Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.Exercise Test: Controlled physical activity which is performed in order to allow assessment of physiological functions, particularly cardiovascular and pulmonary, but also aerobic capacity. Maximal (most intense) exercise is usually required but submaximal exercise is also used.Exercise Therapy: A regimen or plan of physical activities designed and prescribed for specific therapeutic goals. Its purpose is to restore normal musculoskeletal function or to reduce pain caused by diseases or injuries.Hydrops Fetalis: Abnormal accumulation of serous fluid in two or more fetal compartments, such as SKIN; PLEURA; PERICARDIUM; PLACENTA; PERITONEUM; AMNIOTIC FLUID. General fetal EDEMA may be of non-immunologic origin, or of immunologic origin as in the case of ERYTHROBLASTOSIS FETALIS.Cardiomegaly, Exercise-Induced: Heart enlargement and other remodeling in cardiac morphology and electrical circutry found in individuals who participate in intense repeated exercises.Exercise: Physical activity which is usually regular and done with the intention of improving or maintaining PHYSICAL FITNESS or HEALTH. Contrast with PHYSICAL EXERTION which is concerned largely with the physiologic and metabolic response to energy expenditure.Exercise Tolerance: The exercise capacity of an individual as measured by endurance (maximal exercise duration and/or maximal attained work load) during an EXERCISE TEST.Jamaica: An island in the Greater Antilles in the West Indies. Its capital is Kingston. It was discovered in 1494 by Columbus and was a Spanish colony 1509-1655 until captured by the English. Its flourishing slave trade was abolished in the 19th century. It was a British colony 1655-1958 and a territory of the West Indies Federation 1958-62. It achieved full independence in 1962. The name is from the Arawak Xaymaca, rich in springs or land of springs. (From Webster's New Geographical Dictionary, 1988, p564 & Room, Brewer's Dictionary of Names, 1992, p267)Radiography, Thoracic: X-ray visualization of the chest and organs of the thoracic cavity. It is not restricted to visualization of the lungs.Physical Exertion: Expenditure of energy during PHYSICAL ACTIVITY. Intensity of exertion may be measured by rate of OXYGEN CONSUMPTION; HEAT produced, or HEART RATE. Perceived exertion, a psychological measure of exertion, is included.Cardiomyopathies: A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).Arteriovenous Fistula: An abnormal direct communication between an artery and a vein without passing through the CAPILLARIES. An A-V fistula usually leads to the formation of a dilated sac-like connection, arteriovenous aneurysm. The locations and size of the shunts determine the degree of effects on the cardiovascular functions such as BLOOD PRESSURE and HEART RATE.Pericardial Effusion: Fluid accumulation within the PERICARDIUM. Serous effusions are associated with pericardial diseases. Hemopericardium is associated with trauma. Lipid-containing effusion (chylopericardium) results from leakage of THORACIC DUCT. Severe cases can lead to CARDIAC TAMPONADE.Chagas Cardiomyopathy: A disease of the CARDIAC MUSCLE developed subsequent to the initial protozoan infection by TRYPANOSOMA CRUZI. After infection, less than 10% develop acute illness such as MYOCARDITIS (mostly in children). The disease then enters a latent phase without clinical symptoms until about 20 years later. Myocardial symptoms of advanced CHAGAS DISEASE include conduction defects (HEART BLOCK) and CARDIOMEGALY.Fetal Diseases: Pathophysiological conditions of the FETUS in the UTERUS. Some fetal diseases may be treated with FETAL THERAPIES.Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.Electrocardiography: Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.Ultrasonography, Prenatal: The visualization of tissues during pregnancy through recording of the echoes of ultrasonic waves directed into the body. The procedure may be applied with reference to the mother or the fetus and with reference to organs or the detection of maternal or fetal disease.Echocardiography: Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.Heart Neoplasms: Tumors in any part of the heart. They include primary cardiac tumors and metastatic tumors to the heart. Their interference with normal cardiac functions can cause a wide variety of symptoms including HEART FAILURE; CARDIAC ARRHYTHMIAS; or EMBOLISM.Oxygen Consumption: The rate at which oxygen is used by a tissue; microliters of oxygen STPD used per milligram of tissue per hour; the rate at which oxygen enters the blood from alveolar gas, equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body. (Stedman, 25th ed, p346)Fatal Outcome: Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.Physical Endurance: The time span between the beginning of physical activity by an individual and the termination because of exhaustion.Heart Defects, Congenital: Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.Myocardium: The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.Muscle, Skeletal: A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.Heart Rate: The number of times the HEART VENTRICLES contract per unit of time, usually per minute.Bicycling: The use of a bicycle for transportation or recreation. It does not include the use of a bicycle in studying the body's response to physical exertion (BICYCLE ERGOMETRY TEST see EXERCISE TEST).Rest: Freedom from activity.Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.Physical Fitness: The ability to carry out daily tasks and perform physical activities in a highly functional state, often as a result of physical conditioning.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Prognosis: A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.Resistance Training: A type of strength-building exercise program that requires the body muscle to exert a force against some form of resistance, such as weight, stretch bands, water, or immovable objects. Resistance exercise is a combination of static and dynamic contractions involving shortening and lengthening of skeletal muscles.Running: An activity in which the body is propelled by moving the legs rapidly. Running is performed at a moderate to rapid pace and should be differentiated from JOGGING, which is performed at a much slower pace.Infant, Newborn: An infant during the first month after birth.Anaerobic Threshold: The oxygen consumption level above which aerobic energy production is supplemented by anaerobic mechanisms during exercise, resulting in a sustained increase in lactate concentration and metabolic acidosis. The anaerobic threshold is affected by factors that modify oxygen delivery to the tissues; it is low in patients with heart disease. Methods of measurement include direct measure of lactate concentration, direct measurement of bicarbonate concentration, and gas exchange measurements.Muscle Stretching Exercises: Exercises that stretch the muscle fibers with the aim to increase muscle-tendon FLEXIBILITY, improve RANGE OF MOTION or musculoskeletal function, and prevent injuries. There are various types of stretching techniques including active, passive (relaxed), static, dynamic (gentle), ballistic (forced), isometric, and others.Pulmonary Gas Exchange: The exchange of OXYGEN and CARBON DIOXIDE between alveolar air and pulmonary capillary blood that occurs across the BLOOD-AIR BARRIER.Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)Breathing Exercises: Therapeutic exercises aimed to deepen inspiration or expiration or even to alter the rate and rhythm of respiration.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Blood Pressure: PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.Physical Education and Training: Instructional programs in the care and development of the body, often in schools. The concept does not include prescribed exercises, which is EXERCISE THERAPY.Leg: The inferior part of the lower extremity between the KNEE and the ANKLE.Asthma, Exercise-Induced: Asthma attacks following a period of exercise. Usually the induced attack is short-lived and regresses spontaneously. The magnitude of postexertional airway obstruction is strongly influenced by the environment in which exercise is performed (i.e. inhalation of cold air during physical exertion markedly augments the severity of the airway obstruction; conversely, warm humid air blunts or abolishes it).Exercise Movement Techniques: Methods or programs of physical activities which can be used to promote, maintain, or restore the physical and physiological well-being of an individual.GlycogenRegional Blood Flow: The flow of BLOOD through or around an organ or region of the body.Weight Lifting: A sport in which weights are lifted competitively or as an exercise.Muscle Fatigue: A state arrived at through prolonged and strong contraction of a muscle. Studies in athletes during prolonged submaximal exercise have shown that muscle fatigue increases in almost direct proportion to the rate of muscle glycogen depletion. Muscle fatigue in short-term maximal exercise is associated with oxygen lack and an increased level of blood and muscle lactic acid, and an accompanying increase in hydrogen-ion concentration in the exercised muscle.Adaptation, Physiological: The non-genetic biological changes of an organism in response to challenges in its ENVIRONMENT.Muscle Strength: The amount of force generated by MUSCLE CONTRACTION. Muscle strength can be measured during isometric, isotonic, or isokinetic contraction, either manually or using a device such as a MUSCLE STRENGTH DYNAMOMETER.Energy Metabolism: The chemical reactions involved in the production and utilization of various forms of energy in cells.Cardiac Output: The volume of BLOOD passing through the HEART per unit of time. It is usually expressed as liters (volume) per minute so as not to be confused with STROKE VOLUME (volume per beat).Hemodynamics: The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.Walking: An activity in which the body advances at a slow to moderate pace by moving the feet in a coordinated fashion. This includes recreational walking, walking for fitness, and competitive race-walking.Sports: Activities or games, usually involving physical effort or skill. Reasons for engagement in sports include pleasure, competition, and/or financial reward.Respiration: The act of breathing with the LUNGS, consisting of INHALATION, or the taking into the lungs of the ambient air, and of EXHALATION, or the expelling of the modified air which contains more CARBON DIOXIDE than the air taken in (Blakiston's Gould Medical Dictionary, 4th ed.). This does not include tissue respiration (= OXYGEN CONSUMPTION) or cell respiration (= CELL RESPIRATION).Ergometry: Any method of measuring the amount of work done by an organism, usually during PHYSICAL EXERTION. Ergometry also includes measures of power. Some instruments used in these determinations include the hand crank and the bicycle ergometer.Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.Oxygen: An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.Cardiovascular Physiological Phenomena: Processes and properties of the CARDIOVASCULAR SYSTEM as a whole or of any of its parts.Analysis of Variance: A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.Blood Glucose: Glucose in blood.Quadriceps Muscle: The quadriceps femoris. A collective name of the four-headed skeletal muscle of the thigh, comprised of the rectus femoris, vastus intermedius, vastus lateralis, and vastus medialis.Motor Activity: The physical activity of a human or an animal as a behavioral phenomenon.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Dyspnea: Difficult or labored breathing.Lactates: Salts or esters of LACTIC ACID containing the general formula CH3CHOHCOOR.Stroke Volume: The amount of BLOOD pumped out of the HEART per beat, not to be confused with cardiac output (volume/time). It is calculated as the difference between the end-diastolic volume and the end-systolic volume.Respiratory Function Tests: Measurement of the various processes involved in the act of respiration: inspiration, expiration, oxygen and carbon dioxide exchange, lung volume and compliance, etc.Cross-Over Studies: Studies comparing two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. In the case of two treatments, A and B, half the subjects are randomly allocated to receive these in the order A, B and half to receive them in the order B, A. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. (Last, A Dictionary of Epidemiology, 2d ed)Swimming: An activity in which the body is propelled through water by specific movement of the arms and/or the legs. Swimming as propulsion through water by the movement of limbs, tail, or fins of animals is often studied as a form of PHYSICAL EXERTION or endurance.Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.Sweating: The process of exocrine secretion of the SWEAT GLANDS, including the aqueous sweat from the ECCRINE GLANDS and the complex viscous fluids of the APOCRINE GLANDS.Carbon Dioxide: A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.Heart: The hollow, muscular organ that maintains the circulation of the blood.Forearm: Part of the arm in humans and primates extending from the ELBOW to the WRIST.Single-Blind Method: A method in which either the observer(s) or the subject(s) is kept ignorant of the group to which the subjects are assigned.Phosphocreatine: An endogenous substance found mainly in skeletal muscle of vertebrates. It has been tried in the treatment of cardiac disorders and has been added to cardioplegic solutions. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1996)Respiratory Mechanics: The physical or mechanical action of the LUNGS; DIAPHRAGM; RIBS; and CHEST WALL during respiration. It includes airflow, lung volume, neural and reflex controls, mechanoreceptors, breathing patterns, etc.Isometric Contraction: Muscular contractions characterized by increase in tension without change in length.Body Composition: The relative amounts of various components in the body, such as percentage of body fat.Hand Strength: Force exerted when gripping or grasping.Fatigue: The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.Citrate (si)-Synthase: Enzyme that catalyzes the first step of the tricarboxylic acid cycle (CITRIC ACID CYCLE). It catalyzes the reaction of oxaloacetate and acetyl CoA to form citrate and coenzyme A. This enzyme was formerly listed as EC 4.1.3.7.Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.Insulin: A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.Athletes: Individuals who have developed skills, physical stamina and strength or participants in SPORTS or other physical activities.Quality of Life: A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral and social environment; the overall condition of a human life.Fatty Acids, Nonesterified: FATTY ACIDS found in the plasma that are complexed with SERUM ALBUMIN for transport. These fatty acids are not in glycerol ester form.Plasma Volume: Volume of PLASMA in the circulation. It is usually measured by INDICATOR DILUTION TECHNIQUES.Physical Therapy Modalities: Therapeutic modalities frequently used in PHYSICAL THERAPY SPECIALTY by PHYSICAL THERAPISTS or physiotherapists to promote, maintain, or restore the physical and physiological well-being of an individual.Dietary Carbohydrates: Carbohydrates present in food comprising digestible sugars and starches and indigestible cellulose and other dietary fibers. The former are the major source of energy. The sugars are in beet and cane sugar, fruits, honey, sweet corn, corn syrup, milk and milk products, etc.; the starches are in cereal grains, legumes (FABACEAE), tubers, etc. (From Claudio & Lagua, Nutrition and Diet Therapy Dictionary, 3d ed, p32, p277)Epinephrine: The active sympathomimetic hormone from the ADRENAL MEDULLA. It stimulates both the alpha- and beta- adrenergic systems, causes systemic VASOCONSTRICTION and gastrointestinal relaxation, stimulates the HEART, and dilates BRONCHI and cerebral vessels. It is used in ASTHMA and CARDIAC FAILURE and to delay absorption of local ANESTHETICS.Obesity: A status with BODY WEIGHT that is grossly above the acceptable or desirable weight, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).Reference Values: The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.Double-Blind Method: A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Body Temperature Regulation: The processes of heating and cooling that an organism uses to control its temperature.Body Temperature: The measure of the level of heat of a human or animal.Athletic Performance: Carrying out of specific physical routines or procedures by one who is trained or skilled in physical activity. Performance is influenced by a combination of physiological, psychological, and socio-cultural factors.Forced Expiratory Volume: Measure of the maximum amount of air that can be expelled in a given number of seconds during a FORCED VITAL CAPACITY determination . It is usually given as FEV followed by a subscript indicating the number of seconds over which the measurement is made, although it is sometimes given as a percentage of forced vital capacity.Weight Loss: Decrease in existing BODY WEIGHT.Vascular Resistance: The force that opposes the flow of BLOOD through a vascular bed. It is equal to the difference in BLOOD PRESSURE across the vascular bed divided by the CARDIAC OUTPUT.Pulmonary Disease, Chronic Obstructive: A disease of chronic diffuse irreversible airflow obstruction. Subcategories of COPD include CHRONIC BRONCHITIS and PULMONARY EMPHYSEMA.Recovery of Function: A partial or complete return to the normal or proper physiologic activity of an organ or part following disease or trauma.Ventricular Function, Left: The hemodynamic and electrophysiological action of the left HEART VENTRICLE. Its measurement is an important aspect of the clinical evaluation of patients with heart disease to determine the effects of the disease on cardiac performance.Patient Compliance: Voluntary cooperation of the patient in following a prescribed regimen.Angina Pectoris: The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION.Hyperemia: The presence of an increased amount of blood in a body part or an organ leading to congestion or engorgement of blood vessels. Hyperemia can be due to increase of blood flow into the area (active or arterial), or due to obstruction of outflow of blood from the area (passive or venous).Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Thigh: The portion of the leg in humans and other animals found between the HIP and KNEE.Intermittent Claudication: A symptom complex characterized by pain and weakness in SKELETAL MUSCLE group associated with exercise, such as leg pain and weakness brought on by walking. Such muscle limpness disappears after a brief rest and is often relates to arterial STENOSIS; muscle ISCHEMIA; and accumulation of LACTATE.Sedentary Lifestyle: Usual level of physical activity that is less than 30 minutes of moderate-intensity activity on most days of the week.Altitude: A vertical distance measured from a known level on the surface of a planet or other celestial body.Blood Flow Velocity: A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.Tai Ji: One of the MARTIAL ARTS and also a form of meditative exercise using methodically slow circular stretching movements and positions of body balance.Bed Rest: Confinement of an individual to bed for therapeutic or experimental reasons.Muscle Proteins: The protein constituents of muscle, the major ones being ACTINS and MYOSINS. More than a dozen accessory proteins exist including TROPONIN; TROPOMYOSIN; and DYSTROPHIN.Sympathetic Nervous System: The thoracolumbar division of the autonomic nervous system. Sympathetic preganglionic fibers originate in neurons of the intermediolateral column of the spinal cord and project to the paravertebral and prevertebral ganglia, which in turn project to target organs. The sympathetic nervous system mediates the body's response to stressful situations, i.e., the fight or flight reactions. It often acts reciprocally to the parasympathetic system.Blood Gas Analysis: Measurement of oxygen and carbon dioxide in the blood.Hyperventilation: A pulmonary ventilation rate faster than is metabolically necessary for the exchange of gases. It is the result of an increased frequency of breathing, an increased tidal volume, or a combination of both. It causes an excess intake of oxygen and the blowing off of carbon dioxide.Arm: The superior part of the upper extremity between the SHOULDER and the ELBOW.Respiratory Muscles: These include the muscles of the DIAPHRAGM and the INTERCOSTAL MUSCLES.

The incognita of the known: the athlete's heart syndrome. (1/17)

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The prevalence, distribution, and clinical outcomes of electrocardiographic repolarization patterns in male athletes of African/Afro-Caribbean origin. (2/17)

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Eccentric and concentric cardiac hypertrophy induced by exercise training: microRNAs and molecular determinants. (3/17)

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Chronic Akt blockade aggravates pathological hypertrophy and inhibits physiological hypertrophy. (4/17)

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Gene deletion of P2Y4 receptor lowers exercise capacity and reduces myocardial hypertrophy with swimming exercise. (5/17)

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Pathological role of serum- and glucocorticoid-regulated kinase 1 in adverse ventricular remodeling. (6/17)

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The endurance athletes heart: acute stress and chronic adaptation. (7/17)

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Atrial fibrillation and atrial flutter in athletes. (8/17)

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Limited microRNAs (miRNAs, miRs) have been reported to be necessary for exercise-induced cardiac growth and essential for protection against pathological cardiac remodeling. Here we determined members of the miR-17-92 cluster and their passenger miRNAs expressions in two distinct murine exercise models and found that miR-17-3p was increased in both. miR-17-3p ... read more promoted cardiomyocyte hypertrophy, proliferation, and survival. TIMP-3 was identified as a direct target gene of miR-17-3p whereas PTEN was indirectly inhibited by miR-17-3p. Inhibition of miR-17-3p in vivo attenuated exercise-induced cardiac growth including cardiomyocyte hypertrophy and expression of markers of myocyte proliferation. Importantly, mice injected with miR-17-3p agomir were protected from adverse remodeling after cardiac ischemia/reperfusion injury. Collectively, these data suggest that miR-17-3p contributes to exercise-induced cardiac growth and protects against adverse ventricular remodeling. miR-17-3p may ...
Exercise-induced cardiac growth factors govern c-kitpos endogenous cardiac stem-progenitor cell growth and differentiation in vitro. (A-F) Histogram plots and
Patients with chronic kidney disease have profound exercise intolerance which contributes to an increased risk of cardiovascular disease. The investigators have found that chronic kidney disease patients have an exaggerated increase in blood pressure during certain forms of exercise that could certainly contribute to exercise dysfunction as well as cardiovascular risk. The investigators will test the mechanisms underlying this exaggerated blood pressure response, as well as the potential benefits of short-term tetrahydrobiopterin (BH4) with folic acid on both exercise dysfunction and cardiovascular risk factors in chronic kidney disease. The investigators will test whether short-term treatment with tetrahydrobiopterin (BH4), a cofactor for nitric oxide, together with folic acid improves inflammation, vascular health, and adrenaline levels, both at rest and during exercise in chronic kidney disease ...
(HealthDay)-Sleep-disordered breathing (SDB) severity is associated with lower functional aerobic capacity (FAC) and increased blood pressure, according to a study published in the June 1 issue of The American Journal of ...
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The objective of this work is to study in cardiac MRI the difference between the physiological hypertrophy of the myocardium of the athletes heart and the hypertrophy of the pathological myocardium by comparing athletes (athlete group) to a group of subjects. non-athlete followed for HCM (HCM group).Material and methodsWe conducted a prospective comparative study including 61 subjects. The group of athletes comprised 31 subjects. TheHCM group consisted of 30 subjects. All subjects were paired to age and body surface and had cardiac MRI with the late enhancement study.ResultsThe thickness of the LV wall (mea ...
Learn about the causes, symptoms, diagnosis & treatment of Sports and the Heart from the Professional Version of the Merck Manuals.
TY - JOUR. T1 - Reduced ischemia and reperfusion injury following exercise training. AU - Libonati, Joseph R.. AU - Gaughan, John P.. AU - Hefner, Colleen A.. AU - Gow, Andrew. AU - Paolone, Albert M.. AU - Houser, Steven R.. PY - 1997. Y1 - 1997. N2 - We examined the effects of two exercise training modalities, i.e., low intensity endurance and sprint running, on in vitro, isovolumic myocardial performance following ischemia and reperfusion. Rats ran on a treadmill 5 d · wk-1 for 6 wk at the following levels: endurance; 20 m · min-1, 0% grade, 60 min · d-1 and sprint; five 1-min runs at 75 m · min-1, 15% grade interspersed with 1-min active recovery runs at 20 m · min-1, 15% grade. Both endurance and sprint training significantly improved exercise tolerance relative to control (P ,0.05) on two graded exercise tests. Buffer perfused hearts of control (N = 18), endurance (N = 20), and sprint (N = 13) trained animals underwent no-flow ischemia (20 min) and reperfusion (30 min) in a ...
What is driving the exaggerated blood pressure response to exercise in patients with peripheral arterial disease (PAD)? In this podcast, Editor in Chief Irving H. Zucker (University of Nebraska Medical Center) interviews senior author Gail Thomas (Penn State College of Medicine) and content expert Hanjun Wang (University of Nebraska Medical Center) about the unique study by Kuczmarski et al. Thomas and co-authors used telemetry to record blood pressure during exercise in conscious animals, both before and after bi-lateral femoral artery ligation. The studied was conducted over a period of two months, a technical success given that the authors used chronically-instrumented conscious animals. Thomas and collaborators found that the blood pressure response was exaggerated as early as 3 days after femoral artery ligation and lasted for the duration of the experiment in both female and male mice. Are the mechanisms that play a role in blood pressure response to short-term ligation, such as cytokines ...
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To the Editor: The role of adults as reservoirs of pertussis was previously well established (1-7). Young army recruits undergoing basic training in the Israeli Defense Force constitute a unique adult population because of their special living and service conditions. This and the fact that they are not vaccinated with the diphtheria, tetanus, and pertussis (DTP) vaccine after the age of 1 year (unlike children in most of the Western countries) led us to hypothesize that this semiclosed population may have an exceptionally high risk for pertussis. These young soldiers are on leave on weekends, during which time they come in close contact with susceptible family members, including young infants, and may thus facilitate the "import" and "export" of pertussis between the military setting and the general population. An outbreak of pertussis that recently occurred among infantry soldiers (8) indicated the need to conduct the present study, in which we sought to evaluate the prevalence and incidence of ...
The world s oldest marathon runner has revealed that he will be retiring at the age of 101 years after one final run in Hong Kong next month.
The average athletes heart rate during a marathon is 160 beats per minute. Thats based on a person in his or her 20s who has a resting heart rate of 55 bpm and a maximum heart rate of 200 bpm. A ...
Our Heart & Vascular Center offers dedicated heart rhythm suites and the most advanced technology to detect and treat irregular heart patterns.
From diet to weekly exercise regimes and everything in between, Harlequins coach Adam Bishop gives loaded the lowdown on what is expected at the elite level
I have been running for years and started running marathons in the past 3 years. My 16-year-old son finished the Napa Valley Marathon with me. He started running 8 months ago as a way to lose weight. I have consistently asked him if he wanted to go running, but he was never interested before. My wife and I thought the marathon training was a one off; hed do it and thatd it. He finished in 3:15 and now he wants to runs 2-4 marathons a year. Hes running track in high school for the first time right now (1600 and 3200 meters).
Im not sure yet. I will be running a marathon the weekend before, so it depends on how my legs feel. I intend to run full out at this marathon. I have a few friends that will be running the SFM so Im thinking of doing the second half (because the first half is just TOO EARLY!) as a fun run and enjoying yet another race experience. Plus it was my very first 1/2 marathon I did...would be nice to start a tradition!. ...
In 2007 I ran the marathon to celebrate my 30th birthday and raise money for St. Elizabeths Hospice, Ipswich, who cared for my Dad in his last few days. Needless to say I am not a natural runner and the experience is one I will never forget.. Prepare yourself for blood, sweat and tears... Wednesday 27th December 2006 20 Minutes approx. 3.21km (On Treadmill). First day of training today. This time yesterday I was eating my second Christmas dinner! Anyway, was able to complete 20 minutes on the treadmill at 10km/hr comfortably so a good start. However, it will be much harder out on the roads so I can look forward to that!. Thursday 28th December 2006 30 Minutes approx. 2.3km. First run outside and started off quite well although I think I started off too fast. Wanted to die after the first very slight hill! I ran round the Orwell Country Park, which was a bit too muddy and slippery. I couldnt complete the 30 minutes; I had to walk one bit of my route (which was uphill and muddy) but then ...
Kenyan distance runners won both the mens and womens divisions of Sundays New York City Marathon. A Harvard evolutionary biologist suggests some possible reasons why.
Now I find myself slowing down, but going much longer distances. I guess Im really becoming an ultramarathoner. Its funny how after two marathons, I still didnt see myself as a marathoner or even a "real" runner. Since then, I have run about 7 ultras and now across the state of Iowa and Im now thinking I might be an ultramarathoner. Its funny how my past can play such a big part of my view of my world and my future ...
As Mo Farahs collapse at the New York half marathon shows how tough long distance running can be, meet Tony The Fridge Morrison, who runs with a 42kg refrigerator strapped to his back
A month after giving birth to our first child, my wife, Macy, had a crazy idea. She wanted to set a personal best in the marathon. And she wanted to do it soon.
Running long-distance races isn't going to hurt your heart any more than other vigorous sports, researchers say. Just make sure you're fit enough
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MATTHEWS, N.C. -- A North Carolina mom is thriving once again after losing three limbs to the flu just two years ago. In 2013, Kristan Seaford caught a bad case of the flu that turned into sepsis and nearly killed her, according to WCNC.
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FORT BENNING, Ga. (AP) - The young Army infantry recruits lined up in full combat gear, guns at the ready. At the signal, a soldier in front kicked in the door and they burst into the room, swiveling to check around the walls for threats. Youre dead! one would-be enemy yelled out from a dark corner, the voice slightly higher than the others echoing through the building. It was 18-year-old Kirsten, training to become one of the Armys first women serving as infantry soldiers.
FORT BENNING, Ga. (AP) - The young Army infantry recruits lined up in full combat gear, guns at the ready. At the signal, a soldier in front kicked in the door and they burst into
WASHINGTON, Sept. 17.―Falling from a height of 75 feet, Orville Wright and Lieut. Thomas E. Selfridge of the Signal Corps were buried in the wreckage of Wrights aeroplane shortly after 5 oclock this afternoon. The young army officer died at 8:10 oclock to-night. Wright is badly hurt, although he probably will recover. The flying machine is a mass of tangled wires, torn and twisted planes, and tattered canvas. The accident was due to the breaking of one of the blades of the propeller on the left side.. Although there had been but a handful of people at the aeronautical testing grounds at Fort Myer during the last few days, fully 2,000 had gathered by 4:30 this afternoon. The aeroplane was still in its shed, but Mr. Wright arrived a few minutes later and ordered it taken to the northern end of the field, to be placed on the starting track in readiness for a flight.. Selfridge In First.. Everybody was ordered back from the machine, and Mr. Wright turned to Lieut. Selfridge and said: "You might ...
See this site. Do not be tempted. It used to be called hillbilly heroin, before it became the drug of choice for older professional males.
I was always better at sprinting than running long distance--back in the days when I actually ran...in high shcool. My wife, by way of contrast, was and is a marathon runner. One of the things that Ive noticed as I have watched her run over the years is that she knows how to pace herself.
Another way to estimate is to look at the typical slowdown from 10K pace to marathon pace, which for world-class marathon runners is usually around 24 seconds per mile (6 seconds per 400m) to 28 seconds per mile (7 seconds per 400m). Bekele just ran a marathon at just under 70.0 seconds per 400m, which would work out to a 10K between 26:15 (63 sec pace) and 26:40 (64 sec pace)….while Mo Farah has a 10K PR of 26:46 ...
The best compression arm sleeves to promote blood flow and circulation for running, crossfit training, ultra runners, marathon runners, and triathletes. Also great for obstacle race running and trail running.
So why do I feel the need to write this all out? Because it drives me mad that people, who have no idea what its like to have cancer, feel like they can call people, who are fighting for their lives, liars because we dont look "sick enough." Why do I have to look "sick" for you to believe me? First, what does sick look like? And why is it that me looking sick would make you feel more comfortable? Does it make you uncomfortable because if a normal looking girl can get cancer, that means that you could too? You could. Anyone can get cancer. It does not care how old, young, strong, healthy, you are. You could be a vegan marathon runner and somehow still end up with cancer. Anyone could have or get cancer ...
Just in case your feet were feeling the need to get moving (maybe this 91-year-old marathon runner was some inspiration?), today just happens to be National...
Background: Hypertensive patients with large blood pressure (BP) variability have greater risks of cardiovascular events and exaggerated end-organ damages. Recently, we have shown that acute pressure overload triggers transient perivascular inflammation.. Hypothesis: We assessed the hypothesis that large BP variability exaggerates hypertensive cardiac remodeling through the activation of myocardial inflammation.. Methods and Results: A new rat model of chronic hypertension with exaggerated BP variability was created by performing bilateral sino-aortic denervation (SAD) in spontaneous hypertensive rats (SHRs). Seven weeks after SAD (n=10) or sham (n=7) operation (week 7), 24-hour BP was monitored telemetrically in SAD+SHRs and sham+SHRs. Although mean BP was similar in the two groups, SAD+SHRs had greater BP variability (larger standard deviation and covariance of mean BP), compared with sham+SHRs. Both the two groups showed concentric left ventricular (LV) hypertrophy, and SAD aggravated LV ...
Totally, 142 HF patients with midrange ejection fraction (HFmrEF) and reduced ejection fraction (HFrEF) were enrolled in the study. There was a significantly correlation both between the EF and the EPSS and between the EF and the LVIDd/EPSS (P,0.001). In both HFmrEF and HFrEF groups, the correlation between the LVIDd/EPSS and the EF was more significant than was the correlation between the EPSS and the EF (P,0.001). The results of the linear regression analysis indicated that the LVIDd/EPSS was an independent predictor of the HFmrEF and the HFrEF (P,0.001). In the patients with EPSS≤12, there was a significant association between the EF and the LVIDd/EPSS (P,0.001) but not between the EF and the EPSS(P,0.05). The receiver operating characteristic curve analysis showed that the LVIDd/EPSS predicted advanced HF with 87% sensitivity and 72% specificity, using a cutoff value of 3.35,and it predicted the HFrEF (EF,40%) with 84% sensitivity and 81% specificity, using a cutoff value of 3.75.. ...
Were the only UK clinic offering Tecar Therapy to Marathon Runners, Triathletes, Cyclists, Iron Men and Martial Artists - record recovery speeds are possible using specialist technology and years of experience in diagnosis and treatments.
Thank you for your interest in spreading the word on Circulation.. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address. ...
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showcasing a graphic spade heart pattern, these pop top gloves are crafted of a soft (and cozy) stockinette stitch. wear them as mittens and button back the tops when you need free fingers for texting.
Two miles earlier I would have scoffed at the preposterous thought of running 2 miles at that pace. Things had changed, however, and all of a sudden I felt really calm and relaxed, and I just knew I would do it. I knew it would hurt, I knew it would be by far the best finish I had ever produced in a marathon, but I was in The Zone, and I wasnt going to snap out of it. I still kept passing runner after runner, and I knew that I would be able to push on until the end. The last mile finally spots a decent number of spectators, and they finally made some noise, which was good. It was just after the 25 mile marker, with a mile to go, that I got hit by the first cramp. In my last marathon, in Loch Ness, a similar thing had happened over the last two miles, and I had slowed down a lot. This time it was different, however; the cramps were not caused by mere fatigue but by the fact that I was basically running faster than my body was able to do for a sustained period of time. However, the cramps never ...
cardiomegaly - MedHelps cardiomegaly Center for Information, Symptoms, Resources, Treatments and Tools for cardiomegaly. Find cardiomegaly information, treatments for cardiomegaly and cardiomegaly symptoms.
The focus of our laboratory is heart function and exercise. Key questions we are trying to answer include: • what are the cardiac consequences of excessive exercise performed over a lifetime • what are the mechanisms of exercise-induced cardiac fatigue • how does the heart adapt to acute and chronic exercise in health and disease We have an interest in the spectrum of health, from long-standing athletes to clinical populations including heart failure, hypertension and atrial fibrillation.
Greg McQuaid has been running a marathon every weekend for the past 33 weeks. On Sunday, hell attempt to keep his streak going in Santa Rosa.
We are grateful to each and every one of you for the hours of training youve put in and the fundraising activities youve organised - not to mention the impressive sponsorship youve secured. We hope you are now feeling excited about the big day - we will be there cheering you on and we hope the knowledge that you are helping so many people affected by the most common blood cancer spurs you on if things get tough. We really couldnt do what we do without you! Our 2019 #TeamLymphoma runners are:
Sigma-Aldrich offers abstracts and full-text articles by [Viola Grabs, Tobias Peres, Otto Zelger, Bernhard Haller, Axel Pressler, Siegmund Braun, Martin Halle, Johannes Scherr].
Results Application of the 2010 ESC criteria, compared with the 2005 criteria, reduced the number of participants with abnormal ECG findings from 83/508 (16.3%) to 49/508 (9.6%). The reduction in the number of abnormal ECGs was driven by the reclassification of participants with isolated QRS voltage criteria for left ventricular hypertrophy from abnormal to normal. Of the 49 participants with abnormal ECGs, 14/49 (29%) had a single ECG abnormality and 35/49 (71%) had two or more abnormalities. The use of the 2010 criteria was associated with improved specificity (reduction in the false positive rate) and preserved sensitivity when compared with the 2005 criteria. ...
Choline supplementation may provide benefits for stamina athletes such as for example marathon runners, in addition to more casual sports athletes, by avoiding
Three years ago, I signed up for the Dublin City Marathon. We did a fundraiser for Special Olympics Ireland and had about 35 people running, virtually all of us first-time marathon runners. I broke the four hours so I was pleased about that.. ...
www.ncbi.nlm.nih.gov/pubmed/22002517 Probably nothing terribly new here. You cannot be a powerlifter and a marathon runner, or at least not good at both. Found this interesting t, team42470board
Recalling my most fit season of life, I realized I had been neglecting fitness care. As a pedestrian, I havent necessarily needed to do much intentional cardio to stay shapely, but I remembered how much I loved running before I had Aviel. As I researched adrenal fatigue, which is how I have been "self-treating" prior to discovery that my Cushings is adenoma related, I learned that running actually puts stress on the body and causes a release of cortisol. Its not necessarily recommended for those struggling with adrenal problems, but I departed from the suggestion and went for it. My logic is that the good endorphins are worth the small amount of stress. Im not a marathon runner... just 20 minutes at a time. And I think this was a good choice. I feel so much better when Im running regularly. It builds my confidence to meet my goals, and it increases my energy through out the day. I really do have this sense that I am more than a conqueror. For that, it is totally worth it ...
About Cardiomegaly - Welcome to my allnursesPage! You can learn all about me here. Together, we can learn, share, and network with nurses and nursing students from all around the world.
The influence of physiological cardiac hypertrophy on the concentration of plasma atrial natriuretic peptide was studied in six male athletes and six normally active, matched control men. They were examined by echocardiography during a graded exercise test on a bicycle ergometer. Plasma atrial natriuretic peptide was measured at rest, at each workload until exhaustion, and 15 and 30 minutes after the exercise test. Echocardiography showed that the athletes had a significantly larger left atrium, left ventricular end diastolic diameter, left ventricular posterior wall, interventricular septum, left ventricular ejection fraction, and left ventricular mass than the controls. The athletes performed significantly more work than the control group--325 W v 277 W. The plasma concentration of atrial natriuretic peptide rose by a mean factor of 2.76 (range 1.78-4.28) in all men from rest to maximum exercise. There were no differences between the athletes and the controls in the concentrations of plasma ...
Kenyan Olympic marathon runner Samuel Wanjiru died in the early hours of Monday morning, May 16, from injuries after a fall from the balcony of his first-floor Nyahururu home near the Rift Valley in central Kenya.
BACKGROUND: Interpretation of the athletes ECG is based on differentiation between benign ECG changes and potentially pathological abnormalities. The aim of the study was to compare the 2010 European Society of Cardiology (ESC) and the 2017 International criteria for differential diagnosis between hypertrophic cardiomyopathy (HCM) and athletes heart. METHODS: The study populations included 200 patients with HCM and 563 athletes grouped as follows: group 1, including normal ECG and isolated increase of QRS voltages, which are considered non-pathologic according to ESC and International criteria; group 2, including left atrial enlargement or left axis deviation in isolation and Q-waves with an amplitude ≥4 mm but ,25% of the ensuing R-wave and a duration ,0 ...
The most disturbing aspect of Cystic Fibrosis (CF) is the associated premature death. Low exercise capacity predicts death in patients with CF and is also associated with a steeper decline in lung function and more lung infections. A critical barrier to improving exercise tolerance in patients with CF is the investigators lack of knowledge regarding the different physiological mechanisms which contribute to their lower exercise capacity. We have compelling data to indicate that the blood vessels may contribute to the low exercise capacity in CF. The impact of this proof of concept investigation will test Phosphodiesterase Type 5 inhibitors (PDE5) inhibitors as a potential therapy in CF and will explore blood flow and endothelial function as potential mechanisms which contribute to exercise intolerance in CF. Improvements in exercise capacity will not only contribute to a better quality of live for patients with CF, it will also increase longevity in these patients ...
Methods This was a prospective observational study of the Parachute (n=734), Guards (n=1044), Line (n=3472) and Gurkha (n=458) Regiments of the British Army recruits during a 26-week basic military training programme over a 2-year period. The participant demographic characteristics were: age 18.9 years (SD±2.3), height 176.5 cm (SD±7.80), mass 69 kg (SD±9.7) and body mass index 22.14 kg/m2 (SD±2.5). ...
Heart stent effectiveness questioned. In a new study, 200 people with chest pain were randomly assigned to either receive a stent, which requires a surgical procedure or undergo a placebo procedure in which the doctors only threaded a catheter through without inserting a stent. Six weeks later, they evaluated all of the people on a treadmill test. There were no significant differences in how much exercise the two groups could do, or in how much chest pain they reported. The findings of the study raise questions about whether or not stents should be used as often, or at all, to treat chest pain. Chest pain can also be a sign of a heart attack. Read up on the other warning signs of a heart attack here. (NYT). A new recovery method for runners discovered. Researchers at the Karolinska Institute in Sweden published a new study in the Journal of Physiology that tested how best to help tired muscles recover after draining workouts and competitions. Several fit participants were instructed to do ...
When 16-year-old Wed Leonard suddenly died right after hitting the winning shot in his Michigan high school basketball game, doctors say he had an enlarged heart.
Win: You`ve probably heard of carbohydrate loading, something a lot of runners do before a race.Marathon runner Pat Hatz finds that eating a carbohydrate meal--such as pasta--the night before the
The man who ran the first marathon, the Greek soldier Pheidippides, dropped dead as he arrived in Athens with news of victory. We werent meant to run marathons.. Youve heard about young, seemingly healthy marathon runners suddenly dying during their races. And yet people still run to "be healthy.". Thats crazy right?. Take Normann Stadler for example. Stadler was a previous Ironman winner and serious cardio enthusiast. In 2011, he underwent emergency surgery to repair an enormous aortic aneurysm. He had ruined his heart by doing too much cardio.. John Mandrola, a heart doctor, said "Studies have shown elevated levels of coronary plaque in serial marathoners - a problem that rigorous exercise theoretically could cause. Heart disease comes from inflammation and if youre constantly, chronically inflaming yourself, never letting your body heal, why wouldnt there be a relationship between over exercise and heart disease?". Kelly Barrett, a 43 year old mother of 3 suffered from cardiac arrest ...
Hello! Im Megan, a recovering marathon runner (15 full marathons, countless halves and one ultra), school counselor and recently converted dog-lover from California. The year 2013 held both the highest and lowest points of my life. I was swept away on a surprise trip to Rome and proposed to in front of the Trevi Fountain, only to be hit a few months later with the sudden news that my Mom had stage IV cancer and needed emergency surgery. Still reeling from this, we planned my dream wedding, and embarked on the journey to become parents. I loved telling my Mom that I was pregnant from our 2nd IVF. She died the day after we heard the heartbeat for the first time, 10/8/14. I had our baby girl in May, 2015 and my life is now complete. Cant wait to show her the world! We took her to Vienna, Prague and Budapest in the summer of 2016 and we were in Venice and Milan for Christmas 2016. Our 3rd round of IVF in the fall of 2016 resulted in a pregnancy, but devastatingly, at 17 weeks pregnant I went for a ...
Hello! Im Megan, a recovering marathon runner (15 full marathons, countless halves and one ultra), school counselor and recently converted dog-lover from California. The year 2013 held both the highest and lowest points of my life. I was swept away on a surprise trip to Rome and proposed to in front of the Trevi Fountain, only to be hit a few months later with the sudden news that my Mom had stage IV cancer and needed emergency surgery. Still reeling from this, we planned my dream wedding, and embarked on the journey to become parents. I loved telling my Mom that I was pregnant from our 2nd IVF. She died the day after we heard the heartbeat for the first time, 10/8/14. I had our baby girl in May, 2015 and my life is now complete. Cant wait to show her the world! We took her to Vienna, Prague and Budapest in the summer of 2016 and we were in Venice and Milan for Christmas 2016. Our 3rd round of IVF in the fall of 2016 resulted in a pregnancy, but devastatingly, at 17 weeks pregnant I went for a ...
The names of major echocardiographic methods are listed below. Expand any abbreviations at first mention, unless otherwise indicated. The following commonly used echocardiographic indexes should also be expanded at first mention but are included here for reference: Terms are combined as in the following examples: IVSd IVSs LVIDd LVIDed LVIDes LVIDs LVPWd LVPWs RVIDd Ejection fraction is expressed as a percentage, eg, 60% (see also , Numbers and Percentages). |
Well, enough lurking....This site has provided me with some entertainment and information for awhile...its about time I let you know Im here. Im 41 years old and just received my 5 year all clear after a rough battle with Stage 3 rectal cancer. Had chemoradiation in NYC on the tumor before surgery....and had a complete response to that pre-surgical treatment. However, they still operate to make sure...no cancerous cells. All good news, especially for those of us who have rectal cancer (the response to chemoradiation, if complete, is a survival advantage). Anyway, it was not an easy battle. The radiation and chemotherapy together knocked me on my butt...I could not even run after awhile (I am a regular runner, former marathon runner). I perservered, with the help of my wife and young kids (except when they jumped on my staples). I do have some side effects from the surgery, especially related to using the bathroom much more frequently (like some of you here), but I manage, and am glad to be ...
The names of major echocardiographic methods are listed below. Expand any abbreviations at first mention, unless otherwise indicated. The following commonly used echocardiographic indexes should also be expanded at first mention but are included here for reference: Terms are combined as in the following examples: IVSd IVSs LVIDd LVIDed LVIDes LVIDs LVPWd LVPWs RVIDd Ejection fraction is expressed as a percentage, eg, 60% (see also , Numbers and Percentages). , Less ...
On Mar 26, 2013, at 5:22 PM, Sasha Pachev ,sasha at asksasha.com, wrote: , Regarding trying to pick a potential world-class marathoner from a 100 , meter sprint test. The idea is actually not as ridiculous as it , sounds. Most world-class marathoners will perform quite a bit better , than the average Joe in this test. Thus we expect at least 12.7 for , the guy to have a shot at making it. But we deal with some limitations , of the method. 12.7 is possible with bad biomechanics compensated by , raw fast-twitch power. A guy with a bad heart or some glycogen storage , problem might be able to make the cut, but when you start training him , for distance you realize that he has problems. He may not mentally , have what it takes to put in the training day after day even if his , physiology is there. , , When we look at a resume of a backend coder we need to realize that we , are trying to figure out how good of a marathon runner he might be by , having him run 100 meters. Resume writing is a different ...
Hello Sir, What is LV Global Hypokinesia? My mother got tested with 2D echo & colour Doppler test, The summary of the test is : LVIDD : 5.0 Cms LVIDS : 4.0 Cms LVEF : 30 % Left Atrium : 3.3...
Matthew King, 28, confounded everyones expectations - even his own - and forged a new life rich in incident, achievement and purpose after breaking his neck on the rugby pitch.
Directed by Graham Baker. With John Stamos, John Stockwell, Teri Polo, Sandy McPeak. The US Army recruits a delinquent biker to train their new motorcycle squad for an important mission.
Cardiomegaly, or an enlarged heart, can be caused by a birth defect or it can develop later in life. Treatment and outlook depend on the underlying cause.
Tom MacCormick is a former skinny kid who was told he was too small to make it as a rugby player. Since then, he has added over 40 pounds to his frame and helped hundreds of clients to build muscle and drop fat. Page 2
Purpose: The aim of the present study was to report the radiographical prevalence of overhanging fillings in a group of Swiss Army recruits in 2006 and to relate the dimensions of the overhangs to clinical parameters. Materials and Methods: A total of 626 Swiss Army recruits were examined for their periodontal conditions, prevalence of caries, and stomatological and functional aspects of the masticatory system and halitosis. In particular, the present report deals with the presence or the absence of fillings, the presence or the absence of overhangs and their relation to clinical and radiographic parameters. Results: A total of 16,198 interdental sites were evaluated on bitewing radiographs. Of these sites, 15,516 (95.8%) were sound and 682 (4.2%) were filled. Amalgam restorations were found in 94.1% and resin composite fillings in 5.9% of the sites. Of these 682 sites, 96 (14.1%) yielded overhanging margins of various sizes. This low prevalence of fillings represents not only a substantial ...
Shoes and Socks. Select the shoes-and the socks-youll wear in the marathon. The shoes should be relatively lightweight but provide good support, and the socks should be the type you wear in other races.. NYC has a lot of hills. If at all possible, start doing runs on the same topography as the marathon.. Drink and Drink Some More. Sports drinks and energy gels will fuel you during the race. Find out how often the marathon will have aid stations, and practice drinking at that rate.. Dress Comfortable. Run in real running clothes, and not a suffocating T-shirt.. Visualize success. Visualize yourself crossing the finish line as the clock shows a new personal best.. Stay Calm. Reduce the outside stresses in your life as much as possible the last week. ". Carb-load, dont fat-load. Concentrate on eating carbohydrate-rich foods, such as pasta, potatoes, bread, fruit and fruit juice, low-fat milk and yogurt, low-fat treats, and sports drinks. Its the carbs, after all, not fat or protein, that will ...
Many Americans today live in fear of Alzheimers, for that terrible disease seems able to steal our soul and obliterate our personality. But it does not. It only has the power to lock it up for a season, until the One who made it calls it back from its troubled slumber. The psyche does not die, but goes deep down into a place where neither moth nor rust can corrupt, where thieves cannot break in and steal.. Consider the marathon runner whose car veers off the road, leaving him paralyzed and confined to a wheelchair. Though his broken body prevents him for now from expressing the joy he takes in running, it does not have the power to annihilate that joy. His spirit remains that of a marathon runner, despite the condition of his legs.. Or consider the child born with Down syndrome or severe autism. Though the world often views such children as having no personality, those blessed teachers with the patience and compassion and eyes to see know differently. Such children do have a unique ...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
A baby boy was admitted to hospital with an injury typically seen in rugby players in the months before his death, a court heard.
A marathon is 26 miles 385 yards!. The marathon brings the runner deepest satisfaction and joy. Finishing, I always feel the excitement, not only from the fact that I, perhaps, had his best result, but from what has come true my intentions and I was on the track until the end.. My first marathon, which I ran at the age of 18 years (Boston, 1970), will forever remain in my memory. Then my goal was to participate in the race and go the distance at least to the center Prodehl. After the start I felt well prepared and able to overcome all the distance to the finish line. But, despite the confidence still felt restless curiosity.. The beginning, as I thought, was very easy, but time dragged slowly. After the Heartbreak hill behind us, I felt the need to run faster because the last 5 miles of road is a fairly steep descent. And then I had a "barrier" - the danger that lies in wait for any marathon runner. From that moment begins Continue reading →. ...
An enlarged heart, or cardiomegaly, is a symptom of another medical condition it is not a. Physicians at the Mayo Clinic advise that patients with cardiomegaly get modest exercise, after. How to Reduce Estrogen in Men Through the Diet. Adherence to an appropriate diet and regular exercise. Diet should. Cardiomegaly. A nine pound weight loss was re-. vascular markings, and normal exercise tol erance without stridor. The patient. ale due to airway obstruction but without.
The first marathon is said to have taken place in 776 B.C., where the very first event of the first-ever Olympic games was a foot race. The first notable marathon runner was a Greek soldier named Pheidippides, who is said to have run from Marathon to Athens to deliver the news of a military victory against the Persia
A marathon runner collapses after running on a hot day. Although the runner consumed water along the route, analysis shows that many of the runners red blood cells had burst. Why did the red blood cells burst? (Hint: On hot days many runners consume drinks that contain sugar, salt and water.) ...
DR. PAUL D. THOMPSON, a 60-year-old marathon runner and chief of cardiology at Hartford Hospital, stood in front of a medical audience recently and began his talk with a story about himself.. "Ive been lifting weights since I was 12 years old and look at me," he said. Dr. Thompson is small and wiry with not a bulging muscle on him. He speculated that he must have a genetic inability to build muscles, no matter how hard he works at it.. But are his muscles healthy? It is not the kind of question most people ask themselves. But muscle researchers say it is important because muscle health is emerging as an important part of overall health. And, they say, when it comes to muscles, bulk does not matter. How big they can become depends on your sex as well as genetics. What matters for health is whether, like Dr. Thompson, you use them.. Healthy muscles, researchers say, are those that have been worked, stressed and pushed to their limit so that they have enough power and strength to get you through ...
What killed Ranjan Das and Lessons for Corporate India A month ago, many of us heard about the sad demise of Ranjan Das from Bandra, Mumbai. Ranjan, just 42 years of age, was the CEO of SAP-Indian Subcontinent, the youngest CEO of an MNC in India. He was very active in sports, was a fitness freak and a marathon runner. It was common to see him run on Bandras Carter Road. Just after Diwali, on 21st Oct, he returned home from his gym after a workout, collapsed with a massive heart attack and
What killed Ranjan Das and Lessons for Corporate India A month ago, many of us heard about the sad demise of Ranjan Das from Bandra, Mumbai. Ranjan, just 42 years of age, was the CEO of SAP-Indian Subcontinent, the youngest CEO of an MNC in India. He was very active in sports, was a fitness freak and a marathon runner. It was common to see him run on Bandras Carter Road. Just after Diwali, on 21st Oct, he returned home from his gym after a workout, collapsed with a massive heart attack and
Hi, Im John. Im a Christ Follower. Technology Expert. Bicycle Rider. 1/2 Marathon Runner. Paleo-esque. Social Media Junkie. Columbus Townie.
Caffeine shown to increase performance in rugby players A new study into the effects of caffeine on rugby players suggests it can significantly enhance performance in several ways.
If Danish army recruits want to smoke a cigarette, their commanders humiliate them while they do so, reports Metroexpress. Some have been told to climb trees or stand on one leg, while others have been forced to stand in a puddle or lie down with their ...
Regional variation in sweating over the body is widely recognised. However, most studies only measured a limited number of regions, with the use of differing thermal states across studies making a goo
A captivating name for a woman of class, style, and elegance. Though there have been several male athletes named Dominique, its a hard one for a regular guy to pull off.. ...
OBJECTIVES: We tested the hypothesis that the attenuated heart rate (HR) response to sympathetic activation following swim training in the guinea pig (Cavia porcellus) results from a peripheral modulation of pacemaking by nitric oxide (NO). METHODS: Nitric oxide synthase (NOS) inhibition on the increase in heart rate with sympathetic nerve stimulation (SNS) was investigated in the isolated guinea pig double atrial/right stellate ganglion preparation from exercise trained (6-weeks swimming, n=20) and sedentary animals (n=20). Western blot analysis for neuronal nitric oxide synthase (nNOS) was performed on the stellate ganglion from both groups. RESULTS: Relative to the control group, the exercise group demonstrated typical exercise adaptations of increased ventricular weight/body weight ratio, enhanced skeletal muscle citrate synthase activity and higher concentrations of [3H]ouabain binding sites in both skeletal and cardiac tissue (P|0.05). The increase in heart rate (bpm) with SNS significantly
inproceedings{3036208, abstract = {Aims: Significant aortic regurgitation (AR) may cause left ventricular (LV) dilatation and heart failure. The aim was to quantify LV function in AR horses by tissue Doppler imaging (TDI) and two-dimensional speckle tracking (2DST). Methods: Echocardiographic examinations were performed on ten healthy horses (10{\textpm}4 years;509{\textpm}58 kg) and fourteen horses with significant AR (17{\textpm}4 years;497{\textpm}93 kg). By 2DST, global radial (SR) and longitudinal (SL) strain were measured. Regional systolic radial displacement (DRS) by 2DST and velocity (VS) by TDI were measured in the interventricular septum and LV free wall. LV end-diastolic internal diameter (LVIDd) and fractional shortening (FS) were measured from a short-axis M-mode at chordal level. Results: Seven horses showed moderate AR (LVIDd range 11.0-12.7 cm), seven severe AR (LVIDd 13.3-16.9 cm). FS, SR and SL showed no significant differences. However, SL was significantly correlated with ...
In most models of pathological hypertrophy studied to date, inhibition of calcineurin-NFAT signaling has yielded either a reduction in the hypertrophic response and/or a delay in the progression from hypertrophy to heart failure.9,38 The data presented in this study extend this paradigm to demonstrate that calcineurin-NFAT signaling is activated in a sustained manner during both TAC-induced pressure overload and myocardial infarction-induced heart failure. However, very little is presently known regarding the role of calcineurin-NFAT signaling in regulating physiological hypertrophy or adaptive growth of the myocardium. Our results indicate that calcineurin-NFAT is not activated after either voluntary wheel-running or swimming, despite the observation of significant cardiac hypertrophy. In fact, swimming exercise even produced a significant and reproducible reduction in NFAT-luciferase activity in the heart at certain time points. Also of note, direct infusion of GH-IGF-1, which is thought to ...
Cardiomegaly is a medical condition in which the heart is enlarged. It is more commonly referred to as an enlarged heart. The causes of cardiomegaly may vary. Many times this condition results from high blood pressure (hypertension) or coronary artery disease. An enlarged heart may not pump blood effectively, resulting in congestive heart failure. Cardiomegaly may improve over time, but many people with an enlarged heart need lifelong treatment with medications. Having an immediate family member who has or had cardiomegaly may indicate that a person is more susceptible to getting this condition. Cardiomegaly is not a disease but rather a condition that can result from a host of other diseases such as obesity or coronary artery disease. Recent studies suggest that cardiomegaly is associated with a higher risk of sudden cardiac death (SCD). Cardiomegaly is a condition affecting the cardiovascular system, specifically the heart. This condition is strongly associated with congestive heart failure. ...
1044. HISTORY: Patient is a 51 year old female who presented complaining of a 15 pound weight gain over the past year despite beginning a strenuous triathlon and marathon training program. Patient was training up to 2 hours per day 5-6 days per week. Careful 3-day diet analysis estimated daily caloric intake at 1000-1200 calories per day. Patient denies any new medications although she had been taking prescription medication for depression for several years. Patient complained of irregular menses but denied amenorrhea. She denied any change in her eating habits during the period of the weight gain. Patient also denied fatigue, constipation, dry skin, hair loss, cold intolerance or change in her voice. Patient reports no family history of thyroid disease or diabetes. She also denied any polyuria, polydypsia or hyperphagia.. PHYSICAL EXAMINATION: Examination revealed a well-developed, wellnourished slightly overweight female. Body fat was measured at 37 % via bioelectrical impedance. There was no ...
Another study done on gout confirms that sugar intake, especially fructose, can be a major contributing factor in gout symptoms.. In a study of 51,529 professional males, a study of dietary habits monitored the possibilities of what could cause gout in men from ages of 40 to 75 years old during the years of 1986 to 1998. Only 49,166 participants mailed in their evaluations the first year of the study.. These men were given evaluation sheets to turn in of what they ate and didnt eat by marking pre-assigned amounts on the sheets. They were dentists, optometrists, veterinarians, osteopaths, and pharmacists.. The study also accounted for the effects on any exercise, medication, or medical conditions that the participants might have had prior to starting the study. This also studied any changes in the participants exercise, medication, or developments of medical conditions during the study.. Along with keeping up with the BMI in the participants over the years. During this study, there were 755 ...
The pooled estimate from two studies was that stretching decreased the risk of injury by 5%. This effect was statistically non-significant. Even if this effect was not simply a sampling error it would not be large enough to be of practical significance. In army recruits, whose risk of injury in the control condition is high (approximately 20% over the training period of 12 weeks), a 5% reduction in relative risk implies a reduction in absolute risk of about 1%. Thus, on average, about 100 people stretch for 12 weeks to prevent one injury and (if the hazard reduction was constant) the average subject would need to stretch for 23 years to prevent one injury.21 Most athletes are exposed to lower risks of injury so the absolute risk reduction for most athletes is likely to be smaller still. 29 30. Although these data imply that the muscle stretching protocol used in these studies does not appreciably reduce risk of injury in army recruits undergoing military training, it is not possible to rule out ...
Our intention is to use pacemakers for the course to aid inexperienced participants use this as the ideal marathon preparation event.. Pacers will be running at approx 105% of the 3.00, 3.30, 4.00 and 4.30 Hour MARATHON Pace.. Were pacing 5% slower than your marathon pace to make sure you dont empty the tank on this event which should be treated as preparation race for DCM.. Pacing will be based on the following:. - 3:00 Marathon Pace Group: Planned 2:22 for 3/4 Marathon = approx. 4′ 28″ /km = approx. 7′ 13″ /mile. - 3:30 Marathon Pace Group: Planned 2:45 for 3/4 Marathon = approx. 5′ 13″ /km = approx. 8′ 24″ /mile. - 4:00 Marathon Pace Group: Planned 3:10 for 3/4 Marathon = approx. 6′ /km = approx. 9′ 40″ /mile. - 4:30 Marathon Pace Group: Planned 3:43 for 3/4 Marathon = approx. 6′ 44″ /km = approx. 10′ 50″ /mile. Please identify and join an appropriate pacing group at the race briefing at Race HQ at 9.40am. ...
Question - Doctor, I am a 23 year old male athlete who works out alot - I2. Find the answer to this and other Cardiology questions on JustAnswer
Background: Recent studies have shown a substantial decline in caries experience in Australian Army recruits between 1996 and 2002-2003, and in Australian adults between 1987-1988 and 2004-2006. However, studies in children have reported an increasing trend in caries experience between 1998 and 2002. The aim of this study was to investigate caries experience in Australian Army recruits in 2008 ...
2018 Elsevier Ltd Background: In people with moderate-to-severe chronic obstructive pulmonary disease (COPD), the minimal detectable difference (MDD) in endurance shuttle walk test (ESWT) performance following exercise training is unclear. We sought to determine the MDD for ESWT performance following supervised ground-based walking training using anchor- and distribution-based approaches and report whether these values exceeded random variation in test performance. Methods: Participants with COPD trained for 30-45 min, 2-3 times weekly for 8-10 weeks. The ESWT was performed before and after the training period. Immediately after training, participants rated their change in walking ability using a Global Rating of Change scale. Receiver Operating Characteristic curves were used to derive the value that best separated those who perceived their improvement in walking ability to be at least a little better from almost the same, hardly any change. These values were compared with those calculated ...
Q: What is your name?. My name is Antoine Tanne.. Q: Where are you from?. I am French and I come from a little city in Normandy really close to D-Day beach.. Q: What is your role at Massachusetts General Hospital?. I am a researcher in the Mass General pediatrics department. My research work aims at better understanding innate immunity in infectious diseases and more precisely upon viral and bacterial co-infection.. Q: Why did you choose to run the marathon for MassGeneral Hospital for Children?. In 2010, I was standing by the finish line of the Boston Marathon for the first time. After having seen so many charity runners, I went back home and I read more about the Mass General charity run program created by Dr. Howard Weinstein. After this, there was no doubt that I had to run the Boston Marathon as a member of this team. Running against cancer is for me a way to support my relatives (my aunt and my godfather) and all people who fight against those diseases. Running for children is also a way ...
Figure 1. Cardiac hypertrophy in a patient with Fabry disease. A. and B. Concentric LV hypertrophy. Note the presence of a hyperechogenic region in the posterior wall (mid-wall level, arrow), corresponding to localized fibrosis. C. Right ventricular free wall hypertrophy from subcostal view.. In most cases of FD, the LVH is concentric and non-obstructive; however, an asymmetrical hypertrophy with septal thickening and posterior wall fibrotic thinning may present in advanced cases. There have also been rare case reports of patients with obstructive forms of hypertrophic cardiomyopathy. The LVH is progressive in nature, and is rarely severe in children or adolescents. Of note, the echocardiographically derived cardiac mass is proportional to the electrocardiographic LVH low-voltage on the ECG, presenting an argument against Fabry disease in these patients.. Right ventricular (RV) hypertrophy is also common [9] (around 70% of Fabry patients display it) and may progress to RV dilation (Figure 1C). ...
... (AHS), also known as athlete's heart, athletic bradycardia, or exercise-induced cardiomegaly is a non- ... The two types of exercise are static (strength-training) and dynamic (endurance-training). Static exercise consists of weight ... This type of exercise also increases both heart rate and stroke volume of the heart. Both static and dynamic exercises involve ... Cardiomegaly is the state of an enlarged heart, and cardiac hypertrophy the thickening of the muscular wall of the heart, ...
It is not uncommon to undergo cardiopulmonary exercise testing (CPET), which measures the heart's response to exercise, to ... it is believed that the eccentric hypertrophy is induced by volume-overload and that the concentric hypertrophy is induced by ... Athletic heart syndrome Cardiac fibrosis Cardiology Cardiomegaly Cardiovascular disease Right ventricular hypertrophy ECG See ... It is a response to 'volume-overload', either as a result of increased blood return to the heart during exercise, or a response ...
"Physical activity guidelines for adults". NHS Choices. Archived from the original on 2017-02-19. "Exercise‐based cardiac ... Mental stress-induced myocardial ischemia is associated with an increased risk of heart problems in those with previous heart ... Inflammatory cardiomegaly Myocarditis - inflammation of the myocardium, the muscular part of the heart. Valvular heart disease ... At least 150 minutes (2 hours and 30 minutes) of moderate exercise per week. Exercise-based cardiac rehabilitation reduces risk ...
This is the basis for the so-called fight-or-flight response, but such stimulation can also be induced by stimulants such as ... from healthy response to exercise or from cardiac arrhythmia), and that tachyarrhythmia be reserved for the pathologic form ( ... such as with exercise) or abnormal (such as with electrical problems within the heart). ...
Medications and exercise are roughly equally effective.[64] High levels of physical activity reduce the risk of coronary artery ... Chronic high-grade narrowing of the coronary arteries can induce transient ischemia which leads to the induction of a ... Exercise; aerobic exercise, like walking, jogging, or swimming, can reduce the risk of mortality from coronary artery disease.[ ... Exercise and physical activity in the prevention and treatment of atherosclerotic cardiovascular disease. Major Recommendations ...
By contrast, the exercise induced dyspnoea and orthopnoea progressed to the point where his capacity to perform activities of ... GE: Chest radiograph was normal with no cardiomegaly and normal lung fields. Spirometry was normal (forced expiratory volume in ... His chest X-ray now showed cardiomegaly, blunted costophrenic angles and bilateral lower zone infiltrates. A further ... peripheral oedema and a reduction in exercise tolerance to approximately 10 m walking. Upper gastrointestinal endoscopy was ...
5) Exercise-induced ischemia or ventricular arrhythmias observed by radionuclide stress test during an evaluation reaching at ... Cardiomegaly (enlarged heart; heart weighed 660 grams [g]; predicted normal weight is 463 g [ranges between 351 g and 611 g as ... Health and Wellness Programs. The FD does not have a wellness/fitness program, and no exercise equipment is available in the ... 4) Maximal exercise tolerance of , 42 milliliters of oxygen per minute per kilogram or , 12 metabolic equivalents (METs) ...
Feld H, Guadanino V, Hollander G, Greengart A, Lichstein E, Shani J [1991]. Exercise-induced ventricular tachycardia in ... Left ventricular hypertrophy and cardiomegaly are both associated with an increased risk of sudden cardiac death.2, 37-39 ... Provide exercise equipment in all fire stations. * Ensure that all members participate in the Fire Departments mandatory ... Exercise (strength and aerobic) equipment is located in 24 of the 30 fire stations. Fire fighters also have access to the City ...
... decreased exercise capacity and shortness of breath during exercise ■ ECG: low voltage of QRS complexes and P and T waves ■ CXR ... Clinical Manifestations of Hypothyroidism -- Cardiovascular System ■ Myxedema induces coronary artery disease ?? ■ CAD more ... cardiomegaly  interstitial edema, myofibrillary swelling, LV dilatation, pericardial effusion * 11. ... and decreased exercise capacity  impaired respiratory function + cardiovascular disease ■ Hypoventilation (shallow and slow ...
However, his exercise tolerance was well. Any dyspnea on effort had not seen during out-patient clinic (NYHA I). Ventilation/ ... A chest radiograph revealed marked cardiomegaly and mediastinum expansion without a difference of increased radiolucency ... Hemodynamic collapse induced by general anesthesia in a patient with an unruptured thoracic aortic aneurysm: a case report. ... Two cases of TAA-induced severe hypoxia with compression of the left main bronchus and right pulmonary artery have been ...
Athletic heart syndrome (AHS), also known as athletes heart, athletic bradycardia, or exercise-induced cardiomegaly is a non- ... The two types of exercise are static (strength-training) and dynamic (endurance-training). Static exercise consists of weight ... This type of exercise also increases both heart rate and stroke volume of the heart. Both static and dynamic exercises involve ... Cardiomegaly is the state of an enlarged heart, and cardiac hypertrophy the thickening of the muscular wall of the heart, ...
We are hoping its athletes heart [athletic bradycardia, or exercise-induced cardiomegaly] and VTAC, after years of pushing so ...
Cardiomegaly, Exercise-Induced, Cardiomyopathies, Coronary Vessels, Death, Sudden, Cardiac, Echocardiography, ... Clinical Topics: Arrhythmias and Clinical EP, Heart Failure and Cardiomyopathies, Noninvasive Imaging, Sports and Exercise ... Consensus Statement of the Study Group of Sport Cardiology of the Working Group of Cardiac Rehabilitation and Exercise ... Ethnic differences in physiological cardiac adaptation to intense physical exercise in highly trained female athletes. ...
Exercise capacity, lung congestion, maximal oxygen consumption, arterial oxygen saturation, and survivorship were all improved ... Results: At 100 days post-TAC, untreated KATP channel-deficient hearts developed cardiomegaly, regional and global left ... Abstract 12573: Induced Pluripotent Stem Cells Treatment Prevent Heart Failure and Ventricular Dyssynchrony in Genetic Non- ... Abstract 12573: Induced Pluripotent Stem Cells Treatment Prevent Heart Failure and Ventricular Dyssynchrony in Genetic Non- ...
... thereby inducing hypothermia, thus benefiting patients suffering from illnesses characterized by tissue anoxia. ... Cardiomegaly is a medical condition wherein the heart is enlarged. It can often be associated with other serious medical ... lack of exercise and increasing average lifespan. The main causes of death and disability among cardiovascular diseases are ... WO2009071097A1 - Use of hypothermia inducing drugs - Google Patents. Use of hypothermia inducing drugs Download PDF Info. ...
Also known as athletic bradycardia, or exercise-induced cardiomegaly, Athletes heart is generally considered benign, but may ... Activity data from wearables may help us identify individuals more likely to have this condition due to exercise, and are ... "An enlarged left ventricle could be caused by heart disease or harmless adaptation to sustained exercise, and these two ...
Moreover, the exercise induced diastolic dysfunction may persist despite cessation of exercise. Kono et al reported that the ... 1963) Value of prolonged bed rest in management of cardiomegaly. JAMA 183:81-87. ... 1993) Effect of heart failure on the mechanism of exercise-induced augmentation of mitral valve flow. Circ Res 72:795-806. ... Conclusions Exercise induced diastolic left ventricular dysfunction of the failing heart persists for 24 hours or more after ...
keywords = "blood pressure, cardiomegaly, exercise-induced, exercise, hypertension, hypertrophy, left ventricular",. author = " ...
1 Cardiomegaly, Exercise-Induced. *1 Congenital heart defects. *1 Congenital heart disease ... No Synergic Effect of Sildenafil Administration on Exercise Capacity Improvement in a Fontan Patient with Regular Exercise ... Kindergarten Children with Congenital Heart Disease Show Good Physical Activity but Reduced Motor Skills in Comparison with ...
1 Cardiomegaly, Exercise-Induced. *1 exercise. *1 Heart Ventricles --anatomy & hist.... *1 Heart Ventricles --physiopathology ...
Cardiomegaly, Exercise-Induced / physiology Actions. * Search in PubMed * Search in MeSH * Add to Search ... The athletes ECG and the exercise related sudden cardiac death]. Trachsel LD, Wilhelm M. Trachsel LD, et al. Ther Umsch. 2015 ...
Exercise-Induced/genetics , Cardiomegaly/genetics , Exercise/physiology , MicroRNAs/physiology , Cardiomegaly, Exercise-Induced ... Animals , Male , Rats , Cardiomegaly, Exercise-Induced/drug effects , Cardiomegaly, Exercise-Induced/physiology , Heart/drug ... Humans , Atrial Fibrillation/etiology , Cardiomegaly, Exercise-Induced , Atrial Fibrillation/diagnosis , Cardiomegaly, Exercise ... There is no fibrosis and no cardiac dysfunction in eccentric or concentric hypertrophy induced by exercise training. Therefore ...
Cardiomegaly (Heart Hypertrophy) 10/15/1987 - "Lactate dehydrogenase activity increased significantly (P less than 0.01) in ... These data indicate that (1) beta-adrenergic blockade prevents training-induced cardiac hypertrophy; (2) beta-antagonists have ... myocardium may increase its ability to utilize lactate during exercise with training despite beta 1-blockade.". ...
Animals , Male , Rats , Cardiomegaly, Exercise-Induced/drug effects , Cardiomegaly, Exercise-Induced/physiology , Heart/drug ... Full text: Available Index: LILACS (Americas) Main subject: Physical Conditioning, Animal / Thyroxine / Cardiomegaly, Exercise- ... Assess hypertrophic response of the association of thyroid hormone and exercise in the rat heart. Methods:. We used 37 Wistar ... Induced / Heart Clinical aspect: Diagnosis Limits: Animals Language: Portuguese Journal: Arq. bras. cardiol Journal subject: ...
Sex differences in morphological and functional aspects of exercise-induced cardiac hypertrophy in a rat model. Oláh, A., ... Characterization of the dynamic changes in left ventricular morphology and function induced by exercise training and detraining ... Relationship between Cardiac Remodeling and Exercise Capacity in Elite Athletes: Incremental Value of Left Atrial Morphology ... sensitivity correlates with left ventricular contractility during the progression of pressure overload-induced left ventricular ...
Cardiomegaly, Exercise-Induced. *Hemodynamics. *Myocardial Contraction. *Neovascularization, Physiologic. *Ventricular Function ... Right ventriculo-arterial uncoupling and impaired contractile reserve in obese patients with unexplained exercise intolerance. ...
Cardiomegaly, Exercise-Induced. *Hemodynamics. *Myocardial Contraction. *Neovascularization, Physiologic. *Ventricular Function ... Association between lung ultrasound findings and invasive exercise haemodynamics in patients with undifferentiated dyspnoea. ...
... in marathoners with exercise induced hypertension compared to normotensive controls before and after running a marathon. ". 02/ ... Cardiomegaly (Heart Hypertrophy) 04/01/1996 - "These data suggest that blocking the action of endothelin-1 with a receptor ... 06/01/2013 - "Based on these studies, drugs that increase NO bioavailability, attenuate endothelin-1 induced pulmonary ... 01/2010 - "The purpose of this study was to determine the role of endothelin 1 in mediating sFlt-1-induced hypertension in ...
Increased sympathetic discharge may induce sinus tachycardia. Is there a cardiac history? ... Cardiomegaly. Congestive heart failure or cardiomyopathy. Holter monitor or event recorder. Capture aberrant rhythm, frequency ... Graded exercise test. Preexcitation or aberrant rhythm. Type of tachyarrhythmia. Echocardiography. Structural or valvular ...
... exercise capacity, blood pressure response, and ventilation efficiency. They are also useful to assess exercise-induced ... Those with minimal TR and mild cardiomegaly usually do not need surgery and lead normal lives. Patients with ASD or PFO are at ... Low-to-medium intensity physical activity is encouraged. Physical activity in patients with a history of arrhythmias should be ... or aortic root dilation should avoid isometric exercise and should limit exercise to low-intensity activities or sports. The ...
  • However, although acute cardiovascular changes induced during BHD and fatal complicaitons by extreme diving have been studied, the long-term effects of shallow but frequent intermittent apnea by repetitive BHD have not been well studied. (biomedcentral.com)
  • However, a subset o rcvs patients initially and again elt good or acute respiratory decompensation and cardiomegaly. (roanokechowan.edu)
  • In patients with acute gout attack such as ranitidine or symptomatic treatment drugs as de ned as paralysis o en accompanied by urgency, bloating, and flatulence malaise, anorexia, and constipation. (roanokechowan.edu)
  • After intravenous anesthesia, his aneurysm occluded the left main bronchus and right pulmonary artery simultaneously, and induced severe hypoxia. (springer.com)
  • Apnea, whether voluntary or involuntary, induces several physiological changes, which are a type of protective responses to hypoxia and involve potential health hazards as well. (biomedcentral.com)
  • Obstructive sleep apnea (OSA) is a condition in which breathing stops involuntarily for a short time during sleep, has something in common with BHD in terms of the repeated exposure to intermittent apnea-induced hypoxia, even though it's pathophysiology is different from what of BHD. (biomedcentral.com)
  • A wide pulse pressure will provide the most common surgical procedure for dissociative sedation a trancelike cataleptic state induced by airway manipulation, hypoxia, and sensory testing, and resistance to lengthening as the musculoskeletal component, an assessment for children with human immunodeciency virus hiv and hepatitis b surface antigen, hepatitis c are not indicated in treatment of cervical lordosis, adequate intervertebral disc between l and below the discriminatory zone with an api. (centerforalexandriaschildren.org)
  • Derived by nuclear reprogramming of somatic tissue, induced pluripotent stem (iPS) cells repair ischemic heart injury. (ahajournals.org)
  • The present invention relates to the induction of hypothermia in humans in a predictable and dose responsive fashion by use of a pharmaceutical composition comprising a neurotensin or a neurotensin analog or a synthetic neurotensin or a neurotensin receptor agonist, thereby inducing hypothermia, thus benefiting patients suffering from illnesses characterized by tissue anoxia. (google.com)
  • It contains two selenocysteine groups per molecule and is a major component of a redox system with a multiplicity of functions, among which is the capacity to degrade locally excessive and potentially toxic concentrations of peroxide and hydroperoxides likely to induce cell death and tissue atrophy ( 6 ). (fao.org)
  • There is no evidence that COQ10 improves life expectancy or is able to induce fat loss or muscle tissue growth, even though it is present in mitochondria. (examine.com)
  • By contrast, the exercise induced dyspnoea and orthopnoea progressed to the point where his capacity to perform activities of daily living was impaired. (bmj.com)
  • Platz E, Merz A, Silverman M, Lewis E, Groarke JD, Waxman A, Systrom D. Association between lung ultrasound findings and invasive exercise haemodynamics in patients with undifferentiated dyspnoea. (harvard.edu)
  • The AngII-induced reduction in muscle mitochondria in mice was partially, but significantly, reversed by blockade of either AT1R or AT2R, associated with increased fat oxidation, decreased muscle triglyceride, and improved glucose tolerance. (diabetesjournals.org)
  • Phosphofructokinase (PFK) Deficiency: Autosomal recessive disorder causing chronic hemolysis and hemolytic crises, especially with exercise. (animalia-life.club)
  • The hair is therefore rec- can induce hemolytic anemias. (wellchild.org)
  • Exercise-induced bronchospasmexercise-induced bronchospasm should be observed in all patients after they have limited ventilatory reserve, may have severe thyrotoxicosis and cns complications, with subsequent necrosis and glomerulonephritis account for of congenital rubella infection during heterosexual intercourse because of a stone. (iahf.com)
  • It is noteworthy that cardiomegaly is developed by different diseases, including valvular heart diseases, IHD, and cardiomyopathy as well as pericardial diseases. (ircmj.com)
  • There is general consensus that HFpEF patients have increased left ventricular filling pressures (LVDP) and relatively normal systolic function at rest5,8,10, but two critical questions remain: what causes the increase in LVDP, and, are there important deficits in the cardiovascular response to exercise stress in HFpEF patients3,4? (strokecenter.org)
  • In addition, the large areas of adrenergic denervation in the myocardium decrease the contractile reserve: an abnormal response to exercise in the presence of normal basal systolic function is a sign of incipient diabetic cardiomyopathy. (stylesstar.com)
  • Glycogen metabolism: Aerobic exercise is essential for intermittent or submaximal contraction. (medscape.com)
  • Intense exercise produces earlier HGH secretion, endurance exercise produces HGH peaks in mid-term, while intermittent intense exercise is claimed to result in the highest HGH levels. (xroids.to)
  • 4-6 Moreover, exercise training may in itself have deleterious effects on the failing myocardium, because of the presence of several intrinsic abnormalities susceptible to exercise induced sympathetic stimulation and consequent tachycardia. (bmj.com)
  • Phosgene-induced leakage of fluid from capillaries into the pulmonary interstitium is normally opposed by lymphatic drainage from the parenchyma, but as the fluid leakage increases, normal drainage mechanisms become progressively overwhelmed. (fas.org)
  • Lipid metabolism: Lipid is an important source of energy in sustained submaximal exercise (ie, exercise lasting longer than 40 min). (medscape.com)
  • Results The intensity of exercise, as assessed by respiratory gas analysis, was lower in patients with dilated cardiomyopathy than in normal subjects. (bmj.com)
  • A chest radiograph revealed marked cardiomegaly and mediastinum expansion without a difference of increased radiolucency between the left and right lungs. (springer.com)
  • An enlarged left ventricle could be caused by heart disease or harmless adaptation to sustained exercise, and these two conditions share overlapping features. (sciblogs.co.nz)
  • However, as dilatation progresses, left ventricular ejection fraction and stroke volume deteriorate during exercise and at rest, and finally pulmonary capillary wedge pressure increases and patients become symptomatic 1.5-3 years after the infarct. (ox.ac.uk)
  • The death certificate and the autopsy, completed by the County Medical Examiner, listed "complications of atherosclerotic cardiovascular disease" as the immediate cause of death with "cardiomegaly" as a significant condition. (cdc.gov)
  • This stimulation of muscle protein synthesis and growth is qualitatively different to that induced by work, since insulin is required for HGH-stimulated muscle growth but not for that induced by work. (xroids.to)
  • The neuroprotective efficacy of induced hypothermia following or during ischemia of the brain is evident in experimental animal models of stroke [1 -1 (google.com)
  • The efficacy of exercise training on a daily basis in dilated cardiomyopathy requires further evaluation. (bmj.com)
  • Design and patients Transmitral flow velocity profiles and standard non-invasive haemodynamic indices were obtained serially over seven days after symptom limited bicycle exercise tests in 18 patients with dilated cardiomyopathy and eight normal subjects. (bmj.com)
  • Enlarged heart (cardiomegaly) isn't a disease, but rather a symptom of another condition. (lynchspharmacy.com)
  • however, presence or absence of cardiomegaly in CXR depends on the interpreter's judgment ( 1 ). (ircmj.com)
  • In three patients with cardiomyopathy we also measured the pulmonary capillary wedge pressure for 24 hours after exercise. (bmj.com)