A method of computed tomography that uses radionuclides which emit a single photon of a given energy. The camera is rotated 180 or 360 degrees around the patient to capture images at multiple positions along the arc. The computer is then used to reconstruct the transaxial, sagittal, and coronal images from the 3-dimensional distribution of radionuclides in the organ. The advantages of SPECT are that it can be used to observe biochemical and physiological processes as well as size and volume of the organ. The disadvantage is that, unlike positron-emission tomography where the positron-electron annihilation results in the emission of 2 photons at 180 degrees from each other, SPECT requires physical collimation to line up the photons, which results in the loss of many available photons and hence degrades the image.
Discrete concentrations of energy, apparently massless elementary particles, that move at the speed of light. They are the unit or quantum of electromagnetic radiation. Photons are emitted when electrons move from one energy state to another. (From Hawley's Condensed Chemical Dictionary, 11th ed)
Organic compounds that contain technetium as an integral part of the molecule. These compounds are often used as radionuclide imaging agents.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
Tomography using radioactive emissions from injected RADIONUCLIDES and computer ALGORITHMS to reconstruct an image.
A gamma-emitting RADIONUCLIDE IMAGING agent used in the evaluation of regional cerebral blood flow and in non-invasive dynamic biodistribution studies and MYOCARDIAL PERFUSION IMAGING. It has also been used to label leukocytes in the investigation of INFLAMMATORY BOWEL DISEASES.
Compounds that contain the radical R2C=N.OH derived from condensation of ALDEHYDES or KETONES with HYDROXYLAMINE. Members of this group are CHOLINESTERASE REACTIVATORS.
Unstable isotopes of thallium that decay or disintegrate emitting radiation. Tl atoms with atomic weights 198-202, 204, and 206-210 are thallium radioisotopes.
Compounds that are used in medicine as sources of radiation for radiotherapy and for diagnostic purposes. They have numerous uses in research and industry. (Martindale, The Extra Pharmacopoeia, 30th ed, p1161)
An imaging technique using compounds labelled with short-lived positron-emitting radionuclides (such as carbon-11, nitrogen-13, oxygen-15 and fluorine-18) to measure cell metabolism. It has been useful in study of soft tissues such as CANCER; CARDIOVASCULAR SYSTEM; and brain. SINGLE-PHOTON EMISSION-COMPUTED TOMOGRAPHY is closely related to positron emission tomography, but uses isotopes with longer half-lives and resolution is lower.
An amphetamine analog that is rapidly taken up by the lungs and from there redistributed primarily to the brain and liver. It is used in brain radionuclide scanning with I-123.
The first artificially produced element and a radioactive fission product of URANIUM. Technetium has the atomic symbol Tc, atomic number 43, and atomic weight 98.91. All technetium isotopes are radioactive. Technetium 99m (m=metastable) which is the decay product of Molybdenum 99, has a half-life of about 6 hours and is used diagnostically as a radioactive imaging agent. Technetium 99 which is a decay product of technetium 99m, has a half-life of 210,000 years.
Unstable isotopes of iodine that decay or disintegrate emitting radiation. I atoms with atomic weights 117-139, except I 127, are radioactive iodine isotopes.
The circulation of blood through the BLOOD VESSELS of the BRAIN.
A technetium imaging agent used to reveal blood-starved cardiac tissue during a heart attack.
A heavy, bluish white metal, atomic number 81, atomic weight [204.382; 204.385], symbol Tl.
Unstable isotopes of xenon that decay or disintegrate emitting radiation. Xe atoms with atomic weights 121-123, 125, 127, 133, 135, 137-145 are radioactive xenon isotopes.
A radionuclide imaging agent used primarily in scintigraphy or tomography of the heart to evaluate the extent of the necrotic myocardial process. It has also been used in noninvasive tests for the distribution of organ involvement in different types of amyloidosis and for the evaluation of muscle necrosis in the extremities.
The hollow, muscular organ that maintains the circulation of the blood.
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
N-methyl-8-azabicyclo[3.2.1]octanes best known for the ones found in PLANTS.
Analogs or derivatives of AMPHETAMINE. Many are sympathomimetics and central nervous system stimulators causing excitation, vasopressin, bronchodilation, and to varying degrees, anorexia, analepsis, nasal decongestion, and some smooth muscle relaxation.
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
Tomography using single-photon emitting RADIONUCLIDES to create images that are captured in times corresponding to various points in the cardiac cycle.
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
Imaging methods that result in sharp images of objects located on a chosen plane and blurred images located above or below the plane.
The creation and display of functional images showing where the blood is flowing into the MYOCARDIUM by following over time the distribution of tracers injected into the blood stream.
Any visual display of structural or functional patterns of organs or tissues for diagnostic evaluation. It includes measuring physiologic and metabolic responses to physical and chemical stimuli, as well as ultramicroscopy.
One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
A technique of inputting two-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer.
Organic compounds that contain phosphorus as an integral part of the molecule. Included under this heading is broad array of synthetic compounds that are used as PESTICIDES and DRUGS.
Computer-based representation of physical systems and phenomena such as chemical processes.
Controlled physical activity which is performed in order to allow assessment of physiological functions, particularly cardiovascular and pulmonary, but also aerobic capacity. Maximal (most intense) exercise is usually required but submaximal exercise is also used.
Devices or objects in various imaging techniques used to visualize or enhance visualization by simulating conditions encountered in the procedure. Phantoms are used very often in procedures employing or measuring x-irradiation or radioactive material to evaluate performance. Phantoms often have properties similar to human tissue. Water demonstrates absorbing properties similar to normal tissue, hence water-filled phantoms are used to map radiation levels. Phantoms are used also as teaching aids to simulate real conditions with x-ray or ultrasonic machines. (From Iturralde, Dictionary and Handbook of Nuclear Medicine and Clinical Imaging, 1990)
A serotonin antagonist with limited antihistaminic, anticholinergic, and immunosuppressive activity.
A class of compounds of the type R-M, where a C atom is joined directly to any other element except H, C, N, O, F, Cl, Br, I, or At. (Grant & Hackh's Chemical Dictionary, 5th ed)
The use of combination of imaging techniques or platforms (e.g., MRI SCAN and PET SCAN) encompassing aspects of anatomical, functional, or molecular imaging methods.
Striated muscle cells found in the heart. They are derived from cardiac myoblasts (MYOBLASTS, CARDIAC).
The compound is given by intravenous injection to do POSITRON-EMISSION TOMOGRAPHY for the assessment of cerebral and myocardial glucose metabolism in various physiological or pathological states including stroke and myocardial ischemia. It is also employed for the detection of malignant tumors including those of the brain, liver, and thyroid gland. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1162)
Sodium chloride-dependent neurotransmitter symporters located primarily on the PLASMA MEMBRANE of dopaminergic neurons. They remove DOPAMINE from the EXTRACELLULAR SPACE by high affinity reuptake into PRESYNAPTIC TERMINALS and are the target of DOPAMINE UPTAKE INHIBITORS.
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Unstable isotopes of indium that decay or disintegrate emitting radiation. In atoms with atomic weights 106-112, 113m, 114, and 116-124 are radioactive indium isotopes.
The part of the cerebral hemisphere anterior to the central sulcus, and anterior and superior to the lateral sulcus.
An imaging method using LASERS that is used for mapping subsurface structure. When a reflective site in the sample is at the same optical path length (coherence) as the reference mirror, the detector observes interference fringes.
Disorders of the centrally located thalamus, which integrates a wide range of cortical and subcortical information. Manifestations include sensory loss, MOVEMENT DISORDERS; ATAXIA, pain syndromes, visual disorders, a variety of neuropsychological conditions, and COMA. Relatively common etiologies include CEREBROVASCULAR DISORDERS; CRANIOCEREBRAL TRAUMA; BRAIN NEOPLASMS; BRAIN HYPOXIA; INTRACRANIAL HEMORRHAGES; and infectious processes.
Microsurgical revascularization to improve intracranial circulation. It usually involves joining the extracranial circulation to the intracranial circulation but may include extracranial revascularization (e.g., subclavian-vertebral artery bypass, subclavian-external carotid artery bypass). It is performed by joining two arteries (direct anastomosis or use of graft) or by free autologous transplantation of highly vascularized tissue to the surface of the brain.
Radioactive substances added in minute amounts to the reacting elements or compounds in a chemical process and traced through the process by appropriate detection methods, e.g., Geiger counter. Compounds containing tracers are often said to be tagged or labeled. (Hawley's Condensed Chemical Dictionary, 12th ed)
A gamma-emitting radionuclide imaging agent used primarily in skeletal scintigraphy. Because of its absorption by a variety of tumors, it is useful for the detection of neoplasms.
The flow of BLOOD through or around an organ or region of the body.
Isotopes that exhibit radioactivity and undergo radioactive decay. (From Grant & Hackh's Chemical Dictionary, 5th ed & McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Elements of limited time intervals, contributing to particular results or situations.
A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
Deficient development or degeneration of a portion of the VERTEBRA, usually in the pars interarticularis (the bone bridge between the superior and inferior facet joints of the LUMBAR VERTEBRAE) leading to SPONDYLOLISTHESIS.
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
The span of viability of a tissue or an organ.
Electronic instruments that produce photographs or cathode-ray tube images of the gamma-ray emissions from organs containing radionuclide tracers.
A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
Determination of the energy distribution of gamma rays emitted by nuclei. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
A gamma-emitting radionuclide imaging agent used for the diagnosis of diseases in many tissues, particularly in cardiovascular and cerebral circulation.
Improvement of the quality of a picture by various techniques, including computer processing, digital filtering, echocardiographic techniques, light and ultrastructural MICROSCOPY, fluorescence spectrometry and microscopy, scintigraphy, and in vitro image processing at the molecular level.
Radiography of the vascular system of the heart muscle after injection of a contrast medium.
Dominance of one cerebral hemisphere over the other in cerebral functions.
The use of molecularly targeted imaging probes to localize and/or monitor biochemical and cellular processes via various imaging modalities that include RADIONUCLIDE IMAGING; ULTRASONOGRAPHY; MAGNETIC RESONANCE IMAGING; FLUORESCENCE IMAGING; and MICROSCOPY.
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
The process of generating three-dimensional images by electronic, photographic, or other methods. For example, three-dimensional images can be generated by assembling multiple tomographic images with the aid of a computer, while photographic 3-D images (HOLOGRAPHY) can be made by exposing film to the interference pattern created when two laser light sources shine on an object.
The circulation of blood through the CORONARY VESSELS of the HEART.
The production of an image obtained by cameras that detect the radioactive emissions of an injected radionuclide as it has distributed differentially throughout tissues in the body. The image obtained from a moving detector is called a scan, while the image obtained from a stationary camera device is called a scintiphotograph.
A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.
The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.
The volume of BLOOD passing through the HEART per unit of time. It is usually expressed as liters (volume) per minute so as not to be confused with STROKE VOLUME (volume per beat).
Projection of near-IR light (INFRARED RAYS), in the 700-1000 nm region, across an object in parallel beams to an array of sensitive photodetectors. This is repeated at various angles and a mathematical reconstruction provides three dimensional MEDICAL IMAGING of tissues. Based on the relative transparency of tissues to this spectra, it has been used to monitor local oxygenation, brain and joints.
Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.
Lower lateral part of the cerebral hemisphere responsible for auditory, olfactory, and semantic processing. It is located inferior to the lateral fissure and anterior to the OCCIPITAL LOBE.
A noninflammatory, progressive occlusion of the intracranial CAROTID ARTERIES and the formation of netlike collateral arteries arising from the CIRCLE OF WILLIS. Cerebral angiogram shows the puff-of-smoke (moyamoya) collaterals at the base of the brain. It is characterized by endothelial HYPERPLASIA and FIBROSIS with thickening of arterial walls. This disease primarily affects children but can also occur in adults.
A representation, generally small in scale, to show the structure, construction, or appearance of something. (From Random House Unabridged Dictionary, 2d ed)
Unstable isotopes of nitrogen that decay or disintegrate emitting radiation. N atoms with atomic weights 12, 13, 16, 17, and 18 are radioactive nitrogen isotopes.
Computed tomography where there is continuous X-ray exposure to the patient while being transported in a spiral or helical pattern through the beam of irradiation. This provides improved three-dimensional contrast and spatial resolution compared to conventional computed tomography, where data is obtained and computed from individual sequential exposures.
A specialty field of radiology concerned with diagnostic, therapeutic, and investigative use of radioactive compounds in a pharmaceutical form.
A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.
Neoplasms of the bony part of the skull.
Methods developed to aid in the interpretation of ultrasound, radiographic images, etc., for diagnosis of disease.
A guanidine analog with specific affinity for tissues of the sympathetic nervous system and related tumors. The radiolabeled forms are used as antineoplastic agents and radioactive imaging agents. (Merck Index, 12th ed) MIBG serves as a neuron-blocking agent which has a strong affinity for, and retention in, the adrenal medulla and also inhibits ADP-ribosyltransferase.
A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.
The hemodynamic and electrophysiological action of the left HEART VENTRICLE. Its measurement is an important aspect of the clinical evaluation of patients with heart disease to determine the effects of the disease on cardiac performance.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Substances used to allow enhanced visualization of tissues.
Radionuclide ventriculography where scintigraphic data is acquired during repeated cardiac cycles at specific times in the cycle, using an electrocardiographic synchronizer or gating device. Analysis of right ventricular function is difficult with this technique; that is best evaluated by first-pass ventriculography (VENTRICULOGRAPHY, FIRST-PASS).
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Posterior portion of the CEREBRAL HEMISPHERES responsible for processing visual sensory information. It is located posterior to the parieto-occipital sulcus and extends to the preoccipital notch.
Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
A non-inherited congenital condition with vascular and neurological abnormalities. It is characterized by facial vascular nevi (PORT-WINE STAIN), and capillary angiomatosis of intracranial membranes (MENINGES; CHOROID). Neurological features include EPILEPSY; cognitive deficits; GLAUCOMA; and visual defects.
A catecholamine derivative with specificity for BETA-1 ADRENERGIC RECEPTORS. It is commonly used as a cardiotonic agent after CARDIAC SURGERY and during DOBUTAMINE STRESS ECHOCARDIOGRAPHY.
Prolonged dysfunction of the myocardium after a brief episode of severe ischemia, with gradual return of contractile activity.
The amount of BLOOD pumped out of the HEART per beat, not to be confused with cardiac output (volume/time). It is calculated as the difference between the end-diastolic volume and the end-systolic volume.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
Types of spiral computed tomography technology in which multiple slices of data are acquired simultaneously improving the resolution over single slice acquisition technology.
A graphic means for assessing the ability of a screening test to discriminate between healthy and diseased persons; may also be used in other studies, e.g., distinguishing stimuli responses as to a faint stimuli or nonstimuli.
Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
In statistics, a technique for numerically approximating the solution of a mathematical problem by studying the distribution of some random variable, often generated by a computer. The name alludes to the randomness characteristic of the games of chance played at the gambling casinos in Monte Carlo. (From Random House Unabridged Dictionary, 2d ed, 1993)
Use of radiolabeled antibodies for diagnostic imaging of neoplasms. Antitumor antibodies are labeled with diverse radionuclides including iodine-131, iodine-123, indium-111, or technetium-99m and injected into the patient. Images are obtained by a scintillation camera.
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
Involuntary, forcible, rapid, jerky movements that may be subtle or become confluent, markedly altering normal patterns of movement. Hypotonia and pendular reflexes are often associated. Conditions which feature recurrent or persistent episodes of chorea as a primary manifestation of disease are referred to as CHOREATIC DISORDERS. Chorea is also a frequent manifestation of BASAL GANGLIA DISEASES.
A gamma-emitting radionuclide imaging agent used for the diagnosis of diseases in many tissues, particularly in the gastrointestinal system, cardiovascular and cerebral circulation, brain, thyroid, and joints.
Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
Contractile activity of the MYOCARDIUM.
Surgery performed on the heart.
The diversion of RADIATION (thermal, electromagnetic, or nuclear) from its original path as a result of interactions or collisions with atoms, molecules, or larger particles in the atmosphere or other media. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.
The lower right and left chambers of the heart. The right ventricle pumps venous BLOOD into the LUNGS and the left ventricle pumps oxygenated blood into the systemic arterial circulation.
An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium.
Recording of electric currents developed in the brain by means of electrodes applied to the scalp, to the surface of the brain, or placed within the substance of the brain.
Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
The attitude and behavior associated with an individual using the computer.
The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.
Computed tomography modalities which use a cone or pyramid-shaped beam of radiation.
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
A subfamily of G-PROTEIN-COUPLED RECEPTORS that bind the neurotransmitter DOPAMINE and modulate its effects. D2-class receptor genes contain INTRONS, and the receptors inhibit ADENYLYL CYCLASES.
Striped GRAY MATTER and WHITE MATTER consisting of the NEOSTRIATUM and paleostriatum (GLOBUS PALLIDUS). It is located in front of and lateral to the THALAMUS in each cerebral hemisphere. The gray substance is made up of the CAUDATE NUCLEUS and the lentiform nucleus (the latter consisting of the GLOBUS PALLIDUS and PUTAMEN). The WHITE MATTER is the INTERNAL CAPSULE.
A tomographic technique for obtaining 3-dimensional images with transmission electron microscopy.
A relatively common neoplasm of the CENTRAL NERVOUS SYSTEM that arises from arachnoidal cells. The majority are well differentiated vascular tumors which grow slowly and have a low potential to be invasive, although malignant subtypes occur. Meningiomas have a predilection to arise from the parasagittal region, cerebral convexity, sphenoidal ridge, olfactory groove, and SPINAL CANAL. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2056-7)
Unexpected rapid natural death due to cardiovascular collapse within one hour of initial symptoms. It is usually caused by the worsening of existing heart diseases. The sudden onset of symptoms, such as CHEST PAIN and CARDIAC ARRHYTHMIAS, particularly VENTRICULAR TACHYCARDIA, can lead to the loss of consciousness and cardiac arrest followed by biological death. (from Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 7th ed., 2005)
Pathological conditions of intracranial ARTERIES supplying the CEREBRUM. These diseases often are due to abnormalities or pathological processes in the ANTERIOR CEREBRAL ARTERY; MIDDLE CEREBRAL ARTERY; and POSTERIOR CEREBRAL ARTERY.
Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.
A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
Unstable isotopes of carbon that decay or disintegrate emitting radiation. C atoms with atomic weights 10, 11, and 14-16 are radioactive carbon isotopes.
Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
Tests designed to assess neurological function associated with certain behaviors. They are used in diagnosing brain dysfunction or damage and central nervous system disorders or injury.
Self-generated faint acoustic signals from the inner ear (COCHLEA) without external stimulation. These faint signals can be recorded in the EAR CANAL and are indications of active OUTER AUDITORY HAIR CELLS. Spontaneous otoacoustic emissions are found in all classes of land vertebrates.
An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.
Treatment process involving the injection of fluid into an organ or tissue.
Positive test results in subjects who do not possess the attribute for which the test is conducted. The labeling of healthy persons as diseased when screening in the detection of disease. (Last, A Dictionary of Epidemiology, 2d ed)
The veins and arteries of the HEART.
A cognitive disorder marked by an impaired ability to comprehend or express language in its written or spoken form. This condition is caused by diseases which affect the language areas of the dominant hemisphere. Clinical features are used to classify the various subtypes of this condition. General categories include receptive, expressive, and mixed forms of aphasia.
A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.
Assessment of sensory and motor responses and reflexes that is used to determine impairment of the nervous system.
Large subcortical nuclear masses derived from the telencephalon and located in the basal regions of the cerebral hemispheres.
The formation of an area of NECROSIS in the CEREBRUM caused by an insufficiency of arterial or venous blood flow. Infarcts of the cerebrum are generally classified by hemisphere (i.e., left vs. right), lobe (e.g., frontal lobe infarction), arterial distribution (e.g., INFARCTION, ANTERIOR CEREBRAL ARTERY), and etiology (e.g., embolic infarction).
Upper central part of the cerebral hemisphere. It is located posterior to central sulcus, anterior to the OCCIPITAL LOBE, and superior to the TEMPORAL LOBES.
The amount of radiation energy that is deposited in a unit mass of material, such as tissues of plants or animal. In RADIOTHERAPY, radiation dosage is expressed in gray units (Gy). In RADIOLOGIC HEALTH, the dosage is expressed by the product of absorbed dose (Gy) and quality factor (a function of linear energy transfer), and is called radiation dose equivalent in sievert units (Sv).
A method of recording heart motion and internal structures by combining ultrasonic imaging with exercise testing (EXERCISE TEST) or pharmacologic stress.
Narrowing or constriction of a coronary artery.
Techniques for labeling a substance with a stable or radioactive isotope. It is not used for articles involving labeled substances unless the methods of labeling are substantively discussed. Tracers that may be labeled include chemical substances, cells, or microorganisms.
A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.
Various units or machines that operate in combination or in conjunction with a computer but are not physically part of it. Peripheral devices typically display computer data, store data from the computer and return the data to the computer on demand, prepare data for human use, or acquire data from a source and convert it to a form usable by a computer. (Computer Dictionary, 4th ed.)
Imaging techniques used to colocalize sites of brain functions or physiological activity with brain structures.
Freedom from activity.
The restoration of blood supply to the myocardium. (From Dorland, 28th ed)
A technetium imaging agent used in renal scintigraphy, computed tomography, lung ventilation imaging, gastrointestinal scintigraphy, and many other procedures which employ radionuclide imaging agents.
Unstable isotopes of fluorine that decay or disintegrate emitting radiation. F atoms with atomic weights 17, 18, and 20-22 are radioactive fluorine isotopes.
Tomography using x-ray transmission.
Drugs used to cause dilation of the blood vessels.
Methods of creating machines and devices.
Familiarity and comfort in using computers efficiently.
A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
The part of brain that lies behind the BRAIN STEM in the posterior base of skull (CRANIAL FOSSA, POSTERIOR). It is also known as the "little brain" with convolutions similar to those of CEREBRAL CORTEX, inner white matter, and deep cerebellar nuclei. Its function is to coordinate voluntary movements, maintain balance, and learn motor skills.
Emission or propagation of acoustic waves (SOUND), ELECTROMAGNETIC ENERGY waves (such as LIGHT; RADIO WAVES; GAMMA RAYS; or X-RAYS), or a stream of subatomic particles (such as ELECTRONS; NEUTRONS; PROTONS; or ALPHA PARTICLES).
X-ray image-detecting devices that make a focused image of body structures lying in a predetermined plane from which more complex images are computed.
A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the temporal lobe, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see EPILEPSY, COMPLEX PARTIAL) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic (i.e., related to an identified disease process or lesion). (From Adams et al., Principles of Neurology, 6th ed, p321)
A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.
Studies determining the effectiveness or value of processes, personnel, and equipment, or the material on conducting such studies. For drugs and devices, CLINICAL TRIALS AS TOPIC; DRUG EVALUATION; and DRUG EVALUATION, PRECLINICAL are available.
The thin layer of GRAY MATTER on the surface of the CEREBRAL HEMISPHERES that develops from the TELENCEPHALON and folds into gyri and sulchi. It reaches its highest development in humans and is responsible for intellectual faculties and higher mental functions.
That portion of the electromagnetic spectrum in the visible, ultraviolet, and infrared range.
Small-scale tests of methods and procedures to be used on a larger scale if the pilot study demonstrates that these methods and procedures can work.
The presence of an increased amount of blood in a body part or an organ leading to congestion or engorgement of blood vessels. Hyperemia can be due to increase of blood flow into the area (active or arterial), or due to obstruction of outflow of blood from the area (passive or venous).
Pathological conditions involving the HEART including its structural and functional abnormalities.
Techniques used for determining the values of photometric parameters of light resulting from LUMINESCENCE.
Sodium chloride-dependent neurotransmitter symporters located primarily on the PLASMA MEMBRANE of serotonergic neurons. They are different than SEROTONIN RECEPTORS, which signal cellular responses to SEROTONIN. They remove SEROTONIN from the EXTRACELLULAR SPACE by high affinity reuptake into PRESYNAPTIC TERMINALS. Regulates signal amplitude and duration at serotonergic synapses and is the site of action of the SEROTONIN UPTAKE INHIBITORS.
Organic, monobasic acids derived from hydrocarbons by the equivalent of oxidation of a methyl group to an alcohol, aldehyde, and then acid. Fatty acids are saturated and unsaturated (FATTY ACIDS, UNSATURATED). (Grant & Hackh's Chemical Dictionary, 5th ed)
Gases, fumes, vapors, and odors escaping from the cylinders of a gasoline or diesel internal-combustion engine. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed & Random House Unabridged Dictionary, 2d ed)
Systems composed of a computer or computers, peripheral equipment, such as disks, printers, and terminals, and telecommunications capabilities.
Behavioral manifestations of cerebral dominance in which there is preferential use and superior functioning of either the left or the right side, as in the preferred use of the right hand or right foot.
The largest of the cerebral arteries. It trifurcates into temporal, frontal, and parietal branches supplying blood to most of the parenchyma of these lobes in the CEREBRAL CORTEX. These are the areas involved in motor, sensory, and speech activities.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
Regulation of the rate of contraction of the heart muscles by an artificial pacemaker.
Radiography of the vascular system of the brain after injection of a contrast medium.
Compression of the heart by accumulated fluid (PERICARDIAL EFFUSION) or blood (HEMOPERICARDIUM) in the PERICARDIUM surrounding the heart. The affected cardiac functions and CARDIAC OUTPUT can range from minimal to total hemodynamic collapse.
Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.
Holmium. An element of the rare earth family of metals. It has the atomic symbol Ho, atomic number 67, and atomic weight 164.93.
Measurement of the intensity and quality of fluorescence.
Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3)
Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.
Branch of the common carotid artery which supplies the anterior part of the brain, the eye and its appendages, the forehead and nose.
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
The time frame after a meal or FOOD INTAKE.
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
Photosensitive afferent neurons located in the peripheral retina, with their density increases radially away from the FOVEA CENTRALIS. Being much more sensitive to light than the RETINAL CONE CELLS, the rod cells are responsible for twilight vision (at scotopic intensities) as well as peripheral vision, but provide no color discrimination.
One of the catecholamine NEUROTRANSMITTERS in the brain. It is derived from TYROSINE and is the precursor to NOREPINEPHRINE and EPINEPHRINE. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (RECEPTORS, DOPAMINE) mediate its action.
A nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.

Biological factors and overestimation of left ventricular ejection fraction by gated SPECT. (1/59)

BACKGROUND: Some patients present an overestimated left ventricular ejection fraction (LVEF) on electrocardiogram-gated myocardial scintigraphy (gated SPECT). OBJECTIVE: To establish the relationship between biological factors and overestimated LVEF. METHODS: We selected 3838 patients who underwent gated SPECT between May 20, 2000 and September 16, 2005 with normal perfusion images and LVEF > or =50%. The following variables were analyzed: gender (29.4% females and 70.6% males), age (from 20 to 94 years - mean: 56 years), weight (from 33.5 to 150 kg - mean: 79.6 kg), height (from 138 to 220 cm - mean: 171 cm) and BMI (from 13.9 to 54 - mean: 27.2). In a subgroup of 1002 patients who underwent echocardiogram, the diastolic diameter (from 36 to 68 mm - mean 47.5 mm) and systolic diameter (from 22 to 41 mm - mean 29.8 mm) variables were included. The patients were divided into two groups: normal LVEF (< or =80%) and overestimated LVEF (>80%). The odds ratio (OR) for presenting an overestimated LVEF was calculated for each variable using logistic regression. RESULTS: The following odds ratios were found (p < 0.005): female gender OR = 3.585 (95%CI: 2.745 to 4.683), age in years OR = 1.020 (95%CI: 1.011 to 1.029) and height in cm OR = 0.893 (95%CI: 0.829 to 0.962). Weight and BMI were not significantly associated with LVEF (p>0.2). In the subgroup of 1002 patients, a statistically significant influence was found in overestimated LVEF values for the systolic diameter, gender and height variables. CONCLUSION: Although systolic diameter influences the overestimation of LVEF, the gender and height variables have an independent influence on LVEF overestimation by gated SPECT.  (+info)

Echocardiographic and cardiac single photon emission computed tomography predictors of left ventricle reverse remodeling after surgical revascularization in patients with ischemic cardiomyopathy and left ventricle systolic dysfunction. (2/59)

BACKGROUND: The extent of scar or viable hypocontractile myocardial tissue determines postinfarction left ventricle remodeling. The aim of this pilot study was to evaluate the revascularization effect in a group of patients with ischemic cardiomyopathy and LV systolic dysfunction indicated for surgical revascularization, based on evidence for multivessel disease on coronarography and viable myocardium (CMR, SPECT). AIMS: To evaluate the revascularization effect in patients with ischemic LV systolic dysfunction and to find preoperative predictors of revascularization effect. METHODS: 33 patients (64+/-11 years) with baseline LVEF 34.9+/-9.3 % were included in the study. After a follow-up of 10.7+/-1.2 months, ECHO and SPECT were performed again. The whole group of patients was divided according to revascularization effect (postoperative increase LVEF > 5 % and postoperative decrease LVESV > 5 % compared with baseline) into revascularization responders (R, n = 22) and nonresponders (NR, n = 11). RESULTS: At baseline there was no difference between the subgroups in LVEF (R = 35.7+/-11.0 % vs. NR = 34.3+/-8.2 %), EDV (R = 183.6+/-43.2 vs. NR = 180.2+/-80.5 ml), ESV (R = 118.5+/-40.4 vs. NR = 119.7+/-55.2 ml). The responders showed in a revascularization effect subanalysis differences in the values of LVEF (+9.8+/-8.1 %, p < 0.009), reduction of EDV (-39.9+/-50.9 ml, p = 0.05) and ESV (-35.4+/-42.6 ml, p = 0,002) compared with baseline. The only preoperative parameters predicting LV reverse remodeling were the T(E-Em) (R = -10.6+/-44.1 vs. NR = 29.7+/-43.7 ms, p = 0.037) and the size of fixed perfusion defect (FPD) (R = 11.9+/-13.5 vs. NR = 22.9+/-15.3 % of LV, p = 0.044). CONCLUSIONS: Patients with ischemic LV systolic dysfunction with a preoperatively determined myocardial viability develop LV reverse remodeling. The only preoperative parameters predicting LV reverse remodeling were echocardiographic T(E-Em) and FPD on SPECT.  (+info)

Low-dose dobutamine gated-SPECT analysis of left ventricular segmental wall thickening in ischemic cardiomyopathy. (3/59)

INTRODUCTION AND OBJECTIVES: The objective of this study was to use low-dose dobutamine (LDD) gated single-photon emission computed tomography (SPECT) to evaluate segmental thickening of the left ventricle (LV) and its relationship with changes in ejection fraction (EF) and ventricular volumes in patients with ischemic cardiomyopathy. METHODS: This prospective multicenter study involved 89 patients with ischemic cardiomyopathy (i.e., EF < or =40%) who underwent LDD gated-SPECT at rest. The LV was divided into 17 segments and systolic thickening was assessed in a total of 1513 segments during LDD infusion. RESULTS; A significant increase in LVEF (33.2% vs. 30.8%; P< .001) was observed during LDD infusion and occurred at the expense of a reduction in end-systolic volume (130.5 mL vs. 136.4 mL; P=.005). The increase in EF was > or =5% in 33.7% of patients, while the EF decreased by > or =5% in 5.6% of patients. With LDD infusion, both an improvement in > or =3 segments with severely decreased baseline thickening (odds ratio [OR] = 18.3; 95% confidence interval [CI], 5.3-63) and an improvement in > or =10 segments with mild-to-moderate alterations in baseline thickening (OR = 4.53; 95% CI, 1.26-16.16) were associated with a > or =5% increase in LVEF. CONCLUSIONS: During the assessment of global left ventricular contractile reserve by LDD gated-SPECT, attention should be paid not only to the behavior of segments with severely decreased baseline thickening, which are generally regarded as indicating viability, but also to segments with mild-to-moderate alterations and to those in which thickening decreases.  (+info)

Incremental prognostic value of cardiac function assessed by ECG-gated myocardial perfusion SPECT for the prediction of future acute coronary syndrome. (4/59)

BACKGROUND: The prognostic value of ECG-gated rest 201Tl/stress 99mTc-tetrofosmin myocardial perfusion single-photon emission computed tomography for the prediction of acute coronary syndrome (ACS: myocardial infarction (MI) and unstable angina (UA)) and the implications of ejection fraction (EF) has not yet been defined in Japanese. METHODS AND RESULTS: The 1,895 patients were followed up for the occurrence ACS. The mean follow-up interval was 26.9+/-15.5 months. The 142 patients with revascularization within 60 days were censored. Summed stress score (SSS) and summed difference score (SDS) were calculated. The 19 MI and 29 UA occurred (1.1% and 1.6%, respectively). Univariate Cox analysis showed that hypertension (Wald 5.09, p<0.05), poststress EF (Wald 10.9, p<0.01), SSS (Wald 12.4, p<0.001) and SDS (Wald 18.7, p<0.001) were significant predictors of ACS. Multivariate Cox analysis showed that hypertension (Wald 4.27, p<0.05) and SDS (Wald 8.59, p<0.01) were independent predictors. When multiple clinical risk factors (number of coronary risk factors > or =2), significant ischemia (SDS > or =4) and low EF (EF <45%) were applied to multivariate Cox analysis, the combination of significant ischemia and low EF showed the highest predictive value (Wald 11.9; p<0.001) for future ACS. CONCLUSION: Poststress EF added incremental prognostic value for the prediction of ACS.  (+info)

Respiratory motion detection and correction in ECG-gated SPECT: a new approach. (5/59)


Intensive cardiovascular risk factors therapy and prevalence of silent myocardial ischaemia in patients with type 2 diabetes. (6/59)


Validation of gated blood-pool SPECT regional left ventricular function measurements. (7/59)


Single photon emission computed tomography: an alternative imaging modality in left ventricular evaluation. (8/59)

Various diagnostic imaging modalities have been used for quantitative left ventricular (LV) parameters. Because of the suboptimal value of the most widely used technology, two-dimensional (2D) echocardiography, 3D ultrasonographic imaging has improved accuracy for LV volume and function. Single photon emission computed tomography (SPECT) is another diagnostic method where LV volumetric and functional parameters can be accurately provided by gated myocardial perfusion tomographic slices. First pass radionuclide venticulography is another imaging modality which has some practical limitations. Despite lower ejection fraction (EF) values compared with invasive approach, noninvasive techniques are accurate in determination of normal and depressed EF. Noninvasive techniques with 3D approach including gated SPECT are beneficial for not only global but also regional LV evaluation. It has been mentioned that the slight difference between echocardiography and SPECT could be caused by the diverse population studied. The results of diagnostic stress tests support that SPECT is feasible to use in evaluation of LV volume and functional analysis. Magnetic resonance imaging is an expensive modality to use routinely, but it preserves its importance in selected patients for providing precise LV geometric data.  (+info)

Background: Phase analysis from gated single photon emission computed tomography myocardial perfusion imaging (GSPECT MPI) has emerged as an attractive means to assess left ventricular mechanical dyssynchrony. Whether dyssynchrony assessed by GSPECT MPI can identify patients at increased risk of mortality is unknown.. Methods: We identified all patients with angiographically significant coronary disease and a GSPECT MPI in the Duke Databank for Cardiovascular Disease between July 2003 and August 2009. The range of time during which 95% of the left ventricle is initiating contraction (phase bandwidth) and the degree of heterogeneity in the distribution of segmental initiation of mechanical contraction (phase standard deviation (SD)) by GSPECT MPI were measured. To evaluate the relationship between each measure of dyssynchrony and long-term survival, unadjusted and adjusted Cox proportional hazards models were constructed.. Results: A total of 1434 patients were identified.The median age was 64 ...
The clinical use of nuclear cardiology for the assessment of myocardial ischemia continues to grow at an unprecedented rate. Part of the reason for this growth is the technical advances in single photon emission computerized tomography (SPECT). SPECT has been shown to provide high contrast images superior to planar imaging techniques. An important and recent technical advancement in SPECT has been ECG-gated myocardial perfusion SPECT to generate simultaneous myocardial p ...
Introduction: Diastolic dyssynchrony is increasingly being recognized in both the adult and pediatric population. Increasing diastolic dyssynchrony has correlated with increased pulmonary capillary wedge pressures and worse clinical outcomes in patients with normal cardiac anatomy. No data exist in patients with single right ventricle (sRV) physiology. Goal of this study was to determine if diastolic dyssynchrony in patients with sRV physiology correlates with ventricular end-diastolic pressures (VEDP) obtained via cardiac catheterization.. Methods: Tissue Doppler imaging (TDI) and strain rate (SR) analysis of sRV patients undergoing catheterization were performed. TDI analysis was performed at the level of the atrioventricular valve. Time interval from onset of QRS to peak TDI e wave of the respective walls was obtained. Differences in intervals were calculated: QRS(RV) - QRS(IVS) and QRS(RV) - QRS(LV). The sRV was separated into a six segment model for SR analysis. Time interval from onset of ...
The first part of the webinar will provide an overview of established and exciting, new applications of radionuclide imaging in heart failure. In the second part the speaker will describe how ECG-gated Myocardial Perfusion SPECT imaging is used to measure the regional onset of mechanical contraction as an indicator of LV intraventricular dyssynchrony (LVD). The session will also address how biventricular pacemakers are being used to treat systolic heart failure in patients with advanced left bundle branch block using Cardiac Resynchronization Therapy (CRT) and the role that LVD plays in predicting CRT response and assessing treatment. The potential of this use of LVD will be discussed under the results of the IAEA funded VISION-CRT study ...
If you specify the WLLCHISQ option in the TABLES statement, PROC SURVEYFREQ computes a Wald test for independence based on the log odds ratios. For more information about Wald tests, see the section Wald Chi-Square Test. For a two-way table of R rows and C columns, the Wald log-linear test is based on the (R - 1)(C - 1)-dimensional array of elements ...
TY - JOUR. T1 - Safety of and tolerance to adenosine infusion for myocardial perfusion single-photon emission computed tomography in a Japanese population. AU - Hatanaka, Kunihiko. AU - Doi, Masayuki. AU - Hirohata, Satoshi. AU - Kamikawa, Shigeshi. AU - Kaji, Yoko. AU - Katoh, Tsutomu. AU - Kusachi, Shozo. AU - Ninomiya, Yoshifumi. AU - Ohe, Tohru. PY - 2007. Y1 - 2007. N2 - Background: Adenosine has been available for use in myocardial perfusion single-photon emission computed tomography (SPECT) in Japan since 2005. The purpose of this study was to evaluate the safety of and tolerance to thallium-201 myocardial perfusion SPECT with intravenous adenosine infusion in Japanese patients with suspected coronary artery disease. Methods and Results: Two hundred and six consecutive patients who underwent an adenosine infusion (120•g•·kg-1·min-1) SPECT at Sumitomo Besshi Hospital (Niihama, Japan) were investigated. The effects of adenosine infusion were monitored for each patient. A coronary ...
TY - JOUR. T1 - Prognostic implications of myocardial perfusion single-photon emission computed tomography in the elderly. AU - Hachamovitch, Rory. AU - Kang, Xingping. AU - Amanullah, Aman M.. AU - Abidov, Aiden. AU - Hayes, Sean W.. AU - Friedman, John D.. AU - Cohen, Ishac. AU - Thomson, Louise E.J.. AU - Germano, Guido. AU - Berman, Daniel S.. PY - 2009/12. Y1 - 2009/12. N2 - BACKGROUND- The goal of this study was to assess the clinical value of stress myocardial perfusion scintigraphy (MPS) in elderly patients (,75 years of age). METHODS AND RESULTS: We followed up 5200 elderly patients (41% exercise) after dual-isotope MPS over 2.8±1.7 years (362 cardiac deaths [CDs], 7.0%, 2.6%/y) and a subset with extended follow-up (684 patients for 6.2±2.9 years; 320 all-cause deaths). Survival modeling of CD revealed that both MPS-measured ischemia and fixed defect added incrementally to pre-MPS data in both adenosine and exercise stress patients. Modeling a subset with gated MPS (n=2472) revealed ...
Abstract in English:. INTRODUCTION Heart failure, primarily in the elderly, is a growing epidemic in todays world. It leads to high rates of disability and mortality, as well as significant health care expenditures, making it important to assess possible predictors of adverse cardiac events. In Cuba, heart failure mortality is 19.1/100,000 population. OBJECTIVES Assess the value of stress-rest protocol gated-SPECT for identifying patients with symptomatic heart failure likely to suffer adverse cardiac events. METHODS A study was conducted of 52 patients (mean age 59 years, SD 9; 62% women) with functional capacity II/III (New York Heart Association scale) and left ventricular ejection fraction ,40%. Patients were divided into two groups based on coronary heart disease diagnosis: those with coronary heart disease (41), labeled ischemic; and those without (11), labeled nonischemic. All underwent gated SPECT myocardial perfusion scintigraphy with technetium-99m-labeled methoxyisobutyl isonitrile, ...
Lowering the administered dose in SPECT myocardial perfusion imaging (MPI) has become an important clinical problem. In this study we investigate the potential benefit of applying a deep learning (DL) approach for suppressing the elevated imaging noise in low-dose SPECT-MPI studies. We adopt a supervised learning approach to train a neural network by using image pairs obtained from full-dose (target) and low-dose (input) acquisitions of the same patients. In the experiments, we made use of acquisitions from 1,052 subjects and demonstrated the approach for two commonly used reconstruction methods in clinical SPECT-MPI: 1) filtered backprojection (FBP), and 2) ordered-subsets expectation-maximization (OSEM) with corrections for attenuation, scatter and resolution. We evaluated the DL output for the clinical task of perfusion-defect detection at a number of successively reduced dose levels (1/2, 1/4, 1/8, 1/16 of full dose). The results indicate that the proposed DL approach can achieve substantial noise
SPECT myocardial perfusion imaging (MPI) is the most validated non-invasive method to test for ischemia, and this procedure is performed over 15 to
肺移植後患者に対する肺換気/血流 SPECT/CT を用いた閉塞性細気管支炎症候群の診断的価値に関する検 ...
I was diagnosed with a small heart mummur 11 years ago when I was pregnant with my son. Doctors told me it was small and it was nonthing to worry about. My mother and her side of her family have Cong...
Bad Homburg v.d. Höhe, 31. August 2020 - Für den Neubau des „Hauses im Wald in Schmitten hat die Else Kröner-Fresenius-Stiftung (EKFS) einen neuen architektonischen Entwurf entwickelt und das Nutzungskonzepts modifiziert. ...
TY - JOUR. T1 - Are shades of gray prognostically useful in reporting myocardial perfusion single-photon emission computed tomography?. AU - Abidov, Aiden. AU - Hachamovitch, Rory. AU - Hayes, Sean W.. AU - Friedman, John D.. AU - Cohen, Ishac. AU - Kang, Xingping. AU - Yang, Ling De. AU - Thomson, Louise. AU - Germano, Guido. AU - Slomka, Piotr. AU - Berman, Daniel S.. N1 - Copyright: Copyright 2010 Elsevier B.V., All rights reserved.. PY - 2009/7. Y1 - 2009/7. N2 - We have advocated the use of a 5-category normal, probably normal, equivocal, probably abnormal, and definitely abnormal approach to final interpretation of myocardial perfusion single-photon emission computed tomography (SPECT). The prognostic value of expressing levels of certainty compared with a dichotomous normal/abnormal classification or categories for summed stress scores is unclear. Methods and Results-Myocardial perfusion SPECT (MPS) was visually assessed using a standard semiquantitative approach, yielding ...
46 patients with a large anterior myocardial infarction (peak CK 2399-11213U/L, peak Tn I 68-249 ng/dL) were included in the study 6-9 days after primary PCI. The control group involved 12 patients not subjected to cell therapy (1:4 assignment). To evaluate myocardial perfusion and viability, regional and global left ventricular contractility, GSPECT was performed 2 days prior to autologous CD34+ cells transcoronary application. In addition, in a subgroup of 23 consecutive patients the cells were labeled with 99mTc-HMPAO to assess their early myocardial retention (i.e., homing to the infarct zone vs. border zone vs. non-infarcted area, myocardial SPECT) and proportion of retention in the heart vs. other organs (whole body SPECT). After 6 months, GSPECT was repeated ...
Myocardial Perfusion Imaging is used to diagnose, and estimate the prognosis of patients with coronary artery disease. Increased attention around the use radiation in medical imaging coupled with new software allows the opportunity to try and reduce the radiation perfusion imaging by half. Software advances allow us to process images that have less radiation counts in the heart without losing the ability to determine the degree of heart disease. Patients underwent a usual dose and low dose stress myocardial perfusion technetium 99m study at the Ottawa Heart Institute. There were no significant differences between the images. The image quality and the parameters used determine significant heart disease were similar. We became an early adopter of the low dose studies and now routinely perform this on our patients. We also followed the first cohort of patients for 12 months to ensure that we saw no problems with doing a low dose test in the long term. Although we did not collect data on all of the ...
Myocardial perfusion imaging (MPI) is a commonly used diagnostic modality for risk stratification in patients with known or suspected coronary artery
In this study, we aimed to explore the possibility of evaluating the attitudes of subjects as to whether they liked or disliked visually presented pictures. We measured magnetoencephalgraphic (MEG) responses and conducted a phase analysis of the specific alpha band frequency component. We gave ten subjects a questionnaire with images of animals prepared beforehand. We selected 30 pictures, from which 15 pictures were used as positive impression images (Good Images) and 15 pictures as negative impression images (Bad Images). The MEG responses were measured with a 122-channel magnetometer system. We obtained the power spectrum of MEG responses and carried out a phase analysis of the peak frequency of the alpha band. As a result, significant phase synchronicity was confirmed for the negative impression images.. ...
Hypertension is one of the most important risk factors for cardiovascular disease. However, hypertension may also result in left ventricular dyssynchrony (LVD) which is characterized by delayed activation of certain ventricular segments leading to un
Cute lil hearts. Also shown - Big Hearts, Medium Hearts. Vannas Choice yarn and Freshstitches Design. Purchase of a heart supports Jump Rope For Heart and Hoops For Heart.
Okay, I admit it. I posted this entire release just so I could wonder aloud about the use of office as a verb. Is that common practice and I just missed it? Ill admit I was caught behind the times with effort as a verb. I heard some guy on sports talk radio this morning utter the sentence were efforting Stephen A. Smith right now, meaning that theyre trying to get the loud mouth basketball commenter who just got canned (or maybe not retained) by ESPN on the phone. When the sports guys have bought into the new use of the word, Im just a curmudgeon for disliking it, I suppose. I dont want to be all Andy Rooney here, but does the English language not have enough words? Weve got way more than anyone else, so I dont see why weve got to make up new ways to use words weve already got. Plus, its not like its more Twitterifically efficient or anything: He offices out of=17 characters; He is based at=14 characters. Maybe he didnt want to be based (because it sounded too base). ...
Small heart syndrome is associated with a small heart shadow on a chest X-ray or magnetic resonance imaging. It was first proposed in 1944 as neurocirculatory asthenia. Current studies show that small heart syndrome is associated with a smaller left ventricular chamber size and diminished cardiac stroke volume.[1] Small heart syndrome is characterized with weakness or fatigue even after ordinary exertion, heart palpitation, dyspnea, and fainting. Miwa and Fujita have shown that it is significantly more prevalent in ME/CFS patient (61%) compared to a control group (24%).[2] ...
TY - JOUR. T1 - Quantification of Individual Sensitivities to Ethanol in Selective Breeding Experiments. T2 - Difference Scores Versus Regression Residuals. AU - Crabbe, John C.. AU - Weigel, Ronald M.. PY - 1987/12. Y1 - 1987/12. N2 - Nagoshi et al. (Alcohol Clin Exp Res 10:343-349, 1986) have argued recently that the use of postdrug minus predrug difference scores to assess individual variability in sensitivity or tolerance to ethanol is not to be recommended. Unreliability of variables can result in biased estimates of response to treatment. Instead of difference scores, they recommend using residual scores from the regression of posttreatment on pretreatment measures. We were interested in the consequences of employing difference scores versus regression residuals for a related, but different purpose: the choice of individual animals to be mated for a selective breeding study. The availability of data from such a selective breeding experiment ongoing in the laboratory of one of us (JCC) ...
Fingerprint Dive into the research topics of Segmentation of the left ventricle in myocardial perfusion SPECT using variational level set formulation. Together they form a unique fingerprint. ...
Read Robust and automatic diagnosis of the intraventricular mechanical dyssynchrony for the left ventricle in cardiac magnetic resonance images, International Journal of Computer Assisted Radiology and Surgery on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
Since the purpose of the round robin is to assess the methods of quantification, and not identification, the identity of each of the component phases will be supplied. For those participants using Rietveld based methods for the analysis, full structural information for each of the phases will also be supplied. Participants will be asked to return the results using standard reporting forms. This should minimize the number of errors likely to occur during transcription of the data. In addition, it is requested that the diffraction data be returned to the CPD as an ASCII format file for re-analysis with a standard Rietveld code.. ...
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Patients with chest pain who underwent SPECT myocardial perfusion imaging (MPI) with an ultralow-radiation-dose gamma camera had no major cardiac events a year later. The research, published in the April issue of the Journal of Nuclear Medicine, indicates that MPI radiation dose can be slashed without adverse clinical impact.
DENVER -- The use of regadenoson (Lexiscan) is safe and can lead to cost and time efficiencies in patients undergoing exercise SPECT myocardial perfusion imaging.
CT angiography and SPECT myocardial perfusion imaging improves with the use of synchronized multimodal heart visualization software.
Hello, I am trying to understand some results I got (see below) and any assistance will be greatly appreciated. I have run a number of conditional logit models (with cluster-adjusted robust SEs) and usually, if you get a greater Wald chi-square value, you also get a greater pseudo r-square. But the models below are strange in that the first one has a great pseudo r-square value while the second one has a greater Wald chi-square value. The only thing that changes from one model to the next are the third and fourth variables starting from the bottom (i.e., in the second model, a_lneuclkm and m_lneuclkm have been substituted by a_lneuclmins and m_lneuclmins). Does anyone have any information about how the Wald test statistic is calculated so that I can relate this to how the log-likelihood and the pseudo r-square are calculated (and work out why they might be behaving in this way)? Thanks very much, Lucia. Model 1 . clogit choice commerc100 nostations popdens unemp10 imdincome imdhealth ...
Very scary indeed! Ive had 2 similar situation where Ive either gone to the ER or to my doctor (when it wasnt that bad, but I knew I needed it checked) and the bad time was inflammation around my heart and the 2nd time was, what my doctor thinks, an allergic reaction to my ex-husbands cats (we were married at the time) - inflammation but not quite the same or bad as the first time it happened. But, yeah, EKGs, check Xrays, the whole bit and then super duper ibuprofen!! I havent had any other recurrences in a number of years, but it is very very scary (the first time, I even had my left arm going number in addition to the chest pain and shortness of breath!!). Hope he feels better very soon!!. ReplyDelete ...
2006 erschien von Wald Geist Winter die erste Demo Siegreich ist das Eis, welche damals gut gefiel. Ende Dezember ist nun mit Teufelskreise das Debütalbum erschienen. Wald Geist Winter hat sich natürlich weiterentwickelt und anno 2010/2011 klingt man nicht mehr ganz so rau wie noch auf der ersten Demo. Grimmig ist der Black Metal des Duos aber nach wie vor. Einen Einklang hat man sich gespart und so legt man mit Heimkehr auch gleich direkt … mehr. ...
Der Klimawandel wird den Schweizer Wald drastisch verändern, mit Folgen für den Menschen. Die WSL erforscht die relevanten Prozesse.
Introduction: Asymptomatic diabetic patients are at increased risk of cardiovascular complications. Myocardial perfusion scan may be effective in risk evaluation in this population. Methods: 106 asymptomatic diabetic patients (age: min: 37, max: 82, mean: 57.73±8.88), including 56 females (52.8%) and 50 males (47.2%) were enrolled in the study. Myocardial perfusion scintigraphy was performed by Gated Single Photon Emission Computed Tomography (Gated-SPECT) method. Perfusion and function status was evaluated by qualitative and semi-quantitative parameters. Results: By visual analysis totally 40 out of 106 patients (37.7%) showed abnormal scan. From which, 26(24.5%) showed involvement in one, 13(12.3%) in two, and 1(0.9%) in all three vessel territories. By semi-quantitative method, from 103 patients, 28 (27.2%) were abnormal and 75 (72.8%) were normal. From all the asymptomatic diabetic patients, 11 patients (10.4%) had dilated left ventricles. Transient Ischemic Dilation (TID) was noted in 10
PURPOSE: To determine whether the assessment of regional wall thickening (WT) in addition to myocardial perfusion from stress supine acquisitions could compensate for the lack of prone acquisition and the corresponding decrease in the diagnostic performance of SPECT myocardial perfusion imaging (MPI) in patients with known or suspected coronary artery disease (CAD). METHODS: The study group comprised 41 patients (123 vessels) with known or suspected CAD prospectively recruited for systematic prone and supine 201Tl stress SPECT MPI. The diagnostic performance of SPECT MPI was determined for various image sets including nongated supine images (supine NG), nongated combined prone and supine images (prone and supine NG) and gated supine images, allowing WT evaluation from NG images in addition to perfusion (supine NG + WT) using invasive coronary angiography and fractional flow reserve as the gold standards. RESULTS: The rate of false positives was significantly higher among the supine NG images
This work involves the detection and monitoring of solvent interactions with heavy oil and bitumen. Two nondestructive methodslow-field nuclear magnetic resonance (NMR) and X-ray computer-assisted tomography (CAT)were used. It is shown that low-field NMR can be a very useful tool in understanding the relationship of viscosity, density, and asphaltene precipitation in bitumen−solvent mixtures. Such mixtures are present in solvent-related heavy oil and bitumen recovery processes, such as vapor extraction (VAPEX). As a solvent comes into contact with a heavy oil or bitumen sample, the mobility of hydrogen-bearing molecules of both solvent and oil changes. These changes are detectable through changes in the NMR relaxation characteristics of both the solvent and the oil and can be correlated to mass flux and concentration changes. Based on Ficks second law, diffusion coefficients were calculated for combinations of three oils and six solvents. X-ray CAT scanning was also used in parallel for ...
Order this Sterling Silver Cubic Zirconia Small Heart Pendant online. Free UK delivery when you spend £49 or more. Buy now at H.Samuel. Quality at affordable prices.
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Heart forms and opals..how can you go wrong. Opals have lots of colors within the stone and will go with her whole wardrobe!1 x 1 sterling heart pendant with an opal triplet and a 22k gold dot.It can be on either a 18 or 20 sterling chain.
This is a Cue bid from South. First it confirms an interest in Slam - so Souths clubs must contain no wasted values, and thus (a) there is no more than one loser in clubs and (b) there can only be 30 other HCP that count. Second it is telling North about his Ace in diamonds. North, adding his 15 HCP points will know that the partnership has 27+ out of the remaining 30 HCPs in the other suits. Sounds as if there is every chance of making all the other tricks, unless theres a missing King in the wrong place. 50:50% chance of small Heart Slam, all hanging on a finesse ...
MEDIDENT BAVARIA® steht für modernste Biologische Medizin und Zahnheilkunde, gepaart mit Entspannung und Regeneration im Bayerischen Wald!
OBJECTIVES: Septal perfusion abnormalities are frequently observed in patients with left bundle branch block (LBBB). The aim of this study was to compare myocardial perfusion imaging obtained from ungated and diastolic thallium gated single-photon emission computed tomography (SPECT) images in patients with LBBB. METHODS: Stress/rest SPECT was performed in 70 patients with LBBB [38 with coronary artery disease (CAD) (G1), 32 without (G2)] and 19 control participants (G3). Diastolic images were obtained as the sum of four diastolic bins. Perfusion was assessed by summed stress, rest, and difference scores for both diastolic and ungated images. RESULTS: In G1, there was no difference between diastolic and ungated perfusion scores. In G2, summed stress score and summed rest score were increased in diastolic versus ungated imaging, and perfusion defect extent was increased on diastolic versus ungated images at stress (diastole: 6.2 +/- 9.9% vs. ungated: 5.1 +/- 9.70/%, P = 0.01) and rest (diastole: 4.3 +/-
OBJECTIVES The value of gated single-photon emission computed tomography technetium-99m methoxyisobutylisonitrile (gated SPECT (99m)Tc-MIBI) in children is not yet established probably because gated SPECT (99m)Tc-MIBI has rarely been used in pediatric clinical and research studies. The purpose of this study was to evaluate perfusion abnormalities and left ventricular (LV) function by gated SPECT (99m)Tc-MIBI in children and adolescents with severe congenital heart disease (CHD). METHODS Seventeen children and adolescents with severe CHD (11 boys and six girls, mean age 11+/-4 years) underwent 2-day rest-stress (11 boys) or 1-day rest (six girls) gated SPECT (99m)Tc-MIBI. Myocardial perfusion was evaluated by a 17-segment model with a 5-point score to derive the summed stress score, the summed rest score (SRS), and the summed difference score based on the 4D-MSPECT software results. The extent of myocardial perfusion abnormalities was also expressed as a percentage of the LV size. The 4D-MSPECT
Objectives: Soft tissue attenuation artifacts are the most common cause of false-positives in myocardial perfusion SPECT (MPS). Few studies assessing the value
TY - JOUR. T1 - Gated myocardial perfusion SPECT [1]. AU - Currie, Geoffrey M.. AU - Wheat, Janelle M.. PY - 2005. Y1 - 2005. UR - http://www.scopus.com/inward/record.url?scp=33644889693&partnerID=8YFLogxK. M3 - Letter. C2 - 16397974. AN - SCOPUS:33644889693. VL - 33. SP - 243. JO - Journal of Nuclear Medicine Technology. JF - Journal of Nuclear Medicine Technology. SN - 0091-4916. IS - 4. ER - ...
The NM Emory Cardiac Toolbox (ECTb) v4.1 provides advanced tools for cardiac SPECT and PET analysis including comparison of perfusion to viability data, display of 3D images with coronary overlays and gated 3D cine, normal limits for agent match/mismatch as well as optional phase analysis for wall motion and evaluation of thickening. ...
Structural Characterization: Use of Transmission Electron Microscopy (TEM) in high resolution, energy filtered, conventional and convergent beam modes to characterize nitride nanostructures (quantum wells and dots). Quantitative analysis of HRTEM images using the geometric phase analysis, a projection method and images simulations ...
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May had a small heart attack just weeks after being hospitalized with a gardening injury and then being diagnosed with a compressed sciatic nerve. | iHeartRadio
Aging Backwards is a term coined by Dr. Michael Wald, The Blood Detective, to describe how each of us has the biological potential to actually reverse-age. Dr. Wald gives specific nutritional strategies that have been demonstrated in scientific studies to affect our fundamental aging process. Dr. Wald can be reached by calling 914-552-1442. www.IntegratedNutritionNY.com/email: [email protected] view more ...
... positron-emission tomography MeSH E01.370.350.350.800.800 - tomography, emission-computed, single-photon MeSH E01.370.350.350. ... computer-assisted MeSH E01.370.350.350.800 - tomography, emission-computed MeSH E01.370.350.350.800.700 - ... gated blood-pool imaging MeSH E01.370.350.710.715.710.950 - ventriculography, first-pass MeSH E01.370.350.710.800 - tomography ... cardiac MeSH E01.370.370.380.250 - exercise test MeSH E01.370.370.380.400 - heart auscultation MeSH E01.370.370.380.400.500 - ...
"EM reconstruction algorithm for emission and transmission tomography". Journal of Computer Assisted Tomography. 8 (2): 306-316 ... Geman, Stuart; McClure, Donald E. (1985). "Bayesian image analysis: An application to single photon emission tomography" (PDF ... Applying a Level Set Method for Resolving Physiologic Motions in Free-Breathing and Non-gated Cardiac MRI. FIMH, 2013, " ... Tomographic reconstruction Positron Emission Tomography Tomogram Computed Tomography Magnetic Resonance Imaging Inverse problem ...
In photon therapy, most of the radiation effect is through free radicals. Cells have mechanisms for repairing single-strand DNA ... in the 1970s and positron emission tomography (PET) in the 1980s, has moved radiation therapy from 3-D conformal to intensity- ... Taylor CW, Nisbet A, McGale P, Darby SC (December 2007). "Cardiac exposures in breast cancer radiotherapy: 1950s-1990s". ... Computer-controlled x-ray accelerators distribute precise radiation doses to malignant tumors or specific areas within the ...
... using phase analysis of gated single photon emission co ... Cardiac-Gated Single-Photon Emission Computer-Assisted ... using phase analysis of gated single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI).. METHODS: ... Phase analysis of gated SPECT MPI was used to assess LV dyssynchrony pre- and post-RFA.. RESULTS: Among the 45 patients, 3 had ... Electrophysiologic Techniques, Cardiac / methods. Female. Humans. Male. Middle Aged. Myocardial Perfusion Imaging / methods. ...
Single Photon Emission Computed Tomography (SPECT) Myocardial Perfusion Imaging Guidelines: Instrumentation, Acquisition, ... Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography * Coronary Circulation * Humans * Image Interpretation, ... Single Photon Emission Computed Tomography (SPECT) Myocardial Perfusion Imaging Guidelines: Instrumentation, Acquisition, ... Tomography, Emission-Computed, Single-Photon* / instrumentation * Tomography, Emission-Computed, Single-Photon* / methods ...
Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography * Swine * Thorax * Myocardial Reperfusion ... Each animal underwent four modes of gamma camera imaging: a cardiac and respiratory gated SPECT study, an ungated SPECT study, ... Each animal underwent four modes of gamma camera imaging: a cardiac and respiratory gated SPECT study, an ungated SPECT study, ... Each animal underwent four modes of gamma camera imaging: a cardiac and respiratory gated SPECT study, an ungated SPECT study, ...
Positron-Emission Tomography Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography Electrocardiography ...
In the experiments the authors use Monte Carlo simulated cardiac gated SPECT imaging based on the 4D NURBS-based cardiac-torso ... In low-count gated studies, it can have even greater impact than other degrading factors. Both attenuation and scatter ... In gated cardiac single photon emission computed tomography (SPECT), image reconstruction is often hampered by various ... Artifacts; Cardiac-Gated Single-Photon Emission Computer-Assisted; Tomography; Female; Humans; Image Enhancement; Image ...
Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography * Detectors * Compensation and Redress ... Block-iterative techniques for fast 4D reconstruction using a priori motion models in gated cardiac SPECT. Lalush, D. S. & Tsui ... An investigation of the estimation of ejection fractions and cardiac volumes by a quantitative gated SPECT software package in ... Combination of MCNP and SimSET for Monte Carlo simulation of SPECT with medium and high energy photons. Du, Y., Frey, E. C., ...
Cardiac Surgeons and Experts from USA, Australia, Europe, Asia, Middle East at Cardiology Conference, Interventional Cardiology ... events, Heart Disease Meetings, Cardiac Nursing Congress during 2017, 2018 ... Track 7-11Cardiac-gated single photon emission computer assisted tomography. *Track 7-12Gated blood-pool imaging ... Track 3:Cardiac Surgery Cardiac (heart) surgery is surgery on the heart or great vessels performed by cardiac surgeons. ...
Cardiac Surgeons and Experts from USA, Australia, Europe, Asia, Middle East at Cardiology Conference, Interventional Cardiology ... events, Heart Disease Meetings, Cardiac Nursing Congress during 2017, 2018 ... Cardiac-gated imaging techniques. *Gated blood-pool imaging. *Cardiac-gated single photon emission computer assisted tomography ... Cardiac Regeneration - Clinical Cardiology Congress 2018 (Hong Kong). *Cardiac Regeneration & Remodeling - Cardiac Nursing 2018 ...
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Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography/methods , Cardiac Resynchronization Therapy/methods , Cardiac ... mh:Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography (21) Order by. Year (decreasing). Relevance. Year ( ... Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography/methods , Coronary Artery Disease/complications , Diastole , ... Aged , Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography/methods , Coronary Artery Disease/diagnostic imaging ...
Female , Humans , Male , Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography , Coronary Artery Disease , ... Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography / Myocardial Perfusion Imaging / Heart Limits: Female / ... Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography / Myocardial Perfusion Imaging / Heart Limits: Female / ... Gated-SPECT revealed that, out of the patients, 64 (92.8 percent) showed images of perfusion abnormalities and 4 (7.2 percent) ...
Cardiac-Gated Imaging Techniques. *Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography ... Reconstruction of dynamic gated cardiac SPECT. Med Phys. 2006 Nov; 33(11):4384-94. ... "Gated Blood-Pool Imaging" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... This graph shows the total number of publications written about "Gated Blood-Pool Imaging" by people in this website by year, ...
Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography, Chi-Square Distribution, Coronary Circulation, Exercise ... Cardiac Remodelling, Exercise Training, Gated Single-Photon Emission Computed Tomography, Myocardial Perfusion, Oxygen ... Direct comparison between post-stress left ventricular ejection fraction by gated single-photon emission computed tomography ... evaluated by gated single-photon emission computed tomography (SPECT) imaging. Design: Randomized controlled study. Methods: ...
The periodic OFE method is used to exploit the inherent periodic nature in cardiac gated images. In this method, the optical ... known cardiac motion derived from the NURBS-based cardiac-torso (NCAT) phantom. ... we investigate the effect of different optical flow estimation methods for motion-compensated temporal processing in gated ... Motion-compensated temporal processing can have a major impact on improving the image quality in gated cardiac single photon ...
Cardiac-Gated Imaging Techniques. *Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography ... "Gated Blood-Pool Imaging" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... This graph shows the total number of publications written about "Gated Blood-Pool Imaging" by people in this website by year, ... Radionuclide ventriculography where scintigraphic data is acquired during repeated cardiac cycles at specific times in the ...
Cardiac-Gated Imaging Techniques. *Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography ... "Cardiac-Gated Imaging Techniques" by people in this website by year, and whether "Cardiac-Gated Imaging Techniques" was a major ... "Cardiac-Gated Imaging Techniques" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH ( ... Metric optimized gating for fetal cardiac MRI. Magn Reson Med. 2010 Nov; 64(5):1304-14. ...
Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography. Tomografia Computadorizada por Emissão de Fóton Único de ... Cardiac-Gated Imaging Techniques. Técnicas de Imagem de Sincronização Cardíaca. Técnicas de Imagen Sincronizada Cardíacas. ... Electron Microscope Tomography. Tomografia com Microscopia Eletrônica. Tomografía con Microscopio Electrónico. Gene Knock-In ... Electron Microscope Tomography. Tomografia com Microscopia Eletrônica. Tomografía con Microscopio Electrónico. Metabolic ...
Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography , Myocardial Perfusion Imaging , Heart failure , Tomography ... Tomography, Emission-Computed, Single-Photon - methods , Humans , Female , Male , Cardiac Pacing, Artificial - methods , Heart ... POSITRON-EMISSION-TOMOGRAPHY , LIGHT-CHAIN AMYLOIDOSIS , LOAD , CARDIOVASCULAR MAGNETIC-RESONANCE , HEART-FAILURE , ... CARDIAC & CARDIOVASCULAR SYSTEMS , NARROW QRS , HEART-FAILURE , SCAR , CARDIAC-RESYNCHRONIZATION THERAPY , DILATED ...
Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography , Myocardial Perfusion Imaging , Care and treatment , ... single photon emission computed tomography (11) 11 Filter by. Remove filter. single-photon emission computed tomography (11) 11 ... Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography - methods , Myocardial Ischemia - complications , Sensitivity ... EMISSION COMPUTED-TOMOGRAPHY , Tomography, Emission-Computed, Single-Photon - methods , Prognosis , Diabetes Complications - ...
... is a condition characterized by ischemic injury and necrosis of the cardiac muscle. Ischemic injury occurs when the blood ... Abbott BG, Abdel-Aziz I, Nagula S. Selective use of single-photon emission computed tomography myocardial perfusion imaging in ... The Rule Out Myocardial Infarction Using Computer Assisted Tomography (ROMICAT) Study. Circ Cardiovasc Qual Outcomes. 2013 Sep ... Prognostic value of stress-gated Tc-99m sestamibi SPECT after acutemyocardial infarction. Am J Cardiol. 2001 Feb 15. 87(4):381- ...
Humans , Male , Female , Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography , Myocardial Perfusion Imaging , ... Gated myocardial perfusion SPECT in patients with left bundle block but having low probability of coronary artery disease; as ... Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography (1) Myocardial Perfusion Imaging (1) ... on perfusion and functional parameters in dipyridamole Tc99m-MIBI gated myocardial perfusion SPECT which may be helpful in ...
F18-fluorodeoxglucose single-photon emission computed tomography predicts functional outcome of dyssynergic myocardium after ... Journal of Computer Assisted Tomography. 19, 1, p. 56-62 7 p.. Research output: Contribution to journal › Article › Academic › ... van Rossum, A. C., Galjee, M. A., Doesburg, T., Hofman, M. & Valk, J., 1 Mar 1993, In : The International Journal of Cardiac ... Mri of coronary arteries: 2d breath-hold vs 3d respiratory-gated acquisition. Hofman, M. B. M., Paschal, C. B., Li, D., Haacke ...
... dose computed tomography for attenuation correction of cadmium-zinc-telluride single photon emission computed tomography ... Impact on Image Quality in Ultralow-Dose Coronary Computed Tomography Angiography. Journal of Computer Assisted Tomography, 40( ... Fused cardiac hybrid imaging with coronary computed tomography angiography and positron emission tomography in patients with ... Gated SPECT myocardial perfusion imaging with cadmium-zinc-telluride detectors allows real-time assessment of dobutamine-stress ...
... positron-emission tomography MeSH E01.370.350.350.800.800 - tomography, emission-computed, single-photon MeSH E01.370.350.350. ... computer-assisted MeSH E01.370.350.350.800 - tomography, emission-computed MeSH E01.370.350.350.800.700 - ... gated blood-pool imaging MeSH E01.370.350.710.715.710.950 - ventriculography, first-pass MeSH E01.370.350.710.800 - tomography ... cardiac MeSH E01.370.370.380.250 - exercise test MeSH E01.370.370.380.400 - heart auscultation MeSH E01.370.370.380.400.500 - ...
"EM reconstruction algorithm for emission and transmission tomography". Journal of Computer Assisted Tomography. 8 (2): 306-316 ... Geman, Stuart; McClure, Donald E. (1985). "Bayesian image analysis: An application to single photon emission tomography" (PDF ... Applying a Level Set Method for Resolving Physiologic Motions in Free-Breathing and Non-gated Cardiac MRI. FIMH, 2013, " ... Tomographic reconstruction Positron Emission Tomography Tomogram Computed Tomography Magnetic Resonance Imaging Inverse problem ...
  • LV dyssynchrony as assessed by phase analysis of gated SPECT myocardial perfusion imaging in patients with Wolff-Parkinson-White syndrome. (biomedsearch.com)
  • PURPOSE: The purpose of this study was to evaluate left ventricular (LV) mechanical dyssynchrony in patients with Wolff-Parkinson-White (WPW) syndrome pre- and post-radiofrequency catheter ablation (RFA) using phase analysis of gated single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI). (biomedsearch.com)
  • METHODS: Forty-five WPW patients were enrolled and had gated SPECT MPI pre- and 2-3 days post-RFA. (biomedsearch.com)
  • Phase analysis of gated SPECT MPI was used to assess LV dyssynchrony pre- and post-RFA. (biomedsearch.com)
  • RESULTS: Among the 45 patients, 3 had gating errors, and thus 42 had SPECT phase analysis. (biomedsearch.com)
  • CONCLUSION: Phase analysis of gated SPECT MPI demonstrated that LV mechanical dyssynchrony can be present in patients with WPW syndrome. (biomedsearch.com)
  • This study supports further investigation in the relationship between electrical and mechanical activation using EPS and phase analysis of gated SPECT MPI. (biomedsearch.com)
  • Each animal underwent four modes of gamma camera imaging: a cardiac and respiratory gated SPECT study, an ungated SPECT study, a post-mortem SPECT study and an ex-situ study where the heart was sliced into five short axis slices and directly imaged. (elsevier.com)
  • Conclusions: The assessment of risk area acutely by SPECT Tc-99m sestamibi imaging is unaffected by cardiac motion obviating the necessity for gated imaging. (elsevier.com)
  • PURPOSE: In gated cardiac single photon emission computed tomography (SPECT), image reconstruction is often hampered by various degrading factors including depth-dependent spatial blurring, attenuation, scatter, motion blurring, and low data counts. (umassmed.edu)
  • In the experiments the authors use Monte Carlo simulated cardiac gated SPECT imaging based on the 4D NURBS-based cardiac-torso (NCAT) phantom with different patient geometry and lesion settings, in which the simulated ground truth is known for the purpose of quantitative evaluation. (umassmed.edu)
  • CONCLUSIONS: Correction for degrading factors such as resolution, attenuation, scatter, and motion blur can all lead to improved image quality in cardiac gated SPECT reconstruction. (umassmed.edu)
  • Objectives: To assess electromechanical dyssynchrony in CRT with LV lead implantation guided by GATED SPECT. (bvsalud.org)
  • Methods: This study included 15 patients with functional class II-IV HF and clinically optimized, ejection fraction of 35%, sinus rhythm, left bundle-branch block, and QRS ≥ 120 ms. The patients underwent electrocardiography, answered the Minnesota Living with Heart Failure Questionnaire (MLHFQ), and underwent gated myocardial perfusion SPECT up to 4 weeks before CRT, being reassessed 6 months later. (bvsalud.org)
  • Objetivos: Avaliar o dissincronismo eletromecânico na TRC com o implante do eletrodo do VE orientado por GATED SPECT. (bvsalud.org)
  • Métodos: Incluídos 15 pacientes com IC classe funcional II-IV, otimizados clinicamente, com fração de ejeção de 35%, ritmo sinusal, bloqueio de ramo esquerdo, QRS ≥ 120 ms. Realizaram eletrocardiograma, Questionário Minnesota Vivendo com Insuficiência Cardíaca (MLHFQ) e cintilografia GATED SPECT até 4 semanas antes do implante. (bvsalud.org)
  • Avaliar o valor da CPM com gated- SPECT na identificação de isquemia induzida por estresse farmacológico em pacientes com diagnóstico de doença coronária obstrutiva multiarterial. (bvsalud.org)
  • Dos pacientes , 64 (92,8 por cento) apresentaram alteração nas imagens de perfusão e 4 (7,2 por cento) apresentaram perfusão normal, sendo que, destes, três apresentaram alterações funcionais na análise do gated- SPECT . (bvsalud.org)
  • Assess the value of MPRI with gated- SPECT for tracing pharmacological stress-induced ischemia in patients with multivessel obstructive coronary disease . (bvsalud.org)
  • Gated- SPECT revealed that, out of the patients , 64 (92.8 percent) showed images of perfusion abnormalities and 4 (7.2 percent) showed normal perfusion , given that three of the latter showed functional changes. (bvsalud.org)
  • PURPOSE: Motion-compensated temporal processing can have a major impact on improving the image quality in gated cardiac single photon emission computed tomography (SPECT). (umassmed.edu)
  • In this work, we investigate the effect of different optical flow estimation methods for motion-compensated temporal processing in gated SPECT. (umassmed.edu)
  • and King, Michael A., "A quantitative study of motion estimation methods on 4D cardiac gated SPECT reconstruction" (2012). (umassmed.edu)
  • We aimed to investigate of effect of left bundle branch block [LBBB] on perfusion and functional parameters in dipyridamole Tc99m-MIBI gated myocardial perfusion SPECT which may be helpful in interpretation of myocardial perfusion imaging. (bvsalud.org)
  • Gated SPECT myocardial perfusion imaging with cadmium-zinc-telluride detectors allows real-time assessment of dobutamine-stress-induced wall motion abnormalities. (uzh.ch)
  • AIMS: To determine if perfusion stress echocardiography (PSE) with Imagify (perflubutane polymer microspheres) is comparable to stress perfusion imaging using (99m)Tc single photon emission computed tomography (SPECT) for coronary artery disease (CAD) detection. (edu.au)
  • METHODS AND RESULTS: Chronic, stable, chest pain patients (n=662) underwent Imagify PSE and gated SPECT imaging at rest and during dipyridamole stress. (edu.au)
  • Absolute Myocardial Blood Flow and Flow Reserve Assessed by Gated SPECT with Cadmium-Zinc-Telluride Detectors Using 99mTc-Tetrofosmin: Head to Head Comparison with 13N-Ammonia PET. (uzh.ch)
  • Presence of Postsystolic Shortening Increases the Likelihood of Coronary Artery Disease: A Rest Electrocardiography-Gated Myocardial Perfusion SPECT Study. (semanticscholar.org)
  • Clinical usefulness of a novel program 'Heart Function View' for evaluating cardiac function from gated myocardial perfusion SPECT. (semanticscholar.org)
  • The method has been applied in emission tomography modalities like SPECT and PET, where there is significant attenuation along ray paths and noise statistics are relatively poor. (wikipedia.org)
  • There are several methods to assess IS, which include electrocardiography and imaging procedures such as single-photon emission computed tomography (SPECT) and echocardiography or the indirect assessment by the release of cardiac enzymes ( 2 ). (onlinejacc.org)
  • 4 . The method of claim 1 , where acquiring image data includes acquiring magnetic resonance image data, acquiring ultra sound image data, acquiring computed tomography image data, acquiring X-ray image data, acquiring PET image data, acquiring SPECT image data, or combinations thereof. (google.es)
  • Comparisons were made with manual planimetry (manual Simpson), visual assessment and automatically determined LVEF from quantitative myocardial gated single photon emission computed tomography (SPECT). (biomedcentral.com)
  • Left ventricular size and function can be assessed by many modalities such as two- and three-dimensional echocardiography, myocardial scintigraphy (gated SPECT, equilibrium radionuclide angiography), contrast ventriculography, cardiac magnetic resonance and as of late also cardiac computed tomography. (biomedcentral.com)
  • The purpose of this study was to determine how frequently and for what reasons the addition of electrocardiographically gated technetium-99m (Tc-99m) sestamibi single-photon emission computed tomographic (SPECT) images add value to nongated SPECT perfusion images. (onlinejacc.org)
  • Electrocardiographic gating of Tc-99m sestamibi SPECT images permits assessment of regional and global left ventricular function and may assist in differentiating attenuation artifacts from myocardial scar. (onlinejacc.org)
  • mean age 57.6 ± 11.5 years) underwent gated SPECT Tc-99m sestamibi imaging (212 with exercise, 63 with dipyridamole and 10 with dobutamine). (onlinejacc.org)
  • The addition of electrocardiographically gated Tc-99m sestamibi SPECT images to the reading of stress and rest perfusion images alone resulted in shifting the final scan interpretations to a more normal designation in patients with a low pretest likelihood of coronary artery disease, and to more abnormal defects consistent with coronary artery disease in patients with known coronary artery disease. (onlinejacc.org)
  • The number of "borderline normal" and "borderline abnormal" interpretations are significantly reduced when gated SPECT images are interpreted simultaneously with stress and rest perfusion images. (onlinejacc.org)
  • The addition of electrocardiographic (ECG) gating to technetium-99m (Tc-99m) sestamibi single-photon emission computed tomography (SPECT) perfusion imaging can provide additional and potentially useful information [1-17] . (onlinejacc.org)
  • Gated SPECT images can also assist in evaluating the significance of questionable perfusion defects [12] . (onlinejacc.org)
  • This invention relates generally to single photon emission computed tomography (SPECT) imaging and, more particularly, to scatter correction systems and methods for improving images generated from data collected by a SPECT scanner. (google.com)
  • Attenuation correction and gating synergistically improve the diagnostic accuracy of myocardial perfusion SPECT. (naver.com)
  • Validation of SPECT equilibrium radionuclide angiographic right ventricular parameters by cardiac magnetic resonance imaging. (naver.com)
  • We have previously developed a new method for quantitative assessment of left ventricular (LV) volumes and ejection fraction (EF) from electrocardiography-gated single photon emission computed tomography (SPECT). (nih.gov)
  • The aims of this study were to present the methodology, to validate the gated SPECT cardiac quantification (GSCQ) method in phantoms and patients, and to determine normal values of LVEF. (nih.gov)
  • These radionuclides have halflives that are often considerably shorter than those used in single photon emission computed tomography (SPECT). (paperity.org)
  • Because the gamma rays are nearly collinear (discharged at 180 to each other) and travel in opposite directions, the PET detectors can be programmed to register only events with temporal coincidence of photons that strike directly at opposing detectors.1 The result is improved spatial (4- to 6-mm) resolution when compared with SPECT, as well as temporal resolution. (paperity.org)
  • 4-D Reconstruction With Respiratory Correction for Gated Myocardial Perfusion SPECT. (umassmed.edu)
  • Comparison of methods of acquiring attenuation maps for cardiac SPECT in the presence of respiratory motion. (umassmed.edu)
  • Emphasis will be placed on the following experimental techniques: magnetic resonance imaging (MRI), electroencephalography (EEG), magnetoencephalography (MEG), positron emission tomography (PET), single photon emission computed tomography (SPECT), microscopy, and other new and evolving methods as applied to brain connectivity analysis. (liebertpub.com)
  • Myocardial perfusion imaging (MPI), using single photon emission computed tomography (SPECT) is a validated method for detecting coronary artery disease. (biomedcentral.com)
  • Acute rest single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) demonstrates a 99% negative predictive value (NPV) for acute MI, but examinations must be read critically with a resultant loss of specificity. (jaocr.org)
  • Cardiac hybrid imaging combining 3D-strain echocardiography with coronary computed tomography angiography. (uzh.ch)
  • Diagnostic accuracy of coronary opacification derived from coronary computed tomography angiography to detect ischemia: first validation versus single-photon emission computed tomography. (uzh.ch)
  • Corrected coronary opacification decrease from coronary computed tomography angiography: Validation with quantitative 13N-ammonia positron emission tomography. (uzh.ch)
  • Long-term outcome prediction by functional parameters derived from coronary computed tomography angiography. (uzh.ch)
  • Long-term prognostic performance of low-dose coronary computed tomography angiography with prospective electrocardiogram triggering. (uzh.ch)
  • Association between beta-adrenoceptor antagonist-induced sympathicolysis and severity of coronary artery disease as assessed by coronary computed tomography angiography (CCTA). (uzh.ch)
  • Quantitative plaque features from coronary computed tomography angiography to identify regional ischemia by myocardial perfusion imaging. (uzh.ch)
  • Fused cardiac hybrid imaging with coronary computed tomography angiography and positron emission tomography in patients with complex coronary artery anomalies. (uzh.ch)
  • Adaptive Statistical Iterative Reconstruction-V: Impact on Image Quality in Ultralow-Dose Coronary Computed Tomography Angiography. (uzh.ch)
  • Minimized Radiation and Contrast Agent Exposure for Coronary Computed Tomography Angiography: First Clinical Experience on a Latest Generation 256-slice Scanner. (uzh.ch)
  • Impact of monochromatic coronary computed tomography angiography from single-source dual-energy CT on coronary stenosis quantification. (uzh.ch)
  • Prevalence and characteristics of coronary artery anomalies detected by coronary computed tomography angiography in 5 634 consecutive patients in a single centre in Switzerland. (uzh.ch)
  • Mowatt G, Cook JA, Hillis GS, Walker S, Fraser C, Jia X, Waugh N. 64-slice computed tomography angiography in the diagnosis and assessment of coronary artery disease: systematic review and meta-analysis. (springer.com)
  • Lower extremity computed tomography angiography can help predict technical success of endovascular revascularization in the superficial femoral and popliteal artery. (stanford.edu)
  • Apical thinning": Relations between myocardial wall thickness and apical left ventricular tracer uptake as assessed with positron emission tomography myocardial perfusion imaging. (uzh.ch)
  • Sex differences in the long-term prognostic value of N-ammonia myocardial perfusion positron emission tomography. (uzh.ch)
  • Positron emission tomography (PET) is the gold standard for non-invasive assessment of myocardial viability and allows accurate detection of coronary artery disease by assessment of myocardial perfusion. (springer.com)
  • The purpose of this study was to evaluate a novel one-step labeled integrin α(v)β(3)-targeting positron emission tomography (PET) probe, (18)F-AlF-NOTA-PRGD2, for angiogenesis imaging in a myocardial infarction/reperfusion (MI/R) animal model. (biomedsearch.com)
  • PURPOSE: We evaluated four potential gallium-68 ((68)Ga)-labeled tracers for positron emission tomography (PET) imaging of myocardial perfusion in comparison with oxygen-15-labeled water ([(15)O]water) in healthy pigs. (biomedsearch.com)
  • The assessment of myocardial perfusion and function using PET and hybrid positron emission tomography (PET)/CT imaging is becoming more available as the cost of the technology decreases and as positron-emitting radiopharmaceuticals become more available. (medscape.com)
  • Quantitative positron emission tomography (PET) measurements of myocardial blood flow (MBF) in absolute terms (milliliters per gram per minute) offer a paradigm shift in the evaluation and management of patients with CAD. (paperity.org)
  • PET radionuclides reach a more stable configuration by the emission of a positron. (paperity.org)
  • In another embodiment, a Compton scatter positron emission tomography system is provided. (patents.com)
  • Radiolabeled microspheres were injected during occlusion for blood flow determination and 20-30 mCi of Tc-99m sestamibi was injected intravenously for cardiac imaging. (elsevier.com)
  • Myocardial risk area by ex-situ imaging was 32 ± 9% LV and did not significantly change with the addition of a chest cavity and tomographic reconstruction (post-mortem and gated imaging) or cardiac and respiratory motion (ungated imaging). (elsevier.com)
  • International Journal of Cardiac Imaging , 16 (4), 293-303. (elsevier.com)
  • Gated Blood-Pool Imaging" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
  • This graph shows the total number of publications written about "Gated Blood-Pool Imaging" by people in this website by year, and whether "Gated Blood-Pool Imaging" was a major or minor topic of these publications. (umassmed.edu)
  • Below are the most recent publications written about "Gated Blood-Pool Imaging" by people in Profiles. (wakehealth.edu)
  • Cardiac-Gated Imaging Techniques" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (sickkids.ca)
  • Timing the acquisition of imaging data to specific points in the cardiac cycle to minimize image blurring and other motion artifacts. (sickkids.ca)
  • This graph shows the total number of publications written about "Cardiac-Gated Imaging Techniques" by people in this website by year, and whether "Cardiac-Gated Imaging Techniques" was a major or minor topic of these publications. (sickkids.ca)
  • Below are the most recent publications written about "Cardiac-Gated Imaging Techniques" by people in Profiles. (sickkids.ca)
  • Dynamic imaging of the fetal heart using metric optimized gating. (sickkids.ca)
  • Ultra-low-dose computed tomography for attenuation correction of cadmium-zinc-telluride single photon emission computed tomography myocardial perfusion imaging. (uzh.ch)
  • Impact of cardiac hybrid imaging-guided patient management on clinical long-term outcome. (uzh.ch)
  • Potential hybrid PET/MR tomography may potentially facilitate the combination of information from these imaging modalities in cardiology. (springer.com)
  • ACC/AHA/ASNC guidelines for the clinical use of cardiac radionuclide imaging - executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/ASNC Committee to Revise the 1995 Guidelines for the Clinical Use of Cardiac Radionuclide Imaging). (springer.com)
  • A statement for healthcare professionals from the Cardiac Imaging Committee of the Council on Clinical Cardiology of the American Heart Association. (springer.com)
  • Role of cardiac magnetic resonance imaging in assessing ischemic and nonischemic cardiomyopathies. (biomedsearch.com)
  • A report of the American college of cardiology foundation appropriate use criteria task force, the society of cardiovascular computed tomography, the American college of radiology, the American heart association, the American society of echocardiography, the American society of nuclear cardiology, the north American society for cardiovascular imaging, the society for cardiovascular angiography and interventions, and the society for cardiovascular magnetic resonance. (springer.com)
  • The iterative Sparse Asymptotic Minimum Variance algorithm is an iterative, parameter-free superresolution tomographic reconstruction method inspired by compressed sensing, with applications in synthetic-aperture radar, computed tomography scan, and magnetic resonance imaging (MRI). (wikipedia.org)
  • Background- Contrast-enhanced cardiac magnetic resonance imaging (CMR) can determine the extent of myocardial scar from infarction (MI). (ahajournals.org)
  • Late gadolinium enhancement (LGE) imaging by contrast-enhanced cardiac magnetic resonance imaging (CMR) can detect scar due to MI unrecognized by clinical history and without a segmental wall motion abnormality (WMA). (ahajournals.org)
  • Here, we present a new technique for imaging the beating murine heart at the single cell level, based on a novel stabilizer setup combined with a gating acquisition algorithm. (pubmedcentralcanada.ca)
  • We demonstrate the utility of this technique for in vivo optical sectioning and dual-channel time-lapse fluorescence imaging of cardiac ischemia. (pubmedcentralcanada.ca)
  • Here, we present a new approach for real-time microscopic imaging, which involves a combination of motion stabilization and an algorithm for acquisition during advanced cardiopulmonary gating. (pubmedcentralcanada.ca)
  • An emission tomographic system for imaging an object of interest is described. (google.com)
  • A prototype physiologically gated micro-computed tomography (micro-CT) system based on a field emission micro-focus x-ray source has been developed for in vivo imaging of small animal models. (spie.org)
  • A statement for healthcare professionals from the Cardiac Imaging Committee of. (naver.com)
  • Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart: A statement for healthcare professionals from the Cardiac Imaging Committee of. (naver.com)
  • Clinical implementation of these techniques will have a major impact on both diagnostics and imaging assisted therapy of cardiovascular diseases and cancer. (uwm.edu)
  • Hence, existing high-resolution optical imaging modalities, including confocal microscopy, two-photon microscopy, and optical coherence tomography, are limited only to superficial tissues (~ 1 mm deep). (uwm.edu)
  • In July 2009, the Medical Advisory Secretariat (MAS) began work on Non-Invasive Cardiac Imaging Technologies for the Diagnosis of Coronary Artery Disease (CAD), an evidence-based review of the literature surrounding different cardiac imaging modalities to ensure that appropriate technologies are accessed by patients suspected of having CAD. (readbyqxmd.com)
  • This project came about when the Health Services Branch at the Ministry of Health and Long-Term Care asked MAS to provide an evidentiary platform on effectiveness and cost-effectiveness of non-invasive cardiac imaging modalities. (readbyqxmd.com)
  • We will also discuss the role of other imaging modalities currently in clinical use such as computerized tomography and magnetic resonance imaging as well as novel techniques such as contrast-enhanced ultrasound imaging. (hindawi.com)
  • US examination is considered the imaging modality of choice in the diagnosis and management of most cardiac and renal diseases. (hindawi.com)
  • Standards of care include clinical observation, serial electrocardiograms (ECGs), serial cardiac biomarkers, and provocative functional or imaging tests, with the overall goal of reducing short-term major adverse cardiovascular events (MACE). (jaocr.org)
  • Photon counting detectors (PCDs) with their low noise, high spatial and contrast resolution, and dual energy imaging capabilities are shown to be prospective candidates for Cone-Beam CT (CBCT) vascular imaging. (spie.org)
  • In the near future, artificial intelligence (AI)/machine learning will likely assist physicians with dif- ferential diagnosis of disease, treatment options suggestions, and recommendations, and, in the case of medical imaging, with cues in image interpretation. (docslide.net)
  • Cardiac imaging Introduction All medical knowledge--including the continuous addition of new and important scientific information--cannot be proc- essed and stored by a single human brain. (docslide.net)
  • Advances in computer processing speed and memory along with the advent of the microbeam former that can sample an entire crystal of the ultrasound transducer made possible the performance of 3-dimensional echocardiography in real time (RT3DE). (biomedsearch.com)
  • Echocardiography of the normal camel (Camelus dromedaries) heart: technique and cardiac dimensions. (biomedsearch.com)
  • Echocardiography and intra-cardiac dimensions have not previously been reported in adult camels despite its potential application for medical purpose. (biomedsearch.com)
  • Cardiac resynchronization therapy (CRT) can benefit patients with advanced HF and prolonged QRS. (bvsalud.org)
  • Cardiac resynchronization therapy in chronic heart failure: Effect on right ventricular function. (uzh.ch)
  • Cardiac resynchronization therapy (CRT) with biventricular pacing improves cardiac function, functional capacity and quality of life in selected patients with heart failure. (biomedsearch.com)
  • Abstract: The technological advances in computed tomography (CT) scanners and their continuously increased use have raised concern about the patient-induced risks from the CT procedures. (medworm.com)
  • Stress-rest myocardial perfusion scintigraphy and adverse cardiac events in heart failure patients. (semanticscholar.org)
  • We assessed the prognostic value of LGE and other CMR variables beyond the strongest clinical predictors and built the best overall models for major adverse cardiac events (MACE) and cardiac mortality. (ahajournals.org)
  • In patients with ischemic heart disease who undergo revascularization based on PET viability assessment with fludeoxyglucose F-18 (F-18 FDG), those with a low myocardial perfusion reserve were at an increased risk of adverse cardiac events. (medscape.com)
  • Fort du soutien de Fondation des maladies du cœur du Canada, il a travaillé comme chercheur-boursier de niveau postdoctoral à l'Hôpital Yale-New Haven, au Connecticut et a été agréé comme membre de l'American College of Cardiology en 1980, puis de l'American Society of Nuclear Cardiology en 2002. (ottawaheart.ca)
  • In nuclear emission tomography, gamma cameras or detectors typically are used for locating and displaying human glands and organs and associated abnormalities. (google.com)
  • The PET detectors are placed in a ring, surrounding the patient, and are configured to register only photon pairs that strike opposing detectors at approximately the same time, termed coincidence detection. (paperity.org)
  • Artifacts in Transmission Computed Tomography (TCT) reconstructed images with truncated projection data: Is better sampling the answer? (elsevier.com)
  • These scenarios may occur in intraoperative CT, in cardiac CT, or when metal artifacts require the exclusion of some portions of the projection data. (wikipedia.org)
  • A liposomal blood pool agent encapsulating iodine with a concentration of 65.5 mg/ml was used with a Duke Center for In Vivo Microscopy (CIVM) prototype micro-computed tomography (micro-CT) system to image the R3230AC mammary carcinoma implanted in rats. (spie.org)
  • This work, which has utilized technology such as spinning-disk confocal and multiphoton microscopy, has-along with some significant advancements in algorithms and software-unlocked our ability to image the "business end" of the cardiac vascular tree. (frontiersin.org)
  • The measurement of cardiac volumes and ejection fraction should be accurate and reproducible, easy to use, affordable, non-invasive and without radiation exposure to the patient. (biomedcentral.com)
  • A large cardiac silhouette with similar hemodynamics may reflect hemopericardium and tamponade or right ventricular (RV) MI that is compromising cardiac output. (medscape.com)
  • Extensive work has been done over recent years to improve the spatial and temporal resolution of electrocardiogram (ECG)-gated cardiac computed tomography (CT). (biomedsearch.com)
  • Secondly, we used a real-time processing approach ( Fig. 2a ) to trigger stabilized image extraction at appropriate phases of the respiratory and cardiac cycles using a retrospective electrocardiogram (ECG)-gating technique 15 . (pubmedcentralcanada.ca)
  • Additionally, the impact of ECAM has not been studied to determine management recommendations.OBJECTIVE: To address the preliminary question, we hypothesized that clinically significant arrhythmias would be detected on ECAM beyond 48hours and this would lead to clinical management changes.METHODS: A single center retrospective cohort study of ACHD patients undergoing ECAM from June 2013 to May 2016 was performed. (stanford.edu)
  • As computational cardiac models are becoming more mature, they are slowly evolving into clinical tools to better stratify HF patients, predict risk and perform treatment planning. (uni-erlangen.de)
  • Conclusions- Among patients with a clinical suspicion of coronary artery disease but without a history of MI, LGE involving a small amount of myocardium carries a high cardiac risk. (ahajournals.org)
  • In addition, LGE provides incremental prognostic value to MACE and cardiac mortality beyond common clinical, angiographic, and functional predictors. (ahajournals.org)
  • The objective was to determine the association of four clinical risk scores and coronary plaque burden as detected by computed tomography (CT) with the outcome of acute coronary syndrome (ACS) in patients with acute chest pain. (readbyqxmd.com)
  • This pilot clinical trial studies perfusion computed tomography (CT) in predicting response to treatment in patients with advanced kidney cancer. (stanford.edu)
  • Journal of Cardiovascular Computed Tomography, 10(2):135-140. (uzh.ch)
  • SCCT guidelines for performance of coronary computed tomographic angiography: a report of the Society of Cardiovascular Computed Tomography Guidelines Committee. (springer.com)
  • This study is a head-to-head comparison of predictive values for long-term cardiovascular outcomes between exercise electrocardiography (ex-ECG) and computed tomography coronary angiography (CTCA) in patients with chest pain. (readbyqxmd.com)
  • Comparison of traditional cardiovascular risk models and coronary atherosclerotic plaque as detected by computed tomography for prediction of acute coronary syndrome in patients with acute chest pain. (readbyqxmd.com)
  • Finally, the presence of significant myocardial mechanical dyssynchrony was evaluated in phase analysis on gated CZT images and the region of latest mechanical activation identified. (springernature.com)
  • PURPOSE: To evaluate the relationships among myocardial sympathetic innervation, perfusion and mechanical synchronicity assessed with cardiac cadmium-zinc-telluride (CZT) scintigraphy. (springernature.com)
  • Extended cardiac ambulatory rhythm monitoring in adults with congenital heart disease: Arrhythmia detection and impact of extended monitoring. (stanford.edu)
  • A quantitative study of motion estimation methods on 4D cardiac gated " by Wenyuan Qi, Yongyi Yang et al. (umassmed.edu)
  • Radionuclide ventriculography where scintigraphic data is acquired during repeated cardiac cycles at specific times in the cycle, using an electrocardiographic synchronizer or gating device. (umassmed.edu)
  • Extracardiac findings on computed tomography attenuation correction: Is it worth paying extra attention? (uzh.ch)
  • Because history alone is often inadequate to identify patients who may be safely discharged, 3 it is common practice to use observation and serial cardiac biomarkers for patient evaluation. (ahajournals.org)
  • Additionally, exercise testing and vasodilator stress testing are commonly used, although such testing can be performed only after an observation period, which includes serial cardiac biomarkers. (ahajournals.org)
  • METHODS: We consider the following three methods for obtaining the image motion in 4D reconstruction: (1) the Horn-Schunck optical flow equation (OFE) method, (2) a recently developed periodic OFE method, and (3) known cardiac motion derived from the NURBS-based cardiac-torso (NCAT) phantom. (umassmed.edu)
  • Methods: A chest phantom was scanned on state-of-the-art computed tomography scanners from 4 vendors at 4 dose levels (4.1 mGy, 3.0 mGy, 1.9 mGy, and 0.8 mGy). (medworm.com)
  • A review of cardiac image registration methods. (springer.com)
  • Methods: We have implemented analytical and Monte Carlo models of scintillation photons transport in scintillator segments with arbitrary trans-axial cross-section dimensions. (spie.org)
  • Diagnostic value of left ventricular dyssynchrony after exercise and at rest in the detection of multivessel coronary artery disease on single-photon emission computed tomography. (semanticscholar.org)
  • The role of nuclear medicine in assessments of cardiac dyssynchrony. (semanticscholar.org)
  • Dual cardiac-respiratory gated PET: implementation and results from a feasibility study. (springer.com)
  • Prospective respiratory-gated CT images of anesthetized free-breathing mice are collected using this scanner at 100msec temporal resolution and 10 lp/mm of 10% system MTF. (spie.org)
  • Overall, use of degrading corrections in 4D reconstruction is shown to be most effective for improving both reconstruction accuracy of the myocardium and detectability of perfusion defects in gated images. (umassmed.edu)
  • The initial evaluation of acute chest pain requires an ECG and cardiac biomarkers ( Figure 1A ). (ahajournals.org)
  • Sinha S, Sinha U, Czernin J, Porenta G, Schelbert HR. Noninvasive assessment of myocardial perfusion and metabolism: feasibility of registering gated MR and PET images. (springer.com)
  • Cardiac PET has the advantage of higher spatial resolution, temporal resolution, and, in many cases, a decreased radiation exposure to patients. (medscape.com)
  • Beat to beat left ventricular performance assessed from the equilibrium cardiac blood pool using a computerized nuclear probe. (ottawaheart.ca)
  • In 49 patients with a previous infarction or recent angiography with ≥70% stenosis, or both, the addition of gated images changed the percentage of "abnormal" scan interpretations from 78% (38 of 49) to 92% (45 of 49). (onlinejacc.org)
  • Relationship between natriuretic peptides and inflammation: proteomic evidence obtained during acute cellular cardiac allograft rejection in humans. (ottawaheart.ca)
  • Beyond this depth, high spatial resolution cannot be maintained since photons are multiply scattered. (uwm.edu)
  • In another embodiment of the invention, the invention is used to provide a high sensitivity, high spatial resolution and electronically collimated single photon emission computed tomography system which is sensitive from 81 keV to 511 keV gamma ray photons. (patents.com)
  • Types 1 and 2 include those with reduced kidney function due to either acute (type 1) or chronic cardiac dysfunction, and CRS 3 and 4 include worsening cardiac function in face of acute or chronic kidney disease, respectively. (hindawi.com)