Lung Neoplasms: Tumors or cancer of the LUNG.Tetranitromethane: Corrosive oxidant, explosive; additive to diesel and rocket fuels; causes skin and lung irritation; proposed war gas. A useful reagent for studying the modification of specific amino acids, particularly tyrosine residues in proteins. Has also been used for studying carbanion formation and for detecting the presence of double bonds in organic compounds.Chloroprene: Toxic, possibly carcinogenic, monomer of neoprene, a synthetic rubber; causes damage to skin, lungs, CNS, kidneys, liver, blood cells and fetuses. Synonym: 2-chlorobutadiene.Flame Retardants: Materials applied to fabrics, bedding, furniture, plastics, etc. to retard their burning; many may leach out and cause allergies or other harm.Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm but is often wrongly used as a synonym for "cancer." (From Dorland, 27th ed)Adenocarcinoma, Bronchiolo-Alveolar: A carcinoma thought to be derived from epithelium of terminal bronchioles, in which the neoplastic tissue extends along the alveolar walls and grows in small masses within the alveoli. Involvement may be uniformly diffuse and massive, or nodular, or lobular. The neoplastic cells are cuboidal or columnar and form papillary structures. Mucin may be demonstrated in some of the cells and in the material in the alveoli, which also includes denuded cells. Metastases in regional lymph nodes, and in even more distant sites, are known to occur, but are infrequent. (From Stedman, 25th ed)Propylene Glycols: Derivatives of propylene glycol (1,2-propanediol). They are used as humectants and solvents in pharmaceutical preparations.Lung: Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.Genes, ras: Family of retrovirus-associated DNA sequences (ras) originally isolated from Harvey (H-ras, Ha-ras, rasH) and Kirsten (K-ras, Ki-ras, rasK) murine sarcoma viruses. Ras genes are widely conserved among animal species and sequences corresponding to both H-ras and K-ras genes have been detected in human, avian, murine, and non-vertebrate genomes. The closely related N-ras gene has been detected in human neuroblastoma and sarcoma cell lines. All genes of the family have a similar exon-intron structure and each encodes a p21 protein.Carcinoma, Squamous Cell: A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.Mice, Inbred Strains: Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations, or by parent x offspring matings carried out with certain restrictions. All animals within an inbred strain trace back to a common ancestor in the twentieth generation.Codon: A set of three nucleotides in a protein coding sequence that specifies individual amino acids or a termination signal (CODON, TERMINATOR). Most codons are universal, but some organisms do not produce the transfer RNAs (RNA, TRANSFER) complementary to all codons. These codons are referred to as unassigned codons (CODONS, NONSENSE).Carcinoma in Situ: A lesion with cytological characteristics associated with invasive carcinoma but the tumor cells are confined to the epithelium of origin, without invasion of the basement membrane.Lung Diseases: Pathological processes involving any part of the LUNG.Carcinoma, Papillary: A malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. (Stedman, 25th ed)Liver Neoplasms: Tumors or cancer of the LIVER.Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents.Carcinoma, Non-Small-Cell Lung: A heterogeneous aggregate of at least three distinct histological types of lung cancer, including SQUAMOUS CELL CARCINOMA; ADENOCARCINOMA; and LARGE CELL CARCINOMA. They are dealt with collectively because of their shared treatment strategy.Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).Carcinoma, Basal Cell: A malignant skin neoplasm that seldom metastasizes but has potentialities for local invasion and destruction. Clinically it is divided into types: nodular, cicatricial, morphaic, and erythematoid (pagetoid). They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck area and the remaining 15% on the trunk and limbs. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1471)Adenocarcinoma: A malignant epithelial tumor with a glandular organization.Carcinoma, Ductal, Breast: An invasive (infiltrating) CARCINOMA of the mammary ductal system (MAMMARY GLANDS) in the human BREAST.Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.Thyroid Neoplasms: Tumors or cancer of the THYROID GLAND.Tumor Markers, Biological: Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.Carcinoma, Small Cell: An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. It is characterized by a dominant, deeply basophilic nucleus, and absent or indistinct nucleoli. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1286-7)Lung Injury: Damage to any compartment of the lung caused by physical, chemical, or biological agents which characteristically elicit inflammatory reaction. These inflammatory reactions can either be acute and dominated by NEUTROPHILS, or chronic and dominated by LYMPHOCYTES and MACROPHAGES.Skin Neoplasms: Tumors or cancer of the SKIN.Neoplasm Staging: Methods which attempt to express in replicable terms the extent of the neoplasm in the patient.Neoplasm Invasiveness: Ability of neoplasms to infiltrate and actively destroy surrounding tissue.Neoplasms, Multiple Primary: Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. The neoplasms may be histologically the same or different, and may be found in the same or different sites.Carcinoma, Bronchogenic: Malignant neoplasm arising from the epithelium of the BRONCHI. It represents a large group of epithelial lung malignancies which can be divided into two clinical groups: SMALL CELL LUNG CANCER and NON-SMALL-CELL LUNG CARCINOMA.Carcinoma, Transitional Cell: A malignant neoplasm derived from TRANSITIONAL EPITHELIAL CELLS, occurring chiefly in the URINARY BLADDER; URETERS; or RENAL PELVIS.Lung Transplantation: The transference of either one or both of the lungs from one human or animal to another.Prognosis: A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.Carcinoma, Adenoid Cystic: Carcinoma characterized by bands or cylinders of hyalinized or mucinous stroma separating or surrounded by nests or cords of small epithelial cells. When the cylinders occur within masses of epithelial cells, they give the tissue a perforated, sievelike, or cribriform appearance. Such tumors occur in the mammary glands, the mucous glands of the upper and lower respiratory tract, and the salivary glands. They are malignant but slow-growing, and tend to spread locally via the nerves. (Dorland, 27th ed)Cell Line, Tumor: A cell line derived from cultured tumor cells.Breast Neoplasms: Tumors or cancer of the human BREAST.Ovarian Neoplasms: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.DNA, Neoplasm: DNA present in neoplastic tissue.Gene Expression Regulation, Neoplastic: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in neoplastic tissue.Carcinoma, Neuroendocrine: A group of carcinomas which share a characteristic morphology, often being composed of clusters and trabecular sheets of round "blue cells", granular chromatin, and an attenuated rim of poorly demarcated cytoplasm. Neuroendocrine tumors include carcinoids, small ("oat") cell carcinomas, medullary carcinoma of the thyroid, Merkel cell tumor, cutaneous neuroendocrine carcinoma, pancreatic islet cell tumors, and pheochromocytoma. Neurosecretory granules are found within the tumor cells. (Segen, Dictionary of Modern Medicine, 1992)Neoplasms, Cystic, Mucinous, and Serous: Neoplasms containing cyst-like formations or producing mucin or serum.Carcinoma, Intraductal, Noninfiltrating: A noninvasive (noninfiltrating) carcinoma of the breast characterized by a proliferation of malignant epithelial cells confined to the mammary ducts or lobules, without light-microscopy evidence of invasion through the basement membrane into the surrounding stroma.Neoplasm Proteins: Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of NEOPLASMS. Some neoplasm proteins are tumor antigens (ANTIGENS, NEOPLASM), i.e. they induce an immune reaction to their tumor. Many neoplasm proteins have been characterized and are used as tumor markers (BIOMARKERS, TUMOR) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm.Adenocarcinoma, Mucinous: An adenocarcinoma producing mucin in significant amounts. (From Dorland, 27th ed)Carcinoma, Medullary: A carcinoma composed mainly of epithelial elements with little or no stroma. Medullary carcinomas of the breast constitute 5%-7% of all mammary carcinomas; medullary carcinomas of the thyroid comprise 3%-10% of all thyroid malignancies. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1141; Segen, Dictionary of Modern Medicine, 1992)Tumor Cells, Cultured: Cells grown in vitro from neoplastic tissue. If they can be established as a TUMOR CELL LINE, they can be propagated in cell culture indefinitely.Nasopharyngeal Neoplasms: Tumors or cancer of the NASOPHARYNX.Colonic Neoplasms: Tumors or cancer of the COLON.Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.Mouth Neoplasms: Tumors or cancer of the MOUTH.Acute Lung Injury: A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological).Carcinoma, Lobular: A infiltrating (invasive) breast cancer, relatively uncommon, accounting for only 5%-10% of breast tumors in most series. It is often an area of ill-defined thickening in the breast, in contrast to the dominant lump characteristic of ductal carcinoma. It is typically composed of small cells in a linear arrangement with a tendency to grow around ducts and lobules. There is likelihood of axillary nodal involvement with metastasis to meningeal and serosal surfaces. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1205)Carcinoma, Mucoepidermoid: A tumor of both low- and high-grade malignancy. The low-grade grow slowly, appear in any age group, and are readily cured by excision. The high-grade behave aggressively, widely infiltrate the salivary gland and produce lymph node and distant metastases. Mucoepidermoid carcinomas account for about 21% of the malignant tumors of the parotid gland and 10% of the sublingual gland. They are the most common malignant tumor of the parotid. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p575; Holland et al., Cancer Medicine, 3d ed, p1240)Head and Neck Neoplasms: Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)Urinary Bladder Neoplasms: Tumors or cancer of the URINARY BLADDER.Antigens, Neoplasm: Proteins, glycoprotein, or lipoprotein moieties on surfaces of tumor cells that are usually identified by monoclonal antibodies. Many of these are of either embryonic or viral origin.Neoplasm Recurrence, Local: The local recurrence of a neoplasm following treatment. It arises from microscopic cells of the original neoplasm that have escaped therapeutic intervention and later become clinically visible at the original site.Stomach Neoplasms: Tumors or cancer of the STOMACH.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Carcinoma, Adenosquamous: A mixed adenocarcinoma and squamous cell or epidermoid carcinoma.Esophageal Neoplasms: Tumors or cancer of the ESOPHAGUS.Neoplasms, Second Primary: Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. The second neoplasm may have the same or different histological type and can occur in the same or different organs as the previous neoplasm but in all cases arises from an independent oncogenic event. The development of the second neoplasm may or may not be related to the treatment for the previous neoplasm since genetic risk or predisposing factors may actually be the cause.Neoplasm Transplantation: Experimental transplantation of neoplasms in laboratory animals for research purposes.Neoplasms, Experimental: Experimentally induced new abnormal growth of TISSUES in animals to provide models for studying human neoplasms.Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.Salivary Gland Neoplasms: Tumors or cancer of the SALIVARY GLANDS.RNA, Messenger: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.Lymphatic Metastasis: Transfer of a neoplasm from its primary site to lymph nodes or to distant parts of the body by way of the lymphatic system.Carcinoma, Endometrioid: An adenocarcinoma characterized by the presence of cells resembling the glandular cells of the ENDOMETRIUM. It is a common histological type of ovarian CARCINOMA and ENDOMETRIAL CARCINOMA. There is a high frequency of co-occurrence of this form of adenocarcinoma in both tissues.Carcinoma, Large Cell: A tumor of undifferentiated (anaplastic) cells of large size. It is usually bronchogenic. (From Dorland, 27th ed)Antineoplastic Agents: Substances that inhibit or prevent the proliferation of NEOPLASMS.Adenocarcinoma, Papillary: An adenocarcinoma containing finger-like processes of vascular connective tissue covered by neoplastic epithelium, projecting into cysts or the cavity of glands or follicles. It occurs most frequently in the ovary and thyroid gland. (Stedman, 25th ed)Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Adrenocortical Carcinoma: A malignant neoplasm of the ADRENAL CORTEX. Adrenocortical carcinomas are unencapsulated anaplastic (ANAPLASIA) masses sometimes exceeding 20 cm or 200 g. They are more likely to be functional than nonfunctional, and produce ADRENAL CORTEX HORMONES that may result in hypercortisolism (CUSHING SYNDROME); HYPERALDOSTERONISM; and/or VIRILISM.Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.Immunoenzyme Techniques: Immunologic techniques based on the use of: (1) enzyme-antibody conjugates; (2) enzyme-antigen conjugates; (3) antienzyme antibody followed by its homologous enzyme; or (4) enzyme-antienzyme complexes. These are used histologically for visualizing or labeling tissue specimens.Carcinoma, Merkel Cell: A carcinoma arising from MERKEL CELLS located in the basal layer of the epidermis and occurring most commonly as a primary neuroendocrine carcinoma of the skin. Merkel cells are tactile cells of neuroectodermal origin and histologically show neurosecretory granules. The skin of the head and neck are a common site of Merkel cell carcinoma, occurring generally in elderly patients. (Holland et al., Cancer Medicine, 3d ed, p1245)Mice, Nude: Mutant mice homozygous for the recessive gene "nude" which fail to develop a thymus. They are useful in tumor studies and studies on immune responses.Survival Rate: The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.Carcinoma, Embryonal: A highly malignant, primitive form of carcinoma, probably of germinal cell or teratomatous derivation, usually arising in a gonad and rarely in other sites. It is rare in the female ovary, but in the male it accounts for 20% of all testicular tumors. (From Dorland, 27th ed & Holland et al., Cancer Medicine, 3d ed, p1595)Carcinoma, Ductal: Malignant neoplasms involving the ductal systems of any of a number of organs, such as the MAMMARY GLANDS, the PANCREAS, the PROSTATE, or the LACRIMAL GLAND.Survival Analysis: A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.Laryngeal Neoplasms: Cancers or tumors of the LARYNX or any of its parts: the GLOTTIS; EPIGLOTTIS; LARYNGEAL CARTILAGES; LARYNGEAL MUSCLES; and VOCAL CORDS.Carcinoma, Pancreatic Ductal: Carcinoma that arises from the PANCREATIC DUCTS. It accounts for the majority of cancers derived from the PANCREAS.Parotid Neoplasms: Tumors or cancer of the PAROTID GLAND.Lung Volume Measurements: Measurement of the amount of air that the lungs may contain at various points in the respiratory cycle.Tongue Neoplasms: Tumors or cancer of the TONGUE.Carcinoma, Lewis Lung: A carcinoma discovered by Dr. Margaret R. Lewis of the Wistar Institute in 1951. This tumor originated spontaneously as a carcinoma of the lung of a C57BL mouse. The tumor does not appear to be grossly hemorrhagic and the majority of the tumor tissue is a semifirm homogeneous mass. (From Cancer Chemother Rep 2 1972 Nov;(3)1:325) It is also called 3LL and LLC and is used as a transplantable malignancy.Reverse Transcriptase Polymerase Chain Reaction: A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.Carcinoma, Signet Ring Cell: A poorly differentiated adenocarcinoma in which the nucleus is pressed to one side by a cytoplasmic droplet of mucus. It usually arises in the gastrointestinal system.Adenocarcinoma, Follicular: An adenocarcinoma of the thyroid gland, in which the cells are arranged in the form of follicles. (From Dorland, 27th ed)Uterine Cervical Neoplasms: Tumors or cancer of the UTERINE CERVIX.Carcinoma, Verrucous: A variant of well-differentiated epidermoid carcinoma that is most common in the oral cavity, but also occurs in the larynx, nasal cavity, esophagus, penis, anorectal region, vulva, vagina, uterine cervix, and skin, especially on the sole of the foot. Most intraoral cases occur in elderly male abusers of smokeless tobacco. The treatment is surgical resection. Radiotherapy is not indicated, as up to 30% treated with radiation become highly aggressive within six months. (Segen, Dictionary of Modern Medicine, 1992)Precancerous Conditions: Pathological processes that tend eventually to become malignant. (From Dorland, 27th ed)Kidney Neoplasms: Tumors or cancers of the KIDNEY.Gallbladder Neoplasms: Tumors or cancer of the gallbladder.Cell Proliferation: All of the processes involved in increasing CELL NUMBER including CELL DIVISION.Disease Progression: The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.Fatal Outcome: Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.Small Cell Lung Carcinoma: A form of highly malignant lung cancer that is composed of small ovoid cells (SMALL CELL CARCINOMA).Cystadenoma: A benign neoplasm derived from glandular epithelium, in which cystic accumulations of retained secretions are formed. In some instances, considerable portions of the neoplasm, or even the entire mass, may be cystic. (Stedman, 25th ed)Neoplasms, Radiation-Induced: Tumors, cancer or other neoplasms produced by exposure to ionizing or non-ionizing radiation.Gastrointestinal Neoplasms: Tumors or cancer of the GASTROINTESTINAL TRACT, from the MOUTH to the ANAL CANAL.Bronchial Neoplasms: Tumors or cancer of the BRONCHI.Lung Diseases, Interstitial: A diverse group of lung diseases that affect the lung parenchyma. They are characterized by an initial inflammation of PULMONARY ALVEOLI that extends to the interstitium and beyond leading to diffuse PULMONARY FIBROSIS. Interstitial lung diseases are classified by their etiology (known or unknown causes), and radiological-pathological features.Bile Duct Neoplasms: Tumors or cancer of the BILE DUCTS.Apoptosis: One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.Tumor Suppressor Protein p53: Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. A mutant or absent p53 protein has been found in LEUKEMIA; OSTEOSARCOMA; LUNG CANCER; and COLORECTAL CANCER.RNA, Neoplasm: RNA present in neoplastic tissue.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Uterine Neoplasms: Tumors or cancer of the UTERUS.Bone Neoplasms: Tumors or cancer located in bone tissue or specific BONES.Nose Neoplasms: Tumors or cancer of the NOSE.Neoplasms, Glandular and Epithelial: Neoplasms composed of glandular tissue, an aggregation of epithelial cells that elaborate secretions, and of any type of epithelium itself. The concept does not refer to neoplasms located in the various glands or in epithelial tissue.Endometrial Neoplasms: Tumors or cancer of ENDOMETRIUM, the mucous lining of the UTERUS. These neoplasms can be benign or malignant. Their classification and grading are based on the various cell types and the percent of undifferentiated cells.Adrenal Cortex Neoplasms: Tumors or cancers of the ADRENAL CORTEX.Keratins: A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.Liver Neoplasms, Experimental: Experimentally induced tumors of the LIVER.Cell Division: The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION.Myeloproliferative Disorders: Conditions which cause proliferation of hemopoietically active tissue or of tissue which has embryonic hemopoietic potential. They all involve dysregulation of multipotent MYELOID PROGENITOR CELLS, most often caused by a mutation in the JAK2 PROTEIN TYROSINE KINASE.Carcinoma, Papillary, Follicular: A thyroid neoplasm of mixed papillary and follicular arrangement. Its biological behavior and prognosis is the same as that of a papillary adenocarcinoma of the thyroid. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1271)Appendiceal Neoplasms: Tumors or cancer of the APPENDIX.Testicular Neoplasms: Tumors or cancer of the TESTIS. Germ cell tumors (GERMINOMA) of the testis constitute 95% of all testicular neoplasms.Neoplasms, Complex and Mixed: Neoplasms composed of more than one type of neoplastic tissue.Eye Neoplasms: Tumors or cancer of the EYE.Tissue Array Analysis: The simultaneous analysis of multiple samples of TISSUES or CELLS from BIOPSY or in vitro culture that have been arranged in an array format on slides or microchips.Endocrine Gland Neoplasms: Tumors or cancer of the ENDOCRINE GLANDS.Palatal Neoplasms: Tumors or cancer of the PALATE, including those of the hard palate, soft palate and UVULA.Antibodies, Monoclonal: Antibodies produced by a single clone of cells.Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)Intestinal Neoplasms: Tumors or cancer of the INTESTINES.Cisplatin: An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.Cystadenoma, Mucinous: A multilocular tumor with mucin secreting epithelium. They are most often found in the ovary, but are also found in the pancreas, appendix, and rarely, retroperitoneal and in the urinary bladder. They are considered to have low-grade malignant potential.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Adenocarcinoma, Clear Cell: An adenocarcinoma characterized by the presence of varying combinations of clear and hobnail-shaped tumor cells. There are three predominant patterns described as tubulocystic, solid, and papillary. These tumors, usually located in the female reproductive organs, have been seen more frequently in young women since 1970 as a result of the association with intrauterine exposure to diethylstilbestrol. (From Holland et al., Cancer Medicine, 3d ed)Adenoma, Oxyphilic: A usually benign glandular tumor composed of oxyphil cells, large cells with small irregular nuclei and dense acidophilic granules due to the presence of abundant MITOCHONDRIA. Oxyphil cells, also known as oncocytes, are found in oncocytomas of the kidney, salivary glands, and endocrine glands. In the thyroid gland, oxyphil cells are known as Hurthle cells and Askanazy cells.Biopsy: Removal and pathologic examination of specimens in the form of small pieces of tissue from the living body.Blotting, Western: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.Carcinogens: Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.Sweat Gland NeoplasmsThymus Neoplasms: Tumors or cancer of the THYMUS GLAND.Vulvar Neoplasms: Tumors or cancer of the VULVA.Combined Modality Therapy: The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Disease-Free Survival: Period after successful treatment in which there is no appearance of the symptoms or effects of the disease.Cystadenocarcinoma, Mucinous: A malignant cystic or semisolid tumor most often occurring in the ovary. Rarely, one is solid. This tumor may develop from a mucinous cystadenoma, or it may be malignant at the onset. The cysts are lined with tall columnar epithelial cells; in others, the epithelium consists of many layers of cells that have lost normal structure entirely. In the more undifferentiated tumors, one may see sheets and nests of tumor cells that have very little resemblance to the parent structure. (Hughes, Obstetric-Gynecologic Terminology, 1972, p184)Cystadenocarcinoma, Serous: A malignant cystic or semicystic neoplasm. It often occurs in the ovary and usually bilaterally. The external surface is usually covered with papillary excrescences. Microscopically, the papillary patterns are predominantly epithelial overgrowths with differentiated and undifferentiated papillary serous cystadenocarcinoma cells. Psammoma bodies may be present. The tumor generally adheres to surrounding structures and produces ascites. (From Hughes, Obstetric-Gynecologic Terminology, 1972, p185)Ki-67 Antigen: A CELL CYCLE and tumor growth marker which can be readily detected using IMMUNOCYTOCHEMISTRY methods. Ki-67 is a nuclear antigen present only in the nuclei of cycling cells.Loss of Heterozygosity: The loss of one allele at a specific locus, caused by a deletion mutation; or loss of a chromosome from a chromosome pair, resulting in abnormal HEMIZYGOSITY. It is detected when heterozygous markers for a locus appear monomorphic because one of the ALLELES was deleted.Mice, Inbred BALB CNeoplasms, Connective and Soft Tissue: Neoplasms developing from some structure of the connective and subcutaneous tissue. The concept does not refer to neoplasms located in connective or soft tissue.Pulmonary Alveoli: Small polyhedral outpouchings along the walls of the alveolar sacs, alveolar ducts and terminal bronchioles through the walls of which gas exchange between alveolar air and pulmonary capillary blood takes place.Case-Control Studies: Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.Cystadenocarcinoma: A malignant neoplasm derived from glandular epithelium, in which cystic accumulations of retained secretions are formed. The neoplastic cells manifest varying degrees of anaplasia and invasiveness, and local extension and metastases occur. Cystadenocarcinomas develop frequently in the ovaries, where pseudomucinous and serous types are recognized. (Stedman, 25th ed)Genes, p53: Tumor suppressor genes located on the short arm of human chromosome 17 and coding for the phosphoprotein p53.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Neoplasms, Plasma Cell: Neoplasms associated with a proliferation of a single clone of PLASMA CELLS and characterized by the secretion of PARAPROTEINS.Signal Transduction: The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.Antineoplastic Combined Chemotherapy Protocols: The use of two or more chemicals simultaneously or sequentially in the drug therapy of neoplasms. The drugs need not be in the same dosage form.Gene Expression Profiling: The determination of the pattern of genes expressed at the level of GENETIC TRANSCRIPTION, under specific circumstances or in a specific cell.Mammary Neoplasms, Experimental: Experimentally induced mammary neoplasms in animals to provide a model for studying human BREAST NEOPLASMS.Embryonal Carcinoma Stem Cells: The malignant stem cells of TERATOCARCINOMAS, which resemble pluripotent stem cells of the BLASTOCYST INNER CELL MASS. The EC cells can be grown in vitro, and experimentally induced to differentiate. They are used as a model system for studying early embryonic cell differentiation.Transplantation, Heterologous: Transplantation between animals of different species.Dog Diseases: Diseases of the domestic dog (Canis familiaris). This term does not include diseases of wild dogs, WOLVES; FOXES; and other Canidae for which the heading CARNIVORA is used.Total Lung Capacity: The volume of air contained in the lungs at the end of a maximal inspiration. It is the equivalent to each of the following sums: VITAL CAPACITY plus RESIDUAL VOLUME; INSPIRATORY CAPACITY plus FUNCTIONAL RESIDUAL CAPACITY; TIDAL VOLUME plus INSPIRATORY RESERVE VOLUME plus functional residual capacity; or tidal volume plus inspiratory reserve volume plus EXPIRATORY RESERVE VOLUME plus residual volume.Neoplasm Grading: Methods which attempt to express in replicable terms the level of CELL DIFFERENTIATION in neoplasms as increasing ANAPLASIA correlates with the aggressiveness of the neoplasm.Common Bile Duct Neoplasms: Tumor or cancer of the COMMON BILE DUCT including the AMPULLA OF VATER and the SPHINCTER OF ODDI.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Mandibular Neoplasms: Tumors or cancer of the MANDIBLE.alpha-Fetoproteins: The first alpha-globulins to appear in mammalian sera during FETAL DEVELOPMENT and the dominant serum proteins in early embryonic life.Extravascular Lung Water: Water content outside of the lung vasculature. About 80% of a normal lung is made up of water, including intracellular, interstitial, and blood water. Failure to maintain the normal homeostatic fluid exchange between the vascular space and the interstitium of the lungs can result in PULMONARY EDEMA and flooding of the alveolar space.Neoplasms, Vascular Tissue: Neoplasms composed of vascular tissue. This concept does not refer to neoplasms located in blood vessels.Rectal Neoplasms: Tumors or cancer of the RECTUM.Gene Expression: The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.Lymphoma: A general term for various neoplastic diseases of the lymphoid tissue.Kaplan-Meier Estimate: A nonparametric method of compiling LIFE TABLES or survival tables. It combines calculated probabilities of survival and estimates to allow for observations occurring beyond a measurement threshold, which are assumed to occur randomly. Time intervals are defined as ending each time an event occurs and are therefore unequal. (From Last, A Dictionary of Epidemiology, 1995)Maxillary Neoplasms: Cancer or tumors of the MAXILLA or upper jaw.Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.Carcinosarcoma: A malignant neoplasm that contains elements of carcinoma and sarcoma so extensively intermixed as to indicate neoplasia of epithelial and mesenchymal tissue. (Stedman, 25th ed)Bronchoalveolar Lavage Fluid: Washing liquid obtained from irrigation of the lung, including the BRONCHI and the PULMONARY ALVEOLI. It is generally used to assess biochemical, inflammatory, or infection status of the lung.Genes, Tumor Suppressor: Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and unregulated growth is possible.Neoplasms, Adnexal and Skin Appendage: Neoplasms composed of sebaceous or sweat gland tissue or tissue of other skin appendages. The concept does not refer to neoplasms located in the sebaceous or sweat glands or in the other skin appendages.Soft Tissue Neoplasms: Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc.Cystadenoma, Serous: A cystic tumor of the ovary, containing thin, clear, yellow serous fluid and varying amounts of solid tissue, with a malignant potential several times greater than that of mucinous cystadenoma (CYSTADENOMA, MUCINOUS). It can be unilocular, parvilocular, or multilocular. It is often bilateral and papillary. The cysts may vary greatly in size. (Dorland, 27th ed; from Hughes, Obstetric-Gynecologic Terminology, 1972)Duodenal Neoplasms: Tumors or cancer of the DUODENUM.Keratin-7: A type II keratin found associated with KERATIN-19 in ductal epithelia and gastrointestinal epithelia.Mice, Inbred C57BLNeovascularization, Pathologic: A pathologic process consisting of the proliferation of blood vessels in abnormal tissues or in abnormal positions.Vascular Neoplasms: Neoplasms located in the vasculature system, such as ARTERIES and VEINS. They are differentiated from neoplasms of vascular tissue (NEOPLASMS, VASCULAR TISSUE), such as ANGIOFIBROMA or HEMANGIOMA.Pneumonectomy: The excision of lung tissue including partial or total lung lobectomy.Receptor, Epidermal Growth Factor: A cell surface receptor involved in regulation of cell growth and differentiation. It is specific for EPIDERMAL GROWTH FACTOR and EGF-related peptides including TRANSFORMING GROWTH FACTOR ALPHA; AMPHIREGULIN; and HEPARIN-BINDING EGF-LIKE GROWTH FACTOR. The binding of ligand to the receptor causes activation of its intrinsic tyrosine kinase activity and rapid internalization of the receptor-ligand complex into the cell.Peritoneal Neoplasms: Tumors or cancer of the PERITONEUM.Carcinoembryonic Antigen: A glycoprotein that is secreted into the luminal surface of the epithelia in the gastrointestinal tract. It is found in the feces and pancreaticobiliary secretions and is used to monitor the response to colon cancer treatment.Adenoma: A benign epithelial tumor with a glandular organization.Cell Line: Established cell cultures that have the potential to propagate indefinitely.Papilloma: A circumscribed benign epithelial tumor projecting from the surrounding surface; more precisely, a benign epithelial neoplasm consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic cells. (Stedman, 25th ed)
Polychlorinated dibenzodioxins
Risk factors for tuberculosis
Category:Cancer - Simple English Wikipedia, the free encyclopedia
ಮೆದುಳಿನ ಕ್ಯಾನ್ಸರ್ ಗೆಡ್ದೆ(ಊತ) - ವಿಕಿಪೀಡಿಯ
위키백과:미번역 문서/의학 - 위키백과, 우리 모두의 백과사전
Category:Infobox medical condition (new)
Histopathologic, immunophenotypic and cytogenetic features of pulmonary mucoepidermoid carcinoma<...
NCT00094094 | Lung Neoplasms, Non-small Cell Lung Carcinoma Clinical Trial | Pfizer
Observing Patients With Palliative Asymptomatic Centrally Located Advanced Non-small Cell Lung Carcinoma (NSCLC) - Full Text...
Erlotinib and Standard Platinum-Based Chemotherapy for Newly Diagnosed, Advanced Non-Small Cell Carcinoma of the Lung - Full...
SC-002 in Small Cell Lung Cancer and Large Cell Neuroendocrine Carcinoma - Full Text View - ClinicalTrials.gov
Metastatic properties of murine sarcomas and carcinomas. I. Positive correlation with lung colonization and lack of correlation...
Increased expression of connexin 26 in the invasive component of lung squamous cell carcinoma: significant correlation with...
NIOSHTIC-2 Publications Search - 20034766 - Culmination of MG132-induced apoptosis in human lung cancer NCI-H1703 cells...
CD44v6 expression in primary bronchioloalveolar carcinoma and conventional pulmonary adenocarcinoma.
BAY43-9006 - Phase II Study in Non-Small Cell Lung Carcinoma (NSCLC)
Study of AXL1717 Compared to Docetaxel to Treat Squamous Cell Carcinoma or Adenocarcinoma of the Lung
Genomic Profiling of Large-Cell Neuroendocrine Carcinoma of the Lung | Clinical Cancer Research
Salivary gland-type lung carcinomas are uncommon neoplasms from the lung both - Abl Family Kinases Regulate Endothelial Barrier...
LUX-Lung 7: A Phase IIb Trial of Afatinib(BIBW2992) Versus Gefitinib for the Treatment of 1st Line EGFR Mutation Positive...
Cytosolic levels of neuron-specific enolase in squamous cell carcinomas of the lung. | CureHunter
Gene Ontology Classifications
Pathology Overview, Pathology Basis of Occupational Lung Disease, References | NIOSH | CDC
Soblidotin in Treating Patients With Progressive Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Oltipraz in the Prevention of Lung Cancer in People Who Smoke
Giant cell carcinoma | Article about giant cell carcinoma by The Free Dictionary
Adenosquamous carcinoma of the lung | Directory of Open Access Journals
MetastaticBronchogenicPatientsSituHistologicAbstractPulmonary neoplasmCancerRenal cell carcMerkel Cell CarcEpithelial cellsMalignant neoplasm of lungPleuraLarge cell carcinomaPulmonaryCarcinoid TumorSarcomatoid carcinomaDiseaseChronicTumourClinicalAdenocarcinomasTissueLCNECPapillaryBronchioloalveolarDiseasesBronchialBronchoalveolarEGFRCell carcinomasTumor cellsPoorly differentiated squamousPrimary and metastaticBreast CarcinomasMyeloproliferative neoplasmsProstate carcinoma
Metastatic1
- one developed metastatic pulmonary mucoepidermoid carcinoma. (elsevier.com)
Bronchogenic1
- Nonmucinous bronchioloalveolar carcinoma tends to be more localized and has a lower frequency of bronchogenic spread than mucinous bronchioloalveolar carcinoma. (elsevier.com)
Patients1
- More than half of all patients with bronchioloalveolar carcinoma are asymptomatic. (elsevier.com)
Situ1
- Thirty nine pulmonary mucoepidermoid carcinoma (4 low, 30 intermediate, 5 high grade) contained mucous, epidermoid and intermediate cells and lacked keratinization and in situ carcinoma of the overlying epithelium. (elsevier.com)
Histologic1
- Few studies have characterized the histologic and immunophenotypic features of pulmonary mucoepidermoid carcinoma. (elsevier.com)
Abstract1
- abstract = "Pulmonary mucoepidermoid carcinoma is an uncommon but distinctive manifestation of mucoepidermoid carcinoma. (elsevier.com)
Pulmonary neoplasm1
- Bronchioloalveolar carcinoma is characterized pathologically by a pulmonary neoplasm showing lepidic growth. (elsevier.com)
Cancer120
- The aim of the study is to assess current practice within PROP & lung teams, for treating asymptomatic patients with centrally located non-small cell lung cancer (NSCLC), and to observe outcomes for those patients receiving immediate or deferred RT. (clinicaltrials.gov)
- This is a Phase 1a/1b study of SC-002 in patients with relapsed small cell lung cancer (SCLC) or large cell neuroendocrine carcinoma (LCNEC). (clinicaltrials.gov)
- Part 1A is a dose escalation study in patients with small cell lung cancer or large cell neuroendocrine carcinoma with cytologically confirmed, limited or extensive SCLC or LCNEC that have relapsed or refractory limited or extensive disease following no more than 2 prior chemotherapy regimens. (clinicaltrials.gov)
- Culmination of MG132-induced apoptosis in human lung cancer NCI-H1703 cells depends on a positive feedback of caspase activation and Mcl-1 cleavage. (cdc.gov)
- Non-small cell lung carcinoma (NSCLC) is the leading cause of cancer death in both men and women in the United States. (cdc.gov)
- Giant-cell carcinoma of the lung (GCCL) is a rare histological form of large-cell lung carcinoma, a subtype of undifferentiated lung cancer, traditionally classified within the non-small-cell lung carcinomas (NSCLC). (wikipedia.org)
- However, in a more recent series of 4,212 consecutive lung cancer cases, only one (0.024%) lesion was determined to be a "pure" giant-cell carcinoma after complete sectioning of all available tumor tissue. (wikipedia.org)
- Non-Small-Cell lung Cancer (NSCLC) is the most common form of lung cancer, and treatment with cytotoxic chemotherapy only provides a 10% reduction in the risk of death in patients with advanced NSCLC. (knowcancer.com)
- Although large-cell neuroendocrine carcinoma (LCNEC) of the lung shares many clinical characteristics with small-cell lung cancer (SCLC), little is known about its molecular features. (aacrjournals.org)
- We performed targeted capture sequencing of all the coding exons of 244 cancer-related genes on 78 LCNEC samples [65 surgically resected cases, including 10 LCNECs combined with non-small cell lung cancer (NSCLC) types analyzed separately, and biopsies of 13 advanced cases]. (aacrjournals.org)
- Large-cell neuroendocrine carcinoma (LCNEC) of the lung, which has been histologically categorized as high-grade neuroendocrine carcinoma with small-cell lung cancer (SCLC), is a highly malignant tumor with a poor prognosis. (aacrjournals.org)
- The American Cancer Society (ACS) estimated that in 1998, at least 172,000 new cases of lung cancer were diagnosed, and that lung cancer accounted for 28% of all cancer deaths, or approximately 160,000 people. (encyclopedia.com)
- Only 15 percent of people with lung cancer will live five years. (encyclopedia.com)
- Primary lung cancer (also called adenocarcinoma) starts in the lung itself. (encyclopedia.com)
- Primary lung cancer is divided into small cell lung cancer and non-small cell lung cancer, depending on how the cells look under the microscope. (encyclopedia.com)
- Secondary lung cancer is cancer that starts somewhere else in the body (for example, the breast or colon) and spreads to the lungs. (encyclopedia.com)
- Lung cancer is rare among young adults. (encyclopedia.com)
- In 1987, lung cancer replaced breast cancer as the number one cancer killer among women. (encyclopedia.com)
- Tobacco smoking is the leading cause of lung cancer. (encyclopedia.com)
- Smoking marijuana cigarettes is considered yet another risk factor for cancer of the lung. (encyclopedia.com)
- Repeated exposure to asbestos fibers, either at home or in the workplace, also is considered a risk factor for lung cancer. (encyclopedia.com)
- Studies show that compared to the general population, asbestos workers are seven times more likely to die from lung cancer. (encyclopedia.com)
- Asbestos workers who smoke increase their risk of developing lung cancer by 50-100 times. (encyclopedia.com)
- Besides asbestos, mining industry workers who are exposed to coal products or radioactive substances, such as uranium, and workers exposed to chemicals, such as arsenic, vinyl chloride, mustard gas , and other carcinogens, also have a higher than average risk of contracting lung cancer. (encyclopedia.com)
- High levels of a radioactive gas (radon) that cannot be seen or smelled pose a risk for lung cancer. (encyclopedia.com)
- Other forms of environmental pollution (e.g., auto exhaust fumes) also may slightly increase the risk of lung cancer. (encyclopedia.com)
- In 2002, a study in the Journal of the American Medical Association (JAMA) linked for the first time long-term exposure to fine-particle air pollution to lung cancer deaths. (encyclopedia.com)
- The risk of death from lung cancer increased substantially for people living in the most heavily polluted metropolitan areas. (encyclopedia.com)
- This scarring may increase the risk of developing lung cancer. (encyclopedia.com)
- Although the exact cause of lung cancer is not known, people with a family history of lung cancer appear to have a slightly higher risk of contracting the disease. (encyclopedia.com)
- In 2003, researchers were continuing work aimed at learning why some smokers were more susceptible to lung cancer than others. (encyclopedia.com)
- They discovered a type of DNA repair characteristic apparent in smokers who were less likely to get lung cancer. (encyclopedia.com)
- Lung cancer is a disease in which certain cells in the lungs become abnormal and multiply uncontrollably to form a tumor . (medlineplus.gov)
- Lung cancer may not cause signs or symptoms in its early stages. (medlineplus.gov)
- Some people with lung cancer have chest pain, frequent coughing, blood in the mucus, breathing problems, trouble swallowing or speaking, loss of appetite and weight loss, fatigue, or swelling in the face or neck. (medlineplus.gov)
- Lung cancer occurs most often in adults in their sixties or seventies. (medlineplus.gov)
- Lung cancer is generally divided into two types, small cell lung cancer and non-small cell lung cancer, based on the size of the affected cells when viewed under a microscope. (medlineplus.gov)
- Non-small cell lung cancer accounts for 85 percent of lung cancer, while small cell lung cancer accounts for the remaining 15 percent. (medlineplus.gov)
- Non-small cell lung cancer is divided into three main subtypes: adenocarcinoma, squamous cell carcinoma, and large cell lung carcinoma. (medlineplus.gov)
- In the United States, lung cancer is the second most commonly diagnosed cancer, after breast cancer , accounting for about one-quarter of all cancer diagnoses. (medlineplus.gov)
- It is estimated that more than 222,500 people develop lung cancer each year. (medlineplus.gov)
- Approximately 6.6 percent of individuals will develop lung cancer during their lifetime. (medlineplus.gov)
- An estimated 72 to 80 percent of lung cancer cases occur in tobacco smokers. (medlineplus.gov)
- Lung cancer is the leading cause of cancer deaths, accounting for an estimated 27 percent of all cancer deaths in the United States. (medlineplus.gov)
- In nearly all cases of lung cancer, these genetic changes are acquired during a person's lifetime and are present only in certain cells in the lung. (medlineplus.gov)
- Somatic mutations in many different genes have been found in lung cancer cells. (medlineplus.gov)
- A variant of peripheral lung cancer. (cdc.gov)
- Non-small-cell lung carcinoma ( NSCLC ) is any type of epithelial lung cancer other than small cell lung carcinoma (SCLC). (wikipedia.org)
- Lung cancer in people who have never smoked is almost universally NSCLC, with a sizeable majority being adenocarcinoma. (wikipedia.org)
- Adenocarcinoma of the lung is currently the most common type of lung cancer in "never smokers" (lifelong non-smokers). (wikipedia.org)
- Historically, adenocarcinoma was more often seen peripherally in the lungs than small cell lung cancer and squamous cell lung cancer, both of which tended to be more often centrally located. (wikipedia.org)
- It is closely correlated with a history of tobacco smoking , more so than most other types of lung cancer . (wikipedia.org)
- LCLC is, in effect, a "diagnosis of exclusion", in that the tumor cells lack light microscopic characteristics that would classify the neoplasm as a small-cell carcinoma, squamous-cell carcinoma, adenocarcinoma, or other more specific histologic type of lung cancer. (wikipedia.org)
- 3Zhejiang Key Laboratory of Diagnosis & Treatment Technology on Thoracic Oncology (Lung and Esophagus), Zhejiang Cancer Hospital, Hangzhou, People's Republic of China Abstract: Adenosquamous carcinoma of the lung (ASC), a relatively rare subtype of non-small-cell lung cancer, is defined as a malignancy containing components of lung adenocarcinoma (ADC) and lung squamous cell carcinoma (SCC). (doaj.org)
- Combined small cell lung carcinoma (or c-SCLC, and rarely rendered as "small-cell lung carcinoma") is a form of multiphasic lung cancer that is diagnosed by a pathologist when a malignant tumor arising from transformed cells originating in lung tissue contains a component of small cell lung carcinoma (SCLC) admixed with one (or more) components of non-small cell lung carcinoma (NSCLC). (wikipedia.org)
- Lung cancer is a large and exceptionally heterogeneous family of malignancies. (wikipedia.org)
- Over 50 different histological variants are explicitly recognized within the 2004 revision of the World Health Organization (WHO) typing system ("WHO-2004"), currently the most widely used lung cancer classification scheme. (wikipedia.org)
- Under WHO-2004, lung carcinomas are divided into 8 major taxa: Squamous cell carcinoma Small cell carcinoma Adenocarcinoma Large cell carcinoma Adenosquamous carcinoma Sarcomatoid carcinoma Carcinoid tumor Salivary gland-like carcinoma SCLC is generally considered to be the most aggressive of these major forms of lung cancer, with the worst long term prognosis and survival rates. (wikipedia.org)
- With 220,000 cases of newly diagnosed lung cancer in the U.S. each year, it can be estimated that between 8,800 and 13,200 of these are c-SCLC. (wikipedia.org)
- Porcel JM, Gasol A, Bielsa S, Civit C, Light RW, Salud A. Clinical features and survival of lung cancer patients with pleural effusions. (springer.com)
- The IASLC lung cancer staging project: proposals for the revisions of the M descriptors in the forthcoming eighth edition of the TNM classification of lung cancer. (springer.com)
- Yoneda KY, Mathur PN, Gasparini S. The evolving role of interventional pulmonary in the interdisciplinary approach to the staging and management of lung cancer: Part III: diagnosis and management of malignant pleural effusions. (springer.com)
- Kimura M, Tojo T, Naito H, Nagata Y, Kawai N, Taniguchi S. Effects of a simple intraoperative intrathoracic hyperthermotherapy for lung cancer with malignant pleural effusion or dissemination. (springer.com)
- Determine the objective tumor response rate and duration of response in patients with progressive locally advanced or metastatic non-small cell lung cancer treated with soblidotin as second-line therapy after receiving prior platinum-based chemotherapy. (bioportfolio.com)
- Lung cancer is the number one cancer killer in the USA. (bioportfolio.com)
- Early stage lung cancer is asymptomatic. (bioportfolio.com)
- Most patients with lung cancer are usually symptomatic at diagnosis and already have advanc. (bioportfolio.com)
- RATIONALE: Doctors can diagnose lung cancer by collecting mucus coughed up from the lungs and examining it under a microscope to look for cancer cells. (bioportfolio.com)
- The study goal is to collect blood samples from individuals at risk for lung cancer in order to identify protein markers for diagnosis of lung cancer in the Chinese population. (bioportfolio.com)
- Cost-utility analysis of a potential lung cancer screening program for a high-risk population in Germany: A modelling approach. (bioportfolio.com)
- Lung cancer is the leading cause of cancer death in Germany. (bioportfolio.com)
- Although several randomized trials in Europe have evaluated the effectiveness of lung cancer screening programs, evidence on the cost-effec. (bioportfolio.com)
- Lung Cancer Among Women in the United States. (bioportfolio.com)
- November marks Lung Cancer Awareness Month, and reminds us that lung cancer is the leading cause of cancer death among women in the United States. (bioportfolio.com)
- Lung Cancer: One Disease or Many. (bioportfolio.com)
- Lung cancer is classified as a single entity comprised of multiple histological subtypes. (bioportfolio.com)
- An Update on the European Lung Cancer Screening Trials and Comparison of Lung Cancer Screening Recommendations in Europe. (bioportfolio.com)
- While lung cancer screening has been implemented in the United States, it is still under consideration in Europe. (bioportfolio.com)
- Lifetime Smoking History and Risk of Lung Cancer: Results From the Framingham Heart Study. (bioportfolio.com)
- The relative risk of lung cancer decreases with years since quitting (YSQ) smoking, but risk beyond 25 YSQ remains unclear. (bioportfolio.com)
- Current lung cancer screening guidelines, which exclude smokers with more th. (bioportfolio.com)
- lung cancer in people who smoke. (bioportfolio.com)
- Lung cancer is one of the deadliest malignancies. (bioportfolio.com)
- The immune checkpoint-blockade (ICB) tumor therapy has led to striking improvement of long-term survival for some lung cancer patients. (bioportfolio.com)
- MicroRNA-1246 inhibits cell invasion and epithelial mesenchymal transition process by targeting CXCR4 in lung cancer cells. (bioportfolio.com)
- Recent studies have indicated that microRNAs (miRNAs) are closely related to lung cancer. (bioportfolio.com)
- Asbestos is a known risk factor for several malignant diseases, including lung cancer and mesothelioma, and has more recently been implicated in pharyngeal and laryngeal cancer. (cdc.gov)
- Hao Y, Yasmin-Karim S, Moreau M, Sinha N, Sajo E, Ngwa W. Enhancing radiotherapy for lung cancer using immunoadjuvants delivered in situ from new design radiotherapy biomaterials: a preclinical study. (harvard.edu)
- Takahashi Y, Izumi Y, Matsutani N, Dejima H, Nakayama T, Okamura R, Uehara H, Kawamura M. Optimized magnitude of cryosurgery facilitating anti-tumor immunoreaction in a mouse model of Lewis lung cancer. (harvard.edu)
- The purpose of this randomized, open-label, 2-arm, Phase 3 study is to assess the assess the efficacy, safety and tolerability of rovalpituzumab tesirine versus topotecan in participants with advanced or metastatic Small Cell Lung Cancer (SCLC) with high levels of delta-like protein 3 (DLL3) and who have first disease progression during or following front-line platinum-based chemotherapy. (fredhutch.org)
- In fact, cancer in the lungs is more often metastatic disease rather than a primary neoplasm. (microscopyu.com)
- His area of clinical expertise includes pulmonary disease, pediatric neoplasia, pediatric lung disease, pathology and lung cancer. (hopkinsmedicine.org)
- We propose that TFP might be capable of inhibiting one or more elements of the DNA DSB repair machinery, thereby increasing the cytotoxicity of bleomycin in lung cancer cells. (diva-portal.org)
- Survival Benefit of Palliative Local Treatments and Efficacy of Different Pharmacotherapies in Colorectal Cancer With Lung Metastasis: Results From. (nih.gov)
- For most colorectal cancer patients with initial lung metastasis (LM), the only suitable treatments are palliative, including palliative local therapy and pharmacotherapy. (nih.gov)
- Prestwich, from Salt Lake City, has flown 20 missions in the past year, which have included flying a little girl from Saratoga Springs to Los Angeles for retinal blastoma treatment, transporting a healthcare professional going to Native American tribes to perform cancer screenings and promote education, and flying a Wendover, UT man to receive treatment for Lung Cancer. (thefreedictionary.com)
- It is more commonly associated with non-small-cell lung cancer, but the temporal association with Bowen's disease in the absence of other chemical or occupational exposure strongly points to a causal role for arsenic in this case of small-cell lung cancer. (thefreelibrary.com)
- A diagnosis of extensive stage small-cell lung cancer was made. (thefreelibrary.com)
- Clinicopathological analysis of loss of fragile histidine triad expression in lung cancer]. (curehunter.com)
- Metastatic neoplasms to the breast generally occur in the setting of disseminated metastatic disease, however patients may present with a breast mass as the first manifestation of metastatic cancer[ 4 ]. (pubmedcentralcanada.ca)
- Non-small Cell Lung Carcinoma is also known as non-small cell lung carcinoma, nonsmall cell lung cancer, nsclc, non-small cell lung cancer (disorder), carcinoma, non-small-cell lung, carcinoma non-small cell lung, carcinoma of lung. (novusbio.com)
- To assess the effectiveness and safety of intensified chemotherapy with haematopoietic progenitors (ICHP) in patients with small-cell lung cancer. (york.ac.uk)
- Randomised phase II and III clinical trials that compared ICHP to control chemotherapy without haematopoietic progenitors in patients with small-cell lung cancer were eligible for inclusion. (york.ac.uk)
- This is a case of metastatic lung cancer of the lymphoepithelial-like carcinoma (LELC) variant who first presented with symptomatic brain metastasis. (springermedizin.de)
- Analysis of pleural plaque found at lung cancer screening examination. (nii.ac.jp)
- To determine the demographic and clinical characteristics of patients with non-small cell lung cancer (NSCLC), as well as their disease course, by age group and gender. (scielo.br)
- Background Lung cancer survival is socioeconomically patterned, and socioeconomic inequalities in receipt of treatment have been demonstrated. (bmj.com)
- Cancer registry, Hospital Episode Statistics and lung cancer audit data were linked in order to investigate the contribution of these inequalities to socioeconomic inequalities in lung cancer survival. (bmj.com)
- Methods Logistic regression was used to examine the likelihood of being alive 2 years after diagnosis, by socioeconomic position, for 22 967 lung cancer patients diagnosed in 2006-2009, and in a subset with stage recorded (n=5233). (bmj.com)
- Conclusions Socioeconomic inequalities in survival from lung cancer were statistically explained by socioeconomic inequalities in receipt of treatment, but not by timeliness of referral and treatment. (bmj.com)
- What role does receipt of, and time to, treatment play in socioeconomic inequalities in lung cancer survival? (bmj.com)
- Although current clinical guidelines focus on target times for referral and treatment, our results suggest that a clinical focus on ensuring equity of treatment for lung cancer is likely to reduce socioeconomic inequalities in survival, and improve overall survival. (bmj.com)
- As inflammatory myositis can be a paraneoplastic feature of neoplasms such as lung cancer, colon cancer and non-Hodgkin lymphoma, it was suggested that the patient might have an occult neoplasm. (pubmedcentralcanada.ca)
- This analysis from two large retrospective lung cancer cohorts found that 9 of 13 patients (69.2%) with sarcomatoid carcinomas were positive for PD-L1. (oncologynurseadvisor.com)
- The shortest survival time is observed in malignant effusions secondary to lung cancer and the longest in ovarian cancer, while malignant effusions due to an unknown primary have an intermediate survival time [ 1 ]. (ispub.com)
- Currently, lung cancer is the most common metastatic tumor to the pleura in men and breast cancer in women. (ispub.com)
- Treatment-related death in patients with small-cell lung cancer in phase III trials over the last two decades. (nih.gov)
- Treatment-related death (TRD) remains a serious problem in small-cell lung cancer (SCLC), despite recent improvements in supportive care. (nih.gov)
- The most common neoplasms that metastasize to the heart are lung, stomach, breast and esophageal cancer, as well as those of malignant melanoma and lymphoma. (scmr.org)
- Choroid plexus carcinomas occasionally arise in association with hereditary cancer predisposition syndromes, including the Li-Fraumeni and rhabdoid predisposition syndromes, with germline mutations of TP53 and hSNF5/INI1/SMARCB1, respectively. (medscape.com)
Renal cell carc2
- Number 15-04: Metastatic renal cell carcinoma presenting as ST-segment elevation myocardial. (scmr.org)
- 49-year-old gentleman diagnosed with T3aN0M1 metastatic renal cell carcinoma in September 2010, underwent a right-sided nephrectomy the same month. (scmr.org)
Merkel Cell Carc9
- Also searched for Merkel cell carcinoma . (clinicaltrials.gov)
- Merkel cell carcinoma (MCC) is a rare, aggressive neuroendocrine tumor of the skin with a mortality rate of approximately 25% (Peloschek et al. (hindawi.com)
- Merkel cell carcinoma is a rare and highly aggressive neuroendocrine tumor of the skin. (hindawi.com)
- Unfortunately, in clinical practice, lesions highly suspicious for Merkel cell carcinoma are often biopsied or nonaccurately resected with close margins [ 2 ]. (hindawi.com)
- In fact, patients presenting with unclear new skin lesions should undergo clinical examination, and lesion still highly suspicious for Merkel cell carcinoma should be excised with clear and wide margins. (hindawi.com)
- This growing incidence rate has given a significant input for a growing interest in disease management of patients with Merkel cell carcinoma [ 15 , 16 ]. (hindawi.com)
- Unfortunately, there is sparse literature on imaging algorithms in patients with Merkel cell carcinoma and no widely accepted guidelines for imaging of Merkel cell carcinoma are available [ 5 , 8 ]. (hindawi.com)
- This paper reviews the literature on imaging of Merkel cell carcinoma discussing the role of the most recent imaging and diagnostic tools. (hindawi.com)
- In regard to Merkel cell carcinoma, work up and staging of the neck should be started with an ultrasonographic examination [ 2 ]. (hindawi.com)
Epithelial cells4
- Large cell carcinoma arises from epithelial cells that line the lungs. (medlineplus.gov)
- Large cell lung carcinoma (LCLC) is a heterogeneous group of undifferentiated malignant neoplasms originating from transformed epithelial cells in the lung. (wikipedia.org)
- Approximately 99% of lung cancers are carcinoma, a term that indicates that the malignant neoplasm is composed of, or descended from, cells of epithelial lineage (i.e. derived from embryonic endoderm, as is the case in lung carcinomas, or from ectoderm), and/or that the malignant cells exhibit tissue architectural, cytological, or molecular features characteristically found in epithelial cells. (wikipedia.org)
- Determine the effect of oltipraz on the level of BP-7,8-diol-9,10-epoxide (BPDE) DNA adducts in the lung lining cells (macrophages and bronchial epithelial cells) of smokers. (bioportfolio.com)
Malignant neoplasm of lung1
- Research of Non-small Cell Lung Carcinoma has been linked to Malignant Neoplasm Of Lung, Malignant Neoplasms, Lung Neoplasms, Neoplasms, Carcinoma. (novusbio.com)
Pleura3
- Neoplasms of the pleura. (cdc.gov)
- WHO classification of tumours of the lung, pleura, thymus and heart. (springer.com)
- Protecting each lung is the pleura, a two-layered membrane that envelops the lung and contains lubricating fluid between its inner and outer layers. (thefreedictionary.com)
Large cell carcinoma1
- Eight major taxa of lung carcinomas are recognized within the WHO-2004 classification: Small-cell carcinoma Squamous cell carcinoma Adenocarcinoma Large-cell carcinoma Adenosquamous carcinoma Sarcomatoid carcinoma Carcinoid Salivary gland-like carcinoma The subclassification of GCCL among these major taxa has undergone significant changes in recent decades. (wikipedia.org)
Pulmonary5
- Leukemoid reaction in pulmonary carcinoma. (biomedsearch.com)
- Leukemoid reaction with pulmonary carcinoma has been a rare observation. (biomedsearch.com)
- In an American study of a database of over 60,000 lung cancers, GCCL comprised between 0.3% and 0.4% of primary pulmonary malignancies, with an age-adjusted incidence rate of about 3 new cases per million persons per year. (wikipedia.org)
- CD44v6 expression in primary bronchioloalveolar carcinoma and conventional pulmonary adenocarcinoma. (biomedsearch.com)
- In an attempt to provide further insight into the heterogeneous appearance and behavior of bronchioloalveolar carcinomas (BACs), the pattern of CD44v6 staining in five mucinous, five nonmucinous, and eight sclerosing stage I BACs were compared with 12 comparably staged conventional pulmonary adenocarcinomas (CPAs). (biomedsearch.com)
Carcinoid Tumor1
- A few of the less common types are pleomorphic, carcinoid tumor, salivary gland carcinoma, and unclassified carcinoma. (wikipedia.org)
Sarcomatoid carcinoma1
- Elevated expression of PD-L1 by sarcomatoid carcinoma cells might account for this apparent contradiction because local inactivation of effector-immune cells through PD-1 receptor signaling could ultimately enhance the disease progression. (oncologynurseadvisor.com)
Disease8
- His research interests are adult and pediatric lung disease and the study of pediatric neoplasms. (hopkinsmedicine.org)
- Dr. Askin's research efforts are clinicopathologic studies of neoplasms and other disease processes seen by the surgical pathologist. (hopkinsmedicine.org)
- A mutation in the surfactant protein C gene associated with familial interstitial lung disease. (hopkinsmedicine.org)
- A case of Bowen's disease and small-cell lung carcinoma: long-term consequences of chronic arsenic exposure in Chinese traditional medicine. (thefreelibrary.com)
- The patient was diagnosed with Bowen's disease and developed extensive-stage small-cell carcinoma of the lung 10 years and 47 years, respectively, after the onset of arsenic exposure. (thefreelibrary.com)
- Case report: lymphoepithelial-like carcinoma of the lung-a chronic disease? (springermedizin.de)
- The patient was disease free for four years then she had primary lung recurrence which was surgically resected. (springermedizin.de)
- About 7 to 11% of patients with breast carcinoma develop a malignant pleural effusion during the course of the disease [ 3 ]. (ispub.com)
Chronic2
- We developed a method of reproducing malignant process in the lungs of rats with stimulation by chronic neurogenic pain. (medworm.com)
- In almost all rats receiving transplantation of tumor cells against the background of chronic neurogenic pain, tumor foci in the lungs were detected in 1.5-2.0 months and led to the death of the animals. (medworm.com)
Tumour1
- Tumour is on the left, obstructing the bronchus (lung). (wikipedia.org)
Clinical8
- These variants are increasingly appreciated as having different genetic, biological, and clinical properties, including prognoses and responses to treatment regimens, and therefore, that correct and consistent histological classification of lung cancers are necessary to validate and implement optimum management strategies. (wikipedia.org)
- This chapter reviews the epidemiology, the clinical presentation, and the morphologic features diagnostic of adenocarcinoma, squamous cell carcinoma, and small cell carcinoma. (springer.com)
- Lung carcinomas collected in clinical practice are used in molecular oncologic and clinicopathologic studies. (hopkinsmedicine.org)
- There are 4 clinical trials for large cell lung neuroendocrine carcinoma, of which 4 are open and 0 are completed or closed. (mycancergenome.org)
- EGFR and SSTR2 are the most frequent gene inclusion criteria for large cell lung neuroendocrine carcinoma clinical trials [ 3 ]. (mycancergenome.org)
- Nivolumab, pen-221, and etoposide are the most common interventions in large cell lung neuroendocrine carcinoma clinical trials. (mycancergenome.org)
- Expression of nuclear factor-kappa-B/P65 and fragile histidine triad in colorectal carcinoma and clinical significance thereof]. (curehunter.com)
- Clinical and biological impact of cyclin-dependent kinase subunit 2 in esophageal squamous cell carcinoma. (nih.gov)
Adenocarcinomas3
- Consequently even more research are underway to determine the useful function of genetic lab tests as predictors of responsiveness to tyrosine-kinase inhibitors.10 amplification/polysomy12 and mutations11 have already been reported in adenocarcinomas from the lung. (movd2016.org)
- Adenocarcinomas account for approximately 40% of lung cancers. (wikipedia.org)
- Novel D761Y and common secondary T790M mutations in epidermal growth factor receptor-mutant lung adenocarcinomas with acquired resistance to kinase inhibitors. (yalecancercenter.org)
Tissue8
- see neoplasm neoplasm or tumor, tissue composed of cells that grow in an abnormal way. (thefreedictionary.com)
- The lungs are made of elastic tissue filled with interlacing networks of tubes and sacs carrying air, and with blood vessels carrying blood. (thefreedictionary.com)
- a neoplasm arising in the blastema, i.e., tissue from which an organ or part is formed. (thefreedictionary.com)
- Prostate specific antigen (PSA) and prostate-specific acid phosphatase (PSAP) are expressed in benign and malignant prostatic tissue, and immunohistochemical staining for these markers is often used to confirm the prostatic origin of metastatic carcinoma. (pubmedcentralcanada.ca)
- Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified ( C25.9 ). (icd10data.com)
- Purpose: Following radiation therapy for bronchogenic carcinoma, increased FDG accumulation within the irradiated tissue can be identified. (elsevier.com)
- Conclusions: Radiation therapy occasionally causes modestly increased soft tissue FDG uptake within irradiated soft tissue in patients being treated for bronchogenic carcinoma, which persists for up to one year after therapy. (elsevier.com)
- Interstitial - involvement of the supporting tissue of the lung parenchyma resulting in fine or coarse reticular opacities or small nodules. (radiologyassistant.nl)
LCNEC1
- Large cell neuroendocrine lung carcinoma (LCNEC) is a rare, highly malignant neoplasm. (termedia.pl)
Papillary2
- True papillary carcinoma of the lung: a distinct clinicopathologic entity. (hopkinsmedicine.org)
- This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. (fishersci.com)
Bronchioloalveolar1
- Bronchioloalveolar adenocarcinoma (BAC) is a subtype of lung adenocarcinoma characterized by malignant cell growth occurring in the alveolar septa. (visualdx.com)
Diseases3
- Occupational Lung Diseases. (cdc.gov)
- He and his team also see material from a wide spectrum of non-neoplastic interstitial lung diseases. (hopkinsmedicine.org)
- These diseases, especially dermatomyositis, have a well-known association with a wide variety of neoplasms including lung, breast, ovary and colon cancers. (pubmedcentralcanada.ca)
Bronchial2
- In general, most lung cancers arise from the bronchial epithelium (giving the generic term 'bronchiogenic carcinoma') and are most commonly found around the hilium of the lung (ex. (brainscape.com)
- There should be evidence of reexpansion of the lung after the drainage without evidence of bronchial obstruction or fibrotic trapped lung. (ispub.com)
Bronchoalveolar2
- The new name for BAC - bronchoalveolar carcinoma is adenocarcinoma in situ. (radiologyassistant.nl)
- Lung neoplasms like bronchoalveolar carcinoma and lymphoma. (radiologyassistant.nl)
EGFR5
- Somatic mutations in the TP53 , EGFR , and KRAS genes are common in lung cancers. (medlineplus.gov)
- the gene the incident of amplification as well as the EGFR appearance in adenoid cystic carcinomas and mucoepidermoid carcinomas from the lung. (movd2016.org)
- These pathways complement our catalog of research reagents for the study of Non-small Cell Lung Carcinoma including antibodies and ELISA kits against EGFR, TP53, VEGFA, MID1, CDKN2A. (novusbio.com)
- The enhanced activity of the EGFR due to over-expression, co-expression of the receptor and its ligands, as well as activating mutations is the hallmark of many human carcinomas. (sigmaaldrich.com)
- In many types of tumor, including lung, breast, prostate, ovary, gastrointestinal tract and brain, the EGFR receptor is expressed approximately 100 times the normal number of EGF receptors found on the surface of normal cells. (sigmaaldrich.com)
Cell carcinomas1
- Giant-cell carcinomas have been reported to be diagnosed in a significantly younger population than all non-small-cell carcinomas considered as a group. (wikipedia.org)
Tumor cells2
- Giant cell carcinoma is a non-small cell carcinoma solely comprising anaplastic, giant tumor cells (Figure 2, D). (thefreedictionary.com)
- Detection of circulating rare cells (CRCs), including both CTCs and CECs, is the most representative of liquid biopsy due to its unique availability of frequent and non-invasive detecting tumor cells in carcinoma patients. (mdpi.com)
Poorly differentiated squamous3
- Seventeen cases of this tumor located exclusively in the mouth were compared to 26 cases of poorly differentiated squamous cell carcinoma and 28 cases of well to moderately differentiated squamous cell carcinoma matched by stage and tumor site. (biomedcentral.com)
- For groups poorly differentiated squamous cell carcinoma and basaloid squamous cell carcinoma, reduction or absence of E-cadherin staining was observed in more than 80.0% of carcinomas, and it was statistically significant compared to well to moderately differentiated squamous cell carcinoma (p = .019). (biomedcentral.com)
- A strong expression of β-catenin was observed in 26.9% and 20.8% of well to moderately differentiated squamous cell carcinoma and poorly differentiated squamous cell carcinoma, respectively, and in 41.2% of basaloid squamous cell carcinoma. (biomedcentral.com)
Primary and metastatic1
- A variety of primary and metastatic neoplasms can involve the anterior mediastinum and have similar radiographic or histologic appearances. (semanticscholar.org)
Breast Carcinomas1
- Reports of prostate specific antigen (PSA) expression in male and female breast carcinomas[ 3 , 10 - 15 ] have raised questions about the value of PSA staining in differentiating metastatic prostatic carcinoma from primary breast carcinoma. (pubmedcentralcanada.ca)
Myeloproliferative neoplasms1
- This presentation is prepared for undergraduate students about the various myeloproliferative neoplasms with updated information. (slideshare.net)
Prostate carcinoma1
- PSA and PSAP are useful markers to distinguish primary breast carcinoma from prostate carcinoma metastatic to the male breast. (pubmedcentralcanada.ca)