Myocytes, Cardiac: Striated muscle cells found in the heart. They are derived from cardiac myoblasts (MYOBLASTS, CARDIAC).Cardiac Output: The volume of BLOOD passing through the HEART per unit of time. It is usually expressed as liters (volume) per minute so as not to be confused with STROKE VOLUME (volume per beat).Heart: The hollow, muscular organ that maintains the circulation of the blood.Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.Cardiac Surgical Procedures: Surgery performed on the heart.Death, Sudden, Cardiac: Unexpected rapid natural death due to cardiovascular collapse within one hour of initial symptoms. It is usually caused by the worsening of existing heart diseases. The sudden onset of symptoms, such as CHEST PAIN and CARDIAC ARRHYTHMIAS, particularly VENTRICULAR TACHYCARDIA, can lead to the loss of consciousness and cardiac arrest followed by biological death. (from Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 7th ed., 2005)Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.Cardiac Tamponade: Compression of the heart by accumulated fluid (PERICARDIAL EFFUSION) or blood (HEMOPERICARDIUM) in the PERICARDIUM surrounding the heart. The affected cardiac functions and CARDIAC OUTPUT can range from minimal to total hemodynamic collapse.Cardiac Pacing, Artificial: Regulation of the rate of contraction of the heart muscles by an artificial pacemaker.Heart Diseases: Pathological conditions involving the HEART including its structural and functional abnormalities.Myocardium: The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.Cardiac Catheterization: Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.Myocardial Contraction: Contractile activity of the MYOCARDIUM.Heart Arrest: Cessation of heart beat or MYOCARDIAL CONTRACTION. If it is treated within a few minutes, heart arrest can be reversed in most cases to normal cardiac rhythm and effective circulation.Heart Ventricles: The lower right and left chambers of the heart. The right ventricle pumps venous BLOOD into the LUNGS and the left ventricle pumps oxygenated blood into the systemic arterial circulation.Myoblasts, Cardiac: Precursor cells destined to differentiate into cardiac myocytes (MYOCYTES, CARDIAC).Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.Cardiomyopathies: A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).Cardiac Myosins: Myosin type II isoforms found in cardiac muscle.Cardiac Imaging Techniques: Visualization of the heart structure and cardiac blood flow for diagnostic evaluation or to guide cardiac procedures via techniques including ENDOSCOPY (cardiac endoscopy, sometimes refered to as cardioscopy), RADIONUCLIDE IMAGING; MAGNETIC RESONANCE IMAGING; TOMOGRAPHY; or ULTRASONOGRAPHY.Electrocardiography: Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.Cardiac Glycosides: Cyclopentanophenanthrenes with a 5- or 6-membered lactone ring attached at the 17-position and SUGARS attached at the 3-position. Plants they come from have long been used in congestive heart failure. They increase the force of cardiac contraction without significantly affecting other parameters, but are very toxic at larger doses. Their mechanism of action usually involves inhibition of the NA(+)-K(+)-EXCHANGING ATPASE and they are often used in cell biological studies for that purpose.Heart Rate: The number of times the HEART VENTRICLES contract per unit of time, usually per minute.Echocardiography: Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.Cardiac Output, Low: A state of subnormal or depressed cardiac output at rest or during stress. It is a characteristic of CARDIOVASCULAR DISEASES, including congenital, valvular, rheumatic, hypertensive, coronary, and cardiomyopathic. The serious form of low cardiac output is characterized by marked reduction in STROKE VOLUME, and systemic vasoconstriction resulting in cold, pale, and sometimes cyanotic extremities.Out-of-Hospital Cardiac Arrest: Occurrence of heart arrest in an individual when there is no immediate access to medical personnel or equipment.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Hemodynamics: The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).Cardiac Volume: The volume of the HEART, usually relating to the volume of BLOOD contained within it at various periods of the cardiac cycle. The amount of blood ejected from a ventricle at each beat is STROKE VOLUME.Ventricular Remodeling: The geometric and structural changes that the HEART VENTRICLES undergo, usually following MYOCARDIAL INFARCTION. It comprises expansion of the infarct and dilatation of the healthy ventricle segments. While most prevalent in the left ventricle, it can also occur in the right ventricle.Heart Transplantation: The transference of a heart from one human or animal to another.Troponin I: One of the three polypeptide chains that make up the TROPONIN complex. It inhibits F-actin-myosin interactions.Ventricular Function, Left: The hemodynamic and electrophysiological action of the left HEART VENTRICLE. Its measurement is an important aspect of the clinical evaluation of patients with heart disease to determine the effects of the disease on cardiac performance.Heart Defects, Congenital: Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.Stroke Volume: The amount of BLOOD pumped out of the HEART per beat, not to be confused with cardiac output (volume/time). It is calculated as the difference between the end-diastolic volume and the end-systolic volume.Blood Pressure: PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.Cardiac Resynchronization Therapy: The restoration of the sequential order of contraction and relaxation of the HEART ATRIA and HEART VENTRICLES by atrio-biventricular pacing.Heart Function Tests: Examinations used to diagnose and treat heart conditions.Troponin T: One of the three polypeptide chains that make up the TROPONIN complex. It is a cardiac-specific protein that binds to TROPOMYOSIN. It is released from damaged or injured heart muscle cells (MYOCYTES, CARDIAC). Defects in the gene encoding troponin T result in FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.Heart Conduction System: An impulse-conducting system composed of modified cardiac muscle, having the power of spontaneous rhythmicity and conduction more highly developed than the rest of the heart.Cardiopulmonary Resuscitation: The artificial substitution of heart and lung action as indicated for HEART ARREST resulting from electric shock, DROWNING, respiratory arrest, or other causes. The two major components of cardiopulmonary resuscitation are artificial ventilation (RESPIRATION, ARTIFICIAL) and closed-chest CARDIAC MASSAGE.Heart Neoplasms: Tumors in any part of the heart. They include primary cardiac tumors and metastatic tumors to the heart. Their interference with normal cardiac functions can cause a wide variety of symptoms including HEART FAILURE; CARDIAC ARRHYTHMIAS; or EMBOLISM.Cardiac Care Facilities: Institutions specializing in the care of patients with heart disorders.Dogs: The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)Cardiomyopathy, Dilated: A form of CARDIAC MUSCLE disease that is characterized by ventricular dilation, VENTRICULAR DYSFUNCTION, and HEART FAILURE. Risk factors include SMOKING; ALCOHOL DRINKING; HYPERTENSION; INFECTION; PREGNANCY; and mutations in the LMNA gene encoding LAMIN TYPE A, a NUCLEAR LAMINA protein.Ventricular Dysfunction, Left: A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.Cardiotonic Agents: Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE).Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Cardiac Electrophysiology: The study of the electrical activity and characteristics of the HEART; MYOCARDIUM; and CARDIOMYOCYTES.Models, Cardiovascular: Theoretical representations that simulate the behavior or activity of the cardiovascular system, processes, or phenomena; includes the use of mathematical equations, computers and other electronic equipment.Fibrosis: Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.Rats, Sprague-Dawley: A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.Fetal Heart: The heart of the fetus of any viviparous animal. It refers to the heart in the postembryonic period and is differentiated from the embryonic heart (HEART/embryology) only on the basis of time.Calcium: A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.Heart Atria: The chambers of the heart, to which the BLOOD returns from the circulation.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Ventricular Function: The hemodynamic and electrophysiological action of the HEART VENTRICLES.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Cells, Cultured: Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.Heart Injuries: General or unspecified injuries to the heart.Cardiopulmonary Bypass: Diversion of the flow of blood from the entrance of the right atrium directly to the aorta (or femoral artery) via an oxygenator thus bypassing both the heart and lungs.Troponin: One of the minor protein components of skeletal muscle. Its function is to serve as the calcium-binding component in the troponin-tropomyosin B-actin-myosin complex by conferring calcium sensitivity to the cross-linked actin and myosin filaments.Hypertrophy, Left Ventricular: Enlargement of the LEFT VENTRICLE of the heart. This increase in ventricular mass is attributed to sustained abnormal pressure or volume loads and is a contributor to cardiovascular morbidity and mortality.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Myocarditis: Inflammatory processes of the muscular walls of the heart (MYOCARDIUM) which result in injury to the cardiac muscle cells (MYOCYTES, CARDIAC). Manifestations range from subclinical to sudden death (DEATH, SUDDEN). Myocarditis in association with cardiac dysfunction is classified as inflammatory CARDIOMYOPATHY usually caused by INFECTION, autoimmune diseases, or responses to toxic substances. Myocarditis is also a common cause of DILATED CARDIOMYOPATHY and other cardiomyopathies.Mice, Transgenic: Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.Sarcomeres: The repeating contractile units of the MYOFIBRIL, delimited by Z bands along its length.Atrial Natriuretic Factor: A potent natriuretic and vasodilatory peptide or mixture of different-sized low molecular weight PEPTIDES derived from a common precursor and secreted mainly by the HEART ATRIUM. All these peptides share a sequence of about 20 AMINO ACIDS.Muscle Proteins: The protein constituents of muscle, the major ones being ACTINS and MYOSINS. More than a dozen accessory proteins exist including TROPONIN; TROPOMYOSIN; and DYSTROPHIN.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Mitochondria, Heart: The mitochondria of the myocardium.Heart Valves: Flaps of tissue that prevent regurgitation of BLOOD from the HEART VENTRICLES to the HEART ATRIA or from the PULMONARY ARTERIES or AORTA to the ventricles.Pericardium: A conical fibro-serous sac surrounding the HEART and the roots of the great vessels (AORTA; VENAE CAVAE; PULMONARY ARTERY). Pericardium consists of two sacs: the outer fibrous pericardium and the inner serous pericardium. The latter consists of an outer parietal layer facing the fibrous pericardium, and an inner visceral layer (epicardium) resting next to the heart, and a pericardial cavity between these two layers.Predictive Value of Tests: In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.Rats, Wistar: A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.Pacemaker, Artificial: A device designed to stimulate, by electric impulses, contraction of the heart muscles. It may be temporary (external) or permanent (internal or internal-external).Edema, Cardiac: Abnormal fluid retention by the body due to impaired cardiac function or heart failure. It is usually characterized by increase in venous and capillary pressure, and swollen legs when standing. It is different from the generalized edema caused by renal dysfunction (NEPHROTIC SYNDROME).Biological Markers: Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.Mice, Inbred C57BLMagnetic Resonance Imaging, Cine: A type of imaging technique used primarily in the field of cardiology. By coordinating the fast gradient-echo MRI sequence with retrospective ECG-gating, numerous short time frames evenly spaced in the cardiac cycle are produced. These images are laced together in a cinematic display so that wall motion of the ventricles, valve motion, and blood flow patterns in the heart and great vessels can be visualized.Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.Ventricular Fibrillation: A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.Animals, Newborn: Refers to animals in the period of time just after birth.Coronary Circulation: The circulation of blood through the CORONARY VESSELS of the HEART.Natriuretic Peptide, Brain: A PEPTIDE that is secreted by the BRAIN and the HEART ATRIA, stored mainly in cardiac ventricular MYOCARDIUM. It can cause NATRIURESIS; DIURESIS; VASODILATION; and inhibits secretion of RENIN and ALDOSTERONE. It improves heart function. It contains 32 AMINO ACIDS.Myocardial Reperfusion Injury: Damage to the MYOCARDIUM resulting from MYOCARDIAL REPERFUSION (restoration of blood flow to ischemic areas of the HEART.) Reperfusion takes place when there is spontaneous thrombolysis, THROMBOLYTIC THERAPY, collateral flow from other coronary vascular beds, or reversal of vasospasm.Cardiomyopathy, Hypertrophic: A form of CARDIAC MUSCLE disease, characterized by left and/or right ventricular hypertrophy (HYPERTROPHY, LEFT VENTRICULAR; HYPERTROPHY, RIGHT VENTRICULAR), frequent asymmetrical involvement of the HEART SEPTUM, and normal or reduced left ventricular volume. Risk factors include HYPERTENSION; AORTIC STENOSIS; and gene MUTATION; (FAMILIAL HYPERTROPHIC CARDIOMYOPATHY).Mice, Knockout: Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.Ventricular Pressure: The pressure within a CARDIAC VENTRICLE. Ventricular pressure waveforms can be measured in the beating heart by catheterization or estimated using imaging techniques (e.g., DOPPLER ECHOCARDIOGRAPHY). The information is useful in evaluating the function of the MYOCARDIUM; CARDIAC VALVES; and PERICARDIUM, particularly with simultaneous measurement of other (e.g., aortic or atrial) pressures.Risk Assessment: The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)Coronary Artery Bypass: Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.Sarcolemma: The excitable plasma membrane of a muscle cell. (Glick, Glossary of Biochemistry and Molecular Biology, 1990)Myosin Heavy Chains: The larger subunits of MYOSINS. The heavy chains have a molecular weight of about 230 kDa and each heavy chain is usually associated with a dissimilar pair of MYOSIN LIGHT CHAINS. The heavy chains possess actin-binding and ATPase activity.Coronary Vessels: The veins and arteries of the HEART.Signal Transduction: The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.Thermodilution: Measurement of blood flow based on induction at one point of the circulation of a known change in the intravascular heat content of flowing blood and detection of the resultant change in temperature at a point downstream.Diastole: Post-systolic relaxation of the HEART, especially the HEART VENTRICLES.Echocardiography, Doppler: Measurement of intracardiac blood flow using an M-mode and/or two-dimensional (2-D) echocardiogram while simultaneously recording the spectrum of the audible Doppler signal (e.g., velocity, direction, amplitude, intensity, timing) reflected from the moving column of red blood cells.GATA4 Transcription Factor: A GATA transcription factor that is expressed in the MYOCARDIUM of developing heart and has been implicated in the differentiation of CARDIAC MYOCYTES. GATA4 is activated by PHOSPHORYLATION and regulates transcription of cardiac-specific genes.Ventricular Dysfunction: A condition in which HEART VENTRICLES exhibit impaired function.Thoracic Surgery: A surgical specialty concerned with diagnosis and treatment of disorders of the heart, lungs, and esophagus. Two major types of thoracic surgery are classified as pulmonary and cardiovascular.Systole: Period of contraction of the HEART, especially of the HEART VENTRICLES.Pericardial Effusion: Fluid accumulation within the PERICARDIUM. Serous effusions are associated with pericardial diseases. Hemopericardium is associated with trauma. Lipid-containing effusion (chylopericardium) results from leakage of THORACIC DUCT. Severe cases can lead to CARDIAC TAMPONADE.NAV1.5 Voltage-Gated Sodium Channel: A voltage-gated sodium channel subtype that mediates the sodium ion PERMEABILITY of CARDIOMYOCYTES. Defects in the SCN5A gene, which codes for the alpha subunit of this sodium channel, are associated with a variety of CARDIAC DISEASES that result from loss of sodium channel function.Rabbits: The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.Endomyocardial Fibrosis: A condition characterized by the thickening of the ventricular ENDOCARDIUM and subendocardium (MYOCARDIUM), seen mostly in children and young adults in the TROPICAL CLIMATE. The fibrous tissue extends from the apex toward and often involves the HEART VALVES causing restrictive blood flow into the respective ventricles (CARDIOMYOPATHY, RESTRICTIVE).Prognosis: A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.Adrenergic beta-Antagonists: Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.RNA, Messenger: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.Exercise Test: Controlled physical activity which is performed in order to allow assessment of physiological functions, particularly cardiovascular and pulmonary, but also aerobic capacity. Maximal (most intense) exercise is usually required but submaximal exercise is also used.Autonomic Nervous System: The ENTERIC NERVOUS SYSTEM; PARASYMPATHETIC NERVOUS SYSTEM; and SYMPATHETIC NERVOUS SYSTEM taken together. Generally speaking, the autonomic nervous system regulates the internal environment during both peaceful activity and physical or emotional stress. Autonomic activity is controlled and integrated by the CENTRAL NERVOUS SYSTEM, especially the HYPOTHALAMUS and the SOLITARY NUCLEUS, which receive information relayed from VISCERAL AFFERENTS.Electrophysiologic Techniques, Cardiac: Methods to induce and measure electrical activities at specific sites in the heart to diagnose and treat problems with the heart's electrical system.Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.Creatine Kinase: A transferase that catalyzes formation of PHOSPHOCREATINE from ATP + CREATINE. The reaction stores ATP energy as phosphocreatine. Three cytoplasmic ISOENZYMES have been identified in human tissues: the MM type from SKELETAL MUSCLE, the MB type from myocardial tissue and the BB type from nervous tissue as well as a mitochondrial isoenzyme. Macro-creatine kinase refers to creatine kinase complexed with other serum proteins.Bradycardia: Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.Vascular Resistance: The force that opposes the flow of BLOOD through a vascular bed. It is equal to the difference in BLOOD PRESSURE across the vascular bed divided by the CARDIAC OUTPUT.Oxygen Consumption: The rate at which oxygen is used by a tissue; microliters of oxygen STPD used per milligram of tissue per hour; the rate at which oxygen enters the blood from alveolar gas, equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body. (Stedman, 25th ed, p346)Action Potentials: Abrupt changes in the membrane potential that sweep along the CELL MEMBRANE of excitable cells in response to excitation stimuli.Muscle Cells: Mature contractile cells, commonly known as myocytes, that form one of three kinds of muscle. The three types of muscle cells are skeletal (MUSCLE FIBERS, SKELETAL), cardiac (MYOCYTES, CARDIAC), and smooth (MYOCYTES, SMOOTH MUSCLE). They are derived from embryonic (precursor) muscle cells called MYOBLASTS.Coronary Artery Disease: Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.Myofibrils: The long cylindrical contractile organelles of STRIATED MUSCLE cells composed of ACTIN FILAMENTS; MYOSIN filaments; and other proteins organized in arrays of repeating units called SARCOMERES .Sarcoplasmic Reticulum Calcium-Transporting ATPases: Calcium-transporting ATPases that catalyze the active transport of CALCIUM into the SARCOPLASMIC RETICULUM vesicles from the CYTOPLASM. They are primarily found in MUSCLE CELLS and play a role in the relaxation of MUSCLES.Resuscitation: The restoration to life or consciousness of one apparently dead. (Dorland, 27th ed)Endocardium: The innermost layer of the heart, comprised of endothelial cells.Adrenergic beta-Agonists: Drugs that selectively bind to and activate beta-adrenergic receptors.Troponin C: One of the three polypeptide chains that make up the TROPONIN complex of skeletal muscle. It is a calcium-binding protein.Vagus Nerve: The 10th cranial nerve. The vagus is a mixed nerve which contains somatic afferents (from skin in back of the ear and the external auditory meatus), visceral afferents (from the pharynx, larynx, thorax, and abdomen), parasympathetic efferents (to the thorax and abdomen), and efferents to striated muscle (of the larynx and pharynx).Anti-Arrhythmia Agents: Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.Ventricular Myosins: Isoforms of MYOSIN TYPE II, specifically found in the ventricular muscle of the HEART. Defects in the genes encoding ventricular myosins result in FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.Receptors, Adrenergic, beta: One of two major pharmacologically defined classes of adrenergic receptors. The beta adrenergic receptors play an important role in regulating CARDIAC MUSCLE contraction, SMOOTH MUSCLE relaxation, and GLYCOGENOLYSIS.Defibrillators, Implantable: Implantable devices which continuously monitor the electrical activity of the heart and automatically detect and terminate ventricular tachycardia (TACHYCARDIA, VENTRICULAR) and VENTRICULAR FIBRILLATION. They consist of an impulse generator, batteries, and electrodes.Organ Size: The measurement of an organ in volume, mass, or heaviness.Death: Irreversible cessation of all bodily functions, manifested by absence of spontaneous breathing and total loss of cardiovascular and cerebral functions.Cardiac Resynchronization Therapy Devices: Types of artificial pacemakers with implantable leads to be placed at multiple intracardial sites. They are used to treat various cardiac conduction disturbances which interfere with the timing of contraction of the ventricles. They may or may not include defibrillating electrodes (IMPLANTABLE DEFIBRILLATORS) as well.Ryanodine Receptor Calcium Release Channel: A tetrameric calcium release channel in the SARCOPLASMIC RETICULUM membrane of SMOOTH MUSCLE CELLS, acting oppositely to SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES. It is important in skeletal and cardiac excitation-contraction coupling and studied by using RYANODINE. Abnormalities are implicated in CARDIAC ARRHYTHMIAS and MUSCULAR DISEASES.Advanced Cardiac Life Support: The use of sophisticated methods and equipment to treat cardiopulmonary arrest. Advanced Cardiac Life Support (ACLS) includes the use of specialized equipment to maintain the airway, early defibrillation and pharmacological therapy.Myxoma: A benign neoplasm derived from connective tissue, consisting chiefly of polyhedral and stellate cells that are loosely embedded in a soft mucoid matrix, thereby resembling primitive mesenchymal tissue. It occurs frequently intramuscularly where it may be mistaken for a sarcoma. It appears also in the jaws and the skin. (From Stedman, 25th ed)Papillary Muscles: Conical muscular projections from the walls of the cardiac ventricles, attached to the cusps of the atrioventricular valves by the chordae tendineae.Coronary Angiography: Radiography of the vascular system of the heart muscle after injection of a contrast medium.Angiotensin II: An octapeptide that is a potent but labile vasoconstrictor. It is produced from angiotensin I after the removal of two amino acids at the C-terminal by ANGIOTENSIN CONVERTING ENZYME. The amino acid in position 5 varies in different species. To block VASOCONSTRICTION and HYPERTENSION effect of angiotensin II, patients are often treated with ACE INHIBITORS or with ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS.Dose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.Calcium Channels, L-Type: Long-lasting voltage-gated CALCIUM CHANNELS found in both excitable and nonexcitable tissue. They are responsible for normal myocardial and vascular smooth muscle contractility. Five subunits (alpha-1, alpha-2, beta, gamma, and delta) make up the L-type channel. The alpha-1 subunit is the binding site for calcium-based antagonists. Dihydropyridine-based calcium antagonists are used as markers for these binding sites.Tachycardia, Ventricular: An abnormally rapid ventricular rhythm usually in excess of 150 beats per minute. It is generated within the ventricle below the BUNDLE OF HIS, either as autonomic impulse formation or reentrant impulse conduction. Depending on the etiology, onset of ventricular tachycardia can be paroxysmal (sudden) or nonparoxysmal, its wide QRS complexes can be uniform or polymorphic, and the ventricular beating may be independent of the atrial beating (AV dissociation).Purkinje Fibers: Modified cardiac muscle fibers composing the terminal portion of the heart conduction system.3-Iodobenzylguanidine: A guanidine analog with specific affinity for tissues of the sympathetic nervous system and related tumors. The radiolabeled forms are used as antineoplastic agents and radioactive imaging agents. (Merck Index, 12th ed) MIBG serves as a neuron-blocking agent which has a strong affinity for, and retention in, the adrenal medulla and also inhibits ADP-ribosyltransferase.Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.Reproducibility of Results: The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.Guinea Pigs: A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research.Heart Valve Diseases: Pathological conditions involving any of the various HEART VALVES and the associated structures (PAPILLARY MUSCLES and CHORDAE TENDINEAE).Sodium Channels: Ion channels that specifically allow the passage of SODIUM ions. A variety of specific sodium channel subtypes are involved in serving specialized functions such as neuronal signaling, CARDIAC MUSCLE contraction, and KIDNEY function.Cardiovascular System: The HEART and the BLOOD VESSELS by which BLOOD is pumped and circulated through the body.Electric Countershock: An electrical current applied to the HEART to terminate a disturbance of its rhythm, ARRHYTHMIAS, CARDIAC. (Stedman, 25th ed)Gene Expression Regulation: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.Myosins: A diverse superfamily of proteins that function as translocating proteins. They share the common characteristics of being able to bind ACTINS and hydrolyze MgATP. Myosins generally consist of heavy chains which are involved in locomotion, and light chains which are involved in regulation. Within the structure of myosin heavy chain are three domains: the head, the neck and the tail. The head region of the heavy chain contains the actin binding domain and MgATPase domain which provides energy for locomotion. The neck region is involved in binding the light-chains. The tail region provides the anchoring point that maintains the position of the heavy chain. The superfamily of myosins is organized into structural classes based upon the type and arrangement of the subunits they contain.Heart Block: Impaired conduction of cardiac impulse that can occur anywhere along the conduction pathway, such as between the SINOATRIAL NODE and the right atrium (SA block) or between atria and ventricles (AV block). Heart blocks can be classified by the duration, frequency, or completeness of conduction block. Reversibility depends on the degree of structural or functional defects.Norepinephrine: Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.Sodium-Calcium Exchanger: An electrogenic ion exchange protein that maintains a steady level of calcium by removing an amount of calcium equal to that which enters the cells. It is widely distributed in most excitable membranes, including the brain and heart.Defibrillators: Cardiac electrical stimulators that apply brief high-voltage electroshocks to the HEART. These stimulators are used to restore normal rhythm and contractile function in hearts of patients who are experiencing VENTRICULAR FIBRILLATION or ventricular tachycardia (TACHYCARDIA, VENTRICULAR) that is not accompanied by a palpable PULSE. Some defibrillators may also be used to correct certain noncritical dysrhythmias (called synchronized defibrillation or CARDIOVERSION), using relatively low-level discharges synchronized to the patient's ECG waveform. (UMDNS, 2003)Hypothermia, Induced: Abnormally low BODY TEMPERATURE that is intentionally induced in warm-blooded animals by artificial means. In humans, mild or moderate hypothermia has been used to reduce tissue damages, particularly after cardiac or spinal cord injuries and during subsequent surgeries.Analysis of Variance: A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.Magnetic Resonance Imaging: Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.Cardiology: The study of the heart, its physiology, and its functions.Emergency Medical Services: Services specifically designed, staffed, and equipped for the emergency care of patients.Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)Electrophysiology: The study of the generation and behavior of electrical charges in living organisms particularly the nervous system and the effects of electricity on living organisms.Calcium Signaling: Signal transduction mechanisms whereby calcium mobilization (from outside the cell or from intracellular storage pools) to the cytoplasm is triggered by external stimuli. Calcium signals are often seen to propagate as waves, oscillations, spikes, sparks, or puffs. The calcium acts as an intracellular messenger by activating calcium-responsive proteins.Models, Animal: Non-human animals, selected because of specific characteristics, for use in experimental research, teaching, or testing.Heart Massage: Rhythmic compression of the heart by pressure applied manually over the sternum (closed heart massage) or directly to the heart through an opening in the chest wall (open heart massage). It is done to reinstate and maintain circulation. (Dorland, 28th ed)Cardiac-Gated Imaging Techniques: Timing the acquisition of imaging data to specific points in the cardiac cycle to minimize image blurring and other motion artifacts.Electrocardiography, Ambulatory: Method in which prolonged electrocardiographic recordings are made on a portable tape recorder (Holter-type system) or solid-state device ("real-time" system), while the patient undergoes normal daily activities. It is useful in the diagnosis and management of intermittent cardiac arrhythmias and transient myocardial ischemia.Calcium-Binding Proteins: Proteins to which calcium ions are bound. They can act as transport proteins, regulator proteins, or activator proteins. They typically contain EF HAND MOTIFS.Gene Expression: The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.Rhabdomyoma: A benign tumor derived from striated muscle. It is extremely rare, generally occurring in the tongue, neck muscles, larynx, uvula, nasal cavity, axilla, vulva, and heart. These tumors are treated by simple excision. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1354)Perfusion: Treatment process involving the injection of fluid into an organ or tissue.Cardiography, Impedance: A type of impedance plethysmography in which bioelectrical impedance is measured between electrodes positioned around the neck and around the lower thorax. It is used principally to calculate stroke volume and cardiac volume, but it is also related to myocardial contractility, thoracic fluid content, and circulation to the extremities.Death, Sudden: The abrupt cessation of all vital bodily functions, manifested by the permanent loss of total cerebral, respiratory, and cardiovascular functions.Cardiovascular Agents: Agents that affect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume.Phosphorylation: The introduction of a phosphoryl group into a compound through the formation of an ester bond between the compound and a phosphorus moiety.Phenotype: The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.Blood Circulation: The movement of the BLOOD as it is pumped through the CARDIOVASCULAR SYSTEM.Swine: Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).Muscle, Skeletal: A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.Survival Rate: The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.Monitoring, Physiologic: The continuous measurement of physiological processes, blood pressure, heart rate, renal output, reflexes, respiration, etc., in a patient or experimental animal; includes pharmacologic monitoring, the measurement of administered drugs or their metabolites in the blood, tissues, or urine.Dobutamine: A catecholamine derivative with specificity for BETA-1 ADRENERGIC RECEPTORS. It is commonly used as a cardiotonic agent after CARDIAC SURGERY and during DOBUTAMINE STRESS ECHOCARDIOGRAPHY.Postoperative Period: The period following a surgical operation.Membrane Potentials: The voltage differences across a membrane. For cellular membranes they are computed by subtracting the voltage measured outside the membrane from the voltage measured inside the membrane. They result from differences of inside versus outside concentration of potassium, sodium, chloride, and other ions across cells' or ORGANELLES membranes. For excitable cells, the resting membrane potentials range between -30 and -100 millivolts. Physical, chemical, or electrical stimuli can make a membrane potential more negative (hyperpolarization), or less negative (depolarization).Fibroblasts: Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.Atrial Fibrillation: Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.Diabetic Cardiomyopathies: Diabetes complications in which VENTRICULAR REMODELING in the absence of CORONARY ATHEROSCLEROSIS and hypertension results in cardiac dysfunctions, typically LEFT VENTRICULAR DYSFUNCTION. The changes also result in myocardial hypertrophy, myocardial necrosis and fibrosis, and collagen deposition due to impaired glucose tolerance.Cardiac Output, High: A state of elevated cardiac output due to conditions of either increased hemodynamic demand or reduced cardiac oxygen output. These conditions may include ANEMIA; ARTERIOVENOUS FISTULA; THYROTOXICOSIS; PREGNANCY; EXERCISE; FEVER; and ANOXIA. In time, compensatory changes of the heart can lead to pathological form of high cardiac output and eventual HEART FAILURE.Tachycardia: Abnormally rapid heartbeat, usually with a HEART RATE above 100 beats per minute for adults. Tachycardia accompanied by disturbance in the cardiac depolarization (cardiac arrhythmia) is called tachyarrhythmia.Potassium Channels: Cell membrane glycoproteins that are selectively permeable to potassium ions. At least eight major groups of K channels exist and they are made up of dozens of different subunits.Blotting, Western: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.Heart Arrest, Induced: A procedure to stop the contraction of MYOCARDIUM during HEART SURGERY. It is usually achieved with the use of chemicals (CARDIOPLEGIC SOLUTIONS) or cold temperature (such as chilled perfusate).Patch-Clamp Techniques: An electrophysiologic technique for studying cells, cell membranes, and occasionally isolated organelles. All patch-clamp methods rely on a very high-resistance seal between a micropipette and a membrane; the seal is usually attained by gentle suction. The four most common variants include on-cell patch, inside-out patch, outside-out patch, and whole-cell clamp. Patch-clamp methods are commonly used to voltage clamp, that is control the voltage across the membrane and measure current flow, but current-clamp methods, in which the current is controlled and the voltage is measured, are also used.
Chen, Che-Hong; Sun, Lihan; Mochly-Rosen, Daria (2010-10-01). "Mitochondrial aldehyde dehydrogenase and cardiac diseases". ... Cardiovascular Research. 88 (1): 51-57. doi:10.1093/cvr/cvq192. ISSN 0008-6363. PMC 2936126 . PMID 20558439. Goedde, HW; ...
There may initially be a tachycardia as a compensatory mechanism to try to keep the cardiac output constant. Palpate radial or ... Cardiovascular research. 42 (3): 583-90. doi:10.1016/s0008-6363(99)00011-5. PMID 10533597. Bates (Bates). ... That was supposed to betoken the end.... Euler, DE (June 1999). "Cardiac alternans: mechanisms and pathophysiological ...
Patrick M. McCarthy, MD is a cardiac surgeon, executive director of the Bluhm Cardiovascular Institute at Northwestern Medicine ... He completed a residency in general surgery and a fellowship in thoracic and cardiovascular surgery at Mayo Clinic, and a ... "Cardiac Valve Innovations". Innovation and New Ventures - Northwestern University. Retrieved 30 October 2017. McCarthy, PM (9 ... Cardiovascular interventions. 10 (1): 64-65. doi:10.1016/j.jcin.2016.11.018. PMID 28057287. "Edwards MC3 Tricuspid Annuloplasty ...
Klabunde, RE (2007-04-05). "Cardiac Valve Disease". Cardiovascular Physiology Concepts. Richard E. Klabunde. Retrieved 2010-08- ... The semilunar valves (the pulmonary and aortic valves) are formed from four thickenings at the cardiac end of the truncus ... Heart valves are situated around the fibrous rings of the cardiac skeleton. The valves incorporate leaflets or cusps, which are ... Different forms are associated with cardiovascular disease, connective tissue disorders and hypertension. The symptoms of the ...
Cardiac Interventions Today. Retrieved 2017-06-22. "Cardiovascular diseases (CVDs)". World Health Organization. Retrieved 2017- ... 1962 The first synchronous cardiac pacemaker co-developed by Cordis is implanted in a patient. 1970s Cordis introduces the ... "Cardiac Interventions Today - Cardinal Health Announces Strategic Distribution Agreements in International Markets". ... which include offerings in the cardiovascular, wound management, and orthopedics areas." Senior Vice President of equity ...
Diagnosis of CAD and various cardiac abnormalities. Identifying location and degree of CAD in patients with a history of CAD. ... Cardiovascular Imaging. 2 (3): 283-285. doi:10.1016/j.jcmg.2009.01.002 . PMID 19356572. Bisi, G; Sciagrà, R; Santoro, GM; ... This scan is done in conjunction with a cardiac stress test. Planar techniques, such as conventional scintigraphy, are rarely ... First, radioactive substances could be used to determine cardiac physiology (function) and should be done so with the least ...
19 December 2011). "Pediatric Cardiovascular Medicine". John Wiley & Sons. Retrieved 4 August 2016. CS1 maint: Uses editors ... "Uganda Heart Institute starts cardiac catheterization". New Vision. Kampala. Retrieved 4 August 2016. James H. Moller, Julien I ...
Cardiovascular Physiology Concepts. ISBN 1451113846. Klabunde, Richard. "Cardiac Inotropy (Contractility)". Cardiovascular ... Myocardial contractility represents the innate ability of the heart muscle (cardiac muscle or myocardium) to contract. The ... which process determines the concentration of calcium ions in the cytosol of cardiac muscle cells. The factors causing an ... is done primarily through increasing the influx of calcium or maintaining higher calcium levels in the cytosol of cardiac ...
"What Is Sudden Cardiac Arrest?". NHLBI. 22 June 2016. Archived from the original on 28 July 2016. Retrieved 16 August 2016. ... Practical Cardiovascular Pathology. Lippincott Williams & Wilkins. 2010. p. 148. ISBN 9781605478418. Archived from the original ... For example, mutations in the cardiac desmosomal genes as well as in the DES gene may cause arrhythmogenic right ventricular ... Those affected are at an increased risk of sudden cardiac death. Types of cardiomyopathy include hypertrophic cardiomyopathy, ...
"Sodium-Calcium Exchange in Cardiac Cells". Cardiovascular Physiology Concepts. Jimp Studio. Retrieved May 3, 2015. ... Antiarins are cardiac glycoside poisons produced by the upas tree (Antiaris toxicaria). There are two forms, α-antiarin and β- ... β-Antiarin, a cardiac glycoside steroid, can be isolated from upas tree latex (Antiaris toxicaria). Its use ranges from medical ... The cardiac cell exhibits a positive potential during ventricular systole, becomes depolarized, and permits calcium ions to ...
... and cardiac hypertrophy, another illness may be present). Athlete's heart is not the cause of sudden cardiac death during or ... Athletic Heart Syndrome". Cardiovascular Medicine Chapter. 27 January 2008, here online Archived 26 May 2008 at the Wayback ... "Left Ventricular Speckle Tracking-Derived Cardiac Strain and Cardiac Twist Mechanics in Athletes: A Systematic Review and Meta- ... Cardiac output, the amount of blood that leaves the heart in a given time period (i.e. liters per minute), is proportional to ...
Mechanisms of Cardiac Arrhythmias and Conduction Disturbances. In V. Fuster, R.A. Walsh, R.A. Harrington (Eds). ... Cardiovascular Physiology & Anesthesia. Morgan, Jr. GE, Mikhail MS, Murray MJ. Chapter 19. Clinical Anesthesiology. 4th ed. New ... AV reentrant tachycardia AV nodal reentrant tachycardia "Cardiac Arrhythmias". Retrieved 2007-07-21. Am J Cardiol. 1984 Jul 30; ... or bradycardia are potential causes of functionally defined re-entry due to changes in the properties of the cardiac tissue's ...
Cardiac troponin I, TNNI3 (19q13.4, 191044) Cardiac troponin I, often denoted as cTnI, is presented in cardiac muscle tissue by ... Cardiovascular Research. 66: 12-21. doi:10.1016/j.cardiores.2004.12.022. Labugger R, Organ L, Collier C, Atar D, Van Eyk JE ( ... Mannu GS, The non-cardiac use and significance of cardiac troponins. Scott Med J, 2014. 59(3): p. 172-8. Tanindi, Asil; Cemri, ... For more than 15 years cTnI has been known as a reliable marker of cardiac muscle tissue injury. It is considered to be more ...
Cardiac resident macrophages participate in electrical conduction via gap junction communication with cardiac myocytes. ... Cardiovascular Research. 102 (2): 240-248. doi:10.1093/cvr/cvu025. ISSN 1755-3245. PMC 3989449 . PMID 24501331. Sebastiaan Bol ... Frantz, Stefan; Nahrendorf, Matthias (2014-05-01). "Cardiac macrophages and their role in ischaemic heart disease". ...
Seth is the first Asian to be elected to the Board of Governors of Society of the Cardiac Angiographies and Intervention (USA ... He is a trustee of Indo-French Cardiovascular Foundation for Research, Education and Training in the field of Angioplasty and a ... He is a founding member of Endovascular Intervention Society of India, Academy of TCT, New York and the SAARC Cardiac Society ... "Society of the Cardiac Angiographies and Intervention". 2015. Retrieved 3 February 2015. "NTMLI". Times of India. 2015. ...
Daig Corporation manufactured cardiac catheters for diagnostic and therapeutic uses. Also in January of that year, St. Jude ... "3D Cardiovascular Navigation System: Accuracy and Reduction in Radiation Exposure in Left Ventricular Lead Implant". Journal of ... The wireless monitoring technology is used to assess cardiac performance via measurement of PAP and can be placed into the ... Jude Medical's Ilumien Optis 3-D PCI Optimization System Approved in Europe". Cardiac Interventions Today. Retrieved 20 March ...
Jones E, Eteiba W, Merz NB (August 2012). "Cardiac syndrome X and microvascular coronary dysfunction". Trends in Cardiovascular ... and sudden cardiac death. It is within the group of cardiovascular diseases of which it is the most common type. A common ... Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic ... Cardiac syndrome X is chest pain (angina pectoris) and chest discomfort in people who do not show signs of blockages in the ...
Franco D, Campione M (May 2003). "The role of Pitx2 during cardiac development. Linking left-right signaling and congenital ... heart diseases". Trends in Cardiovascular Medicine. 13 (4): 157-63. doi:10.1016/S1050-1738(03)00039-2. PMID 12732450. Hjalt TA ...
New Developments in Cardiac Pacing and Electrophysiology. Armonk (NY): Futura, p. 1-8. ISBN 0879937068 "Cardiovascular Research ... Charles Antzelevitch is an American cardiovascular research scientist internationally known for his work in cardiac ... With cardiac researcher Gan-Xin Yan, MD, PhD, Antzelevitch used coronary-perfused wedge preparation technology to develop a ... Antzelevitch C (1977). Cardiac Actions of Quinidine (Thesis). Syracuse (NY): State University of New York Upstate Medical ...
"Thoratec Acquires Apica Cardiovascular". PR Newswire. July 2, 2014. "Thoratec Acquires Apica Cardiovascular". Cardiac ... "VAD Therapies for Wide Range of Cardiac Conditions". Cardiovascular Center Update, Spring 2007. Brigham and Women's Hospital. ... acute cardiac axial-flow pump that can be delivered percutaneously in a cardiac catheterization lab or operating room. In ... "Thoratec acquires DuraHeart II ventricular assist system". Cardiovascular News. July 15, 2013. "Thoratec Acquires DuraHeart II ...
Neer, EJ; Clapham, DE (Jan-Feb 1992). "Signal transduction through G proteins in the cardiac myocyte". Trends in Cardiovascular ... Chloride channel activity in epethelial and cardiac cells has been found to be G protein-dependent. However, the cardiac ... Altered cardiac regulation is common in adults diagnosed with Down syndrome and may be related to G protein-gated ion channels ... Patch clamp measurements suggest a direct role for Gα in the inhibition of fast Na+ current within cardiac cells. Other studies ...
doi:10.1016/0002-9149(82)90016-9. Polte, CL; Burck, I; Gjertsson, P; Lomsky, M; Nekolla, SG; Nagel, E (2016). "Cardiac Positron ... Emission Tomography: a Clinical Perspective". Current Cardiovascular Imaging Reports. 9 (3). doi:10.1007/s12410-016-9371-3. ...
"Cardiac sarcoidosis-state of the art review". Cardiovascular Diagnosis and Therapy. 6 (1): 50-63. doi:10.3978/j.issn.2223- ... Cardiac MRI and transvenous endomyocardial biopsy may also be necessary in some cases. Reduced QRS voltage on EKG may be an ... The highest incidence of death caused by cardiac sarcoidosis is found in Japan. Hancock, EW (September 2001). "Differential ... Pollak, A; Falk, R H (1993-08-01). "Left ventricular systolic dysfunction precipitated by verapamil in cardiac amyloidosis". ...
Hop regulation of cardiac gene expression". Trends in Cardiovascular Medicine. 13 (7): 261-4. doi:10.1016/S1050-1738(03)00107-5 ... and modulate SRF-dependent cardiac-specific gene expression and cardiac development. Multiple alternatively spliced transcript ... "Cardiac hypertrophy and histone deacetylase-dependent transcriptional repression mediated by the atypical homeodomain protein ... "Hop is an unusual homeobox gene that modulates cardiac development". Cell. 110 (6): 713-23. doi:10.1016/S0092-8674(02)00932-7. ...
Cardiovascular Journal of Africa. 18 (3): 146-53. PMC 4213759 . PMID 17612745. "Entrez Gene: TNNT2 troponin T type 2 (cardiac ... "Troponin T, cardiac muscle". Cardiac Organellar Protein Atlas Database. Zong NC, Li H, Li H, Lam MP, Jimenez RC, Kim CS, Deng N ... Cardiac muscle troponin T (cTnT), is a protein which in humans is encoded by the TNNT2 gene. Cardiac TnT is the tropomyosin- ... Cardiac TnT is a 35.9 kDa protein composed of 298 amino acids. Cardiac TnT is the largest of the three troponin subunits (cTnT ...
The nuclear envelope in muscular dystrophy and cardiovascular diseases. Traffic. 2002, 2 (10): 675-83. PMID 11576443. doi: ... ventricular cardiac muscle cell development. · cellular response to hypoxia. · positive regulation of cell aging. ... The A-type lamins: nuclear structural proteins as a focus for muscular dystrophy and cardiovascular diseases. Trends Cardiovasc ...
Advanced Cardiovascular Life Support (ACLS) Recertification Course is organized by Critical Care Training Center (CCTC) and ... Recognition and early management of respiratory and cardiac arrest. • Recognition and early management of peri-arrest ... Advanced Cardiovascular Life Support (ACLS) Recertification Course (Oct 10, 2020). Oct 10, 2020 , North Hollywood, California ... Advanced Cardiovascular Life Support (ACLS) Recertification Course is organized by Critical Care Training Center (CCTC) and ...
The heart-lung machine is used during these operations, in which one, two, or even three cardiac valves may be removed and ... Repair of acquired cardiac defects: Destroyed heart valves can be replaced with artificial valves (prostheses) made of ... Greatbatch, Wilson: implantable cardiac pacemakerLearn about Wilson Greatbatch and his invention of an implantable cardiac ... Repair of acquired cardiac defects. Valvular disease. Destroyed heart valves can be replaced with artificial valves (prostheses ...
I understand that participation in cardiac rehab programs is low. From a patients perspective, why do you or do you not attend ... I understand that participation in cardiac rehab programs is low.. From a patients perspective, why do you or do you not ...
A method and apparatus for treating congestive heart disease and related cardiac complications such as valvular disorders and ... Extra cardiac ventricular assist device. 1998-02-03. Rosenberg et al.. 5702343. Cardiac reinforcement device. 1997-12-30. ... Cardiac assist method and apparatus. 1995-07-04. Chiu. 5385156. Diagnostic and treatment method for cardiac rupture and ... 30, 1998 describes a cardiac pouch with an elastic limit. A cardiac constraint device can be placed on an enlarged heart and ...
It talks about Angina and Cardiac Syndrome X...Let me know if you ... ... Teri I have recently been diagnosed with Cardiac X syndrome. We are still in the process of finding out what meds will work. I ... HeyTeri I do believe I read rom one of my many dischage summaries thatmy cardio said I had Cardiac Syndrome --do youthink that ... I have all the classic test results, abnormal EKG, abnormal cardiolyte stress test and normal cardiac cath. My question is this ...
The cardiovascular laboratory/cardiac catheterization laboratory is the subspecialty area of cardiology care where invasive ... Cardiac Catheterization Laboratory. The cardiovascular laboratory/cardiac catheterization laboratory is the subspecialty area ... Both cardiac and vascular procedures are performed in the laboratory using state-of-the-art digital imaging with intravascular ... For scheduling and more information, visit Froedtert Hospitals Cardiac Catheterization Laboratory page. ...
Overview of the LifeBridge Health Cardiovascular Institute. Locations. LifeBridge Health Anticoagulation Clinics Cardiac ... Benjamin and Margaret Schapiro Cardiac Diagnostic Center. Emergency Chest Pain Center. Beverly and Jerome Fine Cardiac Valve ... Cardiovascular Institute at LifeBridge Health. 2401 W. Belvedere Ave.. Baltimore, MD 21215. Contact Us: 410-601-9000. ...
Disclosed is a high-frequency intra-arterial cardiac support system having a balloon pump which may be positioned in a major ... 7. A high-frequency intra-arterial cardiac support system according to claim 5 in which said fluid flow to said lumen is a flow ... 1 is a schematic view of the high-frequency intra-arterial cardiac support system in its mode of employment in support of the ... 3 is a schematic view of the high-frequency intra-arterial cardiac support system in its mode of employment in support of the ...
Cardiac Arrest While Walking in the Park. Andrew R. Blum, MD, Robert Altman, MD, Brian Ghoshhajra, MD,. Suhny Abbara, MD, ... Cardiac CTA was useful in excluding coronary anomalies or cardiomyopathies, and led to the surprising diagnosis of premature ... A 49 year-old woman with a history of anorexia and borderline hypertension suffered a cardiac arrest while walking. She was ... Upon admission to Massachusetts General Hospital, her cardiac troponin T was noted to be mildly elevated (0.95 ng/ml), although ...
Cardiac lipids and their role in the diseased heart Ismena Mardani Göteborgs universitet, Doctoral thesis 2019 Doctoral thesis ... Cardiac abnormalities in chronic kidney disease Pavlos Kashioulis Göteborgs universitet, Doctoral thesis 2019 Doctoral thesis ... Antihypertensive drug classes and the risk of hip fracture: results from the Swedish primary care cardiovascular database. Tove ... Early post-transplant elevated pulmonary artery pressure predicts adverse outcome in cardiac recipients. Entela Bollano, Bert ...
Synapse Cardiovascular offers cardiac cath labs intuitive reporting and image management tools to help boost productivity and ... To find out more about Synapse Cardiovasculars cardiac catheterization capabilities, visit the Synapse Cardiovascular website. ... Fully integrated with third-party hemodynamic monitoring systems, Synapse Cardiovascular provides cardiac catheterization ... Create detailed procedural reports in record time with Synapse Cardiovasculars diagram-driven graphical interfaces. Templates ...
Cardiac conduction disturbances in patients with ankylosing spondylitis: results from a 5-year follow-up cohort study. Karin ... Antihypertensive drug classes and the risk of hip fracture: results from the Swedish primary care cardiovascular database. Tove ... Early post-transplant elevated pulmonary artery pressure predicts adverse outcome in cardiac recipients. Entela Bollano, Bert ... Survival, cardiovascular morbidity, and reinterventions after elective endovascular aortic aneurysm repair in patients with and ...
Myocardial infarction: cardiac rehabilitation and prevention of further cardiovascular disease. Number. CG172. Date issued. ... Early cardiac rehabilitation (defined as attendance at a cardiac rehabilitation orientation appointment within 10 days) ... Participation in cardiac rehabilitation after an acute MI significantly reduces mortality and improves quality of life. However ... Why this is important:- There is wide variation across the UK in style, staffing and resources of cardiac rehabilitation ...
... is Board Certified in Cardiac Vascular Nursing and Certified in Adult Critical ... New York Cardiovascular Associates is excited to welcome two new cardiac specialists to its team of providers. Joyce Yeung, RN ... New York Cardiovascular Associates welcomes two new cardiac experts to its team of heart specialists. ... is Board Certified in Cardiac Vascular Nursing and Certified in Adult Critical Care and Cardiac Surgery Subspecialty. She ...
... a review of studies out of China shows that COVID-19 can cause death in people with underlying cardiovascular disease and cause ... cardiac injury even in those with no history of heart problems. ... Cardiac tamponade can be fatal if it isnt promptly diagnosed ... COVID-19 linked to cardiac ailments in those with, without cardiovascular disease. By Brian P. Dunleavy ... of studies in China highlights that COVID-19 can cause death in people with underlying cardiovascular disease and cause cardiac ...
John Spratt, MD is a cardiac surgery doctor who practices in Charleston, SC. He is 63 years old and has been practicing for 65 ... including a cardiac surgeon, to be at intermediate or greater risk for open surgical therapy (i.e., predicted risk of surgical ... including a cardiac surgeon, to be at high or greater risk for open surgical therapy (i.e., predicted risk of surgical ...
Among cardiac interstitial cells, the recently described telocytes (TCs) display the unique ability to build a supportive three ... Cardiac stromal cells Cardiovascular diseases Exosomes Extracellular vesicles Telocytes This is a preview of subscription ... Finally, the involvement of cardiac TCs in cardiovascular diseases and the potential utility of TC transplantation and TC- ... Popescu LM, Fertig ET, Gherghiceanu M (2016) Reaching out: junctions between cardiac telocytes and cardiac stem cells in ...
1) and his presenting cardiac enzymes were elevated (troponin 1.78 and CK-MB 65). A cardiac ultrasound (ECHO) demonstrated a ... Young Man with Chest Pain and Positive Cardiac Enzymes. Leon Shturman, MD, Amar Shah, MD, Erick Avelar, MD, Kathlyn Lam, MD, ... Cardiac magnetic resonance (CMR) revealed increased T2 signal of the sub-epicardial myocardium, predominantly affecting the ... Diagnostic performance of cardiovascular magnetic resonance in patients with suspected acute myocarditis: comparison of ...
... cvi42 is a vendor independent cardiovascular post-processing software comprised of state-of-the-art modules for ... Olea Medical® and Circle Cardiovascular Imaging Inc. Partner to Provide Expanded Cardiac MR Post-Processing Capabilities. ... Circle Cardiovascular Imaging Inc. develops analytics software for the evaluation of cardiovascular MR and CT images. Circle ... a provider of analytical software for cardiac imaging, partner to provide access to cardiac MR post-processing via OleaSphereTM ...
This guideline covers cardiac rehabilitation and preventing further cardiovascular disease in people aged 18 and over who have ... Myocardial infarction: cardiac rehabilitation and prevention of further cardiovascular disease. Clinical guideline [CG172]. ... This guideline covers cardiac rehabilitation and preventing further cardiovascular disease in people aged 18 and over who have ... cardiac rehabilitation and prevention of further cardiovascular disease (CG172) and myocardial infarction with ST-segment ...
Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises. Part I: Aging Arteries: A "Set Up" for ... Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises. Part III: cellular and molecular clues to ... Lakatta EG, Levy D. Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises. Part II: the aging ... C, Common carotid intimal medial thickness predicts future cardiovascular events in Cardiovascular Health Study (CHS). D, ...
Cardiac Consult Protocols Cardiology Fellows on the General Consult Service are expected to follow these protocols:. Consults. ... The Cardiology Fellow assigned to the Consult Service may choose to perform the cardiac catheterizations on patients who he/she ... After hours, the consult resident should contact the Cardiology Fellow assigned to the UAB cardiac catheterization laboratory ... The Cardiology Fellow assigned to the consult service is responsible for scheduling cardiac catheterization procedures on ...
This item: The Nuts and Bolts of Cardiac Resynchronization Therapy. Implantable Cardiac Pacemakers and Defibrillators: All You ... Builds on Tom Kennys previous two books, The Nuts and Bolts of Cardiac Pacing (June 2005) and The Nuts and Bolts of ICD ... Thomas P. Kenny, author of The Nuts & Bolts of Cardiac Pacing and The Nuts and Bolts of ICDs, is the author on this book. In ... The Nuts and Bolts of Cardiac Resynchronization Therapy. By Tom Kenny, RN. Vice President, Clinical Education and Training, St ...
ArrestCardiologyOutcomesMortalityMagneticDiagnosisSudden deathMyocardial infarctionPhase of the cardiac cycleAngiography20172018HeartArrhythmiaLaboratoryDiagnosticPreventionCardiologistsResynchronization Therapy DefibrillatorInvasiveSouth Nassau's CenterMethodsBiomarkersNoninvasive cardiacPostoperative cardiacCenter for Cardiovascular HealthEvaluationHypertensionHiPSC derivedRiskHealth
- ACLS is designed for healthcare professionals who either direct or participate in the management of cardiopulmonary arrest and other cardiovascular emergencies. (emedevents.com)
- Additional important areas of emphasis include the proper management of situations likely to lead to cardiac arrest and the stabilization of the patient in the early period following a successful resuscitation. (asante.org)
- Recognize and initiate early management of peri-* arrest conditions that may result in cardiac arrest or complicate resuscitation outcome. (asante.org)
- Manage cardiac arrest until return of spontaneous circulation, termination of resuscitation, or transfer of care. (asante.org)
- The cardiovascular laboratory/cardiac catheterization laboratory is the subspecialty area of cardiology care where invasive procedures are performed. (mcw.edu)
- The Cardiology Fellow assigned to the consult service is responsible for scheduling cardiac catheterization procedures on consult patients between 8 AM and 5 PM. After hours, the consult resident should contact the Cardiology Fellow assigned to the UAB cardiac catheterization laboratory to add the patient to the schedule. (uab.edu)
- The Cardiology Fellow assigned to the Consult Service may choose to perform the cardiac catheterizations on patients who he/she has previously evaluated, provided that the procedure does not interfere with consult rounds or duties at CGH. (uab.edu)
- The Sam & Anne Kesner Heart Center at Methodist Dallas offers some of the most advanced cardiac care and cardiology services available in the Dallas-Fort Worth Metroplex. (methodisthealthsystem.org)
- Two of these labs are devoted to cardiac catheterization and interventional cardiology. (methodisthealthsystem.org)
- With the support of Cardiovascular 2016 Organizing Committee Members, we have scheduled 2nd International Conference on Cardiovascular Medicine to be held at London, UK during March 15-16, 2017 .This International Cardiology Conference will bring together world-class cardiovascular researchers, cardiologists, cardiovascular surgeons , professors and scientists to discuss strategies for Cardiology. (ctsnet.org)
- Relation of cardiac troponin I levels with in-hospital mortality in patients with ischemic stroke, intracerebral hemorrhage, and subarachnoid hemorrhage," American Journal of Cardiology , vol. 102, no. 5, pp. 632-634, 2008. (hindawi.com)
- For patients without ST-segment elevation, urgent cardiology consultation is appropriate, with cardiac catheterization for those patients with dynamic ST-segment shifts, ongoing ischemia, and/or cardiogenic shock (3-5) . (onlinejacc.org)
- The Advanced Cardiovascular Imaging Fellowship at UC San Diego Medical Centers is a 12 month multi-modality fellowship training opportunity encompassing cardiovascular MRI and CT, echocardiography, and nuclear cardiology. (scct.org)
- The Multimodality Cardiac Imaging fellowship at Cedars-Sinai provides a comprehensive clinical and research program in cardiac CT, nuclear cardiology, and cardiac MRI. (scct.org)
- He completed his cardiology fellowship training at the University of California, Los Angeles, and upon completion of his training joined the faculty at University of Iowa, where he also served as the Associate Director of Cardiac Electrophysiology. (uclahealth.org)
- The report provides value, in millions of US dollars and volume (in units) within market categories - Cardiac Assist Devices, Cardiac Rhythm Management Devices, Cardiovascular Prosthetic Devices, Cardiovascular Surgery Devices, Clot Management Devices, Electrophysiology Devices, External Defibrillators, Interventional Cardiology, Peripheral Vascular Devices and Prosthetic Heart Valves. (researchandmarkets.com)
- Market size for Cardiovascular Device market categories - Cardiac Assist Devices, Cardiac Rhythm Management Devices, Cardiovascular Prosthetic Devices, Cardiovascular Surgery Devices, Clot Management Devices, Electrophysiology Devices, External Defibrillators, Interventional Cardiology, Peripheral Vascular Devices and Prosthetic Heart Valves. (marketresearch.com)
- However, with 80 percent of cardiology conditions being lifestyle-related, cardiac rehab addresses those underlying lifestyle components such as nutrition and exercise to really impact a patient's long-term health. (howell.org)
- Smith- who tested the program by applying it himself, losing 40 pounds and improving his own health- says cardiac rehab can reduce the risk of dying or having another heart attack by as much as 30 to 50 percent, according to the American College of Cardiology, which is as good or better as medication with fewer side effects. (howell.org)
- The database is endorsed by Association of Cardiovascular Interventions of the Polish Cardiac Society (AISN PTK) and is operated by the Jagiellonian University Medical College, with currently 153 interventional cardiology centers in Poland reporting daily. (termedia.pl)
- Mullins worked to advance interventional cardiology, using cardiac catheterization to repair heart defects. (wikipedia.org)
- The American Academy of Pediatrics Section on Cardiology and Cardiac Surgery gave Mullins its Founders Award in 2004. (wikipedia.org)
- Although remarkable progress has been made in the treatment of ST-segment elevation myocardial infarction, out-of-hospital cardiac arrest (OHCA) continues to be a major challenge with significant regional variability in management and outcomes across the United States and the world (1-4) . (onlinejacc.org)
- Conclusions Metformin is associated with beneficial cardiovascular outcomes in patients with diabetes only when (sub)clinical cardiovascular risk defined by NT-proBNP levels is present. (bmj.com)
- To improve health outcomes through effective use of cardiovascular CT. (scct.org)
- Colorado Cardiovascular Outcomes Research Group, Denver (P.D.V. (ahajournals.org)
- Baseline heart rate, antihypertensive treatment, and prevention of cardiovascular outcomes in ASCOT (Anglo-Scandinavian Cardiac Outcomes Trial). (sigmaaldrich.com)
- The goal of our Center for Cardiovascular Health is to bring you and your family the following: outstanding treatment, outstanding outcomes, outstanding care. (southnassau.org)
- The 72-session intensive cardiac rehab enhances conventional 36-session cardiac rehab, enabling a more comprehensive series of exercise, nutrition and stress management sessions for improved outcomes. (howell.org)
- This is a parallel arm, multi-centre, randomised controlled trial that will assess the outcomes of post- phase 2 cardiac rehabilitation patients assigned to a yoga intervention in comparison to a no-treatment wait-list control group. (biomedcentral.com)
- Secondary outcomes include measures of quality of life, and cardiovascular and cognitive function. (biomedcentral.com)
- The cardiovascular outcomes will include blood pressure, heart rate, heart rate variability, pulse wave velocity, carotid intima media thickness measurements, lipid/glucose profiles and C-reactive protein assays. (biomedcentral.com)
- Public reporting of the high mortality, such as patients with cardiac arrest undergoing percutaneous coronary intervention, complicates the issue even further. (onlinejacc.org)
- Trials that assessed whether amiodarone prophylaxis decreases the incidence of postoperative atrial tachyarrhythmias have had mixed results and were not specifically powered to detect changes in cardiovascular morbidity, length of stay, or mortality. (annals.org)
- Risks of sudden cardiac death (SCD), cardiovascular death and all-cause mortality according to RASI treatment were analyzed by multivariable time-varying Cox models and propensity score matched analyses. (diva-portal.org)
- Conclusions: RASI was not associated with SCD, cardiovascular or all-cause mortality in asymptomatic AS patients. (diva-portal.org)
- The association of CR with all-cause mortality, cardiac mortality, myocardial infarction, or revascularization was assessed with 3 statistical techniques: propensity score-matched analysis (n=1438), propensity score stratification (n=2351), and regression adjustment with propensity score in a 3-month landmark analysis (n=2009). (ovid.com)
- Various metrics and subspaces are extracted to characterize the risk for serious heart rhythm disturbances, sudden cardiac death, other modes of death, and all-cause mortality linked to different electrical abnormalities of the heart. (patents.com)
- Cardiac magnetic resonance (CMR) revealed increased T2 signal of the sub-epicardial myocardium, predominantly affecting the inferior-lateral wall (Fig. 2). (massgeneral.org)
- Diagnostic performance of cardiovascular magnetic resonance in patients with suspected acute myocarditis: comparison of different approaches. (massgeneral.org)
- Delayed enhancement and T2-weighted cardiovascular magnetic resonance imaging differentiate acute from chronic myocardial infarction. (massgeneral.org)
- 2 Cardiovascular Magnetic Resonance: Basic Principles, Methods, and Techniques ( Joseph Selvanayagam, Matthew Robson, Jane Francis & Stefan Neubauer ). (wiley.com)
- 8 Cardiovascular Magnetic Resonance: Evaluation of Myocardial Function, Perfusion, and Viability ( Padmini Varadarajan, Ramdas G. Pai, Krishna S. Nayak, Hee-Won Kim & Gerald M. Pohost ). (wiley.com)
- 11 Cardiac Computed Tomography and Magnetic Resonance for the Evaluation of Acute Chest Pain in the Emergency Department ( Eric M. Thorn & Charles S. White ). (wiley.com)
- Objective To evaluate cardiac involvement in patients with ankylosing spondylitis using cardiac magnetic resonance (CMR). (bmj.com)
- Cardiovascular magnetic resonance and prognosis in cardiac amyloidosis. (scmr.org)
- Cardiovascular magnetic resonance is a versatile tool that enables noninvasive characterization of cardiac tissue structure and function. (onlinejacc.org)
- The cardiac magnetic resonance fingerprinting (cMRF) technique has recently been introduced for simultaneous and reproducible measurement of T 1 and T 2 maps in a single scan. (onlinejacc.org)
- Cardiovascular magnetic resonance is a valuable and versatile tool to characterize myocardial tissue and assess cardiac function noninvasively. (onlinejacc.org)
- 1. Cardiac magnetic resonance imaging in systemic sclerosis: a cross-sectional observational study of 52 patients. (scmr.org)
- Cardiovascular Magnetic Resonance (CMR) enables non-invasive quantification of cardiac output (CO) and thereby cardiac index (CI, CO indexed to body surface area). (nih.gov)
- Objectives This study analyzed the accuracy of gadolinium-enhanced cardiovascular magnetic resonance (CMR) for the diagnosis of cardiac sarcoidosis (CS). (onlinejacc.org)
- Cardiovascular magnetic resonance, echocardiography images, and circulating levels of biomarkers were obtained before and after anthracycline treatment. (ahajournals.org)
- The Society for Cardiovascular Magnetic Resonance (SCMR) is an international non-profit medical society based in Mt. Royal, New Jersey, in the United States. (wikipedia.org)
- citation needed] It was established as international representative and advocate for physicians, scientists, and technologists working in cardiovascular magnetic resonance (CMR) imaging. (wikipedia.org)
- Recipients have been: The society publishes an open access journal, the Journal of Cardiovascular Magnetic Resonance. (wikipedia.org)
- The society also provides online introductory training in Cardiovascular Magnetic Resonance. (wikipedia.org)
- Atlas of Practical Applications of Cardiovascular Magnetic Resonance. (wikipedia.org)
- As soon as our cardiac testing is complete and a diagnosis is made, our team of specially-trained cardiologists, interventional radiologists, surgeons, nurses and technologists work together to provide patients with the best solution. (dekalbmedical.org)
- The diagnosis of cardiac sarcoidosis (CS) is made in the co-existence of non-caseating granulomas on myocardial biopsy and/or biopsies of any extracardiac tissue (with the exclusion of other causes of granulomatous inflammation such as mycobacterial or fungal infection) and cardiovascular abnormalities for which other possible causes have been excluded. (onlinejacc.org)
- Data suggests that also SARS may have resulted in cardiovascular complications, such as acute coronary syndrome and myocardial infarction, in some of those infected. (upi.com)
- ACE is not only an important diagnostic parameter for sarcoidosis and myocardial infarction but is also an important parameter for determining general cardiovascular health. (bio-medicine.org)
- Key secondary endpoint(s) are routine (Local laboratory) dosage of standard cardiac Troponin I (cTnI) at D1 (24h) and D3 (72 h) post operatively, and also in case of any suspicion of Myocardial Infarction , Routine cardiac safety monitoring. (bioportfolio.com)
- Cardiac repair in a porcine model of acute myocardial infarction with human induced pluripotent stem cell-derived cardiovascular cells. (biomedsearch.com)
- Based on the application type, th e temporary cardiac pacing wires & leads market is segmented into cardiothoracic surgeries, acute myocardial infarction, bradycardia, heart blocks, congestive heart failure (CHF), and sick sinus syndrome. (pharmiweb.com)
- The pericardium becomes thickened and fibrotic, and over a period of time it constricts the heart so that the normal filling of the ventricles during the resting phase of the cardiac cycle is limited. (britannica.com)
- These are important for allowing time for certain chambers to fill and empty depending on the phase of the cardiac cycle. (coursera.org)
- The clinician focuses attention sequentially on each phase of the cardiac cycle, noting each heart sound and murmur. (merckmanuals.com)
- Our experienced and subspecialised Radiologists (with Level II Accreditation by the Conjoint Committee for the Recognition of Training in CT Coronary Angiography) and CT Radiographers have been pioneers and industry leaders in the field of Cardiac CT in Australia. (sah.org.au)
- Although a very low likelihood of neurologic recovery has traditionally been a factor dissuading against early angiography, it is now recognized that it is generally extremely difficult to determine who has very low likelihood of recovery in the early hours following cardiac arrest (2-4) . (onlinejacc.org)
- Caring for Yourself after Cardiac Catheterization/Arterial Angiography Femoral Artery or Femoral Artery Closure Device Your cardiac catheterization on _______________________________ was through the RIGHT / LEFT femoral artery. (uwhealth.org)
- This course will review several noninvasive cardiac tests, including the ECG, exercise stress test, pharmacological stress test, nuclear scans, CT calcium scan, CT angiography and cardiac MRI with an emphasis on patient preparation and nursing care. (continuingeducation.com)
- Cardiac evaluation and management intensity, the main outcome measure, was measured at the individual level, and consisted of receiving one or more of the following services: noninvasive cardiac testing, coronary angiography and statin use (the latter among individuals 65 years of age and older). (ices.on.ca)
- The methodology for use of cardiac CT angiography (CTA) in low risk populations is not well defined. (nih.gov)
- A recent market study "Temporary Cardiac Pacing Wires & Leads Market: Global Industry Analysis 2013 - 2017 and Forecast 2018 - 2026" consists of a comprehensive assessment of the most important market dynamics.On conducting a thorough research on the historic as well as current growth parameters of the temporary cardiac pacing wires & leads market, growth prospects of the market are obtained with maximum precision. (pharmiweb.com)
- The heart-lung machine is used during these operations, in which one, two, or even three cardiac valves may be removed and replaced with the appropriate artificial valve . (britannica.com)
- Treatment is the surgical removal of the thickened pericardium around the heart, which permits normal filling and expansion of the ventricles and restores adequate cardiac output to the vital organs. (britannica.com)
- Greetings, today we want to continue our discussion of the cardiovascular system, In particular we want to think about how the heart adjust its output of blood to match the needs of the body in general. (coursera.org)
- In terms of venous return, that is the blood coming back into the heart and its filling versus cardiac output. (coursera.org)
- As you know from the last time when we met, the cardiac output is equal to stroke volume times heart rate. (coursera.org)
- An individual who has a heart rate of 50 milliliters per minute, beats per minute, and has a cardiac output of 5 liters per minute will then have a stroke volume of 100 milliliters. (coursera.org)
- Disclosed is a high-frequency intra-arterial cardiac support system having a balloon pump which may be positioned in a major artery downstream of a natural heart. (freepatentsonline.com)
- 8. A high-frequency intra-arterial cardiac support system according to claim 5 in which said valve is a collapsible one-way passive check valve oriented to direct blood flow predominantly in the direction of normal blood flow away from the natural heart. (freepatentsonline.com)
- NYCVA's Dr. Han Hwang and Joyce Yeung - the newest cardiac experts to join the team of heart specialists. (prweb.com)
- Cardiac TCs are increasingly regarded as pivotal regulators in intercellular signaling with multiple cell types, such as cardiomyocytes, stem/progenitor cells, microvessels, nerve endings, fibroblasts and immune cells, thus converting the cardiac stromal compartment into an integrated system that may drive either heart development or maintenance of cardiac homeostasis in post-natal life. (springer.com)
- Cardiac resynchronization therapy (CRT) is an exciting new option for a growing number of heart failure patients, but CRT systems present special challenges to clinicians, even those accustomed to working with pacemakers. (wiley.com)
- The Nuts and Bolts of Cardiac Resynchronization Therapy concentrates on the practical aspects of how these devices work and how to follow the growing number of patients who are using them to fight heart failure. (wiley.com)
- 2 Cardiovascular Anatomy of the Healthy Heart. (wiley.com)
- 3 Cardiac Physiology and Heart Failure. (wiley.com)
- Having this single, centralized heart care center for all cardiac diagnostic tests and heart treatments can mean less travel for our patients and their family members--just one of the ways we're committed to taking care of our community. (methodisthealthsystem.org)
- Cardiac catheterization works by inserting a catheter through blood vessels into the heart. (sharecare.com)
- During cardiac catheterization your doctor can take pictures of the insides of your arteries or extract a small tissue sample from the heart for further examination. (sharecare.com)
- Cardiac catheterization involves the insertion of small tubes into a chamber or vessel of the heart under X-ray guidance to detect obstructions or malformations. (sharecare.com)
- It may also be called cardiac cath, heart cath or an angiogram. (sharecare.com)
- Cardiac catheterization is a common non-surgical procedure used to help diagnose a heart problem. (sharecare.com)
- A cardiac catheterization (cath) is a procedure that passes a catheter in a blood vessel via veins in the groin or arm and then guided to the heart. (sharecare.com)
- Cardiac catheterization is a diagnostic test used to detect heart disorders. (sharecare.com)
- During the cardiac catheterization, fluoroscopic images are viewed and recorded and heart and great vessel pressures are measured. (sharecare.com)
- A cardiac cathterization is a common invasive heart procedure to diagnose blockages in the arteries, abnormalities of the heart muscle or valves and to measure blood pressure inside the heart or lung. (sharecare.com)
- S1 and the 2nd heart sound (S2, a diastolic heart sound) are normal components of the cardiac cycle, the familiar "lub-dub" sounds. (merckmanuals.com)
- After exclusion of 57 patients who underwent SPECT-driven PCI or CABG, 318 patients were tracked and showed a 15.7% rate of cardiac death-including sudden cardiac death, fatal MI, or death from heart failure-over a mean follow-up of 3.6 years. (cardiovascularbusiness.com)
- In the WISE study of 936 women undergoing cardiac catheterization for chest pain, 60% did not have a major blockages in the arteries of their heart. (simstat.com)
- OBJECTIVE On 10/11/08, the Cleveland Clinic Heart and Vascular Institute (HVI) initiated a dedicated "Cardiac Medical Emergency Team" (CMET) for all cardiovascular patients requiring emergency cardiac care (ECC) including urgent medical evaluation and resuscitation for cardiopulmonary arrest (CPA) or acute respiratory compromise (ARC). (ahajournals.org)
- The comprehensive review article focuses on traditional cardiac biomarkers as well as novel emerging cardiac-specific biomarkers, such as cardiac troponins, natriuretic peptides, heart-type fatty acid-binding protein, and miRNAs. (medicalxpress.com)
- Heart rate is an established risk factor for cardiovascular events. (sigmaaldrich.com)
- Primary analyses used Cox models to investigate the potential attenuation of the treatment effect with higher baseline heart rate on total cardiovascular events and procedures (TCVP) via introduction of an interaction term. (sigmaaldrich.com)
- Our lab has studied how these cardiac progenitors evolve in the developing heart and applied our finding to iPSCs to recapitulate the cardiac progenitors to ultimately use in clinical therapies. (ca.gov)
- The SIMULIA Living Heart Human Model provides a unique testing environment where a stent can be deployed virtually in coronary arteries and deformed mechanically during the cardiac cycle. (drugdiscoveryonline.com)
- Although several cases of cardiac venous perforation after catheterization in the right heart have been reported, this kind of phenomenon occurring after PCI alone has never been reported. (onlinejacc.org)
- A non-invasive test, performed in our cardiovascular lab, that uses sound waves to provide images of your heart. (dekalbmedical.org)
- Non-invasive cardiac testing that allows cardiologists to view the heart vessels using advanced CT equipment. (dekalbmedical.org)
- This heart assessment, performed in our advanced cardiovascular lab, is the "gold standard" for determining where and to what extent you may have blockages in the arteries that serve your heart. (dekalbmedical.org)
- We specialize in cardiac catheterization, angioplasty, and other advanced tests and treatments related to the heart and blood flow. (southnassau.org)
- To determine whether the reduced baroreceptor-heart rate reflex sensitivity in genetically hypertensive rats is related to the level of cardiac or vascular hypertrophy. (ovid.com)
- In SHR treated from 4 until 12 weeks of age, which prevented cardiac hypertrophy, the vagal heart rate range was markedly greater. (ovid.com)
- Thus the improvement in the vagal heart rate range was more closely related to the prevention of cardiac hypertrophy (r=0.73, P (ovid.com)
- These results suggest that prevention of cardiac rather than vascular hypertrophy is the major requirement for normalizing the vagal component of the baroreceptor-heart rate reflex in hypertensive rats. (ovid.com)
- Methods and systems for evaluating the electrical activity of the heart to identify novel ECG patterns closely linked to the subsequent development of serious heart rhythm disturbances and fatal cardiac events. (patents.com)
- BME 210 Spring 2009 Measuring Cardiac Output 2 Measuring Cardiac Output I. Introduction The volume of blood pumped by the heart in a given period of time is defined as cardiac output. (coursehero.com)
- Next, we will see how we can apply these basic principles (given certain assumptions) to the problem of measuring blood flow from the heart in the intact cardiovascular system. (coursehero.com)
- He is known for advancing cardiac catheterization techniques to treat congenital heart defects. (wikipedia.org)
- Mullins introduced a sheath and introducer system for carrying out cardiac catheterization and he pioneered the use of endovascular stents to treat children with heart defects. (wikipedia.org)
- Interdisciplinary studies at the UAB Cardiac Rhythm Management Lab Laboratory (CRML) involve the interaction and collaboration of investigators in the electrophysiology laboratory and surgical operating room. (uab.edu)
- The Core Laboratory also provides turnkey implementation and guidance on CMRI acquisition and sequence protocols for multicenter trials that use cardiovascular MRI surrogates as endpoints. (uhhospitals.org)
- To be registry eligible, they must have worked in the Cardiac Catheterization Laboratory for two years or have graduated from a registry eligible program. (wikipedia.org)
- NuView Radiopharmaceuticals has executed an exclusive license agreement with the University of Southern California (USC) that provides NuView with the development and commercialization rights to a tagged derivative of the naturally found biological molecule adenosine, called F-18 FXA, for potential use as a diagnostic cardiac PET radiopharmaceutical in clinical trials. (cardiovascularbusiness.com)
- The diagnostic efficiency and specificity related to cardiac biomarker testing renders it a universally gold standard test to diagnose cardiovascular disorders worldwide. (medgadget.com)
- Description** The Cardiovascular Technologist (CVT) provides technical services and support duties in the areas of invasive diagnostic and interventional cardiovascular and peripheral-vascular procedures performed in the Cardiac Cath Lab for neonatal, pediatric and adult patients. (sacjobs.com)
- Knowledge of invasive cardiac diagnostic and interventional procedures is preferred. (sacjobs.com)
- Conclusions In patients with sarcoidosis, CMR is a useful diagnostic tool to determine cardiac involvement. (onlinejacc.org)
- Methods From the National Cardiovascular Data Registry's Implantable Cardiac-Defibrillator Registry, we defined a cohort of 45,392 cardiac resynchronization therapy-defibrillator (CRT-D) implants between January 2006 and June 2008 with a primary prevention indication. (onlinejacc.org)
- Methods and Results This report encompasses 121 women included in the 2×2 factorial, placebo‐controlled, double‐blind PRADA (Prevention of Cardiac Dysfunction During Adjuvant Breast Cancer Therapy) trial with metoprolol and candesartan given concomitantly with anticancer therapy containing the anthracycline, epirubicin (total cumulative dose, 240-400 mg/m 2 ). (ahajournals.org)
- Candidate is required to be a Registered Cardiovascular Invasive Specialist (RCIS) by Cardiovascular Credentialing International or registry-eligible within 18 months of hire. (sacjobs.com)
- Recent clinical experience/background in the areas of hemodynamic monitoring, ECG interpretation, scrubbing invasive cardiac procedures in an invasive Cath Lab is preferred. (sacjobs.com)
- North America is estimated to dominate the global cardiac biomarkers market. (medgadget.com)
- Cardiovascular biomarkers may reflect myocardial injury, dysfunction, inflammation, and fibrosis and may precede and predict the development of left ventricular impairment. (ahajournals.org)
- The aim of this study was to assess: (1) longitudinal change in circulating cardiovascular biomarkers, (2) the effect of metoprolol succinate and candesartan cilexetil on the biomarker response, and (3) the associations between on‐treatment changes in biomarker concentrations and subsequent left ventricular dysfunction in patients with early breast cancer receiving anthracyclines. (ahajournals.org)
- With a diagram-driven graphical user interface, intuitive report preparation functions and advanced image evaluation tools, Synapse Cardiovascular helps to boost cath lab productivity and accuracy. (fujifilmusa.com)
- Patient care in many settings may include cardiac procedures as part of a thorough patient evaluation. (continuingeducation.com)
- Antihypertensive drug classes and the risk of hip fracture: results from the Swedish primary care cardiovascular database. (gu.se)
- As a result of the research, the authors found that severely impaired myocardial fatty acid metabolism, which might mainly reflect repetitive myocardial ischemia, can identify a high-risk group of cardiac death among hemodialysis patients. (cardiovascularbusiness.com)
- Objectives/Background Based on previous experiences, the Food and Drug Administration and the European Medicines Agency recommend that clinical trials for novel antidiabetic drugs are powered to detect increased cardiovascular risk. (bmj.com)
- The influence of baseline cardiovascular risk on any treatment effect appears obvious but has not been formally proven. (bmj.com)
- We therefore evaluated association of metformin and sulfonylureas with cardiovascular events in patients with different cardiovascular risk profiles indicated by N-terminal of the prohormone brain natriuretic peptide (NT-proBNP) levels. (bmj.com)
- Both are associated with increased cardiovascular risk, and markers that predict this risk more accurately will allow us to target treatment to the subjects most at risk. (medicalxpress.com)
- Soft plaque by CT and cardiac risk factors. (medis.nl)
- The team of David Bluemke et al tied soft plaque on CT using QAngio CT to cardiac risk factors. (medis.nl)
- The Pritikin program has proven to be very successful for patients at high risk for a cardiovascular event, and we are thrilled to bring this program to Livingston county to improve the health and wellness of our local community," said John O' Malley, president of St. Joseph Mercy Livingston hospital. (howell.org)
- Dr. Han Hwang and Ms. Yeung are excited to be part of NYCVA's team of cardiac specialists, and are especially committed to helping women in New York improve their cardiac health. (prweb.com)
- These results underscore the importance of physician service maldistribution and supply-sensitive care on the appropriateness of cardiac health service use. (ices.on.ca)