A state of subnormal or depressed cardiac output at rest or during stress. It is a characteristic of CARDIOVASCULAR DISEASES, including congenital, valvular, rheumatic, hypertensive, coronary, and cardiomyopathic. The serious form of low cardiac output is characterized by marked reduction in STROKE VOLUME, and systemic vasoconstriction resulting in cold, pale, and sometimes cyanotic extremities.
Apparatus that provides mechanical circulatory support during open-heart surgery, by passing the heart to facilitate surgery on the organ. The basic function of the machine is to oxygenate the body's venous supply of blood and then pump it back into the arterial system. The machine also provides intracardiac suction, filtration, and temperature control. Some of the more important components of these machines include pumps, oxygenators, temperature regulators, and filters. (UMDNS, 1999)
Surgery performed on the heart.
Diversion of the flow of blood from the entrance of the right atrium directly to the aorta (or femoral artery) via an oxygenator thus bypassing both the heart and lungs.
The volume of BLOOD passing through the HEART per unit of time. It is usually expressed as liters (volume) per minute so as not to be confused with STROKE VOLUME (volume per beat).
Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
Compounds of the general formula R:N.NR2, as resulting from the action of hydrazines with aldehydes or ketones. (Grant & Hackh's Chemical Dictionary, 5th ed)
A state of elevated cardiac output due to conditions of either increased hemodynamic demand or reduced cardiac oxygen output. These conditions may include ANEMIA; ARTERIOVENOUS FISTULA; THYROTOXICOSIS; PREGNANCY; EXERCISE; FEVER; and ANOXIA. In time, compensatory changes of the heart can lead to pathological form of high cardiac output and eventual HEART FAILURE.
Messages between computer users via COMPUTER COMMUNICATION NETWORKS. This feature duplicates most of the features of paper mail, such as forwarding, multiple copies, and attachments of images and other file types, but with a speed advantage. The term also refers to an individual message sent in this way.
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
Devices for continuously measuring and displaying the arterial blood pressure.
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.
Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.
A noninvasive technique that uses the differential absorption properties of hemoglobin and myoglobin to evaluate tissue oxygenation and indirectly can measure regional hemodynamics and blood flow. Near-infrared light (NIR) can propagate through tissues and at particular wavelengths is differentially absorbed by oxygenated vs. deoxygenated forms of hemoglobin and myoglobin. Illumination of intact tissue with NIR allows qualitative assessment of changes in the tissue concentration of these molecules. The analysis is also used to determine body composition.
Solutions which, upon administration, will temporarily arrest cardiac activity. They are used in the performance of heart surgery.
An element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.
A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE).
A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
Disease having a short and relatively severe course.
A positive inotropic cardiotonic agent with vasodilator properties. It inhibits cAMP phosphodiesterase type 3 activity in myocardium and vascular smooth muscle. Milrinone is a derivative of amrinone and has 20-30 times the inotropic potency of amrinone.
A plant genus of the family Musaceae, order Zingiberales, subclass Zingiberidae, class Liliopsida.
One of the catecholamine NEUROTRANSMITTERS in the brain. It is derived from TYROSINE and is the precursor to NOREPINEPHRINE and EPINEPHRINE. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (RECEPTORS, DOPAMINE) mediate its action.
A subfamily of G-PROTEIN-COUPLED RECEPTORS that bind the neurotransmitter DOPAMINE and modulate its effects. D2-class receptor genes contain INTRONS, and the receptors inhibit ADENYLYL CYCLASES.
A subfamily of G-PROTEIN-COUPLED RECEPTORS that bind the neurotransmitter DOPAMINE and modulate its effects. D1-class receptor genes lack INTRONS, and the receptors stimulate ADENYLYL CYCLASES.
Drugs that bind to and activate dopamine receptors.
Drugs that bind to but do not activate DOPAMINE RECEPTORS, thereby blocking the actions of dopamine or exogenous agonists. Many drugs used in the treatment of psychotic disorders (ANTIPSYCHOTIC AGENTS) are dopamine antagonists, although their therapeutic effects may be due to long-term adjustments of the brain rather than to the acute effects of blocking dopamine receptors. Dopamine antagonists have been used for several other clinical purposes including as ANTIEMETICS, in the treatment of Tourette syndrome, and for hiccup. Dopamine receptor blockade is associated with NEUROLEPTIC MALIGNANT SYNDROME.
Cell-surface proteins that bind dopamine with high affinity and trigger intracellular changes influencing the behavior of cells.
Total or partial excision of the larynx.
Abnormal passage between the ESOPHAGUS and the TRACHEA, acquired or congenital, often associated with ESOPHAGEAL ATRESIA.
A device, activated electronically or by expired pulmonary air, which simulates laryngeal activity and enables a laryngectomized person to speak. Examples of the pneumatic mechanical device are the Tokyo and Van Hunen artificial larynges. Electronic devices include the Western Electric electrolarynx, Tait oral vibrator, Cooper-Rand electrolarynx and the Ticchioni pipe.
A method of speech used after laryngectomy, with sound produced by vibration of the column of air in the esophagus against the contracting cricopharyngeal sphincter. (Dorland, 27th ed)
Methods of enabling a patient without a larynx or with a non-functional larynx to produce voice or speech. The methods may be pneumatic or electronic.
The region of southwest Asia and northeastern Africa usually considered as extending from Libya on the west to Afghanistan on the east. (From Webster's New Geographical Dictionary, 1988)
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
A progressive condition usually characterized by combined failure of several organs such as the lungs, liver, kidney, along with some clotting mechanisms, usually postinjury or postoperative.
A disease or state in which death is possible or imminent.
Hospital units providing continuous surveillance and care to acutely ill patients.
Sequential operating programs and data which instruct the functioning of a digital computer.
Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.
NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
The hollow, muscular organ that maintains the circulation of the blood.

Regulation of sympathetic nerve activity in heart failure: a role for nitric oxide and angiotensin II. (1/847)

The mechanisms by which sympathetic function is augmented in chronic heart failure (CHF) are not well understood. A previous study from this laboratory (Circ Res. 1998;82:496-502) indicated that blockade of nitric oxide (NO) synthesis resulted in only an increase in renal sympathetic nerve activity (RSNA) when plasma angiotensin II (Ang II) levels were elevated. The present study was undertaken to determine if NO reduces RSNA in rabbits with CHF when Ang II receptors are blocked. Twenty-four New Zealand White rabbits were instrumented with cardiac dimension crystals, a left ventricular pacing lead, and a pacemaker. After pacing at 360 to 380 bpm for approximately 3 weeks, a renal sympathetic nerve electrode and arterial and venous catheters were implanted. Studies were carried out in the conscious state 3 to 7 days after electrode implantation. The effects of a 1-hour infusion of sodium nitroprusside (SNP; 3 microgram . kg-1. min-1) on RSNA and mean arterial pressure (MAP) were determined before and after Ang II blockade with losartan (5 mg/kg) in normal and CHF rabbits. Changes in MAP were readjusted to normal with phenylephrine. Before losartan, SNP evoked a decrease in MAP and an increase in RSNA in both groups that was baroreflex-mediated, because both MAP and RSNA returned to control when phenylephrine was administered. In the normal group, losartan plus SNP caused a reduction in MAP and an increase in RSNA that was 152.6+/-9.8% of control. Phenylephrine returned both MAP and RSNA back to the control levels. However, in the CHF group, losartan plus SNP evoked a smaller change in RSNA for equivalent changes in MAP (117.1+/-4.1% of control). On returning MAP to the control level with phenylephrine, RSNA was reduced to 65.2+/-2.9% of control (P<0. 0001). These data suggest that endogenous Ang II contributes to the sympathoexcitation in the CHF state and that blockade of Ang II receptors plus providing an exogenous source of NO reduces RSNA below the elevated baseline levels. We conclude that both a loss of NO and an increase in Ang II are necessary for sustained increases in sympathetic nerve activity in the CHF state.  (+info)

The sarcoplasmic reticulum and the Na+/Ca2+ exchanger both contribute to the Ca2+ transient of failing human ventricular myocytes. (2/847)

Our objective was to determine the respective roles of the sarcoplasmic reticulum (SR) and the Na+/Ca2+ exchanger in the small, slowly decaying Ca2+ transients of failing human ventricular myocytes. Left ventricular myocytes were isolated from explanted hearts of patients with severe heart failure (n=18). Cytosolic Ca2+, contraction, and action potentials were measured by using indo-1, edge detection, and patch pipettes, respectively. Selective inhibitors of SR Ca2+ transport (thapsigargin) and reverse-mode Na+/Ca2+ exchange activity (No. 7943, Kanebo Ltd) were used to define the respective contribution of these processes to the Ca2+ transient. Ca2+ transients and contractions induced by action potentials (AP transients) at 0.5 Hz exhibited phasic and tonic components. The duration of the tonic component was determined by the action potential duration. Ca2+ transients induced by caffeine (Caf transients) exhibited only a phasic component with a rapid rate of decay that was dependent on extracellular Na+. The SR Ca2+-ATPase inhibitor thapsigargin abolished the phasic component of the AP Ca2+ transient and of the Caf transient but had no significant effect on the tonic component of the AP transient. The Na+/Ca2+ exchange inhibitor No. 7943 eliminated the tonic component of the AP transient and reduced the magnitude of the phasic component. In failing human myocytes, Ca2+ transients and contractions exhibit an SR-related, phasic component and a slow, reverse-mode Na+/Ca2+ exchange-related tonic component. These findings suggest that Ca2+ influx via reverse-mode Na+/Ca2+ exchange during the action potential may contribute to the slow decay of the Ca2+ transient in failing human myocytes.  (+info)

Peripheral muscle ergoreceptors and ventilatory response during exercise recovery in heart failure. (3/847)

Recent studies have suggested that the increased ventilatory response during exercise in patients with chronic heart failure was related to the activation of muscle metaboreceptors. To address this issue, 23 patients with heart failure and 7 normal subjects performed arm and leg bicycle exercises with and without cuff inflation around the arms or the thighs during recovery. Obstruction slightly reduced ventilation and gas exchange variables at recovery but did not change the kinetics of recovery of these parameters compared with nonobstructed recovery: half-time of ventilation recovery was 175 +/- 54 to 176 +/- 40 s in patients and 155 +/- 66 to 127 +/- 13 s in controls (P < 0.05, patients vs. controls, not significant within each group from baseline to obstructed recovery). We conclude that muscle metaboreceptor activation does not seem to play a role in the exertion hyperventilation of patients with heart failure.  (+info)

High and low pulmonary vascular resistance in heart transplant candidates. A 5-year follow-up after heart transplantation shows continuous reduction in resistance and no difference in complication rate. (4/847)

BACKGROUND: In heart transplantation candidates, high pulmonary vascular resistance has been found to decrease promptly after heart transplantation without any further reduction during follow-up. Pulmonary hypertension has been described as associated with an increased peri- and postoperative complication rate and mortality. This study describes the evolution of pulmonary vascular resistance and the outcome for patients during 5 years following heart transplantation. METHODS AND RESULTS: Haemodynamic data, complication rate and mortality have been analysed during 5-year follow-up in all patients (n = 80) who were heart transplanted at Sahlgrenska University Hospital from 1988 through 1990. We found a significant and continuous reduction in pulmonary vascular resistance both in patients with a pre-operative high (> 3 Wood Units; n = 36), but reversible on nitroprusside, and pre-operative low (< or = 3 Wood Units; n = 44) pulmonary vascular resistance. A multivariate analysis showed that a pre-operative high mean pulmonary artery and low mean pulmonary capillary wedge pressure predicted the decline in pulmonary vascular resistance during 5 years after heart transplantation. The need for a postoperative assist device, complication rate, and early and late mortality were independent of the pre-operative level of pulmonary vascular resistance. CONCLUSIONS: A continuous reduction in pulmonary vascular resistance during 5 years following heart transplantation was found in patients with both high, but reversible, and low pre-operative resistance levels. The outcome and survival were independent of the pre-operative pulmonary vascular resistance level.  (+info)

Clinical practice guidelines for heart failure. (5/847)

Development of guidelines can be a difficult process; each organization or institution must establish the rules and criteria for including specific therapies and the level of complexity needed. Specific outcomes must be incorporated, including maintenance of comfort and functionality, freedom from hospitalization, and survival. In existing guidelines for the management of heart failure, angiotensin-converting enzyme (ACE) inhibitor therapy is clearly the gold standard. However, there is still a high mortality with ACE inhibitor therapy; the key may be choosing the right patients. Current guidelines reflect the uncertainty regarding digoxin before the Digitalis Investigation Group (DIG) trial; obviously, these guidelines should be revisited. Clinical practice guidelines for the management of heart failure need to be revised to include a better consensus on beta-blockade, the new data on digoxin, emerging data on angiotensin II receptor antagonists, and current thinking on anticoagulant therapy.  (+info)

Cost of heart failure to the healthcare system. (6/847)

From an economic, mortality, and functional standpoint, heart failure is clearly a disease that needs to be targeted. We can develop a model for heart failure to determine the impact that specific management strategies will have on the overall cost to the system, which by itself can tell us some interesting things because we're currently spending twice as much on transplantation as on digoxin therapy. We can then use this model to assess the impact of different strategies, such as greater use of angiotensin-converting enzyme (ACE) inhibitors or digoxin therapy.  (+info)

Heart failure and disease management. (7/847)

Disease management is a comprehensive program that identifies a population of patients at risk, provides a coherent framework of coordinated care for these patients, and demonstrates improved outcomes. In applying disease management strategies to heart failure, there is clearly the technology to improve outcomes. The two main issues involved are influencing physician practice patterns and improving patient compliance. A successful disease management program in heart failure should include patient identification patient assessment, patient education and training, patient monitoring, and triage and acute intervention. With the advances in treatment of heart failure, we have the means to keep patients out of the hospital, maintain their functionality, and decrease mortality. The real issue, which is where disease management can help, is how to apply technology in an effective way to turn potential gains into real gains. The key is not to develop more technology, but to implement effectively the technology that exists.  (+info)

Localization and quantitation of cardiac annexins II, V, and VI in hypertensive guinea pigs. (8/847)

Annexins are characterized by Ca2+-dependent binding to phospholipids. Annexin II mainly participates in cell-cell adhesion and signal transduction, whereas annexins V and VI also seem to regulate intracellular calcium cycling. Their abundance and localization were determined in left ventricle (LV) and right ventricle (RV) from hypertensive guinea pigs, during the transition from compensatory hypertrophy to heart failure. Immunoblot analysis of annexins II, V, and VI revealed an increased accumulation (2.6-, 1.45-, and 2.3-fold, respectively) in LV from hypertensive guinea pigs and no modification in RV. Immunofluorescent labeling of annexins II, V, and VI; of Na+-K+-ATPase; and of sarcomeric alpha-actinin showed that in control LV and RV, 1) annexin II is present in nonmuscle cells; 2) annexins V and VI are mainly observed in the sarcolemma and intercalated disks of myocytes; 3) annexins II, V, and VI strongly label endothelial cells and adventitia of coronary arteries; and 4) annexin VI is present in the media. At the onset of heart failure, the most striking changes are the increased protein accumulation in LV and the very strong labeling of annexins II, V, and VI in interstitial tissue, suggesting a role in fibrosis development and cardiac remodeling.  (+info)

This trial was designed as a randomized, double-blind, 2-arm, parallel-group, placebo-controlled study within thirteen participating cardiac surgical centers. Eligible patients included those with reduced left ventricular ejection fraction (40% or lower), undergoing CABG surgery with cardiopulmonary bypass alone or combined with valve surgery. Patients were assigned in 1:1 fashion to either levosimendan or placebo. Primary end point included a composite of 3 elements reflecting low cardiac output syndrome. These included catecholamine infusion persisting beyond 48 hours after infusion of levosimendan, need for left ventricular assist device in the post-operative period, or the need for renal replacement therapy during the intensive care unit stay. Secondary end-points included in-hospital mortality, number of days with mechanical assist device, and number of days with renal replacement therapy among others (other secondary endpoints included in text). Total of 336 patients were randomized ...
Jean-Paul Mira shares his thoughts on the LICORN trial which sought to answer the question: Does a prophylactic levosimendan infusion reduce the incidence of postoperative low cardiac output syndrome in patients with impaired left ventricular function who are undergoing isolated or combined coronary artery bypass grafting surgery under cardiopulmonary bypass?. Results from this trial were presented at LIVES 2017 in Vienna and have been published in JAMA.. Find the article in JAMA HERE.. ...
This report provides top line data relating to the clinical trials on Low Cardiac Output Syndrome. Report includes an overview of trial numbers and their average enrollment in top countries conducted across the globe...
The Report Low Cardiac Output Syndrome Global Clinical Trials Review, H2, 2016 provides information on pricing, market analysis, shares, forecast, and...
Neonates and infants that have cardiac surgery with cardiopulmonary bypass (CPB) for congenital heart disease are at great risk for experiencing life-threatening low cardiac output syndrome (LCOS) in the first 24 hours after surgery. The poor perfusion and inadequate oxygen delivery that occurs may result in multiple organ failure and death. It is LCOS that is responsible for the majority of early postoperative deaths in this population of neonates and infants. Improved pediatric probes placed in peripheral locations using near infrared spectroscopy (NIRS) may permit continuous monitoring of venous saturations reflecting overall perfusion and oxygen balance in the tissues. Following parental or guardian consent, 30 neonates and infants scheduled to undergo surgery for congenital heart disease will be enrolled. At the end of surgery, four EQUANOX Advance 8004CB probes will be placed on the flank, lower extremities and the forehead. Continuous NIRS saturations will be monitored and stored for ...
Acute heart failure represents an increasingly common cause of hospitalization, and may require the use of inotropic drugs in patients with low cardiac output and evidence of organ hypoperfusion. However, currently available therapies may have delete
Low cardiac output syndrome (LCOs) is a serious complication in critically ill patients or those undergoing major surgery, resulting in multiple organ damage with significant in-hospital and long-term morbidity and mortality, as well as prolonged hospital stay. In this setting the mortality rate is distressingly high despite improvements in intensive care treatment, but survivors have an acceptable quality of life ...
Mean age at operation were 67.8 ± 9.6 years (group 1) and 63.9 years ± 9.5 (group 2), respectively. There were no significant differences in preoperative risk factors, including smoking, hypertension, diabetes mellitus, dyslipidemia, obesity, stroke, left ventricular dysfunction, and chronic renal failure between the 2 groups. Mean number of distal anastomosis was 2.93 ± 1.0 in group 1 and 3.09 ± 0.97 in group 2 (p=0.133). Operative mortality was 1.1% (1/91) in group 1 and 1.3% (26/1991) in group 2, respectively (p=1.000). There were no significant differences in postoperative morbidities, including mediastinitis, re-exploration for bleeding, perioperative myocardial infarction, low cardiac output syndrome, atrial fibrillation, and stroke between the 2 groups. ...
The 8S58021I is a high speed 1-to-4 Differential-to-LVPECL/ECL Fanout Buffer. The 8S58021I is optimized for high speed and very low output skew, making it suitable for use in demanding applications such as SONET, 1 Gigabit and 10 Gigabit Ethernet, and Fibre Channel. The internally terminated differential input and VREF_AC pin allow other differential signal families such as LVDS, LVPECL and CML to be easily interfaced to the input with minimal use of external components. The 8S58021I is packaged in a small 3mm x 3mm 16-pin VFQFN package which makes it ideal for use in space-constrained applications.. ...
The new drop-ins that you have scheduled for December look very promising. Q5 WG binned Crees for the M60 Output will be 220+ lumens for approx 2 hrs Low output version of 130 lumens for 6 hrs on 2 primary CR123s Best of Luck Gene in your NEW full time job. You make a great product!
TY - JOUR. T1 - Effect of Adjustable Passive Constraint on the Failing Left Ventricle. T2 - A Finite-Element Model Study. AU - Jhun, Choon-Sik. AU - Wenk, Jonathan F.. AU - Zhang, Zhihong. AU - Wall, Samuel T.. AU - Sun, Kay. AU - Sabbah, Hani N.. AU - Ratcliffe, Mark B.. AU - Guccione, Julius M.. PY - 2010/1/1. Y1 - 2010/1/1. N2 - Background: Passive constraint is used to prevent left ventricular dilation and subsequent remodeling. However, there has been concern about the effect of passive constraint on diastolic left ventricular chamber stiffness and pump function. This study determined the relationship between constraint, diastolic wall stress, chamber stiffness, and pump function. We tested the hypothesis that passive constraint at 3 mm Hg reduces wall stress with minimal change in pump function. Methods: A three-dimensional finite-element model of the globally dilated left ventricle based on left ventricular dimensions obtained in dogs that had undergone serial intracoronary microsphere ...
Neonates and infants that have cardiac surgery with cardiopulmonary bypass (CPB) for congenital heart disease are at great risk for experiencing life-threatening low cardiac output syndrome (LCOS) in the first 24 hours after surgery. The poor perfusion and inadequate oxygen delivery that occurs may result in multiple organ failure and death. It is LCOS that is responsible for the majority of early postoperative deaths in this population of neonates and infants. Improved pediatric probes placed in peripheral locations using near infrared spectroscopy (NIRS) may permit continuous monitoring of venous saturations reflecting overall perfusion and oxygen balance in the tissues. Following parental or guardian consent, 30 neonates and infants scheduled to undergo surgery for congenital heart disease will be enrolled. At the end of surgery, four EQUANOX Advance 8004CB probes will be placed on the flank, lower extremities and the forehead. Continuous NIRS saturations will be monitored and stored for ...
Congenital heart disease (CHD) is a major cause of infant mortality. Many infants with CHD require corrective surgery with most operations requiring cardiopulmonary bypass (CPB). CPB triggers a systemic inflammatory response which is associated with low cardiac output syndrome (LCOS), postoperative morbidity and mortality. Delivery of nitric oxide (NO) into CPB circuits can provide myocardial protection and reduce bypass-induced inflammation, leading to less LCOS and improved recovery. ...
icTV) Commentary on the LICORN Randomised Clinical Trial Jean-Paul Mira shares his thoughts on the LICORN trial which sought to answer the question: Does a prophylactic levosimendan infusion reduce the incidence of postoperative low cardiac output syndrome in patients with impaired left ventricular function who are undergoing isolated or combined coronary artery bypass grafting surgery under […]. Read More…. ...
For this pump to work well it needs a good supply of fuel and oxygen and this is achieved through good blood supply. However, there is a second aspect which is largely ignored by cardiologists and other doctors. The heart needs to be able to convert this fuel and oxygen supply into a usable form of energy for the muscle cells to work. This is achieved by mitochondria. They take fuel and oxygen from the blood and through a complex series of biochemical reactions, including Krebs citric acid cycle and oxidative phosphorylation, they generate ATP, the currency of energy in the body. Each heart cell will hold between 2,000 - 3,000 mitochondria. The reason it needs so many is that the heart never gets a rest - it has to work 24/7! An interesting observation here is that the heart is rich in oxygen and mitochondria - when the latter gets switched off, this is a major risk factor for cancer. One never sees cases of primary cancer of the heart! The heart is only responsible for 60% of blood pressure - ...
Patients in arm 1 will have their blood pressure raised in order to improve cerebral blood flow (CBF). In case of a low cardiac output, inotropics will be added. Induced hypertension will be continued for at least 48 hours when patients show some improvement within the first 24 hours. After 48 hours, the dose of vasopressor will be tapered daily, and resumed in case of clinical deterioration. In patients who do not show any improvement within 24 hours, induced hypertension will not be continued. In patients in arm 2 of the trial, hypertension will not be induced. Patients in both arms of the trial will be treated with oral nimodipine and normovolaemia without haemodilution. In some selected centres, an extra perfusion CT scan is performed 24-36 hours after instalment of the treatment. Measurement of CBF is performed in all participants with perfusion CT-scanning of the brain at the beginning of the study (as part of regular patient care), and after 24-36 hours ...
Former Vice President Dick Cheney suffered a mild heart attack, but was feeling good and was expected to leave the hospital this week, his office said in a statement on Tuesday.
​The actors wife told CNN he never fully recovered from a horrible car accident two and a half years ago in which he was injured very badly.​
Veteran actor Sumita Sanyal, who essayed supporting characters in Anand and Satyajit Rays Nayak, died today at her south Kolkata residence.
Malocclusion is the technical name for a bad bite and refers to problems with talking, chewing, biting and swallowing food. It can also affect your facial appearance. Your bite is the name given to the action of opening and closing your jaws. Your jaws are connected via a small joint which acts in a similar manner to a hinge and enables them to work in a smooth, co-ordinated manner. But problems can occur with your jaw, such as temporomandibular joint disorder (TMJ) which can be both painful and distressing. Treatment for this can include the fitting of a corrective brace. Problems with your bite can also include an underbite or an overbite: an underbite occurs when your lower jaw and teeth protrude forward which means that they close in front of your upper teeth. An overbite is where the opposite happens: when you close your jaws you notice that your upper teeth protrude in front of your lower teeth. What causes malocclusion? There are a variety of factors which cause this which ...
Four patients in c-CABG group died of low cardiac output syndrome and CVA. There was no operative mortalities in OPCAB group (p = .023). Bleeding requiring reopening (5:1, p = .05) and CVA (3:0, p = .05) occurred more frequently in c-CABG group than OPCAB group. The completeness of follow-up was 83.8%.. Late deaths occurred in 26 patients (11 [18.0%] in c-CABG group, 15 [16.9%] in OPCAB group). The causes of death were cancer, CVA, cardiac and sepsis.. Rerevascularization was performed more frequently in OPCAB group than in c-CABG group (14:5, p = .297). Five-year overall survival, freedom from cardiac death and MACE in c-CABG and OPCAB groups were 90.2 vs 96.6 %, 98.4 vs 100 %, and 91.8 vs 85.4 %, respectively. Ten-year survival estimates were 82.0 vs 83.1 %, 96.7 vs 96.6 %, and 88.5 vs 83.1 %, respectively. There were no statistical significance between 2 groups survival (p = .743 in overall survival, P = .813 in free from cardiac death, and p = .305 in free from MACE). Age was an independent ...
The present clinical series from a single institution illustrates the evolution of management strategies over the past two decades for the challenging condition of PAIVS. In patients with a diminutive RV and RV dependent coronary circulation, the management is palliative systemic-pulmonary arterial shunt insertion and subsequent univentricular repair. In those with anatomically suitable RVs, laser assisted valvotomy with balloon valvoplasty has become the procedure of choice in our institution. However, regardless of the initial procedure, multiple interventions are often required in the subsequent treatment algorithm, especially for patients after CPV and laser assisted pulmonary valvotomy with balloon dilatation. Nonetheless, the risk of developing low cardiac output syndrome is significantly less after catheter intervention than after either RVOTR or CPV. Although survival of patients after RVOTR appeared worse than survival after CPV or primary catheter intervention, the difference was not ...
Measurements and results: Subjects were observed for 24 hours; during surgery, 6 and 24 hours after aortic clamp removed. During July 2012 - December 2013, there were 52 patients who became subjects. There were proportion differences between cardiac lactate and cardiac output change after cardiac surgery. Increase of cardiac lactate has a correlation with increasing levels of sTNFR-1 and IL-6 and decreasing index of Tc, ScvO2 and cardiac output. There were correlations among low index of ScvO2, high index of cardiac lactate and decrease of cardiac output. High sTNFR-1 and IL-6 were correlated to low cardiac output. Cardiac lactate, ScvO2 and MAP can be used as predictors of cardiac output change in patients with cardio-pulmonary bypass. sTNFR-1 and IL-6 levels were correlated with cardiac output changes after cardiac surgery ...
The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecules storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters. ...
Studies are showing that loneliness is a risk factor for a number of health issues. Problems like disturbed sleep and low cardiac output, which can lead to an imbalance between oxygen delivery and oxygen consumption leading to metabolic acidosis (when the body produces excessive quantities of acid), are being linked to prolonged feelings of loneliness.. The studies have found that social isolation makes people vulnerable to disease and can shorten life. When looking at the findings of many similar studies, the results suggest that loneliness is as risky to health as obesity.. An interesting fact has emerged from the studies too that show that some people may have a hereditary disposition for feelings of loneliness. In twin studies it was found that though loneliness may change across a lifespan according to environmental factors, there did appear to be evidence of genetic contribution.. It is worth noting too that these studies were conducted across various age ranges, from young adults to the ...
Mild heart attack symptoms can be treated through proper medication, which has been recommended or prescribed by your physician. Prevention is critical.
According to the article, he passed away at Cedars-Sinai Hospital after a five-year battle with heart disease, with his father Dave Hallett by his side.A private funeral service is planned at his home in Cape Cod.. ...
TY - JOUR. T1 - New strategy for chronic heart failure. AU - Togane, Yuko. AU - Fukuda, Keiichi. PY - 2004/6/1. Y1 - 2004/6/1. UR - http://www.scopus.com/inward/record.url?scp=3042712173&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=3042712173&partnerID=8YFLogxK. M3 - Review article. AN - SCOPUS:3042712173. VL - 52. SP - 633. EP - 637. JO - Respiration and Circulation. JF - Respiration and Circulation. SN - 0452-3458. IS - 6. ER - ...
What better way to say goodbye to the year 2010 than to count down the 10 biggest stories of the year in professional wrestling? This 10-part series is designed to do exactly ...
This is Digital Version of (Ebook) 978-1461469186 Surgical Treatment for Advanced Heart Failure Product Will Be Delivered Via Email Or Cloud Drive Wit
With minimalistic circuit design best sound quality is achieved without any compromise. Only one transistor is responsible for amplification of the low MC signals. Overallfeedback, differential amplification and push-pull circuits are not used. Adjustment of the MC imput impedance to the pick-up is superfluous due to the use of a current control circuit. Tubes are only installed where they are able to develop their whole range of advantages: for prevention of natural harmonic spectrum, fusion of neutrality and liveliness as well as the exceptional dynamics. One output transistor guarantees low output impedance to drive long cables without losses ...
Rotea performance and applications data highlight high T-cell and PBMC recovery and viability, with high cell concentrations in low output volumes.
Fruit Plus Menthol Mr Salt-E E-Juice 30mL is a unique yet satisfying blend of fruit and menthol that is crafted using a salt-based nicotine for use in low output pod
The Dimplex 400W low wattage panel heater is an ideal background heating solution for rooms where there is the need to keep a chill off, such as hallways or small bedrooms. Slimline and simple to use, this low output freestanding panel heater has a 24 hour timer with single heat setting operated by a side switch and comes complete with fitted plug. Comes with a 3 year guarantee.. This product is only suitable for well insulated spaces or occasional use. ...
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(PRWEB) June 9, 2005 -- The first 10 Heart Failure patients all over the world who received Embryonic-Fetal Human Stem Cells directly into their hearts were
Learn more about Diagnosis of Heart Failure at Grand Strand Medical Center Main Page Risk Factors Symptoms ...
Learn more about Screening for Heart Failure at Grand Strand Medical Center Main Page Risk Factors ...
Study Flashcards On Medical 6-MS38-Heart failure at Cram.com. Quickly memorize the terms, phrases and much more. Cram.com makes it easy to get the grade you want!
A 17-year-old girl suffered from heart failure due to an infection that she may have picked up when she had her ears pierced a year earlier.
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This weeks View focuses on several recent papers having to do with cardiac surgery, specifically a 5-year trial comparing off-pump and on-pump coronary artery bypass graft surgery (CABG), outcomes of transcatheter mitral valve replacement in patients with failed mitral bioprosthetic valves and annuloplasty rings, and a study on the use of levosimendan in patients undergoing CABG to prevent low cardiac output syndromes.
Hospitalizations for acute heart failure are associated with high mortality and readmission rates. Ten to 20% of the patients have signs of low cardiac output and fluid overload. The administration of inotropic agents to correct these hemodynamic abnormalities may be indicated in these patients. However, the risk to benefit ratio of inotropic agents is high and an increase of untoward effects and mortality has been suggested by many retrospective analyses and meta-analyses. Limitations of inotropic therapy seem mainly related to their mechanisms of action based, in the case of the traditional agents, on an increase in intracellular cyclic AMP and calcium concentrations. Concomitant peripheral vasodilation, such as in the case of the novel agent levosimendan is another important limitation, above when patients are hypotensive and/or treated with vasodilators and high doses of diuretics. Myosin activators, histaroxime, sarcoplasmic reticulum ATPase activators and metabolic agents seem promising as active
I had pigs with heart issues before, which were caught too late, due to the fact that vets in Belgium are usually not well educated about piggies at all. Despite that I had my suspicions about each and every pig, had the pigs heart examined, the vets didnt bother and the pigs died from the consequences, meaning one pig developed pneumonia, one from dental issues, one suddenly developed bladder grit at an older age and didnt recover after anesthesia for rinsing her bladder, one had an averse reaction to pain meds and caused heart failure. Plus, until 2011, no heart meds were prescribed for pigs in Belgium ...
FRIDAY, Aug. 28, 2020 (HealthDay News) -- Flu and pneumonia vaccines lead to fewer hospital deaths among heart failure patients, a new study finds.. Our study provides further impetus for annual immunizations in patients with heart failure. Despite advice to do so, uptake remains low, said study author Dr. Karthik Gonuguntla, of the University of Connecticut.. In heart failure, your heart cant pump blood as well as it should. This leads to fluid buildup in the lungs that causes shortness of breath, coughing and reduced quality of life. Respiratory infections like pneumonia and the flu make heart failure worse, so annual vaccinations are recommended for patients. However, few studies have compared outcomes among heart failure patients who have and havent received these vaccinations.. In this study, the researchers looked at nearly 3 million heart failure patients, average age 70, in the United States who were hospitalized between 2010 and 2014. Only 1.4% of the patients had received the flu ...
Next to a dime for perspective, this small wire device is designed to hold open a surgically created hole in the heart of diastolic heart failure patients.
Get all the latest news and updates on Heart Failure only on News18.com. Read all news including political news, current affairs and news headlines online on Heart Failure today.
Acute Kidney Injury, Adult, Association, Bleeding, Blood, Cardiac Output, Cardiac Surgery, Confidence Interval, Hematocrit, Hemodilution, Hospital, Injury, Kidney, Low Cardiac Output, Mechanical Ventilation, Methods, Morbidity, Mortality, Odds Ratio, Patient
Heart failure or congestive heart failure (CHF) is known as the structural or functional disorder of the heart that impairs its ability to pump a sufficient amount of blood throughout the body. Due to inefficient pumping ability, fluid starts to buildup in the legs, ankles and feet (edema). Coronary artery disease, high blood pressure and diabetes are the primary causes that lead to congestive heart failure. About 5 million people in the United States alone suffer from this condition and each year approximately 300000 people die due to heart failure.. Heart failure increases the pressure in the heart because blood moves through the heart and the body at a slower rate. Thus the heart loses its ability to pump oxygenated blood and nutrients to other parts of the body. During heart failure, the heart does not cease completely but loses the efficiency to pump blood all around the body. Heart failure leads to reduction in muscle contraction and the ability of the heart chambers to fill up with blood ...
Most of you probably understood the first scenario easily. This patient has a low cardiac output despite a normal blood pressure. This is a completely normal finding in cardiogenic shock, which is a pump failure-a lack of forward flow-rather than a hypotensive state.. Arterial blood pressure is primarily maintained by vasomotor tone, which is why most of the shock we see is distributive (i.e. vasodilatory) in nature. In Guytonian physiology, the vascular pressure in the absence of any flow-the mean systemic filling pressure-is not zero, but it is very low (,20 mmHg). Low flow can eventually be a primary cause of arterial hypotension, but only in end stages; most cardiogenic shock is normotensive, or even hypertensive. As always, the wild card is vascular resistance, which can vary in either a compensatory or decompensated manner.. To make a long story short, flow and pressure are largely independent in cardiogenic shock, which means that we can no longer use blood pressure as a surrogate for ...
This week, we are dedicating our post to heart failure, in honor heart failure awareness week. Heart failure is a condition affecting over 5 million people in the US. Despite its name, heart failure doesnt mean your heart has stopped beating. Heart failure is a condition where the heart isnt pumping enough blood to sustain your bodys oxygen and blood needs. Consuming too much sodium may cause your heart to work harder and worsen a heart failure condition. Whether you have heart failure and are trying to manage it or are just trying to follow a healthy lifestyle, here are some tips for following a low sodium diet, tried and tested by the experts on our team. ...
Israeli companies are developing monitoring devices aimed at improving quality of life and avoiding hospital readmissions for CHF patients.
We are really sorry that you had such a traumatic event occur during your treatment for angina in the emergency room. Our article is about heart failure, specifically at the end of life. We conclude that At the end of life, morphine is the most important medicine for providing comfort to heart patients. It reduces the breathless feeling that can be so frightening to people at the end of life. Pathways stands by this information which is a standard in hospice care for dying patients.. ReplyDelete ...
This quality standard covers assessing, diagnosing and managing chronic heart failure in adults (aged 18 and over). It describes high-quality care in priority
TY - JOUR. T1 - Cognitive Functioning and Chronic Heart Failure:A Review of the Literature (2002-July 2007). AU - Pressler, Susan J.. PY - 2008/1/1. Y1 - 2008/1/1. N2 - The purposes of this article are to (1) summarize the state of the science about cognitive impairment and heart failure (HF) using the results of a literature search of publications from 2002 through July 2007; (2) provide a focused review of the studies that used a prospective, longitudinal design with measurement at 2 or more time points in order to identify change in cognitive functioning; and (3) identify gaps and priorities for future studies. A computer search of the literature from 2002 through July 2007 was conducted. All of the resulting 97 references were reviewed, categorized into 8 groups, and evaluated. The 97 studies were categorized as follows: those not directly related to cognitive impairment (n = 15); comments, letters to the editor, and brief summaries (n = 11); reviews (n = 15); data-based publications using ...
Heart failure (HF), also referred to as congestive heart failure, occurs when heart loses the ability to provide sufficient pump action to maintain blood flow. Most of the signs of a heart failure occur as a result of the congestion that develops
A study in nearly 15 000 heart failure patients has found that up to 80% may not be receiving treatment at doses proven to reduce hospitalisations and improve survival. The research presented at ESC Congress 2016 today highlights the need for doctors to ensure patients are treated appropriately so that the high levels of serious illnesses and death associated with heart failure can be reduced.
Question - What is the life expectancy of stage three heart failure patients ?. Ask a Doctor about diagnosis, treatment and medication for Heart failure, Ask a Cardiologist
As I see it, the best use for a JFET buffer is on the input of a pedal, not the output. It can give you an input impedance of more than 1M Ohm, which is great, and it can give you some nice soft clipping. Putting it on the output is less useful, because youre not going to get the really low output impedance youd like, and youre probably not going to get the benefit of the nice clipping sound, so easily. Using it with a fairly high value output pot is just pointless - youre back to high output impedance, when you turn the volume down, so you start to lose bass again ...
RT8062 2A, 2MHz, Synchronous Step-Down Converter General Description Features The RT8062 is a high efficiency synchronous, step-down DC/DC converter. Its input voltage range is from 2.7V to 5.5V and provides an adjustable regulated output voltage from 0.8V to 5V while delivering up to 2A of output current. z High Efficiency : Up to 95% z Adjustable Frequency : 200kHz to 2MHz No Schottky Diode Required 0.8V Reference Allows Low Output Voltage Low Dropout Operation : 100% Duty Cycle Enable Function Internal Soft-Start RoHS Compliant and Halogen Free The internal synchronous low on resistance power switches increase efficiency and eliminate the need for an external Schottky diode. The default switching frequency is set at 2MHz, if the RT pin is left open. It can also be varied from 200kHz to 2MHz by adding an external resistor. Current mode operation with external compensation allows the transient response to be optimized over a wide range of loads and output capacitors. z z z z z z Applications z ...
This paper has two parts. In the first part, I demonstrate that, in the absence of price and wage bounds, monetary models do not have current equilibria - and so lack predictive content - for a wide range of possible policy rules and/or beliefs about future equilibrium outcomes. This non-existence problem disappears in models in which firms face (arbitrarily loose) finite upper bounds on prices or positive lower bonds on nominal wages. In the second part, I study the properties of a class of dynamic monetary models with these kinds of bounds on prices/wages. Among other results, I show that these models imply that the Phillips curve is L-shaped, are consistent with the existence of permanently inefficiently low output (secular stagnation), and do not imply that forward guidance is surprisingly effective. I show too that economies with lower nominal wage floors have even worse equilibrium outcomes in welfare terms. It follows that models with arbitrarily low but positive nominal wage floors are ...
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Heart failure is a condition that is caused by the heart failing to pump enough blood around the body at the right pressure. Common symptoms of heart failure include breathlessness, fatigue and ankle swelling. The risk of developing heart failure can be reduced by maintaining a healthy lifestyle such as taking regular exercise, eating well and by not smoking.. The figure shows that the QOF prevalence of heart failure for most GP surgeries in NHS Horsham and Mid Sussex CCG is smaller than the modelled prevalence.. ...
Up to 80% of heart failure patients may not be receiving treatment at doses proven to reduce hospitalizations and improve survival.
Transitional Care of Heart Failure Patients: free Medicine sample to help you write excellent academic papers for high school, college, and university. Check out our professional examples to inspire at EssaysProfessors.com
The Heart Failure Association (HFA) of the European Society of Cardiology (ESC) is calling for global policy change relating to heart failure. An international white paper, Heart failure: preventing disease and death worldwide, ...
Heart failure is a clinical syndrome, learn about Heart Failure Diagnosis and Investigation on our Heart Failure Diagnosis and Investigation page
Learn more about Symptoms of Heart Failure at Doctors Hospital of Augusta Main Page Risk Factors Symptoms ...
Learn more about Diagnosis of Heart Failure at Doctors Hospital of Augusta Main Page Risk Factors Symptoms ...
Learn more about Treatments for Heart Failure at Portsmouth Regional Hospital Main Page Risk Factors ...
Learn more about Screening for Heart Failure at Portsmouth Regional Hospital Main Page Risk Factors ...
At MaineHealth, patients with heart failure, including congestive heart failure, get comprehensive diagnosis and treatment of their heart conditions.
Heart failure means the heart has a reduced ability to pump blood around the body. Congestive heart failure refers to the symptoms that occur in heart failure from excess fluid accumulation.
Although the term heart failure sounds frightening, this condition is usually treatable. Heart failure does not mean that the heart has stopped working.
Although the term heart failure sounds frightening, this condition is usually treatable. Heart failure does not mean that the heart has stopped working.
Although the term heart failure sounds frightening, this condition is usually treatable. Heart failure does not mean that the heart has stopped working.
FDA approved the fixed-dose combination heart failure drug sacubitril/valsartan to reduce risk of CV death and hospitalization in patients with chronic heart failure.
Several scores based on symptoms and signs have been developed to assess the presence of heart failure. The goal of this study was to compare six heart failure scores in non-hospitalised subjects and to determine their usefulness in population based research. The scores were applied to 54 participants of a population based study. All underwent...
Treatment for the symptoms of heart failure varies depending on the stage of heart failure. Stage A heart failure is generally treated using lifestyle modifications and medications, while Stage B...
Along with the above, the most surprised patients are those who survive a heart attack and go home on five new medicines. These many medicines do not mean that you are very ill, but rather that physicians know from experimental studies that each of these five medicines will reduce your chance of a second heart attack (and remember that the single greatest risk for having a heart attack is already having had one). The medicines are: a platelet blocker (aspirin, Plavix, or Coumadin), a beta-blocker, a statin to lower your cholesterol and stabilize any atheromatous plaques in your coronary arteries, an ACE inhibitor or an ARB, and, if you are in any heart failure at all, spironalactone. Again, these are all to reduce your chance of having a second heart attack, and should be taken exactly as prescribed. ...
Heart failure occurs when the heart cant pump enough blood to meet the bodys needs. It can follow a heart attack or develop gradually over many years. Learn more about heart failure from our experts.
Sometimes a story hits your right in the heart. Matt Foggs experience with battling chronic heart failure to eventually overcoming it is one of those.
Heart failure is a condition in which the heart doesn’t pump blood as it should. Find out more on heart failure causes, symptoms, and treatment.
Read more about Exercising for 30 minutes lowers risk of heart failures on Business Standard. Heart failure is a chronic, progressive condition in which the heart muscle is unable to pump enough blood through to meet the bodys needs for blood and oxygen.Though there is no cure for this condition, one can choose to lead a healthy lifestyle
How to Recognize Symptoms of Heart Failure Exacerbation. Heart failure is a condition in which the pumping mechanism of the heart is weakened, and it is unable to circulate blood at a normal pace. As a result, fluid backs up into different...
Your doctor will likely prescribe medications for heart failure and any underlying health problems you have. Most people with heart failure take one or more types of medication. Your healthcare provider will work to find the combination of medications that works best for you.
To evaluate your condition, your doctor will examine you, ask questions, and run tests. Along with looking for signs of heart failure, the doctor looks for any other health problems that may have led to heart failure.
Richards, D. G.; Whitfield, A. G.; Arnott, W. M.; Waterhouse, J. A. (1951). "The Lung Volume in Low Output Cardiac Syndromes". ...
Cardiac output increases through an increase in heart rate. The body's response to high altitude includes the following: ↑ ... Those individuals with the lowest initial partial pressure of end-tidal pCO2 (the lowest concentration of carbon dioxide at the ... with constant or increased cardiac output, also leads to increases in capillary pressures. For those suffering HACE, ... Descent to lower altitudes alleviates the symptoms of HAPE. HACE is a life-threatening condition that can lead to coma or death ...
"Caveolae protect endothelial cells from membrane rupture during increased cardiac output". The Journal of Cell Biology. 211 (1 ... Lim, Ye-Wheen; Lo, Harriet P.; Ferguson, Charles; Martel, Nick; Giacomotto, Jean; Gomez, Guillermo A.; Yap, Alpha S.; Hall, ... Lo, Harriet P; Hall, Thomas E; Parton, Robert G (2016-01-13). "Mechanoprotection by skeletal muscle caveolae". Bioarchitecture ... Bastiani, Michele; Liu, Libin; Hill, Michelle M.; Jedrychowski, Mark P.; Nixon, Susan J.; Lo, Harriet P.; Abankwa, Daniel; ...
Plasma expansion may be necessary if hypotension and low cardiac output develop.[citation needed] Hypertonic saline may be ...
This initially reduces blood volume, decreasing blood return to the heart and thus cardiac output. It is believed to lower ... low magnesium), hyponatremia (low sodium), and hypercalcemia (high calcium) Hyperuricemia (high levels of uric acid in the ... Additionally, by other mechanisms, HCTZ is believed to lower peripheral vascular resistance. In a double-blind, randomized ... Potential side effects include poor kidney function; electrolyte imbalances, including low blood potassium, and, less commonly ...
It may be due to low cardiac output (as seen in shock, congestive cardiac failure), hypovolemia, valvular heart disease (such ... Conditions associated with low cardiac output and high systemic vascular resistance can produce a dicrotic pulse. Pulsus ... increased cardiac output, increased stroke volume (as seen in anxiety, exercise, complete heart block, aortic regurgitation), ... A low tension pulse (pulsus mollis), the vessel is soft or impalpable between beats. In high tension pulse (pulsus durus), ...
Blocking β adrenergic receptors decreases the heart rate and cardiac output to lower arterial blood pressure. β blockers also ... Penbutolol has a low frequency of side effects. These side effects include dizziness, light headedness, and nausea. Penbutolol ... It may mask signs of low blood sugar in people with diabetes and it may mask signs of hyperthyroidism. Animal studies showed ... decrease renin levels, which ultimately results in less water being reabsorbed by the kidneys and therefore a lower blood ...
... and cardiac output are measured by stretch receptors found in the carotid arteries. Nerves embed themselves within these ... Hypovolemia, or low fluid levels in the body, can also act as a stimulus to cause this response. Epinephrine, also known as ... Hypotension, or low blood pressure, is a large driving force for the release of vasopressin, a hormone which causes the ... These impulses inhibit the constriction of blood vessels and lower the heart rate. If these nerves do not detect stretching, ...
... of the total cardiac output. If blood flow to the colon drops by more than about 50%, ischemia will develop. The arteries ... Causes of the reduced blood flow can include changes in the systemic circulation (e.g. low blood pressure) or local factors ... If possible, cardiac function and oxygenation should be optimized to improve oxygen delivery to the ischemic bowel. A ... As a result, during periods of low blood pressure, the arteries feeding the colon clamp down vigorously; a similar process can ...
... is a postperfusion syndrome characterized by low systemic vascular resistance and a high cardiac output. VPS occurs more ... Vasoplegic syndrome is defined as low systemic vascular resistance (SVR index 2.5 l/min/m2) within the first 4 postoperative ... "BestBets: Is Methylene Blue of benefit in treating adult patients who develop vasoplegic syndrome during Cardiac Surgery". ...
... increases cardiac output and improves gas exchange while lowering PAP and PVR. A subset of patients does not respond to any ... Epoprostenol therapy can lower PAP by 29-46% and PVR by 21-71%., Ilioprost shows no evidence of generating tolerance, ... High cardiac index and pulmonary capillary wedge pressures, however, may lead to false positives by this standard. By one ... Patients tend to have a poor cardiac status, with 60% having stage III-IV NYHA heart failure. PPH is actually independent of ...
Initially, diuretics lower blood pressure by decreasing cardiac output and reducing plasma and extracellular fluid volume. ... Eventually, cardiac output returns to normal, and plasma and extracellular fluid volume return to slightly less than normal, ... Other side effects may include gout, low blood magnesium, high blood calcium, allergic reactions, and low blood pressure. Some ... Common side effects include low blood potassium, low blood sodium, high blood sugar, dizziness, and erectile dysfunction. ...
In some cases, it may be contraindicated in people with low platelets, increased intracranial pressure, or decreased cardiac ... output. Due to the risk of disease progression, it is also potentially contraindicated in people with preexisting progressive ... Some surgeries that spinal analgesia may be used in include lower abdominal surgery, lower limb surgery, and perineal surgery. ... Epidurals other than low-dose ambulatory epidurals also impact the ability of the mother to move during labor. Movement such as ...
This behavior facilitates a much greater increase in stroke volume and cardiac output at a lower mean arterial pressure and ... insufficient preload leading to reduced cardiac output). If the pulse pressure is extremely low, i.e. 25 mmHg or less, the ... ISBN 978-1-880696-31-6. DETERMINATION OF CARDIAC OUTPUT IN MEDICAL STUDENTS BY PULSE PRESSURE METHOD, Farida Munawar, Fareeha, ... The most common cause of a low (narrow) pulse pressure is a drop in left ventricular stroke volume. In trauma, a low or narrow ...
Pregnancy leads to high venous pressure in the lower limbs, decreased blood return to the heart, decreased cardiac output due ... This is caused by the decreased preload, decreased cardiac output, and leads to increased frequency. In pregnant women, signs ... Edema of the lower extremities (peripheral edema), caused by an increase in the venous blood pressure. Tachycardia. ...
Cardiac output (mL/minute) can be calculated by multiplying heart rate (beats/minute) by stroke volume (mL/beat). Like other ... Instead it is sent via the ureters to the cloaca to be deposited into the lower intestine. The epithelium of the lower ... In response, the common raven experiences an increased heart rate and cardiac output. Another method used by many species of ... In general, birds have larger heart sizes and higher cardiac output. During flight, birds can sustain their heart rates, and ...
Cardiac output (CO) is defined as the amount of blood pumped by the ventricle in unit time. In mathematical terms, CO = SV × ... Low EF usually indicates systolic dysfunction, and severe heart failure can result in EF lower than 0.2. EF is also used as a ... Cardiomyopathy and heart failure cause a reduction in cardiac output, whereas infection and sepsis are known to increase ... This makes it an improved index of systolic function over other hemodynamic parameters like ejection fraction, cardiac output, ...
Eccentric contractions and cardiac output: With lower cost of oxygen how would eccentric exercise affect the heart? A study was ... Due to the high strain on muscles during eccentric training, coupled with low energy output, eccentric training becomes a ... The rehabilitative nature, low energy costs, high magnitudes of force, and low uptake of oxygen all align eccentric exercise ... and low oxygen demand make low-intensity eccentric exercise ideal for the elderly. Eccentric contraction and oxygen consumption ...
These two changes help to regulate the cardiac output, so that a sufficient amount of blood reaches tissues. This function is ... the vagus nerve, part of the parasympathetic branch of the autonomic nervous system, to lower heart rate. The cardiovascular ... The cardiovascular centre affects changes to the heart rate by sending a nerve impulse to the cardiac pacemaker via two sets of ... resulting in faster and stronger cardiac muscle contraction. This increases heart rate. Many anaesthetics depress the activity ...
Patients who have labile hypertension may have higher cardiac output and lower total peripheral resistance than others. ... The effect of taking beta blockers can help lower the heart rate as well as help improve the blood flow by opening up the blood ... By reducing alcohol intake, the systolic blood pressure will lower by 2-4mm Hg and the diastolic blood pressure by 1-2 mm Hg.[ ... Electrodes are placed on the surface of the skin and connected to the amplifier to detect electrical changes in the cardiac ...
Boron, Walter F.; Boulpaep, Emile L. (2011). "Chapter 23: Regulation of Arterial Pressure and Cardiac Output". Medical ... This results in an increase in the pressure of the right atrium, which stimulates the atrial stretch receptors (low pressure ... now restores venous return and cardiac output into a vasoconstricted circulation, stimulating the vagus nerve and leading to a ... "Effects on cardiac contractility and stroke volume are insignificant." Bainbridge reflex can be blocked by atropine and can be ...
Junctional rhythms (if a bradycardia) can cause decreased cardiac output. Therefore, the person may exhibit signs and symptoms ... similar to other bradycardia such as lightheadedness, dizziness, low blood pressure, and fainting. This rhythm can usually be ... Ectopic beat Junctional rhythm Abedin, Zainul; Conner, Robert (2012). Interpretation of Cardiac Arrhythmias: Self-Assessment ...
... can cause a number of cardiac issues, such as arrhythmia, low cardiac output syndrome, and myocardial ... although the surgery itself can cause reduced cardiac output in the short term. After surgery, many patients will have a chest ... The most common complication after surgery is reduced cardiac output, which occurs in between 14% and 28% of patients. ... Uncommon Cardiac Diseases", Kaplan's Essentials of Cardiac Anesthesia (Second Edition), Philadelphia: Elsevier, pp. 426-472, ...
"Total replacement artificial heart and driving system with inherent regulation of cardiac output". Transactions of the American ... "A prosthetic heart with hemispherical ventricles designed for low hemolytic action". Transactions of the American Society for ...
They also reduce the heart rate and contractility to lower the cardiac output, which in turn lower blood pressure. Amlodipine, ... When the rate of blood flow is too low, there may be a blockage of vessel. By evaluating blood flow in vessels, the severity ... Statins and fibrates can also be prescribed to lower blood cholesterol level and hence reducing the risk of plaque formation in ... It is more common to be found in lower limbs than upper limbs. Erythromelalgia initiated from dysfunction of peripheral nerves ...
... it does not increase contractility force and output of the cardiac muscle. It may increase blood pressure resulting in a slow ... The low concentration eye drops do not cause blood pressure changes and the changes with the higher dose drops do not last long ... Patients taking these medications may need a lower dose of phenylephrine to achieve a similar increase in blood pressure. Drugs ... Phenylephrine may cause side effects such as headache, reflex bradycardia, excitability, restlessness and cardiac arrhythmias. ...
For heart patients with low cardiac output and who are not candidates for cardiac transplantation, a procedure called ...
Since blood pressure is in intimate feedback with cardiac output and peripheral resistance, with relatively low blood pressure ... chronotropy can be beneficial when treating a variety of disease processes because lower heart rates represent lower cardiac ... The lower levels of vasopressin from the consumption of alcohol have been linked to ethanol acting as an antagonist to voltage- ... He named this herbal drug "Zarnab" and used it as a cardiac remedy. This was the first known use of a calcium channel blocker ...
... parasympathetic activation leads to decreased cardiac output via decrease in heart rate, resulting in a tendency to lower blood ... Sympathetic activation leads to an elevation of total peripheral resistance and cardiac output via increased contractility of ... The baroreflex can begin to act in less than the duration of a cardiac cycle (fractions of a second) and thus baroreflex ... Likewise, low blood pressure activates baroreceptors less and causes an increase in sympathetic tone via "disinhibition" (less ...
... however the common theme is that of a high cardiac output with a low or normal afterload. The output may be high due to the ... It is a cause of cardiac failure. In accordance with the Frank-Starling law of the heart, the myocardium contracts more ... Stretching of the myofibrils in cardiac muscle causes them to contract more powerfully due to a greater number of cross-bridges ... also causing right atrial volume overload Cardiac failure Frank-Starling law of the heart Preload (cardiology) Pressure ...
Learn about the normal output rate, how its measured, and causes of low cardiac output. ... Cardiac output is defined as the amount of blood your heart pumps. ... "Understanding Cardiac Output," "Why Measure Cardiac Output?". University of Mississippi Medical Center: "Control of Cardiac ... Low Output. If your heart doesnt pump enough blood to supply your body and tissues, it could signal heart failure. Low output ...
The Report Low Cardiac Output Syndrome Global Clinical Trials Review, H2, 2016 provides information on pricing, market analysis ... medical sciencemarket research reportsictequipmentchemicalsoutputlow cardiacsyndromelow cardiac outputlow cardiac output ... Low Cardiac Output Syndrome Global Clinical Trials Review, H2, 2016" provides an overview of Low Cardiac Output Syndrome ... Global Low Cardiac Output Syndrome Clinical Trials Review, H2, 2016. Press Release • Jan 05, 2017 06:20 EST ...
... low explanation free. What is Cardiac output, low? Meaning of Cardiac output, low medical term. What does Cardiac output, low ... Looking for online definition of Cardiac output, low in the Medical Dictionary? Cardiac output, ... cardiac output. (redirected from Cardiac output, low). Also found in: Dictionary, Thesaurus, Encyclopedia. output. [owt´poot] ... Cardiac output, low , definition of Cardiac output, low by Medical dictionary https://medical-dictionary.thefreedictionary.com/ ...
... "low cardiac output state." It is a syndrome evidenced by a low cardiac output or cardiac index (cardiac index ,2.4L/min/m2) ... Low cardiac output states after cardiac ischemia. Masse, L, Antonacci, B. "Low cardiac output syndrome: identification and ... Firstly the low-cardiac-output state needs to be recognized. Once this has occurred, then the cause of the low cardiac output ... As mentioned above, diagnosing a low-cardiac-output state is not enough - the cause of the low cardiac output has to be ...
Can levosimendan prevent postoperative low cardiac output syndrome?. Can levosimendan prevent postoperative low cardiac output ... Does a prophylactic levosimendan infusion reduce the incidence of postoperative low cardiac output syndrome in patients with ...
Systemic and regional hemodynamics in low, normal and high cardiac output borderline hypertension.. F H Messerli, J G De ... Systemic and regional hemodynamics in low, normal and high cardiac output borderline hypertension. ... Systemic and regional hemodynamics in low, normal and high cardiac output borderline hypertension. ... Systemic and regional hemodynamics in low, normal and high cardiac output borderline hypertension. ...
NIRS Predict Low Cardiac Output State in Neonates and Infants in Cardiac Surgery. The safety and scientific validity of this ... Does Near Infrared Spectroscopy Predict Low Cardiac Output State in Neonates and Infants Following Cardiac Surgery for ... Cardiac Output, Low. Cardiovascular Diseases. Cardiovascular Abnormalities. Congenital Abnormalities. Signs and Symptoms. ... for congenital heart disease are at great risk for experiencing life-threatening low cardiac output syndrome (LCOS) in the ...
An electrode for use in combination with a cardiac pacer for endocardial stimulation, having an electrode contact tip at the ... US4030508A - Low output electrode for cardiac pacing - Google Patents. Low output electrode for cardiac pacing Download PDF ... Low output electrode for cardiac pacing Applications Claiming Priority (1). Application Number. Priority Date. Filing Date. ... US05/655,156 1976-02-04 1976-02-04 Low output electrode for cardiac pacing Expired - Lifetime US4030508A (en) Priority ...
... ... pulmonary hypertension and a large left to right intracardiac shunt underwent surgical correction of a complex cardiac anomaly ...
Letter by Taegtmeyer and Khalaf Regarding Article, "Glucose-Insulin-Potassium Reduces the Incidence of Low Cardiac Output ... Letter by Taegtmeyer and Khalaf Regarding Article, "Glucose-Insulin-Potassium Reduces the Incidence of Low Cardiac Output ... Letter by Taegtmeyer and Khalaf Regarding Article, "Glucose-Insulin-Potassium Reduces the Incidence of Low Cardiac Output ... Letter by Taegtmeyer and Khalaf Regarding Article, "Glucose-Insulin-Potassium Reduces the Incidence of Low Cardiac Output ...
... and may require the use of inotropic drugs in patients with low cardiac output and evidence of organ hypoperfusion. However, ... and may require the use of inotropic drugs in patients with low cardiac output and evidence of organ hypoperfusion. However, ... Cardiac Output / physiology*. Cardiotonic Agents / adverse effects, pharmacology*. Clinical Trials as Topic. Digoxin / adverse ... to confirm and expand the effectiveness and safety of these agents in patients with acute heart failure and low cardiac output. ...
Pharmacologic Strategies with Afterload Reduction in Low Cardiac Output Syndrome After Pediatric Cardiac Surgery). Author(s): ... Pharmacologic Strategies with Afterload Reduction in Low Cardiac Output Syndrome After Pediatric Cardiac Surgery)", Current ... Pharmacologic Strategies with Afterload Reduction in Low Cardiac Output Syndrome After Pediatric Cardiac Surgery) ... Cardiac Stem Cell Regeneration in Metabolic Syndrome. Current Pharmaceutical Design. * Do Statins Beneficially or Adversely ...
Investigational Drugs with Clinical Trials for: Cardiac Output, Low. ➠ Get the DrugPatentWatch Daily Briefing. » See Plans and ...
A low cardiac output 2 or 6 hours after arrival in the ICU is associated with a high level of postoperative complication. Using ... Complicated patients had lower cardiac output and SVO2 values 2 and 6 hours after the arrival in ICU. In the logistic ... The benefit of routine measurement of cardiac output after cardiac surgery is still discussed. Some studies found no benefit of ... Clinical prediction of cardiac output is poor after cardiac surgery [3]. Clinicians also do not really know what value of ...
In conclusion, this study shows that low-dose bupivacaine (with sufentanil) combined with a low-dose infusion of phenylephrine ... A ) Cardiac output. ( B ) Systolic blood pressure. ( C ) Heart rate. ( D ) Stroke volume. Baseline is marked on the y label. SE ... A ) Cardiac output. ( B ) Systolic blood pressure. ( C ) Heart rate. ( D ) Stroke volume. Baseline is marked on the y label. SE ... A ) Cardiac output. ( B ) Systolic blood pressure. ( C ) Heart rate. ( D ) Stroke volume. Baseline is marked on the y label. SE ...
Artifactually Low Cardiac Outputs Resulting from a Communication Between the Proximal and Distal Lumens of an Edwards Pacing ... Artifactually Low Cardiac Outputs Resulting from a Communication Between the Proximal and Distal Lumens of an Edwards Pacing ... Artifactually Low Cardiac Outputs Resulting from a Communication Between the Proximal and Distal Lumens of an Edwards Pacing ... A. William Paulsen, Tim R. Valek; Artifactually Low Cardiac Outputs Resulting from a Communication Between the Proximal and ...
Management of the Low Cardiac Output Syndrome Following Surgery for Congenital Heart Disease. Author(s): Heather K. Chandler, ... Post-operative strategies that may be used to manage patients as risk for or in a state of low cardiac output include the use ... Post-operative strategies that may be used to manage patients as risk for or in a state of low cardiac output include the use ... Keywords: Acute kidney injury, heart failure, hemodynamic monitoring, low cardiac output, mechanical circulatory devices, ...
Increased cardiac output is related to dopamines direct inotropic effect on the myocardium. Increased cardiac output at low or ... In many instances the renal fraction of the total cardiac output has been found to increase. Increase in cardiac output ... Hypotension due to inadequate cardiac output can be managed by administration of low to moderate doses of dopamine HCl, which ... Static or decreased SVR associated with low or moderate movements in cardiac output is believed to be a reflection of ...
Low cardiac output can be simply defined as inability of the heart to pump enough blood to meet the metabolic requirements of ... Recognition and preemptive action against low cardiac output is one of the major challenges in cardiac surgery. ... Early treatment of low cardiac output can itself be therapeutic in preventing further low cardiac output !! ... Recognition and preemptive action against low cardiac output is one of the major challenges in cardiac surgery. Low cardiac ...
Cardiac Index in Children (Normal values). (Click on the image to enlarge) From Jim Locks Green Book (Cath book) 2nd edition. ...
... ... Browsing SAH Faculty and Staff Research by Subject "Cardiac Output, Low/ physiopathology". Archie Digital Collections. ...
... "low cardiac output state." It is a syndrome evidenced by a low cardiac output or cardiac index (cardiac index ,2.4L/min/m2) ... with evidence of organ dysfunction-for example, a high lactate or urine output ,0.5 ml/kg/hour.… ...
Cardiac Output, High Cardiac Output, Low Device: minimally invasive cardiac output system consisting of arterial line sensor ... Cardiac Output, Low. Cardiac Output, High. Heart Diseases. Cardiovascular Diseases. Signs and Symptoms. ... Device: minimally invasive cardiac output system consisting of arterial line sensor and cardiac output bedside monitor (device ... Using Minimally Invasive Cardiac Output Data vs. Standard Care for Patients Emergently Admitted to the Intensive Care Unit Who ...
Temporary pacing may also be used to optimise cardiac rate and rhythm.. Low cardiac output. is another common problem post ... decreased blood pressure and urine output. increased CVP excessive or abrupt cessation of SCC drainage.. Low cardiac output is ... COMPLICATIONS OF CARDIAC SURGER. Y. Haemorrhage. Low cardiac output. Hypertension. Arrhythmias. Stroke. Renal Failure. ... Low output despite adequate preload may indicate a problem with cardiac function, i.e. infarction or pre-existing impaired ...
Low Cardiac Output Drug: Hypertonic lactate Drug: Ringers lactate Phase 3 Detailed Description:. Prospective, randomized, open ... National cardiac Centre, Harapan Kita Hospital, Dept. of Anaesthesiology, Intensive Care Unit, Jakarta, Indonesia. ... National Cardiac Center, Department of Surgery and Intensive Care Unit, Harapan Kita Hospital. ...
Effect of low vs. high haemoglobin transfusion trigger on cardiac output in patients undergoing elective vascular surgery: Post ... RESULTS: The low-trigger resulted in a 7.1% lower mean intraoperative haemoglobin level (mean difference, -0.74 g/dL; P , .001 ... We evaluated whether inadequate increase in cardiac output (CO) following haemodilution explains reduction in ScO 2 . ... Lower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure. Publikation: Bidrag til tidsskrift › ...
Can levosimendan prevent postoperative low cardiac output syndrome?. Posted on 12 October 2017. 14 November 2017. by Sherry ... Does a prophylactic levosimendan infusion reduce the incidence of postoperative low cardiac output syndrome in patients with ... Posted in CD, icTV FootageTagged cardiac, congress, critical care, esicm, ICM, ICU, intensive care, JAMA, LICORN, LIVES, ...
... electrode adapted for implantation on or about the heart and for connection to a system for monitoring or stimulating cardiac ... Pediatric cardiac pacer system. US4030508 *. Feb 4, 1976. Jun 21, 1977. Vitatron Medical B.V.. Low output electrode for cardiac ... Cardiac Pacemakers, Inc.. Low energy defibrillation electrode. US5027813 *. Mar 5, 1990. Jul 2, 1991. Cardiac Pacemakers, Inc. ... Low threshold cardiac pacing electrodes. US4721115 *. Feb 27, 1986. Jan 26, 1988. Cardiac Pacemakers, Inc.. Diagnostic catheter ...
Low cardiac output syndrome. *Myocardial Infarction (MI). *Stroke. *AKI. *Arterial or venous thromboembolic events ... Subject needed non-emergency cardiac surgery with CPB.. * Types of cardiac operations permitted: complex/combined procedures ( ... Cardiac Surgery Cardiopulmonary Bypass Biological: AT-III (Human) Other: Placebo Phase 2 ... Surgical reexploration (return to operating room because of bleeding, tamponade, graft occlusion or other cardiac reason). ...
  • GlobalData's clinical trial report, Low Cardiac Output Syndrome Global Clinical Trials Review, H2, 2016" provides an overview of Low Cardiac Output Syndrome clinical trials scenario. (mynewsdesk.com)
  • This report provides top line data relating to the clinical trials on Low Cardiac Output Syndrome. (mynewsdesk.com)
  • The low-cardiac-output state can be thought of as the final common pathway of a multitude of diseases that affect the heart - it is a clinical syndrome. (psychiatryadvisor.com)
  • Can levosimendan prevent postoperative low cardiac output syndrome? (esicm.org)
  • Does a prophylactic levosimendan infusion reduce the incidence of postoperative low cardiac output syndrome in patients with impaired left ventricular function who are undergoing isolated or combined coronary artery bypass grafting surgery under cardiopulmonary bypass? (esicm.org)
  • Neonates and infants that have cardiac surgery with cardiopulmonary bypass (CPB) for congenital heart disease are at great risk for experiencing life-threatening low cardiac output syndrome (LCOS) in the first 24 hours after surgery. (clinicaltrials.gov)
  • Victor Bautista-Hernandez and Melvin C. Almodovar, "Editorial (Thematic Issue: Pharmacologic Strategies with Afterload Reduction in Low Cardiac Output Syndrome After Pediatric Cardiac Surgery)", Current Vascular Pharmacology (2016) 14: 3. (eurekaselect.com)
  • The purpose of this review is to discuss the management of the low cardiac output syndrome (LCOS) following surgery for congenital heart disease. (eurekaselect.com)
  • Heather K. Chandler and Roxanne Kirsch, "Management of the Low Cardiac Output Syndrome Following Surgery for Congenital Heart Disease", Current Cardiology Reviews (2016) 12: 107. (eurekaselect.com)
  • Dopamine HCl is indicated for the correction of hemodynamic imbalances present in the shock syndrome due to myocardial infarction , trauma , endotoxic septicemia , open-heart surgery, renal failure, and chronic cardiac decompensation as in congestive failure. (rxlist.com)
  • There is no clear consensus regarding the definition of low cardiac output syndrome (LCOS) or the follow-up of this patient group. (archivestsc.com)
  • Low cardiac output syndrome (LCOS) is a serious complication after cardiac surgery and is associated with significant morbidity and mortality . (bvsalud.org)
  • In this subset of patients, there is a higher risk of low cardiac output syndrome that increases the frequency of complications such as myocardial infarction, pulmonary impairment, or renal failure. (mhmedical.com)
  • While current management of low cardiac output syndrome includes use of inotropic agents or left ventricular assist devices, some studies have suggested that use of levosimendan, a calcium channel sensitizer, may help reduce occurrence of the syndrome. (mhmedical.com)
  • The present study is a randomized trial that investigated whether a 24-hour preoperative infusion of levosimendan in patients with left ventricular dysfunction undergoing CABG with bypass would reduce the risk of subsequent low cardiac output syndrome. (mhmedical.com)
  • Low cardiac output syndrome (LCOS) and maximum vasoactive inotropic score (VIS) have been used as surrogate markers for early postoperative outcomes in pediatric cardiac surgery. (elsevier.com)
  • Low cardiac output syndrome (LCOS) which features classic symptoms of hypotension, tachycardia, oliguria and poor peripheral perfusion after cardiac surgery is not rare in the immediate postoperative period, and usually requires high dose of inotropes and volume replacement. (springeropen.com)
  • Critical Illness-Related Corticosteroid Insufficiency should be suspected in patients with Low cardiac output syndrome after cardiac surgery especially when patients shows signs of persistent multi-organ failure such as high SOFA score or total bilirubin level. (springeropen.com)
  • Univariate and multivariate logistic regression for the prediction of low cardiac output syndrome after cardiac surgery with cardiopulmonary bypass. (medintensiva.org)
  • Sensibility, specificity and predictive values of Logistic Regression Model 1 and Model 2 to predict low cardiac output syndrome. (medintensiva.org)
  • To determine the predictive value of the inotropic score (IS) and vasoactive-inotropic score (VIS) in low cardiac output syndrome (LCOS) in children after congenital heart disease surgery involving cardiopulmonary bypass (CPB), and to establish whether mid-regional pro-adrenomedullin (MR-proADM) and cardiac troponin I (cTn-I), associated to the IS and VIS scores, increases the predictive capacity in LCOS. (medintensiva.org)
  • Methods: We performed a systematic review and meta-analysis (MEDLINE and Embase from inception until March 30, 2017), investigating whether levosimendan offers advantages compared with placebo in high-risk cardiac surgery patients, as defined by preoperative left ventricular ejection fraction (LVEF) ≤ 35% and/or low cardiac output syndrome (LCOS). (elsevier.com)
  • Shock (treatment)-The sympathomimetic agents (except isoproterenol) are indicated for the correction of hypotension, unresponsive to adequate fluid volume replacement, as part of shock syndrome caused by myocardial infarction, trauma, bacteremia {77} , open-heart surgery, renal failure, chronic cardiac decompensation, drug overdose {65} {76} , or other major systemic illness {70} . (drugs.com)
  • The LEVO-CTS trial is a double-blind, randomized, placebo-controlled study that is evaluating the use of levosimendan administered before and during cardiac surgery to reduce the incidence of low cardiac output syndrome and associated morbidity and mortality. (businesswire.com)
  • The Company owns the North American rights to develop and commercialize levosimendan, and the United States Food and Drug Administration (FDA) has granted Fast Track status for levosimendan for the reduction of morbidity and mortality in cardiac surgery patients at risk for developing Low Cardiac Output Syndrome (LCOS). (businesswire.com)
  • Given this lack of a clinical definition, the aim of this study was to use a LCOS score (LCOSs) similar to the low cardiac output score previously presented in the literature and evaluate the relationship between a high LCOSs and poor clinical outcome. (archivestsc.com)
  • The objective of this study was to determine the associations between LCOS and maximum VIS with clinical outcomes in neonatal cardiac surgery. (elsevier.com)
  • We aimed to investigate clinical features of CIRCI in patients with LCOS after cardiac surgery and assessed the efficacy of steroid use in this subset of patients. (springeropen.com)
  • We retrospectively reviewed the patients who were suspected as combined CIRCI in the setting of LCOS after cardiac surgery between February 2010 and September 2014. (springeropen.com)
  • This swelling or congestion of the tissue spaces (fluid overload) is the reason why heart failure is also known as congestive heart (cardiac) failure. (healthhype.com)
  • A patient with preoperative pulmonary hypertension and a large left to right intracardiac shunt underwent surgical correction of a complex cardiac anomaly and required extracorporeal life support for unexplained ventricular dysfunction following the procedure. (ovid.com)
  • CONCLUSION: Vascular surgical patients exposed to restrictive RBC transfusion elicit the expected increase in CO making it unlikely that their potentially limited cardiac capacity explains the associated ScO 2 decrease. (regionh.dk)
  • This trial was designed as a randomized, double-blind, 2-arm, parallel-group, placebo-controlled study within thirteen participating cardiac surgical centers. (mhmedical.com)
  • Argon gas is the coldest ablation source commercially available for the surgical treatment of cardiac arrhythmias. (medtronic.com)
  • This study is designed to determine if point-of-care washing of allogeneic Leukocyte-Reduced Red Blood Cells reduces pulmonary complications when compared to standard-of-care Leukocyte-Reduced Red Blood Cells in a cardiac surgical population. (mayo.edu)
  • This new edition maintains the high standards established in the first edition: insightful descriptions of various cardiac surgical procedures illuminated by clear, brilliant illustrations. (indigo.ca)
  • The study population consists of patients over 18 years of age, and the types of operations recorded were: coronary artery bypass graft (CABG), mitral valve, aortic valve (either conventional or transcatheter), surgical correction of atrial fibrillation, cardiac transplantation, mechanical circulatory support and congenital heart diseases in adults. (scielo.br)
  • The purpose of this study is to determine the safety and effectiveness of human-derived antithrombin III (AT-III [Human]) supplementation prior to high-risk, non-emergency, cardiac surgery with cardiopulmonary bypass (CPB). (clinicaltrials.gov)
  • Overall, the results of this study suggest levosimendan does not help reduce the risk of low cardiac output failure in patients with left ventricular dysfunction that are undergoing CABG with cardiopulmonary bypass. (mhmedical.com)
  • Eligible patients included those with reduced left ventricular ejection fraction (40% or lower), undergoing CABG surgery with cardiopulmonary bypass alone or combined with valve surgery. (mhmedical.com)
  • Neonates (n = 76) undergoing corrective or palliative cardiac operations requiring cardiopulmonary bypass were prospectively enrolled. (elsevier.com)
  • Spontaneous echo contrast was present in all cardiac chambers in all seven bears during hibernation, despite the absence of atrial arrhythmias and valvular disease. (forskningsdatabasen.dk)
  • Also, cardiac arrhythmias induced by the sympathomimetic agents may be more likely to occur in patients with myocardial infarction. (drugs.com)
  • Sometimes, sepsis , your body's response to blood infections that can lead to a dangerous drop in blood pressure and organ failure, can cause high cardiac output. (webmd.com)
  • Systemic and regional hemodynamics in low, normal and high cardiac output borderline hypertension. (ahajournals.org)
  • The study's aim was to find out whether treating blood pressure to lower the systolic number to 120 mm Hg or less was superior to the standard target of 140 mm Hg or less. (lifechangingcarehouston.com)
  • Systolic pulmonary artery pressure, cardiac output, and peripheral arterial oxygen saturation at rest and during assessment of maximum exercise capacity on cycle ergometry 1) while breathing a hypoxic gas mixture with 10% fraction of inspired oxygen at low altitude (Giessen) and 2) at high altitude (the Mount Everest base camp). (annals.org)
  • The ability to use noninvasive, continuous monitoring for overall perfusion and cardiac output will allow better and earlier therapy for neonates and infants following cardiac surgery. (clinicaltrials.gov)
  • The objective of this study was to draw attention to the potential use of a common language in the care of critical pediatric patients undergoing cardiac surgery with a previously defined scoring method that includes parameters indicating poor perfusion in the patient. (archivestsc.com)
  • {20} This assessment may include hemodynamic status, mental status, urine output, and other measures of tissue perfusion. (drugs.com)
  • Systemic hypotension is common in very low birthweight preterm infants but the nature of the precipitating cause may be unclear. (biomedsearch.com)
  • We present a case of a preterm infant with systemic hypotension and low cardiac output secondary to a large transatrial shunt induced by a malpositioned umbilical venous catheter. (biomedsearch.com)
  • Low blood pressure, also called hypotension, is usually defined as having a blood pressure low enough to cause dizziness, blurry vision or fainting. (columbiatribune.com)
  • Left ventricular Cardiac Output (CO) was measured by a duplex scanner with pulsed Doppler and color flow mapping echocardiography in the first 48 hours of life. (gerboni.net)
  • In particular, in critically ill patients, TTE is daily used to track changes in cardiac output, which are assessed from relative changes in the velocity-time integral (VTI) of the left ventricular outflow tract. (biomedcentral.com)
  • Postoperative ventricular failure with low cardiac output was the most common indication of ECMO initiation. (frontiersin.org)
  • This amendment changes the inclusion criteria for the trial to cardiac surgery patients with a left ventricular ejection fraction (LVEF) of ≤ 35% undergoing a coronary artery bypass grafting (CABG) procedure, CABG and an aortic valve procedure, and CABG and/or a mitral valve procedure. (businesswire.com)
  • Invasive monitoring gives continuous measurements of blood pressure, systemic vascular resistance (SVR), and cardiac output (CO) and may increase our understanding of hemodynamic changes during spinal anesthesia and cesarean delivery. (asahq.org)
  • This was a prospective, randomized, double-blind, parallel-group, placebo-controlled study comparing the hemodynamic effects of a high dose of spinal anesthesia with isobaric bupivacaine 10 mg (B10) with a low dose of 7 mg (B7), and the prophylactic effect of 0.25 μg · kg −1 · min −1 intravenous phenylephrine infusion (Phenyl) with placebo. (asahq.org)
  • The purpose of this study is to evaluate if the continuous availability of minimally invasive cardiac output data during treatment in the intensive care unit (ICU) for hemodynamic instability, in comparison to standard of care will shorten the time needed to stabilize the patient. (clinicaltrials.gov)
  • Does Near Infrared Spectroscopy Predict Low Cardiac Output State in Neonates and Infants Following Cardiac Surgery for Congenital Heart Disease? (clinicaltrials.gov)
  • Structural defects associated with congenital heart disease primarily cause cardiac shunts or obstruction to blood flow. (healthhype.com)
  • 8 Low Cardiac Output: Pathophysiology and Treatment. (indigo.ca)
  • The European Society of Cardiology (ESC) defines cardiogenic shock as "evidence of tissue hypoperfusion induced by cardiac dysfunction after correction of preload. (psychiatryadvisor.com)
  • The underlying cause of the myocardial dysfunction may be primarily cardiac or extracardiac. (psychiatryadvisor.com)
  • Broadly, cardiac dysfunction can result from any cardiac structural disorder or functional disorder that disrupts cardiac filling or emptying. (psychiatryadvisor.com)
  • Valvular dysfunction increases cardiac workload , i.e., regurgitation forces the heart to pump increased volumes and stenosis necessitates the generation of increased pressure to overcome increased resistance to flow. (prezi.com)
  • Introduction Despite technical improvements in congenital heart surgery mortality as A-674563 a result of cardiac dysfunction after corrective surgery remains a serious problem. (flora2world.com)
  • stroke output stroke volume . (thefreedictionary.com)
  • It is equal to the stroke volume-the output per beat-multiplied by the number of beats per minute. (thefreedictionary.com)
  • Various techniques have been introduced for monitoring cardiac output, stroke volume, or their surrogates. (clinicaltrials.gov)
  • Techniques are described for estimating a rate of blood flow from a heart, such as a stroke volume or a cardiac output, as a function of a pressure in the heart. (google.com)
  • The pressure monitor may calculate the stroke volume or cardiac output using the velocity-time integral. (google.com)
  • The pressure monitor may control a delivery of therapy by an implantable medical device as a function of the stroke volume or cardiac output. (google.com)
  • Cardiac output is equal to heart rate multiplied by stroke volume (the volume of blood ejected with each heartbeat). (healthtap.com)
  • Cardiac output is the product of heart rate in stroke volume. (healthtap.com)
  • This is a product of stroke volume or cc's of blood per beat times the heart rate so cardiac output increases with either an increase in stroke volume or heart rate or both. (healthtap.com)
  • In a new two-pronged study being presented at the American College of Cardiology's 68th Annual Scientific Session, people who spent less time watching TV and regularly ate an energy-rich breakfast showed significantly less plaque and stiffness in their arteries, indicating a lower chance of developing heart disease or suffering a stroke. (news-medical.net)
  • Cardiac output in turn depends on the interrelated factors of heart rate (HR) and stroke volume (SV)--that is, CO=HR*SV. (bmj.com)
  • Cardiac index (liters per minute per meter squared) was quantified from echocardiography. (nih.gov)
  • Acute heart failure with low cardiac output: can we develop a short-term inotropic agent that does not increase adverse events? (biomedsearch.com)
  • Acute heart failure represents an increasingly common cause of hospitalization, and may require the use of inotropic drugs in patients with low cardiac output and evidence of organ hypoperfusion. (biomedsearch.com)
  • Increased cardiac output is related to dopamine's direct inotropic effect on the myocardium . (rxlist.com)
  • The aims of this study were to determine the agreement between pulmonary artery thermodilution (PA-TD), transpulmonary thermodilution (TP-TD) and the pulse contour method, and to test the ability of the pulse contour method to track changes in cardiac output. (wiley.com)
  • There is a continuum from a low-cardiac-output state to cardiogenic shock. (psychiatryadvisor.com)
  • Persistently low cardiac output predicts high mortality in newborns with cardiogenic shock. (gerboni.net)
  • Increase in cardiac output has been associated with either static or decreased systemic vascular resistance (SVR). (rxlist.com)
  • Increase in cardiac output produced by dopamine is not associated with substantial decreases in systemic vascular resistance as may occur with isoproterenol. (rxlist.com)
  • Let us start with blood pressure: Ohm's law has been adapted to demonstrate that blood pressure (BP) is the product of cardiac output (CO) and systemic vascular resistance (SVR)--that is, BP=CO*SVR. (bmj.com)
  • Therefore a low blood pressure can be due to a low cardiac output (low flow) or reduced systemic vascular resistance (vasodilatation) or both. (bmj.com)
  • Further investigations are needed to confirm and expand the effectiveness and safety of these agents in patients with acute heart failure and low cardiac output. (biomedsearch.com)
  • Not until acute normovolemic hemodilution studies were performed were we able to progressively appraise how well patients could tolerate lower levels of hemoglobin without significant adverse outcomes. (ccjm.org)
  • Subsequently, studies proved that healthy, elderly, and stable cardiac patients can tolerate acute anemia with normal cardiovascular response. (ccjm.org)
  • Cardiac output is commonly measured by the thermodilution technique. (thefreedictionary.com)
  • 35%). METHODS: Thermodilution cardiac output measurements obtained with three 5-mL and three 10-mL (randomly ordered) iced injectates in 50 patients with low ejection fraction were averaged if the measurements were within 10% of the median. (aacnjournals.org)
  • For this purpose, Pulsion Medical Systems elected to use the bolus transpulmonary thermodilution (TP-TD) cardiac output. (wiley.com)
  • The greater variability of measurements obtained with a 5-mL injectate suggests that more measurements, and thus more time, are needed to measure cardiac output accurately. (aacnjournals.org)
  • Currently, a practical, precise, minimally invasive way to measure cardiac output or heart function in children undergoing surgery does not exist. (news-medical.net)
  • After cardiac surgery, all subjects will have EQUANOX Advance 8004CB sensors applied to peripheral sites (left and right calf and side of abdomen). (clinicaltrials.gov)
  • Static or decreased SVR associated with low or moderate movements in cardiac output is believed to be a reflection of differential effects on specific vascular beds with increased resistance in peripheral beds (e.g., femoral ) and concomitant decreases in mesenteric and renal vascular beds. (rxlist.com)
  • High-output heart failure is a heart condition that occurs when the cardiac output is higher than normal due to increased peripheral demand. (wikipedia.org)
  • Severe low oxygen can cause muscles to twitch but this is usually in elderly people with peripheral vascular disease or significant cardio-pulmonary disease. (healthtap.com)
  • In a physiologic model, increased blood pressure or "hypertension" or increased "afterload" tends to decrease cardiac output . (healthtap.com)
  • In a complete animal or human model, there are various reflexes that work to maintain cardiac output in the face of increased afterload but they shouldn't cause an increase in cardiac output relative to the baseline. (healthtap.com)
  • {04} {28} It is also used in hypotensive states following sympathectomy, or following overdose with ganglionic blocking agents, antiadrenergic agents, or other medications that lower blood pressure in the treatment of hypertension. (drugs.com)
  • How does hypertension increase cardiac output? (healthtap.com)
  • This was a secondary retrospective analysis of a prospective randomized trial, and the setting was a pediatric cardiac intensive care unit in a tertiary care children's hospital. (elsevier.com)
  • In the logistic regression analysis, a reduced cardiac index at 2 and 6 hours after admission in the ICU had the strongest independent predictive value for postoperative complication. (biomedcentral.com)
  • Background: Previous studies have shown beneficial effects of levosimendan in high-risk patients undergoing cardiac surgery. (elsevier.com)
  • Edwards Lifesciences has developed a new algorithm for the determination of cardiac output using arterial pressure data. (clinicaltrials.gov)
  • The FloTrac™ system, which includes the FloTrac™ sensor and Vigileo™ monitor, is utilized to capture the arterial pressure-based cardiac output measurement, which will be hereinafter referred to as APCO (Arterial Pressure Cardiac Output). (clinicaltrials.gov)
  • Finally, in patients with heart rates below 60 beats/min or a cardiac index of less than 2.5 l/min/m 2 , atrial pacing was started and the haemodynamic consequences were monitored with the PA-TD and pulse contour methods. (wiley.com)
  • The changes in cardiac output with atrial pacing were in the same direction and of the same magnitude in 15 of the 16 patients. (wiley.com)
  • decreased cardiac output a nursing diagnosis accepted by the North American Nursing Diagnosis Association, defined as a state in which inadequate blood is pumped by the heart to meet the metabolic demands of the body. (thefreedictionary.com)
  • The aim of the present study was to verify whether the commonly accepted lower value of cardiac index of 2.2 l/min/m 2 [ 4 ] at arrival in the ICU was a good predictor of complications after cardiac surgery. (biomedcentral.com)
  • MORRISVILLE, N.C.--( BUSINESS WIRE )--Tenax Therapeutics, Inc. (NASDAQ: TENX), a specialty pharmaceutical company focused on identifying, developing and commercializing products for the critical care market, today provided a detailed clinical progress update for the ongoing development of its lead candidate levosimendan in cardiac surgery and septic shock. (businesswire.com)
  • Low output also could happen after you've lost too much blood, had a severe infection called sepsis , or had severe heart damage. (webmd.com)
  • This includes most common respiratory alkalemia (a higher than normal blood pH from low carbon dioxide levels in the blood), which in turn is caused by any hyperventilation (such as may result from sepsis, fever, pain, anxiety, drug withdrawal, and many other causes). (wikipedia.org)
  • When measuring output for a patient record, the volume of urine, drainage from tubes, vomitus, and any other measurable liquid should be recorded. (thefreedictionary.com)
  • urinary output the amount of urine secreted by the kidneys. (thefreedictionary.com)
  • Dopamine HCl may also increase urine flow in patients whose output is within normal limits and thus may be of value in reducing the degree of pre-existing fluid accumulation. (rxlist.com)
  • A patient on the coronary care unit has developed low blood pressure and poor urine output. (bmj.com)
  • Decreased urine output so that the blood volume can be increased. (healthhype.com)
  • Water retention due to reduce urine output (explained above) causes fluid in the lungs (pulmonary edema) and around the lungs (pleural effusion) which affects gas exchange. (healthhype.com)
  • More than eight of ten patients believed to be in PEA have synchronous cardiac wall motion, and over 40% have a measurable aortic pressure. (blogspot.com)
  • Thus graft flow measurements, peroperative TEE and pressure measurements etc all can indicate an important residual problem which if left can lead to progressive low output. (fandom.com)
  • Clinicians must weigh the benefit of minimizing fluid volume used against the potential decreased reliability of cardiac output measurements. (aacnjournals.org)
  • The precision of cardiac output measurements with PA-TD and TP-TD was very similar. (wiley.com)
  • Post-operatively, cardiac output measurements with the PA-TD and pulse contour methods did not agree, but the pulse contour method reliably tracked pacing-induced changes in cardiac output. (wiley.com)
  • Bridge to heart A-674563 transplantation should be considered if there is no improvement in cardiac function to avoid irreversible multiorgan failure (MFO). (flora2world.com)
  • PMID 11242561 Causes of High-Output Heart Failure Healthwise Staff of WebMD. (wikipedia.org)
  • In heart failure, the cardiac output is reduced and as the condition progresses, the body's tissues become filled with fluid. (healthhype.com)
  • It is important to be familiar with the components and physiology of cardiac output in order to understand heart failure. (healthhype.com)
  • None of the compensatory mechanisms can sustain the cardiac output over a prolong period of time and will eventually cause further damage to the heart and lead to heart failure. (healthhype.com)
  • Factors that could lead to changes in a patient's functional capacities because of decreased cardiac output might include physical exercise of a type or intensity that the patient cannot tolerate because of diminished oxygen supply, ingestion of large meals that place an added workload on the heart, obesity, retention of fluid (edema), hypovolemia or hypervolemia, emotional stress, and smoking. (thefreedictionary.com)
  • An electrode for use in combination with a cardiac pacer for endocardial stimulation, having an electrode contact tip at the distal end which has an annular shape with rounded edges for providing a very small stimulating surface, with the largest possible area of such surface in optimal position for direct contact with the heart muscle. (google.com)
  • This invention relates to electrodes, or catheters, and, more particularly, to unipolar electrodes adapted for use in combination with cardiac pacers for low power drain stimulation of a patient's heart. (google.com)
  • Low cardiac output can be simply defined as inability of the heart to pump enough blood to meet the metabolic requirements of the body . (fandom.com)
  • A single-pass endocardial lead electrode adapted for implantation on or about the heart and for connection to a system for monitoring or stimulating cardiac activity including a lead body with a circumferential outer surface. (google.com)
  • History Low cardiac output (LCO) after corrective surgery remains a serious complication in pediatric congenital heart diseases (CHD). (flora2world.com)
  • Diastolic blood pressures measures your blood pressure when your heart is relaxing and is the "lower number" of your blood pressure reading. (columbiatribune.com)
  • Cardiac output is a measurement of the amount of blood a person's heart can pump out during a set amount of time. (healthtap.com)
  • The cardiac output is the volume of blood per minute pumped by the heart. (healthtap.com)
  • Thus, an increase in heart rate results in an increase in cardiac output. (healthtap.com)
  • Acetylcholine neurotransmission has an inhibitory effect on the heart, which lowers heart rate thereby decreasing cardiac output . (healthtap.com)
  • Cardiac output is related to the heart rate , and volume of blood the heart can pump with each heart beat. (healthtap.com)
  • A low cardiac output occurs when the pump function of the heart is compromised by an event such as a heart attack or when the blood volume is reduced by and event such as dehydration , or bleeding. (healthtap.com)
  • If oxygen is very low, the heart may not pump as well. (healthtap.com)
  • By slowly bringing your heart rate back down, you can avoid blood pooling in the lower extremities because the muscles of your legs are still contracting and contributing to venous return. (livestrong.com)
  • However, after a long period of time, the body's compensatory mechanisms to maintain a normal cardiac output may cause irreversible damage to the heart. (healthhype.com)
  • Cardiac output is the amount of blood pushed out of the heart over a period of time. (healthhype.com)
  • This is also determined by the strength of the heart muscle to force out blood (myocardial contractility) and the elasticity of the arteries, particularly the aorta , which need to stretch and recoil to keep blood flowing (Windkessel effect discussed under cardiac output). (healthhype.com)
  • Most congenital heart defects arise due to genetic abnormalities but a disturbance of any other factor that plays a role in cardiac development may also be responsible. (healthhype.com)
  • I recently had a stress echo which found that with exercise my heart did not squeeze properly which looked like balanced cardiac disease to my cardiologist. (medhelp.org)
  • Is a low-fat diet really that heart healthy after all? (medhelp.org)
  • How to lower your heart attack risk. (medhelp.org)
  • Clinical studies that have followed older individuals over many years have consistently demonstrated that chronically low blood pressure increases the risk of age-related cognitive decline. (columbiatribune.com)
  • Prior to surgery patients undergo an Echo and Angiogram to accurately assess cardiac function. (prezi.com)
  • Our objective was to assess cardiac function associated with metabolic depression in the hibernating vs. active states in free-ranging Scandinavian brown bears. (forskningsdatabasen.dk)
  • To assess cross-sectionally whether lower cardiac index relates to lower resting cerebral blood flow (CBF) and cerebrovascular reactivity (CVR) among older adults. (nih.gov)
  • Levosimendan reduces the need for RRT after high-risk cardiac surgery. (elsevier.com)
  • Based on historical clinical results and the recommendation of our trial steering committee, including physicians with significant clinical experience using levosimendan, this broader cardiac surgery patient population should benefit from our drug candidate. (businesswire.com)
  • However, in some patients the dominant manifestations are of reduced cardiac output and tissue hypoperfusion with or without congestion. (psychiatryadvisor.com)
  • Surgeons accustomed to creating cardiac tissue ablations with a clamp can use argon-powered cryoablation in a familiar delivery system. (medtronic.com)
  • Clinicians also do not really know what value of cardiac output is necessary after cardiac surgery. (biomedcentral.com)
  • High output also can happen when your body lacks enough oxygen-carrying red blood cells, a condition called anemia . (webmd.com)
  • Could low oxygen (decreased lung expansion) decreases cardiac output? (healthtap.com)
  • electrolyte imbalance, hypoxia (low blood oxygen levels), and elevated liver enzymes . (medicinenet.com)
  • Insufficient supply of oxygen and nutrients to the cells results in fatigue (low energy levels). (healthhype.com)
  • Does bronchiolitis cause low oxygen saturation? (healthtap.com)
  • Can sleep apnea cause low oxygen level? (healthtap.com)
  • Both obstructive and central sleep apnea can lead to a decreased gas exchange in the lung through either decreased airflow or disturbed ventilation during the sleep and subsequently result in low oxygen level in blood. (healthtap.com)
  • How much does a low oxygen saturation level affect judgment? (healthtap.com)
  • A low oxygen saturation definitely affects judgment. (healthtap.com)
  • How much can a low venous oxygen saturation affect judgement? (healthtap.com)
  • Low oxygen levels can affect someone's judgment and arousal. (healthtap.com)
  • I have met plenty of people with very low oxygen levels and can act and feel fine. (healthtap.com)
  • Will lower oxygen level. (healthtap.com)
  • Why would patients with COPD be given low flow concentration (1-2l/min) supplemental oxygen? (healthtap.com)
  • At this point, the body is not getting enough energy, the blood oxygen level is low. (healthtap.com)
  • Oxygen is used at the lowest amount that would achieve the goal. (healthtap.com)
  • Is an oxygen saturation of 69% when sleeping dangerously low? (healthtap.com)
  • Why should patients with COPD be given low flow concentration supplemental oxygen? (healthtap.com)
  • We measured cardiac output noninvasively using estimates of hemodynamics obtained by pulsed wave Doppler echocardiography and 2D imaging. (forskningsdatabasen.dk)
  • CONCLUSION: Free-ranging brown bears demonstrate hemodynamics comparable to humans during active state, whereas during hibernation, we documented extremely low-flow hemodynamics. (forskningsdatabasen.dk)