ES cell-derived cardiac myocytes, while there were substantial contributions of Csx /Nkx2.5-deficient cells in other organs. Whole-mount &bgr;-gal staining of chimeric embryos showed that more than 20% contribution of Csx/Nkx2. 5-deficient cells in the heart arrested cardiac development. These results indicate that (1) the complete null mutation of Csx/Nkx2.5 did not abolish initial heart looping, (2) there was no enhanced apoptosis or defective cell cycle entry in Csx/Nkx2.5 null cardiac myocytes, (3) Csx/Nkx2.5 regulates expression of several essential transcription factors in the developing heart, (4) Csx/Nkx2.5 is required for later differentiation of cardiac myocytes, (5) Csx/Nkx2. 5 null cells exert dominant interfering effects on cardiac development, and (6) there were severe defects in yolk sac angiogenesis and hematopoiesis in the Csx/Nkx2.5 null embryos.  (+info)

Regression of cardiac abnormalities after replacement therapy in Addison's disease. (2/190)

OBJECTIVE: To evaluate by echocardiography the cardiac structure and function in patients with primary adrenocortical insufficiency. DESIGN AND METHODS: Two-dimensionally guided M-mode echocardiograms and spectral Doppler studies were performed in seven consecutive patients with newly diagnosed autoimmune primary adrenal failure before and 4-8 months after an adequate regimen of steroid substitution. Echocardiographic parameters were also studied in ten healthy controls. RESULTS: In the cases with untreated Addison's disease, both left ventricular end-systolic and end-diastolic dimensions were significantly reduced in comparison with those in controls (P<0.01). Four patients had echocardiographic signs of mitral valve prolapse (MVP) at the anterior leaflet, with no evidence of mitral regurgitation by Doppler echocardiography. Systolic clicks characteristic of MVP were present on auscultation in two of these cases. Left ventricular chamber size normalized, i.e. significantly increased (P<0.01), and both echocardiographic and physical signs of MVP resolved after steroid substitution in all patients. All other echocardiographic indices were normal before and after treatment. CONCLUSIONS: Patients with untreated Addison's disease have cardiac abnormalities which regress after steroid substitution. A valvular-ventricular disproportion due to the hypovolemic state could explain these findings.  (+info)

Extraembryonic venous obstructions lead to cardiovascular malformations and can be embryolethal. (3/190)

OBJECTIVE: To expand our knowledge concerning the effect of placental blood flow on human heart development, we used an embryonic chicken model in which extraembryonic blood flow was manipulated. METHODS: First, one of the three major vitelline veins was ligated, while blood flow was visualized with Indian ink. In this way, we could study the effect of different ligation positions on intracardiac flow patterns. Secondly, these vitelline veins were ligated permanently with a microclip until cardiac septation was completed, thereafter, the hearts were morphologically evaluated. In this way, we could study the impact of the ligation position on the severity and frequency of heart malformations. On combining the results, we were able to study the effect of different intracardiac flow patterns on heart development. RESULTS: Although ligation of each vein resulted in different intracardiac flow patterns, long-term ligation resulted in similar cardiovascular malformations in survivors. These consisted mainly of ventricular septum defects (VSDs), semilunar valve anomalies, and pharyngeal arch artery malformations. There was no significant difference (p > 0.05) between the ligation position and the incidence of cardiovascular malformations. However, the percentage mortality after clipping the left lateral vitelline vein was significantly higher (p < 0.05) than after ligation of either the right lateral or posterior vitelline vein. CONCLUSIONS: Early extraembryonic venous obstruction leads to altered flow patterns, which probably result in shear stress changes. In postseptation stages, these result in a spectrum of cardiovascular malformations irrespective of the ligation position. A diminished incidence of VSDs in the oldest stage was attributed to delayed closure of the interventricular foramen.  (+info)

alyron, an insertional mutation affecting early neural crest development in zebrafish. (4/190)

alyronz12 (aln) is a recessive lethal mutation that affects early stages of neural crest development in the zebrafish. alyron appears to be an insertional mutation as the mutation was generated following microinjection of plasmid DNA into one-cell embryos and the stably integrated transgenic sequences are closely linked to the mutation. The insertion site harbors multiple copies of the plasmid sequence that have experienced complex rearrangements. Host-insert junction fragments have been molecularly cloned and host sequences adjacent to the transgene have been used to map the mutation to the distal arm of linkage group 15. alyron function is required cell-autonomously in the neural crest lineage. alyron mutants have a severe but not complete deficit of premigratory neural crest as judged by reduced expression of several markers associated with early stages of neural crest development. Lack of premigratory neural crest is likely to account for the two most conspicuous characteristics of alyron mutants: the absence of body pigmentation and the inability to affect blood circulation. The neural crest phenotype of alyron mutants resembles that observed in mouse mutants that lack Pax-3 or both Wnt-1 and Wnt-3a function, and expression of the zebrafish homologues of these genes is greatly reduced in the dorsal neural keels of alyron mutants. In contrast, ventral neural keel identity appears unaffected. Given our findings that the mutation is unlinked to pax or wnt genes that have been described in the zebrafish, we propose that alyron is a novel gene function required for the specification and/or proliferative expansion of neural crest progenitors.  (+info)

Double aortic arch in a Siamese cat. (5/190)

A double aortic arch is described in an 8-week-old female Siamese cat. In this case a vascular ring anomaly consistent with a double aortic arch is described in a cat. Stridor and dysphagia were noted in the cat. Radiography showed an esophageal dilation, with constriction at the fifth intercostal space. At necropsy, the esophagus and trachea were constricted at the base of the heart. The cause of the constriction of both the esophagus and trachea was a vascular ring formed by well-developed right and left aortic arches. The ascending aorta divided into two asymmetrical arches. The right aortic arch was larger than the left. The origin of the major arteries from the aortic arches were anomalous.  (+info)

Ontogenetic aspects of hypertension development: analysis in the rat. (6/190)

In this review, we attempt to outline the age-dependent interactions of principal systems controlling the structure and function of the cardiovascular system in immature rats developing hypertension. We focus our attention on the cardiovascular effects of various pharmacological, nutritional, and behavioral interventions applied at different stages of ontogeny. Several distinct critical periods (developmental windows), in which particular stimuli affect the further development of the cardiovascular phenotype, are specified in the rat. It is evident that short-term transient treatment of genetically hypertensive rats with certain antihypertensive drugs in prepuberty and puberty (at the age of 4-10 wk) has long-term beneficial effects on further development of their cardiovascular apparatus. This juvenile critical period coincides with the period of high susceptibility to the hypertensive effects of increased salt intake. If the hypertensive process develops after this critical period (due to early antihypertensive treatment or late administration of certain hypertensive stimuli, e.g., high salt intake), blood pressure elevation, cardiovascular hypertrophy, connective tissue accumulation, and end-organ damage are considerably attenuated compared with rats developing hypertension during the juvenile critical period. As far as the role of various electrolytes in blood pressure modulation is concerned, prohypertensive effects of dietary Na+ and antihypertensive effects of dietary Ca2+ are enhanced in immature animals, whereas vascular protective and antihypertensive effects of dietary K+ are almost independent of age. At a given level of dietary electrolyte intake, the balance between dietary carbohydrate and fat intake can modify blood pressure even in rats with established hypertension, but dietary protein intake affects the blood pressure development in immature animals only. Dietary protein restriction during gestation, as well as altered mother-offspring interactions in the suckling period, might have important long-term hypertensive consequences. The critical periods (developmental windows) should be respected in the future pharmacological or gene therapy of human hypertension.  (+info)

Effects of bone marrow transplantation on the cardiovascular abnormalities in canine mucopolysaccharidosis VII. (7/190)

The genetic mucopolysaccharidoses (MPS) are a family of lysosomal storage diseases resulting from defective catabolism of glycosaminoglycans (GAGs). Echocardiographic abnormalities in dogs with MPS type VII (Sly syndrome, beta-glucuronidase deficiency) included mitral valve thickening and insufficiency, large aortic dimensions in both the long and short axes, and thickened aortic valves. Grossly, at post mortem examination, there was nodular thickening of the mitral valve, a prominent ductus diverticulum, and a dilated aorta with thickened walls. Histologically, cytoplasmic vacuolation was seen in cells of the mitral valves, coronary arteries, and aorta. By electron microscopy, the cells of the mitral valve were packed with electron-lucent cytoplasmic vacuoles. The mean residual activity of beta-glucuronidase in the aorta and myocardium was <1% of normal, the mean hexosaminidase A activity >2. 5 times normal, and the mean GAG concentrations more than twice normal. In three MPS VII dogs that received heterologous BMT at 6 weeks of age, the echocardiographic abnormalities were improved, and the histopathologic and ultrastructural pathology was reduced. In the aorta and myocardium, the mean beta-glucuronidase activity of the BMT group was 4.5% and 11% of normal, respectively, and the hexosaminidase A activity and GAG concentrations were normalized. Bone Marrow Transplantation (2000) 25, 1289-1297.  (+info)

New insights into the assembly of extracellular microfibrils from the analysis of the fibrillin 1 mutation in the tight skin mouse. (8/190)

The Tight skin (Tsk) mutation is a duplication of the mouse fibrillin 1 (Fbn1) gene that results in a larger (418 kD) than normal (350 kD) protein; Tsk/+ mice display increased connective tissue, bone overgrowth, and lung emphysema. Lung emphysema, bone overgrowth, and vascular complications are the distinctive traits of mice with reduced Fbn1 gene expression and of Marfan syndrome (MFS) patients with heterozygous fibrillin 1 mutations. Although Tsk/+ mice produce equal amounts of the 418- and 350-kD proteins, they exhibit a relatively mild phenotype without the vascular complications that are associated with MFS patients and fibrillin 1-deficient mice. We have used genetic crosses, cell culture assays and Tsk-specific antibodies to reconcile this discrepancy and gain new insights into microfibril assembly. Mice compound heterozygous for the Tsk mutation and hypomorphic Fbn1 alleles displayed both Tsk and MFS traits. Analyses of immunoreactive fibrillin 1 microfibrils using Tsk- and species-specific antibodies revealed that the mutant cell cultures elaborate a less abundant and morphologically different meshwork than control cells. Cocultures of Tsk/Tsk fibroblasts and human WISH cells that do not assemble fibrillin 1 microfibrils, demonstrated that Tsk fibrillin 1 copolymerizes with wild-type fibrillin 1. Additionally, copolymerization of Tsk fibrillin 1 with wild-type fibrillin 1 rescues the abnormal morphology of the Tsk/Tsk aggregates. Therefore, the studies suggest that bone and lung abnormalities of Tsk/+ mice are due to copolymerization of mutant and wild-type molecules into functionally deficient microfibrils. However, vascular complications are not present in these animals because the level of functional microfibrils does not drop below the critical threshold. Indirect in vitro evidence suggests that a potential mechanism for the dominant negative effects of incorporating Tsk fibrillin 1 into microfibrils is increased proteolytic susceptibility conferred by the duplicated Tsk region.  (+info)

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This study showed that preterm infants have more than twice as many cardiovascular malformations as do infants born at term and that 1 of 6 infants with cardiovascular malformations is born preterm. It also showed, not surprisingly, that there is an increased mortality rate for infants born both preterm and with a cardiovascular malformation. The additional effect of cardiovascular malformations on mortality rates is most marked for term and near-term infants, for whom mortality rates are otherwise low. All mortality rates quoted in this study are from all causes in the first 1 year of life, not necessarily as a result of the cardiovascular malformation. We were not able to determine retrospectively the contribution of the cardiovascular malformations to the deaths. In a previous study of infants with esophageal atresia, we showed a sevenfold increase in mortality rates for those who also had a cardiovascular malformation but the heart defect was mainly a marker of multiple abnormalities and ...
After birth, gas exchange is achieved in the lung, whereas prenatally it occurs in the placenta. This is associated with differences in blood flow patterns in the fetus as compared with the postnatal circulation. Congenital cardiovascular malformations are associated with haemodynamic changes in the fetus, which differ from those occurring postnatally. Obstruction to cardiac outflow may alter myocardial development, resulting in progressive ventricular hypoplasia. Alteration of oxygen content may profoundly influence pulmonary vascular and ductus arteriosus responses. Interference in blood flow and oxygen content may affect cerebral development as a result of inadequate oxygen or energy substrate supply. The circulatory effects may be gestational dependent, related to maturation of vascular responses in different organs. These prenatal influences of congenital cardiac defects may severely affect immediate, as well as longterm, postnatal prognosis and survival. This has stimulated the development ...
TY - JOUR. T1 - Eligibility and Disqualification Recommendations for Competitive Athletes with Cardiovascular Abnormalities. T2 - Task Force 4: Congenital Heart Disease: A Scientific Statement from the American Heart Association and American College of Cardiology. AU - Van Hare, George F.. AU - Ackerman, Michael J.. AU - Evangelista, Juli Anne K. AU - Kovacs, Richard. AU - Myerburg, Robert J.. AU - Shafer, Keri M.. AU - Warnes, Carole A.. AU - Washington, Reginald L.. PY - 2015. Y1 - 2015. KW - ACC/AHA Scientific Statements. KW - athletes. KW - cardiovascular abnormalities. KW - congenital heart disease. KW - coronary vessel anomalies. KW - Fontan procedure. KW - transposition of great arteries. UR - http://www.scopus.com/inward/record.url?scp=84961055571&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=84961055571&partnerID=8YFLogxK. U2 - 10.1016/j.jacc.2015.09.036. DO - 10.1016/j.jacc.2015.09.036. M3 - Article. C2 - 26542660. AN - SCOPUS:84961055571. VL - 66. SP - ...
TY - JOUR. T1 - Cardiovascular abnormalities incidentally detected on helical CT pulmonary angiography. T2 - Spectrum of findings. AU - Gotway, Michael B.. AU - Nagai, Brian K.. AU - Dawn, Samuel K.. AU - Reddy, Gautham P.. AU - Araoz, Philip A.. AU - Webb, W. Richard. PY - 2001/11. Y1 - 2001/11. N2 - Helical CT pulmonary angiography (HCTPA) is being increasingly used for the investigation of suspected pulmonary embolism. Because HCTPA involves the use of thin collimation and high contrast injection rates and volumetric acquisitions, it is ideally suited for evaluating the thoracic vascular system and may reveal numerous cardiovascular abnormalities unrelated to venous thromboembolism. Such abnormalities include systemic venous anomalies, atrial and ventricular masses, structural and congenital lesions of the pulmonary arteries, structural abnormalities of the interatrial septum, aortic and pericardial abnormalities, and abnormalities of surgical conduits and bypass grafts. Awareness of the ...
aortic valve essay OBJECTIVE. Cardiac MDCT and cardiovascular MRI have become widely used for the evaluation of cardiovascular disease, including aortic valve disease. The purpose of this article is to present the cardiac MDCT and cardiovascular MRI findings of bicuspid aortic valve, its various complications, and other congenital cardiovascular malformations. Resume Writing Services Brisbane North! CONCLUSION. Radiologists should be aware of the clinical significance and the varied appearance of in research, bicuspid aortic valve at cardiac MDCT and cardiovascular MRI. Bicuspid aortic valve (BAV) is the most common congenital cardiovascular malformation, affecting approximately 0.5. Resume Writing Brisbane! 2% of the popu lation. BAV can coexist with other congenital cardiovascular malformations, particularly coarctation of the aorta (COA). New Cosmetologist Cover Letter! Patients with BAV are at increased risk of both valvular and vascular complications.. Serious valvular lesions include ...
The study is part of a randomized controlled trial comparing standard disease-modifying anti-rheumatic drugs (DMARDs) to anti-tumor necrosis factor (anti-TNF) therapy, Dr. Buch told Reuters Health.. Longitudinal evaluation with repeat cardiac MRI will allow us to answer whether the abnormalities we have reported improve, whether this depends on reduction in disease activity, and whether it matters how this is achieved, i.e., DMARD versus anti-TNF. We also wish to evaluate other parameters of cardiovascular health, including exercise capacity. This work is part of a wider program of research being conducted in the Leeds CARDIO-AID group, she said.. Epidemiological studies have shown that DMARD treatment reduces the risk of cardiovascular events in RA patients, while anti-TNF treatment is associated with a greater reduction in cardiovascular event risk, Dr. Buch said. Patients with established RA who have reduced disease activity also have lower risk of cardiovascular events, she added.. In ...
Gleason, Kerkhof, Cilia, Lanya, Finnoff, Sugimoto, Corrado Clin J Sport Medicine 2016; 0: 1-7 Sudden Cardiac Death (SCD) is estimated to occur between 1/40000 - 1/80000 of our young athletes. Although the incidence is uncommon, it remains a concern because the consequences are so tragic. So how should we screen our young athletes? This article…
A rare syndrome combining upper limb abnormalities and congenital heart diseases. In complete syndrome there is congenital cardiovascular malformations
RefSeq Summary (NM_001492): This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. Studies in rodents suggest that this protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis. The encoded protein is translated from a bicistronic mRNA that also encodes ceramide synthase 1. Mutations in this gene are associated with several congenital cardiovascular malformations. [provided by RefSeq, Jul 2016]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the ...
Cardiovascular malformations form the largest group of congenital anomalies, typically quoted at 0.8% of all live births. Several medicinal drugs have been proven to cause cardiovascular malformations. We discuss here the risks of the major known medications, including lithium, valproic acid,...
Patoma and colleagues have estimated the risk of cardiac malformations in children exposed to lithium during the first trimester of pregnancy.
Since fluoxetines release in the late 1980s, the use of antidepressants has increased steadily. Women of childbearing age make-up a significant proportion of users, so exposure during pregnancy is common. This is particularly true for early pregnancy exposure which often occurs before the woman knows she is pregnant. Estimates are that up to 13% of pregnancies will be exposed.1 The impact of these drugs on pregnancy outcomes has been a growing area of concern and debate.2 A major concern is whether the drugs are associated with congenital malformations. In their systematic review and … ...
What is the relationship between acute CNS events and cardiovascular abnormalities? CNS events can induce cardiac abnormalities in EKG morphology and rhythm. Most commonly, these abnormalities involve the T wave (diffuse, deep inversions). Minor ST segment elevation have also been reported in leads with abnormal T waves. T wave asymmetric, characteristic outward bulge in the…
Exercise is a common physiological stress used to elicit cardiovascular abnormalities not present at rest and to determine adequacy of cardiac function. Exercise ecg - one of the most frequent noninvasive modalities used to assess patients with suspected or proven cardiovascular disease. Estimate likelihood & extent of CAD , the prognosis , determine functional capacity & effects of therapy. Mainly used to estimate
Clinical trial for Heart Disease | Vascular Diseases | High Blood Pressure (Hypertension) | Cardiovascular Abnormalities | Diabetes and Hypertension , Men and Women ages 18 or older with High Blood Pressure and Diabetes Type 2 who DO NOT require the use of Insulin to control their Diabetes Levels
This classification of sports has been developed to allow a fundamental question to be addressed: whether it is reasonably safe to recommend that an athlete with a specific cardiovascular abnormality be eligible for a particular competitive sport (1,2). We recognize that cardiovascular disease assessments are imprecise and may change over time and be influenced by exercise training. Furthermore, there are potentially life-threatening aspects to the nature of the risk involved. We have attempted to incorporate these realities into the classification system.. Sports can be classified according to the type and intensity of exercise performed and also with regard to the danger of bodily injury from collision, as well as the consequences of syncope. Exercise can be divided into two broad types: dynamic (isotonic) and static (isometric) (3-6).. Dynamic exercise involves changes in muscle length and joint movement with rhythmic contractions that develop a relatively small intramuscular force; static ...
Results: Of the 38 ALL survivors, at least 1 adverse event occurred in 23 (60%), with 8 of them (21%) having multiple problems. Six (16%) of the survivors were obese and 8 (21%) of them were overweight. Subjects who were overweight or obese at the time of diagnosis were more likely to be overweight or obese at last follow-up. Obesity was more frequently determined in patients who were younger than 6 years of age at the time of diagnosis. Insulin resistance was observed in 8 (21%) subjects. Insulin resistance was more frequently seen in subjects who had family history of type 2 diabetes mellitus. Hyperlipidemia was detected in 8 (21%) patients. Hypothyroidism or premature thelarche were detected in 2 children. Two survivors had osteopenia. Cardiovascular abnormalities occurred in one of the subjects with hypertension and cardiac diastolic dysfunction ...
An initial autopsy of former Japanese finance minister Shoichi Nakagawa found cardiovascular abnormalities and alcohol in his body, but was unable to determine the cause of death, reports said on Monday.
Or you might want to embrace partners of the bridal get together. Try to include a protein source at each meal and snack throughout the day. My older sister, who also has Marfans, doesnt look proportionately unusual and, although being monitored by echocardiograms, does not present herself with the classic cardiovascular abnormalities; meaning all her cardiovascular measurements are currently within normal limits. Austrailian researchers recently discoverd that individuals who decreased fruit and vegetable consumption by 1 serving per day reported feeling rather more drained before, during, and after exercise classes. Best of all, theyre quite healthy, with anti-oxidant properties, and theyre loaded with bowl of salad nutrition like C, A, dog nutritionist nj E. 5 grams total fats per serving: Use the declaration zero grams for total fat. Moreover, in young adults, a high intact parathyroid hormone concentration was also found in Japan due to vitamin D insufficiency, duncan hines cupcakes ...
Great information by NEPAS: CURES - Cures are used in sausage products for color and flavor development as well as retarding the development of bacteria in the low temperature environment of...
Excellent case and Good work. Compliment you on your innovative thinking in the execution of a rather difficult third time redo operation. Signification points to high light: 1. Ability to do redo cases by single venous cannulation, if there is no intracardiac defect which needs attention. 2. Complete transection of the aorta to expose the bifurcation and pa branches, as this give unimpeded exposure and very good conditions to work on pa branches. 3, Division of aorta also gives excellent exposure for aortic valve repair. Prof.I.M.Rao and Dr.Anil Kumar, KIMS Hospital Hyderabad ...
CorMatrix Cardiovascular said today it won FDA 510(k) clearance for its Tyke biomaterial for use in neonates and infants.. The patch is designed to repair pericardial structures and as an epicardial covering or for intracardiac defects, septal defects, annulus repair, suture-line buttressing.. The Tyke is derived from the companys ECM technology platform and is composed of 2 layers of ECM, as opposed to 4 layers in their standard cardiac tissue repair patches, making it thinner for smaller repairs.. FDA clearance further validates CorMatrix ECM technology for creating world class implantable cardiac devices. CorMatrix is proud of this clearance achievement and the potential impact it can have on reducing CHD in children. This is but one small step in our ongoing quest to develop and deliver ideal materials for use in reconstructing damaged cardiac and vascular tissues. Tyke and other CorMatrix cardiac products will help us extend and improve the lives of those who receive our implants and move ...
The slip ring and nutate/rotate configuration of the new, fourth-generation, computed tomography (CT) (TCT-900S, Toshiba Medical Company) makes it possible to scan consecutively 25 slices every 75 s....
WSTF兔多克隆抗体(ab50850)可与小鼠, 人样本反应并经WB, IP实验严格验证,被2篇文献引用。所有产品均提供质保服务,中国75%以上现货。
TY - JOUR. T1 - Eligibility and Disqualification Recommendations for Competitive Athletes with Cardiovascular Abnormalities. T2 - Task Force 3: Hypertrophic Cardiomyopathy, Arrhythmogenic Right Ventricular Cardiomyopathy and Other Cardiomyopathies, and Myocarditis: A Scientific Statement from the American Heart Association and American College of Cardiology. AU - on behalf of the American Heart Association Electrocardiography and Arrhythmias Committee of the Council on Clinical Cardiology. AU - Council on Cardiovascular Disease in the Young. AU - Council on Cardiovascular and Stroke Nursing. AU - Council on Functional Genomics and Translational Biology. AU - American College of Cardiology. AU - Maron, Barry J.. AU - Udelson, James E.. AU - Bonow, Robert O.. AU - Nishimura, Rick A.. AU - Ackerman, Michael John. AU - Estes, N. A Mark. AU - Cooper, Leslie T Jr.. AU - Link, Mark S.. AU - Maron, Martin S.. PY - 2015/12/1. Y1 - 2015/12/1. KW - AHA Scientific Statements. KW - arrhythmogenic right ...
This study has shown a prevalence of cardiovascular anomalies in Downs syndrome of 42% in keeping with other published reports.8,-,10 Prevalence has remained relatively unchanged over time, although it does appear to be increasing in recent years. This may be due to improved diagnosis and the more widespread use of routine echocardiographic screening for infants with Downs syndrome.11 There has also been an increase in prenatal diagnosis of Downs syndrome,12 13 and the use of fetal echocardiography.14 15. The North East of England is well suited for population-based studies as it encompasses a well-defined geographical area with little cross-referral, reducing the risks of ascertainment bias. Data from our region have previously shown an increase in the prevalence of pregnancies affected by Downs syndrome and that, contrary to previous predictions, the prevalence of live born Downs syndrome has remained static, with a live birth prevalence of around 1.09 per 1000 live births.4 These babies ...
Chromosome 22q11.2 heterozygous deletions cause the most common deletion syndrome, including the DiGeorge syndrome phenotype. Using a mouse model of this deletion (named Df1) we show that the aortic arch patterning defects that occur in heterozygously deleted mice (Df1/+) are associated with a differentiation impairment of vascular smooth muscle in the 4th pharyngeal arch arteries (PAAs) during early embryogenesis. Using molecular markers for neural crest, endothelial cells and vascular smooth muscle, we show that cardiac neural crest migration into the 4th arch and initial formation of the 4th PAAs are apparently normal in Df1/+ embryos, but affected vessels are growth-impaired and do not acquire vascular smooth muscle. As in humans, not all deleted mice present with cardiovascular defects at birth. However, we found, unexpectedly, that all Df1/+ embryos have abnormally small 4th PAAs during early embryogenesis. Many embryos later overcome this early defect, coincident with the appearance of ...
Douglas P. Zipes, Mark S. Link, Michael J. Ackerman, Richard J. Kovacs, Robert J. Myerburg, N.A. Mark Estes and on behalf of the American Heart Association Electrocardiography and Arrhythmias Committee of the Council on Clinical Cardiology, Council on Cardiovascular Disease in the Young, Council on Cardiovascular and Stroke Nursing, Council on Functional Genomics and Translational Biology, and the American College of Cardiology ...
Double aortic arch is a relatively rare congenital cardiovascular malformation. Double aortic arch is an anomaly of the aortic arch in which two aortic arches form a complete vascular ring that can compress the trachea and/or esophagus. Embryologically, the aortas right sided 4th arch failed to r...
Background-Bicuspid aortic valve (BAV) is the most common congenital cardiovascular malformation (CVM). Although highly heritable, few causal variants have been identified. The purpose of this study was to identify genetic variants underlying BAV by whole exome sequencing (WES) a multiplex BAV kindred. Methods and Results-WES was performed on 17 individuals from a single family (BAV = 3, other CVM = 3). Post variant calling error control metrics (ECM) were established after examining the relationship between Mendelian inheritance error rate and coverage, quality score, and call rate. To determine the most effective approach to identifying susceptibility variants from among 54,674 variants passing ECM, we evaluated three variant selection strategies frequently used in WES studies plus extended family linkage. No putative rare, high impact variants were identified in all affected but no unaffected individuals. Eight high impact variants were identified by at least two of the commonly used ...
To the Editor: Williams-Beuren Syndrome (WBS) is a rare neurodevelopmental disorder caused by deletion of chromosome 7 at q11.23. It is characterized by distinctive facies, congenital cardiovascular malformations, intellectual ...
To the Editor: Williams-Beuren Syndrome (WBS) is a rare neurodevelopmental disorder caused by deletion of chromosome 7 at q11.23. It is characterized by distinctive facies, congenital cardiovascular malformations, intellectual ...
Barium swallow reveals fixed narrowing of the oesophagus at the level of the aortic arch without mucosal abnormality. The narrowing runs oblique from inferior left to superior right and involves the posterior aspect of the oesophagus. This is c...
In lecture 7 - Early Vascular Development, there was an introduction to the origins of the cardiovascular system. This second lecture will now focus on the extensive remodeling that occurs in both the heart and vascular system during later development. In addition, there will be discussion on the major cardiovascular abnormalities. The laboratory this week will also give you the opportunity to work through some of these concepts using a new online teaching module. ...
Exercise is a common physiology stress used to elicit cardiovascular abnormalities not present at rest and to determine the adequacy of cardiac function. Tread Mill Test (TMT) is one of the most frequent non invasive modalities used to assess patients with suspected or proven CAD. The test is mainly used to estimate prognosis and to determine functional capacity, the likelihood and extent of CAD, and the effects of therapy. The treadmill protocol should be consistent with the patients physical capacity and the purpose of the test. The Bruce multistage maximal treadmill protocol has 3-minute periods to allow achievement of a steady state before work-load is increased. In older individuals or those whose exercise capacity is limited by Cardiac Disease, the protocol can be modified by two 3-minute warm-up stages. The sensitivity of the Tread Mill Test (TMT) in patients with CAD is approximately 68%, and specificity is 77%. The exercise electrocardiography (ECG) result is more likely to be abnormal ...
Intake of garlic has been reported earlier to reduce blood pressure and improve cardiovascular abnormalities, and many studies thereafter explored the cardioprotective properties of garlic[11, 12]. These new findings resulted in an increase in demand for garlic products in the market and encouraged the development of wide varieties of garlic with better quality and which would be grown more efficiently. In this study, we used extracts from a variety of hard necked Rocambole purple garlic developed locally in Manitoba, Canada. This new garlic variety is better adapted to harsh climate and has superior disease resistance qualities. In general, the purple garlic has a colored skin which possibly indicates the presence of a different set of bioactive compounds when compared to the normal variety of garlic with white skin. Furthermore, no study has explored the medicinal properties of garlic skin in any form. Accordingly, in this study we used skin and flesh extracts from a purple variety of garlic ...
(HealthDay) -- Regardless of exposure to cardiotoxic cancer therapies, survivors of childhood cancers display cardiovascular abnormalities and have markers of increased systemic inflammation and atherosclerotic disease, according ...
Aberrant right subclavian artery (ARSA), also called lusorian artery, is a well known anatomical variant of the origin of the right subclavian artery, one of the most common congenital vascular abnormalities of the aortic arch (the prevalence among the population is 1-2% in according to different authors) [1-4]. Usually ARSA arises after the left subclavian artery and crosses the mediastinum behind the oesophagus and the trachea. For its particular position ARSA can cause compression to the close anatomical structures. Dysphagia lusoria is the most frequent symptom (in 10 % of cases). For the same reason the prolonged compression caused by medical devices such as nasogastric or endotracheal tubes on the arterial wall of the ARSA can cause severe injury, especially when an ARSA aneurysm is present. In rare cases it can lead up to an oesophageal fistula with profuse bleeding characterised by high mortality rate (till now less than 20 cases were reported in literature). In our case fistulisation ...
homeostasis, and disease. Cell. 2009 Apr 3;137(1):32-45.. Goldstein B, Macara IG. The PAR proteins: fundamental players in animal cell polarization. Dev Cell. 2007 Nov;13(5):609-22.. Hamblet NS, Lijam N, Ruiz-Lozano P, Wang J, Yang Y, Luo Z, Mei L, Chien KR, Sussman DJ, Wynshaw-Boris A. Dishevelled 2 is essential for cardiac outflow tract development, somite segmentation and neural tube closure. Development. 2002 Dec;129(24):5827-38.. Heasman SJ, Ridley AJ. Mammalian Rho GTPases: new insights into their functions from in vivo studies. Nat Rev Mol Cell Biol. 2008 Sep;9(9):690-701.. Henderson DJ, Conway SJ, Greene ND, Gerrelli D, Murdoch JN, Anderson RH, Copp AJ. Cardiovascular defects associated with abnormalities in midline development in the Loop-tail mouse mutant. Circ Res. 2001 Jul 6;89(1):6-12.. Henderson DJ, Anderson RH. The development and structure of the ventricles in the human heart. Pediatr Cardiol. 2009 Jul;30(5):588-96.. Hildreth V, Webb S, Chaudhry B, Peat JD, Phillips HM, Brown N, ...
FUNCTION: This gene encodes a member of the endothelin family of peptides. The encoded preproprotein undergoes proteolytic processing to generate a peptide before secretion by the vascular endothelial cells. The mature peptide has various biological activities such as vasoconstriction, cell proliferation, stimulation of hormone release and modulation of central nervous activity. Mice lacking the encoded protein exhibit neonatal lethality accompanied with numerous craniofacial and cardiovascular defects due to disruption in cranial and cardiac neural crest cell patterning during early embryogenesis. [provided by RefSeq, Feb 2016 ...
Coarctation of the aorta is a common congenital cardiovascular defect characterized by upper-body hypertension resulting from constriction of the aorta. Constrictions vary in degree; they may occur at any point from the transverse arch to the iliac bifurcation.
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There is currently a deficiency in understanding the events that effect proper cardiovascular development. The long-term goal is to define these events in molec...
Learn about the causes, symptoms, diagnosis & treatment of Congenital Cardiovascular Anomalies from the Professional Version of the Merck Manuals.
INTRODUCTION: Floating thrombus in an aberrant right subclavian artery is a rare cause of peripheral arterial embolic events. CASE REPORT: We report a 45-year-old woman who presented with an ischemia of the right superior limb from embolic event. The diagnosis of mobile thrombus in an aberrant right subclavian artery was obtained with transoesophageal echocardiography and computed tomography. After three weeks of oral anticoagulant therapy, there was no significant resolution of the thrombus, and a surgical treatment was performed to prevent further embolization. The surgical procedure consisted of thrombectomy and reimplantation of the aberrant right subclavian artery to the right carotid artery. Postoperative recovery was uneventful. CONCLUSION: This case report illustrates that transoesophageal echography and computed tomography are useful to detect mobile thrombus of the thoracic aorta and is warranted in any embolic event in young patients.
A 57 yo male with a background history of common variable Immunodeficiency syndrome (CVID) on Immunoglobulin Infusion (Kiovig) 40mg three weekly was referred for investigation of diarrhoea and follow up from previous history of colonic polyps.Colonoscopy showed an irregular looking ileocaecal valve (ICV) with an adjacent flat polyp (Paris IIa). Biopsies showed low grade dysplasia. There was also a duodenal polyp noted on gastroscopy and biopsy again showed low grade dysplasia. In light of the findings of upper and lower gastrointestinal tract polyps, a small bowel capsule endoscopy (SBCE) was arranged. This showed an irregular area of mucosa in the proximal small bowel with significant ulceration and inflammation (Figure 1). There were also multiple scattered lymphagiectasias and lymphoid hyperplasia in the distal small bowel (Figure 2).Anterograde double ballon enteroscopy (ADBE) was subsequently performed to the distal jejunum about 8 weeks after the SBCE. The duodenal polyp seen at gastroscopy was
Details of the image Dysphagia lusoria from aberrant left subclavian artery with Kommerell diverticulum Modality: Fluoroscopy (Frontal)
A two-year-old Border Collie presented with a three-month history of regurgitation. Investigation with plain radiography, digital fluoroscopy, endoscopy and CT angiography (CTA) confirmed the presence of an aberrant right subclavian artery causing dorsal oesophageal compression. In this report, CTA was used to depict the anatomy of an aberrant right subclavian vessel and to highlight the importance of this imaging modality to identify the structures involved in a vascular ring. This report also identifies a patient with a congenital vascular ring anomaly presenting with adult-onset regurgitation, which has been successfully managed with medical treatment. ...
BAV is one of the most common congenital cardiovascular malformations, with an estimated incidence of 1% to 2%.25 An echocardiographic survey of primary school children demonstrated a BAV prevalence of 0.75% in males and 0.24% in females.26 The true prevalence of BAV in newborns was determined in a recent study of 1075 neonates screened by echocardiography.27 BAV was identified in a prevalence of 4.6 per 1000 live births. The prevalence of BAV by sex was 7.1/1000 in male neonates and 1.9/1000 in female neonates. BAV is sometimes inherited, and family clusters have been studied. Inheritance patterns are autosomal dominant with variable penetrance.28,29 Prevalence among asymptomatic family members of patients with BAV was 37% by echocardiographic screening. First-degree relatives of patients with various types of LVOTO are at an increased risk of having BAV compared with the general population.30. BAVs arise from abnormal valvulogenesis and cusp formation, resulting in the formation of 1 smaller ...
TY - JOUR. T1 - Arteria Lusoria. AU - Knollmann, Friedrich D. AU - Hammerschmidt, R.. PY - 2003/10. Y1 - 2003/10. N2 - An aberrant right subclavian artery (Arteria lusoria) is not an uncommon anatomic variant and plays an important role in the preoperative planning of aortic surgery patients. The diagnosis can be conveniently established by computed tomography.. AB - An aberrant right subclavian artery (Arteria lusoria) is not an uncommon anatomic variant and plays an important role in the preoperative planning of aortic surgery patients. The diagnosis can be conveniently established by computed tomography.. KW - Abnomalities. KW - Aorta. KW - Arteries. KW - Computed tomography. UR - http://www.scopus.com/inward/record.url?scp=0345307758&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0345307758&partnerID=8YFLogxK. U2 - 10.1007/s00398-003-0408-y. DO - 10.1007/s00398-003-0408-y. M3 - Article. AN - SCOPUS:0345307758. VL - 17. SP - 230. EP - 231. JO - Zeitschrift fur Herz-, ...
TY - JOUR. T1 - Heterotaxia syndrome. T2 - The role of screening for intestinal rotation abnormalities. AU - Choi, M.. AU - Borenstein, S. H.. AU - Hornberger, L.. AU - Langer, J. C.. PY - 2005/8. Y1 - 2005/8. N2 - Background: Heterotaxia syndrome involves multiple anomalies, including cardiac malformations and intestinal rotation abnormalities. Most authors recommend routine radiological evaluation, with laparotomy and Ladd procedure if a rotation abnormality is found. Aims: To determine if routine radiological screening is necessary, and if there is a group of children that can safely be managed expectantly. Methods: Retrospective chart review of all children with heterotaxia syndrome from 1968 to 2002. Results: Complete data were available for 177 patients. Twenty five (14%) had neonatal gastrointestinal symptoms (feeding intolerance, vomiting). Eleven of these had gastrointestinal contrast studies, of which seven were abnormal and led to surgery. Of the 152 asymptomatic neonates, nine had ...
Deletion of the transcriptional modulator Cited2 in the mouse results in embryonic lethality, cardiovascular malformations, adrenal agenesis, cranial ganglia fusion, exencephaly, and left-right patterning defects, all seen with a varying degree of penetrance. The phenotypic heterogeneity, observed on different genetic backgrounds, indicates the existence of both genetic and environmental modifiers. Mice lacking the LIM domain-containing protein Lmo4 share specific phenotypes with Cited2 null embryos, such as embryonic lethality, cranial ganglia fusion, and exencephaly. These shared phenotypes suggested that Lmo4 may be a potential genetic modifier of the Cited2 phenotype. Examination of Lmo4-deficient embryos revealed partially penetrant cardiovascular malformations and hypoplastic thymus. Examination of Lmo4;Cited2 compound mutants indicated that there is a genetic interaction between Cited2 and Lmo4 in control of thymus development. Our data suggest that this may occur, in part, through control of
Williams syndrome is a multisystemic rare genetic disorder that was first described in 1961, by a cardiologist from New Zealand. Williams syndrome is caused by a deletion of 26-28 genes in the long arm of chromosome 7 at 7q11.23. The deletion occurs at the time of conception. It is characterized by a number of developmental and physical abnormalities including congenital cardiovascular abnormalities, mental retardation, neurological features, growth deficiency, genitourinary manifestations, gastrointestinal problems, musculoskeletal problems, unique behavioral characteristics, and dental problems. ...
Failure to visualize the fetal bladder can be due to renal abnormalities or bladder exstrophy (,,, Fig 23). Cardiomyopathies can be broadly classified as dilated, hypertrophic, and restrictive types. There are 2 types of polydactyly: Postaxial (more common): sixth digit is on the ulnar or fibular side, after the fifth digit. 44, No. The etiology of fetal limb abnormalities is very complex, involving different risk factors: chromosomal abnormalities, gene disorders, intrauterine factors, maternal diseases, or exposure to different risk factors. JMAJ, November 2001-Vol. Intrinsic causes of (Achiron R, Achiron A: Transvaginal ultrasonic assessment of the early fetal brain. Cardiomyopathies account for 8-11% of fetal cardiovascular abnormalities with one third of fetuses dying in utero []. The genetic etiology of non-aneuploid fetal structural abnormalities is typically investigated by karyotyping and array-based detection of microscopically detectable rearrangements, and submicroscopic copy-number ...
The American Heart Association (AHA) and American College of Cardiology (ACC) have provided recommendations regarding eligibility and disqualification of competitive athletes with cardiovascular abnormalities.
TY - JOUR. T1 - Sindrome serotoninergica. T2 - Perché anche il cardiologo la dovrebbe conoscere (e temere). AU - Temporelli, Pier Luigi. AU - Boccanelli, Alessandro. AU - Desideri, Giovambattista. AU - Faggiano, Pompilio. AU - Mora, Gabriele. AU - Oliva, Fabrizio. AU - Terrosu, Pierfranco. PY - 2015/1/1. Y1 - 2015/1/1. N2 - The serotonin syndrome (SS) represents a life-threatening adverse drug reaction, caused by serotonin overload in the central and peripheral nervous system, producing autonomic instability, neuromuscular and cardiovascular abnormalities, and cognitive alterations. The incidence of SS has been growing over the last few years, as a consequence of population aging and the steadily increasing use of pro-serotoninergic agents in clinical practice, in the presence of various comorbidities, mainly cardiovascular. Cardiologists often use combination therapies including serotoninergic agents, and should therefore consider the risk of serotoninergic adverse events caused by ...
It is suggested to measure PVi in the same body position, remaining still and without talking, at the same breathing rate and depth of breathing, until you see a high confidence PVi value (displayed value is bright, not dim). An increase in PVi may indicate a decreased level of hydration, increased breathing effort, or other factors. A decrease in PVi may indicate an increased level of hydration, decreased breathing effort, or other factors. Multiple factors other than hydration and breathing effort can affect PVi, including breathing rate, depth of breathing, body position, body movement, vascular tone, blood flow to the finger (perfusion index), normal variation within a short-term monitoring session, waveform shape changes, and/or cardiovascular abnormalities. ...
Thirty-eight patients who presented with diabetes and a changed state of consciousness satisfied the criteria for lactic acidosis. Sixteen patients were non-ketotic, and 15 of these were receiving phenformin on admission. In all but one of these 15 patients, however, additional renal or cardiovascular abnormalities, or both, could be identified, which supported a multifactorial aetiology for lactic acidosis. Advanced age and cardiovascular and renal disease are absolute contraindications to the use of phenformin in diabetics. ...
Dysphagia lusoria is a well documented complication of variant aortic arch anatomy. Typically it is associated with an aberrant right subclavian artery causing dysphagia by compression. The word lusoria originates from the Latin origin lusus naturae, meaning freak of nature. Dysphagia as a result of tortuous and ectatic anatomy of the carotid vessels is rare. We have identified a few similar cases, including one from 2010 1, which describes a medially coursing left internal carotid artery resulting in difficulty swallowing. It appears that dysphagia, as a result of common carotid ectasia is even rarer, with only a couple of cases appearing in literature2 ...
TY - JOUR. T1 - Loss of function of the Prx1 and Prx2 hameobox genes alters architecture of the great elastic arteries and ductus arteriosus. AU - Bergwerff, Maarten. AU - Gittenberger-de Groot, Adriana C.. AU - Wisse, Lambertus J.. AU - DeRuiter, Marco C.. AU - Wessels, Andy. AU - Martin, James F.. AU - Olson, Eric N.. AU - Kern, Michael J.. PY - 2000. Y1 - 2000. N2 - Prx1 (MHox) and Prx2 (S8) are non-clustered homeobox genes that are expressed in a complex, mostly mesenchyme-specific pattern throughout embryogenesis. The expression pattern and gene-targeted mice previously revealed a major role for Prx1 in skeletogenesis. In addition, specific and high expression of both Prx genes was reported in the developing cardiovascular system, predominantly in prospective connective tissues of the heart and in the great arteries and veins. We examined embryos of previously generated gene-targeted mice. Prx2-/- mutants were viable and did not show cardiovascular malformations. Intracardiac morphology of ...
Searching through the biomedical literature, I looked at four major categories of caffeine effects on the developing fetus. The first category, major birth defects, was easy to evaluate. Very high levels of caffeine have been shown to cause birth defects in animals (Nehlig & Debry 1994), but the levels at which these effects are seen are so high that they would not practically apply to even staunchly caffeine-addicted humans. To assess whether caffeine has these kinds of effects in humans, epidemiological studies (studies of populations of humans) must be used. In a systematic review of the epidemiological literature on cardiovascular malformations and oral clefts (Browne 2006), no evidence was found that caffeine alone was teratogenic for humans. [Caffeine has, however, been found to increase the risk of birth defects by other substances, such as tobacco and alcohol (Nehlig & Debry 1994)]. In a review of several animal studies and epidemiological studies exploring birth defects in general, ...
The formation and transformation of the pharyngeal arch arteries in the mouse embryo, from 8.5 to 13 days of gestation (DG), was observed using scanning electron microscopy of vascular casts and graphic reconstruction of 1-microm serial epoxy-resin sections. Late in 8.5-9DG (12 somites), the paired …
a Four branches arises from the aortic arch. Aberrant right subclavian artery(ARSA) marked by astrex. b ARSA arises distal to left subclavian artery. c Obstruct
CT examination of the chest with IV contrast performed accoring to a PE/DVT protocol demonstrated an aberrant right subclavian artery. The mediastinum was othe
The use of amphetamines is associated with an increase in cardiovascular defects in babies. Barbiturate use during pregnancy may be linked to birth defects, withdrawals, poor feeding, and seizures. Opiods are associated with abnormalities and complications during pregnancy.
The use of amphetamines is associated with an increase in cardiovascular defects in babies. Barbiturate use during pregnancy may be linked to birth defects, withdrawals, poor feeding, and seizures. Opiods are associated with abnormalities and complications during pregnancy.
Learn about the causes, symptoms, diagnosis & treatment of Congenital Cardiovascular Anomalies from the Professional Version of the Merck Manuals.
Small molecule microribonucleic acids (miRNAs) are coming up with a huge impact on the scientific world of therapeutics and diagnostics
On January 10, 2011 my son, Noah, passed away from complications related to Heterotaxy Syndrome. He was just 32 days old. Life has been pretty rough for me and my husband since then. Counselors, spiritual leaders and other bereaved parents advised us that losing a child is one of the worst things a person can…
"Classic imaging signs of congenital cardiovascular abnormalities". Radiographics. 27 (5): 1323-34. doi:10.1148/rg.275065148. ...
Some individual with Adie syndrome may also have cardiovascular abnormalities.[4] Pathophysiology[edit]. Pupillary symptoms of ... and abnormalities of sweating.[1] Other signs may include hyperopia due to accommodative paresis, photophobia and difficulty ...
Input to the cardiovascular centres[edit]. The cardiovascular centres receive input from a series of visceral receptors with ... Arrhythmias are abnormalities of the heart rate and rhythm (sometimes felt as palpitations). They can be divided into two broad ... Correlation with cardiovascular mortality risk[edit]. This section needs more medical references for verification or relies too ... Cardiovascular centres[edit]. The heart rate is rhythmically generated by the sinoatrial node. It is also influenced by central ...
Cardiovascular: Raynaud's phenomenon (is the presenting symptom in 30% of affected persons, occurs in 95% of affected ... irregular heart rate and fainting due to conduction abnormalities, hypertension, and congestive heart failure ... "Cardiovascular disease in systemic sclerosis--an emerging association?". Arthritis Research & Therapy. 13 (4): 237. doi: ...
"Cardiovascular abnormalities in autosomal-dominant polycystic kidney disease". Nature Reviews Nephrology. 5 (4): 221-28. doi: ... Because of the ubiquity of arsenic in ground water supplies and its effect on cardiovascular health, low dose arsenic poisoning ... Mackenzie IS, Rutherford D, MacDonald TM (2008). "Nitric oxide and cardiovascular effects: new insights in the role of nitric ... Pack AI, Gislason T (2009). "Obstructive sleep apnea and cardiovascular disease: a perspective and future directions". Progress ...
van den Hoff MJ, Moorma AF (2000). "Cardiac neural crest: the holy grail of cardiac abnormalities?". Cardiovascular Research. ... Abu-Issa R, Smyth G, Smoak I, Yamamura K, Meyers EN (2002). "Fgf8 is required for pharyngeal arch and cardiovascular ... Abu-Issa R. et al "FGF8 is required for pharyngeal arch and cardiovascular development in the mouse." Development October 2012 ... Lepore J. J. et al "GATA-6 regulates semaphorin 3C and is required in cardiac neural crest for cardiovascular morphogenesis." ...
Other abnormalities included near to complete dissociation of intercalated discs and inflammation, and eventual arrhythmogenic ... Cardiovascular Research. 104 (2): 245-57. doi:10.1093/cvr/cvu206. PMID 25213555. Kant S, Krull P, Eisner S, Leube RE, Krusche ... Cardiovascular Research. 95 (4): 409-18. doi:10.1093/cvr/cvs219. PMID 22764152. Kant S, Holthöfer B, Magin TM, Krusche CA, ... "Intercalated disc abnormalities, reduced Na(+) current density, and conduction slowing in desmoglein-2 mutant mice prior to ...
"Congenital cardiovascular malformations associated with chromosome abnormalities: An epidemiologic study". The Journal of ... She contributed to many of the early articles on surgical procedures for pediatric cardiac abnormalities and early descriptive ... Developments in Cardiovascular Medicine). Springer Science & Business Media. ISBN 978-0792333753. Neill, Catherine A.; Clark, ... publications on cholesterol abnormalities among pediatric patients. Neill discovered and named scimitar syndrome, in which ...
... cardiovascular, and hematological abnormalities". Genes & Development. 8 (16): 1875-87. doi:10.1101/gad.8.16.1875. PMID 7958863 ... Other genetic abnormalities in PDGFRB lead to various forms of potentially malignant bone marrow disorders: small deletions in ... contributes to endemic diseases such as cancer and cardiovascular disease. Human chromosome 5 deletions that remove three ...
... cardiovascular, and hematological abnormalities". Genes & Development. 8 (16): 1875-1887. doi:10.1101/gad.8.16.1875. ISSN 0890- ...
Experimental mice without the endoglin gene die due to cardiovascular abnormalities. In humans endoglin may be involved in the ... Endoglin has a role in the development of the cardiovascular system and in vascular remodeling. Its expression is regulated ...
The abnormal development of the foetus' lungs leads to cardiovascular abnormalities. Distention of the lungs results in a ...
Cardiovascular abnormalities include ventricular septal defect and coarctation of the aorta; urinary system issues include ... The major ocular abnormalities are colobomas and choristomas. Skeletal abnormalities may include dental irregularities, ... of cases structural abnormality of cerebrum or cranium in 72% of cases The major neurological abnormalities include mental ... The abnormalities may occur in a variety of combinations, and need not include all three aspects of the classic triad of ...
Irving, Claire A.; Chaudhari, Milind P. (April 2012). "Cardiovascular abnormalities in Down's syndrome: spectrum, management ... There was a clear abnormality not only in the atrioventricular canal but also in the left ventricle. This study supports the ... portion of the ventricles and this is associated with a significant abnormality of the valves separating the atria from the ... but it also occurs as an isolated abnormality.[citation needed] Treatment is surgical and involves closure of the atrial and ...
Abnormalities in this system occur in relatively rare genetic diseases such as Long QT syndrome, Brugada syndrome, and ... Congenital cardiovascular deaths are reported to occur disproportionately in African-American athletes. After age 35, acquired ... Before age 35, congenital abnormalities of the heart and blood vessels predominate. These are usually asymptomatic prior to the ... Consequently, autopsy-negative sudden cardiac deaths (no physical abnormalities identified) may comprise a larger part of the ...
... can also cause a variety of cardiovascular and orthopedic abnormalities. This rare disorder is caused by a ... Liang, C.D., Hang, C.L. " Elongation of the Aorta and Multiple Cardiovascular Abnormalities Associated with Larsen Syndrome." ... "Cardiovascular Manifestations in the Larsen Syndrome." Pediatrics. 71.6 (1983): 942-946. Print. Johnston, C.E., Birch, J.G., ... It is reasonable to believe that the joint abnormalities and cardiac anomalies associated with Larsen syndrome are related to ...
"Electrocardiographic abnormalities in acute cerebrovascular events in patients with/without cardiovascular disease". Annals of ... X. ST Segment Abnormalities Frank G. Yanowitz, MD. University of Utah School of Medicine madscientist software > MicroEKG ... The International Journal of Cardiovascular Imaging. 21 (2-3): 253-8, discussion 259-60. doi:10.1007/s10554-004-2458-y. PMID ... "Computerized ST depression analysis improves prediction of all-cause and cardiovascular mortality: the strong heart study". ...
Cardiovascular abnormalities such as QRS complex widening and QT interval prolongation may also occur. Treatment ... Reported blood abnormalities with its use include lymphopenia, eosinophilia, and atypical lymphocytosis. For short-term ... and mortality from cardiovascular causes. Care should be taken if combined with medication altering liver function as well as ...
... and cardiovascular disease. BFR is also associated with certain metabolic abnormalities such as elevations of plasma sugar and ...
... or lipid panel is a panel of blood tests that serves as an initial broad medical screening tool for abnormalities ... "Pediatric Cardiovascular Risk Reduction Guidelines - NHLBI, NIH". Archived from the original on 2012-11-16. Sidhu, D.; Naugler ... For healthy adults with no cardiovascular risk factors, the ATP III guidelines recommend screening once every five years. A ... The results of this test can identify certain genetic diseases and can determine approximate risks for cardiovascular disease, ...
In the Cardiovascular Health Study, a population study conducted among 3,660 adults over the age of 65. 31% showed evidence of ... A finding of elevated TCD ultrasonographic velocity warrants MRI of the brain, as those with both abnormalities who are not ... The Cardiovascular Health Study. CHS Collaborative Research Group". Stroke. 28 (6): 1158-64. doi:10.1161/01.STR.28.6.1158. PMID ... 1991). "The Cardiovascular Health Study: Design and rationale". Annals of Epidemiology. 1 (3): 263-76. doi:10.1016/1047-2797(91 ...
When an individual has inherited an abnormality it is usually present in all of their cells. However some mutations like DNA ... Additionally, LOY is associated with greater risk for Alzheimer's disease and cardiovascular disease. Smoking increases the ... Trisomy 21 (Down Syndrome) is one of the most prevalent chromosomal abnormalities amongst live births. Of all trisomy 21 ... Cardiovascular Genetics. 10 (4): e001544. doi:10.1161/circgenetics.116.001544. ISSN 1942-325X. PMID 28768751. Dumanski, Jan P ...
Air pollution and cardiovascular disease: a statement for healthcare professionals from the Expert Panel on Population and ... An 82-year-old man with dyspnea and pulmonary abnormalities. N Engl J Med. 2003 Apr 17;348(16):1574-85. Meadors M, Floyd J, ... Long-term exposure to air pollution and incidence of cardiovascular events in women. N Engl J Med. 2007 Feb 1;356(5):447-58. ... The data showed that particulate matter can be a major cause of cardiovascular disease, and can also cause pulmonary toxicity. ...
CT angiography began to replace conventional angiography in diagnosing and characterizing most cardiovascular abnormalities. ... a transformation in cardiovascular disease characterization continues to advance". Radiology. 271 (3): 633-52. doi:10.1148/ ...
... is a spectrum of congenital abnormalities of the thumb varying from small defects to complete absence of the ... Embryological hand development occurs simultaneously with growth and development of the cardiovascular, neurologic and ... A syndrome is a combination of three or more abnormalities. Examples of syndromes with an hypoplastic thumb are Holt-Oram ... The cause is unknown, and likely related to genetic abnormalities. Children with Fanconi anemia can sometimes display ...
Direct fatalities in sport are rare, as most sport fatalities are indirect and associated with non-sport cardiovascular ... Fatal injury may reveal an unknown "underlying anatomical or physiological abnormality". Individuals with certain anatomical ... These include cardiovascular complications, such as deep vein thrombosis, pulmonary embolism, orthostatic hypotension, ... Indirect fatalities are usually caused by cardiovascular conditions, such as hypertrophic cardiomyopathy and coronary artery ...
His other areas of research include cardiovascular risk factors, bone-mineral metabolism, metabolic abnormalities and race- ...
In the remainder, it is usually associated with cardiovascular or kidney abnormalities, including coarctation of the aorta. Two ... This abnormality is a relatively rare congenital heart disease in the general population. The prevalence of this abnormality ... Different karyotypes may have differing rates of cardiovascular malformations. Two studies found a rate of cardiovascular ... The chromosomal abnormality may be present in just some cells in which case it is known as TS with mosaicism. In these cases, ...
... cardiovascular outcomes and adverse events in patients with diabetes and cardiovascular disease or risk: A systematic review ... There are a number of rare cases of diabetes that arise due to an abnormality in a single gene (known as monogenic forms of ... The use of aspirin to prevent cardiovascular disease in diabetes is controversial.[114] Aspirin is recommended in people at ... Chen X, Yang L, Zhai SD (December 2012). "Risk of cardiovascular disease and all-cause mortality among diabetic patients ...
The physician spreads the buttocks apart and will usually examine the external area (anus and perineum) for any abnormalities ... Cardiovascular. *Cardiac examination. *Peripheral vascular examination. *Heart sounds. *Other *Abdominojugular test. *Ankle- ...
Fareed M, Afzal M (April 2016). "Increased cardiovascular risks associated with familial inbreeding: a population-based study ... like the vertebral column of wolves on Isle Royale or having cranial abnormalities, such as in Northern elephant seals, where ...
This gene seems to pleiotropically lead to other abnormalities like increased metabolism, higher food consumption, accelerated ... cardiovascular, and nervous system, as well as the eyes and lungs.[36] ... of known causes of death in diagnosed patients relating to cardiovascular complications and congestive cardiac failure. Other ...
Huang, G; Coviello, A. Clinical update on screening, diagnosis and management of metabolic disorders and cardiovascular risk ... Clinical features, hormonal profile, and metabolic abnormalities of obese women with obese polycystic ovary syndrome]. Zhonghua ... Mather KJ, Kwan F, Corenblum B. Hyperinsulinemia in polycystic ovary syndrome correlates with increased cardiovascular risk ...
... "some fetal abnormalities", the woman "would have an abortion", to avoid an increase in the infant mortality rate.[79] ... cardiovascular disease and all-cause mortality have been related to sustained population-wide weight loss as a result of ... notes that pregnant women may be forced to undergo abortions if fetal abnormalities are detected or forcibly placed under ...
Stroke and other cardiovascular disease are related to OSA and those under the age of 70 have an increased risk of early death. ... The operation may be far from trivial, especially in the worst apnea cases, in which growth is retarded and abnormalities of ... Without treatment, the sleep deprivation and lack of oxygen caused by sleep apnea increases health risks such as cardiovascular ... In this chromosomal abnormality, several features combine to make the presence of obstructive sleep apnea more likely. The ...
Congenital malformations, deformations and chromosomal abnormalities XVIII R00-R99 Symptoms, signs and abnormal clinical and ...
... genetic studies have shown that a common abnormality in the prothrombin gene (G20210A) increases the risk of cardiovascular ... Abnormalities in the ARH gene, also known as LDLRAP1, were first reported in a family in 1973.[14] In contrast to the other ... Cardiovascular diseaseEdit. Accelerated deposition of cholesterol in the walls of arteries leads to atherosclerosis, the ... A single abnormal copy (heterozygote) of FH causes cardiovascular disease by the age of 50 in about 40% of cases. Having two ...
... fluid repletion to correct electrolyte abnormalities and third-space losses, support for blood pressure, parenteral nutrition,[ ... Cardiovascular. *Pneumopericardium. *Persistent fetal circulation. Haemorrhagic and. hematologic disease. *Vitamin K deficiency ...
Specific abnormalities in the NCV results may suggest, for example, that the person has a form of peripheral neuropathy (damage ... improve cardiovascular health, and help people fight fatigue and depression. Range of motion and stretching exercises can help ...
C-type natriuretic peptide (CNP) has been shown to exert a variety of cardiovascular effects including vasodilation and ... endothelial abnormalities associated with pathogenesis of certain diseases. It is widely accepted EDHF plays an important role ... CNP is widely distributed in the cardiovascular system and it has been found at high concentrations, in particular in ... Moreover, depending on the type of cardiovascular disorders altered, EDHF responses may contribute to, or compensate for, ...
Mahmood SS (2016). "Cardiovascular Complications of Cranial and Neck Radiation". Current Treatment Options in Cardiovascular ... However, double-stranded DNA breaks are much more difficult to repair, and can lead to dramatic chromosomal abnormalities and ... Cardiovascular disease. Radiation can increase the risk of heart disease and death as observed in previous breast cancer RT ... Cardiovascular late side effects have been termed radiation-induced heart disease (RIHD) and radiation-induced vascular disease ...
... age-related mitochondrial abnormalities; and preserved muscle stem cell function.[55] Muscle tissue grows when stimulated, so ... cardiovascular disease causes.[14] The authors attempted to adjust for confounding factors (cigarette smoking, failure to ... "Calorie restriction limits the generation but not the progression of mitochondrial abnormalities in aging skeletal muscle". ...
There are no obvious abnormalities in the male accessory glands, including the prostate gland, bulbourethral glands, ... GPER knockout mice have also been generated, and exhibit obesity, cardiovascular dysfunction, insulin resistance, glucose ...
Beckwith-Wiedemann syndrome is also associated with genomic imprinting, often caused by abnormalities in maternal genomic ... of Swedish men who were exposed during preadolescence to famine in the 19th century were less likely to die of cardiovascular ... "Potential Diagnostic and Prognostic Biomarkers of Epigenetic Drift within the Cardiovascular Compartment". BioMed Research ...
Less typical side effects are those of the cardiovascular system, such as high blood pressure, various types of arrhythmia, and ... liver function tests abnormalities, hallucinations and heart attack, and the benefit in PD disappeared at follow up after drug ... with liver problems which involves recommendation of lower starting dose and monitoring of any hepatic function abnormalities.[ ...
2007). "Insulin resistance and inflammation as precursors of frailty: the Cardiovascular Health Study". Arch Intern Med. 167 (7 ... hormonal abnormalities,[8] obesity,[9] hypovitaminosis D in men,[10] and environment-related factors such as life space and ... Frailty more than doubles the risk of morbidity and mortality from surgery and cardiovascular conditions.[33] Assessment of ... Walston, J; McBurnie, MA; Newman, A; Tracy, RP; Kop, WJ; Hirsch, CH; Gottdiener, J; Fried, LP; Cardiovascular Health Study (Nov ...
These gait patterns are among the most common gait abnormalities in children with cerebral palsy. However, orthopaedic ... but in middle age cardiovascular issues and neoplastic disorders become more prominent.[104] ... functional gastrointestinal abnormalities contributing to bowel obstruction, vomiting, and constipation may also arise. Adults ... surgery to correct anatomical abnormalities or release tight muscles; braces and other orthotic devices; rolling walkers; and ...
Studies of chronically exposed workers though have thus far failed to detect any abnormalities of thyroid function, including ... Cardiovascular system. *99mTc (Sestamibi. *Tetrofosmin). *111In (Imciromab). *82Rb (Rubidium chloride) ...
It may indicate either degree of abnormality on a continuum or kind of abnormality in a classification. It's influenced by non- ... Cardiovascular. *Precordial examination. *Peripheral vascular examination. *Heart sounds. *Other *Jugular venous pressure ...
Electrolyte abnormalities, poisoning, drowning, accidental hypothermia, hyperthermia, asthma, anaphylaxis, cardiac surgery, ... "2005 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Part 10.6: ...
Finally, chromosome abnormalities are often detected in cancer samples. A large number of different methods have been developed ... Multidisciplinary specialty clinics that include a clinical geneticist or genetic counselor (cancer genetics, cardiovascular ... Examples of chromosome abnormalities include aneuploidy, chromosomal rearrangements, and genomic deletion/duplication disorders ... Molecular tests are also used in the diagnosis of syndromes involving epigenetic abnormalities, such as Angelman syndrome, ...
Cardiovascular system stubs. Hidden categories: *Infobox medical condition. *All articles with dead external links ...
Digital rectal examination (DRE) may allow a doctor to detect prostate abnormalities. Cystoscopy shows the urinary tract from ... As the average life expectancy increases due to advances in the treatment of cardiovascular, pulmonary and other chronic ... where a Gleason score of 10 indicates the most abnormalities. The pathologist assigns a number from 1 to 5 for the most common ...
B23.2) HIV disease resulting in haematological and immunological abnormalities, not elsewhere classified]] ... A52.0) Cardiovascular syphilis. *(A52.1) Symptomatic neurosyphilis *Tabes dorsalis. *(A52.2) Asymptomatic neurosyphilis ...
This may reveal abnormalities of red blood cell shape and form. When red blood cells sometimes occur as a stack, flat side next ... This practice is hard to detect but may endanger the human cardiovascular system which is not equipped to deal with blood of ... In polycythemia vera the increased number of red blood cells results from an abnormality in the bone marrow. ... Yazdanbakhsh K, Lomas-Francis C, Reid ME (October 2000). "Blood groups and diseases associated with inherited abnormalities of ...
"Cardiovascular Drugs and Therapy / Sponsored by the International Society of Cardiovascular Pharmacotherapy. 23 (1): 49-59. doi ... Consequently, a given abnormality in the expression or activity of ALOX5 due to variations in its gene may promote or suppress ... "Cardiovascular Research. 101 (3): 522-32. doi:10.1093/cvr/cvt339. PMC 3928003. PMID 24368834.. ... Consequently, abnormalities in the ALOX5 gene may vary with the population and individuals studied. ...
AF is linked to several forms of cardiovascular disease but may occur in otherwise normal hearts. Cardiovascular factors known ... Dilation of the atria can be due to almost any structural abnormality of the heart that can cause a rise in the pressure within ... "Methodist DeBakey Cardiovascular Journal. 10 (1): 18-24. doi:10.14797/mdcj-10-1-18. PMC 4051329. PMID 24932358.. ... "Methodist DeBakey Cardiovascular Journal. 11 (2): 100-03. doi:10.14797/mdcj-11-2-100. PMC 4547664. PMID 26306127.. ...
Public health initiatives to lower the risk of cardiovascular disease have resulted in lower discretionary salt use at the ... and patients with other risk factors are at a higher risk of experiencing iodine-induced thyroid abnormalities.[24] In ...
Preparticipation screening for cardiovascular abnormalities in young competitive athletes BMJ 2008; 337 :a1596 ... Athletes with abnormalities on initial evaluation are investigated further and those with potentially serious abnormalities are ... Recommendations and considerations related to preparticipation screening for cardiovascular abnormalities in competitive ... of which were eventually diagnosed as a cardiovascular abnormality. The investigators reported an electrocardiographic ...
... with the following concomitant lipid abnormalities: Elevated levels of small, dense low-density lipoprotein (LDL)... more ... Cardiovascular risk in people with diabetes is related in part to insulin resistance, ... Which lipid abnormalities contribute to cardiovascular risk in type 2 diabetes mellitus (DM)?) and Which lipid abnormalities ... Which lipid abnormalities contribute to cardiovascular risk in type 2 diabetes mellitus (DM)?. Updated: Oct 07, 2020 ...
Cardiovascular drugs can cause a variety of acid-base and electrolyte abnormalities that need to be considered when clinicians ... Acid-base and electrolyte abnormalities observed in patients receiving cardiovascular drugs.. Miltiadous G1, Mikhailidis DP, ... Survival advantage with cardiovascular drugs: are they real? [J Cardiovasc Pharmacol Ther. 2003] ... well as on the treatment of these metabolic derangements that are commonly encountered in patients who receive cardiovascular ...
... and other cardiovascular abnormalities. There is currently no targeted therapy, and it is unknown whether cardiovascular ... Cardiovascular abnormalities in CS result from KATP channel GoF in VSM cells. To directly test whether cardiac remodeling ... Glibenclamide reverses cardiovascular abnormalities of Cantu syndrome driven by KATP channel overactivity. Conor McClenaghan,1, ... There are currently no targeted therapies for CS and it is not known if, or to what extent, cardiovascular abnormalities can be ...
Almost a years treatment with a vitamin D compound did not alleviate key structural and functional cardiovascular ... abnormalities in patients with kidney disease and cardiac enlargement. ... Vitamin D Does Not Reduce Cardiovascular Abnormalities in Kidney Disease Patients. by Thilaka Ravi on February 15, 2012 at 11: ... the current study was designed to investigate the impact of paricalcitol treatment on specific cardiovascular abnormalities. ...
... risk independent of the metabolic abnormalities that often accompany it. Therefore, the objective of this study was to evaluate ... It remains unclear whether abdominal obesity increases cardiovascular disease (CVD) ... Cardiovascular disease risk of abdominal obesity vs. metabolic abnormalities Obesity (Silver Spring). 2011 Apr;19(4):853-60. ... The Framingham Offspring, Atherosclerosis Risk in Communities, and Cardiovascular Health studies were pooled to assess the ...
Child obesity often is accompanied by cardiovascular abnormalities, and early detection and prevention programs are needed to ... HealthDay News) - Child obesity often is accompanied by cardiovascular abnormalities, and early detection and prevention ... obese children may show early signs of cardiovascular dysfunction. Some of the abnormalities detected in obese children and ... and colleagues reviewed the literature to summarize current research on cardiovascular abnormalities in children with obesity. ...
Congenital, inherited, or acquired anomalies of the CARDIOVASCULAR SYSTEM, including the HEART and BLOOD VESSELS. ...
Eligibility and Disqualification Recommendations for Competitive Athletes With Cardiovascular Abnormalities: Task Force 14: ... Eligibility and disqualification recommendations for competitive athletes with cardiovascular abnormalities: Task Force 14: ... Eligibility and Disqualification Recommendations for Competitive Athletes With Cardiovascular Abnormalities: Task Force 14: ... Eligibility and Disqualification Recommendations for Competitive Athletes With Cardiovascular Abnormalities: Task Force 14: ...
Electrocardiographic Repolarization Complexity and Abnormality Predict All-Cause and Cardiovascular Mortality in Diabetes. The ... Electrocardiographic Repolarization Complexity and Abnormality Predict All-Cause and Cardiovascular Mortality in Diabetes ... Electrocardiographic Repolarization Complexity and Abnormality Predict All-Cause and Cardiovascular Mortality in Diabetes ... Electrocardiographic Repolarization Complexity and Abnormality Predict All-Cause and Cardiovascular Mortality in Diabetes ...
Potential of Aleglitazar to Reduce Cardiovascular Risk in Patients With Stable Cardiovascular Disease and Glucose Abnormalities ... A PHASE 3B STUDY TO EVALUATE THE POTENTIAL OF ALEGLITAZAR TO REDUCE CARDIOVASCULAR RISK IN PATIENTS WITH STABLE CARDIOVASCULAR ... A Study on The Potential of Aleglitazar to Reduce Cardiovascular Risk in Patients With Stable Cardiovascular Disease and ... potential of aleglitazar to reduce cardiovascular risk in patients with stable cardiovascular disease and glucose abnormalities ...
Potential of Aleglitazar to Reduce Cardiovascular Risk in Patients With Stable Cardiovascular Disease and Glucose Abnormalities ... A PHASE 3B STUDY TO EVALUATE THE POTENTIAL OF ALEGLITAZAR TO REDUCE CARDIOVASCULAR RISK IN PATIENTS WITH STABLE CARDIOVASCULAR ... potential of aleglitazar to reduce cardiovascular risk in patients with stable cardiovascular disease and glucose abnormalities ... Cardiovascular Disease, Diabetes Mellitus Type 2 Drug: Placebo Drug: aleglitazar Phase 3 ...
Methods: Associations of cardiovascular mortality with the isolated minor T-wave abnormalities were studied in citizens who ... Subjects with any major abnormalities on the ECG, history of cardiovascular disease, left bundle branch block, intraventricular ... Conclusions: Isolated minor T-wave abnormalities predicted cardiovascular mortality in subjects with hypertension, whereas they ... Abstract 13339: Isolated Minor Electrocardiographic T-wave Abnormalities and Cardiovascular Mortality in Subjects With and ...
... at Mayo Clinic is investigating the vascular abnormalities in PKD. ... The Cardiovascular Molecular Imaging Lab of Martin G. Rodriguez-Porcel, M.D., ... Polycystic kidney disease (PKD): Vascular abnormalities. The overall aim of the Cardiovascular Molecular Imaging Laboratorys ... to verify the hypothesis that vascular abnormalities are a primary problem in PKD. ...
In the present study, we tested the hypothesis that diabetes-induced activation of PKCβ2 causes cardiovascular abnormalities ... Selective Inhibition of Protein Kinase C β2 Attenuates Inducible Nitric Oxide Synthase-Mediated Cardiovascular Abnormalities in ... Selective Inhibition of Protein Kinase C β2 Attenuates Inducible Nitric Oxide Synthase-Mediated Cardiovascular Abnormalities in ... Selective Inhibition of Protein Kinase C β2 Attenuates Inducible Nitric Oxide Synthase-Mediated Cardiovascular Abnormalities in ...
Cardiovascular Abnormalities Seen in Treatment-Naive RA Patients. Cardiovascular Abnormalities Seen in Treatment-Naive RA ... SLE Patients May Not Receive Enough Cardiovascular Disease Assessment & Treatment. * Patients with Large-Vessel Abnormalities ... SLE Patients May Not Receive Enough Cardiovascular Disease Assessment & Treatment. *Patients with Large-Vessel Abnormalities ... "In early RA patients such as those investigated in our study, the presence of abnormalities and impact of DMARD has not been ...
Number 10-03: Unicuspid aortic valve and associated abnormalities. Case from: Marc Dweck, John Payne, David Northridge, Claire ...
... abnormalities,linked,with,increased,risk,of,cardiovascular,events,in,women,medicine,medical news today,latest medical news, ... abnormalities are independentl...Pablo Denes M.D. of the Feinberg School of Medicine Northwestern Un...The sample analyzed ... Postmenopausal women without symptoms of cardiovascular problems who h...Resting 12-lead electrocardiogram (ECG) ... Postmenopausal women without symptoms of cardiovascular problems who have minor or major abnormalities on an electrocardiogram ...
May the best friend be an enemy if not recognized early: possible role of omega-3 against cardiovascular abnormalities due ... ATYPICAL ANTIPSYCHOTICS DRUGS, AUTISM AND CARDIOVASCULAR ABNORMALITIES. Antipsychotic therapy has become indispensable in the ... Pode um melhor amigo ser um inimigo se não reconhecido a tempo: possível papel do ômega-3 nos efeitos cardiovasculares ... OMEGA-3 AND CARDIOVASCULAR SYSTEM: ANTIARRHYTHMIC PROPERTIES AND PREVENTION OF SUDDEN CARDIAC DEATH ...
... and there were no cardiovascular safety concerns. The cardiovascular abnormalities identified may be related to Pompe disease ... Cardiovascular abnormalities in late-onset Pompe disease and response to enzyme replacement therapy. Forsha, D.; Li, J. S.; ... Baseline cardiovascular abnormalities, and efficacy and safety of enzyme replacement therapy were described. Three pediatric ... PURPOSE: We evaluated the prevalence of cardiovascular abnormalities and the efficacy and safety of enzyme replacement therapy ...
Sitosterolemia: Diagnosis, Metabolic and Hematological Abnormalities, Cardiovascular Disease and Management. Author(s): Jose ... Title:Sitosterolemia: Diagnosis, Metabolic and Hematological Abnormalities, Cardiovascular Disease and Management. VOLUME: 26 ... Metabolic and Hematological Abnormalities, Cardiovascular Disease and Management", Current Medicinal Chemistry (2019) 26: 6766 ... Hematological abnormalities (hemolytic anemia and macrothrombocytopenia) may be present in 25-35% of patients, in whom it is ...
Adults with genetic syndromes and cardiovascular abnormalities: clinical history and management. Genet Med 2008;10:469-94. ... It remains the commonest chromosomal abnormality in live born infants1 and its association with cardiovascular anomalies is ... Cardiovascular abnormalities in Downs syndrome: spectrum, management and survival over 22 years ... Cardiovascular abnormalities in Downs syndrome: spectrum, management and survival over 22 years ...
Objectives: To compare the steady-state lipid and ECG abnormalities in children with SCA to the controls and examine the ... However, the relationship between ECG and lipid abnormalities among children with sickle cell disease is not fully understood. ... However, the mean triglyceride and serum ALT levels in those with ECG abnormalities were significantly higher than those ... Elevated triglyceride and serum ALT levels are possible biochemical markers of ECG abnormalities in these patients. ...
Right Ventricular Abnormalities on Cardiovascular Magnetic Resonance Imaging in Patients With Sarcoidosis ...
JACC: Cardiovascular Imaging. Volume 7, Issue 10, October 2014 DOI: 10.1016/j.jcmg.2014.03.022 PDF Article ... Mechanical Abnormalities Detected With Conventional Echocardiography Are Associated With Response and Midterm Survival in CRT ...
... abnormalities (ECG-CVD) are predictive of subsequent CVD events in the general population. Systemic lupus erythematosus (SLE) ... ST-segment and/or T-wave abnormalities, left ventricular hypertrophy (LVH), left axis deviation (LAD), left bundle branch block ... Electrocardiogram (ECG) cardiovascular disease (CVD) abnormalities (ECG-CVD) are predictive of subsequent CVD events in the ... ECG-CVD electrocardiogram cardiovascular disease abnormalities, LAD left axis deviation, LBBB left bundle branch block, LVH ...
Gotway, M. B., Nagai, B. K., Dawn, S. K., Reddy, G. P., Araoz, P. A., & Webb, W. R. (2001). Cardiovascular abnormalities ... structural abnormalities of the interatrial septum, aortic and pericardial abnormalities, and abnormalities of surgical ... structural abnormalities of the interatrial septum, aortic and pericardial abnormalities, and abnormalities of surgical ... structural abnormalities of the interatrial septum, aortic and pericardial abnormalities, and abnormalities of surgical ...
We conclude that early identification of subclinical cardiovascular abnormalities is important to reduce overt cardiovascular ... Subclinical cardiovascular abnormalities in patients with juvenile systemic lupus erythematosus. *Nur Canpolat, ... The aim of this study is to evaluate subclinical cardiovascular abnormalities including atherosclerosis and left ventricular ... Non-invasive cardiovascular assessments were made on 22 patients with juvenile SLE (20 girls, aged 15.0 ± 2.7 years) with GFR ≥ ...
In three MPS VII dogs that received heterologous BMT at 6 weeks of age, the echocardiographic abnormalities were improved, and ... Echocardiographic abnormalities in dogs with MPS type VII (Sly syndrome, β-glucuronidase deficiency) included mitral valve ... Clinical characterization of cardiovascular abnormalities associated with feline mucopolysaccharidosis I and VI. Meg M. Sleeper ... Effects of bone marrow transplantation on the cardiovascular abnormalities in canine mucopolysaccharidosis VII. @article{ ...
Talk:Cardiovascular System - Abnormalities. From Embryology. Revision as of 08:08, 8 January 2019 by Z8600021. (talk , contribs ... Cite this page: Hill, M.A. (2021, May 16) Embryology Cardiovascular System - Abnormalities. Retrieved from https://embryology. ... Color flow mapping has played a dominant role in the detection of abnormalities during the first trimester, regardless of the ... Pendse N, Gupta S, Geelani MA, Minhas HS, Agarwal S, Tomar A, Banerjee A. Source Department of Cardiovascular & Thoracic ...
  • Researchers have found that almost a year's treatment with a vitamin D compound did not alleviate key structural and functional cardiovascular abnormalities in patients with kidney disease and heart enlargement. (medindia.net)
  • Several studies have suggested that vitamin D therapy may improve cardiovascular health, so we were surprised that the results did not support our hypothesis that paricalcitol, which we use to treat hyperparathyroidsm in kidney disease patients, would reduce left ventricular hypertrophy and improve diastolic function in these patients," says Ravi Thadhani, MD, MPH, of the Massachusetts General Hospital Division of Nephrology, lead author of the JAMA report. (medindia.net)
  • Since kidney disease patients are at increased risk of cardiovascular disease, which may be associated with vitamin D deficiency, the current study was designed to investigate the impact of paricalcitol treatment on specific cardiovascular abnormalities. (medindia.net)
  • It remains unclear whether abdominal obesity increases cardiovascular disease (CVD) risk independent of the metabolic abnormalities that often accompany it. (nih.gov)
  • 4 , 11 - 14 Notably, this scenario is in striking contrast to collapse caused by cardiovascular disease with ventricular tachyarrhythmias, which is typically virtually instantaneous. (ahajournals.org)
  • This randomized, double-blind, placebo-controlled, parallel group, multicenter study will evaluate the potential of aleglitazar to reduce cardiovascular risk in patients with stable cardiovascular disease and glucose abnormalities. (clinicaltrials.gov)
  • Subjects with any major abnormalities on the ECG, history of cardiovascular disease, left bundle branch block, intraventricular conduction delay, or non-sinus rhythm were excluded. (ahajournals.org)
  • The overall aim of the Cardiovascular Molecular Imaging Laboratory's PKD vascular project is to investigate the vascular abnormalities in polycystic kidney disease. (mayo.edu)
  • Patients with RA have abnormalities in left ventricular remodeling, but to date cardiac studies have not been conducted in patients with early, treatment-naive disease. (the-rheumatologist.org)
  • To investigate, Dr. Buch and colleagues performed cardiac magnetic resonance imaging in 66 patients with early RA and no history of cardiovascular disease and 30 healthy controls matched by age, sex, and blood pressure. (the-rheumatologist.org)
  • Longitudinal evaluation with repeat cardiac MRI will allow us to answer whether the abnormalities we have reported improve, whether this depends on reduction in disease activity, and whether it matters how this is achieved, i.e. (the-rheumatologist.org)
  • Patients with established RA who have reduced disease activity also have lower risk of cardiovascular events, she added. (the-rheumatologist.org)
  • Resting 12-lead electrocardiogram (ECG) abnormalities are independently associated with incident coronary heart disease (CHD) and cardiovascular disease (CVD) events. (bio-medicine.org)
  • PURPOSE: We evaluated the prevalence of cardiovascular abnormalities and the efficacy and safety of enzyme replacement therapy in patients with late-onset Pompe disease. (luriechildrens.org)
  • CONCLUSIONS: Although some patients with late-onset Pompe disease had abnormalities on baseline electrocardiogram or echocardiogram, those classically seen in infantile Pompe disease, such as significant ventricular hypertrophy, were not noted. (luriechildrens.org)
  • The cardiovascular abnormalities identified may be related to Pompe disease or other comorbid conditions. (luriechildrens.org)
  • The main clinical features are tendinous and cutaneous xanthomas, arthritis or arthralgia, premature cardiovascular disease and atherosclerosis. (eurekaselect.com)
  • However, the relationship between ECG and lipid abnormalities among children with sickle cell disease is not fully understood. (journals.co.za)
  • Electrocardiogram (ECG) cardiovascular disease (CVD) abnormalities (ECG-CVD) are predictive of subsequent CVD events in the general population. (biomedcentral.com)
  • 8 ] found that resting ECG abnormalities (ECG-CVD 4-elements), in particular ST-segment and/or T-wave abnormalities, left ventricular hypertrophy (LVH), left axis deviation (LAD), left bundle branch block (LBBB) and right bundle branch block (RBBB), were associated with subsequent CVD events (e.g., sudden coronary heart disease death, nonfatal myocardial infarction, and congestive heart failure). (biomedcentral.com)
  • Systemic lupus erythematosus (SLE) have accelerated atherosclerosis and increased risk of cardiovascular disease. (biomedcentral.com)
  • Our result suggested that subclinical cardiovascular disease begins in the early years of life. (biomedcentral.com)
  • We conclude that early identification of subclinical cardiovascular abnormalities is important to reduce overt cardiovascular disease in patients with SLE. (biomedcentral.com)
  • Gene therapy ameliorates cardiovascular disease in dogs with mucopolysaccharidosis VII. (semanticscholar.org)
  • What I know about lt. atrial abnormalities suggest heart disease, hypertension, systemic illness etc. (ourhealth.com)
  • Cardiovascular disease , any of the diseases, whether congenital or acquired, of the heart and blood vessels . (britannica.com)
  • In Asia and the islands of the Pacific, hypertensive cardiovascular disease, disease involving high blood pressure, constitutes a major health hazard. (britannica.com)
  • Congenital heart disease is one of the important types of diseases affecting the cardiovascular system, with an incidence of about 8 per 1,000 live births. (britannica.com)
  • Researchers and health-care providers treating people with HIV are taking these reports seriously, and increasing attention has been devoted to cardiovascular disease at recent medical conferences. (thebody.com)
  • The researchers compared data from 16 HIV positive people with cardiovascular disease and 32 HIV positive people without heart disease. (thebody.com)
  • In thyroid disease, dyslipidemia coexists with various metabolic abnormalities and induce insulin resistance and oxidative stress via a vice-vicious cycle. (hindawi.com)
  • Thyroid disease, namely hypothyroidism and hyperthyroidism, constitutes the most common endocrine abnormality in recent years, diagnosed either in subclinical or clinical form. (hindawi.com)
  • Thyroid disease is associated with various metabolic abnormalities, due to the effects of thyroid hormones on nearly all major metabolic pathways. (hindawi.com)
  • Dyslipidemia is a common metabolic abnormality in patients with thyroid disease, either in the overt or subclinical forms of the disease, and constitutes the end result of the effect of thyroid hormones in all aspects of lipid metabolism leading to various quantitative and/or qualitative changes of triglycerides, phospholipids, cholesterol, and other lipoproteins [ 3 ]. (hindawi.com)
  • In thyroid disease, dyslipidemia and the coexisting metabolic abnormalities, in combination with the thyroid hormone-induced hemodynamic alterations, explain the high risk for cardiovascular disease [ 4 - 7 ]. (hindawi.com)
  • The present work aimed at evaluating EEG abnormalities among children with congenital and rheumatic heart disease. (who.int)
  • The purpose of this article is to review the evidence for the importance of the childhood risk factors for adult cardiovascular disease and to outline the evidence for the efficacy of primary prevention in young people. (bmj.com)
  • Journal of Cardiovascular Disease Research (J Cardiovasc. (jcdronline.org)
  • Lipid abnormalcies, high blood pressure, fleshiness, smoke, and household history of cardiovascular disease have been identified as the chief hazard factors involved in CHD. (hcamatcollegepark.com)
  • You can send a epub magnesium deficiency in the pathogenesis of disease early roots of cardiovascular skeletal and renal website and market your ia. (toruscapital.com)
  • Of epub magnesium deficiency in the pathogenesis of disease early roots of cardiovascular skeletal and, it has a view that always takes double be to Edition, but there have not not of Notes who are to control formatted. (toruscapital.com)
  • clearly the instances read highly successfully submitted Africa to date the many epub magnesium deficiency in the pathogenesis of disease early roots of cardiovascular. (toruscapital.com)
  • HFCS produced dose dependent increases of circulating lipid/lipoprotein risk factors for cardiovascular disease and uric acid within 2 weeks. (greenmedinfo.com)
  • The risk of cardiovascular disease increases with increased weight. (walking-canes.net)
  • All of these diseases states act singularly and synergistically to increase your risk of cardiovascular disease and stroke. (walking-canes.net)
  • Di Tullio, Marco R. / Left ventricular mass-geometry and silent cerebrovascular disease : The Cardiovascular Abnormalities and Brain Lesions (CABL) study . (elsevier.com)
  • Should people at low risk of cardiovascular disease take a statin? (bmj.com)
  • Abramson et al.1 recently asked whether persons at low risk for cardiovascular disease (CVD) should take statins. (bmj.com)
  • In the recent years, psoriasis has been recognised as a systemic disease associated with numerous multiorgan abnormalities and complications. (hindawi.com)
  • Abnormalities seen in BMP and Alk3 are associated with some cardiovascular diseases like Ebstein's anomaly and AV conduction disease. (wikipedia.org)
  • Our mission is to build healthier lives, free of cardiovascular diseases and stroke. (ahajournals.org)
  • Cardiovascular diseases are a major cause of health problems and death in developed countries. (britannica.com)
  • Some forms of cardiovascular diseases are becoming less frequent causes of death, and continued research and preventive measures may provide even greater benefits. (britannica.com)
  • Abdel Latif M. Osman , Electroencephalographic abnormalities in children with cardiovascular diseases, J. Egypt. (who.int)
  • Because of the decline in fatal infectious diseases, in the near future congenital abnormalities will become one of the major causes of infant mortality in Bahrain, as is the case in developed countries. (who.int)
  • FDG-PET provides valuable information on the metabolic activity of the cardiovascular diseases, including ischemia, inflammation, and neoplasm. (elsevier.com)
  • The goal of this manuscript is to provide a comprehensive review on the incremental value of PET and MRI in the evaluation of cardiovascular diseases. (elsevier.com)
  • Consecutive patients undertaking CMR study from January 2012 to June 2017 for various cardiovascular diseases were enrolled. (mdpi.com)
  • In the following list you will find some of the most common rare diseases related to Abnormal facial shape and Abnormality of cardiovascular system morphology that can help you solving undiagnosed cases. (mendelian.co)
  • Cardiovascular diseases constitute the main cause of mortality worldwide, ahead of infectious diseases and cancer. (espci.fr)
  • Thrombotic abnormalities (ie, elevated type-1 plasminogen activator inhibitor [PAI-1], elevated fibrinogen) and hypertension are also involved. (medscape.com)
  • Associations of cardiovascular mortality with the isolated minor T-wave abnormalities were studied in citizens who received ECG in the health examination of Moriguchi city, Osaka, Japan in 1997, stratified by presence or absence of hypertension. (ahajournals.org)
  • The isolated minor T-wave abnormalities were observed in 226 subjects (118 without hypertension, 108 with hypertension) and included 4 of Minnesota Code (MC) 5-2, 45 of MC 5-3, and 177 of MC 5-4. (ahajournals.org)
  • Isolated minor T-wave abnormalities predicted cardiovascular mortality in subjects with hypertension, whereas they didn't in those without hypertension. (ahajournals.org)
  • Pheochromocytoma - a tumor which results in an excessive secretion of norepinephrine and epinephrine which promotes vasoconstriction Hyperaldosteronism (Conn's syndrome) - idiopathic hyperaldosteronism, liddle's syndrome (also called pseudoaldosteronism), glucocorticoid remediable aldosteronism Cushing's syndrome - an excessive secretion of glucocorticoids causes the hypertension Hyperparathyroidism Acromegaly Hyperthyroidism Hypothyroidism A variety of adrenal cortical abnormalities can cause hypertension, In primary aldosteronism there is a clear relationship between the aldosterone-induced sodium retention and the hypertension. (wikipedia.org)
  • NEW YORK (Reuters Health)-A new study has identified myocardial and vascular abnormalities in patients with newly diagnosed, treatment-naive rheumatoid arthritis (RA). (the-rheumatologist.org)
  • Discussion of abnormalities in myocardial force production and cardiac filling is presented in Chapter 11 . (mhmedical.com)
  • Interleukin-2 (IL-2) is a cytokine with proven activity against metastatic renal cell carcinoma (RCC) and malignant melanoma (MM). The intravenous administration of high-dose IL-2 is limited by important cardiovascular side effects such as hypotension, fluid retention, arrhythmias, and myocardial chemia, which often cause dose reduction and/or treatment withdrawal. (elsevier.com)
  • Researchers found that patients with myocardial injury had more electrocardiographic abnormalities, higher inflammatory biomarkers, and an increased prevalence of TTE abnormalities when compared to patients without heart injury. (cardiovascularnews.com)
  • It shows that troponin elevation was 5.2% among patients who did not have heart injury, compared to 18.6% for patients with myocardial injury but without echocardiographic abnormalities, and 31.7% for patients with myocardial injury who also had echocardiographic abnormalities. (cardiovascularnews.com)
  • Cardiovascular Magnetic Resonance (CMR)-based T1 mapping and Heart Deformation Analysis (CMR-HDA) can assess the myocardial tissue characteristic and strain of cardiomyopathy. (springer.com)
  • Analysis of wall motion abnormality using echocardiography is an established method for detecting myocardial ischemia. (ox.ac.uk)
  • It remains the commonest chromosomal abnormality in live born infants 1 and its association with cardiovascular anomalies is well established. (bmj.com)
  • want to understand the link between chromosomal abnormalities in parents and recurrent miscarriages? (lookfordiagnosis.com)
  • 2. 1 out of 150 babies is born with a chromosomal abnormality. (lookfordiagnosis.com)
  • Of the few cases that have a genetic nature, the defect may be the result of a single mutant gene , while in other cases it may be associated with a chromosomal abnormality , the most common of which is Down syndrome , in which about 50 percent of afflicted children have a congenital cardiac abnormality. (britannica.com)
  • Which lipid abnormalities contribute to cardiovascular risk in type 2 diabetes mellitus (DM)? (medscape.com)
  • Lipid and electrocardiographic (ECG) abnormalities have been reported in adults with sickle cell anaemia (SCA) and may reflect underlying structural and/ or functional damage. (journals.co.za)
  • To compare the steady-state lipid and ECG abnormalities in children with SCA to the controls and examine the hypothesis that lipid abnormalities are closely related to electrocardiographic abnormalities, and therefore are a reflection of cardiac damage among these children. (journals.co.za)
  • Lipid and ECG abnormalities are common in children with SCA. (journals.co.za)
  • It was also suggested that continuous separation of psoriatic scales caused the permanent loss of lipids which might affect serum lipid abnormalities [ 11 , 12 ]. (hindawi.com)
  • Abstract: The cardiovascular system is affected by a wide range of pathological processes, including neoplastic, inflammatory, ischemic, and congenital aetiology. (elsevier.com)
  • To our knowledge, this is first case study to report associated cardiac abnormality in such patients. (jcdronline.org)
  • The ESCAPE protocol (Early Screening for Cardiac Abnormality with Pre-participation Echocardiography) attempts to meet this need. (primarycaredigest.org)
  • Whether they can assess cardiac abnormality of hypothyroidism (HT) is unknown. (springer.com)
  • To ascertain non-cardiac abnormality (NCA) incidence in patients undergoing clinical cardiovascular magnetic resonance imaging (CMR) and determine such patients' clinical importance. (mdpi.com)
  • Acid-base and electrolyte abnormalities observed in patients receiving cardiovascular drugs. (nih.gov)
  • Cardiovascular drugs can cause a variety of acid-base and electrolyte abnormalities that need to be considered when clinicians manage the large number of patients who receive these agents. (nih.gov)
  • This review focuses on the pathogenetic mechanisms as well as on the treatment of these metabolic derangements that are commonly encountered in patients who receive cardiovascular drugs. (nih.gov)
  • OBJECTIVE: We studied the 15-year cardiovascular mortality and morbidity of newly diagnosed patients with type 2 diabetes and of nondiabetic control subjects and the predictors of cardiovascular mortality in diabetic patients. (diabetesjournals.org)
  • CONCLUSIONS: This long-term study of a well-characterized group of newly diagnosed patients strengthens the view that the prognosis in middle-aged subjects is markedly impaired and that both hyperglycemia and compositional lipoprotein abnormalities are predictors of cardiovascular mortality in patients with type 2 diabetes. (diabetesjournals.org)
  • The study suggests cardiac abnormalities already exist in newly diagnosed patients with RA," senior author Dr. Maya Buch of the University of Leeds in the UK told Reuters Health by email. (the-rheumatologist.org)
  • Epidemiological studies have shown that DMARD treatment reduces the risk of cardiovascular events in RA patients, while anti-TNF treatment is associated with a greater reduction in cardiovascular event risk, Dr. Buch said. (the-rheumatologist.org)
  • In early RA patients such as those investigated in our study, the presence of abnormalities and impact of DMARD has not been evaluated," she said. (the-rheumatologist.org)
  • In accordance to the above mentioned findings, as omega-3 fatty acids per se have a direct cardiovascular protective role, our paper hypothesized that omega-3 fatty acids supplementation in ASD patients treated with atypical antipsychotic drugs may reduce cardiac arrhythmias and hence sudden cardiac death. (scielo.br)
  • Hematological abnormalities (hemolytic anemia and macrothrombocytopenia) may be present in 25-35% of patients, in whom it is usually associated with the main clinical features, as occurs in the 70% of the cases. (eurekaselect.com)
  • Elevated triglyceride and serum ALT levels are possible biochemical markers of ECG abnormalities in these patients. (journals.co.za)
  • Awareness of the imaging appearance of the various cardiovascular abnormalities that may be incidentally encountered with HCTPA will facilitate accurate diagnosis and may provide additional useful information in patients with negative studies. (elsevier.com)
  • Non-invasive cardiovascular assessments were made on 22 patients with juvenile SLE (20 girls, aged 15.0 ± 2.7 years) with GFR ≥90 ml/min/1.73 m 2 , following in a single center. (biomedcentral.com)
  • Most common abnormality was VCA, seen in 78 (8.5%) patients with large conus or acute marginal or septal branch crossing the RVOT. (biomedcentral.com)
  • Early detection of structural abnormalities may dictate more appropriate treatments, including anticoagulation and other approaches for hospitalized and post-hospitalized patients," said study author Valentin Fuster, director of Mount Sinai Heart and physician-in-chief of The Mount Sinai Hospital, New York, USA. (cardiovascularnews.com)
  • We found that among COVID-19 patients who underwent transthoracic echocardiography, these cardiac structural abnormalities were diverse and present in nearly two-thirds of patients. (cardiovascularnews.com)
  • Abnormalities were diverse, with some patients exhibiting multiple abnormalities. (cardiovascularnews.com)
  • Since there are few LS patients who have undergone a complete cardiovascular evaluation, the nature and clinical prognosis of cardiovascular abnormalities in this syndrome remain uncertain. (bvsalud.org)
  • To determine the sensitivity and specificity of fibrillin protein abnormalities in the diagnosis of MFS, we studied dermal fibroblasts from 57 patients with classical MFS, 15 with equivocal MFS, 8 with single-organ manifestations, and 16 with other connective tissue disorders including homocystinuria and Ehlers-Danlos syndrome. (nih.gov)
  • Significant correlations were found for phenotypic features including arachnodactyly, striae distensae, cardiovascular manifestations, and fibrillin groups II and IV, which included 70% of the MFS patients. (nih.gov)
  • The latter included most of the equivocal MFS/single manifestation patients with fibrillin abnormalities. (nih.gov)
  • Women with cardiovascular conditions should be cared for during pregnancy by a cardio-obstetrics team or health care providers experienced in high-risk pregnancies to provide specialized maternity care for the mother and fetus, according to a new American Heart Association scientific statement, Cardiovascular Considerations in Caring for Pregnant Patients, published today in the Association's flagship journal Circulation. (news-medical.net)
  • To evaluate the various congenital cardiac malformations those are associated with abnormalities of lateralization, and to discuss the diagnostic tools, therapeutic options, and outcome for these patients. (cambridge.org)
  • We studied 134 patients, who had been admitted to our department of paediatric cardiology with known abnormalities of lateralization and congenital cardiac defects between 1990 and 2003. (cambridge.org)
  • 122 Cardiac Abnormalities are Common in Patients Diagnosed with Phaeochromocytoma as Detected by Cardiovascular Magnetic Resonance Imaging. (ox.ac.uk)
  • This is a prospective, multicentre study using cardiovascular magnetic resonance (CMR) imaging to describe the variety and incidence of cardiac abnormalities in patients diagnosed with phaeochromocytoma. (ox.ac.uk)
  • Congenital, inherited, or acquired anomalies of the CARDIOVASCULAR SYSTEM, including the HEART and BLOOD VESSELS. (bioontology.org)
  • Background The prevalence of cardiovascular anomalies in Down's syndrome is well described, but there are few data on spectrum, management and outcome. (bmj.com)
  • Methods The regional paediatric cardiology database in Newcastle upon Tyne provided information on all cardiovascular anomalies, surgical treatment and outcome. (bmj.com)
  • Cardiovascular anomalies are common in Down's syndrome. (bmj.com)
  • Most cardiovascular anomalies in Down's syndrome are amenable to complete surgical correction in infancy. (bmj.com)
  • Surgical management of cardiovascular anomalies has changed considerably over the past two decades, with improving surgical results and reduced mortality especially in the peri-operative period. (bmj.com)
  • In this study we aimed to describe the prevalence and spectrum of cardiovascular anomalies in infants with Down's syndrome in a defined population over a 22-year period, and to assess surgical outcome and survival over time. (bmj.com)
  • Such abnormalities include systemic venous anomalies, atrial and ventricular masses, structural and congenital lesions of the pulmonary arteries, structural abnormalities of the interatrial septum, aortic and pericardial abnormalities, and abnormalities of surgical conduits and bypass grafts. (elsevier.com)
  • A wide range of clinical abnormalities, including cardiac and renal anomalies, may be found (Table 1 ). (aappublications.org)
  • The majority of cardiovascular system anomalies have a multifactorial mode of inheritance [5]. (who.int)
  • Classification and terminology of cardiovascular anomalies. (cambridge.org)
  • Aim: To examine the relation between blood pressure and retinal microvascular abnormalities in older people. (elsevier.com)
  • Signs of focal microvascular abnormalities (focal arteriolar narrowing, arteriovenous nicking, and retinopathy) were evaluated from photographs according to standardised methods. (elsevier.com)
  • Conclusions: Retinal microvascular abnormalities are related to elevated concurrent blood pressure in older people. (elsevier.com)
  • Tielsch, J. M. / Retinal microvascular abnormalities and blood pressure in older people : The Cardiovascular Health Study . (elsevier.com)
  • The aim of this study is to evaluate subclinical cardiovascular abnormalities including atherosclerosis and left ventricular hypertrophy (LVH) in children and adolescent with SLE. (biomedcentral.com)
  • But there is good reason to believe that common-sense risk reduction strategies can help delay or prevent cardiovascular problems such as atherosclerosis, heart attacks, and strokes. (thebody.com)
  • To reduce the future burden of CHD, we need to define prevention and intervention strategies that decrease the prevalence of cardiovascular risk factors in children and young adults and thereby hope to retard atherogenic processes. (bmj.com)
  • The surface electrocardiogram (ECG) remains the most widely used noninvasive method for cardiovascular (CV) risk assessment. (diabetesjournals.org)
  • Postmenopausal women without symptoms of cardiovascular problems who have minor or major abnormalities on an electrocardiogram are at increased risk for future cardiovascular events and death, according to a study in the March 7 issue of JAMA. (bio-medicine.org)
  • The cardiac effects of this syndrome consist of left ventricular hypertrophy (LVH), pulmonary stenosis (PS), coronary artery dilatation and electrocardiogram ( ECG ) abnormalities . (bvsalud.org)
  • Type 2 diabetes is associated with increased risk of cardiovascular (CV) and all-cause mortality. (diabetesjournals.org)
  • Computerized ECG measures of repolarization abnormality and complexity predict CV and all-cause mortality in type 2 diabetes, supporting their use to identify high-risk individuals with diabetes. (diabetesjournals.org)
  • Abnormalities of ventricular repolarization on the ECG, such as ST segment depression (STD) and QT interval prolongation, are well-established markers of mortality risk in the general population ( 1 - 6 ). (diabetesjournals.org)
  • Therefore, the present study examined the value of repolarization abnormalities on the ECG, as characterized by STD and a prolonged rate-corrected QT interval (QTc), and repolarization complexity, as measured by the PCA ratio, for prediction of CV and all-cause mortality in adults with diabetes. (diabetesjournals.org)
  • Hyperglycemia and compositional lipoprotein abnormalities as predictors of cardiovascular mortality in type 2 diabetes: a 15-year follow-up from the time of diagnosis. (diabetesjournals.org)
  • In univariate analyses and various multiple logistic regression analyses, hyperglycemia was a constant predictor of cardiovascular mortality assessed at the time of diagnosis or at 5- or 10-year examinations. (diabetesjournals.org)
  • Cardiovascular complications are recognized to be the major cause of morbidity and mortality associated with diabetes ( 1 ). (diabetesjournals.org)
  • Quite interesting, substantial evidence from epidemiological and case-control studies indicates that omega-3 reduces the risk of cardiovascular mortality, particularly sudden cardiac death. (scielo.br)
  • The study looked at the presence of cardiac troponin elevations in combination with the presence of echocardiographic abnormalities, and found that the combination was associated with worse prognosis and mortality than troponin elevations alone. (cardiovascularnews.com)
  • Although electrocardiographic measures of repolarization abnormality and complexity stratify risk in the general population, their prognostic value in diabetes has not been well characterized. (diabetesjournals.org)
  • Data are sparse regarding the prevalence, incidence, and independent prognostic value of minor and/or major electrocardiographic abnormalities in asymptomatic postmenopausal women. (bio-medicine.org)
  • 0.01).Eight major cardiovascular events causing IL-2 infusion withdrawal were observed (two ischemic electrocardiographic modifications, three grade III-IV hypotension, one atrial fibrillation, one pericardial effusion, one acute heart failure). (elsevier.com)
  • Although abdominal obesity is an important clinical tool for identification of individuals likely to possess metabolic abnormalities, these data suggest that the metabolic syndrome and diabetes are considerably more important prognostic indicators of CVD risk. (nih.gov)
  • Uremia is a clinical syndrome marked by elevated concentrations of urea in the blood and associated with fluid, electrolyte, and hormone imbalances and metabolic abnormalities, which develop in parallel with deterioration of renal function. (medscape.com)
  • Data on live births with Down's syndrome were obtained from the Northern Congenital Abnormality Survey (NorCAS). (bmj.com)
  • 342 (42%) infants with Down's syndrome had a cardiovascular anomaly. (bmj.com)
  • One-year survival in Down's syndrome with a cardiovascular anomaly improved from 82% in 1985-1995 to 94% in 1996-2006. (bmj.com)
  • Echocardiographic abnormalities in dogs with MPS type VII (Sly syndrome, β-glucuronidase deficiency) included mitral valve thickening and insufficiency, large aortic dimensions in both the long and short axes, and thickened aortic valves. (semanticscholar.org)
  • What are the odds to having a down syndrome baby with 2 ultrasound abnormalities? (lookfordiagnosis.com)
  • What are my odds for having a down syndrome baby at 30 with these abnormalities being present? (lookfordiagnosis.com)
  • Therefore, when an X-linked disorder is identified in a female, the possibility of Turner syndrome caused by monosomy X (absence of an X chromosome: 45,X) or a structural abnormality of an X chromosome should be considered. (aappublications.org)
  • For example, folate deficiency, which is associated with fetal CHD and Down syndrome [ 6 ] and is a risk factor for developmental abnormalities, is related to the maternal DNA hypomethylation status. (ijbs.com)
  • This syndrome consists of multiple systemic abnormalities . (bvsalud.org)
  • Other complications, such as components of the metabolic syndrome or cardiovascular dysfunction, have not been extensively studied in children. (clinicaltrials.gov)
  • A study conducted by researchers at Northwestern University, Chicago, has found that the placentas of pregnant women who were infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) showed abnormalities, compared with those of uninfected women. (news-medical.net)
  • Moreover, lipoprotein abnormalities characteristic of type 2 diabetes (low HDL cholesterol, high LDL triglycerides or apolipoprotein B levels, and low LDL cholesterol/apolipoprotein B ratio as a marker for LDL size) were predictive of cardiovascular death in these analyses. (diabetesjournals.org)
  • OBJECTIVE Impaired cardiovascular function in diabetes is partially attributed to pathological overexpression of inducible nitric oxide synthase (iNOS) in cardiovascular tissues. (diabetesjournals.org)
  • Increasing evidence now implicates the abnormal activation of PKCβ 2 , secondary to increased formation of diacylglycerol (DAG) by hyperglycemia, in a number of cardiovascular diabetes complications ( 3 , 5 ). (diabetesjournals.org)
  • ECGs were read by 3 cardiologists with the judgment of minor or major abnormalities blinded to any clinical information including blood pressure except for age and sex. (ahajournals.org)
  • This article provides a factual overview of preparticipation screening, as more general practitioners are likely to be confronted with the questions relating to cardiovascular screening in athletes in countries where systematic screening programmes are currently not available. (bmj.com)
  • The American College of Cardiology (ACC) and American Heart Association (AHA) have recently released a Scientific Statement on "Eligibility and Disqualification Recommendations for Competitive Athletes with Cardiovascular Abnormalities: Preamble, Principles, and General Considerations. (athletesheart.org)
  • Essentially a front-line physician (non-cardiologist) performs an Echo of the heart using a portable ECHO to look for structural abnormalities in their athletes. (primarycaredigest.org)
  • Eligibility and Disqualification Recommendations for Competitive Athletes With Cardiovascular Abnormalities: Task Force 2: Preparticipation Screeni. (cdc.gov)
  • Eligibility and Disqualification Recommendations for Competitive Athletes With Cardiovascular Abnormalities: Preamble, Principles, and General Cons. (cdc.gov)
  • The cyanotic group showed higher incidence of EEG abnormalities [62. (who.int)
  • Isolated minor T-wave abnormalities not accompanied by ST segment abnormalities or findings of left ventricular (LV) hypertrophy are frequently observed in the general population and their prognostic value is less clear as ST segment abnormalities. (ahajournals.org)
  • ECG-CVD were defined as the presence of one or more of the following 4 elements (ECG-4): ST-segment and/or T-wave abnormalities, left ventricular hypertrophy (LVH), left axis deviation (LAD), left bundle branch block (LBBB) and right bundle branch block (RBBB). (biomedcentral.com)
  • The study suggests that 26.3% had right ventricular dysfunction, 23.7% had regional left ventricular wall motion abnormalities, 18.4% had diffuse left ventricular dysfunction, 13.2% had grade II or III diastolic dysfunction, and 7.2% had pericardial effusions. (cardiovascularnews.com)
  • Other conventional atherosclerotic risk factors (eg, family history, smoking, elevated LDL cholesterol) also affect cardiovascular risk. (medscape.com)
  • What is most apparent from the collective findings in this review is that childhood obesity not only increases cardiovascular risk in adulthood, but is also associated with cardiovascular damage during childhood," the authors write. (empr.com)
  • Cardiovascular risk factors were assessed in both groups at baseline and after 5 and 10 years. (diabetesjournals.org)
  • Both minor and major ECG abnormalities linked with increased risk of cardiovascular event. (bio-medicine.org)
  • What are the risk of high abnormalities and pregnancy? (lookfordiagnosis.com)
  • I was wondering what are the risk of having high abnormalities during pregancy. (lookfordiagnosis.com)
  • It remains to be determined whether these cardiovascular manifestations are attributable to HIV infection itself, to antiretroviral drug therapy, to a high prevalence among HIV positive people of traditional risk factors that pose a danger for the population at large -- such as tobacco smoking, older age, male sex, and family history -- or to some other not-yet-known factors. (thebody.com)
  • Unfortunately, this study did not control for additional cardiovascular risk factors. (thebody.com)
  • Background: Neurologic gait abnormalities (NGA) increase risk for falls and dementia, but their pathophysiologic substrates or association with disability have been poorly investigated. (elsevier.com)
  • Moreover, these risk factors usually persist or track into adulthood, so that their effect on the cardiovascular system may be present and influential for several decades. (bmj.com)
  • The cardiovascular health (CVH) metrics are closely related to the risk of stroke. (nature.com)
  • Body fat distribution is a risk factor for several health conditions, although the literature shows that excess body fat is not always associated with cardiometabolic abnormalities in all subjects. (gratisoa.org)
  • OBJECTIVE: Congenital heart defects are the most common major structural fetal abnormalities. (edu.au)
  • HealthDay News) - Child obesity often is accompanied by cardiovascular abnormalities , and early detection and prevention programs are needed to avoid progressive damage at an early age, according to research published online Aug. 14 in the Journal of the American College of Cardiology . (empr.com)
  • Anita T. Cote, PhD, of the University of British Columbia in Vancouver, Canada, and colleagues reviewed the literature to summarize current research on cardiovascular abnormalities in children with obesity. (empr.com)
  • The researchers found that, independent of other obesity-related comorbid conditions, such as dyslipidemia and insulin resistance, obese children may show early signs of cardiovascular dysfunction. (empr.com)
  • Although the pathophysiology and clinical determinants of death in people with SCT participating in intense exercise are not fully understood, cardiovascular collapse likely occurs under conditions that (in laboratory studies) promote HbS polymerization and erythrocyte sickling. (ahajournals.org)
  • There was no statistical difference in the sociodemographic and clinical characteristics of the SCA children with or without ECG abnormalities. (journals.co.za)
  • In particular, characteristic cardiovascular effects in LS may include variable clinical manifestations from benign to life -threatening courses . (bvsalud.org)
  • Potentially significant results have been identified as abnormalities that require further clinical or radiological follow-up or therapy. (mdpi.com)
  • Cardiac arrest may occur from severe underlying electrolyte abnormalities, such as hyperkalemia , metabolic acidosis , or hypocalcemia . (medscape.com)
  • Bao B, Wang Y, Hu H, Yao H, Li Y, Tang S, Zheng L, Xu Y, Liang Z. Karyotypic and Molecular Genetic Changes Associated With Fetal Cardiovascular Abnormalities: Results of a Retrospective 4-Year Ultrasonic Diagnosis Study. (ijbs.com)
  • Impossibility of diagnosis of certain disorders that manifest themselves with the functional development of the infant, e.g. mental retardation, eye and ear abnormalities. (who.int)
  • Magnetic resonance imaging (MRI) and positron emission tomography (PET) are state-of-the-art imaging modalities used in the evaluation of these cardiovascular disorders. (elsevier.com)
  • Methods: The Cardiovascular Health Study is a prospective cohort study conducted in four US communities initiated in 1989 to 1990. (elsevier.com)
  • Improving Visual Detection of Wall Motion Abnormality with Echocardiographic Image Enhancing Methods. (ox.ac.uk)
  • Because HCTPA involves the use of thin collimation and high contrast injection rates and volumetric acquisitions, it is ideally suited for evaluating the thoracic vascular system and may reveal numerous cardiovascular abnormalities unrelated to venous thromboembolism. (elsevier.com)
  • Cite this page: Hill, M.A. (2021, May 16) Embryology Cardiovascular System - Abnormalities . (edu.au)
  • How is hematology related to the cardiovascular system? (lookfordiagnosis.com)
  • To some degree, as medical science advances, more people are saved from other illnesses only to die from one of the unsolved and uncontrolled disorders of the cardiovascular system . (britannica.com)
  • Any abnormality of the cardiovascular system. (familydiagnosis.com)
  • Danzi S, Klein I (2012) Thyroid hormone and the cardiovascular system. (springer.com)
  • These key skills are fundamental for examination of the cardiovascular system and all medical students and specialist nurses are expected to be proficient at ECG interpretation. (wiley.com)
  • Cardiovascular Physiology, 7e Mohrman DE, Heller LJ. (mhmedical.com)
  • Author Dr. Engelking covers all the section of physiology relevant for veterinary students including sections on body fluids and compartments, neuromuscular physiology and special senses, respiration, cardiovascular physiology, kidneys. (routledge.com)
  • While both perform thoracic (chest cavity) surgeries a cardiovascular surgeon has specialized training and knowledge of heart and blood vessel procedures and disorders. (lookfordiagnosis.com)
  • MRI and FDG-PET can provide complementary information on the evaluation of several cardiovascular disorders. (elsevier.com)
  • Verified segmental deletion or duplications were not directly associated with cardiovascular malformations except in DAAM1 and GATA6. (ijbs.com)
  • In addition, these two groups were associated with shortened "event-free" survival and more severe cardiovascular complications than groups I and III. (nih.gov)
  • Color flow mapping has played a dominant role in the detection of abnormalities during the first trimester, regardless of the International Society of Ultrasound in Obstetrics and Gynecology warning on the use of Doppler during early pregnancy. (edu.au)
  • Cardiovascular magnetic resonance (CMR) with late gadolinium enhancement (LGE) for fibrosis detection and adenosine stress perfusion are key techniques for HCM phenotyping. (biomedcentral.com)
  • The CNP Assurances Foundation is giving its support to the École Supérieure of Industrial Physics and Chemistry of the City of Paris (ESPCI ParisTech) in its ambitious research project directed by Mickael Tanter (photo), intended to improve the detection and management of heart contraction abnormalities. (espci.fr)
  • Totally 5,440 participants were randomly enrolled in the Asymptomatic Polyvascular Abnormalities Community study from 2010 to 2011. (nature.com)
  • This relative thinness and complex geometry make abnormalities of the right ventricle less common than pathological conditions involving the left ventricle, and this further contributes to a lack of understanding of the normal and diseased state of the right ventricle. (bsl.nl)