Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
Controlled physical activity which is performed in order to allow assessment of physiological functions, particularly cardiovascular and pulmonary, but also aerobic capacity. Maximal (most intense) exercise is usually required but submaximal exercise is also used.
A regimen or plan of physical activities designed and prescribed for specific therapeutic goals. Its purpose is to restore normal musculoskeletal function or to reduce pain caused by diseases or injuries.
Abnormal accumulation of serous fluid in two or more fetal compartments, such as SKIN; PLEURA; PERICARDIUM; PLACENTA; PERITONEUM; AMNIOTIC FLUID. General fetal EDEMA may be of non-immunologic origin, or of immunologic origin as in the case of ERYTHROBLASTOSIS FETALIS.
Heart enlargement and other remodeling in cardiac morphology and electrical circutry found in individuals who participate in intense repeated exercises.
Physical activity which is usually regular and done with the intention of improving or maintaining PHYSICAL FITNESS or HEALTH. Contrast with PHYSICAL EXERTION which is concerned largely with the physiologic and metabolic response to energy expenditure.
The exercise capacity of an individual as measured by endurance (maximal exercise duration and/or maximal attained work load) during an EXERCISE TEST.
An island in the Greater Antilles in the West Indies. Its capital is Kingston. It was discovered in 1494 by Columbus and was a Spanish colony 1509-1655 until captured by the English. Its flourishing slave trade was abolished in the 19th century. It was a British colony 1655-1958 and a territory of the West Indies Federation 1958-62. It achieved full independence in 1962. The name is from the Arawak Xaymaca, rich in springs or land of springs. (From Webster's New Geographical Dictionary, 1988, p564 & Room, Brewer's Dictionary of Names, 1992, p267)
X-ray visualization of the chest and organs of the thoracic cavity. It is not restricted to visualization of the lungs.
Expenditure of energy during PHYSICAL ACTIVITY. Intensity of exertion may be measured by rate of OXYGEN CONSUMPTION; HEAT produced, or HEART RATE. Perceived exertion, a psychological measure of exertion, is included.
A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).
An abnormal direct communication between an artery and a vein without passing through the CAPILLARIES. An A-V fistula usually leads to the formation of a dilated sac-like connection, arteriovenous aneurysm. The locations and size of the shunts determine the degree of effects on the cardiovascular functions such as BLOOD PRESSURE and HEART RATE.
Fluid accumulation within the PERICARDIUM. Serous effusions are associated with pericardial diseases. Hemopericardium is associated with trauma. Lipid-containing effusion (chylopericardium) results from leakage of THORACIC DUCT. Severe cases can lead to CARDIAC TAMPONADE.
A disease of the CARDIAC MUSCLE developed subsequent to the initial protozoan infection by TRYPANOSOMA CRUZI. After infection, less than 10% develop acute illness such as MYOCARDITIS (mostly in children). The disease then enters a latent phase without clinical symptoms until about 20 years later. Myocardial symptoms of advanced CHAGAS DISEASE include conduction defects (HEART BLOCK) and CARDIOMEGALY.
Pathophysiological conditions of the FETUS in the UTERUS. Some fetal diseases may be treated with FETAL THERAPIES.
A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
The visualization of tissues during pregnancy through recording of the echoes of ultrasonic waves directed into the body. The procedure may be applied with reference to the mother or the fetus and with reference to organs or the detection of maternal or fetal disease.
Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.
Tumors in any part of the heart. They include primary cardiac tumors and metastatic tumors to the heart. Their interference with normal cardiac functions can cause a wide variety of symptoms including HEART FAILURE; CARDIAC ARRHYTHMIAS; or EMBOLISM.
The rate at which oxygen is used by a tissue; microliters of oxygen STPD used per milligram of tissue per hour; the rate at which oxygen enters the blood from alveolar gas, equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body. (Stedman, 25th ed, p346)
Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.
The time span between the beginning of physical activity by an individual and the termination because of exhaustion.
Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.
The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.
A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
The number of times the HEART VENTRICLES contract per unit of time, usually per minute.
The use of a bicycle for transportation or recreation. It does not include the use of a bicycle in studying the body's response to physical exertion (BICYCLE ERGOMETRY TEST see EXERCISE TEST).
Freedom from activity.
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
The ability to carry out daily tasks and perform physical activities in a highly functional state, often as a result of physical conditioning.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
A type of strength-building exercise program that requires the body muscle to exert a force against some form of resistance, such as weight, stretch bands, water, or immovable objects. Resistance exercise is a combination of static and dynamic contractions involving shortening and lengthening of skeletal muscles.
An activity in which the body is propelled by moving the legs rapidly. Running is performed at a moderate to rapid pace and should be differentiated from JOGGING, which is performed at a much slower pace.
An infant during the first month after birth.
The oxygen consumption level above which aerobic energy production is supplemented by anaerobic mechanisms during exercise, resulting in a sustained increase in lactate concentration and metabolic acidosis. The anaerobic threshold is affected by factors that modify oxygen delivery to the tissues; it is low in patients with heart disease. Methods of measurement include direct measure of lactate concentration, direct measurement of bicarbonate concentration, and gas exchange measurements.
Exercises that stretch the muscle fibers with the aim to increase muscle-tendon FLEXIBILITY, improve RANGE OF MOTION or musculoskeletal function, and prevent injuries. There are various types of stretching techniques including active, passive (relaxed), static, dynamic (gentle), ballistic (forced), isometric, and others.
The exchange of OXYGEN and CARBON DIOXIDE between alveolar air and pulmonary capillary blood that occurs across the BLOOD-AIR BARRIER.
A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
Therapeutic exercises aimed to deepen inspiration or expiration or even to alter the rate and rhythm of respiration.
Elements of limited time intervals, contributing to particular results or situations.
PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.
Instructional programs in the care and development of the body, often in schools. The concept does not include prescribed exercises, which is EXERCISE THERAPY.
The inferior part of the lower extremity between the KNEE and the ANKLE.
Asthma attacks following a period of exercise. Usually the induced attack is short-lived and regresses spontaneously. The magnitude of postexertional airway obstruction is strongly influenced by the environment in which exercise is performed (i.e. inhalation of cold air during physical exertion markedly augments the severity of the airway obstruction; conversely, warm humid air blunts or abolishes it).
Methods or programs of physical activities which can be used to promote, maintain, or restore the physical and physiological well-being of an individual.
The flow of BLOOD through or around an organ or region of the body.
A sport in which weights are lifted competitively or as an exercise.
A state arrived at through prolonged and strong contraction of a muscle. Studies in athletes during prolonged submaximal exercise have shown that muscle fatigue increases in almost direct proportion to the rate of muscle glycogen depletion. Muscle fatigue in short-term maximal exercise is associated with oxygen lack and an increased level of blood and muscle lactic acid, and an accompanying increase in hydrogen-ion concentration in the exercised muscle.
The non-genetic biological changes of an organism in response to challenges in its ENVIRONMENT.
The amount of force generated by MUSCLE CONTRACTION. Muscle strength can be measured during isometric, isotonic, or isokinetic contraction, either manually or using a device such as a MUSCLE STRENGTH DYNAMOMETER.
The chemical reactions involved in the production and utilization of various forms of energy in cells.
The volume of BLOOD passing through the HEART per unit of time. It is usually expressed as liters (volume) per minute so as not to be confused with STROKE VOLUME (volume per beat).
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
An activity in which the body advances at a slow to moderate pace by moving the feet in a coordinated fashion. This includes recreational walking, walking for fitness, and competitive race-walking.
Activities or games, usually involving physical effort or skill. Reasons for engagement in sports include pleasure, competition, and/or financial reward.
The act of breathing with the LUNGS, consisting of INHALATION, or the taking into the lungs of the ambient air, and of EXHALATION, or the expelling of the modified air which contains more CARBON DIOXIDE than the air taken in (Blakiston's Gould Medical Dictionary, 4th ed.). This does not include tissue respiration (= OXYGEN CONSUMPTION) or cell respiration (= CELL RESPIRATION).
Any method of measuring the amount of work done by an organism, usually during PHYSICAL EXERTION. Ergometry also includes measures of power. Some instruments used in these determinations include the hand crank and the bicycle ergometer.
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
Processes and properties of the CARDIOVASCULAR SYSTEM as a whole or of any of its parts.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
Glucose in blood.
The quadriceps femoris. A collective name of the four-headed skeletal muscle of the thigh, comprised of the rectus femoris, vastus intermedius, vastus lateralis, and vastus medialis.
The physical activity of a human or an animal as a behavioral phenomenon.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Difficult or labored breathing.
Salts or esters of LACTIC ACID containing the general formula CH3CHOHCOOR.
The amount of BLOOD pumped out of the HEART per beat, not to be confused with cardiac output (volume/time). It is calculated as the difference between the end-diastolic volume and the end-systolic volume.
Measurement of the various processes involved in the act of respiration: inspiration, expiration, oxygen and carbon dioxide exchange, lung volume and compliance, etc.
Studies comparing two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. In the case of two treatments, A and B, half the subjects are randomly allocated to receive these in the order A, B and half to receive them in the order B, A. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. (Last, A Dictionary of Epidemiology, 2d ed)
An activity in which the body is propelled through water by specific movement of the arms and/or the legs. Swimming as propulsion through water by the movement of limbs, tail, or fins of animals is often studied as a form of PHYSICAL EXERTION or endurance.
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
The process of exocrine secretion of the SWEAT GLANDS, including the aqueous sweat from the ECCRINE GLANDS and the complex viscous fluids of the APOCRINE GLANDS.
A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
The hollow, muscular organ that maintains the circulation of the blood.
Part of the arm in humans and primates extending from the ELBOW to the WRIST.
A method in which either the observer(s) or the subject(s) is kept ignorant of the group to which the subjects are assigned.
An endogenous substance found mainly in skeletal muscle of vertebrates. It has been tried in the treatment of cardiac disorders and has been added to cardioplegic solutions. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1996)
The physical or mechanical action of the LUNGS; DIAPHRAGM; RIBS; and CHEST WALL during respiration. It includes airflow, lung volume, neural and reflex controls, mechanoreceptors, breathing patterns, etc.
Muscular contractions characterized by increase in tension without change in length.
The relative amounts of various components in the body, such as percentage of body fat.
Force exerted when gripping or grasping.
The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.
Enzyme that catalyzes the first step of the tricarboxylic acid cycle (CITRIC ACID CYCLE). It catalyzes the reaction of oxaloacetate and acetyl CoA to form citrate and coenzyme A. This enzyme was formerly listed as EC 4.1.3.7.
The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
Individuals who have developed skills, physical stamina and strength or participants in SPORTS or other physical activities.
A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral and social environment; the overall condition of a human life.
FATTY ACIDS found in the plasma that are complexed with SERUM ALBUMIN for transport. These fatty acids are not in glycerol ester form.
Volume of PLASMA in the circulation. It is usually measured by INDICATOR DILUTION TECHNIQUES.
Therapeutic modalities frequently used in PHYSICAL THERAPY SPECIALTY by PHYSICAL THERAPISTS or physiotherapists to promote, maintain, or restore the physical and physiological well-being of an individual.
Carbohydrates present in food comprising digestible sugars and starches and indigestible cellulose and other dietary fibers. The former are the major source of energy. The sugars are in beet and cane sugar, fruits, honey, sweet corn, corn syrup, milk and milk products, etc.; the starches are in cereal grains, legumes (FABACEAE), tubers, etc. (From Claudio & Lagua, Nutrition and Diet Therapy Dictionary, 3d ed, p32, p277)
The active sympathomimetic hormone from the ADRENAL MEDULLA. It stimulates both the alpha- and beta- adrenergic systems, causes systemic VASOCONSTRICTION and gastrointestinal relaxation, stimulates the HEART, and dilates BRONCHI and cerebral vessels. It is used in ASTHMA and CARDIAC FAILURE and to delay absorption of local ANESTHETICS.
A status with BODY WEIGHT that is grossly above the acceptable or desirable weight, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.
A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
The processes of heating and cooling that an organism uses to control its temperature.
The measure of the level of heat of a human or animal.
Carrying out of specific physical routines or procedures by one who is trained or skilled in physical activity. Performance is influenced by a combination of physiological, psychological, and socio-cultural factors.
Measure of the maximum amount of air that can be expelled in a given number of seconds during a FORCED VITAL CAPACITY determination . It is usually given as FEV followed by a subscript indicating the number of seconds over which the measurement is made, although it is sometimes given as a percentage of forced vital capacity.
Decrease in existing BODY WEIGHT.
The force that opposes the flow of BLOOD through a vascular bed. It is equal to the difference in BLOOD PRESSURE across the vascular bed divided by the CARDIAC OUTPUT.
A disease of chronic diffuse irreversible airflow obstruction. Subcategories of COPD include CHRONIC BRONCHITIS and PULMONARY EMPHYSEMA.
A partial or complete return to the normal or proper physiologic activity of an organ or part following disease or trauma.
The hemodynamic and electrophysiological action of the left HEART VENTRICLE. Its measurement is an important aspect of the clinical evaluation of patients with heart disease to determine the effects of the disease on cardiac performance.
Voluntary cooperation of the patient in following a prescribed regimen.
The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION.
The presence of an increased amount of blood in a body part or an organ leading to congestion or engorgement of blood vessels. Hyperemia can be due to increase of blood flow into the area (active or arterial), or due to obstruction of outflow of blood from the area (passive or venous).
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
The portion of the leg in humans and other animals found between the HIP and KNEE.
A symptom complex characterized by pain and weakness in SKELETAL MUSCLE group associated with exercise, such as leg pain and weakness brought on by walking. Such muscle limpness disappears after a brief rest and is often relates to arterial STENOSIS; muscle ISCHEMIA; and accumulation of LACTATE.
Usual level of physical activity that is less than 30 minutes of moderate-intensity activity on most days of the week.
A vertical distance measured from a known level on the surface of a planet or other celestial body.
A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.
One of the MARTIAL ARTS and also a form of meditative exercise using methodically slow circular stretching movements and positions of body balance.
Confinement of an individual to bed for therapeutic or experimental reasons.
The protein constituents of muscle, the major ones being ACTINS and MYOSINS. More than a dozen accessory proteins exist including TROPONIN; TROPOMYOSIN; and DYSTROPHIN.
The thoracolumbar division of the autonomic nervous system. Sympathetic preganglionic fibers originate in neurons of the intermediolateral column of the spinal cord and project to the paravertebral and prevertebral ganglia, which in turn project to target organs. The sympathetic nervous system mediates the body's response to stressful situations, i.e., the fight or flight reactions. It often acts reciprocally to the parasympathetic system.
Measurement of oxygen and carbon dioxide in the blood.
A pulmonary ventilation rate faster than is metabolically necessary for the exchange of gases. It is the result of an increased frequency of breathing, an increased tidal volume, or a combination of both. It causes an excess intake of oxygen and the blowing off of carbon dioxide.
The superior part of the upper extremity between the SHOULDER and the ELBOW.
These include the muscles of the DIAPHRAGM and the INTERCOSTAL MUSCLES.

The incognita of the known: the athlete's heart syndrome. (1/17)

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The prevalence, distribution, and clinical outcomes of electrocardiographic repolarization patterns in male athletes of African/Afro-Caribbean origin. (2/17)

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Eccentric and concentric cardiac hypertrophy induced by exercise training: microRNAs and molecular determinants. (3/17)

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Chronic Akt blockade aggravates pathological hypertrophy and inhibits physiological hypertrophy. (4/17)

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Gene deletion of P2Y4 receptor lowers exercise capacity and reduces myocardial hypertrophy with swimming exercise. (5/17)

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Pathological role of serum- and glucocorticoid-regulated kinase 1 in adverse ventricular remodeling. (6/17)

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The endurance athletes heart: acute stress and chronic adaptation. (7/17)

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Atrial fibrillation and atrial flutter in athletes. (8/17)

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TY - JOUR. T1 - Do big athletes have big hearts? Impact of extreme anthropometry upon cardiac hypertrophy in professional male athletes. AU - Riding, Nathan R.. AU - Salah, Othman. AU - Sharma, Sanjay. AU - Carré, François. AU - OHanlon, Rory. AU - George, Keith P.. AU - Hamilton, Bruce. AU - Chalabi, Hakim. AU - Whyte, Gregory P.. AU - Wilson, Mathew G.. PY - 2012/11. Y1 - 2012/11. N2 - Aim Differentiating physiological cardiac hypertrophy from pathology is challenging when the athlete presents with extreme anthropometry. While upper normal limits exist for maximal left ventricular (LV) wall thickness (14 mm) and LV internal diameter in diastole (LVIDd, 65 mm), it is unknown if these limits are applicable to athletes with a body surface area (BSA) ,2.3 m 2. Purpose To investigate cardiac structure in professional male athletes with a BSA,2.3 m 2, and to assess the validity of established upper normal limits for physiological cardiac hypertrophy. Methods 836 asymptomatic athletes without a ...
Limited microRNAs (miRNAs, miRs) have been reported to be necessary for exercise-induced cardiac growth and essential for protection against pathological cardiac remodeling. Here we determined members of the miR-17-92 cluster and their passenger miRNAs expressions in two distinct murine exercise models and found that miR-17-3p was increased in both. miR-17-3p ... read more promoted cardiomyocyte hypertrophy, proliferation, and survival. TIMP-3 was identified as a direct target gene of miR-17-3p whereas PTEN was indirectly inhibited by miR-17-3p. Inhibition of miR-17-3p in vivo attenuated exercise-induced cardiac growth including cardiomyocyte hypertrophy and expression of markers of myocyte proliferation. Importantly, mice injected with miR-17-3p agomir were protected from adverse remodeling after cardiac ischemia/reperfusion injury. Collectively, these data suggest that miR-17-3p contributes to exercise-induced cardiac growth and protects against adverse ventricular remodeling. miR-17-3p may ...
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Exercise-induced cardiac growth factors govern c-kitpos endogenous cardiac stem-progenitor cell growth and differentiation in vitro. (A-F) Histogram plots and
Patients with chronic kidney disease have profound exercise intolerance which contributes to an increased risk of cardiovascular disease. The investigators have found that chronic kidney disease patients have an exaggerated increase in blood pressure during certain forms of exercise that could certainly contribute to exercise dysfunction as well as cardiovascular risk. The investigators will test the mechanisms underlying this exaggerated blood pressure response, as well as the potential benefits of short-term tetrahydrobiopterin (BH4) with folic acid on both exercise dysfunction and cardiovascular risk factors in chronic kidney disease. The investigators will test whether short-term treatment with tetrahydrobiopterin (BH4), a cofactor for nitric oxide, together with folic acid improves inflammation, vascular health, and adrenaline levels, both at rest and during exercise in chronic kidney disease ...
(HealthDay)-Sleep-disordered breathing (SDB) severity is associated with lower functional aerobic capacity (FAC) and increased blood pressure, according to a study published in the June 1 issue of The American Journal of ...
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The objective of this work is to study in cardiac MRI the difference between the physiological hypertrophy of the myocardium of the athletes heart and the hypertrophy of the pathological myocardium by comparing athletes (athlete group) to a group of subjects. non-athlete followed for HCM (HCM group).Material and methodsWe conducted a prospective comparative study including 61 subjects. The group of athletes comprised 31 subjects. TheHCM group consisted of 30 subjects. All subjects were paired to age and body surface and had cardiac MRI with the late enhancement study.ResultsThe thickness of the LV wall (mea ...
Learn about the causes, symptoms, diagnosis & treatment of Sports and the Heart from the Professional Version of the Merck Manuals.
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TY - JOUR. T1 - Reduced ischemia and reperfusion injury following exercise training. AU - Libonati, Joseph R.. AU - Gaughan, John P.. AU - Hefner, Colleen A.. AU - Gow, Andrew. AU - Paolone, Albert M.. AU - Houser, Steven R.. PY - 1997. Y1 - 1997. N2 - We examined the effects of two exercise training modalities, i.e., low intensity endurance and sprint running, on in vitro, isovolumic myocardial performance following ischemia and reperfusion. Rats ran on a treadmill 5 d · wk-1 for 6 wk at the following levels: endurance; 20 m · min-1, 0% grade, 60 min · d-1 and sprint; five 1-min runs at 75 m · min-1, 15% grade interspersed with 1-min active recovery runs at 20 m · min-1, 15% grade. Both endurance and sprint training significantly improved exercise tolerance relative to control (P ,0.05) on two graded exercise tests. Buffer perfused hearts of control (N = 18), endurance (N = 20), and sprint (N = 13) trained animals underwent no-flow ischemia (20 min) and reperfusion (30 min) in a ...
What is driving the exaggerated blood pressure response to exercise in patients with peripheral arterial disease (PAD)? In this podcast, Editor in Chief Irving H. Zucker (University of Nebraska Medical Center) interviews senior author Gail Thomas (Penn State College of Medicine) and content expert Hanjun Wang (University of Nebraska Medical Center) about the unique study by Kuczmarski et al. Thomas and co-authors used telemetry to record blood pressure during exercise in conscious animals, both before and after bi-lateral femoral artery ligation. The studied was conducted over a period of two months, a technical success given that the authors used chronically-instrumented conscious animals. Thomas and collaborators found that the blood pressure response was exaggerated as early as 3 days after femoral artery ligation and lasted for the duration of the experiment in both female and male mice. Are the mechanisms that play a role in blood pressure response to short-term ligation, such as cytokines ...
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To the Editor: The role of adults as reservoirs of pertussis was previously well established (1-7). Young army recruits undergoing basic training in the Israeli Defense Force constitute a unique adult population because of their special living and service conditions. This and the fact that they are not vaccinated with the diphtheria, tetanus, and pertussis (DTP) vaccine after the age of 1 year (unlike children in most of the Western countries) led us to hypothesize that this semiclosed population may have an exceptionally high risk for pertussis. These young soldiers are on leave on weekends, during which time they come in close contact with susceptible family members, including young infants, and may thus facilitate the import and export of pertussis between the military setting and the general population. An outbreak of pertussis that recently occurred among infantry soldiers (8) indicated the need to conduct the present study, in which we sought to evaluate the prevalence and incidence of ...
writes: Who knows for sure - it seems most elite marathon runners tend to be on the short side. Luke Puskedra is the newest member of a select group. However, this is inevitable since it appears the suggested values were based on real-life heights and weights of professional runners. After delivering PPE at the height of the pandemic, the pre-med student is running the virtual New York City Marathon to raise funds for health care workers in need. The theory is that, because foot size doesnt necessarily increase in proportion to height, taller runners are subject to greater biomechanical forces, and could have an increased susceptibility to injury. We may earn commission if you buy from a link. This content is created and maintained by a third party, and imported onto this page to help users provide their email addresses. Related, the similarly built shorter runner has a relatively greater surface area, which, everything else being equal, allows for better heat dissipation. Thereafter, he is ...
The world s oldest marathon runner has revealed that he will be retiring at the age of 101 years after one final run in Hong Kong next month.
Like all good stories the story of Dion Leonard, a marathon runner from Scotland, and a stray dog now named Gobi has many twists and turns along the way.
The average athletes heart rate during a marathon is 160 beats per minute. Thats based on a person in his or her 20s who has a resting heart rate of 55 bpm and a maximum heart rate of 200 bpm. A ...
Our Heart & Vascular Center offers dedicated heart rhythm suites and the most advanced technology to detect and treat irregular heart patterns.
Another addition to the clear stamp series called Background Blocks. They are what they say, simply a block of yummy pattern!. Background Blocks Scattered Hearts. This is a lovely scattered outline heart design, which can be stamped once to create a backdrop for a focal point. It has also been designed to be able to stamp to fill a large area to create a random scattered heart pattern.. This stamp measures approximately 6.5 x 9 cm.. PLEASE NOTE:- To protect my designs and discourage the blatant theft of them, there is a watermark over the top of the product image. This makes the image appear that the lines are not solid. I apologise for the inconvenience and ensure you that this is not part of the design or physical stamps you will receive. To see what the stamp/s look like when stamped, please have a look at the samples in the product gallery. Thank you for your understanding. ...
From diet to weekly exercise regimes and everything in between, Harlequins coach Adam Bishop gives loaded the lowdown on what is expected at the elite level
I have been running for years and started running marathons in the past 3 years. My 16-year-old son finished the Napa Valley Marathon with me. He started running 8 months ago as a way to lose weight. I have consistently asked him if he wanted to go running, but he was never interested before. My wife and I thought the marathon training was a one off; hed do it and thatd it. He finished in 3:15 and now he wants to runs 2-4 marathons a year. Hes running track in high school for the first time right now (1600 and 3200 meters).
Im not sure yet. I will be running a marathon the weekend before, so it depends on how my legs feel. I intend to run full out at this marathon. I have a few friends that will be running the SFM so Im thinking of doing the second half (because the first half is just TOO EARLY!) as a fun run and enjoying yet another race experience. Plus it was my very first 1/2 marathon I did...would be nice to start a tradition!. ...
In 2007 I ran the marathon to celebrate my 30th birthday and raise money for St. Elizabeths Hospice, Ipswich, who cared for my Dad in his last few days. Needless to say I am not a natural runner and the experience is one I will never forget.. Prepare yourself for blood, sweat and tears... Wednesday 27th December 2006 20 Minutes approx. 3.21km (On Treadmill). First day of training today. This time yesterday I was eating my second Christmas dinner! Anyway, was able to complete 20 minutes on the treadmill at 10km/hr comfortably so a good start. However, it will be much harder out on the roads so I can look forward to that!. Thursday 28th December 2006 30 Minutes approx. 2.3km. First run outside and started off quite well although I think I started off too fast. Wanted to die after the first very slight hill! I ran round the Orwell Country Park, which was a bit too muddy and slippery. I couldnt complete the 30 minutes; I had to walk one bit of my route (which was uphill and muddy) but then ...
Kenyan distance runners won both the mens and womens divisions of Sundays New York City Marathon. A Harvard evolutionary biologist suggests some possible reasons why.
Now I find myself slowing down, but going much longer distances. I guess Im really becoming an ultramarathoner. Its funny how after two marathons, I still didnt see myself as a marathoner or even a real runner. Since then, I have run about 7 ultras and now across the state of Iowa and Im now thinking I might be an ultramarathoner. Its funny how my past can play such a big part of my view of my world and my future ...
As Mo Farahs collapse at the New York half marathon shows how tough long distance running can be, meet Tony The Fridge Morrison, who runs with a 42kg refrigerator strapped to his back
A month after giving birth to our first child, my wife, Macy, had a crazy idea. She wanted to set a personal best in the marathon. And she wanted to do it soon.
Running long-distance races isn't going to hurt your heart any more than other vigorous sports, researchers say. Just make sure you're fit enough
MATTHEWS, N.C. -- A North Carolina mom is thriving once again after losing three limbs to the flu just two years ago. In 2013, Kristan Seaford caught a bad case of the flu that turned into sepsis and nearly killed her, according to WCNC.
Technology Networks is an internationally recognised publisher that provides access to the latest scientific news, products, research, videos and posters.
Technology Networks is an internationally recognised publisher that provides access to the latest scientific news, products, research, videos and posters.
FORT BENNING, Ga. (AP) - The young Army infantry recruits lined up in full combat gear, guns at the ready. At the signal, a soldier in front kicked in the door and they burst into the room, swiveling to check around the walls for threats. Youre dead! one would-be enemy yelled out from a dark corner, the voice slightly higher than the others echoing through the building. It was 18-year-old Kirsten, training to become one of the Armys first women serving as infantry soldiers.
FORT BENNING, Ga. (AP) - The young Army infantry recruits lined up in full combat gear, guns at the ready. At the signal, a soldier in front kicked in the door and they burst into
WASHINGTON, Sept. 17.―Falling from a height of 75 feet, Orville Wright and Lieut. Thomas E. Selfridge of the Signal Corps were buried in the wreckage of Wrights aeroplane shortly after 5 oclock this afternoon. The young army officer died at 8:10 oclock to-night. Wright is badly hurt, although he probably will recover. The flying machine is a mass of tangled wires, torn and twisted planes, and tattered canvas. The accident was due to the breaking of one of the blades of the propeller on the left side.. Although there had been but a handful of people at the aeronautical testing grounds at Fort Myer during the last few days, fully 2,000 had gathered by 4:30 this afternoon. The aeroplane was still in its shed, but Mr. Wright arrived a few minutes later and ordered it taken to the northern end of the field, to be placed on the starting track in readiness for a flight.. Selfridge In First.. Everybody was ordered back from the machine, and Mr. Wright turned to Lieut. Selfridge and said: You might ...
See this site. Do not be tempted. It used to be called hillbilly heroin, before it became the drug of choice for older professional males.
I was always better at sprinting than running long distance--back in the days when I actually ran...in high shcool. My wife, by way of contrast, was and is a marathon runner. One of the things that Ive noticed as I have watched her run over the years is that she knows how to pace herself.
Another way to estimate is to look at the typical slowdown from 10K pace to marathon pace, which for world-class marathon runners is usually around 24 seconds per mile (6 seconds per 400m) to 28 seconds per mile (7 seconds per 400m). Bekele just ran a marathon at just under 70.0 seconds per 400m, which would work out to a 10K between 26:15 (63 sec pace) and 26:40 (64 sec pace)….while Mo Farah has a 10K PR of 26:46 ...
The best compression arm sleeves to promote blood flow and circulation for running, crossfit training, ultra runners, marathon runners, and triathletes. Also great for obstacle race running and trail running.
Type and Description of Treatments: I recieved 6 rounds of CHOP+E chemotherapy from June 2016 to December 2016. At the end of Januar... How do you feel today? Same as everyday. Very difficult to get going after waking up in the morning. It always feels like it takes until 5 in the afternoon before I feel fully awake. I try to exercise but the toll the stem cell transplant and other treatments have taken on me is profound. I used to be a marathon runner but the effort of running even 1 mile... Continue Reading ...
So why do I feel the need to write this all out? Because it drives me mad that people, who have no idea what its like to have cancer, feel like they can call people, who are fighting for their lives, liars because we dont look sick enough. Why do I have to look sick for you to believe me? First, what does sick look like? And why is it that me looking sick would make you feel more comfortable? Does it make you uncomfortable because if a normal looking girl can get cancer, that means that you could too? You could. Anyone can get cancer. It does not care how old, young, strong, healthy, you are. You could be a vegan marathon runner and somehow still end up with cancer. Anyone could have or get cancer ...
Just in case your feet were feeling the need to get moving (maybe this 91-year-old marathon runner was some inspiration?), today just happens to be National...
For those who trot along the track as speed demons whiz by, rejoice! You dont have to be a sprinter or marathon runner to add years to your life--jogging at a slow or average pace for a couple hours...
Background: Hypertensive patients with large blood pressure (BP) variability have greater risks of cardiovascular events and exaggerated end-organ damages. Recently, we have shown that acute pressure overload triggers transient perivascular inflammation.. Hypothesis: We assessed the hypothesis that large BP variability exaggerates hypertensive cardiac remodeling through the activation of myocardial inflammation.. Methods and Results: A new rat model of chronic hypertension with exaggerated BP variability was created by performing bilateral sino-aortic denervation (SAD) in spontaneous hypertensive rats (SHRs). Seven weeks after SAD (n=10) or sham (n=7) operation (week 7), 24-hour BP was monitored telemetrically in SAD+SHRs and sham+SHRs. Although mean BP was similar in the two groups, SAD+SHRs had greater BP variability (larger standard deviation and covariance of mean BP), compared with sham+SHRs. Both the two groups showed concentric left ventricular (LV) hypertrophy, and SAD aggravated LV ...
Purpose:Partial body cryotherapy (PBC) has been shown to be beneficial for post-exercise recovery, however, no study has demonstrated the effectiveness of PBC as a recovery modality following elite rugby union (RU) training. RU is a unique sport that involves high velocity collisions with minimal protective wear and may represent a situation that could induce greater performance decrements than other sports, thus PBC could be beneficial. The application of PBC in real-world, as opposed to the laboratory setting, has rarely been investigated during the competitive phase of a playing season and warranted investigation.Methods:In a counterbalanced sequential research design, professional rugby athletes (n = 18, age, 25.4 ± 4.0 years; training age, 7.2 ± 4.0 years; mass, 99.8 ± 10.6 kg and height 188.3 ± 6.0 cm) were assigned to a 12-week PBC intervention, washout period (4 weeks) and reassessed as their own controls. Total self-reported well-being, muscle soreness, sleep quality and ...
Totally, 142 HF patients with midrange ejection fraction (HFmrEF) and reduced ejection fraction (HFrEF) were enrolled in the study. There was a significantly correlation both between the EF and the EPSS and between the EF and the LVIDd/EPSS (P,0.001). In both HFmrEF and HFrEF groups, the correlation between the LVIDd/EPSS and the EF was more significant than was the correlation between the EPSS and the EF (P,0.001). The results of the linear regression analysis indicated that the LVIDd/EPSS was an independent predictor of the HFmrEF and the HFrEF (P,0.001). In the patients with EPSS≤12, there was a significant association between the EF and the LVIDd/EPSS (P,0.001) but not between the EF and the EPSS(P,0.05). The receiver operating characteristic curve analysis showed that the LVIDd/EPSS predicted advanced HF with 87% sensitivity and 72% specificity, using a cutoff value of 3.35,and it predicted the HFrEF (EF,40%) with 84% sensitivity and 81% specificity, using a cutoff value of 3.75.. ...
Were the only UK clinic offering Tecar Therapy to Marathon Runners, Triathletes, Cyclists, Iron Men and Martial Artists - record recovery speeds are possible using specialist technology and years of experience in diagnosis and treatments.
Thank you for your interest in spreading the word on Circulation.. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address. ...
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2002-10-07. The runner who collapsed last Sunday during the real,- BERLIN-MARATHON could not have been saved by the rescue workers, who were there immediately. This is the conclusion made by the doctor in charge during the race, Dr. Willi Heepe, after having received background medical information about the deceased man. The 50-year-old man from Hamburg was a top manager who despite his stress at work put himself under pressure in his free time, as well. The runner, who was not married and did not have any children, also suffered high blood pressure. The race on Sunday was the mans 4th marathon this year. Just three weeks earlier, he had pushed himself to the limit in a marathon in Münster. He had announced to his doctor before the real,- BERLIN-MARATHON that he definitely wanted to make it under three hours. As he reached the last few kilometres on the Kurfürstendamm and he was getting close to his time limit, he tried to extract the last power out of his body and then collapsed. Since he ...
Two miles earlier I would have scoffed at the preposterous thought of running 2 miles at that pace. Things had changed, however, and all of a sudden I felt really calm and relaxed, and I just knew I would do it. I knew it would hurt, I knew it would be by far the best finish I had ever produced in a marathon, but I was in The Zone, and I wasnt going to snap out of it. I still kept passing runner after runner, and I knew that I would be able to push on until the end. The last mile finally spots a decent number of spectators, and they finally made some noise, which was good. It was just after the 25 mile marker, with a mile to go, that I got hit by the first cramp. In my last marathon, in Loch Ness, a similar thing had happened over the last two miles, and I had slowed down a lot. This time it was different, however; the cramps were not caused by mere fatigue but by the fact that I was basically running faster than my body was able to do for a sustained period of time. However, the cramps never ...
cardiomegaly - MedHelps cardiomegaly Center for Information, Symptoms, Resources, Treatments and Tools for cardiomegaly. Find cardiomegaly information, treatments for cardiomegaly and cardiomegaly symptoms.
The focus of our laboratory is heart function and exercise. Key questions we are trying to answer include: • what are the cardiac consequences of excessive exercise performed over a lifetime • what are the mechanisms of exercise-induced cardiac fatigue • how does the heart adapt to acute and chronic exercise in health and disease We have an interest in the spectrum of health, from long-standing athletes to clinical populations including heart failure, hypertension and atrial fibrillation.
The runner who collapsed during the Colorado Marathon on Sunday remains hospitalized at Medical Center of the Rockies in Loveland.
Greg McQuaid has been running a marathon every weekend for the past 33 weeks. On Sunday, hell attempt to keep his streak going in Santa Rosa.
We are grateful to each and every one of you for the hours of training youve put in and the fundraising activities youve organised - not to mention the impressive sponsorship youve secured. We hope you are now feeling excited about the big day - we will be there cheering you on and we hope the knowledge that you are helping so many people affected by the most common blood cancer spurs you on if things get tough. We really couldnt do what we do without you! Our 2019 #TeamLymphoma runners are:
Sigma-Aldrich offers abstracts and full-text articles by [Viola Grabs, Tobias Peres, Otto Zelger, Bernhard Haller, Axel Pressler, Siegmund Braun, Martin Halle, Johannes Scherr].
Results Application of the 2010 ESC criteria, compared with the 2005 criteria, reduced the number of participants with abnormal ECG findings from 83/508 (16.3%) to 49/508 (9.6%). The reduction in the number of abnormal ECGs was driven by the reclassification of participants with isolated QRS voltage criteria for left ventricular hypertrophy from abnormal to normal. Of the 49 participants with abnormal ECGs, 14/49 (29%) had a single ECG abnormality and 35/49 (71%) had two or more abnormalities. The use of the 2010 criteria was associated with improved specificity (reduction in the false positive rate) and preserved sensitivity when compared with the 2005 criteria. ...
Legendary two-time Olympic marathon runner Liz Yelling is a definitive source on marathon training. Heres her advice for a successful run.
Choline supplementation may provide benefits for stamina athletes such as for example marathon runners, in addition to more casual sports athletes, by avoiding
Three years ago, I signed up for the Dublin City Marathon. We did a fundraiser for Special Olympics Ireland and had about 35 people running, virtually all of us first-time marathon runners. I broke the four hours so I was pleased about that.. ...
www.ncbi.nlm.nih.gov/pubmed/22002517 Probably nothing terribly new here. You cannot be a powerlifter and a marathon runner, or at least not good at both. Found this interesting t, team42470board
Recalling my most fit season of life, I realized I had been neglecting fitness care. As a pedestrian, I havent necessarily needed to do much intentional cardio to stay shapely, but I remembered how much I loved running before I had Aviel. As I researched adrenal fatigue, which is how I have been self-treating prior to discovery that my Cushings is adenoma related, I learned that running actually puts stress on the body and causes a release of cortisol. Its not necessarily recommended for those struggling with adrenal problems, but I departed from the suggestion and went for it. My logic is that the good endorphins are worth the small amount of stress. Im not a marathon runner... just 20 minutes at a time. And I think this was a good choice. I feel so much better when Im running regularly. It builds my confidence to meet my goals, and it increases my energy through out the day. I really do have this sense that I am more than a conqueror. For that, it is totally worth it ...
About Cardiomegaly - Welcome to my allnursesPage! You can learn all about me here. Together, we can learn, share, and network with nurses and nursing students from all around the world.
... induced by exercise could be suggestive of cardiomyopathy, ischemia or channelopathies. The most important initial ... Evidence of cardiomegaly and peripheral edema may indicate heart failure and ischemia or a valvular abnormality. Blood tests, ... Supraventricular tachycardias can also be induced at the termination of exercise when the withdrawal of catecholamines is ... Vagus nerve induced palpitation is felt as a thud, a hollow fluttery sensation, or a skipped beat, depending on at what point ...
It is not uncommon to undergo cardiopulmonary exercise testing (CPET), which measures the heart's response to exercise, to ... it is believed that the eccentric hypertrophy is induced by volume-overload and that the concentric hypertrophy is induced by ... Athletic heart syndrome Cardiac fibrosis Cardiology Cardiomegaly Cardiovascular disease Right ventricular hypertrophy ECG See ... It is a response to 'volume-overload', either as a result of increased blood return to the heart during exercise, or a response ...
A patient with a frame shift mutation of c.227delC displayed symptoms of neutropenia, cardiomegaly, and other common symptoms ... Based on studies of cervical cancer progression, it is believed that TAZ may induce cancer by inhibiting apoptosis and ... November 2011). "Impaired cardiac reserve and severely diminished skeletal muscle O₂ utilization mediate exercise intolerance ... Another c.C153G mutation resulted in severe metabolic acidosis, cardiomegaly, and other major symptoms of Barth syndrome. There ...
Tentative evidence suggests that home-based exercise programs may be more efficient at improving exercise adherence. While a ... Cardiovascular late side-effects have been termed radiation-induced heart disease (RIHD) and radiation-induced vascular disease ... Inflammatory cardiomegaly Myocarditis - inflammation of the myocardium, the muscular part of the heart, caused most often by ... Insufficient physical activity (defined as less than 5 x 30 minutes of moderate activity per week, or less than 3 x 20 minutes ...
The boy was put into a medically induced coma and taken to a hospital; there, he underwent head surgery, in which a portion of ... On January 5, 1996, two trainers were injured by cougars during an exercise session. One trainer was in the cougar enclosure to ... the coroner's report later stated that she died due to cardiomegaly, and had been seeing a cardiologist for treatment. On ...
People with Lyme arthritis should limit their level of physical activity to avoid damaging affected joints, and in case of ... The spirochetes may also induce host cells to secrete quinolinic acid, which stimulates the NMDA receptor on nerve cells, which ... In 10-15% of people, Lyme causes myocardial complications such as cardiomegaly, left ventricular dysfunction, or congestive ... Schneider BS, Schriefer ME, Dietrich G, Dolan MC, Morshed MG, Zeidner NS (October 2008). "Borrelia bissettii isolates induce ...
Shortness of breath, chest pain, decreased ability to exercise, irregular heartbeat[1]. ... decreased ability to exercise, and an irregular heartbeat.[1] The duration of problems can vary from hours to months.[1] ... A period of no exercise is typically recommended during recovery.[1][2] Corticosteroids or intravenous immunoglobulin (IVIG) ...
Long-term endurance exercise that far exceeds the recommended amount of exercise (e.g., long-distance cycling or marathon ... Finally, nicotine induces the formation of patterns of collagen type III in the atrium and has profibrotic effects. All this ... Exercise stress testing[edit]. Some individuals with atrial fibrillation do well with normal activity but develop shortness of ... Regular aerobic exercise improves atrial fibrillation symptoms and AF-related quality of life.[15] The effect of high-intensity ...
This is the basis for the so-called fight-or-flight response, but such stimulation can also be induced by stimulants such as ... from healthy response to exercise or from cardiac arrhythmia), and that tachyarrhythmia be reserved for the pathologic form ( ... such as with exercise) or abnormal (such as with electrical problems within the heart). ...
Medications and exercise are roughly equally effective.[64] High levels of physical activity reduce the risk of coronary artery ... Chronic high-grade narrowing of the coronary arteries can induce transient ischemia which leads to the induction of a ... Exercise; aerobic exercise, like walking, jogging, or swimming, can reduce the risk of mortality from coronary artery disease.[ ... Exercise and physical activity in the prevention and treatment of atherosclerotic cardiovascular disease. Major Recommendations ...
The chronic nandrolone treatment impairs the exercise-induced cardioprotection against ischaemia/reperfusion injury by ... Nandrolone impaired the exercise-induced cardioprotection, but this effect was prevented by losartan (AT1-R antagonist) and ... AT1 and aldosterone receptors blockade prevents the chronic effect of nandrolone on the exercise-induced cardioprotection in ... Conclusion: The chronic nandrolone treatment impairs the exercise-induced cardioprotection against ischaemia/reperfusion injury ...
Use of Exercise Stress Tests (EST) to Screen for CAD. To reduce the risk of heart attacks and sudden cardiac arrest among FFs, ... Cardiomegaly (an enlarged heart) weighing 560 grams (normal is less than 400 grams)1 ... but his untimely death is much more likely due to an MI-induced heart arrhythmia. ... Consider conducting exercise stress tests for male FFs above the age of 45 years with two or more risk factors for CAD. ...
By contrast, the exercise induced dyspnoea and orthopnoea progressed to the point where his capacity to perform activities of ... GE: Chest radiograph was normal with no cardiomegaly and normal lung fields. Spirometry was normal (forced expiratory volume in ... His chest X-ray now showed cardiomegaly, blunted costophrenic angles and bilateral lower zone infiltrates. A further ... peripheral oedema and a reduction in exercise tolerance to approximately 10 m walking. Upper gastrointestinal endoscopy was ...
5) Exercise-induced ischemia or ventricular arrhythmias observed by radionuclide stress test during an evaluation reaching at ... Cardiomegaly (enlarged heart; heart weighed 660 grams [g]; predicted normal weight is 463 g [ranges between 351 g and 611 g as ... Health and Wellness Programs. The FD does not have a wellness/fitness program, and no exercise equipment is available in the ... 4) Maximal exercise tolerance of , 42 milliliters of oxygen per minute per kilogram or , 12 metabolic equivalents (METs) ...
Here we report a case of a 20-year-old woman with a history of exercise intolerance since childhood that was misinterpreted as ... with chronic dyspnea on exertion and exercise intolerance that was attributed to and treated as presumed exercise-induced ... Chest X-ray showed no cardiomegaly (Supplemental Figure 2). Serial cardiac enzymes were negative. In the light of cardiac ... as exercise-induced asthma. The key for an early diagnosis before the occurrence of permanent cardiac damage is a careful ...
... decreased exercise capacity and shortness of breath during exercise ■ ECG: low voltage of QRS complexes and P and T waves ■ CXR ... Clinical Manifestations of Hypothyroidism -- Cardiovascular System ■ Myxedema induces coronary artery disease ?? ■ CAD more ... cardiomegaly  interstitial edema, myofibrillary swelling, LV dilatation, pericardial effusion * 11. ... and decreased exercise capacity  impaired respiratory function + cardiovascular disease ■ Hypoventilation (shallow and slow ...
However, his exercise tolerance was well. Any dyspnea on effort had not seen during out-patient clinic (NYHA I). Ventilation/ ... A chest radiograph revealed marked cardiomegaly and mediastinum expansion without a difference of increased radiolucency ... Hemodynamic collapse induced by general anesthesia in a patient with an unruptured thoracic aortic aneurysm: a case report. ... Two cases of TAA-induced severe hypoxia with compression of the left main bronchus and right pulmonary artery have been ...
We are hoping its athletes heart [athletic bradycardia, or exercise-induced cardiomegaly] and VTAC, after years of pushing so ...
Cardiomegaly, Exercise-Induced, Cardiomyopathies, Coronary Vessels, Death, Sudden, Cardiac, Echocardiography, ... Clinical Topics: Arrhythmias and Clinical EP, Heart Failure and Cardiomyopathies, Noninvasive Imaging, Sports and Exercise ... Consensus Statement of the Study Group of Sport Cardiology of the Working Group of Cardiac Rehabilitation and Exercise ... Ethnic differences in physiological cardiac adaptation to intense physical exercise in highly trained female athletes. ...
Exercise capacity, lung congestion, maximal oxygen consumption, arterial oxygen saturation, and survivorship were all improved ... Results: At 100 days post-TAC, untreated KATP channel-deficient hearts developed cardiomegaly, regional and global left ... Abstract 12573: Induced Pluripotent Stem Cells Treatment Prevent Heart Failure and Ventricular Dyssynchrony in Genetic Non- ... Abstract 12573: Induced Pluripotent Stem Cells Treatment Prevent Heart Failure and Ventricular Dyssynchrony in Genetic Non- ...
... thereby inducing hypothermia, thus benefiting patients suffering from illnesses characterized by tissue anoxia. ... Cardiomegaly is a medical condition wherein the heart is enlarged. It can often be associated with other serious medical ... lack of exercise and increasing average lifespan. The main causes of death and disability among cardiovascular diseases are ... WO2009071097A1 - Use of hypothermia inducing drugs - Google Patents. Use of hypothermia inducing drugs Download PDF Info. ...
Also known as athletic bradycardia, or exercise-induced cardiomegaly, Athletes heart is generally considered benign, but may ... Activity data from wearables may help us identify individuals more likely to have this condition due to exercise, and are ... "An enlarged left ventricle could be caused by heart disease or harmless adaptation to sustained exercise, and these two ...
Moreover, the exercise induced diastolic dysfunction may persist despite cessation of exercise. Kono et al reported that the ... 1963) Value of prolonged bed rest in management of cardiomegaly. JAMA 183:81-87. ... 1993) Effect of heart failure on the mechanism of exercise-induced augmentation of mitral valve flow. Circ Res 72:795-806. ... Conclusions Exercise induced diastolic left ventricular dysfunction of the failing heart persists for 24 hours or more after ...
keywords = "blood pressure, cardiomegaly, exercise-induced, exercise, hypertension, hypertrophy, left ventricular",. author = " ...
1 Cardiomegaly, Exercise-Induced. *1 Congenital heart defects. *1 Congenital heart disease ... No Synergic Effect of Sildenafil Administration on Exercise Capacity Improvement in a Fontan Patient with Regular Exercise ... Kindergarten Children with Congenital Heart Disease Show Good Physical Activity but Reduced Motor Skills in Comparison with ...
We found that alterations in the signaling pathways tested here had no impact on exercise performance. Exercise induced cardiac ... We found that alterations in the signaling pathways tested here had no impact on exercise performance. Exercise induced cardiac ... We found that alterations in the signaling pathways tested here had no impact on exercise performance. Exercise induced cardiac ... We found that alterations in the signaling pathways tested here had no impact on exercise performance. Exercise induced cardiac ...
Cardiomegaly, Exercise-Induced / physiology Actions. * Search in PubMed * Search in MeSH * Add to Search ... The athletes ECG and the exercise related sudden cardiac death]. Trachsel LD, Wilhelm M. Trachsel LD, et al. Ther Umsch. 2015 ...
Exercise-Induced/genetics , Cardiomegaly/genetics , Exercise/physiology , MicroRNAs/physiology , Cardiomegaly, Exercise-Induced ... Animals , Male , Rats , Cardiomegaly, Exercise-Induced/drug effects , Cardiomegaly, Exercise-Induced/physiology , Heart/drug ... Humans , Atrial Fibrillation/etiology , Cardiomegaly, Exercise-Induced , Atrial Fibrillation/diagnosis , Cardiomegaly, Exercise ... There is no fibrosis and no cardiac dysfunction in eccentric or concentric hypertrophy induced by exercise training. Therefore ...
Cardiomegaly (Heart Hypertrophy) 10/15/1987 - "Lactate dehydrogenase activity increased significantly (P less than 0.01) in ... These data indicate that (1) beta-adrenergic blockade prevents training-induced cardiac hypertrophy; (2) beta-antagonists have ... myocardium may increase its ability to utilize lactate during exercise with training despite beta 1-blockade.". ...
Androgen and glucocorticoid mechanisms in exercise-induced cardiac hypertrophy. Download Prime PubMed App to iPhone, iPad, or ... AndrogensAnimalsCardiomegalyFemaleGlucocorticoidsHeart VentriclesOrgan SizePhysical ExertionRatsRats, Inbred StrainsReceptors, ... Androgen cytosol binding in exercise-induced sparing of muscle atrophy.. *Glucocorticoid-induced cardiac hypertrophy: additive ... Androgen and glucocorticoid mechanisms in exercise-induced cardiac hypertrophy.. Am J Physiol. 1984 Jun; 246(6 Pt 2):H761-7.AJ ...
Animals , Male , Rats , Cardiomegaly, Exercise-Induced/drug effects , Cardiomegaly, Exercise-Induced/physiology , Heart/drug ... Objective: Assess hypertrophic response of the association of thyroid hormone and exercise in the rat heart. Methods: We used ... Conclusion: The association of thyroid hormone with high-intensity exercise produced cardiac hypertrophy, and generated a ... thyroid hormone and exercise (H + E); the group received daily hormone levothyroxine sodium by gavage at a dose of 20 μg ...
Increased sympathetic discharge may induce sinus tachycardia. Is there a cardiac history? ... Cardiomegaly. Congestive heart failure or cardiomyopathy. Holter monitor or event recorder. Capture aberrant rhythm, frequency ... Graded exercise test. Preexcitation or aberrant rhythm. Type of tachyarrhythmia. Echocardiography. Structural or valvular ...
Time course alterations of myocardial endothelin-1 production during the formation of exercise training-induced cardiac ... Time course alteration of endothelin-1 gene expression in the heart during exercise and recovery from post-exercise periods in ... Time dilation induced by object motion is based on spatiotopic but not retinotopic positions. Au, R. K. C., Ono, F. & Watanabe ... Time-dependent resonant UHF CI approach for the photo-induced dynamics of the multi-electron system confined in 2D QD. Okunishi ...
Sex differences in morphological and functional aspects of exercise-induced cardiac hypertrophy in a rat model. Oláh, A., ... Characterization of the dynamic changes in left ventricular morphology and function induced by exercise training and detraining ... Relationship between Cardiac Remodeling and Exercise Capacity in Elite Athletes: Incremental Value of Left Atrial Morphology ... sensitivity correlates with left ventricular contractility during the progression of pressure overload-induced left ventricular ...
Cardiomegaly, Exercise-Induced. *Hemodynamics. *Myocardial Contraction. *Neovascularization, Physiologic. *Ventricular Function ... Right ventriculo-arterial uncoupling and impaired contractile reserve in obese patients with unexplained exercise intolerance. ...
Cardiomegaly, Exercise-Induced. *Hemodynamics. *Myocardial Contraction. *Neovascularization, Physiologic. *Ventricular Function ... Association between lung ultrasound findings and invasive exercise haemodynamics in patients with undifferentiated dyspnoea. ...
... in marathoners with exercise induced hypertension compared to normotensive controls before and after running a marathon. ". 02/ ... Cardiomegaly (Heart Hypertrophy) 04/01/1996 - "These data suggest that blocking the action of endothelin-1 with a receptor ... 06/01/2013 - "Based on these studies, drugs that increase NO bioavailability, attenuate endothelin-1 induced pulmonary ... 01/2010 - "The purpose of this study was to determine the role of endothelin 1 in mediating sFlt-1-induced hypertension in ...
... exercise capacity, blood pressure response, and ventilation efficiency. They are also useful to assess exercise-induced ... Those with minimal TR and mild cardiomegaly usually do not need surgery and lead normal lives. Patients with ASD or PFO are at ... Low-to-medium intensity physical activity is encouraged. Physical activity in patients with a history of arrhythmias should be ... or aortic root dilation should avoid isometric exercise and should limit exercise to low-intensity activities or sports. The ...
Extreme cardiomegaly induced by rheumatic heart disease Published November 07, 2018. * Minerva Swollen hands and feet syndrome ...
  • Exercise studies were performed on females from six different genetic mouse models that have been shown to exhibit alterations in pathological cardiac adaptation and hypertrophy. (elsevier.com)
  • Impact statement: This research is relevant as the hypertrophic signaling pathways tested here have only been characterized for their role in pathological hypertrophy, and not in the context of exercise or physiological hypertrophy. (elsevier.com)
  • Conclusion: The association of thyroid hormone with high-intensity exercise produced cardiac hypertrophy, and generated a standard hypertrophy not directly correlated to the degree of fibrosis. (bvsalud.org)
  • Among the molecular, biochemical and cellular processes that orchestrate the development of the different phenotypes of cardiac hypertrophy in response to physiological stimuli or pathological insults, the specific contribution of exercise training has recently become appreciated. (bvsalud.org)
  • Physiological cardiac hypertrophy involves complex cardiac remodeling that occurs as an adaptive response to static or dynamic chronic exercise, but the stimuli and molecular mechanisms underlying transduction of the hemodynamic overload into myocardial growth are poorly understood. (bvsalud.org)
  • This review summarizes the physiological stimuli that induce concentric and eccentric physiological hypertrophy, and discusses the molecular mechanisms, sarcomeric organization, and signaling pathway involved, also showing that the cardiac markers of pathological hypertrophy (atrial natriuretic factor, β-myosin heavy chain and α-skeletal actin) are not increased. (bvsalud.org)
  • There is no fibrosis and no cardiac dysfunction in eccentric or concentric hypertrophy induced by exercise training. (bvsalud.org)
  • Here, we show that the angiotensin II type 1 (AT1) receptor is locally activated in pathological and physiological cardiac hypertrophy, although with exercise training it can be stimulated independently of the involvement of angiotensin II. (bvsalud.org)
  • These findings show that glucocorticoids, rather than androgens, undergo adaptive changes in the circulation and in muscle during the development of exercise-induced cardiac hypertrophy. (unboundmedicine.com)
  • When stressors that encourage this concentric hypertrophy are reduced or eliminated (either surgically corrected in the case of cardiac defects, or hypertension is reduced from diet and exercise) it is possible for the heart to undergo 'reverse remodeling', returning to a somewhat more 'normal' state instead of progressing to a dilated, pathologic phenotype. (wikipedia.org)
  • This resulted in extreme cardiomyocyte proliferation and hypertrophy - excessive growth of the individual cardiomyocytes - leading to a giant heart (cardiomegaly) that left little room for blood to enter. (labroots.com)
  • We propose that growth-factor-induced skeletal-muscle hypertrophy and changes in myofibre phenotype are mediated by calcium mobilization and are critically regulated by the calcineurin/NF-ATc1 signalling pathway. (nih.gov)
  • Various aetiologies, in reaction to this, may induce compensatory mechanisms consisting of excentric (dilatation) and concentric hypertrophy. (ox.ac.uk)
  • Design and patients Transmitral flow velocity profiles and standard non-invasive haemodynamic indices were obtained serially over seven days after symptom limited bicycle exercise tests in 18 patients with dilated cardiomyopathy and eight normal subjects. (bmj.com)
  • Results The intensity of exercise, as assessed by respiratory gas analysis, was lower in patients with dilated cardiomyopathy than in normal subjects. (bmj.com)
  • In contrast, patients with dilated cardiomyopathy showed a sustained decrease in the peak early diastolic filling velocity and a sustained increase in the deceleration time of early filling for 24 hours or more after exercise. (bmj.com)
  • Because other haemodynamic variables recovered within one hour after exercise even in patients with dilated cardiomyopathy, the postexercise changes in ventricular filling were not explained by changes in loading conditions. (bmj.com)
  • The efficacy of exercise training on a daily basis in dilated cardiomyopathy requires further evaluation. (bmj.com)
  • In this study, we investigated the recovery process of the exercise induced diastolic left ventricular dysfunction in patients with dilated cardiomyopathy, using reproducible Doppler echocardiographic techniques. (bmj.com)
  • Chest radiographs revealed mild cardiomegaly with a normal pulmonary vascular pattern. (ispub.com)
  • A chest X-ray showed mild cardiomegaly ( Fig.1a ). (accjournal.org)
  • These oral medications have been shown to improve exercise intolerance, pulmonary arterial pressure, and even pulmonary vascular resistance in people. (vin.com)
  • In these patients, bosentan was effective and was found to decrease vascular remodeling in induced pulmonary hypertension, improve myocardial function, and decrease ventricular remodeling. (vin.com)
  • A, treatment is shorter act- ing exercise-induced and renin influ- ences vascular smooth muscle. (st-systemtronic.com)
  • It is virtually totally excreted balance of vascular spasm of warfarin metabolism and cardiomegaly. (st-systemtronic.com)
  • Trauma-associated dissections most frequently diagnosed viriga pills in a patient present with cardiomegaly, vascular congestion, or tenderness. (dvas.org)
  • LV systolic, diastolic, and vascular function will be examined at rest and during graded supine exercise at fixed and varied preload to definitively characterize both baseline differences and discrepancies in cardiovascular reserve function that only become apparent during stress, when HFpEF patients typically become symptomatic11. (strokecenter.org)
  • However, although acute cardiovascular changes induced during BHD and fatal complicaitons by extreme diving have been studied, the long-term effects of shallow but frequent intermittent apnea by repetitive BHD have not been well studied. (biomedcentral.com)
  • The Holiday heart syndrome, also referred to as alcohol-induced atrial arrhythmias, is characterized by an acute cardiac rhythm and/or conduction disturbance associated with heavy ethanol consumption in a person without other clinical evidence of heart disease. (statpearls.com)
  • Objective To investigate the recovery process of exercise induced diastolic dysfunction in heart failure, using Doppler echocardiographic techniques. (bmj.com)
  • Conclusions Exercise induced diastolic left ventricular dysfunction of the failing heart persists for 24 hours or more after exercise. (bmj.com)
  • Diastolic ventricular function of the failing heart is reported to be impaired during exercise. (bmj.com)
  • 13 We further showed that the exercise induced diastolic dysfunction is attenuated by β adrenoceptor blockade. (bmj.com)
  • 14 Because diastolic ventricular function is sensitive to transient myocardial metabolic insults, these findings suggest that exercise exerts a harmful metabolic effect on the failing myocardium through sympathetic stimulation. (bmj.com)
  • Moreover, the exercise induced diastolic dysfunction may persist despite cessation of exercise. (bmj.com)
  • 15 Thus even a physiological sympathetic activation during exercise may cause a sustained diastolic dysfunction in the failing heart because of its susceptibility to sympathetic stimulation. (bmj.com)
  • Thus to determine a safe and logical exercise programme for patients with chronic heart failure it is important to clarify how long exercise induced diastolic dysfunction persists. (bmj.com)
  • Determine whether resting and exercise-induced increases in LV diastolic pressures are related to exaggerated right-left heart coupling and to increased afterload. (strokecenter.org)
  • The patient had a history of cardiomegaly with diastolic dysfunction and a bipolar disorder treated with lithium, lamotrigine, gabapentin. (swjpcc.com)
  • 4-6 Moreover, exercise training may in itself have deleterious effects on the failing myocardium, because of the presence of several intrinsic abnormalities susceptible to exercise induced sympathetic stimulation and consequent tachycardia. (bmj.com)
  • Myocardial tolerance to ischaemia/reperfusion (I/R) injury is improved by exercise training, but this cardioprotection is impaired by the chronic use of anabolic androgenic steroids (AAS). (nih.gov)
  • If this is the case, the harmful metabolic effects may accumulate during exercise training or even during daily physical activities, promoting progression of myocardial failure. (bmj.com)
  • and (3) while the training induction of myocardial hexokinase is inhibited by both beta 1- and beta 1 + beta 2-antagonists, myocardium may increase its ability to utilize lactate during exercise with training despite beta 1-blockade. (curehunter.com)
  • Since mitochondria are responsible for the production of ATP, agents that interfere with the physiological myocardial mitochondrial function are expected to induce depletion of ATP pool. (southlaketimes.com)
  • 1-3 However, exercise activates neurohumoral factors, reduces renal blood flow, and perhaps precipitates cardiac arrhythmias. (bmj.com)
  • However, his exercise tolerance was well. (springer.com)
  • Recent studies have shown unequivocally that exercise training for several months has beneficial effects on exercise tolerance, the autonomic nerve system, and the quality of life in patients with chronic heart failure. (bmj.com)
  • The clinical features of the human syndrome such as cardiomegaly, lung and peripheral oedema and decreased exercise tolerance should be present. (edu.au)
  • Change in sub-maximal exercise tolerance as evaluated using the Six Minute Walk test. (clinicaltrials.gov)
  • He had experienced dyspnea, decreased exercise tolerance and dizziness for one month. (accjournal.org)
  • Moreover, it has been reported that AASs can increase tolerance to exercise by making the muscles more capable to overload therefore shielding them from muscle fiber damage and improving the level of protein synthesis during recovery. (online-casino-player.info)
  • Here we report a case of a 20-year-old woman with a history of exercise intolerance since childhood that was misinterpreted as asthma until a 2D-Echo revealed ALCAPA with RCA collaterals to the left anterior descending artery, preserved LV ejection fraction, and absence of apparent mitral valve abnormality. (hindawi.com)
  • A 20-year-old woman presents with chronic dyspnea on exertion and exercise intolerance that was attributed to and treated as presumed exercise-induced asthma since childhood. (hindawi.com)
  • Right ventriculo-arterial uncoupling and impaired contractile reserve in obese patients with unexplained exercise intolerance. (harvard.edu)
  • A previously healthy African- American woman, aged 33 years, presented for urgent care with a three-week history of exercise and heat intolerance, dyspnea on exertion, chest pain, and a four-day history of lower-extremity edema and headaches. (ispub.com)
  • Muscle phosphofructokinase (PFK) deficiency (Tarui's disease), or glycogen storage disease type 7 (GSD7), is a rare form of glycogen storage disease characterized by exertional fatigue and muscular exercise intolerance. (mendelian.co)
  • The most common presenting complaints include exercise intolerance, as well as cough, dyspnea, and syncope. (vin.com)
  • Glycogen metabolism: Aerobic exercise is essential for intermittent or submaximal contraction. (medscape.com)
  • Lipid metabolism: Lipid is an important source of energy in sustained submaximal exercise (ie, exercise lasting longer than 40 min). (medscape.com)
  • Also known as athletic bradycardia, or exercise-induced cardiomegaly, Athlete's heart is generally considered benign, but may occasionally hide a serious medical condition, or may even be mistaken for one. (sciblogs.co.nz)
  • Voluntary apnea during breath-hold diving (BHD) induces cardiovascular changes including bradycardia, reduced cardiac output, and arterial hypertension. (biomedcentral.com)
  • Phosgene-induced leakage of fluid from capillaries into the pulmonary interstitium is normally opposed by lymphatic drainage from the parenchyma, but as the fluid leakage increases, normal drainage mechanisms become progressively overwhelmed. (fas.org)
  • Of participants, 24.9% had cardiomegaly according to the findings of CXR and 50.8% based on echocardiography. (ircmj.com)
  • Although CXR may not have the same diagnostic accuracy as echocardiography, its easy accessibility and high specificity in diagnosis of cardiomegaly is very helpful, which can play an important and a cost-benefit role, particularly in screening the enlarged heart size. (ircmj.com)
  • GE: Chest radiograph was normal with no cardiomegaly and normal lung fields. (bmj.com)
  • Any dyspnea on effort had not seen during out-patient clinic (NYHA I). Ventilation/perfusion lung scintigraphy was conducted to exclude aneurysm-induced compression of surrounding organs, but no significant findings were observed. (springer.com)
  • Exercise capacity, lung congestion, maximal oxygen consumption, arterial oxygen saturation, and survivorship were all improved in the iPS-treated cohort, which was free of adverse effects on follow-up. (ahajournals.org)
  • Platz E, Merz A, Silverman M, Lewis E, Groarke JD, Waxman A, Systrom D. Association between lung ultrasound findings and invasive exercise haemodynamics in patients with undifferentiated dyspnoea. (harvard.edu)
  • At 100 days post-TAC, untreated K ATP channel-deficient hearts developed cardiomegaly, regional and global left ventricular systolic dysfunction, fulminant congestive heart failure and death. (ahajournals.org)
  • The neuroprotective efficacy of induced hypothermia following or during ischemia of the brain is evident in experimental animal models of stroke [1 -1 1]. (google.com)
  • 1. Ischemia induces opening of the blood-brain barrier, a process that seems to be very sensitive to brain temperature [15]. (google.com)
  • After intravenous anesthesia, his aneurysm occluded the left main bronchus and right pulmonary artery simultaneously, and induced severe hypoxia. (springer.com)
  • Apnea, whether voluntary or involuntary, induces several physiological changes, which are a type of protective responses to hypoxia and involve potential health hazards as well. (biomedcentral.com)
  • Obstructive sleep apnea (OSA) is a condition in which breathing stops involuntarily for a short time during sleep, has something in common with BHD in terms of the repeated exposure to intermittent apnea-induced hypoxia, even though it's pathophysiology is different from what of BHD. (biomedcentral.com)
  • The chronic nandrolone treatment impairs the exercise-induced cardioprotection against ischaemia/reperfusion injury by activating the cardiac renin-angiotensin-aldosterone system and downregulating KATP channel expression. (nih.gov)
  • The athletes' ECG and the exercise related sudden cardiac death]. (cdc.gov)
  • Furthermore, as kidney function and cardiovascular disease are closely associated [ 16 - 18 ] and BHD induces cardiovascular changes, we hypothesize that renal impairment may be one of the potential long-term health risks of repetitive BHD. (biomedcentral.com)
  • Thoracic radiography is not specific for pulmonary hypertension, but may demonstrate supportive findings, including cardiomegaly, right-sided heart enlargement, or pulmonary artery dilation. (vin.com)
  • Nonetheless, it is noteworthy that sensitivity and specificity of CXR findings in the diagnosis of cardiomegaly were 34%, and 84.5%, respectively. (ircmj.com)
  • It is known that the glucocorticoid induced morphological changes are associated with cardiovascular risk factors such as high blood pressure, blood glucose and triglyceride levels, and low high density lipoprotein cholesterol levels, 6 and that many forms of lipodystrophy are associated with metabolic disorders and premature atherosclerosis. (bmj.com)
  • The combination of high glucose and low insulin can induce oxidative stress , which impairs cell remodeling, particularly in the absence of normal scavenger levels. (stylesstar.com)
  • 1 ] Right ventricular (RV) pacing can induce dyssynchronous contraction of the left ventricle (LV) and LV dysfunction. (accjournal.org)
  • Mixed or variable threshold angina pectoris is a syndrome in which there is substantial variation in the magnitude of physical activity that induces anginal chest pain. (wikidoc.org)
  • The pathophysiology of Holiday heart syndrome, or alcohol-induced arrhythmia, is complex, and therefore not completely understood. (statpearls.com)
  • 7-12 Thus we cannot exclude the possibility that exercise training worsens long term prognosis in patients with chronic heart failure despite the short term benefits. (bmj.com)
  • The present study evaluated whether blockade of angiotensin II receptor (AT1-R) with losartan and aldosterone receptor (mineralocorticoid receptor, MR) with spironolactone could prevent the deleterious effect of AAS on the exercise-induced cardioprotection. (nih.gov)
  • By contrast, the exercise induced dyspnoea and orthopnoea progressed to the point where his capacity to perform activities of daily living was impaired. (bmj.com)
  • Phosphofructokinase (PFK) Deficiency: Autosomal recessive disorder causing chronic hemolysis and hemolytic crises, especially with exercise. (animalia-life.club)
  • Anaerobic exercise may be substituted for high-intensity muscular activity, particularly when blood flow is reduced and oxygen availability is limited. (medscape.com)
  • Derived by nuclear reprogramming of somatic tissue, induced pluripotent stem (iPS) cells repair ischemic heart injury. (ahajournals.org)
  • The present invention relates to the induction of hypothermia in humans in a predictable and dose responsive fashion by use of a pharmaceutical composition comprising a neurotensin or a neurotensin analog or a synthetic neurotensin or a neurotensin receptor agonist, thereby inducing hypothermia, thus benefiting patients suffering from illnesses characterized by tissue anoxia. (google.com)
  • It contains two selenocysteine groups per molecule and is a major component of a redox system with a multiplicity of functions, among which is the capacity to degrade locally excessive and potentially toxic concentrations of peroxide and hydroperoxides likely to induce cell death and tissue atrophy ( 6 ). (fao.org)
  • 4 This typical redistribution of the adipose tissue induced by glucocorticoids can be considered as an iatrogenic form of lipodystrophy. (bmj.com)
  • In addition, the large areas of adrenergic denervation in the myocardium decrease the contractile reserve: an abnormal response to exercise in the presence of normal basal systolic function is a sign of incipient diabetic cardiomyopathy. (stylesstar.com)
  • Teir utility has become common in some forms of "small eyes" including botulinum toxin-induced lid ptosis. (vector-works.org)
  • A chest radiograph revealed marked cardiomegaly and mediastinum expansion without a difference of increased radiolucency between the left and right lungs. (springer.com)
  • An enlarged left ventricle could be caused by heart disease or harmless adaptation to sustained exercise, and these two conditions share overlapping features. (sciblogs.co.nz)
  • There is general consensus that HFpEF patients have increased left ventricular filling pressures (LVDP) and relatively normal systolic function at rest5,8,10, but two critical questions remain: what causes the increase in LVDP, and, are there important deficits in the cardiovascular response to exercise stress in HFpEF patients3,4? (strokecenter.org)
  • However, as dilatation progresses, left ventricular ejection fraction and stroke volume deteriorate during exercise and at rest, and finally pulmonary capillary wedge pressure increases and patients become symptomatic 1.5-3 years after the infarct. (ox.ac.uk)
  • However, transitory increases of pulmonary artery pressure may occur during exacerbations, exercise and sleep. (ersjournals.com)
  • It is noteworthy that cardiomegaly is developed by different diseases, including valvular heart diseases, IHD, and cardiomyopathy as well as pericardial diseases. (ircmj.com)
  • Consider conducting exercise stress tests for male FFs above the age of 45 years with two or more risk factors for CAD. (cdc.gov)
  • In one study reporting the etiology of palpitations, 43% were found to be of cardiac etiology, 31% of psychiatric etiology and approximately 10% were classified as miscellaneous (medication induced, thyrotoxicosis, caffeine, cocaine, anemia, amphetamine, mastocytosis). (wikipedia.org)