Myocytes, Cardiac: Striated muscle cells found in the heart. They are derived from cardiac myoblasts (MYOBLASTS, CARDIAC).Cardiac Output: The volume of BLOOD passing through the HEART per unit of time. It is usually expressed as liters (volume) per minute so as not to be confused with STROKE VOLUME (volume per beat).Heart: The hollow, muscular organ that maintains the circulation of the blood.Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.Cardiac Surgical Procedures: Surgery performed on the heart.Death, Sudden, Cardiac: Unexpected rapid natural death due to cardiovascular collapse within one hour of initial symptoms. It is usually caused by the worsening of existing heart diseases. The sudden onset of symptoms, such as CHEST PAIN and CARDIAC ARRHYTHMIAS, particularly VENTRICULAR TACHYCARDIA, can lead to the loss of consciousness and cardiac arrest followed by biological death. (from Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 7th ed., 2005)Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.Cardiac Tamponade: Compression of the heart by accumulated fluid (PERICARDIAL EFFUSION) or blood (HEMOPERICARDIUM) in the PERICARDIUM surrounding the heart. The affected cardiac functions and CARDIAC OUTPUT can range from minimal to total hemodynamic collapse.Cardiac Pacing, Artificial: Regulation of the rate of contraction of the heart muscles by an artificial pacemaker.Heart Diseases: Pathological conditions involving the HEART including its structural and functional abnormalities.Myocardium: The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.Cardiac Catheterization: Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.Myocardial Contraction: Contractile activity of the MYOCARDIUM.Heart Arrest: Cessation of heart beat or MYOCARDIAL CONTRACTION. If it is treated within a few minutes, heart arrest can be reversed in most cases to normal cardiac rhythm and effective circulation.Heart Ventricles: The lower right and left chambers of the heart. The right ventricle pumps venous BLOOD into the LUNGS and the left ventricle pumps oxygenated blood into the systemic arterial circulation.Myoblasts, Cardiac: Precursor cells destined to differentiate into cardiac myocytes (MYOCYTES, CARDIAC).Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.Cardiomyopathies: A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).Cardiac Myosins: Myosin type II isoforms found in cardiac muscle.Cardiac Imaging Techniques: Visualization of the heart structure and cardiac blood flow for diagnostic evaluation or to guide cardiac procedures via techniques including ENDOSCOPY (cardiac endoscopy, sometimes refered to as cardioscopy), RADIONUCLIDE IMAGING; MAGNETIC RESONANCE IMAGING; TOMOGRAPHY; or ULTRASONOGRAPHY.Electrocardiography: Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.Cardiac Glycosides: Cyclopentanophenanthrenes with a 5- or 6-membered lactone ring attached at the 17-position and SUGARS attached at the 3-position. Plants they come from have long been used in congestive heart failure. They increase the force of cardiac contraction without significantly affecting other parameters, but are very toxic at larger doses. Their mechanism of action usually involves inhibition of the NA(+)-K(+)-EXCHANGING ATPASE and they are often used in cell biological studies for that purpose.Heart Rate: The number of times the HEART VENTRICLES contract per unit of time, usually per minute.Echocardiography: Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.Cardiac Output, Low: A state of subnormal or depressed cardiac output at rest or during stress. It is a characteristic of CARDIOVASCULAR DISEASES, including congenital, valvular, rheumatic, hypertensive, coronary, and cardiomyopathic. The serious form of low cardiac output is characterized by marked reduction in STROKE VOLUME, and systemic vasoconstriction resulting in cold, pale, and sometimes cyanotic extremities.Out-of-Hospital Cardiac Arrest: Occurrence of heart arrest in an individual when there is no immediate access to medical personnel or equipment.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Hemodynamics: The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).Cardiac Volume: The volume of the HEART, usually relating to the volume of BLOOD contained within it at various periods of the cardiac cycle. The amount of blood ejected from a ventricle at each beat is STROKE VOLUME.Ventricular Remodeling: The geometric and structural changes that the HEART VENTRICLES undergo, usually following MYOCARDIAL INFARCTION. It comprises expansion of the infarct and dilatation of the healthy ventricle segments. While most prevalent in the left ventricle, it can also occur in the right ventricle.Heart Transplantation: The transference of a heart from one human or animal to another.Troponin I: One of the three polypeptide chains that make up the TROPONIN complex. It inhibits F-actin-myosin interactions.Ventricular Function, Left: The hemodynamic and electrophysiological action of the left HEART VENTRICLE. Its measurement is an important aspect of the clinical evaluation of patients with heart disease to determine the effects of the disease on cardiac performance.Heart Defects, Congenital: Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.Stroke Volume: The amount of BLOOD pumped out of the HEART per beat, not to be confused with cardiac output (volume/time). It is calculated as the difference between the end-diastolic volume and the end-systolic volume.Blood Pressure: PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.Cardiac Resynchronization Therapy: The restoration of the sequential order of contraction and relaxation of the HEART ATRIA and HEART VENTRICLES by atrio-biventricular pacing.Heart Function Tests: Examinations used to diagnose and treat heart conditions.Troponin T: One of the three polypeptide chains that make up the TROPONIN complex. It is a cardiac-specific protein that binds to TROPOMYOSIN. It is released from damaged or injured heart muscle cells (MYOCYTES, CARDIAC). Defects in the gene encoding troponin T result in FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.Heart Conduction System: An impulse-conducting system composed of modified cardiac muscle, having the power of spontaneous rhythmicity and conduction more highly developed than the rest of the heart.Cardiopulmonary Resuscitation: The artificial substitution of heart and lung action as indicated for HEART ARREST resulting from electric shock, DROWNING, respiratory arrest, or other causes. The two major components of cardiopulmonary resuscitation are artificial ventilation (RESPIRATION, ARTIFICIAL) and closed-chest CARDIAC MASSAGE.Heart Neoplasms: Tumors in any part of the heart. They include primary cardiac tumors and metastatic tumors to the heart. Their interference with normal cardiac functions can cause a wide variety of symptoms including HEART FAILURE; CARDIAC ARRHYTHMIAS; or EMBOLISM.Cardiac Care Facilities: Institutions specializing in the care of patients with heart disorders.Dogs: The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)Cardiomyopathy, Dilated: A form of CARDIAC MUSCLE disease that is characterized by ventricular dilation, VENTRICULAR DYSFUNCTION, and HEART FAILURE. Risk factors include SMOKING; ALCOHOL DRINKING; HYPERTENSION; INFECTION; PREGNANCY; and mutations in the LMNA gene encoding LAMIN TYPE A, a NUCLEAR LAMINA protein.Ventricular Dysfunction, Left: A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.Cardiotonic Agents: Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE).Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Cardiac Electrophysiology: The study of the electrical activity and characteristics of the HEART; MYOCARDIUM; and CARDIOMYOCYTES.Models, Cardiovascular: Theoretical representations that simulate the behavior or activity of the cardiovascular system, processes, or phenomena; includes the use of mathematical equations, computers and other electronic equipment.Fibrosis: Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.Rats, Sprague-Dawley: A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.Fetal Heart: The heart of the fetus of any viviparous animal. It refers to the heart in the postembryonic period and is differentiated from the embryonic heart (HEART/embryology) only on the basis of time.Calcium: A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.Heart Atria: The chambers of the heart, to which the BLOOD returns from the circulation.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Ventricular Function: The hemodynamic and electrophysiological action of the HEART VENTRICLES.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Cells, Cultured: Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.Heart Injuries: General or unspecified injuries to the heart.Cardiopulmonary Bypass: Diversion of the flow of blood from the entrance of the right atrium directly to the aorta (or femoral artery) via an oxygenator thus bypassing both the heart and lungs.Troponin: One of the minor protein components of skeletal muscle. Its function is to serve as the calcium-binding component in the troponin-tropomyosin B-actin-myosin complex by conferring calcium sensitivity to the cross-linked actin and myosin filaments.Hypertrophy, Left Ventricular: Enlargement of the LEFT VENTRICLE of the heart. This increase in ventricular mass is attributed to sustained abnormal pressure or volume loads and is a contributor to cardiovascular morbidity and mortality.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Myocarditis: Inflammatory processes of the muscular walls of the heart (MYOCARDIUM) which result in injury to the cardiac muscle cells (MYOCYTES, CARDIAC). Manifestations range from subclinical to sudden death (DEATH, SUDDEN). Myocarditis in association with cardiac dysfunction is classified as inflammatory CARDIOMYOPATHY usually caused by INFECTION, autoimmune diseases, or responses to toxic substances. Myocarditis is also a common cause of DILATED CARDIOMYOPATHY and other cardiomyopathies.Mice, Transgenic: Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.Sarcomeres: The repeating contractile units of the MYOFIBRIL, delimited by Z bands along its length.Atrial Natriuretic Factor: A potent natriuretic and vasodilatory peptide or mixture of different-sized low molecular weight PEPTIDES derived from a common precursor and secreted mainly by the HEART ATRIUM. All these peptides share a sequence of about 20 AMINO ACIDS.Muscle Proteins: The protein constituents of muscle, the major ones being ACTINS and MYOSINS. More than a dozen accessory proteins exist including TROPONIN; TROPOMYOSIN; and DYSTROPHIN.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Mitochondria, Heart: The mitochondria of the myocardium.Heart Valves: Flaps of tissue that prevent regurgitation of BLOOD from the HEART VENTRICLES to the HEART ATRIA or from the PULMONARY ARTERIES or AORTA to the ventricles.Pericardium: A conical fibro-serous sac surrounding the HEART and the roots of the great vessels (AORTA; VENAE CAVAE; PULMONARY ARTERY). Pericardium consists of two sacs: the outer fibrous pericardium and the inner serous pericardium. The latter consists of an outer parietal layer facing the fibrous pericardium, and an inner visceral layer (epicardium) resting next to the heart, and a pericardial cavity between these two layers.Predictive Value of Tests: In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.Rats, Wistar: A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.Pacemaker, Artificial: A device designed to stimulate, by electric impulses, contraction of the heart muscles. It may be temporary (external) or permanent (internal or internal-external).Edema, Cardiac: Abnormal fluid retention by the body due to impaired cardiac function or heart failure. It is usually characterized by increase in venous and capillary pressure, and swollen legs when standing. It is different from the generalized edema caused by renal dysfunction (NEPHROTIC SYNDROME).Biological Markers: Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.Mice, Inbred C57BLMagnetic Resonance Imaging, Cine: A type of imaging technique used primarily in the field of cardiology. By coordinating the fast gradient-echo MRI sequence with retrospective ECG-gating, numerous short time frames evenly spaced in the cardiac cycle are produced. These images are laced together in a cinematic display so that wall motion of the ventricles, valve motion, and blood flow patterns in the heart and great vessels can be visualized.Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.Ventricular Fibrillation: A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.Animals, Newborn: Refers to animals in the period of time just after birth.Coronary Circulation: The circulation of blood through the CORONARY VESSELS of the HEART.Natriuretic Peptide, Brain: A PEPTIDE that is secreted by the BRAIN and the HEART ATRIA, stored mainly in cardiac ventricular MYOCARDIUM. It can cause NATRIURESIS; DIURESIS; VASODILATION; and inhibits secretion of RENIN and ALDOSTERONE. It improves heart function. It contains 32 AMINO ACIDS.Myocardial Reperfusion Injury: Damage to the MYOCARDIUM resulting from MYOCARDIAL REPERFUSION (restoration of blood flow to ischemic areas of the HEART.) Reperfusion takes place when there is spontaneous thrombolysis, THROMBOLYTIC THERAPY, collateral flow from other coronary vascular beds, or reversal of vasospasm.Cardiomyopathy, Hypertrophic: A form of CARDIAC MUSCLE disease, characterized by left and/or right ventricular hypertrophy (HYPERTROPHY, LEFT VENTRICULAR; HYPERTROPHY, RIGHT VENTRICULAR), frequent asymmetrical involvement of the HEART SEPTUM, and normal or reduced left ventricular volume. Risk factors include HYPERTENSION; AORTIC STENOSIS; and gene MUTATION; (FAMILIAL HYPERTROPHIC CARDIOMYOPATHY).Mice, Knockout: Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.Ventricular Pressure: The pressure within a CARDIAC VENTRICLE. Ventricular pressure waveforms can be measured in the beating heart by catheterization or estimated using imaging techniques (e.g., DOPPLER ECHOCARDIOGRAPHY). The information is useful in evaluating the function of the MYOCARDIUM; CARDIAC VALVES; and PERICARDIUM, particularly with simultaneous measurement of other (e.g., aortic or atrial) pressures.Risk Assessment: The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)Coronary Artery Bypass: Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.Sarcolemma: The excitable plasma membrane of a muscle cell. (Glick, Glossary of Biochemistry and Molecular Biology, 1990)Myosin Heavy Chains: The larger subunits of MYOSINS. The heavy chains have a molecular weight of about 230 kDa and each heavy chain is usually associated with a dissimilar pair of MYOSIN LIGHT CHAINS. The heavy chains possess actin-binding and ATPase activity.Coronary Vessels: The veins and arteries of the HEART.Signal Transduction: The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.Thermodilution: Measurement of blood flow based on induction at one point of the circulation of a known change in the intravascular heat content of flowing blood and detection of the resultant change in temperature at a point downstream.Diastole: Post-systolic relaxation of the HEART, especially the HEART VENTRICLES.Echocardiography, Doppler: Measurement of intracardiac blood flow using an M-mode and/or two-dimensional (2-D) echocardiogram while simultaneously recording the spectrum of the audible Doppler signal (e.g., velocity, direction, amplitude, intensity, timing) reflected from the moving column of red blood cells.GATA4 Transcription Factor: A GATA transcription factor that is expressed in the MYOCARDIUM of developing heart and has been implicated in the differentiation of CARDIAC MYOCYTES. GATA4 is activated by PHOSPHORYLATION and regulates transcription of cardiac-specific genes.Ventricular Dysfunction: A condition in which HEART VENTRICLES exhibit impaired function.Thoracic Surgery: A surgical specialty concerned with diagnosis and treatment of disorders of the heart, lungs, and esophagus. Two major types of thoracic surgery are classified as pulmonary and cardiovascular.Systole: Period of contraction of the HEART, especially of the HEART VENTRICLES.Pericardial Effusion: Fluid accumulation within the PERICARDIUM. Serous effusions are associated with pericardial diseases. Hemopericardium is associated with trauma. Lipid-containing effusion (chylopericardium) results from leakage of THORACIC DUCT. Severe cases can lead to CARDIAC TAMPONADE.NAV1.5 Voltage-Gated Sodium Channel: A voltage-gated sodium channel subtype that mediates the sodium ion PERMEABILITY of CARDIOMYOCYTES. Defects in the SCN5A gene, which codes for the alpha subunit of this sodium channel, are associated with a variety of CARDIAC DISEASES that result from loss of sodium channel function.Rabbits: The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.Endomyocardial Fibrosis: A condition characterized by the thickening of the ventricular ENDOCARDIUM and subendocardium (MYOCARDIUM), seen mostly in children and young adults in the TROPICAL CLIMATE. The fibrous tissue extends from the apex toward and often involves the HEART VALVES causing restrictive blood flow into the respective ventricles (CARDIOMYOPATHY, RESTRICTIVE).Prognosis: A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.Adrenergic beta-Antagonists: Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.RNA, Messenger: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.Exercise Test: Controlled physical activity which is performed in order to allow assessment of physiological functions, particularly cardiovascular and pulmonary, but also aerobic capacity. Maximal (most intense) exercise is usually required but submaximal exercise is also used.Autonomic Nervous System: The ENTERIC NERVOUS SYSTEM; PARASYMPATHETIC NERVOUS SYSTEM; and SYMPATHETIC NERVOUS SYSTEM taken together. Generally speaking, the autonomic nervous system regulates the internal environment during both peaceful activity and physical or emotional stress. Autonomic activity is controlled and integrated by the CENTRAL NERVOUS SYSTEM, especially the HYPOTHALAMUS and the SOLITARY NUCLEUS, which receive information relayed from VISCERAL AFFERENTS.Electrophysiologic Techniques, Cardiac: Methods to induce and measure electrical activities at specific sites in the heart to diagnose and treat problems with the heart's electrical system.Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.Creatine Kinase: A transferase that catalyzes formation of PHOSPHOCREATINE from ATP + CREATINE. The reaction stores ATP energy as phosphocreatine. Three cytoplasmic ISOENZYMES have been identified in human tissues: the MM type from SKELETAL MUSCLE, the MB type from myocardial tissue and the BB type from nervous tissue as well as a mitochondrial isoenzyme. Macro-creatine kinase refers to creatine kinase complexed with other serum proteins.Bradycardia: Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.Vascular Resistance: The force that opposes the flow of BLOOD through a vascular bed. It is equal to the difference in BLOOD PRESSURE across the vascular bed divided by the CARDIAC OUTPUT.Oxygen Consumption: The rate at which oxygen is used by a tissue; microliters of oxygen STPD used per milligram of tissue per hour; the rate at which oxygen enters the blood from alveolar gas, equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body. (Stedman, 25th ed, p346)Action Potentials: Abrupt changes in the membrane potential that sweep along the CELL MEMBRANE of excitable cells in response to excitation stimuli.Muscle Cells: Mature contractile cells, commonly known as myocytes, that form one of three kinds of muscle. The three types of muscle cells are skeletal (MUSCLE FIBERS, SKELETAL), cardiac (MYOCYTES, CARDIAC), and smooth (MYOCYTES, SMOOTH MUSCLE). They are derived from embryonic (precursor) muscle cells called MYOBLASTS.Coronary Artery Disease: Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.Myofibrils: The long cylindrical contractile organelles of STRIATED MUSCLE cells composed of ACTIN FILAMENTS; MYOSIN filaments; and other proteins organized in arrays of repeating units called SARCOMERES .Sarcoplasmic Reticulum Calcium-Transporting ATPases: Calcium-transporting ATPases that catalyze the active transport of CALCIUM into the SARCOPLASMIC RETICULUM vesicles from the CYTOPLASM. They are primarily found in MUSCLE CELLS and play a role in the relaxation of MUSCLES.Resuscitation: The restoration to life or consciousness of one apparently dead. (Dorland, 27th ed)Endocardium: The innermost layer of the heart, comprised of endothelial cells.Adrenergic beta-Agonists: Drugs that selectively bind to and activate beta-adrenergic receptors.Troponin C: One of the three polypeptide chains that make up the TROPONIN complex of skeletal muscle. It is a calcium-binding protein.Vagus Nerve: The 10th cranial nerve. The vagus is a mixed nerve which contains somatic afferents (from skin in back of the ear and the external auditory meatus), visceral afferents (from the pharynx, larynx, thorax, and abdomen), parasympathetic efferents (to the thorax and abdomen), and efferents to striated muscle (of the larynx and pharynx).Anti-Arrhythmia Agents: Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.Ventricular Myosins: Isoforms of MYOSIN TYPE II, specifically found in the ventricular muscle of the HEART. Defects in the genes encoding ventricular myosins result in FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.Receptors, Adrenergic, beta: One of two major pharmacologically defined classes of adrenergic receptors. The beta adrenergic receptors play an important role in regulating CARDIAC MUSCLE contraction, SMOOTH MUSCLE relaxation, and GLYCOGENOLYSIS.Defibrillators, Implantable: Implantable devices which continuously monitor the electrical activity of the heart and automatically detect and terminate ventricular tachycardia (TACHYCARDIA, VENTRICULAR) and VENTRICULAR FIBRILLATION. They consist of an impulse generator, batteries, and electrodes.Organ Size: The measurement of an organ in volume, mass, or heaviness.Death: Irreversible cessation of all bodily functions, manifested by absence of spontaneous breathing and total loss of cardiovascular and cerebral functions.Cardiac Resynchronization Therapy Devices: Types of artificial pacemakers with implantable leads to be placed at multiple intracardial sites. They are used to treat various cardiac conduction disturbances which interfere with the timing of contraction of the ventricles. They may or may not include defibrillating electrodes (IMPLANTABLE DEFIBRILLATORS) as well.Ryanodine Receptor Calcium Release Channel: A tetrameric calcium release channel in the SARCOPLASMIC RETICULUM membrane of SMOOTH MUSCLE CELLS, acting oppositely to SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES. It is important in skeletal and cardiac excitation-contraction coupling and studied by using RYANODINE. Abnormalities are implicated in CARDIAC ARRHYTHMIAS and MUSCULAR DISEASES.Advanced Cardiac Life Support: The use of sophisticated methods and equipment to treat cardiopulmonary arrest. Advanced Cardiac Life Support (ACLS) includes the use of specialized equipment to maintain the airway, early defibrillation and pharmacological therapy.Myxoma: A benign neoplasm derived from connective tissue, consisting chiefly of polyhedral and stellate cells that are loosely embedded in a soft mucoid matrix, thereby resembling primitive mesenchymal tissue. It occurs frequently intramuscularly where it may be mistaken for a sarcoma. It appears also in the jaws and the skin. (From Stedman, 25th ed)Papillary Muscles: Conical muscular projections from the walls of the cardiac ventricles, attached to the cusps of the atrioventricular valves by the chordae tendineae.Coronary Angiography: Radiography of the vascular system of the heart muscle after injection of a contrast medium.Angiotensin II: An octapeptide that is a potent but labile vasoconstrictor. It is produced from angiotensin I after the removal of two amino acids at the C-terminal by ANGIOTENSIN CONVERTING ENZYME. The amino acid in position 5 varies in different species. To block VASOCONSTRICTION and HYPERTENSION effect of angiotensin II, patients are often treated with ACE INHIBITORS or with ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS.Dose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.Calcium Channels, L-Type: Long-lasting voltage-gated CALCIUM CHANNELS found in both excitable and nonexcitable tissue. They are responsible for normal myocardial and vascular smooth muscle contractility. Five subunits (alpha-1, alpha-2, beta, gamma, and delta) make up the L-type channel. The alpha-1 subunit is the binding site for calcium-based antagonists. Dihydropyridine-based calcium antagonists are used as markers for these binding sites.Tachycardia, Ventricular: An abnormally rapid ventricular rhythm usually in excess of 150 beats per minute. It is generated within the ventricle below the BUNDLE OF HIS, either as autonomic impulse formation or reentrant impulse conduction. Depending on the etiology, onset of ventricular tachycardia can be paroxysmal (sudden) or nonparoxysmal, its wide QRS complexes can be uniform or polymorphic, and the ventricular beating may be independent of the atrial beating (AV dissociation).Purkinje Fibers: Modified cardiac muscle fibers composing the terminal portion of the heart conduction system.3-Iodobenzylguanidine: A guanidine analog with specific affinity for tissues of the sympathetic nervous system and related tumors. The radiolabeled forms are used as antineoplastic agents and radioactive imaging agents. (Merck Index, 12th ed) MIBG serves as a neuron-blocking agent which has a strong affinity for, and retention in, the adrenal medulla and also inhibits ADP-ribosyltransferase.Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.Reproducibility of Results: The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.Guinea Pigs: A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research.Heart Valve Diseases: Pathological conditions involving any of the various HEART VALVES and the associated structures (PAPILLARY MUSCLES and CHORDAE TENDINEAE).Sodium Channels: Ion channels that specifically allow the passage of SODIUM ions. A variety of specific sodium channel subtypes are involved in serving specialized functions such as neuronal signaling, CARDIAC MUSCLE contraction, and KIDNEY function.Cardiovascular System: The HEART and the BLOOD VESSELS by which BLOOD is pumped and circulated through the body.Electric Countershock: An electrical current applied to the HEART to terminate a disturbance of its rhythm, ARRHYTHMIAS, CARDIAC. (Stedman, 25th ed)Gene Expression Regulation: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.Myosins: A diverse superfamily of proteins that function as translocating proteins. They share the common characteristics of being able to bind ACTINS and hydrolyze MgATP. Myosins generally consist of heavy chains which are involved in locomotion, and light chains which are involved in regulation. Within the structure of myosin heavy chain are three domains: the head, the neck and the tail. The head region of the heavy chain contains the actin binding domain and MgATPase domain which provides energy for locomotion. The neck region is involved in binding the light-chains. The tail region provides the anchoring point that maintains the position of the heavy chain. The superfamily of myosins is organized into structural classes based upon the type and arrangement of the subunits they contain.Heart Block: Impaired conduction of cardiac impulse that can occur anywhere along the conduction pathway, such as between the SINOATRIAL NODE and the right atrium (SA block) or between atria and ventricles (AV block). Heart blocks can be classified by the duration, frequency, or completeness of conduction block. Reversibility depends on the degree of structural or functional defects.Norepinephrine: Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.Sodium-Calcium Exchanger: An electrogenic ion exchange protein that maintains a steady level of calcium by removing an amount of calcium equal to that which enters the cells. It is widely distributed in most excitable membranes, including the brain and heart.Defibrillators: Cardiac electrical stimulators that apply brief high-voltage electroshocks to the HEART. These stimulators are used to restore normal rhythm and contractile function in hearts of patients who are experiencing VENTRICULAR FIBRILLATION or ventricular tachycardia (TACHYCARDIA, VENTRICULAR) that is not accompanied by a palpable PULSE. Some defibrillators may also be used to correct certain noncritical dysrhythmias (called synchronized defibrillation or CARDIOVERSION), using relatively low-level discharges synchronized to the patient's ECG waveform. (UMDNS, 2003)Hypothermia, Induced: Abnormally low BODY TEMPERATURE that is intentionally induced in warm-blooded animals by artificial means. In humans, mild or moderate hypothermia has been used to reduce tissue damages, particularly after cardiac or spinal cord injuries and during subsequent surgeries.Analysis of Variance: A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.Magnetic Resonance Imaging: Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.Cardiology: The study of the heart, its physiology, and its functions.Emergency Medical Services: Services specifically designed, staffed, and equipped for the emergency care of patients.Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)Electrophysiology: The study of the generation and behavior of electrical charges in living organisms particularly the nervous system and the effects of electricity on living organisms.Calcium Signaling: Signal transduction mechanisms whereby calcium mobilization (from outside the cell or from intracellular storage pools) to the cytoplasm is triggered by external stimuli. Calcium signals are often seen to propagate as waves, oscillations, spikes, sparks, or puffs. The calcium acts as an intracellular messenger by activating calcium-responsive proteins.Models, Animal: Non-human animals, selected because of specific characteristics, for use in experimental research, teaching, or testing.Heart Massage: Rhythmic compression of the heart by pressure applied manually over the sternum (closed heart massage) or directly to the heart through an opening in the chest wall (open heart massage). It is done to reinstate and maintain circulation. (Dorland, 28th ed)Cardiac-Gated Imaging Techniques: Timing the acquisition of imaging data to specific points in the cardiac cycle to minimize image blurring and other motion artifacts.Electrocardiography, Ambulatory: Method in which prolonged electrocardiographic recordings are made on a portable tape recorder (Holter-type system) or solid-state device ("real-time" system), while the patient undergoes normal daily activities. It is useful in the diagnosis and management of intermittent cardiac arrhythmias and transient myocardial ischemia.Calcium-Binding Proteins: Proteins to which calcium ions are bound. They can act as transport proteins, regulator proteins, or activator proteins. They typically contain EF HAND MOTIFS.Gene Expression: The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.Rhabdomyoma: A benign tumor derived from striated muscle. It is extremely rare, generally occurring in the tongue, neck muscles, larynx, uvula, nasal cavity, axilla, vulva, and heart. These tumors are treated by simple excision. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1354)Perfusion: Treatment process involving the injection of fluid into an organ or tissue.Cardiography, Impedance: A type of impedance plethysmography in which bioelectrical impedance is measured between electrodes positioned around the neck and around the lower thorax. It is used principally to calculate stroke volume and cardiac volume, but it is also related to myocardial contractility, thoracic fluid content, and circulation to the extremities.Death, Sudden: The abrupt cessation of all vital bodily functions, manifested by the permanent loss of total cerebral, respiratory, and cardiovascular functions.Cardiovascular Agents: Agents that affect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume.Phosphorylation: The introduction of a phosphoryl group into a compound through the formation of an ester bond between the compound and a phosphorus moiety.Phenotype: The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.Blood Circulation: The movement of the BLOOD as it is pumped through the CARDIOVASCULAR SYSTEM.Swine: Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).Muscle, Skeletal: A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.Survival Rate: The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.Monitoring, Physiologic: The continuous measurement of physiological processes, blood pressure, heart rate, renal output, reflexes, respiration, etc., in a patient or experimental animal; includes pharmacologic monitoring, the measurement of administered drugs or their metabolites in the blood, tissues, or urine.Dobutamine: A catecholamine derivative with specificity for BETA-1 ADRENERGIC RECEPTORS. It is commonly used as a cardiotonic agent after CARDIAC SURGERY and during DOBUTAMINE STRESS ECHOCARDIOGRAPHY.Postoperative Period: The period following a surgical operation.Membrane Potentials: The voltage differences across a membrane. For cellular membranes they are computed by subtracting the voltage measured outside the membrane from the voltage measured inside the membrane. They result from differences of inside versus outside concentration of potassium, sodium, chloride, and other ions across cells' or ORGANELLES membranes. For excitable cells, the resting membrane potentials range between -30 and -100 millivolts. Physical, chemical, or electrical stimuli can make a membrane potential more negative (hyperpolarization), or less negative (depolarization).Fibroblasts: Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.Atrial Fibrillation: Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.Diabetic Cardiomyopathies: Diabetes complications in which VENTRICULAR REMODELING in the absence of CORONARY ATHEROSCLEROSIS and hypertension results in cardiac dysfunctions, typically LEFT VENTRICULAR DYSFUNCTION. The changes also result in myocardial hypertrophy, myocardial necrosis and fibrosis, and collagen deposition due to impaired glucose tolerance.Cardiac Output, High: A state of elevated cardiac output due to conditions of either increased hemodynamic demand or reduced cardiac oxygen output. These conditions may include ANEMIA; ARTERIOVENOUS FISTULA; THYROTOXICOSIS; PREGNANCY; EXERCISE; FEVER; and ANOXIA. In time, compensatory changes of the heart can lead to pathological form of high cardiac output and eventual HEART FAILURE.Tachycardia: Abnormally rapid heartbeat, usually with a HEART RATE above 100 beats per minute for adults. Tachycardia accompanied by disturbance in the cardiac depolarization (cardiac arrhythmia) is called tachyarrhythmia.Potassium Channels: Cell membrane glycoproteins that are selectively permeable to potassium ions. At least eight major groups of K channels exist and they are made up of dozens of different subunits.Blotting, Western: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.Heart Arrest, Induced: A procedure to stop the contraction of MYOCARDIUM during HEART SURGERY. It is usually achieved with the use of chemicals (CARDIOPLEGIC SOLUTIONS) or cold temperature (such as chilled perfusate).Patch-Clamp Techniques: An electrophysiologic technique for studying cells, cell membranes, and occasionally isolated organelles. All patch-clamp methods rely on a very high-resistance seal between a micropipette and a membrane; the seal is usually attained by gentle suction. The four most common variants include on-cell patch, inside-out patch, outside-out patch, and whole-cell clamp. Patch-clamp methods are commonly used to voltage clamp, that is control the voltage across the membrane and measure current flow, but current-clamp methods, in which the current is controlled and the voltage is measured, are also used.

Initial results of cardiac imaging at 7 Tesla. (1/150)

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Three-dimensional, in vivo MRI with self-gating and image coregistration in the mouse. (2/150)

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Motion of the cerebellar tonsils in the foramen magnum during the cardiac cycle. (3/150)

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Multiscale deformable registration for dual-energy x-ray imaging. (4/150)

Dual-energy (DE) imaging of the chest improves the conspicuity of subtle lung nodules through the removal of overlying anatomical noise. Recent work has shown double-shot DE imaging (i.e., successive acquisition of low- and high-energy projections) to provide detective quantum efficiency, spectral separation (and therefore contrast), and radiation dose superior to single-shot DE imaging configurations (e.g., with a CR cassette). However, the temporal separation between high-energy (HE) and low-energy (LE) image acquisition can result in motion artifacts in the DE images, reducing image quality and diminishing diagnostic performance. This has motivated the development of a deformable registration technique that aligns the HE image onto the LE image before DE decomposition. The algorithm reported here operates in multiple passes at progressively smaller scales and increasing resolution. The first pass addresses large-scale motion by means of mutual information optimization, while successive passes (2-4) correct misregistration at finer scales by means of normalized cross correlation. Evaluation of registration performance in 129 patients imaged using an experimental DE imaging prototype demonstrated a statistically significant improvement in image alignment. Specific to the cardiac region, the registration algorithm was found to outperform a simple cardiac-gating system designed to trigger both HE and LE exposures during diastole. Modulation transfer function (MTF) analysis reveals additional advantages in DE image quality in terms of noise reduction and edge enhancement. This algorithm could offer an important tool in enhancing DE image quality and potentially improving diagnostic performance.  (+info)

Whole-chest 64-MDCT of emergency department patients with nonspecific chest pain: Radiation dose and coronary artery image quality with prospective ECG triggering versus retrospective ECG gating. (5/150)

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Optical flow estimation for a periodic image sequence. (6/150)

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High spatial and temporal resolution cardiac cine MRI from retrospective reconstruction of data acquired in real time using motion correction and resorting. (7/150)

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Intrinsic gating for small-animal computed tomography: a robust ECG-less paradigm for deriving cardiac phase information and functional imaging. (8/150)

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CT technology continues to rapidly evolve, especially in the area of reducing radiation dose while preserving IQ. In the present study, we used a high-pitch, ECG-triggered scan mode on a second-generation DSCT scanner to assess PV and LA anatomy in patients with SR or AF. Our results show that PV imaging can be performed with a low median radiation dose of 1.4 mSv and achieves good to excellent CT IQ. CT scanning is feasible, with no difference in IQ between patients in AF compared with SR, without the need for heart rate-lowering agents. When compared with prior standard CT protocols, we observed a remarkable reduction in radiation dose for both patients with SR and AF with this high-pitch CT protocol. Scan time acquisition was much faster with this low radiation CT scanning technique compared with MRI, with excellent agreement of PV anatomy between the 2 imaging modalities.. Thorough assessment of PV and LA anatomy with a noninvasive imaging modality, such as CT, is important in patients with ...
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Cardiac CT clinics in Krong Preah Sihanouk at the best price. Find doctors, specialized in Cardiology and compare prices, costs and reviews.
Wolf-Parkinson-White (WPW) is one of the few clinical diseases that is mainly diagnosed by the electrocardiogram. One of the ultimate goals of modern medicine is to find a method to prevent disease. One of the best examples is catheter ablation of the Accessory Tracts in patients with WPW that will prevent tachyarrhythmias and Sudden Cardiac Death (SCD) in more than 95% of the patients. In patients with WPW, catheter ablation is the treatment of choice in the highly symptomatic patient with severe arrhythmias. A major challenge today is to ascertain the benefits versus the risks of doing catheter ablation in the asymptomatic patient with WPW. In this issue of Circulation, Obeyesekere et al1 using meta-analysis studied the risk of arrhythmia and sudden death in patients with asymptomatic pre-excitation and summarized the breadth of published evidence regarding the risks and benefits of catheter ablation in the asymptomatic patient. This study is an important milestone in the history of WPW, since ...
BACKGROUND: Positron emission tomography scanners with retractable septa allow both 3-dimensional (3D) and 2-dimensional (2D) acquisition modes. The study aim was to directly compare 2D and 3D acquisition modes for the evaluation of absolute myocardial blood flow (MBF) over a wide range of flow values. METHODS AND RESULTS: Instrumentation was used in 4 dogs to reduce the left circumflex artery lumen by greater than 75%. During infusion of adenosine, MBF was measured with both 2D and 3D dynamic acquisition and both oxygen 15 water and nitrogen 13 ammonia. Injected activities were 333 MBq and 111 MBq for 2D acquisition and 3D acquisition, respectively. Data were reconstructed by analytic methods, and MBF was assessed by use of an 18-segment model. MBF values ranged from 0.4 to 5.8 mL x g(-1) x min(-1) with O-15 water and from 0.3 to 3.9 mL x g(-1) x min(-1) with N-13 ammonia. No significant differences were observed in absolute MBF values obtained with the 2 acquisition modes, regardless of the ...
March 4, 2011 -- VIENNA - Nearly one in five coronary CT angiography scans acquired with an emerging high-pitch dual-source CT angiography (DSCTA) protocol needs to be repeated. But the low-dose acquisitions possible mean even repeated scans have lower overall doses than comparable 64-detector-row CTA scans, researchers reported at the European Congress of Radiology. Discuss ...
Read Cardiac CT by Marc Dewey with Rakuten Kobo. Cardiac computed tomography (CT) has become a highly accurate diagnostic modality that continues to attract increasing a...
Cardiac Imaging - Viewing requires Macromedia Flash plug-in. Cardiac CT STR 6001 Cardiac CT: Anatomy and Anatomic Pitfalls (2006)Lynn S. Broderick, MD STR 6002 Cardiac CT: Principles and Techniques (2006)Benoit Desjardins, MD STR ...
RADAR is a simple acquisition mode that acquires both MRM and full scan MS simultaneously, a unique capability that can both simplify and accelerate development of robust methods.
Background - Autograft regurgitation and root dilatation after the Ross procedure is of major concern. We reviewed data from the German Ross Registry to document the development of autograft regurgitation and root dilatation with time and also to compare 2 different techniques of autograft implantation. Methods and Results - Between 1990 and 2006 1014 patients (786 men, 228 women; mean age 41.2 +/- 15.3 years) underwent the Ross procedure using 2 different implantation techniques (subcoronary, n = 521; root replacement, n = 493). Clinical and serial echocardiographic follow up was performed preoperatively and thereafter annually (mean follow up 4.41 +/- 3.11 years, median 3.93 years, range 0 to 16.04 years; 5012 patient- years). For statistical analysis of serial echocardiograms, a hierarchical multilevel modeling technique was applied. Eight early and 28 late deaths were observed. Pulmonary autograft reoperations were required in 35 patients. Initial autograft regurgitation grade was 0.49 (root ...
Sydney Adventist Hospital is a modern acute care facility with all diagnostic and therapeutic services. The San offers a wide range of specialties including cardiac care, maternity and more.
BACKGROUND: Patients with treated HIV infection have clear survival benefits although with increased cardiac morbidity and mortality. Mechanisms of heart disease may be partly related to untreated chronic inflammation. Cardiovascular magnetic resonance imaging allows a comprehensive assessment of myocardial structure, function, and tissue characterization. We investigated, using cardiovascular magnetic resonance, subclinical inflammation and myocardial disease in asymptomatic HIV-infected individuals. METHODS AND RESULTS: Myocardial structure and function were assessed using cardiovascular magnetic resonance at 1.5-T in treated HIV-infected individuals without known cardiovascular disease (n=103; mean age, 45±10 years) compared with healthy controls (n=92; mean age, 44±10 years). Assessments included left ventricular volumes, ejection fraction, strain, regional systolic, diastolic function, native T1 mapping, edema, and gadolinium enhancement. Compared with controls, subjects with HIV infection had 6%
Aims To estimate the life attributable risk (LAR) of cancer incidence over a wide range of dose radiation exposure and a large spectrum of possible diagnostic computed tomographic coronary angiography (CTCA) scenarios.. Methods This study included 561 consecutive patients who underwent a successful prospective ECG-gating CTCA protocol (low-dose group) 64-slice CTCA and 188 patients who underwent retrospective ECG-gating CTCA with ECG-triggered dose modulation CTCA (high-dose group). LAR was computed, given the organ equivalent dose, for all cancers in both sexes. LAR was tabulated for each decile of dose-length product by 10-year age classes, separately for each sex.. Results Estimates of LAR of any cancer for an exposure at age ≤40 year were lower in males than in females for any given quantile. At age ≥50years, LAR was similar between sexes only at the lowest exposure doses, whereas at higher dosage, it was, in general, higher for women. At the median age of this case series (62 years) and ...
SCENARIA will change the general trend of CT.. In order to fully answer the needs of the patient, the operator and the doctor, image quality, workflow and user-friendliness have been refined. Hitachi aims for an all-round CT with absolutely no room for compromise. 64ch/128slice CT SCENARIA is reborn.. 0.35s/rot, which can be used for not only the heart but also for any regions of the whole body such as the abdomen and the lower extremities, and the CORE method, which reduces various artifacts at high-pitch scanning, these features achieve both high-speed scanning and high image quality.. High-speed view rate. In order to secure sufficient data density in the periphery area even for scanning of the maximum FOV size, not only the heart but also all regions can be scanned at 0.35s/rot. This is realized by high-speed view rate of max.2,880 views/s data collection system developed exclusively for SCENARIA.. ...
Sydney Adventist Hospital is a modern acute care facility with all diagnostic and therapeutic services. The San offers a wide range of specialties including cardiac care, maternity and more.
Learning Medical Imaging, Cardiac CT to Contrast guides, Unique modules, Quiz of the month, Imaging pearls, Journal Club, Medical Illustrations, CME Courses|CTisus
Learning Medical Imaging, Cardiac CT to Contrast guides, Unique modules, Quiz of the month, Imaging pearls, Journal Club, Medical Illustrations, CME Courses|CTisus
Steady-state free precession (SSFP) is a highly-efficient MRI pulse sequence that has been a fairly recent arrival in the functional MRI realm. Several methods for using balanced SSFP to detect the BOLD signal have been proposed to date and will be discussed in this review. After a brief introduction to the general properties of SSFP, this review describes the quite different approaches of transition-band and pass-band SSFP in terms of functional contrast mechanism. It then discusses the potential advantages of these techniques, followed by their challenges and shortcomings. Finally, it gives an overview of some applications considered to date and the authors perspective on where these techniques are headed. In the spirit of this special issue, the author also includes some of the personal history underlying her own explorations in this area. © 2011 Elsevier Inc.
TY - JOUR. T1 - Flow-weighted MRI of the lungs with the ECG-gated half-fourier FSE technique. T2 - Evaluation of the effect of the cardiac cycle. AU - Kawanami, Satoshi. AU - Nakamura, Katsumi. AU - Miyazaki, Mitsue. AU - Sugiura, Satoshi. AU - Yamamoto, Shuichiro. AU - Nakata, Hajime. PY - 2002/12/1. Y1 - 2002/12/1. N2 - We investigated temporal MR signal changes in the peripheral lung and proximal pulmonary vessels during the entire cardiac cycle in order to evaluate the characteristics of the diastolic-systolic subtraction method in the lung. In eight healthy volunteers free of lung diseases, changes in the MR signal during one breath-hold were investigated with the multiple ECG-triggered half-Fourier single-shot fast-spin echo (SS-FSE) technique. The signal intensity-time course curve in the lung showed that biphasic signals decreased 20% to 47% at systole and 5% to 33% at mid-diastole, measured against the maximum signals at late diastole. This signal decrease in the peripheral lung was ...
Cardiac CT - radiation doses, dose management and practical issues. L 11. Answer True or False. Patient dose from a cardiac CT is equivalent to 20 chest conventional radiographies. In cardiac CT the radiation dose to the different organs is very similar to the catheterization procedures....
The fetal electrocardiogram signal (FECG) is a major tool in monitoring and diagnosis of the fetus high risk conditions and arrhythmias. This paper introduces an accurate mathematical model for fetal electrocardiogram based on a real template FECG signal. This is done after elimination of maternal electrocardiogram (MECG) signal interference measured during pregnancy. The parameters of the introduced model are optimized in terms of sum square error using a genetic algorithm (GA). Our precise fetal electrocardiogram model can be a benchmark for other prospective researches particularly in FECG extraction. ©2007 IEEE.. ...
Our results are the first documentation of defense-like behaviors evoked by activation of DLSC in the non-human primate. Activation of DLSC by the focal blockade of GABAergic inhibition evoked cowering, escape-like responses, high-pitch vocalizations, and attack of objects. These findings were unexpected in the context of the theoretical perspective presented by Dean et al. (1989) that emphasized a preferential role of primate DLSC for approach responses rather than defensive responses. Our findings indicate that the function of DLSC as a substrate for responding to threats is conserved across species.. Activation of DLSC produced defense-like responses that were both passive (i.e., cowering) and active (i.e., escape-like behavior, attack of objects), as well as an increase in defensive vocalization. For a given animal, the behavioral responses evoked from different sites within DLSC were consistent across infusions, suggesting that the various defense-like behaviors do not have independent site ...
For busy laboratories that need to get the answer right the first time, with efficient workflows, SONAR offers new possibilities, with an acquisition mode that collects MS/MS results from a Data Independent Acquisition (DIA) experiment.
Learning Medical Imaging, Cardiac CT to Contrast guides, Unique modules, Quiz of the month, Imaging pearls, Journal Club, Medical Illustrations, CME Courses|CTisus
Learning Medical Imaging, Cardiac CT to Contrast guides, Unique modules, Quiz of the month, Imaging pearls, Journal Club, Medical Illustrations, CME Courses|CTisus
TY - JOUR. T1 - Three-dimensional evaluation of root dimensions and alveolar ridge width of maxillary lateral incisors in patients with unilateral agenesis. AU - AlRushaid, Sharifah. AU - Chandhoke, Taranpreet. AU - Utreja, Achint. AU - Tadinada, Aditya. AU - Allareddy, Veerasathpurush. AU - Uribe, Flavio. PY - 2016/12/1. Y1 - 2016/12/1. N2 - Background: The objective of this retrospective case-control study was to measure the maxillary lateral incisor root dimensions and quantify the labial and palatal bone in patients with unilateral maxillary lateral incisor agenesis (MLIA) after orthodontic treatment and compare them to non-agenesis controls using cone beam computed tomography. Methods: The labiopalatal and mesiodistal root dimensions, mesiodistal coronal dimensions, and labiopalatal bone and alveolar ridge widths of the maxillary lateral incisor were assessed on posttreatment cone beam computed tomography scans of 15 patients (mean age 16.5 ± 3.4 years, 9 females and 6 males) with ...
OBJECTIVE: To compare radiation doses delivered at prospectively ECG-triggered sequential- (SEQ), retrospectively ECG-gated spiral- (RETRO) and prospectively ECG-triggered high-pitch spiral- (HP) computed tomography coronary angiography (CTCA) protocols, as well as catheter coronary angiography (CCA) using an anthropomorphic phantom. MATERIALS AND METHODS: An anthropomorphic Alderson phantom equipped with 50 thermoluminescent dosimeters (TLDs) was scanned using different CTCA protocols and an uncomplicated diagnostic CCA examination was simulated. Absorbed doses were experimentally determined and effective doses calculated using the dose-length product (DLP) for CTCA and the dose-area product (DAP) for CCA, as well as according to International Commission on Radiation Protection (ICRP) publications 60 and 103. RESULTS: Effective organ doses were significantly lower for HP protocols (100kV: 0.17±0.26mSv; 120kV: 0.26±0.39mSv) compared to SEQ protocols (100kV: 0.50±0.79mSv; 120kV: 0.90±1.41mSv; ...
Purpose: 4D CT is routinely performed during radiation therapy treatment planning of thoracic and abdominal cancers. Compared with the cine mode, the helical mode is advantageous in temporal resolution. However, a low pitch (∼0.1) for 4D CT imaging is often required instead of the standard pitch (∼1) for static imaging, since standard image reconstruction based on analytic method requires the low-pitch scanning in order to satisfy the data sufficient condition when reconstructing each temporal frame individually. In comparison, the flexible iterative method enables the reconstruction of all temporal frames simultaneously, so that the image similarity among frames can be utilized to possibly perform high-pitch and sparse-view helical 4D CT imaging. The purpose of this work is to investigate such an exciting possibility for faster imaging with lower dose. Methods: A key for highpitch and sparse-view helical 4D CT imaging is the simultaneous reconstruction of all temporal frames using the prior ...
All patients were scanned with a 64-slice CT scanner (Sensation 64, Siemens) equipped with a new feature in multislice CT technology, so-called z-axis flying-focus technology.13 The central 32 detector rows acquire 0.6-mm slices, and the flying-focus spot switches back and forth between 2 z positions between each reading. Two slices per detector row are acquired, which results in a higher oversampling rate in the z axis, thereby reducing artifacts related to the spiral acquisition and improving spatial resolution down to 0.4 mm3.13 Angiographic scan parameters included the following: number of slices per rotation, 32×2; individual detector width, 0.6 mm; rotation time, 330 ms; table feed, 3.8 mm per rotation; tube voltage, 120 kV; tube current, 900 mA; and prospective x-ray tube modulation, none. Calcium scoring parameters (similar unless indicated) were a tube current of 150 mA and prospective x-ray tube modulation. The radiation exposure for CT coronary angiography with this scan protocol was ...
This paper focuses on validating a novel framework for estimating the functional strain from cine cardiac magnetic resonance imaging (CMRI). The framework consists of three processing steps. First, the left ventricle (LV) wall borders are segmented using a level-set based deformable model. Second, the points on the wall borders are tracked during the cardiac cycle based on solving the Laplace equation between the LV edges. Finally, the circumferential and radial strains are estimated at the inner, mid-wall, and outer borders of the LV wall. The proposed framework is validated using synthetic phantoms of the material strains that account for the physiological features and the LV response during the cardiac cycle. Experimental results on simulated phantom images confirm the accuracy and robustness of our method ...
Point matches between images within an image sequence are identified by sparse optical flow computation and employed to compute a fundamental matrix for the epipolar geometry, which in turn is employed to derive an epipolar geometry constraint for computing dense optical flow for the image sequence. The epipolar geometry constraint may further be combined with local, heuristic constraints or robust statistical methods. Improvements in both accuracy and performance in computing optical flow are achieved utilizing the epipolar geometry constraint.
... : The Corometrics Model 126 Fetal Monitor includes two ultrasound transducers, a toco probe, one pack of paper, and power cord. It is in excellent condition and certified to proper operating specifications.Warranty: 1 Year - Parts and Labor.The Model 126 improved upon and replaced the 110 and 150 series, such as the 150 (Twins) Fetal Monitor. It features standard fetal monitoring parameters, such as dual ultrasound, fetal ECG (FECG), and uterine activity with both Toco and IUP.ParameterUSUS2FECGTOCOIUPNBPMsPO2MECGModel 126xxxxxModel 128xxxxxxxModel 129xxxxxxxxFeaturesCorometrics Model 126 Fetal Monitor FeaturesDual ultrasonic heart rate monitoring allows for non-invasive monitoring of twins.A +20 BPM heart rate offset option is provided for the secondary heart rate (HR2) trend, when using dual ultrasound, or ultrasound and direct FECG, to separate overlapping FHR trends for easy interpretation.Heartbeat coincidence to ensure you are
Evidence-based recommendations on new generation cardiac CT scanners (Aquilion ONE, Brilliance iCT, Discovery CT750 HD and Somatom Definition Flash) for cardiac
Unwounded feelingsAs they were throbbing in Winded scenarioAs I saw and imagined you Sometimes imaginationBought satisfactionVery urge to be with you Presence absenceBeing far awayVirtual situations which only satisfies Not too far awaySilence resonance at times Heard and saidCry and laughWas the only solution Waiting to meet your eyesWanting to talk to all those unsharedNeeding to satisfy all your hears Days not…
Learning Medical Imaging, Cardiac CT to Contrast guides, Unique modules, Quiz of the month, Imaging pearls, Journal Club, Medical Illustrations, CME Courses|CTisus
Learning Medical Imaging, Cardiac CT to Contrast guides, Unique modules, Quiz of the month, Imaging pearls, Journal Club, Medical Illustrations, CME Courses|CTisus
Flexor Retinaculum Of The Foot Extensor Retinaculum Foot Extensor Retinaculum Foot Inferior Extensor Retinaculum Of Foot Wikipedia, Extensor Retinaculum Foot Ankle And Foot Clinical Gate, Extensor Retinaculum Foot Vessels Of The Leg Basicmedical Key, Flexor Retinaculum Of The Foot Extensor Retinaculum Foot, ...
Quantitative T1-mapping is rapidly becoming a clinical tool in cardiovascular magnetic resonance (CMR) to objectively distinguish normal from diseased myocardium. The usefulness of any quantitative technique to identify disease lies in its ability to detect significant differences from an established range of normal values. We aimed to assess the variability of myocardial T1 relaxation times in the normal human population estimated with recently proposed Shortened Modified Look-Locker Inversion recovery (ShMOLLI) T1 mapping technique. A large cohort of healthy volunteers (n = 342, 50% females, age 11-69 years) from 3 clinical centres across two countries underwent CMR at 1.5T. Each examination provided a single average myocardial ShMOLLI T1 estimate using manually drawn myocardial contours on typically 3 short axis slices (average 3.4 ± 1.4), taking care not to include any blood pool in the myocardial contours. We established the normal reference range of myocardial and blood T1 values, and assessed
Eleven swine were studied, 3 of which were studied to define the optimal timing, volume, and duty cycle of balloon inflation. Eight swine were studied with two defined protocols at baseline and with ICP gradually raised to a mean of 30.5 mm Hg. ICBP activation caused a consistent modification of the ICP waveform. Two ICBP activation protocols were used. Balloon activation protocol A led to a consistent elevation in cerebral blood flow (8%-25% above baseline, p , 0.00001). Protocol B resulted in a modest reduction of ICP over time (8%-11%, p , 0.0001) at all ICP levels. Neither protocol significantly affected systemic physiological parameters. ...
All information about the latest scientific publications of the Clínica Universidad de Navarra. Quantification of left ventricular function and mass in cardiac Dual-Source CT (DSCT) exams: comparison of manual and semiautomatic segmentation algorithms
I prefer not to take this approach, and I believe I have good reasons to do so from a timeliness(speed of computations) as well as a stability and accuracy perspective. A test that you could easily do is to do a forward estimation flow (Uf), then a backward one (Ub), and take the average as your final estimate (minus sign on the backward first):. Ufinal = (Uf - Ub)/2. This could be compared to the output you get from using grad3D.m as it is now.. Using the grad3D.m version I have provided I BELIEVE will give better end result with less computations, but this is not something thoroughly tested. Some of the reasoning behind this is found in the tutorial text. In short, you can consider the video as a volume, and both the forward and the backward schemes then correspond to mis-aligned kernels/stencils. This has practical implications for how well the optical flow constraint equation will hold, and thus how good any optical flow can be calculated ...
The results of this study should be interpreted in the context of the study design and consequent limitations. First, although a study group of 170 patients was reasonable for this initial study, further re-evaluation of our findings with low-tube-voltage acquisitions in larger patient cohorts is necessary. Second, there may be differences regarding the average radiation exposure of neck DECT among various dual-source CT systems. We also expect differences between single- or dual-source 80-kVp CT, and our results from retrospective analysis of the 80-kVp images from DECT should be evaluated in additional studies with phantom measurements. Especially single-source 80-kVp CT may also show a different image quality because the 140-kVp tube in DECT may have an effect on the 80-kVp DECT images. However, 80-kVp neck CT can still be expected to result in a distinct dose reduction.16 DECT may result in a slower scan speed than certain single- or dual-source CT systems, which may lead to more motion ...
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RiTradiology.com ดูแลรักษาโดยและเป็นของ น.พ.รัฐชัย แก้วลาย. โลโก้ RiTradiology.com เป็นลิขสิทธิ์ของ น.พ.รัฐชัย แก้วลาย. ข้อมูลส่วนตัวของคุณถือเป็นความลับและจะไม่ถูกเผยแพร่ไปยังบุคคลที่สาม. ข้อมูลใน RiTradiology.com ใช้เป็นแนวทาง, ไม่ใช่เพื่อทดแทน, การให้การวินิจฉัย, รักษาและคำแนะนำสำหรับผู้ป่วย. แพทย์ของคุณอาจให้คำแนะนำในการวินิจฉัยหรือรักษาเป็นอย่างอื่นขึ้นกับข้อมูลและสถานการณ์นั้นๆ. ...
Think about how often you see rocks every day. Have you ever imagined that one could be alive? Unless you are in Chile or Peru, this probably isnt the case. But then again, after reading about this creature, you may believe anything is possible.
Nemours expert pediatric ophthalmologists are experienced in diagnosing and performing pediatric cataract surgery on infants and children of all ages.
basis of record Boxshall, G. (2001). Copepoda (excl. Harpacticoida), in: Costello, M.J. et al. (Ed.) (2001). European register of marine species: a check-list of the marine species in Europe and a bibliography of guides to their identification. Collection Patrimoines Naturels, 50: pp. 252-268 (look up in IMIS) [details] ...
Detailed knowledge of aortic root geometry is a prerequisite to anticipate complications of transcatheter aortic valve (TAV) implantation. We determined coronary ostial locations and aortic root dimensions in patients with aortic stenosis (AS) and compared these values with normal subjects using computed tomography (CT). One hundred consecutive patients with severe tricuspid AS and 100 consecutive patients without valvular pathology (referred to as the controls) undergoing cardiac dual-source CT were included. Distances from the aortic annulus (AA) to the left coronary ostium (LCO), right coronary ostium (RCO), the height of the left coronary sinus (HLS), right coronary sinus (HRS), and aortic root dimensions [diameters of AA, sinus of Valsalva (SV), and sino-tubular junction(STJ)] were measured. LCO and RCO were 14.9 ± 3.2 mm (8.2-25.9) and 16.8 ± 3.6 mm (12.0-25.7) in the controls, 15.5 ± 2.9 mm (8.8-24.3) and 17.3 ± 3.6 mm (7.3-26.0) in patients with AS. Controls and patients with AS had ...
Detailed nutritional values of Turkey wing, from whole bird, non-enhanced, only meat, raw natural. Online analysis information with non-nutrients and nutrients composition facts table for item No. 05227 found in category Poultry Products. Data contents chart for nutritionists. Food details for TURKEY,WING,FROM WHL BIRD,NON-ENHANCED,MEAT ONLY,RAW in different kinds of quantities, amounts or measurements.
BRIEF HISTORICAL SUMMARY : In 1853 an Appenzell Cattle Dog was first described in the book "Tierleben der Alpenwelt" (Animal Life in the Alps) as a "high-pitch barking, short-haired, medium size, multicolour cattle dog of a quite even Spitz type, which can be found in certain regions and is used partly to guard the homestead, partly to herd cattle." In 1895, the great promotor of the breed, head-forester Max Siber, asked the SKG (Schweizerische Kynologische Gesellschaft, Swiss Cynological Society) to do something for the breed. 1898 the executive authorities of the Canton St. Gallen put the sum of SFr. 400.- at disposal to support the breeding of the Appenzell Cattle Dog. The SKG then formed a special commission, the characteristic traits of the breed were fixed, and at the fair at Altstätten 9 dogs and 7 bitches appeared; they received prizes between SFr.5. to 10-. As a result, 8 Appenzell Cattle Dogs were shown at the first international dog show in Winterthur and entered in the newly ...
A 4D PET imaging reconstruction technique may help improve image quality and reduce noise during cardiac-gated PET scans, according to research presented June 10 at the 59th annual meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI) in Miami.
Many low level visual computation problems such as focus, stereo, optical flow, etc., can be formulated as problems of extracting one or more parameters of a non-stationary transformation between two
Until recently, a radiologist primarily used cardiac CT to visualize coronary arteries. How have recent technology developments broadened the scope of CTA? The evolution of CT from 64-MDCT through dual-source scanners has provided the impetus to a rethinking of the role of CT in many clinical scenarios. Many of these scenarios are some of imagings most challenging clinical dilemmas and involve vascular structures of the chest ranging from the great vessels off the arch to the individual cardiac chambers and the pericardium. In many cases, the diagnoses are difficult and differential diagnosis is a critical first step. In addition, many pathologies are somewhat similar in appearance on CT scans. The differential diagnosis is broad, but specific CT findings may be helpful. The radiologist must be aware of the range of these pathologies when a chest or cardiac CT scan is ordered.. What types of extracoronary findings are possible with CTA? Findings range from tumors or thrombi in the cardiac ...
The freeMD virtual doctor has found 85 conditions that can cause Feel Faint and Unsteady Heartbeat. There are 7 common conditions that can cause Feel Faint and Unsteady Heartbeat. There are 21 somewhat common conditions that can cause Feel Faint and Unsteady Heartbeat. There are 25 uncommon conditions that can cause Feel Faint and Unsteady Heartbeat. There are 32 rare conditions that can cause Feel Faint and Unsteady Heartbeat.
We develop computational models that formalize the principles of perception and enable computers to understand the visual world of surfaces, materials, light and movement.
Study Flashcards On Cardiac Cycle at Cram.com. Quickly memorize the terms, phrases and much more. Cram.com makes it easy to get the grade you want!
Number one ratings attraction on Fox News, Bill OReilly, recently cooed that in his opinion, "Barack Hussein Obama is a patriot". That should tell you the reliability of the content on his OReilly Factor program. Muslim Prince Alwaleed owns the largest chunk of News Corp. stock outside the Murdoch family. Shortly after his purchase of 5.5 percent of News Corp. voting shares in 2005, Alwaleed gave a speech that made it clear just what he had bought. As noted in The (U.K.) Guardian, Alwaleed told an audience in Dubai that it took just one phone call to Rupert Murdoch - "speaking not as a shareholder but as a viewer," Alwaleed said - to get the Fox News crawl reporting "Muslim riots" in France changed to "civil riots." ...
BACKGROUND: The latest gamma-camera generation with cadmium-zinc-telluride (CZT) detectors allows myocardial perfusion imaging (MPI) with respiratory triggering at breath-hold. We assessed its impact on functional left ventricular (LV) parameters. METHODS: Twenty-eight consecutive patients underwent a one-day (99m)Tc-tetrofosmin pharmacologic stress/rest imaging protocol on a novel CZT camera. Electrocardiogram-gated high-dose (rest) MPI was performed without and with real-time respiratory triggering by intermittent scanning confined to breath-hold at deep inspiration. We studied the effect of respiratory triggering at deep inspiration levels on LV wall motion, wall thickening, LV volumes and ejection fraction (LVEF) compared to regular MPI without respiratory triggering. RESULTS: Compared to regular MPI without respiratory triggering, systolic and diastolic LV volumes and stroke volumes decreased significantly (P , 0.05) when respiratory triggering was applied. By contrast, there was no ...
Poster: ECR 2019 / C-1843 / Non-enhanced MRI DWIBS in assessment of liver metastasis in breast cancer patients by: M. M. A. Rezk1, M. T. El-Diasty2, A. Nazeer1, Y. S. Habib1, T. Raafat1, M. Abu el dahab1; 1Cairo/EG, 2Jeddah/SA
Poster: ECR 2019 / C-1843 / Non-enhanced MRI DWIBS in assessment of liver metastasis in breast cancer patients by: M. M. A. Rezk1, M. T. El-Diasty2, A. Nazeer1, Y. S. Habib1, T. Raafat1, M. Abu el dahab1; 1Cairo/EG, 2Jeddah/SA
As the waves from the earthquake moved through the earth, they also triggered new earthquakes thousands of miles away. In this example, taken from measurements in California, the quake created subtle movements deep in the San Andreas Fault. The initial noise, which sounds like distant thunder, corresponds with the Japanese mainshock. Afterwards, a continuous high-pitch sound, similar to rainfall that turns on and off, represents induced tremor activity at the fault. This animation not only help scientists explain the concept of distant triggering to general audiences, but also provides a useful tool for researchers to better identify and understand such seismic signals in other regions. The human ear is able to hear sounds for frequencies between 20 Hz and 20 kHz, a range on the high end for earthquake signals recorded by seismometers. Peng, graduate student Chastity Aiken and other collaborators in the U.S. and Japan simply played the data faster than true speed to increase the frequency to ...
The objective of this study was to analyze ST segment analyses (STAN) using simultaneous traditional - gold standard invasive (fetal scalp electrode) and newly available non-invasive abdominal fetal electrocardiography (fECG) during delivery.This was
Objectives: This study aimed to measure the absorbed doses in selected organs for prospectively ECG-triggered coronary computed tomography angiography (CCTA) using five different generations CT scanners in a female adult anthropomorphic phantom and to estimate the effective dose (HE). Materials and Methods: Prospectively ECG-triggered CCTA was performed using five commercially available CT scanners: 64-detector-row single source CT (SSCT), 2 × 32-detector-row-dual source CT (DSCT), 2 × 64-detector-row DSCT and 320-detector-row SSCT scanners. Absorbed doses were measured in 34 organs using pre-calibrated optically stimulated luminescence dosimeters (OSLDs) placed inside a standard female adult anthropomorphic phantom. HE was calculated from the measured organ doses and compared to the HE derived from the air kerma-length product (PKL) using the conversion coefficient of 0.014 mSv_mGy-1_cm-1 for the chest region. Results: Both breasts and lungs received the highest radiation dose during CCTA ...
PURPOSE: To compare cardiac cine MR imaging using steady state free precession (SSFP) and fast low angle shot (FLASH) techniques at 1.5 and 3 T, and to establish their variabilities and reproducibilities for cardiac volume and mass determination in volunteers. To assess the feasibility of SSFP imaging in patients at 3 T and to determine comparability to volume data acquired at 1.5 T. MATERIALS AND METHODS: Ten healthy volunteers underwent cardiac magnetic resonance imaging using SSFP and segmented gradient-echo FLASH, using both a 1.5 and a 3 T MR system on the same day. Ten patients with impaired left ventricular (LV) function were also studied at both field strengths with SSFP. RESULTS: For both SSFP and FLASH, field strength had no effect on the quantification of LV and right ventricular (RV) volumes, mass, or function (P | or = 0.05 for field strength for all parameters). At both 1.5 and 3 T, SSFP yielded smaller LV mass (e.g., at 3 T 109 +/- 30 g vs. 142 +/- 37 g; P = 0.011) and larger LV volume (e
The global prosthetic heart valves market is expected to reach $1.4 bn by 2028, growing at a Compound Annual Growth Rate (CAGR) of 2.5 per cent, according to GlobalData, a leading data and analytics company.
now, today well be talking about the cardiac cycle. and the cardiac cycle well be discussing in two fashions, and one way we will discussing cardiac cycle while I will be doing different diagrams and in second phase, Well discuss the cardiac cycle Uhhhhh, When I will be presenting the errands during the cardiac cycle Graphically So first of all, ...
HEARTBEAT AFTER HEARTBEAT (BLACK EAGLE) LY TONG HEARTBEAT AFTER HEARTBEAT is about Ly Tong, who hitchhiked, took trains and buses, pedaled, walked and swam his way to freedom. A South Vietnamese pilot who was shot down just before the war ended, Ly Tong spent five years in
Typically, a fetal heartbeat is detected by an ultrasound during the seventh week of pregnancy, according to the American Pregnancy Association. Detecting a heartbeat at this point is a positive sign...
Learning Medical Imaging, Cardiac CT to Contrast guides, Unique modules, Quiz of the month, Imaging pearls, Journal Club, Medical Illustrations, CME Courses|CTisus
Learning Medical Imaging, Cardiac CT to Contrast guides, Unique modules, Quiz of the month, Imaging pearls, Journal Club, Medical Illustrations, CME Courses|CTisus
Georgia has just added itself to the list of states that aim to protect unborn life once a fetal heartbeat is detected. The Georgia House of Representatives March 29 passed H.B. 481, entitled the Li...
Imagine cyclists riding up a hill, its pretty steep if they stop or slow down too much they will be overtaken by the race officials and ejected from the race. Some cyclists are further in front of the officials than others, they have a greater physiological reserve. Some are more persuasive at being able to…
Im six weeks 1 day pregnant today, this is my first so Im new to all of this. I went in for my first ultrasound today but the doc was unable to...
... solved by using cardiac ECG gating, faster scan techniques and breath hold imaging. Increasingly sophisticated techniques were ... but the image quality is limited. Instead most sequences use ECG gating to acquire images at each stage of the cardiac cycle ... Cardiac stress test Bruce protocol. Electrophysiology study. Cardiac imaging. Angiocardiography. Echocardiography TTE. TEE. ... Cardiac magnetic resonance imaging. An example of CMR movies in different orientations of a cardiac tumor - in this case, an ...
... will usually involve a gating technique, such as breathing tracking, so that image acquisition is automatically triggered ... the cardiac cycle and parathyroid washout of contrast. Downsides of 4DCT for diagnostic purposes include large and complex ... Recognition Techniques and Applications in Medical Imaging. Springer. p. 63. ISBN 9783642184215. Jr, Brendan C. Stack; Bodenner ... This gating can also be applied at treatment, where the radiotherapy beam is only switched on at certain points in the ...
2nd Edition February 2006 Medical Imaging systems technology, Cornelius T. Leondez, published 2005 Cardiac gating technique for ... The Fourier transform of the masked image is taken. The phase of the original image is changed to the model image (the image ... Chun Yuan Cardiac gating technique for arterial oxygen saturation measurement Rasoul Yousefi; Mehrdad Nourani 2014 IEEE ... Advantage Faster than Cardiac gating and doesn't require too much co-operation from the patient. Disadvantage The choice of the ...
... retrospective cardiac gating and respiratory compensation are employed. Beginning with cardiac gating, the patient's ECG signal ... Phase contrast MRI is one of the main techniques for magnetic resonance angiography (MRA). This is used to generate images of ... This means that these scans are cardiac-averaged so the measured blood velocities are an average over multiple cardiac cycles. ... Phase contrast magnetic resonance imaging (PC-MRI) is a specific type of magnetic resonance imaging used primarily to determine ...
Cardiac gated acquisitions are possible with SPECT, just as with planar imaging techniques such as multi gated acquisition scan ... such as functional cardiac or brain imaging. Myocardial perfusion imaging (MPI) is a form of functional cardiac imaging, used ... tumor imaging, infection (leukocyte) imaging, thyroid imaging or bone scintigraphy. Because SPECT permits accurate localisation ... In the nuclear power sector, the SPECT technique can be applied to image radioisotope distributions in irradiated nuclear fuels ...
... gated blood-pool imaging MeSH E01.370.370.050.650.650.950 --- ventriculography, first-pass MeSH E01.370.370.065 --- angioscopy ... electrophysiologic techniques, cardiac MeSH E01.370.370.380.250 --- exercise test MeSH E01.370.370.380.400 --- heart ... gated blood-pool imaging MeSH E01.370.370.380.710.950 --- ventriculography, first-pass MeSH E01.370.370.380.950 --- valsalva ... gated blood-pool imaging MeSH E01.370.350.710.715.710.950 --- ventriculography, first-pass MeSH E01.370.350.710.800 --- ...
One of the 2020 systems was operate at Brigham and Women's Hospital attempting cardiac gated imaging. Also in the product line ... "Image Reconstruction from Projections," page 56). In that technique a series of X-ray exposures made from different angles ... A digital image was acquired without contrast and one with, and the images subtracted from each other leaving the arterial ... One of the units at the Cleveland Clinic was used to construct an image of the body that today would be called a "Scout View", ...
Certain techniques such as fMRI image tissues (particularly cerebral tissues) by blood flow and thus show metabolism. Also, ... a cardiac gated time sequence, or a spatial sequence where the gamma-camera is moved relative to the patient. SPECT (single ... The end result of the nuclear medicine imaging process is a "dataset" comprising one or more images. In multi-image datasets ... The fusion imaging technique in nuclear medicine provides information about the anatomy and function, which would otherwise be ...
... gate' the acquisition. The final result is a series of images of the heart (usually sixteen), one at each stage of the cardiac ... The in vivo technique is more convenient for the majority of patients since it is less time-consuming and less costly and more ... or gated blood pool imaging, as well as SYMA scanning (synchronized multigated acquisition scanning). This mode of imaging ... A MUGA scan (multigated acquisition) involves an acquisition triggered (gated) at different points of the cardiac cycle. MUGA ...
Cardiac gated acquisitions are possible with SPECT, just as with planar imaging techniques such as multi gated acquisition scan ... Main article: Myocardial perfusion imaging. Myocardial perfusion imaging (MPI) is a form of functional cardiac imaging, used ... such as functional cardiac or brain imaging. Myocardial perfusion imagingEdit. This section needs additional citations for ... Single-photon emission computed tomography (SPECT, or less commonly, SPET) is a nuclear medicine tomographic imaging technique ...
... size from rodents to human biopsies Lung imaging using respiratory gating Cardiovascular imaging using cardiac gating Imaging ... 3D imaging techniques in characterization of larval migration through the CNS of vertebrates". Micron (Oxford, England: 1993). ... "Advanced Non-Destructive Ocular Visualization Methods by Improved X-Ray Imaging Techniques". PLoS ONE. 12 (1). doi:10.1371/ ... creating projection images that later will be used to reconstruct the image cross-sections. In an open system, X-rays may ...
Applying a Level Set Method for Resolving Physiologic Motions in Free-Breathing and Non-gated Cardiac MRI. FIMH, 2013, [7] S ... Rapid NMR imaging of dynamic processes using the FLASH technique. Magn Reson Med 3:321-327 [3] doi:10.1002/mrm.1910030217 S ... Zhang S, Olthoff A and Frahm J. Real-time magnetic resonance imaging of normal swallowing. J Magn Reson Imaging 2011;35:1372- ... so that high-quality images may be obtained out of as little as 5 to 10% of the data required for a normal image reconstruction ...
"Ionizing radiation in cardiac imaging: a science advisory from the American Heart Association Committee on Cardiac Imaging of ... image reconstruction. In this technique, a portion of the heart is imaged during one heart cycle while an ECG trace is recorded ... The latest MSCT scanners acquire images only at 70-80% of the R-R interval (late diastole). This prospective gating can reduce ... allowing excellent imaging of the coronary arteries (cardiac CT angiography). Images with even higher temporal resolution can ...
Thus, it took the participant longer to walk mentally through a narrow gate than to walk through a larger gate placed at the ... Mental practice is a technique used in music as well. Professional musicians may use mental practice when they are away from ... Measurements of cardiac and respiratory activity during motor imagery and during actual motor performance revealed a ... These methods have revealed that motor images retain many of the properties, in terms of temporal regularities, programming ...
... refers to iterative algorithms used to reconstruct 2D and 3D images in certain imaging techniques. For ... Applying a Level Set Method for Resolving Physiologic Motions in Free-Breathing and Non-gated Cardiac MRI. FIMH, 2013, (PDF) ... Here is an example that illustrates the benefits of iterative image reconstruction for cardiac MRI. Tomographic reconstruction ... In Magnetic Resonance Imaging it can be used to reconstruct images from data acquired with multiple receive coils and with ...
Different advanced techniques, including finite elements algorithms, are being designed to fulfill the computational ... Generally, the field has focused on topics, such as image processing, the electronic patient record, equipment development, the ... Cardiac Output Monitoring and Diagnostic Unit) which improved artificial heart flux measurement. This device was then used ... and Field Programmable Gate Array (FPGA, Altera MAX+PLUS). Signal communication USB, RS232 and digital filters implementation ...
Use of any one of these imaging modalities enables the physician to view the placement of the needle. Electrical stimulation ... The lumbar plexus block is an advanced technique indicated for hip, anterior thigh, and knee surgery. The lumbar plexus is ... Lidocaine preferentially binds to the inactivated state of voltage gated sodium channels, but has also been found to bind ... Additionally, this may lead to seizures, arrhythmias, and may progress to cardiac arrest. This reaction may stem from an ...
C-mode: A C-mode image is formed in a plane normal to a B-mode image. A gate that selects data from a specific depth from an A- ... Medical ultrasound (also known as diagnostic sonography or ultrasonography) is a diagnostic imaging technique based on the ... Page 161 (part II > Two-dimensional Echocardiography) in: Reves, J. G.; Estafanous, Fawzy G.; Barash, Paul G. (2001). Cardiac ... Color Doppler images are generally combined with grayscale (B-mode) images to display duplex ultrasonography images. Uses ...
What's New in Cardiac Imaging?: SPECT, PET, and MRI Springer, 1992, p. 41. ... Patel, C. K. N.; Bennett Jr., W. R.; Faust, W. L.; McFarlane, R. A. Infrared spectroscopy using stimulated emission techniques ... Yamakura, T.; Harris, R. A. Effects of gaseous anesthetics nitrous oxide and xenon on ligand-gated ion channels. Comparison ... The Encyclopaedia of Medical Imaging. Taylor & Francis, 1998, p. 194. *↑ Warren, W. W.; Norberg, R. E. Nuclear Quadrupole ...
Gibb's work started with X-ray images, not CT or MRI images, for the reconstruction of a human phantom which was used for ... which is used to simulate cardiac and respiratory motions with more realistic modeling of the cardiac system. A polygonal mesh ... The proposed technique used to create the race-specific statistical phantom maintains anatomic realism and provides the ... at Rensselaer Polytechnic Institute used the 3D VIP-Man phantom to simulate respiratory motions by adopting the gated ...
The source locations can be combined with magnetic resonance imaging (MRI) images to create magnetic source images (MSI). The ... Another common technique is beamforming, wherein a theoretical model of the magnetic field produced by a given current dipole ... It is primarily used to remove artifacts such as blinking, eye muscle movement, facial muscle artifacts, cardiac artifacts, etc ... There has been great success isolating unique responses in patients with schizophrenia, such as auditory gating deficits to ...
This scan is done in conjunction with a cardiac stress test. Planar techniques, such as conventional scintigraphy, are rarely ... Shaw, L (April 2004). "Prognostic value of gated myocardial perfusion SPECT". Journal of Nuclear Cardiology. 11 (2): 171-185. ... DePuey, E. Gordon; Garcia, Ernest V.; Berman, Daniel Sholom (2001). Cardiac SPECT Imaging. Lippincott Williams & Wilkins. p. ... In keeping with the concept of comparison images, the second "stress" image was taken 4 hours after "stress" and compared with ...
This last technique has allowed for multiple modified optogenetic actuators to be used without the need to create a whole line ... Kerr, R.; Lev-Ram, V.; Baird, G.; Vincent, P.; Tsien, R. Y.; Schafer, W. R. (2000-06-01). "Optical imaging of calcium ... An issue with channelrhodopsin-2 is that its gating properties don't mimic in vivo cation channels of cortical neurons. A ... In addition, this approach has been applied in cardiac resynchronization therapy (CRT) as a new biological pacemaker as a ...
C-mode: A C-mode image is formed in a plane normal to a B-mode image. A gate that selects data from a specific depth from an A- ... is a diagnostic imaging technique based on the application of ultrasound. It is used to create an image of internal body ... Reves, J. G.; Estafanous, Fawzy G.; Barash, Paul G. (2001). Cardiac anesthesia: principles and clinical practice. Hagerstwon, ... Color Doppler images are generally combined with grayscale (B-mode) images to display duplex ultrasonography images. Uses ...
Several techniques such as intracellular recording, patch-clamp, and voltage-clamp technique, pharmacology, confocal imaging, ... As the rising phase reaches its peak, voltage-gated Na+ channels are inactivated whereas voltage-gated K+ channels are ... Moreover, the distinctions based on function between neurons and other cells such as cardiac and muscle cells are not helpful. ... The undershoot phase occurs because unlike voltage-gated sodium channels, voltage-gated potassium channels inactivate much more ...
The technique allows insight on the nature of how a protein's structure and conformational changes create/form protein function ... Watt W. Webb - developer of multiphoton microscopy Gregorio Weber - John Wikswo - research on biomagnetism and cardiac ... Roderick MacKinnon - determined first three-dimensional structure of voltage-gated transmembrane ion channel David H. MacLennan ... and non-image visual systems and in olfaction Ada Yonath (Israeli, 1939- ) winner of the 2009 Nobel Prize in Chemistry (with ...
Benzodiazepines are positive allosteric modulators of the GABA type A receptors (GABAA). The GABAA receptors are ligand-gated ... Elderly and very ill patients can possibly suffer apnea or cardiac arrest. Concomitant use of other central nervous system ... but confirmation and quantitation are usually performed using chromatographic techniques.[97][98][99] ... Riss J, Cloyd J, Gates J, Collins S (August 2008). "Benzodiazepines in epilepsy: pharmacology and pharmacokinetics". Acta ...
"3D VR Image Rendered by Google Cardboard Sets A Milestone in the History of Cardiac Surgery". Doximity. Retrieved 2016-05-24.. ... a new operative technique". Journal of Cardiac Surgery. 8 (5): 537-40. doi:10.1111/j.1540-8191.1993.tb00409.x. PMID 8219533.. ... "Research Gate. Retrieved 23 December 2014.. *^ Burke, Redmond (March 1995). "Video-Assisted Thoracoscopic Vascular Ring ... "MCH Cardiac Program Real Time Outcomes in Congenital Heart Surgery". www.pediatricheartsurgery.com. Retrieved 18 December 2014. ...
Expression of cardiac NOS2 has been associated with myocardial dysfunction. Therefore, we evaluated chagasic cardiomyopathy in ... To evaluate the role of gated cardiac magnetic imaging resonance (MRI) in Chagas' disease, we infected mice with ... Techniques for Hemagglutination and Hemagglutination-Inhibition with Arthropod-Borne Viruses D. H. Clarke and J. Casals ... f Application of cardiac gated magnetic resonance imaging in murine Chagas' disease. * L A Jelicks, J Shirani, M Wittner, ...
computer assisted image processing. Magnetic resonance imaging (MRI) is a truly non-invasive technique which is not associated ... MRI of the coronary arteries is, however, a challenging task owing to motion of the vessels during cardiac contraction and ... Vital Images Inc, Minneapolis, Minnesota, USA). In the volume rendering technique, all image pixels are integrated to project a ... Respiratory gated MRCA is a technique with an uncomplicated setup that can be performed in a clinical setting. At this stage of ...
... using phase analysis of gated single photon emission co ... Electrophysiologic Techniques, Cardiac / methods. Female. ... Accessory Atrioventricular Bundle / complications, pathology, radionuclide imaging*. Adult. Cardiac-Gated Single-Photon ... LV dyssynchrony as assessed by phase analysis of gated SPECT myocardial perfusion imaging in patients with Wolff-Parkinson- ... myocardial perfusion imaging (MPI).. METHODS: Forty-five WPW patients were enrolled and had gated SPECT MPI pre- and 2-3 days ...
... and power and frequency mapping with cardiac-gated and/or asynchronous magnetic resonance (MR) phase contrast (PC) techniques ... To characterize cardiac- and respiratory-driven cerebrospinal fluid (CSF) motions in intracranial space noninvasively, four- ... Cardiac-gated and asynchronous PC techniques. The cardiac-gated PC technique is the combination of continuous PC acquisition ... CSF motion visualization based on cardiac-gated PC imaging. Cardiac-gated PC velocity measurement was performed in three ...
... anatomical CT and MR images were used to delineate the gross tumour volumes (GTVs) for radiotherapy treatment planning. The ... List mode-driven cardiac and respiratory gating in PET. J Nucl Med 2009;50:674-81.PubMedCrossRefGoogle Scholar ... Boudraa A, Zaidi H. Image segmentation techniques in nuclear medicine imaging. In: Zaidi H, editor. Quantitative analysis of ... Image segmentation using deformable models. In: Sonka M, Fitzpatrick JM, editors. Handbook of medical imaging: medical image ...
Objective This study evaluated the respiratory motion of lungs using a nonlinear motion correction technique for respiratory- ... gated single photon emission computed tomography (SPECT) images. ... Development of a new dynamic NURBS-based cardiac-torso (NCAT) ... K 2006Lung motion correction on respiratory gated 3-D PET/CT imagesIEEE Trans Med Imaging2547685PubMedCrossRefGoogle Scholar ... K 2006Nonlinear motion correction of respiratory-gated lung SPECT imagesIEEE Trans Med Imaging2548695PubMedCrossRefGoogle ...
A number of techniques can be used to minimize dose from cardiac CT. For calcium scoring, prospective gating is recommended. ... Thus, physicians ordering and performing cardiac imaging should be very familiar with the dosage of radiation from cardiac ... Several studies have estimated E of cardiac CT (Table 7).33-53 Mean E for calcium scoring using retrospective gating ranges ... 56 Another possibility for lowering the dose in cardiac CT is the employment of prospective gating to only acquire images ...
What are the contraindications for the alternative imaging techniques? * Ultrasound * Gated CT ... Preliminary Diagnosis: Cardiac tumors. I. What imaging technique is first-line for this diagnosis?. Cardiac MRI with ... I. What imaging technique is first-line for this diagnosis? * II. Describe the advantages and disadvantages of this technique ... What alternative imaging techniques are available? * V. Describe the advantages and disadvantages of the alternative techniques ...
A cardiac gated-pulse x-ray tube could be used to decrease patient dose if diastolic imaging is sufficient. Imaging of the ... Current developments will make this technique more robust. Increasing the number of detector rows will result in improved ... These first results of ECG-gated multislice CT cardiac imaging are encouraging. At present, the quality of these scans is ... Multislice CT allows for rapid cardiac imaging during a single breath-hold. A multislice scanner operated in helical mode ...
... solved by using cardiac ECG gating, faster scan techniques and breath hold imaging. Increasingly sophisticated techniques were ... but the image quality is limited. Instead most sequences use ECG gating to acquire images at each stage of the cardiac cycle ... Cardiac stress test Bruce protocol. Electrophysiology study. Cardiac imaging. Angiocardiography. Echocardiography TTE. TEE. ... Cardiac magnetic resonance imaging. An example of CMR movies in different orientations of a cardiac tumor - in this case, an ...
... chemical shift imaging, diffusion imaging, functional MRI. Flow imaging, MR angiography, cardiac gated imaging. Hardware for ... Artefacts in diagnostic images. Biological effects of ultrasound. Safety regulations. Quality assurance. New techniques, ... X-rays as a diagnostic imaging tool. X-ray equipment design and use; image formation and factors affecting it. Radiation doses ... Topics covered include image formation, representation and display; image degradation and restoration; intensity and colour ...
Similarly, poor gating can result in slice misregistration artifact. This artifact can be minimized through image ... Current efforts to use hybrid-imaging techniques, such as single-photon emission CT (SPECT)/CT and positron emission tomography ... 45 One advantage of using cardiac CTA over stress imaging in the emergency department is that cardiac CTA can exclude ... 64 Additionally, several imaging societies have collaborated on the 2006 Appropriateness Criteria for Cardiac CT Imaging. 65 ...
Cardiac evaluation requires either ECG gated MRI or cine MRI.. Ischemic Heart Disease. At the present time MRI has limited ... Magnetic resonance imaging (MRI) is a new and innovative technique that affords anatomic images in multiple planes and may ... peripheral gating, chemical shift imaging, and fast scanning (gradient refocused images), may resolve many of these problems. ... Gated MRI is capable of defining many malformations of the cardiac chambers and the great vessels, such as transposition and ...
A certain number of phases are acquired for each cardiac cycle. This technique is called prospective gating with retrospective ... In order to minimize motion artifacts, cardiac gating is performed to synchronize image acquisition with cardiac motion. The ... Compared to the image acquired by retrospective reconstruction, the prospectively reconstructed image demonstrates no image ... Background: Obtaining cardiac images using MRI is challenging due to the perpetual motion of the heart. ...
... is a noninvasive method to image the coronary arteries. Applications include the following: Diagnosis of coronary artery ... Prospectively gated transverse coronary CT angiography versus retrospectively gated helical technique: improved image quality ... This technique requires retrospective gating and a regular heart rate. [4] For data from several cardiac cycles to be used for ... This technique requires retrospective gating and a regular heart rate. [39] For data from several cardiac cycles to be used for ...
This method combines previously used EKG gating techniques for cardiac blood pool visualization with new computerized ... Subsequently these images are processed on-line with a digital filter to increase definition of the cardiac borders. The eight ... Acquisition, processing and display of gated cardiac scintigrams Description: An improved method for non-traumatic and ... Non-linear image processing Description: Processing of nuclear medicine images is generally performed by essentially linear ...
... is the sole imaging modality with the ability, in 3 dimensions, to assess cardiac morphology, ventricular ... ... 1 CMR uses the same principles as other MR techniques with the addition of ECG gating in order to suspend cardiac motion. ... Cardiac magnetic resonance imaging (CMR) is the sole imaging modality with the ability, in 3 dimensions, to assess cardiac ... Cardiac MR techniques using SSFP imaging show promise in the evaluation of mechanical dyssynchrony.65 The improved spatial ...
The presence of air in the lungs makes magnetic resonance imaging (MRI) particularly challenging; hence, the development and ... Imaging using PASL techniques requires the use of breath-holding and cardiac gating. 6 ... Perfusion imaging There are 2 major techniques for MR perfusion imaging: First-pass contrast agent techniques and arterial spin ... MRI techniques for pulmonary imaging include perfusion imaging, with and without contrast agents; structural vascular imaging ...
Procedures to aid stroke assessment are available as are cardiac imaging including calcium scoring and ECG gated cardiac ... We also carry out other techniques such as virtual colonoscopy, angiography for neck, brain, renal and peripheral vessels. ... MRI uses a combination of strong magnetic fields and radio waves to produce exquisitely detailed images of any part of the body ... The scanner also produces very detailed 3D images of the whole body including moving organs; bone and blood vessels and can ...
21] Provided ECG gating and breath-holding are effective, reliable and accurate imaging of cardiac function and anatomy is ... Despite the development of cross-sectional imaging techniques, chest radiography remains useful in evaluating cardiac disease. ... Wang L, Yan C, Zhao S, Fang W. Comparison of (99m)Tc-MIBI SPECT/18F-FDG PET imaging and cardiac magnetic resonance imaging in ... Magnetic resonance imaging of ischemic heart disease: why cardiac magnetic resonance imaging will play a significant role in ...
Gated Blood-pool Imaging. Radionuclide ventriculography where scintigraphic data is acquired during repeated cardiac cycles at ... Analysis of right ventricular function is difficult with this technique; that is best evaluated by first-pass ventriculography ... specific times in the cycle, using an electrocardiographic synchronizer or gating device. ...
A simple thresholding technique was used to generate binary images from nongated SPECT images. The K-means cluster ... to validate the gated SPECT cardiac quantification (GSCQ) method in phantoms and patients, and to determine normal values of ... New hybrid count- and geometry-based method for quantification of left ventricular volumes and ejection fraction from ECG-gated ... Section of Cardiovascular Medicine, Department of Internal Medicine, Cardiovascular Nuclear Imaging Laboratory, Yale University ...
... is a new technique for imaging coronary vessels in the human body. Due to the residual cardiac motion, projections being in the ... A gating window is determined at a pre-defined trigger delay relative to the R-peaks with a constant width. In order to achieve ... The purpose of this work is to introduce a simple and efficient image based technique, which is able to determine the optimal ... SPIE 5370, Medical Imaging 2004: Image Processing, (12 May 2004); doi: 10.1117/12.535481. Show Author Affiliations. Babak ...
... of the cardiac vascular tree. This review will provide an overview of these techniques, as well as some practical pointers ... However, our basic understanding of the cardiac microcirculation is hampered by an historic inability to image the microvessels ... However, our basic understanding of the cardiac microcirculation is hampered by an historic inability to image the microvessels ... In this review, we will discuss some of the historic work that took place in the latter part of last century towards cardiac ...
In prospective gating the last part of diastole is not acquired and is missing from the images of a cardiac cycle. This part of ... PC imaging technique utilizes a gradient echo sequence. The images can be acquired during breath-holding or free breathing and ... Either the cine images or the in-plane phase contrast images can be used to plan the location of the through plane image The ... Through plane images are obtained by obtaining an image slice perpendicular to flow. Through plane images show a flow ...
  • Despite the difficulties and known limitations, several image segmentation approaches have been proposed and used in the clinical setting including thresholding, edge detection, region growing, clustering, stochastic models, deformable models, classifiers and several other approaches. (springer.com)
  • Each year, approximately 1.8 million Americans will experience an acute myocardial infarction (AMI), or sudden cardiac death will be their first clinical manifestation of CAD. (appliedradiology.com)
  • The purpose of this article is to review the technical aspects and briefly describe the role of pulmonary MRI in clinical imaging. (appliedradiology.com)
  • Because of improvements in speed and image quality, MRI is now ready for routine clinical use also in the study of pulmonary diseases. (scielo.br)
  • Several imaging techniques may provide the integrated flow/function information, but their degree of certainty varies as well as their impact on clinical decision-making. (escardio.org)
  • There has been much recent interest in obtaining matched information by a single technique in clinical cardiology. (escardio.org)
  • Scientific evaluation of the safety and clinical effectiveness of surface and other specialty coil devices and gating techniques in conjunction with MRI procedures. (ahrq.gov)
  • Supposedly to avoid confusion with nuclear medicine, the clinical NMR imaging tool became known as magnetic resonance imaging (MRI) in the late 1970s. (jci.org)
  • There are many approaches available, related to the sequence of radiofrequency pulses and magnetic field gradients, for the generation of clinical images and spectra by NMR. (jci.org)
  • A comparison and summary of some common clinical imaging sequences is provided in Table 1 . (jci.org)
  • The clinical application of cardiac NMR spectroscopy requires localization of the observed signals to the in situ myocardium to avoid contamination from adjacent tissues. (jci.org)
  • Although the bulk of clinical myocardial spectroscopy has been applied to the evaluation of the metabolites that contain phosphorus, these techniques are applicable to other NMR-visible nuclei, including hydrogen, carbon-13, fluorine-19, and sodium-23. (jci.org)
  • however, the technique is currently not available on MR scanners and thus has limited clinical usefulness. (ajnr.org)
  • ANGIE RV imaging merits further clinical evaluation in PH. (biomedcentral.com)
  • On one hand, breath-hold cardiac cine acquisitions are routinely used in daily clinical protocols. (nature.com)
  • The translational component involves a didactic component, provided by Emory University's Master of Science in Clinical Research program and an Imaging Clinical Trials workshop offered by the Radiological Society of North America. (grantome.com)
  • The program would take place in an environment which is at the cutting edge of medical imaging, cardiology, and biomedical engineering, with extensive clinical, educational and research resources. (grantome.com)
  • A 71-year-old man with hypertension, hypercholesterolemia, and known aortic and peripheral vascular disease was imaged with a LightSpeed 4-slice, multislice CT scanner (GE Medical Systems). (ahajournals.org)
  • This work, which has utilized technology such as spinning-disk confocal and multiphoton microscopy, has-along with some significant advancements in algorithms and software-unlocked our ability to image the "business end" of the cardiac vascular tree. (frontiersin.org)
  • Brilliance Everywhere is a thin-client solution that reportedly delivers the full power of advanced applications such as those used in cardiac, vascular, stroke, colon and lung imaging to "any chair of your choice" such as an iSite PACS workstation, EBW CT workstation or even a connected PC at home. (itnonline.com)
  • Quantitative analysis in nuclear medicine imaging. (springer.com)
  • For quantitative evaluation 3 image series have been acquired: 2 single slice IntraGate™-FLASH cine series, one in 2 chamber and one in 4CV view and one multi-slice IntraGate™-FLASH cine SAX scan. (bruker.com)
  • The researchers said that the new 4D technique takes "crystal-clear" images by using quantitative image data and algorithms that help acquire better images. (healthimaging.com)
  • 9 Quantitative estimates of myocardial blood flow (MBF) for both rest and pharmacological-stress images, and coronary flow reserve (CFR) are added advantages available with PET phase analysis. (springer.com)
  • Quantitative imaging is an increasing need in basic science research as morphological consequences of conditional mutations and microscale environmental alterations initiate subtle but progressive malformations that resemble clinically relevant defects. (wiley.com)
  • Robotic surgical systems and devices are well suited for use in performing minimally invasive medical procedures, as opposed to conventional techniques wherein the patient's body cavity is open to permit the surgeon's hands access to internal organs. (google.ca)
  • Preliminary in vivo study demonstrated that a whole heart coverage of 3D cine imaging can be achieved within 1 min and the technique had excellent performance compared to the standard ECG-triggering and conventional SG methods. (ismrm.org)
  • The conventional stress and rest tomograms were interpreted first by means of a 14-segment scoring system, and then the studies were reinterpreted while the gated images were viewed. (onlinejacc.org)
  • In addition to this finding, the researchers found image noise to be reduced by 60 percent compared with conventional imaging methods used during cardiac gating. (healthimaging.com)
  • Total 8/70,000 cases diagnosed ALCAPA by MDCT exam, all image qualities were acceptable. (scirp.org)
  • Morphologic variants of atrial, ventricular, valvular,arterial and venous structures can be imaged with unsurpassed definition. (appliedradiology.com)
  • Able to evaluate the cardiac structures with great specificity and able to evaluate chamber pressures. (infectiousdiseaseadvisor.com)
  • electrostatic imaging a method of visualizing deep structures of the body, in which an electron beam is passed through the patient and the emerging beam strikes an electrostatically charged plate, dissipating the charge according to the strength of the beam. (thefreedictionary.com)
  • Surface and other specialty coils enhance the quality of MR images, particularly for small structures that require greater spatial resolution. (ahrq.gov)
  • Offers exquisite detail of the valvular structures and helps measure cardiac chamber pressures further detailing underlying cardiac pathology. (clinicalpainadvisor.com)
  • Spatial resolution is defined as the ability to resolve structures that lie next to one another on an image. (avmi.net)
  • Region-based methods have proven necessary for improving segmentation accuracy of neuronal structures in electron microscopy (EM) images. (utah.edu)
  • METHODS: Forty-five WPW patients were enrolled and had gated SPECT MPI pre- and 2-3 days post-RFA. (biomedsearch.com)
  • Methods for image segmentation should be standardized and calibrated. (springer.com)
  • The main limitation of traditional methods in a CTA image for the visualization of coronary artery disease is the inability to provide information about vessel walls [ 1 ]. (hindawi.com)
  • This invention relates generally to methods and apparatus for computerized tomographic imaging, and more particularly to methods and apparatus for retrospectively generating computerized tomographic (CT) images of a moving body part without gating signals. (google.com)
  • The purpose of our investigation was to evaluate the safety of ferumoxytol in children undergoing general anaesthesia for cardiac MRI.METHODS: Medical records of children undergoing general anaesthesia for cardiac MRI were reviewed. (stanford.edu)
  • Regional wall motion was determined through two methods: using Gated SPECT, FBP and OSEM reconstructive methods and changes in frequency and spectrum slope in Metz, Butterworth and Ramp, it creates 42 sets. (scialert.net)
  • Exercising two physical factors of reconstructive methods and filtration in Gated SPECT, significant information can be obtained about cardiac wall motions. (scialert.net)
  • On occasion, this technique provides clinically useful information that is not available with other imaging methods. (annals.org)
  • I was actively involved in developing techniques to measure cerebral activation in PET, assessing aerosol distribution in vivo using 3D methods, measuring changes in mucus clearance rates after therapeutic interventions, and in mapping airways ventilation patterns. (edu.au)
  • More recently, I have been involved in developing techniques and instrumentation for SPECT/CT multimodality imaging and investigating novel methods of measuring and utilising measures of error variance in reconstructed SPECT & PET images. (edu.au)
  • An example of CMR movies in different orientations of a cardiac tumor - in this case, an atrial myxoma . (wikipedia.org)
  • A cardiac MRI and chest MRA was performed to evaluate the etiology of left atrial dilation in the setting of a dilated coronary artery. (scmr.org)
  • The cardiac MRI identified severe left atrial dilation, mild mitral valve insufficiency, and normal bi-ventricular size and systolic function (Movie 3 and Table 1). (scmr.org)
  • Figures 1 B to 1 D show a comparison of SAX views derived from a healthy mouse heart (B) with images obtained from animal models of myocardial infarction (C, D). For this purpose occlusion of the left anterior descending LAD coronary artery was applied. (bruker.com)
  • In this work, we developed an optimized cardiac CEST technique with dramatically shortened scan time (by 10-fold), improved motion registration and CEST signal calculation, and tested its feasibility to detect chronic myocardial infarction in porcine model and also in a patient for the first time. (springer.com)
  • LGE images were acquired as reference for myocardial infarction. (springer.com)
  • We developed a clinically feasible cardiac CEST approach and performed preliminary validation studies in porcine with chronic myocardial infarction. (springer.com)
  • Gadolinium-administration showed no enhancement, a feature required to exclude cardiac malignancies and areas of myocardial infarction. (eurorad.org)
  • Anatomical and functional imaging of myocardial infarction in mice using micro-CT and eXIA 160 contrast agent. (nih.gov)
  • We focus on these properties of eXIA and show its use in imaging myocardial infarction in mice. (nih.gov)
  • This delayed timepoint imaging has been used to quantify the size of the myocardial infarction. (nih.gov)
  • A comparison of cine sequences in a mouse with myocardial infarction (A) and a control mouse (B) for similar axial micro-CT slices over the 10 phases of the cardiac cycle acquired immediately after injection of eXIA 160. (nih.gov)
  • We demonstrate the utility of this technique for in vivo optical sectioning and dual-channel time-lapse fluorescence imaging of cardiac ischemia. (pubmedcentralcanada.ca)
  • In an early SPECT study, no significant differences in LVAS were noted between gated rest and exercise stress studies despite the presence of significant ischemia in 50% of the study population. (springer.com)
  • The difficulty in PET image segmentation is compounded by the low spatial resolution and high noise characteristics of PET images. (springer.com)
  • Black blood imaging can be used to create still-frame images with high spatial resolution for morphologic analysis (Figure 1). (appliedradiology.com)
  • In ASL techniques, saturation, spatial, or adiabatic inversion pulses are applied to water molecules outside the imaging field, and their signal is imaged as they enter the field. (appliedradiology.com)
  • Phase analysis of gated SPECT MPI was used to assess LV dyssynchrony pre- and post-RFA. (biomedsearch.com)
  • CONCLUSION: Phase analysis of gated SPECT MPI demonstrated that LV mechanical dyssynchrony can be present in patients with WPW syndrome. (biomedsearch.com)
  • This study supports further investigation in the relationship between electrical and mechanical activation using EPS and phase analysis of gated SPECT MPI. (biomedsearch.com)
  • A stack of images extending to the cardiac apex isthen acquired during suspended respiration, at a slice thickness of approximately 6 to 8 mm, with 2mm interslice gap. (appliedradiology.com)
  • For patients with renal impairment, pacemakers or other non-MR-compatible devices, gated cardiac CT may be used to better characterize the cardiac mass. (psychiatryadvisor.com)
  • Based on these results, we intend to further characterize autoimmune mechanisms in the pathogenesis of cardiac conduction disease. (uni-heidelberg.de)
  • The method allowed serial in vivo fluorescence imaging of the beating heart in live mice in both confocal and nonlinear modes for several hours. (pubmedcentralcanada.ca)
  • Intravital microscopy, computational advances in optical imaging, and the development of novel molecular probes (new biological reporters 1 and more efficient fluorochromes 2 ) have each contributed to significant insights into in vivo biology. (pubmedcentralcanada.ca)
  • We use this approach to perform in vivo confocal and multiphoton microscopy imaging of the beating murine heart at (sub)cellular resolution. (pubmedcentralcanada.ca)
  • Although bio-optical imaging offers high contrast in visualizing both anatomical and functional information of biological tissues in vivo, bio-optical imaging suffers from short penetration depth due to strong optical scattering. (uwm.edu)
  • The resulting technique was applied to in-vivo breast data obtained with an experimental prototype. (spie.org)
  • Siavash Yazdanfar, Manish D. Kulkarni, and Joseph A. Izatt, "High resolution imaging of in vivo cardiac dynamics using color Doppler optical coherence tomography," Opt. (osapublishing.org)
  • In vivo micro-SPECT imaging and ex vivo triphenyl tetrazolium chloride (TTC) staining provided validation for the micro-CT findings. (nih.gov)
  • Compare the image orientation (4 chamber) with the short axis view of the movie above Scar is best seen after giving a contrast agent, typically one containing gadolinium bound to DTPA. (wikipedia.org)
  • There was no myocardial late gadolinium enhancement (Images 5-7). (scmr.org)
  • Viability imaging was performed after intravenous injection of 0.15 mmol/kg gadolinium to assess the extent of infarction. (biomedsearch.com)
  • BACKGROUND: Ferumoxytol, an "off-label" contrast agent, allows for better cardiac MRI quality as compared with gadolinium-based contrast agents. (stanford.edu)
  • A cardiac MRI (Single-shot and late Gadolinium) demonstrated an aneurysmal right coronary artery graft as a mass adjacent to right heart border and compressing RA. (eurorad.org)
  • No abnormal enhancement on delayed Gadolinium imaging. (eurorad.org)
  • The aims of this study were to present the methodology, to validate the gated SPECT cardiac quantification (GSCQ) method in phantoms and patients, and to determine normal values of LVEF. (nih.gov)
  • RV quantification can be improved by using axial views or, preferably, dedicated RV sequences where the tricuspid valve is imaged in the margin of the slice. (appliedradiology.com)
  • 1 Cardiac computed tomographic (CT) volume doubled between 2002 and 2003, to 485 000 cases, 2 and has continued to grow since then. (ahajournals.org)
  • The K-means cluster classification algorithm was used to separate the LV region from non-LV regions on the binary images. (nih.gov)
  • A computer then uses a sophisticated algorithm to "reconstruct" a 3D image. (utah.edu)
  • This algorithm uses iterative approach to correct the distorted image by using the motion models. (wikipedia.org)
  • Furthermore, using a special algorithm, plenty of information can be obtained about cardiac functional parameters. (scialert.net)
  • The main idea of the current paper is to provide a well-constructed analysis of the article titled "Meta-analysis of thoracic epidural anesthesia versus general anesthesia for cardiac surgery" written by Svircevic, van Dijk, Nierich, Passier, Kalkman, van der Heijden, and Bax in 2011. (bartleby.com)
  • It is a medical technique used to treat shortness of breath (American Thoracic Society). (bartleby.com)
  • Modern techniques for repair of thoracic aneurysms and dissections include an open incision with extracorporeal bypass and aortic clamping. (bartleby.com)
  • For the patient presenting with acute chest pain syndromes, it is advocated, again as a Class IIa recommendation, for persons with chest pain with normal first cardiac enzymes and no acute changes on electrocardiograms to rule out obstructive disease. (renalandurologynews.com)
  • A certain number of phases are acquired for each cardiac cycle. (scmr.org)
  • If an R-R interval is longer than the pre-specified interval, the remaining portion of the cardiac cycle will be truncated and will not be included in the k-space. (scmr.org)
  • By applying this new method in a patient with AF, it makes each cardiac cycle more uniform. (scmr.org)
  • (a) ECG trigger delay is set so that the readout is in the quiescent phase of the cardiac cycle. (springer.com)
  • This essentially assesses the dispersion in the timing of myocardial contraction in individual segments during a cardiac cycle. (springer.com)
  • The PI hypothesizes that US, which provides real-time data similar to electrocardiography (ECG), can directly evaluate cardiac mechanical motion and would be more reliable than ECG at determining relative cardiac akinesia within a cardiac cycle. (grantome.com)
  • The dog's ECG is seen along the top of the image with the numbers and boxes representing the slices acquired during that cardiac cycle. (avmi.net)
  • Although these frame rates are adequate to assess cardiac morphology and certain functional aspects, they do not allow the resolution of all cardiac mechanical events, as some of them are very short-lived. (onlinejacc.org)