The restoration of the sequential order of contraction and relaxation of the HEART ATRIA and HEART VENTRICLES by atrio-biventricular pacing.
Types of artificial pacemakers with implantable leads to be placed at multiple intracardial sites. They are used to treat various cardiac conduction disturbances which interfere with the timing of contraction of the ventricles. They may or may not include defibrillating electrodes (IMPLANTABLE DEFIBRILLATORS) as well.
Regulation of the rate of contraction of the heart muscles by an artificial pacemaker.
A device designed to stimulate, by electric impulses, contraction of the heart muscles. It may be temporary (external) or permanent (internal or internal-external).
A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
Implantable devices which continuously monitor the electrical activity of the heart and automatically detect and terminate ventricular tachycardia (TACHYCARDIA, VENTRICULAR) and VENTRICULAR FIBRILLATION. They consist of an impulse generator, batteries, and electrodes.
A form of heart block in which the electrical stimulation of HEART VENTRICLES is interrupted at either one of the branches of BUNDLE OF HIS thus preventing the simultaneous depolarization of the two ventricles.
A short vein that collects about two thirds of the venous blood from the MYOCARDIUM and drains into the RIGHT ATRIUM. Coronary sinus, normally located between the LEFT ATRIUM and LEFT VENTRICLE on the posterior surface of the heart, can serve as an anatomical reference for cardiac procedures.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
Surgical insertion of a prosthesis.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.
An impulse-conducting system composed of modified cardiac muscle, having the power of spontaneous rhythmicity and conduction more highly developed than the rest of the heart.
Impaired impulse conduction from HEART ATRIA to HEART VENTRICLES. AV block can mean delayed or completely blocked impulse conduction.
A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.
A publication issued at stated, more or less regular, intervals.
Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.
Organized services in a hospital which provide medical care on an outpatient basis.
The omission of atrial activation that is caused by transient cessation of impulse generation at the SINOATRIAL NODE. It is characterized by a prolonged pause without P wave in an ELECTROCARDIOGRAM. Sinus arrest has been associated with sleep apnea (REM SLEEP-RELATED SINUS ARREST).

Cardiac resynchronization therapy with and without implantable cardioverter-defibrillator. (1/472)

Cardiac resynchronization therapy (CRT) is recommended to reduce morbidity and mortality in patients with New York Heart Association class III/IV, who are symptomatic despite optimal medical therapy, and who had a reduced left ventricle (LV) ejection fraction and electrical dyssynchrony. The effects of CRT are reflected mainly by the degree and location of dyssynchrony and by working in insertion of optimal LV lead site. Echocardiography and Doppler echocardiography are considered to be good tools to measure LV dyssynchrony directly. However, the large randomized trials have shown that no single echocardiographic measure of dyssynchrony is recommended to improve patient selection for CRT beyond current guidelines. There were several unsolved issues on CRT, such as patient selection, electrical or electromechanical dyssynchrony criteria to patients for CRT, indication of patients with a narrow or slightly prolonged QRS width, indication of patients with atrial fibrillation, and indication of patients with mild heart failure or asymptomatic LV dysfunction, and device selection; CRT alone (CRT-P) or CRT in combination with implantable cardioverter therapy (CRT-D). This review paper summarized the concept of therapy, the current evidence regarding the indications, effectiveness and safety of CRT-P and CRT-D in patients with LV dysfunction, and unsolved issues.  (+info)

Prevalence and risk factors related to infections of cardiac resynchronization therapy devices. (2/472)

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Resumption of sinus rhythm in patients with heart failure and permanent atrial fibrillation undergoing cardiac resynchronization therapy: a longitudinal observational study. (3/472)

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Upgrading to resynchronization therapy after chronic right ventricular pacing improves left ventricular remodelling. (4/472)

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Effectiveness of cardiac resynchronization therapy in mild congestive heart failure: systematic review and meta-analysis of randomized trials. (5/472)

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Clinical and echocardiographic correlates of improvement in left ventricular diastolic function after cardiac resynchronization therapy. (6/472)

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Impact of reduction in early- and late-systolic functional mitral regurgitation on reverse remodelling after cardiac resynchronization therapy. (7/472)

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Optimization of myocardial strain imaging and speckle tracking for resynchronization after congenital heart surgery in children. (8/472)

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In recent decades, the prevalence of heart failure has steadily increased and can be considered a contemporary cardiovascular epidemic. Therefore, treatment of heart failure is a primary focus of cardiovascular disease management strategies. Cardiac resynchronization therapy: an established pacing therapy for heart failure and mechanical dyssynchrony provides basic knowledge about congestive heart failure and also covers the evolution of cardiac resynchronization therapy. State-of-the-art information and future directions of this therapeutic tool are explained. As cardiac resynchronization therapy (CRT) is a new therapy which still undergoes rapid advancement, it is imperative to provide updates on key issues. These include technological advances, the unique role of imaging to assess mechanical dyssynchrony, troubleshooting, recent key clinical trials, and the incorporation of monitoring capabilities into CRT or CRT plus defibrillation devices. Cardiac resynchronization therapy is an exciting ...
Cardiac Resynchronization Therapy (CRT) has emerged as a promising therapeutic addition in patients with drug refractory heart failure (HF). Along with providing relief of symptoms of HF, cardiac resynchronization therapy defibrillators (CRT-D) are used for the prevention of sudden cardiac death (SCD). Although there are concerns that the defibrillation threshold (DFT) estimates are elevated in the heart failure (HF) patient population due to lower LV ejection fraction (EF) and left ventricular (LV) dysfunction, there is paucity of data available to evaluate this theory.. Recently, two different studies in a retrospective manner evaluated the energy requirements in patients receiving cardiac resynchronization therapy defibrillators (CRT-D). Burke et al analyzed DFTs in 50 patients each implanted with a cardiac resynchronization therapy defibrillators (CRT-D) device and an implantable cardioverter defibrillator (ICD). Although the ejection fraction (EF) in cardiac resynchronization therapy ...
Abreu, A; Oliveira, MM; Cunha, PS; Santa Clara, H; Portugal, G; Rodrigues, I; Santos, V; Almeida-Morais, L; Selas, M; Soares, R; Branco, LM INTRODUCTION: The benefits of cardiac resynchronization therapy (CRT) documented in heart failure (HF) may be influenced by atrial fibrillation (AF). We aimed to compare CRT response in patients in AF and in sinus rhythm (SR). METHODS: We prospectively studied 101 HF patients treated by CRT. Rates of clinical, echocardiographic and functional response, baseline NYHA class and variation, left ventricular ejectio... ...
TY - JOUR. T1 - Short-term hemodynamic effects of cardiac resynchronization therapy in patients with heart failure, a narrow QRS duration, and no dyssynchrony.. AU - Williams, LK. AU - Ellery, S. AU - Patel, K. AU - Leyva, F. AU - Bleasdale, RA. AU - Phan, TT. AU - Stegemann, B. AU - Paul, V. AU - Steendijk, P. AU - Frenneaux, M. PY - 2009/10/12. Y1 - 2009/10/12. N2 - Background- Cardiac resynchronization therapy produces both short-term hemodynamic and long-term symptomatic/mortality benefits in symptomatic heart failure patients with a QRS duration ,120 ms. This is conventionally believed to be due principally to relief of dyssynchrony, although we recently showed that relief of external constraint to left ventricular filling may also play a role. In this study, we evaluated the short-term hemodynamic effects in symptomatic patients with a QRS duration ,120 ms and no evidence of dyssynchrony on conventional criteria and assessed the effects on contractility and external constraint. Methods and ...
TY - JOUR. T1 - Association of corrected QT dispersion with symptoms improvement in patients receiving cardiac resynchronization therapy. AU - Hina, Kazuyoshi. AU - Kawamura, Hiroshi. AU - Murakami, Takashi. AU - Yamamoto, Keizo. AU - Yamaji, Hirosuke. AU - Murakami, Masaaki. AU - Hirohata, Satoshi. AU - Ogawa, Hiroko. AU - Sakane, Kohsuke. AU - Kusachi, Shozo. PY - 2008. Y1 - 2008. N2 - Cardiac resynchronization therapy (CRT) is theoretically expected to affect repolarization as well as depolarization. We studied the effects of CRT on corrected QT (QTc) dispersion in association with symptomatic improvement. QTc dispersion was analyzed in 26 consecutive patients (67 ± 6 years old, 18 men and 8 women) who underwent CRT. CRT responders and nonresponders were defined as patients showing and not showing ≥1 class New York Heart Association symptomatic improvement 3 months after CRT, respectively. QTc interval, QRS width, and QTc dispersion were measured automatically from digital data using an ...
TY - JOUR. T1 - Comparative Efficacy of Cardiac Resynchronization Therapy in Africans Americans Compared with European Americans. AU - Rickard, John. AU - Baranowski, Bryan. AU - Cheng, Alan. AU - Spragg, David. AU - Tedford, Ryan. AU - Mukherjee, Monica. AU - Tang, W. H.Wilson. AU - Wilkoff, Bruce L.. AU - Varma, Niraj. PY - 2015/10/1. Y1 - 2015/10/1. N2 - Race has seldomly been reported in the major clinical trials of cardiac resynchronization therapy (CRT). When described, African Americans (AAs) were substantially under-represented. This study sought to compare reverse ventricular remodeling and long-term outcomes in AAs versus European Americans (EAs) with advanced heart failure who underwent CRT. We extracted demographic (including race), clinical, and echocardiographic data on patients with advanced heart failure who underwent CRT with a left ventricular ejection fraction (LVEF) ≤35% and a QRS duration ≥120 ms. Long-term outcomes were compared between AAs and EAs. In patients in whom ...
Cardiac Resynchronization Therapy Reseda CA - Leo Polosajian, M.D. offers Cardiac Resynchronization Therapy (CRT). Our practice serves Reseda CA and surrounding areas.
Two recent studies in the Journal of the American College of Cardiology (JACC) look at findings from the MADIT-CRT (Multicenter Automatic Defibrillator Implantation Trial With Cardiac Resynchronization Therapy) Study. New data from MADIT-CRT study identifies who are the super-responders, and a second paper finds a possible new effect of statins. The first study looked at predictors of left ventricular ejection fraction (LVEF) super-response to cardiac resynchronization therapy with defibrillator (CRT-D) and whether super-response translated into improved, event-free survival in patients with mildly symptomatic heart failure (HF). Currently, few data exist on predictors of super-response to CRT-D and associated morbidity and mortality in mildly symptomatic HF populations. Based on the findings from the study, researchers concluded that six baseline factors predict LVEF super-response in CRT-D-treated patients with mild HF. These factors are: female sex, no prior myocardial infarction, QRS ...
© 2016 American College of Cardiology Foundation. Published by Elsevier. Objectives The goal of this study was to assess the contemporary and historical success rates of transvenous left ventricular (LV) lead placement for cardiac resynchronization therapy (CRT), their change over time, and the reasons for failure. Background In selected patients, CRT improves morbidity and mortality, but the placement of the LV lead can be technically challenging. Methods A literature search was used to identify all studies reporting success rates of LV lead placement for CRT via the coronary sinus (CS) route. A total of 164 studies were identified, and a meta-analysis was performed. Results The studies included 29,503 patients: 74% (95% confidence interval [CI]: 72% to 76%) were male; their mean age was 66 years (95% CI: 65 to 67); their mean New York Heart Association functional class was 2.8 (95% CI: 2.7 to 2.9); the mean LV ejection fraction was 26% (95% CI: 25% to 28%); and the mean QRS duration was 155 ms (95%
A large observational study published in JAMA suggests that patients with left bundle-branch block (LBBB) and longer QRS duration derive the most benefit from a cardiac resynchronization therapy defibrillator (CRT-D). The findings appear to support current, but often criticized, guidelines from the American College of Cardiology, American Heart Association, and the Heart Rhythm Society, in which a class I […]. ...
Considerable proportion of patients does not respond to the cardiac resynchronization therapy (CRT). This study investigated clinical relevance of left ventricular electrode local electrogram delay from the beginning of QRS (QLV). We hypothesized that longer QLV indicating more optimal lead placement in the late activated regions is associated with the higher probability of positive CRT response. We conducted a retrospective, single-centre analysis of 161 consecutive patients with heart failure and LBBB or nonspecific intraventricular conduction delay (IVCD) treated with CRT. We routinely intend to implant the LV lead in a region with long QLV. Clinical response to CRT, left ventricular (LV) reverse remodelling (i.e. decrease in LV end-systolic diameter - LVESD ≥10%) and reduction in plasma level of NT-proBNP |30% at 12-month post-implant were the study endpoints. We analyzed association between pre-implant variables and the study endpoints. Clinical CRT response rate reached 58%, 84% and 92% in the
In this study, subjects will be randomized to CRT-D or ICD-only. Randomization will be stratified by clinical center and ischemic status. Approximately 60% of the subjects will be randomly assigned to receive a CRT-D with biventricular pacing, and 40% will receive an ICD only. Optimal pharmacological therapy for heart failure will be required in both treatment arms. Length of follow-up for each subject will depend on the date of entry into the study, since all subjects will be followed to a common study termination date ...
Cardiac-resynchronization therapy (CRT) has known benefits in patients with severe left ventricular systolic dysfunction and prolonged QRS duration (,120 ms). However, up to half of patients with systolic dysfunction appear to have left ventricular dyssynchrony by echocardiographic measures, despite a QRS duration of less than 120 ms. As a result, CRT is often used for patients with echocardiographic evidence of dyssynchrony and a narrow QRS complex, despite a lack of clear benefit to this approach. The Echocardiography Guided Cardiac Resynchronization Therapy (EchoCRT) study sought to determine the effect of CRT on patient outcomes in the setting of symptomatic heart failure, echocardiographic findings of dyssynchrony, and QRS duration ,120 ms.. In this multicenter double blind trial, patients with severe symptomatic left ventricular failure (EF,35% and NYHA class III or IV) with a QRS duration of ,130ms (mean 105ms) and evidence of dyssynchrony either on tissue Doppler or speckle tracking echo ...
Umme Habiba Ferdaushi abstract presented on Short term outcome of cardiac resynchronization therapy on functional recovery of patients with congestive heart failure in Bangladeshi population at Euro Heart Failure 2017 | Conferenceseries Ltd
Introduction In selecting patients that may benefit from cardiac resynchronization therapy (CRT), dyssynchrony assessment by echocardiography based only upon the timing of regional contraction is limited by being inherently independent of underlying myocardial contractility. We hypothesised that patient selection may be enhanced using a strain-based parameter based not only on the timing of myocardial segmental motion, but also on the amplitude of contraction, a potential measure of contractile reserve. We assessed a combined early and late strain index (ELSI) to predict CRT response.. Methods Speckle tracking radial strain was performed in 42 patients scheduled for CRT (age 69 +/− 9 years, ischemic 56%, QRS 154 +/− 12ms, NYHA III/IV - 38/4, ejection fraction 23 +/− 7%). The ELSI was calculated as the sum, for each of the 12 non apical segments, of the difference in peak radial strain and strain at aortic valve closure. CRT response was defined as a ,15% reduction in LV end systolic volume ...
BACKGROUND: Cardiac resynchronization therapy improves systolic function in patients with heart failure and left ventricular (LV) dyssynchrony. However, the effect of biventricular (BiV) pacing on perioperative hemodynamics in cardiac surgery is not well known. We investigated the acute hemodynamic response using LVdP/dt(max) in patients with depressed LV function and conduction disturbances undergoing cardiac surgery.. METHODS: Patients with LV ejection fraction of , or =35%, QRS duration of ,130 ms, and left bundle branch block undergoing aortocoronary bypass and valve surgery were included. Temporary atrial and left and right ventricular pacing wires were applied, and LVdP/dt(max) was measured with a high fidelity pressure wire in the left ventricle at the end of cardiopulmonary bypass. Responders had a , or =10% increase in LVdP/dt(max).. RESULTS: Eleven patients (age 63 +/- 11 years, eight males) with a LV ejection fraction 0.29 +/- 0.06% were included. Compared with right ventricular ...
Left ventricular (LV) electrical activation pattern could determine optimal LV lead placement site during cardiac resynchronization therapy (CRT) device implant. We sought to determine the feasibility of using EnSite NavX™ electroanatomic mapping s
In cardiac resynchronization therapy (CRT), even if patient selection is made according to Japanese adaptive criteria, there are non-responders. Its main factor is consid..
APPROVAL FOR A MODIFICATION TO THE INDICATIONS FOR USE FOR THE COGNIS CRT-D MODELS N118, N119; LIVIANCRT-D MODELS H220, H225, H227 AND H229; AND CONTAK RENEWAL 3 RF HE CRT-D MODELSH210, H215, H217, H219 CARDIAC RESYNCHRONIZATION THERAPY DEFIBRILLATORS (CRT-DS) AS FOLLOWS:THESE BOSTON SCIENTIFIC CARDIAC RESYNCHRONIZATION THERAPY DEFIBRILLATORS (CRT-DS) ARE INDICATED FOR PATIENTS WITH HEART FAILURE WHO RECEIVE STABLE OPTIMAL PHARMACOLOGIC THERAPY (OPT) FOR HEART FAILURE AND WHO MEET ANY ONE OF THE FOLLOWING CLASSIFICATIONS:1) MODERATE TO SEVERE HEART FAILURE (NYHA CLASS III-IV) WITH EF = 120 MS; OR2) LEFT BUNDLE BRANCH BLOCK (LBBB) WITH QRS >= 130 MS, EF
The global cardiac resynchronization therapy (CRT) market is expected to reach USD 9.2 billion by 2025, according to a new report by Grand View Research, Inc. Increasing prevalence of cardiac disorders and rising incidences of heart failure are expected to boost the CRT market growth over the forecast period.. According to statistics published by the Sudden Cardiac Arrest Foundation in 2016, about 6.0 million people within the U.S. region suffer from cardiac disorders, of which 0.8 million are affected by atrioventricular block leading to cardiac failure. Such a huge number leads to an increased cost of about USD 20.0-56.0 billion annually. CRT devices are being predominantly used to prevent the surgical cost and readmission rate in hospitals, thereby propelling its growth.. In addition, the on-going research to develop smaller, wireless/leadless and long-lasting CRT devices is expected to be a vital impact rendering driver. For instance, in September 2016, EBR Systems Inc., announced that it ...
The DYNAGEN X4 CRT-D features 17 pacing vector options designed to resolve phrenic nerve stimulation and high thresholds. It brings forward the same long lasting battery technology as previous generations of Boston Scientific devices.
AIMS: Cardiac resynchronization therapy (CRT) has reportedly not been effective in the absence of electrical or mechanical dyssynchrony. We present six patients with severe left ventricular (LV) dilation, mitral regurgitation (MR), and non-ischaemic
Objective Ethnic and racial disparities in cardiac care may partially result from over-provision of care among white patients. We hypothesized that whites were more likely than blacks and Hispanics to receive cardiac resynchronization therapy with defibrillator (CRT-D) devices outside of ACC/AHA/HRS guidelines.. Methods We analyzed 01/2005- 04/2007 data from the ACC-National Cardiovascular Data Registry for implantable cardioverter-defibrillators (ICDs). We identified white, black and Hispanic patients who received CRT-D. We then fit a multivariable hierarchical logistic regression model with full ACC/AHA/HRS guideline concordance (QRS duration ,=0.12 ms, LVEF ,,26,35%, and class III or IV CHF) as a binary outcome. Independent variables included race/ethnicity, age, gender, cardiomyopathy etiology, duration of CHF, LVEF, blood pressure, QRS duration/morphology, prior coronary revascularization, atrial fibrillation, cerebrovascular disease, hypertension, diabetes, renal failure, and pulmonary ...
Clinical Long-Term Response to Cardiac Resynchronization Therapy Is Independent of Persisting Echocardiographic Markers of Dyssynchrony
Heart failure patients with a condition called heart block derive significant benefit from cardiac resynchronization therapy (CRT), according to the results of the Block HF clinical trial, presented at the American Heart Association Scientific Sessions 2012 meeting in Los Angeles. Anne B. Curtis, MD, Charles and Mary Bauer Professor and Chair of Medicine in the University at Buffalo School of Medicine and Biomedical Sciences is principal investigator of Block HF.
Cardiac Resynchronization Therapy (CRT), also referred to as biventricular pacing, is often recommended for patients with severe heart dysfunction and congestive heart failure (CHF). Learn more.
If youve been diagnosed with heart failure, learn about Medtronics Cardiac Resynchronization Therapy, what to expect during CRT surgery, & other heart failure resources.
The study of the Cardiac Resynchronization Therapy (CRT) Devices Market provides the market size information and market trends along with the factors an
Cardiac resynchronization therapy (CRT) helps the heart beat with healthy rhythm. CRT includes implanting an electronic device (pacemaker) under the skin to coordinate the timing of the contraction of the hearts lower chambers (ventricles), and improve the hearts pumping function.
Chalil, Shajil, Foley, Paul W X, Muyhaldeen, Sarkaw A, Patel, Kiran C R, Yousef, Zaheer R, Smith, Russell E A, Frenneaux, Michael P and Leyva, Francisco (2007) Late gadolinium enhancement-cardiovascular magnetic resonance as a predictor of response to cardiac resynchronization therapy in patients with ischaemic cardiomyopathy. EP-Europace, 9 (11). pp. 1031-7. ISSN 1099-5129 Full text not available from this repository. (Request a copy ...
|p|​Find out the key features and specifications for 13 cardiac resynchronization therapy pacemakers (CRT-Ps) from Biotronik, Boston Scientific, Medtronic, and St. Jude. View, analyze, and compare models and features using our downloadable matrix. |/p|
Care guide for Cardiac Resynchronization Therapy (Aftercare Instructions). Includes: possible causes, signs and symptoms, standard treatment options and means of care and support.
Definition : Implantable cardiac pacemaker and/or defibrillator/cardiac pacemakers leads used for sensing cardiac bioelectric signals and delivering electrical stimuli to synchronize ventricular contractions. These leads are connected to implantable cardiac pacemakers or defibrillator/cardioverter/pacemakers for resynchronization therapy in patients with advanced heart failure (e.g., dilated cardiomyopathy) and/or serious heart-rhythm problems such as delayed ventricular activation and contraction (i.e., ventricular dysynchrony).. Entry Terms : Biventricular Pacemaker/Implantable Cardioverter Defibrillators (Bi-V/ICDs) , Biventricular Pacemakers , Cardiac Resynchronization Therapy Leads , Ventricular Resynchronization Leads , Resynchronization Cardiac Rhythm Leads , Cardiac Resynchronization Therapy Defibrillator (CRT-D) Systems , Biventricular Pacing Devices , Defibrillation Electrodes , Electrodes, Defibrillation. UMDC code : 20377 ...
We expected to see a difference, but we were struck by the magnitude of these results, said Daniel B. Kramer, M.D., M.P.H., lead author of the study and assistant professor of medicine at Harvard Medical School in Boston, Massachusetts.. Patients functional status clearly predicts survival. Our hope would be to use activity as a factor in not just predicting outcomes but also to guide strategies that may improve outcomes. But that is much further down the line. Researchers studied the ALTITUDE registry, a nationwide database that involved 98,437 patients enrolled in a remote monitoring program. About 57 percent of the patients had received a new or replacement ICD and 43 percent had received cardiac resynchronization therapy cardiac resynchronization therapy (CRT-D) devices in 2008-12. CRT-D therapy combines an ICD with cardiac resynchronization therapy. Patients were followed for a median 2.2 years.. What is intriguing about our results is that looking at just one piece of information ...
BACKGROUND: Functional mitral regurgitation (FMR) is associated with reduced survival in dilated cardiomyopathy (DCM). Cardiac resynchronization therapy (CRT) can improve FMR. We sought to identify the predictors of FMR improvement after CRT in DCM. METHODS: From January 2003 to December 2013, 430 DCM patients consecutively enrolled were retrospectively analyzed. Inclusion criteria were successful CRT implantation in the presence of conventional indications (i.e., left bundle branch block, left ventricular ejection fraction ≤35%, New York Heart Association functional class ≥II) and moderate-to-severe FMR at the time of procedure. Early echocardiographic evaluation after CRT implantation (median 2.5 days) has been performed in each patient. Improvement in FMR (absent/mild) at midterm (7 months; interquartile range 4-10) was considered as the primary study end point. RESULTS: A total of 44 patients (10% of the overall cohort) were included. A significant reduction in FMR severity was observed ...
A pacing system computes optimal cardiac resynchronization pacing parameters using intrinsic conduction intervals. In various embodiments, values for atrio-ventricular delay intervals are each computed as a function of an intrinsic atrio-ventricular interval and a parameter reflective of an interventricular conduction delay. Examples of the parameter reflective of the interventricular conduction delay include QRS width and interval between right and left ventricular senses.
The patients included in this study, who presented with a long history of apparently isolated LBBB and progressive LV dysfunction, possessed the characteristics of an original syndrome suspected from previous animal experiments, epidemiological studies, and clinical observations, though never demonstrated in individual patients. These original observations strongly support the concept of LBBB-induced cardiomyopathy treatable with CRT.. Isolated LBBB causes abnormalities of LV dysfunction, manifest by a shortening of the filling time, a decreased septal contribution to LV ejection, and a globally depressed EF, compared with normal matched controls (5). High-amplitude oscillations of the interventricular septum were also described, similar to the septal flash, a sign of mechanical dyssynchrony (present in 4 of our 6 patients) and a putative predictor of echocardiographic response to CRT (16).. The clinical value of several techniques and measures proposed to detect and quantify LBBB-induced ...
Comparison of pharmacological treatment alone versus treatment combined with cardiac resynchronization therapy in patients over 75 years. Cruz, Elena; Cortés, Marcelino; Farré, Jerónimo; Palfy, Julia; Ávila, Paloma; Hernández, Ignacio; Romero, Angélica; Benezet, Juan; Franco, Juan; Navas, Miguel; Hernandez, Jose; Briongos, Sem; Rubio, José // Journal of Interventional Cardiac Electrophysiology;Jun2015, Vol. 43 Issue 1, p13 Background: The role of cardiac resynchronization therapy (CRT) in patients aged ≥75 years is not well established. Methods: We identified 607 patients aged ≥75 years with left ventricular ejection fraction (LVEF) of ≤35 %, of whom 78 met the guidelines for indication of CRT.... ...
LV endocardial pacing has been proposed and has been shown to be superior to conventional LV epicardial pacing in the CRT setting in computer simulations (54) and preclinical experiments (55,56). In various canine LBBB models, superiority has been shown in electrical resynchronization and acute hemodynamic response (55,56). However, clinical studies showed less reproducible differences. Derval et al. (57) was not able to show significantly better hemodynamic response between pacing in the endocardial position and immediately below the position of the coronary sinus lead, although in each patient there was an endocardial position that resulted in superior improvement in pump function. Similarly, Spragg et al. (58) found that endocardial pacing tended to be superior to epicardial pacing in patients with ischemic cardiomyopathy, but that the location of optimal LV endocardial pacing varied among patients. Shetty et al. (59) showed that LV endocardial pacing was superior to epicardial pacing and ...
This is generally performed subsequent to RV lead placement, with the RV lead providing a backup in case of accidental damage to the electric fibers of the heart, causing an asystolic event. As with the RV lead, a guide wire is first inserted, allowing for the insertion of a multi-delivery catheter. The catheter is subsequently maneuvered to the opening of the coronary sinus in the right atrium. From here a contrast media is injected, allowing the surgical team to obtain a coronary sinus phleobogram to direct the placement of the lead into the most suitable coronary vein.[1]. Once the phlebogram has been obtained, the multi-delivery catheter is used to guide in the lead, from the chosen vein of entry, into the right atrium, through the coronary sinus and into the relevant cardiac vein.[1]. Left ventricular lead placement is the most complicated and potentially hazardous element of the operation, due to the significant variability of coronary venous structure. Alterations in heart structure, ...
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The FDA approved two quadripolar leads for use in cardiac resynchronization therapy defibrillators for patients with heart failure.
Global Cardiac Resynchronization Therapy Device Market Professional Survey Report 2017 Purchase This Report by calling ResearchnReports.com at +1-888-631-6977.. The latest intelligence on the Cardiac Resynchronization Therapy Device market is available in the Global Cardiac Resynchronization Therapy Device Market Research report. This report is a culmination of the key events from last decade to present day, and helps to formulate the best strategy catered to both established market players and new entrants.. A birds eye view of the Cardiac Resynchronization Therapy Device industry made available in the report helps readers to understand the key drivers, restraints, challenges, and opportunities that are shaping the global Cardiac Resynchronization Therapy Device market. Furthermore, the report evaluates challenges experienced from buyers and sellers side. The report offers advice from key industry experts on how these challenges can be overcome.. A major chunk of the report talks about the ...
Looking for online definition of resynchronization therapy in the Medical Dictionary? resynchronization therapy explanation free. What is resynchronization therapy? Meaning of resynchronization therapy medical term. What does resynchronization therapy mean?
William S Weintraub Emory University May 2, 2005 Cost Effectiveness of Therapy With Abnormal LV Function Post-MI Dr. Al-Khatib and colleagues are to be commended for their evaluation of the cost-effectiveness of implantable cardioverter defibrillators (ICD) based on the Multicenter Automatic Defibrillator Implantation Trial-II (MADIT-II).1 At 20 months, mortality was 14.2% in the ICD group and 19.8% in the controls, an absolute difference of 5.6%.2 Cost in the ICD group was estimated at $131,490 and in the medical therapy group $40,661, a difference of $90,829, and a gain in life years of 1.8 years.(1) The authors find ICDs to be marginally cost-effective, with a base-case estimate of the incremental cost-effectiveness ratio (ICER) of $50,500 per life-year gained. Sensitivity analysis suggested that the ICER could vary greatly, from a somewhat lower to a great deal higher value, depending on the assumptions made. The ICER was especially sensitive to the effectiveness of the ICD. The MADIT-II ...
CRT-D device led to 72% reduction in death among female patients, study found.. Its the first time that a heart treatment has been shown to offer greater benefit to women, the researchers added.. The finding was unexpected, but extremely important, study author Dr. Arthur J. Moss, a professor of medicine at the University of Rochester Medical Center, said in a news release.. He and his colleagues looked at the effectiveness of cardiac resynchronization therapy with defibrillator (CRT-D) in 1,820 patients in Canada, Europe and the United States. CRT-D combines the benefits of both an implantable cardioverter defibrillator (ICD) and cardiac resynchronization therapy. ICDs prevent sudden, irregular rhythm-related cardiac death, and resynchronization therapy boosts heart function and reduces the risk of heart failure and related symptoms.. CRT-D is approved in the United States to treat patients with severe heart failure and those with mild heart failure to prevent them from progressing to ...
If your heart is not beating efficiently and you meet the eligibility criteria, you may be eligible for a cardiac resynchronization therapy (CRT) heart device. A cardiac resynchronization therapy device is designed to treat heart failure.. A CRT device sends small, undetectable electrical impulses to both lower chambers of the heart to help them beat together in a more synchronized pattern. This improves the hearts ability to pump blood and oxygen to the body. The heart device itself is actually a tiny computer, plus a battery, contained in a small titanium metal case that is about the size of a pocket watch. It weighs about 3 ounces.. In addition to the heart device, insulated wires called leads are implanted for two purposes: to carry information signals from your heart to the heart device, and to carry electrical impulses to your heart. The third part of your implantable device system is a programmer, an external computer located in your doctors office or clinic that is used to program the ...
Paper Survival with Cardiac-Resynchronization Therapy in Mild Heart Failure Presenter MD Summary BACKGROUND The Multicenter Automatic Defibrillator Implantation Trial with Cardiac Resynchro-nization Therapy (MADIT-CRT) showed that early intervention with cardiac-resyn-chronization therapy with a defibrillator (CRT-D) in patients with an electrocardio-graphic pattern showing left bundle-branch block was associated with a significant reduction in heart-failure events over…
A comparison of acoustic cardiography and echocardiography for optimizing pacemaker settings in cardiac resynchronization therapy
CIDS is the fourth reported randomized controlled trial that compared ICDs with antiarrhythmic drugs in recent years. The other 3 studies were the AVID (Antiarrhythmics versus Implantable Defibrillators) trial (1), the MADIT (Multicenter Automatic Defibrillator Implantation Trial) (2), and the CASH (Cardiac Arrest Study Hamburg) trial (3). CIDS allocated 600 patients to either ICD or amiodarone therapy. The current economic analysis limited itself to the first 430 patients. CIDS showed a small, statistically nonsignificant mortality advantage for patients in the ICD group, but the cost-benefit analysis showed a very high cost per year-of-life saved by ICDs. The authors concluded that ICD implantation was not cost-effective in these patients. Several points should be made about this study relative to its predecessors. First, the patient populations in these trials have been different. For example, the CIDS patients had resuscitated VF, VT, or unmonitored syncope, whereas the CASH patients had all ...
Quality of life was reported in 15 of the 25 trials. Overall, CRT was associated with an improvement in scores on the Minnesota Living with Heart Failure Questionnaire (MLHFQ) compared with control participants (14 trials, 4283 participants; WMD, 6.56 points [CI, 4.08 to 9.04 points]), but substantial statistical heterogeneity was found (I2 = 72%) that was largely attributable to symptom status at baseline. Two of the 3 trials (787 participants) including patients with NYHA class I or II symptoms had better MLHFQ scores at baseline (mean scores, 40 [35] and 28 [11]) and did not show any appreciable improvement with CRT (WMD, 1.82 points [CI, −0.77 to 4.41 points]; I2 = 0%). The remaining trial in patients with NYHA class I or II symptoms (12, 42) reported no difference between the CRT and control groups in Kansas City Cardiomyopathy Questionnaire scores (mean change at 12 months, 13.9 vs. 12.1, respectively; P = 0.059). In contrast, in the 12 trials (3496 patients) including predominantly ...
TY - JOUR. T1 - Prognostic effect and modulation of cardiac sympathetic function in heart failure patients treated with cardiac resynchronization therapy. AU - Moreira, Rita Ilhão. AU - Abreu, Ana. AU - Portugal, Guilherme. AU - Oliveira, Luís. AU - Oliveira, Mário. AU - Rodrigues, Inês. AU - Cruz, Madalena Coutinho. AU - Cunha, Pedro Silva. AU - Santos, Vanessa. AU - Clara, Helena Santa. AU - Carmo, Miguel Mota. AU - Ferreira, Rui Cruz. PY - 2020/2. Y1 - 2020/2. N2 - Background: Cardiac autonomic dysfunction as assessed by 123 I-metaiodobenzylguanidine ( 123 I-mIBG) scintigraphy is associated with poor prognosis in heart failure (HF) patients. Although cardiac resynchronization therapy (CRT) has emerged as an effective therapy in improving outcomes on HF patients, its effect on cardiac sympathetic nervous function is still not fully understood. We aimed to study the value of pre-implantation 123 I-mIBG late heart-to-mediastinum ratio (HMR) as a predictor of response and outcomes after CRT ...
Medtronic has received US Food and Drug Administration (FDA) approval for the Claria MRI Quad cardiac resynchronisation therapy defibrillator (CRT-D) SureScan device for patients with heart failure.. The Claria MRI CRT-D is approved for scanning in both 1.5 and 3 Tesla (T) magnetic resonance imaging (MRI) machines, and features EffectivCRT, a new algorithm that automatically tailors the therapy to individual patients by adjusting pacing rates.. Until now, CRT devices have shown only whether a pacing pulse was sent, but we have not been able to determine if that stimulation actually improves the hearts pumping ability, says Suneet Mittal, director, Electrophysiology Laboratory, Arrhythmia Institute of the Valley Health System, Ridgewood, USA. With the Claria device, physicians are now able to verify the effectiveness of left ventricular pacing, which is especially beneficial for improving outcomes in patients with atrial fibrillation, who have been difficult to treat because this irregular ...
Adabag S, Roukoz H, Anand IS, Moss AJ. Cardiac resynchronization therapy in patients with minimal heart failure: a systematic review and meta-analysis. J Am Coll Cardiol. 2011 Aug 23;58(9):935-41.. Allen LA, Stevenson LW, Grady KL, Goldstein NE, Matlock DD, Arnold RM, et al. Decision Making in Advanced Heart Failure: A Scientific Statement From the American Heart Association. Circulation. 2012 Apr 17;125(15):1928-1952. Epub 2012 Mar 5.. Al-Majed NS, McAlister FA, Bakal JA, Ezekowitz JA. Meta-analysis: cardiac resynchronization therapy for patients with less symptomatic heart failure. Ann Intern Med. 2011 Mar 15;154(6):401-12. Epub 2011 Feb 14.. Bibbins-Domingo K, Pletcher MJ, Lin F, Vittinghoff E, Gardin JM, et al. Racial differences in incident heart failure among young adults. N Engl J Med. 2009 Mar 19;360(12):1179-90.. Carlson MD, Wilkoff BL, Maisel WH, Carlson MD, Ellenbogen KA, Saxon LA, et al. Recommendations from the Heart Rhythm Society Task Force on Device Performance Policies and ...
Cardiovascular implantable electronic devices (CIEDs) with physical activity (PA) recording function can continuously and automatically collect patients long-term PA data. The dose-response association of implantable cardioverter-defibrillator (ICD) and cardiac resynchronization therapy defibrillator (CRTD)-measured PA with cardiovascular outcomes in patients at high risk of sudden cardiac death (SCD) was investigated. In total, 822 patients fulfilling the inclusion criteria were included and divided into three groups according to baseline PA tertiles: tertile 1 (| 8.04%, n = 274), tertile 2 (8.04-13.24%, n = 274), and tertile 3 (| 13.24%, n = 274). The primary endpoint was cardiac death, the secondary endpoint was all-cause mortality. During a mean follow-up of 59.7 ± 22.4 months, cardiac death (18.6% vs 8.8% vs 5.5%, tertiles 1-3, P | 0.001) and all-cause mortality (39.4% vs 20.4% vs 9.9%, tertiles 1-3, P | 0.001) events decreased according to PA tertiles. Compared with patients younger than 60
Abbott recieved CE mark approval for Gallant implantable cardioverter defibrillator (ICD) and cardiac resynchronization therapy defibrillator (CRT-D) in EU.
Medtronic has treated more than 140,000 heart failure patients with CRT, an implantable heart device that may improve the hearts ability to pump blood.
Types of artificial pacemakers with implantable leads to be placed at multiple intracardial sites. They are used to treat various cardiac conduction disturbances which interfere with the timing of contraction of the ventricles. They may or may not include defibrillating electrodes (IMPLANTABLE DEFIBRILLATORS) as well ...
Ventricular dysynchrony is something that often happens in patients who have heart failure. It is essentially the inability of the heart to beat in a coordinated fashion. This can be remedied in many cases using cardiac resynchronization therapy. This is simply a pacemaker that helps force the heart to beat in a coordinated manner. The advantages of having cardiac resynchronization therapy -- or CRT -- are that the patient can feel better, less shortness of breath, and can potentially walk farther.
10. The system of claim 1, wherein the processor is configured to control the electrical stimulation module to deliver the pacing stimulus to the first ventricle by at least: detecting a first atrial pace or sense event; and controlling the electrical stimulation module to deliver a first pacing stimulus after expiration of a first pacing interval from the first atrial pace or sense event, and wherein the processor is configured to determine whether the surrogate indication of intrinsic conduction from the atrium of the heart to the second ventricle of the heart of the patient is detected by at least: detecting, based on electrical cardiac activity sensed by the sensing module, a first activation of the second ventricle within the predetermined window of time immediately following delivery of the first pacing stimulus to the first ventricle; determining a first time interval between the first atrial pace or sense event and the first activation of the second ventricle and a second time interval ...
a. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the works authorship and initial publication in this journal.. b. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journals published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.. c. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).. ...
A method and apparatus for selection of one or more ventricular chambers to stimulate for ventricular resynchronization therapy. Intrinsic intracardia electrograms that include QRS complexes, are recorded from a left and right ventricle. A timing relationship between the intrinsic intracardia electrograms recorded from the left and right ventricle is then determined. In one embodiment, the timing relationship is determined using a delay between a left ventricular and a right ventricular sensed intrinsic ventricular depolarizations and a duration interval of one or more QRS complexes. In one embodiment, the duration of QRS complexes is determined from either intracardiac electrograms or from surface ECG recordings. One or more ventricular chambers in which to provide pacing pulses are then selected based on the timing relationship between intrinsic intracardia electrograms recorded from the right and left ventricle, and the duration of one or more QRS complexes.
June 23, 2009 - Today, Medtronic Inc. announced the first worldwide enrollments in the MORE-CARE (Monitoring Resynchronization in Cardiac Patients) trial, which will compare two disease management strategies for heart failure patients treated with an implantable device for cardiac resynchronization therapy. MORE-CARE aims to demonstrate that remote monitoring of these patients via the Medtronic CareLink Network is superior to in-office visits alone in terms of clinical effectiveness and healthcare system utilization.. The trial will utilize Medtronic wireless cardiac resynchronization therapy-defibrillators (CRT-Ds) equipped with OptiVol Fluid Status Monitoring and Medtronic CareAlert Notifications. The devices automatically notify a physician with a text message (SMS), e-mail or a Medtronic CareLink Web site message when certain pre-programmed thresholds are crossed without an in-office diagnosis by the physician. OptiVol CareAlert notifications are not available in the U.S., and no U.S. ...
Study To Assess Feasibility of First Application of Companys Proprietary Platform Technology to Improve Myocardial Efficiency. Proteus Biomedical Inc., a pioneer in intelligent medicine, announced today the initiation of the RETIME 2.0 (Resynchronization using Electric Tomography to Improve Myocardial Efficiency 2.0) study. RETIME 2.0 is designed to assess the performance of Proteus Biomedicals cardiac electric tomography (CET) and multi-sensor lead system for the measurement of cardiac performance in heart failure patients undergoing implantation of a cardiac resynchronization therapy (CRT) device.. Cardiac electric tomography is a proprietary, operator-independent modality developed by Proteus Biomedical. The first product application, in the field of heart failure, is intended to improve heart failure outcomes by objectively assessing the relative hemodynamic effect of lead placement sites during and after CRT device implantation, and by quantitatively tracking a range of standard cardiac ...
Heart failure (HF) has a prevalence of five million individuals in the United States. Approximately 25-30% of patients with HF due to left ventricular (LV) systolic dysfunction have prolonged QRS. Prolonged QRS duration (,120ms) on ECG in HF patients is associated with increased morbidity and mortality.. Delayed electrical activation of the LV translates to temporal delay in ventricular contraction. This is referred to as mechanical dyssynchrony. Patients with advanced HF, low ejection fraction (EF) of less than 35% and QRS of more than 120ms are indicated for cardiac resynchronization therapy (CRT). While most patients undergoing CRT implantation show dramatic improvement in HF symptoms, 30-40% of the HF patients undergoing CRT placement do not show a clinical response. The site of placement of the LV lead has been shown to be an important determinant of the effects of CRT.. Measurement of left ventricular ejection fraction (LVEF) is performed using non-invasive measures such as the MUGA. By ...
Cardiac resynchronization therapy (CRT) with biventricular (BV) pacing is an established therapy in approximately two-thirds of symptomatic heart failure (HF) patients (P) with left bundle branch block (LBBB). The aim of this study was to evaluate left atrial (LA) conduction delay (LACD) and left ventricular (LV) conduction delay (LVCD) using pre-implantational transesophageal electrocardiography (ECG) in sinus rhythm (SR) CRT responder (R) and non-responder (NR). Methods: SR HF P (n=52, age 63.6±10.4 years; 6 females, 46 males) with New York Heart Association (NYHA) class 3.0±0.2, 24.4±7.1 % LV ejection fraction and 171.2±37.6 ms QRS duration (QRSD) were measured by bipolar filtered transesophageal LA and LV ECG recording with hemispherical electrodes (HE) TO catheter (Osypka AG, Rheinfelden, Germany). LACD was measured between onset of P-wave in the surface ECG and onset of LA deflection in the LA ECG. LVCD was measured between onset of QRS in the surface ECG and onset of LV deflection in ...
The first part of the webinar will provide an overview of established and exciting, new applications of radionuclide imaging in heart failure. In the second part the speaker will describe how ECG-gated Myocardial Perfusion SPECT imaging is used to measure the regional onset of mechanical contraction as an indicator of LV intraventricular dyssynchrony (LVD). The session will also address how biventricular pacemakers are being used to treat systolic heart failure in patients with advanced left bundle branch block using Cardiac Resynchronization Therapy (CRT) and the role that LVD plays in predicting CRT response and assessing treatment. The potential of this use of LVD will be discussed under the results of the IAEA funded VISION-CRT study ...
Background: In recent years, catheter ablation has been widely used in the treatment of paroxysmal atrial fibrillation (AF). Radiofrequency ablation has long been standard of care, whereas cryoballoon ablation has emerged as a new alternative for the treatment of paroxysmal AF. The present study aims to investigate the efficacy and safety of radiofrequency ablation and cryoballoon ablation for paroxysmal AF. Subjects and Methods: This retrospective nonrandomized controlled study consecutively enrolled 582 patients with paroxysmal AF who underwent radiofrequency ablation or cryoballoon ablation for the first time in Nanjing Drum Tower Hospital from September 2014 to October 2018. The enrolled patients were divided into four groups according to the ablation energy source used and instruments: normal saline irrigation catheter group (Group A), contact force-sensing catheter group (Group B), first-generation cryoballoon group (Group C), and second-generation cryoballoon group (Group D). The ...
With the development of Dyssynchrony Imaging, Toshiba is providing cardiologists with a new innovation that expands the quantification capabilities of ultrasound to aid in diagnosing cardiovascular disease, said Gordon Parhar, director, Ultrasound Business Unit, Toshiba America Medical Systems, Inc. The DI method makes it easier for clinicians to determine the severity of dyssynchrony by having an automated detection of maximum values and a visual display of time to peak for each region. DI also will be a valuable tool in assessing patients for cardiac resynchronization therapy, providing clinicians with a pathway treatment from pre-implant to post implantation of the pacemaker ...
Accidental malpositioning of a right ventricular (RV) electrode has not been previously reported in the context of cardiac resynchronization therapy (CRT). The case of a 75-year old male patient with dilative cardiomyopathy, left ventricular (LV) ejection fraction 23%, New York Heart Association functional heart failure status stage III, left bundle branch block (LBBB) with QRS width of 136 ms, and misplacement of the RV lead to the LV apex during implantation of a CRT defibrillator is described. Following unremarkable implantation, routine interrogation of the CRT device on the first day after the implantation revealed uneventful technical findings. The 12-lead surface electrocardiogram (ECG) showed biventricular stimulation featuring a narrow QRS complex with incomplete right bundle branch block (RBBB) and R|S in V1. The biplane postoperative chest X-ray was graded normal. On routine follow-up one month later, a transthoracic echocardiogram revealed an increased ejection fraction of 51% but the RV
We read with great interest the paper by Carluccio et al. (1) regarding the impact of left ventricular (LV) remodeling on the response to cardiac resynchronization therapy (CRT). In this elegant study, the authors performed a comprehensive assessment of LV function, showing that extensive LV remodeling at baseline is associated with poor improvement after CRT.. We wish to raise an essential issue, which may be of keen interest to the readers.. In recent years, there has been growing interest in the potential impact of CRT on atrial function, but the state of knowledge in this field is still controversial and unsettled (2-4). In the paper by Carluccio et al. (1) several baseline data concerning atrial function are presented (left atrial volume index and mitral regurgitation severity), but unfortunately there is no information related to CRT response. We believe that their excellent echocardiographic data could also be useful to better understand another debated issue (i.e., the effect of CRT on ...
Aims. The independent clinical correlates and prognostic impact of QRS prolongation in heart failure (HF) with reduced and preserved ejection fraction (EF) are poorly understood. The rationale for cardiac resynchronization therapy (CRT) in preserved EF is unknown. The aim was to determine the prevalence of, correlates with, and prognostic impact of QRS prolongation in HF with reduced and preserved EF.. Methods and results. We studied 25 171 patients (age 74.6 ± 12.0 years, 39.9% women) in the Swedish Heart Failure Registry. We assessed QRS width and 40 other clinically relevant variables. Correlates with QRS width were assessed with multivariable logistic regression, and the association between QRS width and all-cause mortality with multivariable Cox regression. Pre-specified subgroup analyses by EF were performed. Thirty-one per cent had QRS ≥120 ms. Strong predictors of QRS ≥120 ms were higher age, male gender, dilated cardiomyopathy, longer duration of HF, and lower EF. One-year survival ...
DISCUSSION. The greatest advantage of the S-ICD is avoiding the implantation of leads within cardiovascular system, thus preserving central venous circulation, with no risks of mechanical traumas, such as vascular damages or pneumothorax, and with a very low risk of systemic infection[8]. An important disadvantage is the impossibility of the system to provide heart pacing. For this reason, it is contraindicated for patients with indication for bradycardia pacing, cardiac resynchronization therapy or antitachycardia pacing (ATP) since S-ICD cannot provide cardiac pacing other than for a short period post-shock, when necessary[9]. Based on the benefits and after pre-selecting the patients, this new technology was chosen to be used.. After selecting the patients, they were submitted to the screening phase using a customized plastic ruler supplied by the manufacturer with the purpose of evaluating if the generated electric signal would be able to provide an appropriate functioning of the S-ICD. ...
MINNEAPOLIS & BOSTON--(BUSINESS WIRE)--May 10, 2012-- Medtronic, Inc.. (NYSE: MDT) today announced results from the first and only clinical trial to show that Medtronic cardiac devices can safely extend detection time before triggering therapy in primary and secondary prevention patients. The ADVANCE III study, presented today as a late-breaking presentation at Heart Rhythm 2012, the Heart Rhythm Societys 33rd Annual Scientific Sessions, evaluated patients with implantable cardioverter defibrillator (ICD) and cardiac resynchronization therapy with defibrillation (CRT-D), and found devices programmed with longer duration (increased number of intervals) to detect arrhythmias provided therapy (shocks and anti-tachycardia pacing, ATP) only when needed and without increased risk to patients.. Patients in the study were randomized to two groups: an extended detection (30/40 intervals) and the standard detection interval (18/24 intervals). The study met its primary endpoint by demonstrating a 37 ...
In the early stages of heart failure, a doctor may suggest lifestyle changes such as a low sodium diet and regular exercise. As the disease progresses, medications or an implanted device, such as a cardiac resynchronization therapy (CRT) device may be necessary to help the heart continue beating more efficiently. CRT technology resynchronizes the lower chambers of the heart by sending uniquely programmed electrical impulses to stimulate each ventricle to beat in sync and offer optimal cardiac performance. A new technology, the CardioMEM HF System, is designed to help physicians monitor pressures near the heart, which can increase weeks before fluid builds up and symptoms occur. This monitoring allows the doctor to proactively adjust medications to lower pressures, avoiding symptoms and possible hospitalizations. Late stage heart failure therapy options include a left-ventricular assist device (LVAD), which is a mechanical heart pump that helps circulate blood throughout body when the heart cant ...
St. Jude Medical recently announced that patient enrollment has begun in the Atrial Fibrillation Suppression Pacing in Cardiac Resynchronization Therapy Devices (CRT-D) clinical study.
The report segments the global electrophysiology devices market according to three criteria: electrophysiology monitoring devices, electrophysiology treatment devices, and key regional markets. The segment of electrophysiology monitoring devices is further categorized into electrocorticograph (ECoG), electrocardiograph (ECG), electroencephalograph (EEG), electrooculograph (EOG), imaging and 3D mapping systems, electroretinograph (ERG), holter monitoring devices, X-ray systems, diagnostic electrophysiology catheters, and electromyograph (EMG).The segment of electrophysiology treatment devices is further divided into implantable cardioverter defibrillators (ICDs), cardiac resynchronization therapy devices (CRT), catheters, and pacemakers.. Geographically, the market is segmented into North America, Europe, Asia-Pacific, and the Rest of the World. Of these regional markets, North America accounted for the largest share of revenues in 2012, followed by Europe. In developed countries such as United ...
Findings advance opportunities for a pacemaker in a bottle. Johns Hopkins heart researchers are unraveling the mystery of how a modified pacemaker used to treat many patients with heart failure, known as cardiac resynchronization therapy (CRT), is able to strengthen the heart muscle while making it beat in a coordinated fashion. In a new study conducted on animal heart cells described in the Journal of Clinical Investigation, the scientists show that CRT changes these cells so they can contract more forcefully. The researchers also identified an enzyme that mimics this effect of CRT without use of the device.. These discoveries potentially give us new pathways to benefit more heart failure patients - not only those whose hearts beat out of sync, but also those who currently do not qualify for CRT therapy yet still need an effective treatment to help their heart pump stronger, says David Kass, M.D., professor of medicine and biomedical engineering at the Johns Hopkins University School of ...
We offer the full breadth of the most advanced, leading-edge protocols for the diagnosis and treatment of cardiac rhythm abnormalities, also known as arrhythmias. These include device therapies, invasive EP studies and interventional electrophysiology.. Device-based treatments include pacemakers for slow rhythms, implantable cardiac defibrillators (ICDs) for abnormally fast rhythms that can result in sudden death, and cardiac resynchronization therapy (biventricular devices) for advanced heart failure.. Interventional electrophysiology utilizes radiofrequency energy (heat) or cryotherapy (cold) to selectively ablate or eliminate the source or the structures critical for an arrhythmia to perpetuate. The target for ablation can be pinpointed with an invasive EP study, where electrode catheters are strategically placed in the heart, permitting precise mapping of an arrhythmia.. Interventional cardiology includes:. ...
2. Device based monitoring features in heart failure. BIV = biventricular pacing; CRT = cardiac resynchronization therapy; RV = right ventricle; ICD = implantable cardioverterdefibrillator; VT = ventricular tachycardia; VF = ventricular fibrillation; NSVT = non-sustained ventricular tachycardia; AF = atrial fibrillation; AT = atrial tachycardia. 3 Advantages of Remote Monitoring Systems Telemedicine, in general, is recognized by governmental and medical agencies as an innovation for improving the access to healthcare services, with a potential reduction in patient hospital stays related to cardiac events [2]. As a result, colored water injected from the inlets were ejected from the outlet without leaking through the only simply contacted seals between the lid and the resist film. On the other hand, it was clarified that if two colored waters were injected from the Y-shape inlets, they flew as two parallel flows, and not mixed at all, as shown in Fig. 16. 6 mm/s. Therefore, Reynolds ...
8) Union of India, by filing an affidavit before this Court, submitted that most of the claims are reimbursed only through the CGHS sources as per the package rates of CGHS. However, there are few such cases received occasionally where reimbursement is done from two sources i.e. from CGHS and from the insurance companies. Such claims are first processed by insurance companies and then by the CGHS. The claim of CGHS is reimbursed as per the Office Memorandum dated 19.02.2009. It is further submitted that no such cases involving reimbursement from two sources is pending in CGHS.. 9) Further, the writ petitioner was admitted in emergency condition with complaint of breathlessness on 11.11.2013 in Fortis Escorts Health Institute, which was a non-empanelled hospital at the relevant time. He underwent angiography on 12.11.2013 which revealed diffused disease in left anterior descending coronary artery 50-60%. He had been implanted the CRT-D device (Combo) as part of cardiac resynchronization therapy ...
Nevertheless, risk stratification is insufficient for demonstrating clinical utility, with the need to show utility in guiding therapy. HMR can help monitor the clinical course of patients on standard HF medications,20-23 but as HMR is unlikely to significantly influence the use of such medications, an area of investigation has been potential use of 123I-mIBG to guide invasive, expensive therapies. As a deteriorating HMR while on comprehensive medical therapy indicates a poor prognosis,24 some have suggested that 123I-mIBG imaging could help select patients needing interventions such as cardiac resynchronization therapy,25 a left ventricular assist device (LVAD), or cardiac transplantation.26,27 A few small studies have shown that 123I-mIBG imaging may help select LVAD patients who are improving sufficiently to defer potential transplant and perhaps explant the device.28,29. A major focus has been on the ability of 123I-mIBG imaging to risk stratify patient for risk of ventricular arrhythmic ...
Main article: Cardiac resynchronization therapy. Cardiac resynchronization therapy (CRT) is used for people with heart failure ... "Cardiac resynchronization therapy: a decade of experience and the dilemma of nonresponders". Texas Heart Institute Journal. 38 ... Cardiac stress test Bruce protocol. Electrophysiology study. Cardiac imaging. Angiocardiography. Echocardiography TTE. TEE. ... Ramsdale, David R. (2012). Cardiac pacing and device therapy. Rao, Archana. London: Springer. ISBN 978-1-4471-2939-4. . OCLC ...
In some moderate or severe cases cardiac resynchronization therapy (CRT) may be suggested[17] or cardiac contractility ... "Cardiac-Resynchronization Therapy in Heart Failure with a Narrow QRS Complex". N Engl J Med. 369 (15): 1395-405. doi:10.1056/ ... biventricular cardiac resynchronization therapy (CRT) can initiate a normal sequence of ventricular depolarization. In people ... insertion of an implantable cardioverter-defibrillator or cardiac resynchronization therapy. Echocardiography can also help ...
Applications include atrial fibrillation and cardiac resynchronization therapy. Pre-operative MRI or CT is used to plan the ... In cardiac surgery, shared control systems can perform mitral valve replacement or ventricular pacing by small thoracotomies. ...
In addition, this approach has been applied in cardiac resynchronization therapy (CRT) as a new biological pacemaker as a ... Nussinovitch U, Gepstein L (July 2015). "Optogenetics for in vivo cardiac pacing and resynchronization therapies". Nature ... A recent study explored the possibilities of optogenetics as a method to correct for arrythmias and resynchronize cardiac ... July 2017). "Optogenetic termination of ventricular arrhythmias in the whole heart: towards biological cardiac rhythm ...
He contributed to Clinical Cardiac Pacing, Defibrillation and Resynchronization Therapy. Eindhoven, 3w Media. "Frits Prinzen". ... Prinzen is an expert on cardiac pacing therapies, both for bradycardia and for heart failure (cardiac resynchronisation therapy ... CRT). Prinzen works on cardiac pacing therapies, both for bradycardia and for heart failure (cardiac resynchronisation therapy ... www.sciencedirect.com/book/9780323378048/clinical-cardiac-pacing-defibrillation-and-resynchronization-therapy Overview at peer ...
Registration with Adjacent Anatomical Structures for Cardiac Resynchronization Therapy Guidance. Statistical Atlases and ... However, over the last few years, there has been a growing interest in the predictive assessment of disease or therapy course. ... Image-based patient-specific modelling, combined with models of medical devices and pharmacological therapies, opens the way to ...
"Building a pipeline for in-silico modelling of cardiac resynchronization therapy". vph-noe. p. 11. Archived from the original ... from medical images to characterization and quantification of myocardial diseases and Cardiac Resynchronization Therapy (CRT) ... "Advance Tool for Visualization of Multi-modal and Multi-scale Cardiac Data" (PDF). UPF. p. 42. Archived from the original (PDF ... Gimias has been used to develop clinical prototypes in the fields of cardiac imaging and simulation, angiography imaging and ...
10 October 2013). "Cardiac-Resynchronization Therapy in Heart Failure with a Narrow QRS Complex" (PDF). N Engl J Med. 369 (15 ... Cardiac Resynchronization-Heart Failure (CARE-HF) Study Investigators. (2005). "The effect of cardiac resynchronization on ... 2004). "Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure". N ... or less and a QRS interval of 120 ms or more may benefit from cardiac resynchronization therapy (CRT; pacing both the left and ...
Recent studies suggest that cardiac resynchronization therapy can reduce the incidence of ventricular dyssynchrony and thus ... "Review - The Pathology of Ventricular Dyssynchrony and the Role of Cardiac Resynchronization Therapy". Medscape. Retrieved 13 ... Large differences in timing of contractions can reduce cardiac efficiency and is correlated with heart failure. Three chief ... increase cardiac efficiency. Bundle branch block Ejection fraction Pacemaker syndrome Speckle tracking echocardiography ...
... therapy in South Asia. He is also credited with the introduction of Cardiac Resynchronization Therapy in India. He is a ... Implantable cardioverter-defibrillator Cardiac Resynchronization Therapy India portal Medicine portal "K.K. Talwar on WHFS". ... In 2000, he brought the Cardiac Resynchronization Therapy to India for the first time. The introduction of multisite pacing ... His work on Cardiac arrhythmia helped develop it as a specialty in India and he was associated with Heart transplant program at ...
Relation of cardiac output to QRS duration during temporary resynchronization therapy after cardiac surgery. ASAIO J. 2010; ... also known as cardiac resynchronization therapy), which involves installation of pacemakers to fix delays in heart ventricle ... Cardiac output measurement by arterial pressure waveform analysis during optimization of biventricular pacing after cardiac ... Surgical Considerations of Pacemakers and Automatic Defibrillators, in Cohn L, Cardiac Surgery in the Adult. Spotnitz HM. 2nd ...
... with a cardiac resynchronization therapy device". Journal of Zoo and Wildlife Medicine. 42 (2): 263-276. doi:10.1638/2009- ... "Surgical implantation of a cardiac resynchronization therapy device in a western lowland gorilla (Gorilla gorilla gorilla) with ... Heart disease was the cause of 16 of the 52 deaths at Yakex primate research center between 1992 and 2005, and cardiac biopsies ... The gorilla's heart fibrosis has been distributed in an unorderly manner in the cardiac muscle as seen in human.[citation ...
Indications for cardiac resynchronization therapy: 2011 update from the Heart Failure Society of America guideline committee. J ... Patients with LBBB require complete cardiac evaluation, and those with LBBB and syncope or near-syncope may require a pacemaker ... Left bundle branch block (LBBB) is a cardiac conduction abnormality seen on the electrocardiogram (ECG). In this condition, ... hypertension leading to aortic root dilatation and subsequent aortic regurgitation Lyme disease Side effect of some cardiac ...
Cardiac resynchronization therapy (CRT) may be necessary , If other measures are not effective a heart transplant may be an ... Cardiac Myosin Binding Protein C (MYBPC3), Myosin Heavy Chain 7 (MYH7), Cardiac Troponin T 2 (TNNT2), and Cardiac Troponin I ( ... Drug therapy can slow down progression and in some cases even improve the heart condition. Standard therapy may include salt ... A computation model of volumetric, isotropic, and cardiac wall growth predicts the relationship between cardiac strains (e.g. ...
"Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure". N Engl J Med ... "The effect of cardiac resynchronization on morbidity and mortality in heart failure". N. Engl. J. Med. 352 (15): 1539-49. doi: ... "The effect of cardiac resynchronization on morbidity and mortality in heart failure". N Engl J Med 352 (15): 1539-49. doi: ... "Pacemakers and Implantable Cardiac Defibrillators: Software Radio Attacks and Zero-Power Defenses"(PDF). {{{booktitle}}}. 2008- ...
"What Is a Cardiac Resynchronization Therapy Device?". Medtronic. "U.S. Supreme Court tosses out Medtronic pacemaker patent loss ... which dealt with cardiac resynchronization therapy, a pacemaker that is used to treat congestive heart failure. Medtronic ...
cardiac resynchronization therapy. *by specific molecules: molecular therapy (although most drugs are specific molecules, ... First-line therapy (sometimes called induction therapy, primary therapy, or front-line therapy)[2] is the first therapy that ... palliative therapy See supportive therapy for connotative distinctions. preventive therapy. (prophylactic therapy) A therapy ... salvage therapy (rescue therapy) A therapy tried after others have failed; it may be a "last-line" therapy. ...
On September 25, 2004, Babec became the first gorilla to undergo the successful implant of a cardiac resynchronization therapy ...
"Long-Term Prognosis After Cardiac Resynchronization Therapy Is Related to the Extent of Left Ventricular Reverse Remodeling at ... Besides, the cardiac interstitium which consisted of largely Type I and Type III collagen fibres are also involved in cardiac ... Ventricular Reverse Remodeling but Not Clinical Improvement Predicts Long-Term Survival After Cardiac Resynchronization Therapy ... Besides, reduced expression of V1 mysoin and L-type calcium channels on cardiac myocytes are also thought to cause cardiac ...
... and cardiac resynchronization therapy to prevent sudden cardiac death. However, in view of reversible cardiomyopathy, sometimes ... or Cardiac resynchronization therapy (CRT) are not routinely used and reserved for severe LV dysfunction or high risk cases. ... Antiviral therapy, immunoabsorption, intravenous gamma globulin, or other immunomodulation therapy may then be considered ... including cardiac magnetic resonance imaging (MRI), cardiac catheterization, and endomyocardial biopsy for special staining and ...
... its 2019 remake Cardiac resynchronization therapy Cardio-thoracic ratio, a measure of the size of heart Carpal tunnel release, ...
... an enzyme Cardiac resynchronization therapy pacemaker This disambiguation page lists articles associated with the title CRTP. ...
... the rate at which blood refills empty capillaries Cardiac resynchronization therapy, a treatment for heart failure, and CRT ... a dementia treatment Corneal Refractive Therapy, in optometrics CRT (genetics), a gene cluster Cathode-ray tube, vacuum tube ... the combination of chemotherapy and radiotherapy to treat cancer Cognitive Retention Therapy, ...
Imaging of Cardiac Anatomy", Clinical Cardiac Pacing, Defibrillation and Resynchronization Therapy (Fifth Edition), Elsevier, ... Papillary muscles and chordae tendineae Play media Ultrasound showing redundant chordae tendineae Cardiac cycle Faletra, ...
Simple regional strain pattern analysis to predict response to cardiac resynchronization therapy: rationale, initial results, ... additional echo criteria for selection of Heart failure patients with LBBB who may respond to Cardiac resynchronization therapy ... Movements of the base of the ventricle and relative constancy of the cardiac volume. Am J Physiol 1932;102:559-65. Hoffman EA, ... It has an advantage over Ejection fraction (EF), it shows reduced cardiac function also in hypertrophic hearts with small ...
... and cardiac resynchronization therapy. 2004: Canadian Medical Association Award for Young Leaders 2015: Fellowship in the ... followed by a Heart and Stroke Foundation Fellowship in cardiac electrophysiology at the University of Western Ontario in 1999 ... of Policy Studies at Queen's University and completed a 10-year term as Chief of Cardiology and Medical Director of the Cardiac ...
Cardiac Resynchronization Therapy Cathode Ray Tube Chinese Remainder Theorem CRTC - (i) Canadian Radio-television and ... Cognitive Behaviour Therapy (p) Combat CBUS - (i) Columbus, Ohio CC - many, including carbon copy; see entry CCA - (i) Counter ... Cardiac Rhythm Management - Customer Relationship Management CRO - (s) Croatia (IOC and FIFA trigram, but not ISO 3166) CRP (i ...
... cardiac resynchronization therapy (CRT), laser lead extraction and ablation of atrial fibrillation and ventricular tachycardia ... "precise electrical measurements at the tip of a cardiac catheter, providing cardiac specialists with both numbers and a visual ... He has published research into complex ablation and pioneered cardiac ablation methods. Khaykin attended the University of ... 2009). "Cost Comparison of Ablation Versus Antiarrhythmic Drugs As First-Line Therapy for Atrial Fibrillation: An Economic ...
Main article: Cardiac resynchronization therapy. Cardiac resynchronization therapy (CRT) is used for people with heart failure ... "Cardiac resynchronization therapy: a decade of experience and the dilemma of nonresponders". Texas Heart Institute Journal. 38 ... Three leads can be seen in this example of a cardiac resynchronization device: a right atrial lead (solid black arrow), a right ... "The effect of cardiac resynchronization on morbidity and mortality in heart failure". N. Engl. J. Med. 352 (15): 1539-49. doi: ...
"Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure". N Engl J Med ... "The effect of cardiac resynchronization on morbidity and mortality in heart failure". N. Engl. J. Med. 352 (15): 1539-49. doi: ... "The effect of cardiac resynchronization on morbidity and mortality in heart failure". N Engl J Med. 352 (15): 1539-49. doi: ... Halperin, Daniel (2008). Pacemakers and Implantable Cardiac Defibrillators: Software Radio Attacks and Zero-Power Defenses (PDF ...
"Cardiac resynchronization therapy" - news · newspapers · books · scholar · JSTOR (August 2016) (Learn how and when to remove ... "Cardiac Resynchronization Therapy and Implantable Cardioverter Defibrillator Therapy in Advanced Heart Failure". Heart Failure ... "Cardiac Resynchronization Therapy Technique: Approach Considerations, Placement of Pacing Leads, Programming of Device". ... Chest radiographs of cardiac resynchronization therapy with defibrillator (CRT-D) in an individual with dilated cardiomyopathy ...
... on cardiac pacing and cardiac resynchronization therapyThe Task Force on cardiac pacing and resynchronization therapy of the ... on cardiac pacing and cardiac resynchronization therapyThe Task Force on cardiac pacing and resynchronization therapy of the ...
"2013 ESC guidelines on cardiac pacing and cardiac resynchronization therapy: the task force on cardiac pacing and ... and Cardiac Electrophysiology: Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular ... and Cardiac Electrophysiology: Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular ... middle cardiac vein, small cardiac vein, anterior cardiac veins[f]. ...
... implantable cardioverter defibrillators and cardiac resynchronization devices). *Discography, an invasive diagnostic procedure ... This is useful for both diagnosis and therapy and occurs in general radiology, interventional radiology, and image-guided ...
In the 1980s, Mower improved his original defibrillator by redesigning the AICD to administer resynchronization therapy. ... In 1989, Mower became Vice President of Medical Science at Cardiac Pacemakers Inc. in St. Paul, Minnesota. While at Cardiac ... Cardiac Pacemakers, Inc. (CPI), which has since become Guidant, acquired the rights to the AICD in May 1985. The first AICD was ... Cardiac Electrode with Attachment Fin. Atrial Sensing and Multiple Site Stimulation as Intervention Means for Atrial ...
Specifically cardiac resynchronization, administration of beta blockers and angiotensin converting enzyme inhibitors are ... Many of these therapies are effective in reducing the extent of cardiac dilation and increasing ejection fraction in HFrEF ... Pharmacologic therapy[edit]. Indications[edit]. Management of HFpEF is primarily dependent on the treatment of symptoms and ... Cardiac output is dependent on stroke volume and heart rate. A significant portion (55-77%) of HFpEF patients are unable to ...
Clinical Cardiac Pacing, Defibrillation and Resynchronization Therapy (Fifth Edition), Elsevier, pp. 739-834, ISBN 978-0-323- ... The middle cardiac vein has a constant location on the surface of the ventricles. The middle cardiac vein is useful for ... The middle cardiac vein commences at the apex of the heart; ascends in the posterior longitudinal sulcus, and ends in the ...
Many of these therapies are effective in reducing the extent of cardiac dilation and increasing ejection fraction in HFrEF ... Specifically cardiac resynchronization, administration of beta blockers and angiotensin converting enzyme inhibitors are ... Cardiac macrophages are thought to play an important role in the development of fibrosis as they are increased in HFpEF and ... Cardiac output is dependent on stroke volume and heart rate. A significant portion (55-77%) of HFpEF patients are unable to ...
"IPS Cell Intervention Rescues Wall Motion Disparity Achieving Biological Cardiac Resynchronization Post-Infarction". The ... The Future MSC-Based Therapy?". Mesenchymal Stem Cell Therapy. pp. 39-61. doi:10.1007/978-1-62703-200-1_3. ISBN 978-1-62703-199 ... Meanwhile, advances in the methods of obtaining cardiac myocytes in vitro occurred. Efficient cardiac differentiation of human ... in situ represents a promising strategy for cardiac regeneration. Mice exposed in vivo, to three cardiac transcription factors ...
"Cardiac Contractility Modulation in Non-responders to Cardiac Resynchronization Therapy" (PDF). Europace. 10 (12): 1375-1380. ... In Cardiac Contractility Modulation therapy, electrical stimulation is applied to the cardiac muscle during the absolute ... Artificial cardiac pacemaker Implantable cardioverter-defibrillator NYHA classification Cardiac resynchronization therapy ... Cardiac resynchronization therapy (CRT; also known as biventricular pacing) has proven to be an effective treatment in heart ...
Cardiac Anatomy and Pathology", Clinical Cardiac Pacing, Defibrillation and Resynchronization Therapy (Fifth Edition), Elsevier ... The small cardiac vein receives blood from the posterior portion of the right atrium and ventricle. The small cardiac vein may ... The small cardiac vein, also known as the right coronary vein, is a coronary vein that drains the right atrium and right ... The small cardiac vein runs in the coronary sulcus between the right atrium and right ventricle, and opens into the right ...
Cardiac resynchronization therapy (CRT) is used for people with heart failure in whom the left and right ventricles do not ... Ganjehei L, Razavi M, Massumi A (2011). "Cardiac resynchronization therapy: a decade of experience and the dilemma of ... Ramsdale, David R. (2012). Cardiac pacing and device therapy. Rao, Archana. London: Springer. ISBN 978-1-4471-2939-4. OCLC ... "The effect of cardiac resynchronization on morbidity and mortality in heart failure" (PDF). N. Engl. J. Med. 352 (15): 1539-49 ...
... implantable cardioverter defibrillators and cardiac resynchronization devices) Discography, an invasive diagnostic procedure ... This is useful for both diagnosis and therapy and occurs in general radiology, interventional radiology, and image-guided ... vascular imaging and cardiac catheterization. A number of substances have been used as radiocontrast agents, including silver, ...
Cardiac resynchronisation therapy (CRT or CRT-P) is the insertion of electrodes in the left and right ventricles of the heart, ... a cardiac abnormality leading to delayed left ventricular contraction. LBBB causes a QRS prolongation of >120 ms on the ...
Cardiac resynchronization therapy (CRT) helps the heart beat with healthy rhythm. CRT includes implanting an electronic device ... How Is Cardiac Resynchronization Therapy Done?. * Definition *What is cardiac resynchronization therapy? ... how is cardiac resynchronization therapy done center /how is cardiac resynchronization therapy done article ... Cardiac resynchronization therapy (CRT) is a treatment to help the heart beat with healthy rhythm. CRT is a minor surgical ...
The basic goal of cardiac resynchronization therapy (CRT) is to restore synchrony of the left ventricle in patients with ... encoded search term (Cardiac Resynchronization Therapy) and Cardiac Resynchronization Therapy What to Read Next on Medscape. ... 2013 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy: the Task Force on cardiac pacing and ... Cardiac resynchronization therapy (CRT) has been solidly established as an important advanced heart failure (HF) therapy to ...
For heart failure patients with few options, this cardiac resynchronization therapy could be a lifesaver ...
... Aka: Cardiac Resynchronization Therapy, Cardiac ... Cardiac Resynchronization Therapy, Cardiac Resynchronization Implantable Device. ... These images are a random sampling from a Bing search on the term "Cardiac Resynchronization Therapy." Click on the image (or ... Arterial Cannulation Arterial Puncture Automated External Defibrillator Cardiac Catheter Ablation Cardiac Resynchronization ...
"Cardiac resynchronization therapy" - news · newspapers · books · scholar · JSTOR (August 2016) (Learn how and when to remove ... "Cardiac Resynchronization Therapy and Implantable Cardioverter Defibrillator Therapy in Advanced Heart Failure". Heart Failure ... "Cardiac Resynchronization Therapy Technique: Approach Considerations, Placement of Pacing Leads, Programming of Device". ... Chest radiographs of cardiac resynchronization therapy with defibrillator (CRT-D) in an individual with dilated cardiomyopathy ...
... learn about Medtronics Cardiac Resynchronization Therapy, what to expect during CRT surgery, & other heart failure resources. ... Treatments & Therapies About Cardiac Resynchronization Devices Getting a Cardiac Resynchronization Therapy Device Questions and ... If your doctor has advised you that cardiac resynchronization therapy (CRT) may be the best course of treatment for your heart ... About Cardiac Resynchronization Therapy Devices * Living With a Cardiac Resynchronization Therapy Device ...
Known as the MADIT-CHIC study, it was the first of its kind to assess whether cardiac resynchronization therapy (CRT) could ... But six months after cardiac resynchronization therapy, Dennis and others in the study saw their EFs rise into the normal range ... Cardiac resynchronization therapy benefits cancer survivors with heart failure. University of Rochester Medical Center ... After six months with the implanted CRT devices, the 30 patients who received cardiac resynchronization therapy experienced ...
Echocardiography Guided Cardiac Resynchronization Therapy (EchoCRT) (EchoCRT). The safety and scientific validity of this study ... Cardiac Resynchronization Therapy activated.. Subject implanted with BIOTRONIK Lumax HF-T CRT-D system with ICD back-up enabled ... Cardiac-resynchronization therapy in heart failure with a narrow QRS complex. N Engl J Med. 2013 Oct 10;369(15):1395-405. doi: ... Cardiac Resynchronization Therapy deactivated.. Subject implanted with BIOTRONIK Lumax HF-T CRT-D system with ICD back-up ...
Echocardiography Guided Cardiac Resynchronization Therapy (EchoCRT). Official Title ICMJE Echocardiography Guided Cardiac ... Cardiac Resynchronization Therapy activated.. Intervention: Device: Implantable Cardioverter Defibrillator with Cardiac ... Cardiac Resynchronization Therapy deactivated.. Intervention: Device: Implantable Cardioverter Defibrillator with Cardiac ... Resynchronization Therapy (EchoCRT). Brief Summary The EchoCRT trial evaluates the effects of Cardiac Resynchronization Therapy ...
Treatments & Therapies About Cardiac Resynchronization Devices Questions and Answers - Cardiac Resynchronization Therapy ... If your doctor has advised you that cardiac resynchronization therapy may be the best course of treatment for your poorly ... Here are some common topics of interest to individuals considering an implantable cardiac resynchronization therapy device:. * ... What should I expect during cardiac resynchronization therapy (CRT) surgery?. Typically, the procedure to implant a heart ...
Cardiac Resynchronization Therapy Market by Product Type (Cardiac Resynchronization Therapy Defibrillator and Cardiac ... Resynchronization Therapy Pacemaker), End User (Hospitals & Cardiac Centers and Ambulatory Surgery Centers) - Global Forecast ... Cardiac Resynchronization Therapy Market by Product Type (Cardiac Resynchronization Therapy Defibrillator and Cardiac ... 6 Cardiac Resynchronization Therapy Market, By Type (Page No. - 38). 6.1 Introduction 6.2 Cardiac Resynchronization Therapy ...
A pacing system computes optimal cardiac resynchronization pacing parameters using intrinsic conduction intervals. In various ... 2. Cardiac Resynchronization Pacing Therapy. Cardiac resynchronization therapy is most conveniently delivered in conjunction ... Cardiac Pacemakers, Inc.. Morphology-based optimization of cardiac resynchronization therapy. US20060259086. May 11, 2005. Nov ... Cardiac Pacemakers, Inc.. Method and apparatus for predicting acute response to cardiac resynchronization therapy at a given ...
Cardiac Resynchronization Therapy (CRT). Call (718) 283-7315 for an appointment with an Advanced Heart Failure specialist or ... Cardiac resynchronization therapy (CRT) may be needed to improve heart function, reduce hospitalization risk, and improve ...
Request Report MethodologyGlobal Cardiac Resynchronization Therapy Systems Market: Scope and MethodologyThis report on the ... global Cardiac Resynchronization Therapy Systems Market analyzes the current and future prospects ... Cardiac Resynchronization Therapy Systems Market Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2017 - 2025 ... Cardiac Resynchronization Therapy Pacemaker. Cardiac Resynchronization Therapy Defibrillator. Global Cardiac Resynchronization ...
We offer the specialized expertise in cardiac resynchronization therapy (CRT), or biventricular pacing, to help relieve heart ... Cardiac resynchronization therapy. Cardiac resynchronization therapy (CRT) treats people with heart failure who have developed ... Our team of specialists collaborates every day to make sure we are combining therapies the right way, for the best results. ... Pacing expertise: CRT is an advanced pacing technique and requires expertise in several areas, including cardiology and cardiac ...
Modelling the economic and health consequences of cardiac resynchronization therapy in the UK.. Caro JJ1, Guo S, Ward A, Chalil ... Clinical evidence supports the use of cardiac resynchronization therapy (CRT) in advanced heart failure, but its cost- ... All inputs were obtained from the data collected in the CArdiac REsynchronization in Heart Failure (CARE-HF) trial and a ...
Risk Stratification and Benefits With Cardiac Resynchronization Therapy (CRT) (BENEFIT). The safety and scientific validity of ... Risk Stratification and Benefits With Cardiac Resynchronization Therapy Brief Summary This is an observational study to learn ... Risk Stratification and Benefits With Cardiac Resynchronization Therapy (CRT) Official Title ... Data from this study will be pooled with data from previous studies to build a more complete picture of CRT therapy. ...
This item: The Nuts and Bolts of Cardiac Resynchronization Therapy. Implantable Cardiac Pacemakers and Defibrillators: All You ... The Nuts and Bolts of Cardiac Resynchronization Therapy. By Tom Kenny, RN. Vice President, Clinical Education and Training, St ... The Nuts and Bolts of Cardiac Resynchronization Therapy concentrates on the practical aspects of how these devices work and how ... Cardiac resynchronization therapy (CRT) is an exciting new option for a growing number of heart failure patients, but CRT ...
As compared with optimal pharmacologic therapy alone, cardiac-resynchronization therapy with a pacemaker decreased the risk of ... Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure.. Bristow MR1 ... Cardiac resynchronization therapy reduced all-cause death and hospitalization in chronic heart failure. [ACP J Club. 2004] ... We tested the hypothesis that prophylactic cardiac-resynchronization therapy in the form of biventricular stimulation with a ...
When used in combination with optimal medical therapy, cardiac resynchronization therapy (CRT) is associated with a 50% ... Use of Cardiac Resynchronization Therapy in Patients Hospitalized With Heart Failure. Jonathan P. Piccini, Adrian F. Hernandez ... for the Cardiac Resynchronization-Heart Failure Study I. The effect of cardiac resynchronization on morbidity and mortality in ... Use of Cardiac Resynchronization Therapy in Patients Hospitalized With Heart Failure. Jonathan P. Piccini, Adrian F. Hernandez ...
Rationale Multiple clinical trials support the effectiveness of cardiac resynchronization therapy (CRT); however, optimal ...
Cleveland Clinic Cardiac Resynchronization Therapy-Heart Failure Follow-Up Clinic carefully evaluates patients with heart ... Cardiac Resynchronization Therapy-Heart Failure Follow-Up Clinic Cardiac Resynchronization Therapy-Heart Failure Follow-Up ... and a complete medical evaluation by both a cardiac electrophysiologist and a congestive heart failure specialist. Your plan of ... and if there is a possibility to further improve your cardiac medications or device settings. ...
A CRT-D is an implantable cardiac resynchronization therapy (CRT) defibrillator for patients with heart failure. The device ... Cardiac resynchronization therapy significantly lowers the risk of life-threatening cardiac events. Many patients quality of ... A CRT-P is a cardiac resynchronization therapy pacemaker that does not have the defibrillation capabilities of a CRT-D. CRT-Ds ... A CRT-D is an implantable cardiac resynchronization therapy (CRT) defibrillator for patients with heart failure. The device ...
Read our Heart Failure: Should I Get a Pacemaker (Cardiac Resynchronization Therapy)? encyclopedia resources online. ... Cardiac resynchronization therapy (CRT) uses a special type of pacemaker called a biventricular pacemaker (say "by-ven-TRICK- ... Cardiac resynchronization therapy (CRT) uses a special type of pacemaker called a biventricular pacemaker (say "by-ven-TRICK- ... A pacemaker for heart failure, also called cardiac resynchronization therapy or CRT, can help you feel better so you can do ...
Cardiac resynchronization therapy (CRT) uses a special type of pacemaker called a biventricular pacemaker (say "by-ven-TRICK- ... Cardiac resynchronization therapy (CRT) uses a special type of pacemaker called a biventricular pacemaker (say "by-ven-TRICK- ... Heart Failure: Should I Get a Pacemaker (Cardiac Resynchronization Therapy)?. Heres a record of your answers. You can use it ... A pacemaker for heart failure, also called cardiac resynchronization therapy or CRT, can help you feel better so you can do ...
I. Cardiac Resynchronization Therapy: What every physician needs to know.. Cardiac resynchronization therapy (CRT), also known ... "Cardiac-resynchronization therapy for the prevention of heart-failure events". N Engl J Med. vol. 361. 2009. pp. 1329-38. ... "Cardiac-resynchronization therapy in heart failure with narrow QRS complexes". N Engl J Med. vol. 357. 2007. pp. 2461-71. ... I. Cardiac Resynchronization Therapy: What every physician needs to know. * II. Diagnostic Confirmation: Are you sure your ...
An Issue of Cardiac Electrophysiology Clinics, Volume 7-4 - 1st Edition. Print Book & E-Book. ISBN 9780323402385, 9780323402392 ... Purchase Cardiac Resynchronization Therapy: State of the Art, ... Cardiac Resynchronization Therapy: State of the Art, An Issue ... Cardiac Resynchronization Therapy: State of the Art, An Issue of Cardiac Electrophysiology Clinics, Volume 7-4 1st Edition. ... The latest developments in the field of Cardiac Resynchronization Therapy are featured in this issue of Cardiac ...
"Cardiac Resynchronization Therapy Devices" by people in Profiles.. * Cardiac Resynchronization Therapy for Chemotherapy-Induced ... The European Society of Cardiology Cardiac Resynchronization Therapy Survey II: A comparison of cardiac resynchronization ... "Cardiac Resynchronization Therapy Devices" by people in Harvard Catalyst Profiles by year, and whether "Cardiac ... "Cardiac Resynchronization Therapy Devices" is a descriptor in the National Library of Medicines controlled vocabulary ...
Every effort should be made to reduce native atrioventricular conduction with cardiac resynchronization therapy systems in an ... Cardiac resynchronization therapy and the relationship of percent biventricular pacing to symptoms and survival Heart Rhythm. ... Background: With the advent of cardiac resynchronization therapy, it was unclear what percentage of biventricular pacing would ... Conclusion: Every effort should be made to reduce native atrioventricular conduction with cardiac resynchronization therapy ...
  • Cardiac resynchronization therapy (CRT), also known as biventricular pacing or multisite ventricular pacing, involves simultaneous pacing of the right ventricle (RV) and the left ventricle (LV). (medscape.com)
  • Cardiac pacing can be either temporary or permanent. (medscape.com)
  • CRT is a specialized type of pacemaker therapy that provides biventricular pacing. (medscape.com)
  • A pacing system computes optimal cardiac resynchronization pacing parameters using intrinsic conduction intervals. (google.com)
  • Cardiac resynchronization therapy pacemaker (CRT-P) also known as bi ventricular pacing is an implantable cardiac resynchronization therapy (CRT) pacemaker for patients with heart failure. (bccresearch.com)
  • CRT is an advanced pacing technique and requires expertise in several areas, including cardiology and cardiac electrophysiology. (geisinger.org)
  • Thomas P. Kenny, author of The Nuts & Bolts of Cardiac Pacing and T he Nuts and Bolts of ICDs , is the author on this book. (wiley.com)
  • Cardiac resynchronization therapy (CRT), also known as biventricular (biV) pacing, is an important component of the total management of patients with heart failure and a wide QRS complex on an electrocardiogram (EKG). (clinicaladvisor.com)
  • Cerclage parahisian septal pacing through the septal perforator branch of the great cardiac vein: Bedside-to-bench development of a novel technique and lead. (harvard.edu)
  • With the advent of cardiac resynchronization therapy, it was unclear what percentage of biventricular pacing would be required to obtain maximal symptomatic and mortality benefit from the therapy. (nih.gov)
  • Every effort should be made to reduce native atrioventricular conduction with cardiac resynchronization therapy systems in an attempt to achieve biventricular pacing as close to 100% as possible. (nih.gov)
  • Cardiac Resynchronization Therapy (CRT), also referred to as biventricular pacing, is often recommended for patients with severe heart dysfunction and congestive heart failure (CHF). (hackensackumc.org)
  • Offers AcuShock™ Advanced Technology, multiple programmable options to reduce inappropriate and unnecessary shocks, including a choice of rhythm discriminators, RhythmID™ with RhythmMatch™ (customization of Rhythm ID algorithm), antitachycardia pacing (ATP) therapy in all rates zones, and advanced sensing and filtering. (bostonscientific.com)
  • SafetyCore™ technology is intended to provide lifesaving shock therapy and basic pacing functionality in the event of an unrecoverable fault. (bostonscientific.com)
  • Significance: The fast CRT pacing predictions are a step forward to a non-invasive CRT patient selection and therapy optimisation, to help clinicians in these difficult tasks. (archives-ouvertes.fr)
  • These findings confirm what some clinicians and researchers have hypothesized for some time -- that heart failure patients with heart block do better when both sides of the heart are resynchronized, called biventricular pacing, using a cardiac resynchronization therapy (CRT) device," she says. (buffalo.edu)
  • Researchers and clinicians have hypothesized that better outcomes might result from pacing both the left and right ventricles of the heart, called biventricular pacing, which involves implanting a cardiac resynchronization therapy device. (buffalo.edu)
  • She also is author of a book on cardiac pacing. (buffalo.edu)
  • The effect of cardiac resynchronization therapy on antitachycardia pacing still has to be determined. (revespcardiol.org)
  • We compared antitachycardia pacing efficacy in patients with or without cardiac resynchronization therapy. (revespcardiol.org)
  • During follow-up, 32 patients received antitachycardia pacing: 15 with cardiac resynchronization therapy and 17 without. (revespcardiol.org)
  • In the 15 patients receiving resynchronization, 221 episodes of tachycardia were treated by antitachycardia pacing. (revespcardiol.org)
  • Methods and Results- Adult dogs underwent left bundle branch ablation and right atrial pacing at 200 bpm for either 6 weeks (dyssynchronous heart failure, n=12) or 3 weeks, followed by 3 weeks of resynchronization by biventricular pacing at the same pacing rate (CRT, n=10). (scialert.net)
  • Cardiac resynchronization therapy: an established pacing therapy for heart failure and mechanical dyssynchrony provides basic knowledge about congestive heart failure and also covers the evolution of cardiac resynchronization therapy. (eurekaselect.com)
  • Cardiac resynchronization therapy (CRT) using biventricular pacing is a relatively new treatment modality designed to restore synchrony with the objective to improve cardiac mechanical performance in congestive heart failure 1 - 4 . (pubmedcentralcanada.ca)
  • Little is known about the optimal right ventricular (RV) pacing site in cardiac resynchronization therapy (CRT). (ovid.com)
  • RePub, Erasmus University Repository: The 'Happy Ending Problem' of cardiac pacing? (eur.nl)
  • The 'Happy Ending Problem' of cardiac pacing? (eur.nl)
  • 2013 ESC guidelines on cardiac pacing and cardiac resynchronization therapy: the task force on cardiac pacing and resynchronization therapy of the European Society of Cardiology (ESC). (springermedizin.de)
  • A randomized double-blind comparison of biventricular versus left ventricular stimulation for cardiac resynchronization therapy: the Biventricular versus Left Univentricular Pacing with ICD Back-up in Heart Failure Patients (B-LEFT HF) trial. (springermedizin.de)
  • CRT with pacemaker only is often termed "CRT-P" to help distinguish it from CRT with defibrillator (CRT-D). The key indication for CRT is left bundle branch block (LBBB) of the heart, a cardiac abnormality leading to delayed left ventricular contraction. (wikipedia.org)
  • Chest radiographs of cardiac resynchronization therapy with defibrillator (CRT-D) in an individual with dilated cardiomyopathy after mitral valve replacement (MVR). (wikipedia.org)
  • Depending on the product type the global Cardiac Resynchronization Therapy Systems Market includes - Cardiac Resynchronization Therapy Pacemaker and Cardiac Resynchronization Therapy Defibrillator. (bccresearch.com)
  • Cardiac resynchronization therapy defibrillator (CRT-D) is implanted in heart failure patients who are at a high risk of sudden cardiac arrest. (bccresearch.com)
  • Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure. (nih.gov)
  • We tested the hypothesis that prophylactic cardiac-resynchronization therapy in the form of biventricular stimulation with a pacemaker with or without a defibrillator would reduce the risk of death and hospitalization among patients with advanced chronic heart failure and intraventricular conduction delays. (nih.gov)
  • In patients with advanced heart failure and a prolonged QRS interval, cardiac-resynchronization therapy decreases the combined risk of death from any cause or first hospitalization and, when combined with an implantable defibrillator, significantly reduces mortality. (nih.gov)
  • A CRT-D is an implantable cardiac resynchronization therapy (CRT) defibrillator for patients with heart failure . (biotronik.com)
  • Like an implantable defibrillator (ICD), a CRT-D is designed to stop life-threatening ventricular tachycardia and fibrillation with relatively weak and painless stimulation therapy or electrical shocks. (biotronik.com)
  • Cardiac implantable electronic devices with a defibrillator component and all-cause mortality in left ventricular assist device carriers: results from the PCHF-VAD registry. (harvard.edu)
  • Considering the product type the global Cardiac Resynchronization Therapy Systems Market is classified in to major segments- Cardiac Resynchronization Therapy Pacemaker and Cardiac Resynchronization Therapy Defibrillator. (transparencymarketresearch.com)
  • In 2016 cardiac resynchronization therapy defibrillator accounted for the major market share in terms of revenue. (transparencymarketresearch.com)
  • In North America and Europe the cardiac resynchronization therapy defibrillator segment of cardiac resynchronization therapy systems market contributes the maximum share. (transparencymarketresearch.com)
  • In the IN-TIME trial, automatic daily implant-based multiparameter telemonitoring significantly improved clinical outcomes in patients with chronic systolic heart failure and implantable cardioverter-defibrillator (ICD) or cardiac resynchronization therapy defibrillator (CRT-D). We compared IN-TIME results for ICD and CRT-D subgroups. (springer.com)
  • BARCELONA, Spain 5 September 2006 According to data presented today at the 2006 European Society of Cardiology (ESC)/World Congress of Cardiology (WCC), long-term treatment with Cardiac Resynchronisation Therapy (CRT) or CRT-D (with an implantable cardioverter defibrillator or ICD) is a cost-effective way to improve survival in patients with heart failure. (webwire.com)
  • Successful Treatment of an Infant with Left Ventricular Noncompaction Presenting with Fatal Ventricular Arrhythmia Treated with Cardiac Resynchronization Therapy and an Implantable Cardioverter Defibrillator. (thefreelibrary.com)
  • Arthur J. Moss discusses his research group's study of long-term survival for patients who received cardiac resynchronization therapy with a defibrillator in the MADIT-CRT trial. (jwatch.org)
  • Methods From the National Cardiovascular Data Registry's Implantable Cardiac-Defibrillator Registry, we defined a cohort of 45,392 cardiac resynchronization therapy-defibrillator (CRT-D) implants between January 2006 and June 2008 with a primary prevention indication. (onlinejacc.org)
  • Adoption of CRT has been rapid: cardiac resynchronization therapy-defibrillator (CRT-D) systems recently comprised 40% of all implantable cardiac-defibrillator (ICD) implants in the U.S. ( 8 ). (onlinejacc.org)
  • Our aim was to investigate the relationship between positive TPaVR and mortality in patients with cardiac resynchronization therapy defibrillator (CRT-D). (springermedizin.de)
  • Long-Term Echocardiographic Outcome in Super-Responders to Cardiac Resynchronization Therapy and the Association With Mortality and Defibrillator Therapy. (semanticscholar.org)
  • Effectiveness of Cardiac Resynchronization Therapy by QRS Morphology in the Multicenter Automatic Defibrillator Implantation Trial-Cardiac Resynchronization Therapy (MADIT-CRT). (semanticscholar.org)
  • Background: A recent study has demonstrated that mechanical discoordination, as estimated from internal stretch fraction (ISF), is a better predictor of reverse remodeling after cardiac resynchronization therapy (CRT) than mechanical dyssynchrony. (ahajournals.org)
  • Cardiac resynchronization therapy pacemakers (CRT-Ps) are implanted in patients to help treat cardiac conditions stemming from problems with the heart's electrical conduction system-particularly treatment of ventricular dyssynchrony. (ecri.org)
  • INTRODUCTION: The PROSPECT trial reported no single echocardiographic measurement of dyssynchrony is recommended to improve patient selection for cardiac resynchronization therapy (CRT). (biomedsearch.com)
  • CRT therapy works in about 7 out of 10 people who have heart failure and mismatching (dyssynchrony) of their heartbeat. (brighamandwomens.org)
  • Results: We evaluated our method on a dataset composed of 20 dyssynchrony patients with a total of 120 different cardiac cycles. (archives-ouvertes.fr)
  • Background- Cardiac electromechanical dyssynchrony causes regional disparities in workload, oxygen consumption, and myocardial perfusion within the left ventricle. (scialert.net)
  • We hypothesized that such dyssynchrony also induces region-specific alterations in the myocardial transcriptome that are corrected by cardiac resynchronization therapy (CRT). (scialert.net)
  • Conclusions- Our results demonstrate a profound effect of electromechanical dyssynchrony on the regional cardiac transcriptome, causing gene expression changes primarily in the anterior LV wall. (scialert.net)
  • Cardiac Resynchronization Therapy (CRT) is a treatment option for heart failure patients with ventricular dyssynchrony. (gatech.edu)
  • CRT corrects for dyssynchrony by electrically stimulating the septal and lateral walls of the left ventricle (LV), forcing synchronous con- traction and improving cardiac output. (gatech.edu)
  • Biomarkers that predict response to cardiac resynchronization therapy (CRT) in heart failure patients with dyssynchrony (HFDYS) would be clinically important. (readbyqxmd.com)
  • Cardiac resynchronization therapy (CRT) is an emerging option for treating dyssynchrony-associated heart failure in patients with pediatric or congenital heart disease. (radcliffecardiology.com)
  • Cardiac resynchronization reduces symptoms and improves left ventricular function in many patients with heart failure due to left ventricular systolic dysfunction and cardiac dyssynchrony. (scienceopen.com)
  • Patients with New York Heart Association class III or IV heart failure due to left ventricular systolic dysfunction and cardiac dyssynchrony who were receiving standard pharmacologic therapy were randomly assigned to receive medical therapy alone or with cardiac resynchronization. (scienceopen.com)
  • In patients with heart failure and cardiac dyssynchrony, cardiac resynchronization improves symptoms and the quality of life and reduces complications and the risk of death. (scienceopen.com)
  • Effect of cardiac resynchronization therapy in patients without left intraventricular dyssynchrony. (semanticscholar.org)
  • AIMS To evaluate the effects of cardiac resynchronization therapy (CRT) on long-term survival of patients without baseline left ventricular (LV) mechanical dyssynchrony. (semanticscholar.org)
  • Cellular and Molecular Aspects of Dyssynchrony and Resynchronization. (semanticscholar.org)
  • Relationship of echocardiographic dyssynchrony to long-term survival after cardiac resynchronization therapy. (semanticscholar.org)
  • A new device, called the Shape-HF Cardiopulmonary Testing System, cleared by FDA in April, optimizes heart failure therapy for people using pacemakers. (dotmed.com)
  • On the basis of product type, the global market is segmented into cardiac resynchronization therapy Defibrillators (CRT-Ds) and cardiac resynchronization therapy Pacemakers (CRT-Ps). (marketsandmarkets.com)
  • In 2017, the company received the US FDA approval for its quadripolar cardiac resynchronization therapy pacemakers (CRT-Ps), which improve therapy delivery for patients with heart failure. (marketsandmarkets.com)
  • In 2017, the company also received the CE mark approval for a suite of quadripolar cardiac resynchronization therapy pacemakers (CRT-Ps). (marketsandmarkets.com)
  • Cardiac Pacemakers, Inc. (google.com)
  • Cardiac resynchronization therapy (CRT) is an exciting new option for a growing number of heart failure patients, but CRT systems present special challenges to clinicians, even those accustomed to working with pacemakers. (wiley.com)
  • Computed Tomography-Guided Assessment of Response to Cardiac Resynchronization Therapy. (harvard.edu)
  • A new baseline scoring system may help to predict response to cardiac resynchronization therapy. (biomedsearch.com)
  • Does Permanent Atrial Fibrillation Modify Response to Cardiac Resynchronization. (rcaap.pt)
  • In this updated critical appraisal we report on the main miRs that play a key role in response to cardiac resynchronization therapy (i.e., responder vs nonresponder HF patients), focusing on the miR-mediated modulation of cardiac angiogenesis, apoptosis, fibrosis and membrane ionic currents. (elsevier.com)
  • When right may not be right: right bundle-branch block and response to cardiac resynchronization therapy. (semanticscholar.org)
  • Cardiac resynchronization therapy (CRT) treats people with heart failure who have developed arrhythmias, or irregular heart beats. (geisinger.org)
  • The European Society of Cardiology Cardiac Resynchronization Therapy Survey II: A comparison of cardiac resynchronization therapy implantation practice in Europe and France. (medworm.com)
  • Written by noted experts with day-to-day experience in cardiac resynchronization therapy (CRT), this comprehensive, practical reference gives physicians a thorough knowledge of the indications, techniques for implantation, complications, programming, and follow-up of CRT devices in patients with heart failure and intra- and interventricular conduction delays. (alibris.com)
  • Cardiac resynchronization therapy involves the implantation of a pacemaker-type device that delivers small electric shocks to both ventricles of the heart in order to coordinate, or "synchronize," their function and ensure their optimal performance. (jarvikheart.com)
  • Although sex disparities are also remarkable in the accessibility to HF device therapy, including cardiac resynchronization therapy (CRT) ( 7 - 9 ), women are more likely to respond favorably and derive a greater survival benefit from CRT implantation ( 10 - 13 ). (frontiersin.org)
  • In patients with significant left ventricular dysfunction and congestive heart failure despite optimal medical therapy, implantation of cardiac resynchronization therapy-defibrillation (CRT-D) devices has been shown to improve symptoms and mortality. (ovid.com)
  • Further, the Cardiac Resynchronization Therapy Pacemaker report states that there is a high risk of potential complications in the implantation of CRT-Ps. (sbwire.com)
  • 2008). Prognostic value of electrocardiographic measurements before and after cardiac resynchronization device implantation in patients with heart failure due to ischemic or nonischemic cardiomyopathy. (springer.com)
  • New sections on cardiac anatomy and physiology and imaging of the heart, a new online chapter covering radiography of devices, and thought-provoking new information on the basic science of device implantation. (iberlibro.com)
  • The implantation of a cardiac-resynchronization device should routinely be considered in such patients. (scienceopen.com)
  • A pacemaker for heart failure is used for cardiac resynchronization therapy (CRT). (northshore.org)
  • A pacemaker for heart failure, also called cardiac resynchronization therapy or CRT, can help you feel better so you can do your daily activities. (northshore.org)
  • Modelling the economic and health consequences of cardiac resynchronization therapy in the UK. (nih.gov)
  • The global cardiac resynchronization therapy systems market was valued approximately US$ 3.1 Bn in 2016 and is anticipated to register CAGR of over 5.3% from 2017 to 2025 to reach value of approximately US$ 4.8 Bn by 2025. (transparencymarketresearch.com)
  • Global Cardiac Resynchronization Therapy Device Market Professional Survey Report 2017" Purchase This Report by calling ResearchnReports.com at +1-888-631-6977. (medgadget.com)
  • Pune, Maharashtra -- ( SBWIRE ) -- 02/08/2017 -- Cardiac Resynchronization Therapy Pacemaker Market , has been prepared based on an in-depth market analysis with inputs from industry experts. (sbwire.com)
  • Abstract Background: Cardiac resynchronization therapy (CRT) is effective, but only 60-70% of patients benefit from the therapy. (lu.se)
  • An abstract of the study "Dilated Cardiomyopathy: Alternative Treatment With Resynchronization Cardiac and Stem Cells Therapy: Preliminary Results," by O. T. Greco and colleagues is presented. (ebscohost.com)
  • abstract = "Heart failure (HF) disease progression is related to numerous adaptive processes including cardiac fibrosis, hypertrophy and apoptosis by activation of the 'fetal' gene program and downregulation of mRNA signatures, suggesting the importance of molecular mechanisms that suppress mRNA steady-state levels. (elsevier.com)
  • The ACC Foundation (ACCF) and Heart Rhythm Society (HRS), along with key specialty societies, on Feb. 28 released appropriate use criteria (AUC) for implantable cardioverter-defibrillators (ICDs) and cardiac resynchronization therapy (CRT) . (acc.org)
  • The authors of this week's paper used single molecule localization super resolution microscopy to study the effect of cardiac failure on the sarcomeric cytoskeleton after cardiac failure. (bruker.com)
  • Objectives: We evaluated the short-term effect of cardiac resynchronization therapy (CRT) on sleep apnea in patients with systolic heart failure. (elsevier.com)
  • Thus, for younger patients with heart failure who do not have serious non-cardiac co-morbidity such as respiratory disease, cancer or end-stage renal failure, CRT-D may be the best choice. (webwire.com)
  • Cardiac resynchronization therapy (CRT) reduces morbidity and mortality in patients with advanced symptoms of heart failure. (annals.org)
  • The efficacy of cardiac resynchronization therapy (CRT) has been demonstrated with significant reductions in mortality and morbidity of heart failure patients. (healthcanal.com)
  • 2009). Surface electrocardiogram to predict outcome in candidates for cardiac resynchronization therapy: a sub-analysis of the CARE-HF trial. (springer.com)
  • 2004) Potential candidates for cardiac resynchronization therapy in Japanese patients with idiopathic dilated cardiomyopathy a Niigatamulticenter study of DCM. (hanspub.org)
  • AIMS: Various strain parameters and multiple imaging techniques are presently available including cardiovascular magnetic resonance (CMR) tagging (CMR-TAG), CMR feature tracking (CMR-FT), and speckle tracking echocardiography (STE). This study aims to compare predictive performance of different strain parameters and evaluate results per imaging technique to predict cardiac resynchronization therapy (CRT) response. (rug.nl)
  • A CRT-P is a cardiac resynchronization therapy pacemaker that does not have the defibrillation capabilities of a CRT-D. CRT-Ds enhance diseased hearts' effectiveness and increase blood flow. (biotronik.com)
  • Known as the MADIT-CHIC study, it was the first of its kind to assess whether cardiac resynchronization therapy (CRT) could improve heart function in patients with congestive heart failure and cardiomyopathy, an enlargement of the heart due to chemotherapy side effects. (eurekalert.org)
  • As part of this comprehensive evaluation you will undergo an echocardiogram, functional testing with a nurse, and a complete medical evaluation by both a cardiac electrophysiologist and a congestive heart failure specialist. (clevelandclinic.org)
  • Due to use of cardiac resynchronization therapy for treatment of heart failure patients, there are lower number of deaths occurring as a result of sudden cardiac arrest in heart failure patients. (transparencymarketresearch.com)
  • BUFFALO, N.Y. -- Heart failure patients with a condition called "heart block" derive significant benefit from cardiac resynchronization therapy (CRT), according to the results of the Block HF clinical trial, presented today at the American Heart Association Scientific Sessions 2012 meeting in Los Angeles. (buffalo.edu)
  • Boback Ziaeian discusses his observational study exploring the benefits of guideline-recommended cardiac resynchronization therapy and ICD therapy in heart failure patients, according to race and ethnicity. (jwatch.org)
  • Severe FMR is common in heart failure patients, including approximately one-third of those indicated for CRT therapy. (healthcanal.com)
  • Anemia and its association with clinical outcome in heart failure patients undergoing cardiac resynchronization therapy. (lu.se)
  • Randomized trial of cardiac resynchronization in mildly symptomatic heart failure patients and in asymptomatic patients with left ventricular dysfunction and previous heart failure symptoms. (springer.com)
  • Circulating microRNA changes in heart failure patients treated with cardiac resynchronization therapy: responders vs. non-responders. (readbyqxmd.com)
  • We carried out this study to investigate mid-term effects of cardiac resynchronization therapy (CRT) on right ventricular (RV) function and neurohormonal response, expressed by N-terminal pro-brain natriuretic peptide (NT-proBNP), in heart failure patients stratified by baseline RV ejection fraction (RVEF). (springermedizin.de)
  • The present invention relates generally to cardiac resynchronization therapy (CRT), and more specifically, to methods and systems for optimization of CRT parameters. (google.com)
  • Background- The frequency and characterization of patients receiving cardiac resynchronization therapy (CRT) are largely unknown since the publication of pivotal clinical trials and subsequent incorporation of CRT into the American College of Cardiology/American Heart Association guidelines for heart failure. (ahajournals.org)
  • All inputs were obtained from the data collected in the CArdiac REsynchronization in Heart Failure (CARE-HF) trial and a hospital in the UK. (nih.gov)
  • 2009). Prevention of disease progression by cardiac resynchronization therapy in patients with asymptomatic or mildly symptomatic left ventricular dysfunction: insights from the European cohort of the REVERSE (Resynchronization Reverses Remodeling in Systolic Left Ventricular Dysfunction) trial. (springer.com)
  • It was introduced in the 1990s and revolutionized therapy for many patients with persistent symptoms of systolic HF. (medscape.com)
  • Studies show that Cardiac Resynchronization Therapy (CRT) can diminish symptoms such as shortness of breath, and improve exercise endurance and overall quality of life. (hackensackumc.org)
  • Left ventricular noncompaction (LVNC) is a rare congenital cardiomyopathy with a clinical presentation that ranges from no symptoms to sudden cardiac death due to fatal arrhythmia or heart failure. (thefreelibrary.com)
  • Cardiac resynchronization therapy improves HF symptoms, exercise capacity, and left ventricular (LV) function. (eur.nl)
  • Randomized trials have shown that cardiac resynchronization therapy (CRT) in carefully selected patients leads to improved cardiac function, symptoms, quality of life, and survival ( 1-4 ). (onlinejacc.org)
  • The latest developments in the field of Cardiac Resynchronization Therapy are featured in this issue of Cardiac Electrophysiology Clinics. (elsevier.com)
  • Recent studies suggest that baseline prolonged PR interval is associated with worse outcome in cardiac resynchronization therapy (CRT). (cardiol.br)
  • Electrocardiographic outcome of resynchronization therapy. (semanticscholar.org)
  • The author and his team have made a tremendous effort to keep this book up to date in the rapidly evolving field of implantable cardiac devices. (iberlibro.com)
  • The Shape-HF system helps physicians quantify shortness of breath, measure patient response to therapy, define patient functional classification, track patient progress, and predict the patient's hospitalization risk," Clarence Johnson, Shape-HF's president (St Paul, MN), tells DOTmed News. (dotmed.com)
  • Chronic sildenafil lowers transpulmonary gradient and improves cardiac output allowing successful he. (biomedsearch.com)
  • Cardiac resynchronization therapy improves cardiac performance and myocardial mechanical efficiency. (elsevier.com)
  • To explore possible associations that may explain the greater benefit from cardiac resynchronization therapy (CRT) reported amongst women. (nih.gov)
  • Cardiac resynchronisation therapy (CRT or CRT-P) is the insertion of electrodes in the left and right ventricles of the heart, as well as on occasion the right atrium, to treat heart failure by coordinating the function of the left and right ventricles via a pacemaker, a small device inserted into the interior chest wall. (wikipedia.org)
  • Medtronic is a medical technology company that manufactures, designs, develops, and markets a wide range of solutions and medical devices used in the treatment of cardiac, spinal, neurological, vascular, and chronic conditions. (marketsandmarkets.com)
  • Cardiac resynchronization therapy reduced all-cause death and hospitalization in chronic heart failure. (nih.gov)
  • 2002). Cardiac resynchronization in chronic heart failure. (springer.com)
  • Thirty-three patients (32 males) with chronic heart failure, NYHA class III-IV, optimal drug therapy, QRS-duration ≥150 ms, and chronic atrial fibrillation (AF) received CRT with two different RV leads, in the apex (RVA) or outflow tract (RVOT), together with an LV lead, all connected to a bi-ventricular pacemaker. (ovid.com)
  • CRT has proved beneficial for both the acute manipulation of cardiac output after surgery for congenital heart defects and for the management of chronic systemic ventricular failure. (radcliffecardiology.com)
  • Electromechanical effects of cardiac resynchronization therapy during rest and stress in patients with heart failure. (biomedsearch.com)
  • On average treating patients with heart failure costs 1 to 2 percent of the healthcare budget of developed countries, stated Peter Steinmann, vice president for the Medtronic Cardiac Rhythm Disease Management business in Western Europe. (webwire.com)
  • To assess the prevalence of indication for cardiac resynchronization therapy (CRT) in patients with heart failure (HF) and reduced ejection fraction (EF) when recommendations from evolving European Society of Cardiology (ESC) guidelines are considered. (diva-portal.org)
  • The incidence of these diseases is rising, with sudden cardiac arrest being the leading cause of death worldwide among people aged above 40. (sbwire.com)
  • Patients with non-ischaemic dilated cardiomyopathy and hyper-responders to cardiac resynchronization therapy: characteristics and long-term evolution. (springer.com)
  • When used in combination with optimal medical therapy, cardiac resynchronization therapy (CRT) is associated with a 50% reduction in hospitalization for HF and a 36% reduction in mortality. (ahajournals.org)
  • Methods: 211 patients on optimal medical therapy were included retrospectively (72 ± 10 yrs., 66% LBBB, 48% DCMP, 80% male) and investigated at baseline and 6 months later. (lu.se)
  • The article presents abstracts on topics related to cells which include mesenchymal stem cell therapy, genetic modifiers in Betta-Thalassemia, and investigation of matrix metaloproteinase-2 levels as effective factor in acute myocardial infarction. (ebscohost.com)
  • Design and rationale for the Stimulation Of the Left Ventricular Endocardium for Cardiac Resynchronization Therapy in non-responders and previously untreatable patients (SOLVE-CRT) trial. (harvard.edu)
  • Timing of atrial, right (RV), and left ventricular (LV) stimulation in cardiac resynchronization therapy (CRT) is known to affect electrical activation and pump function of the LV. (frontiersin.org)
  • 6. The system of claim 1 , wherein coefficients of the linear function and the intrinsic conduction parameter are derived from a linear regression analysis of clinical population data relating different values of the intrinsic conduction parameter to an optimum AVD interval for delivering cardiac resynchronization therapy as determined by measurement of a cardiac function parameter. (google.com)
  • They are used to treat various cardiac conduction disturbances which interfere with the timing of contraction of the ventricles. (harvard.edu)
  • 2012). QRS prolongation induced by cardiac resynchronization therapy correlates with deterioration in left ventricular function. (springer.com)
  • In fact, this book evolves from his many years teaching device therapy to clinicians. (wiley.com)
  • Evaluation, Management, and Outcomes of Patients Poorly Responsive to Cardiac Resynchronization Device Therapy. (harvard.edu)
  • Her research interests include clinical trials in implantable device therapy for prevention of sudden cardiac death and management of heart failure, as well as clinical trials in atrial fibrillation. (buffalo.edu)
  • Exercise training is a well-established therapy for heart failure (HF) patients recommended in the European Society of Cardiology (ESC) HF guidelines [1]. (medworm.com)
  • 1,2 To address these poor outcomes, improved use of existing HF therapies and new treatments for HF have been sought. (ahajournals.org)
  • The relative importance of variables explaining sex-related differences in outcomes is scarcely explored in patients undergoing cardiac resynchronization therapy (CRT). (frontiersin.org)
  • The European Cardiac Resynchronization Therapy Survey: comparison of outcomes between de novo cardiac resynchronization therapy implantations and upgrades. (springermedizin.de)
  • INTRODUCTION: The benefits of cardiac resynchronization therapy (CRT) documented in heart failure (HF) may be influenced by atrial fibrillation (AF). (rcaap.pt)
  • The comparison with a commercially available electrocardiographic imaging (ECGI) method shows a good identification of the cardiac activation pattern. (archives-ouvertes.fr)