The interaction of rhodium(II) carboxylates with enzymes. (1/1023)The effect of rhodium(II) acetate, propionate, and methoxyacetate on the activity of 17 enzymes was evaluated. The enzymes were preincubated with the rhodium(II) complexes in order to detect irreversible inhibition. All enzymes that have essential sulfhydryl groups in or near their active site were found to be irreversibly inhibited. Those enzymes without essential sulfhydryl groups were not affected. In each case, the rate of inactivation closely paralleled the observed toxicity and antitumor activity of rhodium(II) carboxylates; that is, rhodium(II) propionate greater than rhodium(II) acetate greater than rhodium(II) methoxyacetate. In addition, those enzymes that have been demonstrated to be most sensitive to established sulfhydryl inhibitors, such as glyceraldehyde-3-phosphate dehydrogenase, were also most sensitive to rhodium(II) carboxylate inactivation. Proton nuclear magnetic resonance measurements made during the titration of rhodium(II) acetate with cysteine showed that breakdown of the carboxylate cage occurred as a result of reaction with this sulfhydryl-containing amino acid. (+info)
Action of partially thiolated polynucleotides on the DNA polymerase alpha from regenerating rat liver. (2/1023)The effects of partially thiolated polynucleotides on the DNA polymerase alpha from regenerating rat liver were investigated. The enzyme was isolated from the nuclear fraction essentially according to the method of Baril et al.; it was characterized as the alpha polymerase on the basis of its response to synthetic templates and its inhibition with N-ethylmaleimide. Although polycytidylic acid had no effect on the DNA polymerase alpha either as a template or as an inhibitor, partially thiolated polycytidylic acid (MPC) was found to be a potent inhibitor, its activity being directly related to its extent of thiolation (percentage of 5-mercaptocytidylate units in the polymer). In comparison, the DNA polymerase beta which was purified from normal rat liver nuclear fraction, was much less sensitive to inhibition by MPC. Analysis of the inhibition of the alpha polymerase by the method of Lineweaver and Burk showed that the inhibitory action of MPC was competitively reversible with the DNA template, but the binding of the 7.2%-thiolated MPC to the enzyme was much stronger than that of the template (Ki/Km less than 0.03). Polyuridylic acid as such showed some inhibitory activity which increased on partial thiolation, but the 8.4%-thiolated polyuridylic acid was less active than the 7.2% MPC. When MPC was annealed with polyinosinic acid, it lost 80% of its inhibitory activity in the double-stranded configuration. However, 1 to 2%-thiolated DNA isolates were significantly more potent inhibitors than were comparable (1.2%-thiolated) MPC and showed competitive reversibility with the unmodified (but "activated") DNA template. These results indicate that the inhibitory activities of partially thiolated polynucleotides depend not only on the percentage of 5-mercapto groups but also on the configuration, base composition, and other specific structural properties. (+info)
Human colon adenocarcinomas express a MUC1-associated novel carbohydrate epitope on core mucin glycans defined by a monoclonal antibody (A10) raised against murine Ehrlich tumor cells. (3/1023)A monoclonal antibody (mAb; A10) raised against murine Ehrlich tumor cell surface carbohydrates was tested for reactivity with human normal and malignant tissues. A10 reacted strongly, with a high proportion of adenocarcinomas arising from colon and other tissues but not with breast carcinomas or other malignant tumors. Normal tissues were virtually A10 unreactive, except for the duct cells from breast and pancreas and some bronchial mucosae. Ultrastructural studies showed mAb A10 immunolabeling of both microvilli and mucin droplets in colon cancer cells but not in normal absorptive or globet cells. A10 reacted strongly with mucin-enriched fractions from colon cancer tissues and HT-29 xenografts but not from normal colon tissues. A10 epitope was carried on MUC1 derived from colon adenocarcinomas and probably on other mucin species, although not on MUC2 molecules. A10 epitope was resistant to exoglycosidases and periodate oxidation but sensitive to the Smith's degradation and beta-elimination, suggesting the involvement of O-linked carbohydrates in nonterminal reducing positions. A mucin-type glycosidic linkage was supported because of the lack of A10 reactivity with HT-29 cells grown with phenyl-N-acetyl-alpha-D-galactosaminide. Deglycosylation studies with trifluoromethanesulfonic acid pointed to the involvement of core mucin glycans in the A10 epitope. This epitope was resistant to protease, O- and N-glycanase treatments carried out on trifluoromethanesulfonic acid-deglycosylated mucins. Inhibition studies with core 1, core 2, core 3, and core 6 suggested the latter [GlcNAcbeta(1-6)GalNAc] as being involved in A10 epitope. Taken together, the present results point to A10 defining a core 6-related epitope on core mucin glycans expressed by colon cancer MUC1 not previously associated with human cancer. (+info)
Phospholipid metabolism in ehrlich ascites tumor cells. II. Turnover rate of ether phospholipids. (4/1023)1. Radioactive precursors of phospholipids, i.e., 32Pi, [1-14C]glycerol, [2-3H]glycerol, and [1-14C]acetate, were individually injected into the peritoneal cavity of mice bearing Ehrlich ascites tumor cells and the rates of incorporation were estimated. 2. Although [2-3H]glycerol was not practically incorporated into ether phospholipids, the other three radioactive precursors were incorporated into diacyl, 1-O-alkenyl-2-acryl-, and 1-O-alkyl-2-acryl-GPE (GPC). 3. In the experiments on 32Pi or [1-14C]acetate incorporation, 1-O-alkyl compounds in the ethanolamine phosphoglyceride fraction showed high specific activities in comparison with 1-acyl compounds. In the case of [1-14C]glycerol incorporation, a high rate of incorporation into 1-O-alkyl compounds was not found. In the choline phosphoglyceride fraction, a high rate of incorporation of the above precursors into 1-O-alkyl compounds was not observed. 4. The specific activities of 1-O-alkenyl compounds were fairly low compared with those of 1-acyl- and 1-O-acyl- and 1-O-alkyl compounds throughout the incorporation experiments with [1-14C]glycerol and [1-14C]acetate, but in 32Pi incorporation, 1-O-alkenyl compounds showed higher specific activities than 1-acyl compounds in ethanolamine phosphoglyceride, suggesting an exchange reaction of the phosphorylethanolamine moiety. 5. From the above findings, it appears that alkyl ether phospholipids of ethanolamine from may have a significant role in ascites tumor cells, based on their rapid turnover. (+info)
Isolation of ekatetrone, a new metabolite of producing variants of Streptomyces aureofaciens. (5/1023)From a mixture of substances formed by producing strains of Streptomyces aureofaciens under conditions of submerged fermentation a new metabolite, ekatetrone, was isolated. Its isolation and basic physical and chemical data are described. Ekatetrone is a quinone derivative with a carboxamide group. In tests in vitro with cells of Ehrlich's ascites tumour evidence was provided that ekatetrone inhibits proteo- and nucleosynthesis. (+info)
New semisynthetic vinca alkaloids: chemical, biochemical and cellular studies. (6/1023)A new semisynthetic anti-tumour bis-indol compound, KAR-2 [3'-(beta-chloroethyl)-2',4'-dioxo-3,5'-spiro-oxazolidino-4-dea cetoxy-vinblastine] with lower toxicity than vinca alkaloids used in chemotherapy binds to calmodulin but, in contrast to vinblastine, does not exhibit anti-calmodulin activity. To investigate whether the modest chemical modification of bis-indol structure is responsible for the lack of anti-calmodulin potency and for the different pharmacological effects, new derivatives have been synthesized for comparative studies. The synthesis of the KAR derivatives are presented. The comparative studies showed that the spiro-oxazolidino ring and the substitution of a formyl group to a methyl one were responsible for the lack of anti-calmodulin activities. The new derivatives, similar to the mother compounds, inhibited the tubulin assembly in polymerization tests in vitro, however their inhibitory effect was highly dependent on the organization state of microtubules; bundled microtubules appeared to be resistant against the drugs. The maximal cytotoxic activities of KAR derivatives in in vivo mice hosting leukaemia P388 or Ehrlich ascites tumour cells appeared similar to that of vinblastine or vincristine, however significant prolongation of life span could be reached with KAR derivatives only after the administration of a single dose. These studies plus data obtained using a cultured human neuroblastoma cell line showed that KAR compounds displayed their cytotoxic activities at significantly higher concentrations than the mother compounds, although their antimicrotubular activities were similar in vitro. These data suggest that vinblastine/vincristine damage additional crucial cell functions, one of which could be related to calmodulin-mediated processes. (+info)
Heterogeneity of native ribosomal 60-S subunits in Ehrlich ascites tumor cells cultured in vitro. (7/1023)Native large ribosomal subunits in cultured Ehrlich ascites tumor cells analyzed by high-resolution CsCl isopycnic centrifugation consist of at least two classes of particles with densities of 1.57 g/cm3 (LI) and 1.59 g/cm3 (LII), respectively. A wash with 0.5 M KCl converts LI into particles with the density of LII particles. Incubation of derived large subunits (density 1.59 g/cm3) with 0.5 M KCl wash of reticulocyte ribosomes leads to the formation of particles with the density of LI particles. A protein with a molecular weight of 57000 present in the high-KCl wash of 60-S native subunits was virtually absent in the KCl wash of 40-S subunits or polyribosomes suggesting that specific protein factors may be present on some native 60-S subunits. Possible functions of these protein factors are discussed. (+info)
Glyceraldehyde-3-phosphate dehydrogenase from Ehrlich ascites carcinoma cells its possible role in the high glycolysis of malignant cells. (8/1023)Glyceraldehyde-3-phosphate dehydrogenase has been purified to apparent homogeneity from Ehrlich ascites carcinoma (EAC) cells. The enzyme is quite active over a pH range of 7.5-9.0 with an optimum pH of 8.4-8.7. The specific activity of the enzyme is much higher than that from other normal sources. In contrast to enzyme obtained from rabbit muscle, the EAC cell enzyme is not significantly inhibited by physiological concentrations of ATP at physiological pH. Kinetic studies using different substrates and inhibitors indicate that the properties of the EAC cell enzyme are significantly different from those of glyceraldehyde-3-phosphate dehydrogenase obtained from other normal sources. The striking dissimilarity of the malignant cell glyceraldehyde-3-phosphate dehydrogenase compared with this enzyme from other normal sources, particularly in respect to the interaction with ATP, may in part explain the high glycolysis of malignant cells. (+info)
B-1 cells and concomitant immunity in Ehrlich tumour progression
Concomitant immunity is a phenomenon in which a tumour-bearing host is resistant to the growth of an implanted secondary tumour. Metastases are considered to be secondary tumours that develop spontaneously during primary tumour growth, suggesting the involvement of concomitant immunity in controlling the rise of metastases. It has been demonstrated that B-1 cells, a subset of B-lymphocytes found predominantly in pleural and peritoneal cavities, not only increase the metastatic development of murine melanoma B16F10, but also are capable of differentiating into mononuclear phagocytes, modulating inflammatory responses in wound healing, in oral tolerance and in Paracoccidiose brasiliensis infections. Here, we studied B-1 cells participation in concomitant immunity during Ehrlich tumour progression. Our results show that B-1 cells obtained from BALB/c mice previously injected with Ehrlich tumour in the footpad were able to protect BALB/c and BALB/Xid mice against Ehrlich tumour challenge. in ...
ORBi: Browsing ORBi
in European Journal of Cell Biology (1988), 47(2), 346-57. In order to investigate the DNA localization within Ehrlich tumor cell nucleoli during mitosis, two recent immunocytochemical methods using either an anti-DNA or an anti-bromodeoxyuridine (BrdU ... [more ▼]. In order to investigate the DNA localization within Ehrlich tumor cell nucleoli during mitosis, two recent immunocytochemical methods using either an anti-DNA or an anti-bromodeoxyuridine (BrdU) monoclonal antibody have been applied. In both cases, the immunogold labeling has been performed on ultrathin sections of cells embedded either in Lowicryl K4M or in Epon, respectively. Identical results are observed with both immunocytochemical approaches. In the interphase nucleolus, besides the labeling of the perinucleolar chromatin shell and of its intranucleolar invaginations which penetrate into the nucleolar body and often terminate at the fibrillar centers, a few gold particles are also preferentially found towards the peripheral ...
AID 118144 - Effect of compound on Ehrlich ascites carcinoma growth in CF1 mice at a dose ((20 mg/kg)/day) ip survival at day 9...
BioAssay record AID 118144 submitted by ChEMBL: Effect of compound on Ehrlich ascites carcinoma growth in CF1 mice at a dose ((20 mg/kg)/day) ip survival at day 9 packed cell volume as a percent.
Isolation of Nucleoli from Ehrlich Ascites Tumor Cells and Dynamics of Nascent RNA within Isolated Nucleoli. - Thiry Marc
en] Here we describe a new, rapid method for isolating nucleoli from Ehrlich tumor cells that preserves their morphological integrity and high transcriptional activity. Until now, methods for isolation of nucleoli were generally assumed to empty one of their three main compartments, the fibrillar center, of its contents. This new method consists of sonicating cells in an isotonic medium containing MgSO(4), spermidine, and spermine, followed by separation of nucleoli through a Percoll density gradient. Using the nonisotopic approach of labelling with BrUTP, we have further investigated the dynamics of nascent ribosomal RNAs (rRNAs) within morphologically intact isolated nucleoli at the electron microscope level. We show that ribosomal transcripts are elongated in the cortex of the fibrillar center and then enter the surrounding dense fibrillar component ...
Ca2+ translocation in Ehrlich ascites tumor cells - Semantic Scholar
Ca2+ uptake into Ehrlich ascites tumor cells was studied at 0°C in the presence of mitochondrial inhibitors, conditions that minimized complications caused by sequestration of Ca2+ into organelles or by excretion. Under these conditions Ruthenium Red inhibited Ca2+ uptake, but other previously implicated ions, such as Pi or Mg2+, had no effect. Valinomycin either inhibited or slightly stimulated Ca2+ uptake depending on the presence of excess K+ on the outside or inside of the cell, respectively. Nigericin inhibited Ca2+ transport. Based on these data we propose an electrogenic uptake of Ca2+, possibly via a Ca2+/H+ antiport mechanism. The observation that glucose inhibited Ca2+ uptake suggested that in Ehrlich ascites tumor cells an energy-driven Ca2+ expulsion mechanism is operative, similar to that in erythrocytes. Plasma membrane preparations of ascites tumor cells were found to contain a Ca2+-dependent ATPase. These preparations, when incorporated into liposomes in an inside-out orientation,
Inhibition of Pruine Phosphoribosyltransferases of Ehrlich Ascites-tumour Cells by 6-mercaptopurine. - Semantic Scholar
1. The formation of adenosine 5-phosphate, guanosine 5-phosphate and inosine 5-phosphate from [8-(14)C]adenine, [8-(14)C]guanine and [8-(14)C]hypoxanthine respectively in the presence of 5-phosphoribosyl pyrophosphate and an extract from Ehrlich ascites-tumour cells was assayed by a method involving liquid-scintillation counting of the radioactive nucleotides on diethylaminoethylcellulose paper. The results obtained with guanine were confirmed by a spectrophotometric assay which was also used to assay the conversion of 6-mercaptopurine and 5-phosphoribosyl pyrophosphate into 6-thioinosine 5-phosphate in the presence of 6-mercaptopurine phosphoribosyltransferase from these cells. 2. At pH 7.8 and 25 degrees the Michaelis constants for adenine, guanine and hypoxanthine were 0.9 mum, 2.9 mum and 11.0 mum in the assay with radioactive purines; the Michaelis constant for guanine in the spectrophotometric assay was 2.6 mum. At pH 7.9 the Michaelis constant for 6-mercaptopurine was 10.9 mum. 3. 25 mum-6
Effets de la dihydroflavopéreirine et de la sempervirine (alacaloïdes dérivés de la beta-carboline) sur des cellules...
en] The cellular effects of dihydroflavopereirine and sempervirine ( two alkaloids isolated from Loganiaceae) are analysed by cytological methods in experimental tumours cultivated in vitro ( B16 mouse melanoma cells, mouse Ehrlich tumour cells ELT). Under some experimental conditions, a certain degree of antimitotic activity is demonstrated and related to the molecular structure ...
A comparison of the cytidine 5′-diphosphate (CDP) and adenosine 5′-diphosphate (ADP) reductase activities from Ehrlich tumor cells was made to determine if the properties of the enzyme for these substrates were the same, except for the allosteric effector. It was observed that various purification steps did not result in an enzyme fraction that had a constant ratio of CDP:ADP reductase activities. The optimal Mg2+ ion concentration for CDP reduction was 3 to 4 mm, while the optimal Mg2+ ion concentration for ADP reduction was 0.1 mm. Concentrations of Mg2+ ions greater than 0.1 mm inhibited ADP reduction. CDP reduction was relatively insensitive to the presence of dimethylformamide or dimethyl sulfoxide in the reaction mixture, but ADP reduction was decreased in the presence of these two compounds. Periodate-oxidized adenosine 5′-monophosphate, on incubation with the enzyme, had a greater effect on CDP reduction but little or no effect on ADP reduction. The response of the CDP and ADP ...
Detection of DNA cross-links in tumor cells with the ethidium bromide fluorescence assay - Research database - University of...
Until now the fluorescence assay with ethidium bromide has only been used on pure DNA. This assay depends on the difference in fluorescence between single- and double-stranded DNA (dsDNA). Cross-links in DNA are measured by the return of fluorescence of dsDNA after heat denaturation at pH 12. Under these conditions denatured DNA gives very low fluorescence. In the present study this assay was applied to tumor cells. The mouse Ehrlich ascites tumor cell line (EAT) and a human small-cell carcinoma line (GLC4) were incubated for 4 hr at 37 degrees C, with the cross-linking agent cis-diamino-dichloro platinum (cDDP). The samples of whole cells were thereafter resuspended in potassium phosphate buffer with 10 mM EDTA, 4M NaCl, 0.1% Sarkosyl pH 7.2, for 16 hr at 37 degrees C. Measurements were performed with a spectrofluorometer with excitation wavelength 525 nm, emission wavelength 580 nm. There was a linear relationship for cDDP concentrations of 0-150 microM and the extent of DNA cross-links in EAT ...
Revealing the anticancer properties of fluoroacetate.
INTRODUCTION: Fluoroacetate (FA) is a highly toxic metabolic poison found in eight species of plants - including Dichapetalum and Gastrolobium - growing in Australia, South and Central Africa and South America. The level of FA in some plants can reach up to 5 g kg-1 dry weight and can cause death of livestock and domestic animals. Moreover, FA can be found in fog and rain-drops in some industrial regions. The best known representative of FA is its sodium salt (SFA, compound 1080), which is used in several countries for controlling populations of some vertebrates. Although extremely toxic, FA has positive properties: it can prevent development of tolerance to morphine, and has radioprotective power due to its capacity to reduce body temperature and oxygen consumption. OBJECTIVES: To evaluate the antitumor properties of SFA in monotherapy regime and in combination with a known antitumor compound. MATERIALS AND METHODS: Mice bearing Ehrlich tumor carcinoma were treated daily with SFA, 1.25mg/kg ...
A novel kefir product (PFT) inhibits Ehrlich ascites carcinoma in mice via induction of apoptosis and immunomodulation* | BMC...
The popularity of fermented foods such as kefir, kuniss, and tofu has been greatly increasing over the past several decades, and the ability of probiotic bacteria to exert anticancer effects has recently become the focus of research. While we have recently demonstrated the ability of the novel kefir product PFT (Probiotics Fermentation Technology) to exert anticancer effects in vitro, here we demonstrate its ability to inhibit Ehrlich ascites carcinoma (EAC) in mice. Mice were inoculated intramuscularly with EAC cells to develop solid tumors. PFT was administered orally (2 g/kg/day) to mice 6 days/week, either 2 days before tumor cell inoculation or 9 days after inoculation to mice bearing solid tumors. Tumor growth, blood lymphocyte levels, cell cycle progression, apoptosis, apoptotic regulator expression, TNF-α expression, changes in mitochondrial membrane potential (MMP), PCNA, and CD4+ and CD8+ T cells in tumor cells were quantitatively evaluated by flow cytometry or RT-PCR. Further studies in
The membrane potential of ehrlich ascites tumor cells, microelectrode by U Lassen, A Nielsen et al.
Lassen, U; Nielsen, A; Pape, L; and Simonsen, L, The membrane potential of ehrlich ascites tumor cells, microelectrode measurements and their critical evaluation. (1971). Subject Strain Bibliography 1971. 2022 ...
Inorganic phosphate in ehrlich ascites tumor cells and its distributio by L O. Simonsen and F Cornelius
Simonsen, L O. and Cornelius, F, Inorganic phosphate in ehrlich ascites tumor cells and its distribution across the cell membrane. (1978). Subject Strain Bibliography 1978. 3326 ...
Antitumor Activity of Citrus maxima (Burm.) Merr. Leaves in Ehrlichs Ascites Carcinoma Cell-Treated Mice
Context. The plant Citrus maxima Merr. (Rutaceae), commonly known as shaddock or pomelo is indigenous to tropical parts of Asia. The objective of present study is to evaluate the methanol extract of Citrus maxima leaves for its antitumor activity against Ehrlichs Ascites Carcinoma cell in Swiss alb …
Treatment of the 1-day-old Ehrlich ascites tumor with combinations of selected doses of l-asparaginase and the l-glutamine antagonist, 6-diazo-5-oxo-l-norleucine, or of the l-glutamine acid antagonist, dl-methionine-dl-sulfoximine, produced significantly more growth inhibition without a marked increase in host toxicity than did treatment with l-asparaginase administered alone. In the 3-day-old tumor treated with the combination of l-asparaginase and 6-diazo-5-oxo-l-norleucine, there was a significant enhancement of growth inhibition as compared with the effect of either drug used alone. A less significant increase of growth inhibition was obtained with combination of l-asparaginase and l-glutamyl-γ-hydrazide as compared with the effect of this chemical administered alone.. Combinations of l-asparaginase and 6-diazo-5-oxo-l-norleucine produced increased antitumor effects in mouse melanoma B16 and to a lesser degree in the solid form of Ehrlich tumor and Walker carcinosarcoma 256 of the ...
N-Bromoacetyl-β-D-glucosamine tetra-O-acetate and N-bromoacetyl-β-D-galactosamine tetra-O-acetate as chemotherapeutic agents...
TY - JOUR. T1 - N-Bromoacetyl-β-D-glucosamine tetra-O-acetate and N-bromoacetyl-β-D-galactosamine tetra-O-acetate as chemotherapeutic agents with immunopotentiating effects in Ehrlich ascites tumor-bearing mice. AU - Simon, P.. AU - Burlingham, W. J.. AU - Conklin, R.. AU - Fondy, Thomas P. PY - 1979. Y1 - 1979. N2 - N-Bromoacetyl-β-D-glucosamine tetra-O-acetate (NBrAcGlc-TA) and N-bromoacetyl-β-D-galactosamine tetra-O-acetate (NBrAcGal-TA) produced strong in vitro cytotoxicity against both Ehrlich and L1210 leukemia dividing cell lines at μM concentrations. A single administration i.p. at one-half the dose lethal to 10% of the animals of either agent cured 85% of Ehrlich ascites tumor-bearing C57BL/6J x DBA/2 (hereafter called B6D2F1) mice. Animals immunosuppressed by prior X-irradiation could not be cured by these agents. The corresponding chloro and fluoroderivatives and the non-O-acetylated N-haloacetylhexosamines were inactive in vitro and in vivo. No significant effect against L1210 ...
Cv Lettre Motivation Cv Lettre Motivation Cv Lettre Motivation - All New Resume Examples & Resume Template
Cv Lettre Motivation Cv Lettre Motivation Cv Lettre Motivation Wiring Diagram Online,cv lettre motivation cv lettre motivation cv lettre motivation wiring diagram basics, cv lettre motivation cv lettre motivation cv lettre motivation wiring diagram maker, create cv lettre motivation cv lettre motivation cv lettre motivation wiring diagram,
Regulation of glutathione metabolism in Ehrlich ascites tumour cells | Biochemical Journal
Glutathione metabolism was studied in cancer cells during the growth of an Ehrlich ascites tumour. GSH, but not GSSG, content decreases when cell proliferation and the rate of protein synthesis in the tumour decrease. This change correlates with a decrease in the rate of GSH synthesis and an increase in glutathione peroxidase and glutathione S-transferase activities. Glutathione efflux from tumour cells seems to co-ordinate with the rate of GSH synthesis. Cysteine, and not methionine, promotes GSH synthesis in tumour cells. However, changes in the rate of GSH synthesis are not due to limitations in the supply of blood cysteine or to changes in the intracellular amino acid pool of the cancer cells. Our data suggest that changes in protein metabolism accompanying tumour growth in vivo can modulate glutathione content in cancer cells. ...
Interferon enhances protein degradation in Ehrlich ascites-tumour cells | Biochemical Society Transactions
Thank you for your interest in spreading the word about Biochemical Society Transactions.. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.. ...
Search Results - - 9,063 Results - UNT Digital Library
Description: Enzyme fractions were isolated from Ehrlich ascites cells which introduced methyl groups into methyl deficient rat liver mRNA and unmethylated vaccinia mRNA. The methyl groups were incorporated at the 5' end into cap 1 structures by the viral enzyme, whereas both cap 0 and cap 1 structures were formed by the Ehrlich ascites cell enzymes. Preliminary results indicate the presence of adenine N/sup 6/-methyltransferase activity in Ehrlich ascites cells. These results indicate that mRNA deficient in 5'-cap methylation and in internal methylation of adenine accumulated in rats on exposure to ethionine. The methyl-deficient mRNA isolated from the liver of ethionine-fed rats differed in its translational properties from mRNA isolated from control animals. Preliminary experiments indicate that single topical application of 17n moles of TPA to mouse skin altered tRNA methyltransferases. The extent of methylation was increased over 2-fold in mouse skin treated with TPA for 48 hours. ...
Safe Combination of Cisplatin and Metformin Reverts the Malignant Ascites in a Mouse Model to a Solid Tumor by Downregulation...
Background: Currently, combination therapy has become the cornerstone of cancer treatment. The combination of different anti-cancer mechanisms can induce tumor cell quiescence. However, toxicity to normal tissue is the major limitation of existing combined drugs. Method: In this experimental study, Ehrlich ascites carcinoma inoculated into mice was targeted with just one dose of cisplatin and later doses of metformin, a safe anti-diabetic drug with an anti-cancer effect, to maintain Ehrlich ascites carcinoma (EAC) cells in the quiescent state and secure a longer survival time without tumor recurrence. Results: The group that underwent dual therapy developed a delayed solid tumor instead of a malignant ascites. The induction of chemo-quiescence in the EAC cells was proven by the downregulation of mechanistic target of rapamycin and the upregulation of cyclin-dependent kinase inhibitor 1 (p21) expressions. Intriguingly, the conversion of free neoplastic cells into a solid tumor was associated with a
Lettre De Motivation Format Mod U00e8le Pr U00e9sentation Lettre De - All New Resume Examples & Resume Template
Lettre De Motivation Format Mod U00e8le Pr U00e9sentation Lettre De Wiring Diagram Online,lettre de motivation format mod u00e8le pr u00e9sentation lettre de wiring diagram basics, lettre de motivation format mod u00e8le pr u00e9sentation lettre de wiring diagram maker, create lettre de motivation format mod u00e8le pr u00e9sentation lettre de wiring diagram,
Lettre Au Maire Pour Envoyer Cv Et Lettre De Motivation - All New Resume Examples & Resume Template
Lettre Au Maire Pour Envoyer Cv Et Lettre De Motivation Wiring Diagram Online,lettre au maire pour envoyer cv et lettre de motivation wiring diagram basics, lettre au maire pour envoyer cv et lettre de motivation wiring diagram maker, create lettre au maire pour envoyer cv et lettre de motivation wiring diagram,
Modele Lettre De Motivation Aide Soignante Luxury 8 Lettre - All New Resume Examples & Resume Template
Modele Lettre De Motivation Aide Soignante Luxury 8 Lettre Wiring Diagram Online,modele lettre de motivation aide soignante luxury 8 lettre wiring diagram basics, modele lettre de motivation aide soignante luxury 8 lettre wiring diagram maker, create modele lettre de motivation aide soignante luxury 8 lettre wiring diagram,
Evaluation of intraperitoneal vincristine in malignant peritoneal effusion - Manipal Academy of Higher Education, Manipal,...
TY - JOUR. T1 - Evaluation of intraperitoneal vincristine in malignant peritoneal effusion. AU - Bairy, K. L.. AU - Sanath, S.. AU - Jagetia, G. C.. AU - Somayaji, S. N.. AU - Vidyasagar, M. S.. AU - Baliga, M. S.. PY - 2003/1/1. Y1 - 2003/1/1. N2 - The efficacy and safety of intraperitoneal administration of vincristine sulphate was determined in mice bearing Ehrlich ascitic carcinoma. The tumor bearing animals were administered with 0.5 mg/kg body weight (b.wt) of freshly prepared vincristine sulphate intraperitoneally on day 6 after tumor transplantation followed by drug administration once daily 5 days a week consecutively. The observations regarding the survival, alteration in the volume of peritoneal fluid, increase in life span and pathological changes in the liver, kidney, gastrointestinal tract and bone tissues were made. The vincristine sulphate treatment reduced the malignant cell population significantly and there were no significant changes in the histological picture of liver, ...
Robert L. Ehrlich, Jr. form letter to constituent, Fall 1991 - Quartex site
Robert L. Ehrlich, Jr. form letter to constituent, Fall 1991, rle010412, Form response letter from Robert L. Ehrlich, Jr. to a constituent regarding the 1992 budget deficit, sales taxes, proposed State Trooper cuts, proposed MEDEVAC and DDA reductions, and general state spending priorities., Budget -- Maryland, Ehrlich, Bob, 1957- -- Correspondence, Emergency medical services -- Maryland, Maryland State Police, Taxation -- Law and legislation -- Maryland, English, Robert L. Ehrlich, Jr. Collection for Public Leadership Studies, The enclosed materials mentioned in the letter are not included in this copy of the document., 2 pages, The names and addresses of private citizens have been hidden from public view on items of correspondence out of respect for the individuals privacy., Donated by the Honorable Robert L. Ehrlich, Jr., Series 1: Documents. Subseries 1: Correspondence;, This record has been cataloged according to Dublin Core, Describing Archives: A Contents Standard, and local standards.
Exemple De Lettre De Motivation Pour Un Stage De Seconde - All New Resume Examples & Resume Template
Exemple De Lettre De Motivation Pour Un Stage De Seconde Wiring Diagram Online,exemple de lettre de motivation pour un stage de seconde wiring diagram basics, exemple de lettre de motivation pour un stage de seconde wiring diagram maker, create exemple de lettre de motivation pour un stage de seconde wiring diagram,
Corps De Mail Envoie Lettre De Motivation Et Cv - All New Resume Examples & Resume Template
Corps De Mail Envoie Lettre De Motivation Et Cv Wiring Diagram Online,corps de mail envoie lettre de motivation et cv wiring diagram basics, corps de mail envoie lettre de motivation et cv wiring diagram maker, create corps de mail envoie lettre de motivation et cv wiring diagram,
Cv Et Lettre De Motivation En Classe De Fle - All New Resume Examples & Resume Template
Cv Et Lettre De Motivation En Classe De Fle Wiring Diagram Online,cv et lettre de motivation en classe de fle wiring diagram basics, cv et lettre de motivation en classe de fle wiring diagram maker, create cv et lettre de motivation en classe de fle wiring diagram,
Exemple De Cv Et Lettre De Motivation En Anglais - All New Resume Examples & Resume Template
Exemple De Cv Et Lettre De Motivation En Anglais Wiring Diagram Online,exemple de cv et lettre de motivation en anglais wiring diagram basics, exemple de cv et lettre de motivation en anglais wiring diagram maker, create exemple de cv et lettre de motivation en anglais wiring diagram,
Exemple De Cv Et Lettre De Motivation Pour Job Dete - All New Resume Examples & Resume Template
Exemple De Cv Et Lettre De Motivation Pour Job Dete Wiring Diagram Online,exemple de cv et lettre de motivation pour job dete wiring diagram basics, exemple de cv et lettre de motivation pour job dete wiring diagram maker, create exemple de cv et lettre de motivation pour job dete wiring diagram,
Il Faudra Mettre La Lettre De Motivation Avant Le Cv - All New Resume Examples & Resume Template
Il Faudra Mettre La Lettre De Motivation Avant Le Cv Wiring Diagram Online,il faudra mettre la lettre de motivation avant le cv wiring diagram basics, il faudra mettre la lettre de motivation avant le cv wiring diagram maker, create il faudra mettre la lettre de motivation avant le cv wiring diagram,
Exemple De Lettre De Motivation Pour Les Espace Vert - All New Resume Examples & Resume Template
Exemple De Lettre De Motivation Pour Les Espace Vert Wiring Diagram Online,exemple de lettre de motivation pour les espace vert wiring diagram basics, exemple de lettre de motivation pour les espace vert wiring diagram maker, create exemple de lettre de motivation pour les espace vert wiring diagram,
Cv Lettre De Motivation Armee Terre Combattant De Linfanterie - All New Resume Examples & Resume Template
Cv Lettre De Motivation Armee Terre Combattant De Linfanterie Wiring Diagram Online,cv lettre de motivation armee terre combattant de linfanterie wiring diagram basics, cv lettre de motivation armee terre combattant de linfanterie wiring diagram maker, create cv lettre de motivation armee terre combattant de linfanterie wiring diagram,
Offre Pole Emploi Sans Cv Et Lettre De Motivation - All New Resume Examples & Resume Template
Offre Pole Emploi Sans Cv Et Lettre De Motivation Wiring Diagram Online,offre pole emploi sans cv et lettre de motivation wiring diagram basics, offre pole emploi sans cv et lettre de motivation wiring diagram maker, create offre pole emploi sans cv et lettre de motivation wiring diagram,
Letttre Ecrite Accompagne Dun Cv Et Lettre De Motivation - All New Resume Examples & Resume Template
Letttre Ecrite Accompagne Dun Cv Et Lettre De Motivation Wiring Diagram Online,letttre ecrite accompagne dun cv et lettre de motivation wiring diagram basics, letttre ecrite accompagne dun cv et lettre de motivation wiring diagram maker, create letttre ecrite accompagne dun cv et lettre de motivation wiring diagram,
Jenvoie En Pieces Jointes Cv Et Lettre De Motivation - All New Resume Examples & Resume Template
Jenvoie En Pieces Jointes Cv Et Lettre De Motivation Wiring Diagram Online,jenvoie en pieces jointes cv et lettre de motivation wiring diagram basics, jenvoie en pieces jointes cv et lettre de motivation wiring diagram maker, create jenvoie en pieces jointes cv et lettre de motivation wiring diagram,
Residence Blanqui Villeurbanne Envoyer Lettre De Motivation Et Cv - All New Resume Examples & Resume Template
Residence Blanqui Villeurbanne Envoyer Lettre De Motivation Et Cv Wiring Diagram Online,residence blanqui villeurbanne envoyer lettre de motivation et cv wiring diagram basics, residence blanqui villeurbanne envoyer lettre de motivation et cv wiring diagram maker, create residence blanqui villeurbanne envoyer lettre de motivation et cv wiring diagram,
Appris Les Codes Du Cv Et Lettre De Motivation - All New Resume Examples & Resume Template
Appris Les Codes Du Cv Et Lettre De Motivation Wiring Diagram Online,appris les codes du cv et lettre de motivation wiring diagram basics, appris les codes du cv et lettre de motivation wiring diagram maker, create appris les codes du cv et lettre de motivation wiring diagram,
Format Lettre De Motivation Et Cv Canadien - All New Resume Examples & Resume Template
Format Lettre De Motivation Et Cv Canadien Wiring Diagram Online,format lettre de motivation et cv canadien wiring diagram basics, format lettre de motivation et cv canadien wiring diagram maker, create format lettre de motivation et cv canadien wiring diagram,
Piper betle extracts exhibit antitumor activity by augmenting antioxidant potential
Initially reported as a spontaneous murine mammary adenocarcinoma, the Ehrlich tumor can be grown in the majority of mouse strains and is accepted as a transplantable tumor model to examine the antitumor effects of a number of substances (20).. In the present study, a rapid increase in ascitic tumor volume was observed in EAC tumor-bearing mice and the treatment with Piper betle extracts reduced the intraperitoneal tumor burden, thereby reducing the tumor volume, tumor weight and viable tumor cell count, while increasing the life span of the tumor-bearing mice. Therefore, it may be hypothesized that the increase in lifespan of EAC-bearing mice in response to MPBL and EPBL at 100 mg/kg may be due to a decrease in nutritional fluid volume and a delay in cell division (12). Reductions in viable cell count and increased non-viable cell count towards normal in tumor hosts indicate antitumor effects against EAC cells in mice. These results indicate that MPBL and EPBL have a direct association with ...
Antitumor activity of methoxylated flavonoids separated from Achillea fragrantissima extract in Ehrlichs ascites carcinoma...
Introduction: Achillea fragrantissima extract has been used in folk medicine as an anticancer. The present study describes the antitumor activities of the extract and the flavonoid compounds and attempts to explain the mechanisms underlying these activities. Methods: The whole plant of A. fragrantissima was collected and ground to produce a fine powder which subjected to the maceration process. Step gradient elution was used using silica gel vacuum liquid chromatography (VLC). The fractions were compared by thin layer chromatography (TLC) and concentrated. Final purification was performed using Sephadex LH-20 to give three compounds cirsiliol, chrysosplenol D and cirsimaritin from F4 and one compound, eupatilin-7-methyl ether from F6. In this study, Ehrlichs ascites carcinoma (EAC) model was used as the model of cancer. Results: Achillea fragrantissima extract and its isolated methoxylated flavonoids significantly reduced the weight of tumor discs compared to EAC-control group. In addition,
NOPR: Acivicin with glutaminase regulates proliferation and invasion of human MCF-7 and OAW-42 cells-An <i style=>in vitro...
Tumor cells intensely utilize glutamine as the major source of respiratory fuel. Glutamine-analogue acivicin inhibits tumor growth and tumor-induced angiogenesis in Ehrlich ascites carcinoma. In the present study, antitumor properties of acivicin in combination with glutaminase enzyme is reported. Acivicin along with E. coli glutaminase synergistically reduced in vitro proliferation and matrigel invasion of human MCF-7 and OAW-42 cells. Effects of single and combined treatments with acivicin and glutaminase on angiogenic factors were also analyzed in these cell lines. Co-administration of the treatment agents inhibits the release of VEGF and MMP-9 by cells in culture supernatant significantly than single agent treatments. The result suggests that combination of acivicin with glutaminase may provide a better therapeutic option than either of them given separately for treating human breast and ovarian cancer. However, further studies are required to be conducted in vivo for its confirmation ...
Production And Characterization Of Biodiesel From Non-edible Sapodilla (chiku) Seed Oil | 4839
There are many medicinal applications found in Sapodilla fruit, bark, leaves & seeds like inhibition of ehrlich ascites carcinoma, in vitro and in vivo antioxi...
Apoptosis-inducing effects of morinda citrifolia and doxorubicin on the Ehrlich ascites tumour in balb-c mice. Conference...
Atıf İçin Kopyala Ulukaya E., AKGÜN DAR K. , ARMUTAK E. İ. , KAPUCU A. 15th Congress of the European-Cancer-Organization/34th Multidisciplinary Congress of the European-Society-for-Medical-Oncology, EJC SUPPLEMENTS, Berlin, Almanya, 20 - 24 Kasım 2009, cilt.7, no.2, ss.96 ...
Ecrire Une Lettre De Motivation Et Un Cv Grande Surfance - All New Resume Examples & Resume Template
Ecrire Une Lettre De Motivation Et Un Cv Grande Surfance Wiring Diagram Online,ecrire une lettre de motivation et un cv grande surfance wiring diagram basics, ecrire une lettre de motivation et un cv grande surfance wiring diagram maker, create ecrire une lettre de motivation et un cv grande surfance wiring diagram,
Aide Cv Et Lettre De Motivation Psychologue Du Travail - All New Resume Examples & Resume Template
Aide Cv Et Lettre De Motivation Psychologue Du Travail Wiring Diagram Online,aide cv et lettre de motivation psychologue du travail wiring diagram basics, aide cv et lettre de motivation psychologue du travail wiring diagram maker, create aide cv et lettre de motivation psychologue du travail wiring diagram,
The purpose of this study was to determine whether changes in long-chain free fatty acid concentration would alter the transport and utilization of another organic ligand that was bound to human plasma albumin. Ehrlich ascites cells were incubated in medium containing human albumin, and the uptake of 2-(4-hydroxyphenylazo)benzoic acid was measured relative to the free fatty acid concentration of the medium. As the molar ratio of free fatty acid to albumin was raised from 1 to 4, hydroxyphenylazobenzoic acid uptake by the cells increased. In contrast, cells loaded with large quantities of fatty acid took up no more hydroxyphenylazobenzoic acid from an albumin-free medium than did cells loaded with only small amounts of fatty acid. Equilibrium dialysis binding measurements indicated that the binding capacity of human albumin for hydroxyphenylazobenzoic acid decreased as the molar ratio of free fatty acid to albumin was raised. Therefore, it is likely that the free fatty acid-induced increase in ...
Peter Ehrlich | MCubed
ehrlich et al Maximum Hand-Rail And Hand-Rung Coupling Forces In Children: The Effects Of Diameter: Handhold diameter affects childrens ability to hang on. Human Factors (revisions submitted). Human Factors . 2012. In Press. Ehrlich et al 1. Clinico-pathologic Findings Predictive Of Relapse In Children With Stage III Favorable Histology Wilms Tumor: The Importance Of Lymph Nodes J Clinical Oncology Ehrlich et al Pediatric applied trauma research network: a call to action. J Trauma. 2010 Nov;69(5):1304-1307 Special commentary published simultaneously in Journal of Pediatric Surgery and Journal of Trauma. Ehrlich et al Evaluation of diagnostic performance of CT for detection of tumor thrombus in children with Wilms tumor: A report from the Childrens Oncology Group. Pediatr Blood Cancer. 2011 Jun 14. US Estimates of Hospitalized Children With Severe Traumatic Brain Injury: Implications for Clinical Trials. Pediatrics. 2011 Dec;129(1):e24-30. ...
The Population Bomb - Paul R. Ehrlich - Google Books
Paul Ehrlich, founder and first president of the Zero Population Growth organization, was born in Philadelphia, Pennsylvania. He received a B.A. in zoology from the University of Pennsylvania in 1953 and an M.A. and Ph.D. from the University of Kansas in 1955 and 1957, respectively. He became a member of the faculty at Stanford University in 1959 and was named Bing Professor of Population Studies in 1976. He is a recipient of a MacArthur Foundation fellowship, and in 1990 he was awarded Swedens Crafoord Prize, created by the Royal Swedish Academy of Sciences to honor researchers in those disciplines not covered by the Nobel Prize. An expert in population biology, ecology, evolution, and behavior, Ehrlich has published more than 600 articles and scientific papers. He is perhaps best known for his environmental classic The Population Bomb (1968). Paul Ehrlich and his wife Anne began working together shortly after their marriage in 1954. Anne Ehrlich received her B.S. in biology from the ...
Video | Dr. Dion Ehrlich, MD | Abington, PA | Ophthalmologist
Meet Doctor Dion R Ehrlich. Here are his vitals: Hes board certified, specializing in Ophthalmology with expertise in this area. Doctor Ehrlich is a highly experienced doctor, with 35 years of practice in the field Highly regarded by his patients they rate him 4 out of 4 stars. They point out the time he spends with them. He has won Patients Choice Award. Is affiliated with a highly rated hospital. Graduated from George Washington University. He completed his fellowship at The Ohio State University in 1978. His average waiting time is 11 minutes. He accepts new patients. He has a number of insurance plans accepted. Use Vitals.com to examine Doctor Dion R Ehrlich from Philadelphia, Pennsylvania. See patient comments make an appointment or even let us help you to prepare for your visit. Vitals .com where doctors are examined.. ...
Decreased macrophage‐mediated cytotoxicity in mammary‐tumor‐bearing mice is related to alteration of nitric‐oxide production...
TY - JOUR. T1 - Decreased macrophage‐mediated cytotoxicity in mammary‐tumor‐bearing mice is related to alteration of nitric‐oxide production and/or release. AU - Sotomayor, Eduardo M.. AU - Dinapoli, Michael R.. AU - Calderón, Cesar. AU - Colsky, Arthur. AU - Fu, Yang‐Xin ‐X. AU - Lopez, Diana M.. PY - 1995/3/3. Y1 - 1995/3/3. N2 - Peritoneal‐exudate macrophages (PEM) from mammarytumor‐bearing mice have impaired cytotoxic activity against syngeneic and allogeneic tumor targets. The ability of PEM from normal and tumor‐bearing mice to bind tumor targets was found to be similar in the presence or the absence of surrogate receptors, which enhanced the binding but not the killing of tumor targets by PEM from tumor‐bearing mice, suggesting that other mechanisms are involved in their impaired cytolytic activity. Soluble and membrane‐bound TNF‐α, as well as H2O2, were found in higher amounts in PEM from tumor bearers upon stimulation with LPS, as compared with PEM from normal ...
Dr. Nerkar Devidas Punjaji | PuneFoodHub.com
The challenge of virulent strains of salmonella.. Radiation induced detoxification of endotoxin (LPS) of Salmonella. Studied the macrophage activation by the detoxified LPS.. Prepared vaccine against ascites tumor cells by coupling the ascites cells(Sarcoma 180) to LPS and Con A through glutarladehyde. This vaccine offered 100% protection against the challenge of ascites tumor cells in mice.. Activation of macrophages by different microorganisms. Immobilisation of bacterial cells to hydrolyse proteins from trash fish.. Isolation and characterization of the marine bacteria for the production of omega three fatty acids and optimization of cultural conditions for production is being standardized. Bryonia plant extract was shown to have anticancer properties against MCS human mammary cancer cells in vitro, while there is no toxicity to normal cells. Established grape precooling and cold storage technology and developed packaging and palletization technology in India. Exported grapes in refer ...
Gr-1+ Myeloid Cells Derived from Tumor-Bearing Mice Inhibit Primary T Cell Activation Induced Through CD3/CD28 Costimulation |...
Previous observations in cancer patients and tumor-bearing animals suggested that myeloid lineage cells were involved in tumor-induced immunosuppression. Expansion of immature myeloid cells or macrophage/monocytes with characteristics of immune suppressive cells has been described in patients with head and neck cancer (6), gastric cancer (7), in mice bearing most carcinomas: Lewis lung carcinoma (8), Ehrlich carcinoma (9, 22), mammary adenocarcinoma (23), chemically induced fibrosarcoma (24), and colon carcinoma (13, 14, 15). This expansion was associated with a decline in T cell responses; however, little is known regarding the mechanism by which immune-suppressive cells inhibit primary T cell activation.. In the present study, we investigated how Gr-1+ myeloid cells, isolated from MCA-26 tumor-bearing mice and enriched by fractionation, contribute to inhibition of CD3/CD28-induced T cell activation. Several findings can be drawn from our experiments. We demonstrated a quantitative increase in ...
Anticancer Potential of Aqueous Ethanol Seed Extract of Ziziphus mauritiana against Cancer Cell Lines and Ehrlich Ascites...
Evidence-Based Complementary and Alternative Medicine (eCAM) is an international peer-reviewed, Open Access journal that seeks to understand the sources and to encourage rigorous research in this new, yet ancient world of complementary and alternative medicine.
Ehrlich reaction bilirubin chart.
central methylene group of bilirubin, first described by Dr. Ehrlich in [3, 4]. Serum bilirubin levels are frequently as high as 10 to 15 mg/dL and may be as . with Ehrlichs dimethylaminobenzaldehyde reagent to produce a pink colour, pigments react, therefore the concentration is termed total bilirubin (Table ...
Chère suisse - une plateforme pour rédiger une lettre à la Suisse future.
Chère Suisse est une initiative, qui invite les personnes ayant un lien avec la Suisse à écrire un lettre sur lavenir du pays.
Behavioral Approach to Weight Loss ( The Caryl Ehrlich Program Changes Liv...)
Health,...The Caryl Ehrlich Program Changes Lives with 10-Sessions for Permanent... ...NEW YORK March 10 /- Theres an alternative to dieting t... ...,Behavioral,Approach,to,Weight,Loss,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
Award positions Ehrlich among top string teachers in Illinois | Augustana College
No one was surprised, especially current and former students, when Dr. Janina Ehrlich received the 2020 Outstanding Studio Teacher award from the Illinois chapter of the American String Teachers Association.
Bernardoni F, Geisler D, King JA, Javadi AH, Ritschel F, Murr J, Reiter AMF, Rössner V, Smolka MN, Kiebel S, Ehrlich S. Altered Medial Frontal Feedback Learning Signals in Anorexia Nervosa. Biol Psychiatry. 2018 Feb; 83(3):235-243. doi: 10.1016/j.biopsych.2017.07.024. Bernardoni F, King JA, Geisler D, Birkenstock J, Tam FI, Weidner K, Roessner V, White T, Ehrlich S. Nutritional Status Affects Cortical Folding: Lessons Learned From Anorexia Nervosa. Biol Psychiatry. 2018 May; 84(9):692-701. doi: 10.1016/j.biopsych.2018.05.008.. Blokland GAM, Del Re EC, Mesholam-Gately RI, Jovicich J, Trampush JW, Keshavan MS, DeLisi LE, Walters JTR, Turner JA, Malhotra AK, Lencz T, Shenton ME, Voineskos AN, Rujescu D, Giegling I, Kahn RS, Roffman JL, Holt DJ, Ehrlich S, Kikinis Z, Dazzan P, Murray RM, Di Forti M, Lee J, Sim K, Lam M, Wolthusen RPF, de Zwarte SMC, Walton E, Cosgrove D, Kelly S, Maleki N, Osiecki L, [...]. The Genetics of Endophenotypes of Neurofunction to Understand Schizophrenia (GENUS) ...
18+ lettre de motivation moderne | karinyathaicuisine
What kind of accounting is essential. Management accounting is made for internal clients like management and employees to help in the day to day functioning of the corporation. It may appear to be a complicated endeavor to many and not having applicable types could be one reason behind it. If you prepared the trust bookkeeping all on your own or together with the support of a lawyer, possess the trust accounting form assessed by means of a CPA before sending it to the beneficiaries. Accounting is a broad term that is utilized to define the monitoring and evaluation of a particular function, in order to maintain certain set of criteria for a company or business. Should you hunt for bookkeeping on the internet you may think of endless publications, articles, terms, and definitions. Though a probate accounting in California doesnt demand the preparation of some particular types or using any specific format, there are numerous pieces of advice you must put on your account. The accountants have some ...
Affice Avant la Lettre | Albright-Knox
serigraph. Edition: 40/75. support: 15 3/4 x 14 9/16 inches (40 x 36.99 cm). Collection Albright-Knox Art Gallery, Buffalo, New York. Charles W. Goodyear Fund, 1963. P1963:1. ...
Barbara E Ehrlich, PhD > Liver Center | Yale School of...
When you express interest in a specific study, the information from your profile will be sent to the doctor conducting that study. If youre eligible to participate, you may be contacted by a nurse or study coordinator. If you select a health category rather than a specific study, doctors who have active studies in that area may contact you to ask if you would like to participate. In both cases, you will be contacted by the preferred method (email or phone) that you specified in your profile. ...
environment | Public Radio International
Living on Earth November 02, 2007 If you ask Paul Ehrlich, a professor of population studies at Stanford University, hell tell you the new UN report on the state of the global environment is old news. Dr. Ehrlich talks with host Bruce Gellerman about overpopulation, famine, and climate change, and the urgent need for the human species to save itself from disasters of its own making. ...
Candlewood Suites Raleigh Crabtree - Room Pictures & Amenities
Candlewood Suites Raleigh Crabtree room photos and amenities. Candlewood Suites Raleigh Crabtree rooms include free Internet, a full kitchen, and a large workspace.
Michael Crabtree suffers torn Achilles in workout - ProFootballTalk
The 49ers suffered a major blow during OTAs, as wide receiver Michael Crabtree suffered what could be a season-ending injury. According to Mike Garafolo of USA Today, Crabtree tore his Achilles during a workout Tuesday, and will need surgery to repair the injury.
CRABTREE, ERIC (Texas Accountancy)
CRABTREE, ERIC is a Accountancy licensed to practice in Texas. The address on file for CRABTREE, ERIC is 21127 BEECH LANDING LN KATY TX 77450. This accountants license is current. The license was granted 03/01/1998 and expired on 08/31/2017.
Hadopi : le million davertissements et une car...
Dans la troisième lettre dinformation depuis son inauguration en 2010, la Hadopi (Haute Autorité pour la Diffusion des Oeuvres et de la Protection des droits sur Internet)... | Geomatic
pure-sante.info at WI. PureSanté - Des idées claires sur la santé naturelle
pure-sante.info at WI. PureSanté est la lettre dinformation gratuite et indépendante qui publie en temps réel les découvertes de la médecine naturelle validées par la recherche scientifique
Attention Mir Bochurim | Matzav.com
Your statement applies as much for non corona times…this whole Seminary mishigas…which we didnt have years ago…time to reign it in. The cost is a lot more than financial….and as a shadchan for many years…its time to stop evaluating people by their Seminary experiences…or particular school, instead of on the character of the individual. We have gone bonkers about the whole experience as if its a given that without going…you are doomed shidduch wise. We all got married WITHOUT SEMINARY and raised wonderful ehrlich families without the expenses to our parents, financially and emotionally. Your chinuch comes from your home and 12 years of schooling should suffice to grow into a healthy ehrlicha kid with healthy haskofos…of course…growth is continuous…but PLEASE PLEASE stop judging girls and boys by which school, seminary or yeshiva they attend. You can grow to be a gadol b torah on a bench in beis medresh if you have hasmuda… not to say you should be doing that…but ...
Items where Author is Lubeck, M. - ePIC
Ehrlich, H. , Deutzmann, R. , Capellini, E. , Koon, H. , Solazzo, C. , Yang, Y. , Ashford, D. , Thomas-Oates, J. , Lubeck, M. , Baessmann, C. , Langrock, T. , Hoffmann, R. , Wörheide, G. , Reitner, J. , Simon, P. , Ereskovsky, A. V. , Mertig, M. , Vyalikh, D. V. , Molodtsov, S. L. , Worch, H. , Brunner, E. , Smetacek, V. and Collins, M. (2010 ...
Items where Author is Capellini, E. - ePIC
Ehrlich, H. , Deutzmann, R. , Capellini, E. , Koon, H. , Solazzo, C. , Yang, Y. , Ashford, D. , Thomas-Oates, J. , Lubeck, M. , Baessmann, C. , Langrock, T. , Hoffmann, R. , Wörheide, G. , Reitner, J. , Simon, P. , Ereskovsky, A. V. , Mertig, M. , Vyalikh, D. V. , Molodtsov, S. L. , Worch, H. , Brunner, E. , Smetacek, V. and Collins, M. (2010 ...
Search Results | Academic Commons
Sanchez, Pedro A.; Palm, Cheryl A.; Sachs, Jeffrey D.; Denning, Glenn L.; Flor, David Rafael; Harawa, Rebbie; Jama, Bashir; Kiflemariam, Tsegazeab; Konecky, Bronwen; Kozar, Raffaela; Lelerai, Eliud; Malik, Alia; Mutuo, Patrick; Niang, Amadou; Okoth, Herine; Place, Frank; Sachs, Sonia Ehrlich; Said, Amir; Siriri, David; Teklehaimanot, Awash; Wang, Karen; Wangila, Justine; Zamba, ...
PressReader - Cecil Whig: 2016-09-14 - Trumps Dun-dalk visit un-der-scores chang-ing elec-torate
Spe-cial from the Dun-dalk Ea-gle. - Repub-li-can pres-i-den-tial nom-i-nee Don-ald Trump vis-ited the Boule-vard Diner as a part of his visit to Bal-ti-more on Mon-day af-ter-noon.. Around 100 sup-port-ers, as well as lo-cal politi-cians, came out to the diner to show sup-port for the nom-i-nee, who had spo-ken at the Na-tional Guard As-so-ci-a-tion of the United States 138th Gen-eral Con-fer-ence & Ex-hi-bi-tion in the Bal-ti-more Con-ven-tion Cen-ter ear-lier in the day.. Trump had lunch with sev-eral po-lit-i-cal fig-ures, in-clud-ing State Sen. Johnny Ray Salling (R-Bal-ti-more County), for-mer Mary-land Gov. Robert Ehrlich and for-mer New York City Mayor Rudy Gi-u-liani.. It was just great see-ing him, Salling said. I had lunch with Don-ald Trump. We talked about the is-sues in our state and some of the is-sues in our coun-try. We. DUN-DALK. had a good time.. Bal-ti-more County Coun-cil-man Todd Cran-dell, who rep-re-sents Es-sex and Dun-dalk, said it means a lot to th-ese ...
Crabtree & Evelyn Body Anti-Ageing Products | eBay
Shop from the world's largest selection and best deals for Crabtree & Evelyn Body Anti-Ageing Products. Shop with confidence on eBay!
Ectopic expression of miR-31 suppresses migration and i | Open-i
Ectopic expression of miR-31 suppresses migration and invasion of ESCC and EAC cell lines. TE8 and FLO1 cells were transfected with pre-miR-31 containing vector
Ehrlich ascites carcinoma
Ehrlich-Lettre ascites carcinoma (EAC) is also known as Ehrlich cell. It was originally established as an ascites tumor in mice ... The tumor was cultured in vivo, which became known as the Ehrlich cell. After 1948 Ehrlich cultures spread around research ... Dupre, Ann M.; Hempling, H. G. (December 1978). "Osmotic properties of ehrlich ascites tumor cells during the cell cycle". ... ". "Ehrlich Cells (Molecular Biology)". DuPre, AM; Hempling, HG (1978). "Osmotic properties of ehrlich ascites tumor cells ...
"Sacharose density gradient separation of Ehrlich ascites carcinoma and L-5178Y tumor cells in different cell cycle phases". ... Interference of Bruneomycin with the Cell Cycle of Ehrlich's Ascites Carcinoma]. Biológia (in Slovak). 35 (12): 875-80. ... Horáková, K (1975). "Ribonucleases in mouse ascitic tumor cells during ageing in vivo and in vitro". Advances in Experimental ... Horáková, K (1972). "Polynucleotidases in mouse ascitic tumour cells". Neoplasma. 19 (5): 459-68. PMID 4345214. Fuska, JAN; ...
This property might be due to an acidic polypeptide found in its leaves that inhibited growth of Ehrlich ascites carcinoma ... In folk medicine, it is used to combat tumors. ...
Mady, E. A. (2002). "Antitumor and biochemical effects of Echis coloratus crude venom on Ehrlich ascites carcinoma cells in ... "Role of dietary magnesium and/or manganese variables on ehrlich ascites tumor‐bearing mice". Nutrition and Cancer. 12 (3): 279- ... "Antitumor Activities of Iodoacetate and Dimethylsulphoxide Against Solid Ehrlich Carcinoma Growth in Mice". Biological Research ...
Ehrlich carcinoma and Crocker sarcoma of mice and the Walker carcinoma of rats. He was aware that precision drugs would be ... even if the tumor cannot be completely eliminated. We will be satisfied if we ca slow down it growth, in order to preserve the ... Later, Ehrlich and his students found that some azo dyes were effective against African sleeping sickness. In 1913, P. ... For example, German biologist Paul Ehrlich used methylene blue, a type of azo dye, to kill malarial parasites in experimental ...
"Antitumor Activities of Iodoacetate and Dimethylsulphoxide Against Solid Ehrlich Carcinoma Growth in Mice". Biological Research ... Apffel, C. A.; Arnason, B. G.; Peters, J. H. (1966). "Induction of tumour immunity with tumour cells treated with iodoacetate ... Several studies have shown iodoacetate has anti-tumor effects. In 2002 Dr. Fawzia Fahim showed that "a single IAA treatment of ... In 1966 Charles A. Apffel, Barry G. Arnason & John H. Peters showed anti-tumor activity for iodoacetate. Iodide is a naturally ...
Patrick S. Moore
"Human transcriptome subtraction by using short sequence tags to search for tumor viruses in conjunctival carcinoma". Journal of ... the 2017 Paul Ehrlich and Ludwig Darmstaedter Prize and the 2017 Passano Award. They are 2017 Clarivate Citation Laureates. " ... In 1994, they discovered a new human herpesvirus, KSHV, in a KS tumor and along with several collaborators showed that it was ... His laboratory currently seeks to understand the role of tumor virus immunoevasion of the innate immune system as a cause for ...
Sp1 transcription factor
"Withaferin A suppresses the expression of vascular endothelial growth factor in Ehrlich ascites tumor cells via Sp1 ... September 2003). "Che-1 arrests human colon carcinoma cell proliferation by displacing HDAC1 from the p21WAF1/CIP1 promoter". ...
Stuart A. Aaronson
His discovery of erbB2 as a v-erbB-related gene amplified in a human breast carcinoma and the demonstration of its transforming ... Current research includes investigations into the mechanisms by which tumor suppressor genes induce permanent growth arrest/ ... 1982 Rhoads Memorial Award 1982 PHS Meritorious Service Medal 1989 Paul Ehrlich Award 1989 PHS Distinguished Service Medal 1990 ... "Wnt pathway aberrations including autocrine Wnt activation occur at high frequency in human non-small-cell lung carcinoma". ...
These effects seem to be largely mediated by mutations at guanine in codon 249 of the p53 gene, a tumor suppressing gene, and ... Prevalence of hepatocellular carcinoma in individuals exposed to aflatoxin, increases with co-infection of hepatitis B virus. ... Yu J, Chang PK, Ehrlich KC, et al. (March 2004). "Clustered pathway genes in aflatoxin biosynthesis". Appl. Environ. Microbiol ... Up to 44% of hepatocellular carcinomas in regions with high aflatoxin exposure bear a GC → TA transversion at codon 249 of p53 ...
Since the late 1970s, Rammensee has been focusing on immunology with the specific aim of using tumor immunology to fight ... 2013 Paul Ehrlich and Ludwig Darmstaedter Prize, 1996 Robert Koch Prize, 1993 Gottfried Wilhelm Leibniz Prize, 1992 Heinz Maier ... The immunopeptidomic landscape of ovarian carcinomas. Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):E9942-E9951. doi: 10.1073/ ... Rammensee has contributed essentially to the research fields of MHC biology and tumor immunology and to the development of ...
List of MeSH codes (C04)
... carcinoma, ehrlich tumor MeSH C04.557.470.200.220 - carcinoma, giant cell MeSH C04.557.470.200.240 - carcinoma in situ MeSH ... carcinoma, signet ring cell MeSH C04.557.470.200.025.415.410 - krukenberg tumor MeSH C04.557.470.200.025.420 - carcinoma, skin ... sertoli-leydig cell tumor MeSH C04.557.475.750.847.249 - leydig cell tumor MeSH C04.557.475.750.847.500 - sertoli cell tumor ... carcinoma, large cell MeSH C04.557.470.200.280 - carcinoma, lewis lung MeSH C04.557.470.200.300 - carcinoma, non-small-cell ...
... but is significantly focally deleted across the entire dataset of 3131 tumors, suggesting that IRF8 is potentially a tumor ... Sharf R, Azriel A, Lejbkowicz F, Winograd SS, Ehrlich R, Levi BZ (June 1995). "Functional domain analysis of interferon ... Molecular analysis indicated that the IRF8 gene promoter is hypermethylated in human colon carcinoma cells, suggesting that ... Sharf R, Azriel A, Lejbkowicz F, Winograd SS, Ehrlich R, Levi BZ (1995). "Functional domain analysis of interferon consensus ...
"Characterization of the cell-cycle-regulated protein calcyclin from Ehrlich ascites tumor cells. Identification of two binding ... S100A6 to be reported as possible diagnostic marker of papillary thyroid carcinoma. GRCh38: Ensembl release 89: ENSG00000197956 ... "Proteomic study of thyroid tumors reveals frequent up-regulation of the Ca2+ -binding protein S100A6 in papillary thyroid ... carcinoma". Thyroid. 20 (10): 1067-76. doi:10.1089/thy.2009.0400. PMID 20629554. Schäfer BW, Heizmann CW (1996). "The S100 ...
MSI-L tumors result from less than 30% of unstable MSI biomarkers. MSI-L tumors are classified as tumors of alternative ... MSI has been evident in the cause of sebaceous carcinomas. Sebaceous carcinomas are a subset of a larger pathology, Muir-Torre ... Ehrlich M, ed. (2000). DNA alterations in cancer: genetic and epigenetic changes. Natick, MA: Eaton Publ. p. 178. ISBN 978-1- ... MSI tumors in 15% of sporadic colorectal cancer result from the hypermethylation of the MLH 1 gene promoter, whereas MSI tumors ...
... the two decided to look at fine structures within the cells of the Ehrlich ascites carcinoma, a commonly used model for cancer ... "The Coming of Age of Tumor Virology." Cancer Research 37 (1977): 1255-1263 "Hemoglobin Synthesis in Murine Virus-induced ...
Harald zur Hausen
"Prize Winners of the Paul Ehrlich and Ludwig Darmstaedter Prize" (PDF). uni-frankfurt.de. The Paul Ehrlich Foundation. ... This discovery paid off several years later, in 1983, when zur Hausen identified HPV 16 DNA in cervical cancer tumors by means ... M Dürst; L Gissmann; H Ikenberg; H zur Hausen (1 June 1983). "A papillomavirus DNA from a cervical carcinoma and its prevalence ... Paul Ehrlich and Ludwig Darmstaedter Prize (1994) International member of the American Philosophical Society (1998) Virchow ...
Fibroblast growth factor 8
... the ability for FGF8 to regulate cell proliferation has caused interest in its effects on tumors or squamous cell carcinoma. ... Gemel J, Gorry M, Ehrlich GD, MacArthur CA (July 1996). "Structure and sequence of human FGF8". Genomics. 35 (1): 253-7. doi: ... Overexpression of this gene has been shown to increase tumor growth and angiogenesis. The adult expression of this gene was ... This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. ...
Hepatitis C virus core variants isolated from liver tumor but not from adjacent non tumor interact with Smad3 and inhibit the ... doi: 10.1002/hep.24087 Arumugam M, Raes J, Brechot C, Merieux A, Weissenbach J, Ehrlich SD, Bork P. Enterotypes of the human ... hepatocellular carcinoma, HCC), as well as the molecular mechanisms underpinning liver regeneration and cancer (especially the ... Hepatocellular carcinoma is associated with an increased risk of hepatitis B virus recurrence after liver transplantation. ...
"Renal cell carcinoma antigen is expressed by yolk sac tumors and yolk sac elements of embryonal carcinomas". Applied ... Grunau C, Sanchez C, Ehrlich M, van der Bruggen P, Hindermann W, Rodriguez C, Krieger S, Dubeau L, Fiala E, De Sario A (May ... Götte K, Usener D, Riedel F, Hörmann K, Schadendorf D, Eichmüller S (July 2002). "Tumor-associated antigens as possible targets ... "Entrez Gene: RAGE renal tumor antigen". Eichmüller S, Usener D, Jochim A, Schadendorf D (August 2002). "mRNA expression of ...
It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants ... Germani A, Prabel A, Mourah S, Podgorniak MP, Di Carlo A, Ehrlich R, Gisselbrecht S, Varin-Blank N, Calvo F, Bruzzoni- ... in breast carcinomas". Int. J. Cancer. 107 (1): 155-8. doi:10.1002/ijc.11343. PMID 12925972. S2CID 20908722. Dick FA, Sailhamer ... "The LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activity". J. ...
Jun dimerization protein
... of AP-1 repressor JDP2 is associated with tumor metastasis and poor prognosis in patients with pancreatic carcinoma". The ... Ji H, Ehrlich LI, Seita J, Murakami P, Doi A, Lindau P, et al. (September 2010). "Comprehensive methylome map of lineage ... JDP2 shows the gene amplification of head and neck squamous-cell carcinoma. In pancreatic carcinoma, downregulation of JDP2 is ... July 2005). "Tumor model-specific proviral insertional mutagenesis of the Fos/Jdp2/Batf locus". Virology. 337 (2): 353-364. doi ...
It is now believed that the Kaiser had hybrid verrucous carcinoma, a very rare form of verrucous carcinoma, and that Virchow ... Experiments also show that drugs that block inflammation simultaneously inhibit tumour formation and development. Virchow was ... and that of Paul Ehrlich, who studied at the Charité while Virchow was developing microscopic pathology there. One of Virchow's ... Metastasis was first described by Karl Thiersch in the 1860s.) He made a crucial observation that certain cancers (carcinoma in ...
"Prize Winners of the Paul Ehrlich and Ludwig Darmstaedter Prize" (PDF). The Paul Ehrlich Foundation. Retrieved 17 October 2022 ... The first analyzed tumors included those of the colon, breast, pancreas, and brain. These studies outlined the landscapes of ... April 1989). "Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas". Science. 244 (4901): 217-21. Bibcode: ... The Paul Ehrlich and Ludwig Darmstaedter Prize from the Paul Ehrlich Foundation 1998 - The William Allan Award from the ...
... the Brown-Pearce Carcinoma. They studied transmission of the tumor by inoculating a series of more than twenty other rabbits, ... Building on the work of Paul Ehrlich in Germany, who had developed an arsenic-derived drug called Salvarsan for the treatment ... While the fundamental nature of the tumor remained the same, its malignancy varied. They attempted to understand the ... Because it was thoroughly studied, and replicable, the Brown-Pearce tumor became a standard test material in cancer ...
In ovarian cancer, p27 negative tumors progressed in 23 months compared to 85 months in p27 positive tumors and thus could be ... In hepatocellular carcinoma cells p27 co-localizes with actin fibers to act on GTPase Rac and induce cell migration. In breast ... Liu X, Sun Y, Ehrlich M, Lu T, Kloog Y, Weinberg RA, Lodish HF, Henis YI (November 2000). "Disruption of TGF-beta growth ... In most cancers reduced levels of nuclear p27 are correlated with increased tumor size, increased tumor grade, and a higher ...
... (September 11, 1904 - July 19, 1999) was a Polish-American virologist who discovered two different tumor viruses- ... Principal 1978 Paul Ehrlich-Ludwig Darmstaeder Prize in Frankfurt Griffuel Prize in Paris (1978) Elected to the National ... murine polyomavirus is closely related to the human Merkel cell polyomavirus that causes most forms of Merkel cell carcinoma. ...
Uridine monophosphate synthase
... monophosphate from orotate in Ehrlich ascites carcinoma. Purification by tandem affinity chromatography of uridine-5'- ... "Orotate phosphoribosyltransferase expression level in tumors is a potential determinant of the efficacy of 5-fluorouracil". ... "Effect of 5-phosphoribosyl-a-pyrophosphate on de novo pyrimidine biosynthesis in cultured Ehrlich ascites cells made permeable ... phosphate decarboxylase enzyme complex from mouse Ehrlich ascites cells". The Journal of Biological Chemistry. 254 (4): 1143-50 ...
Another tumor-lysing virus that specifically targets tumor cells with an activated Ras pathway is a type II herpes simplex ... Rotblat B, Ehrlich M, Haklai R, Kloog Y (2008). "The Ras inhibitor farnesylthiosalicylic acid (Salirasib) disrupts the ... Parada LF, Tabin CJ, Shih C, Weinberg RA (June 1982). "Human EJ bladder carcinoma oncogene is homologue of Harvey sarcoma virus ... The tumour suppressor gene NF1 encodes a Ras-GAP - its mutation in neurofibromatosis will mean that Ras is less likely to be ...
Ehrlich, HP; Diez, T (2003). "Role for gap junctional intercellular communications in wound repair". Wound Repair Regen. 11 (6 ... Prutkin L (February 1975). "Mucous metaplasia and gap junctions in the vitamin A acid-treated skin tumor, keratoacanthoma". ... "Gap junction blockage interferes with neuronal and astroglial differentiation of mouse P19 embryonal carcinoma cells". Dev. ... May 1996). "Protein and messenger RNA expression of connexin43 in astrocytomas: implications in brain tumor gene therapy". J. ...
Tumor-suppressor through Tumor metastasis-inhibiting peptide KISS1 Another study, led by Zhang B, created a L. lactis strain ... Bolotin A, Quinquis B, Renault P, Sorokin A, Ehrlich SD, Kulakauskas S, Lapidus A, et al. (2004). "Complete sequence and ... Lactococcus lactis NZ9000 secretes a bioactive kisspeptin that inhibits proliferation and migration of human colon carcinoma HT ... In addition, it was demonstrated that tumor growth can be inhibited by the LAB strain itself due to the LAB's ability to ...
Blood vessels in tumors are very different from those seen in normal tissues. As a tumor grows, tumor cells furthest away from ... The term was coined in the early 1900s by Paul Ehrlich as meaning any use of chemicals to treat any disease (chemo- + -therapy ... such as one in which a female pharmacist was diagnosed with papillary transitional cell carcinoma. Twelve years before the ... The newly formed tumor vasculature is poorly formed and does not deliver an adequate blood supply to all areas of the tumor. ...
"Definition of tumor-associated antigens in hepatocellular carcinoma". Cancer Epidemiology. 9 (3): 285-290. ISSN 1055-9965. PMID ... Paul Ehrlich and Ludwig Darmstaedter Prize "Ehrendoktorwürde für Özlem Türeci und Uğur Şahin". Philipps-Universität Marburg (in ... This technology relies on targeting tumor-specific mutations that are not present in normal cells. Each patient's tumor has a ... They discovered tumor antigens relevant for treatment of various types of cancers, e.g. stomach cancer, pancreatic cancer, ...
Robert L. Ehrlich, Jr. (Extension of Remarks - June 4, 1997)", Congressional Record 105th Congress (1997-1998), The Library of ... "Henrietta's Tumor", RadioLab segment featuring Deborah Lacks and audio of Skloot's interviews with her, and original recordings ... "Squamous Cell Carcinoma". Skin Cancer Foundation. Retrieved December 31, 2016. Skloot 2010, p. 27. World Cancer Report 2014. ... Adenocarcinomas are a type of cancerous tumor or an abnormal growth of epithelial tissue. 10% to 15% of cancers of the cervix ...
... pancreatic tumors, colorectal tumors, and ovarian tumors. FAM149A has two transcription variants, transcript variant 1 and ... Xu X, Tsumagari K, Sowden J, Tawil R, Boyle AP, Song L, Furey TS, Crawford GE, Ehrlich M (December 2009). "DNaseI ... "Gene expression changes in initiation and progression of oral squamous cell carcinomas revealed by laser microdissection and ... From the information in the second table, common complications involving FAM149A expression include adrenal tumors, ...
Peter M. Howley
From 1984 to 1993 he was Chief of the NIC's Laboratory of Tumor Virus Biology. In 1993 he became a professor of pathology at ... Paul Ehrlich and Ludwig Darmstaedter Prize (also awarded to Harald zur Hausen) 1996 - Fellow of the American Academy of Arts & ... "The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines". Proceedings of the National Academy of ... simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between ...
Peretz J, Vrooman L, Ricke WA, Hunt PA, Ehrlich S, Hauser R, et al. (August 2014). "Bisphenol a and reproductive health: update ... Bisphenol A exposure in fetal female rats leads to mammary gland morphogenesis, increased formation of ovarian tumors, and ... exposed to diethylstilbestrol in utero during the first trimester have are more likely to develop clear cell vaginal carcinoma ...
Although c-Raf is very clearly capable of mutating into an oncogene in experimental settings, and even in a few human tumors, ... Germani A, Prabel A, Mourah S, Podgorniak MP, Di Carlo A, Ehrlich R, Gisselbrecht S, Varin-Blank N, Calvo F, Bruzzoni- ... such as renal cell carcinoma and melanoma. Several other molecules followed up, such as Vemurafenib, Regorafenib, Dabrafenib, ... The latter became the focus of research in recent years, since a large portion of human tumors carry oncogenic 'driver' ...
Direct biopsy of tumors of the liver may aid the diagnosis, although this may be avoided if the source is clear (e.g. spread ... The first liver aspirate was performed by the German physician Paul Ehrlich in 1883. In 1923, the first report of percutaneous ... Multiphasic MRI is useful in diagnosing various types of liver lesions such as hepatocellular carcinoma, cholangiocarcinoma, ...
Ehrlich, Brian D. Harfe, Steven A. Vokes. Dynamics of BMP signaling in limb bud mesenchyme and polydactyly (2014) Developmental ... and sarcoma carcinomas. More specifically, the Grem1 binding site (between residues 1 to 67) interacts with the binding protein ... "Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor ...
It can also serve as a marker of basal cell carcinoma, transitional cell carcinoma, salivary gland tumors, and thymoma. The ... Ehrlich P, Sybert VP, Spencer A, Stephens K (May 1995). "A common keratin 5 gene mutation in epidermolysis bullosa simplex-- ... Studies on lung cancer have also shown that squamous cell carcinomas give rise to tumors with elevated K5 levels, and that they ... This process has a large role in tumor progression and metastasis since it helps enable tumor cells to travel throughout the ...
IMSEAR at SEARO: Evaluation of anti-tumor efficacy of injectable Centchroman in mice bearing Ehrlich ascites carcinoma.
Evaluation of anti-tumor efficacy of injectable Centchroman in mice bearing Ehrlich ascites carcinoma. Indian Journal of ... Evaluation of anti-tumor efficacy of injectable Centchroman in mice bearing Ehrlich ascites carcinoma. ... enhanced anti-tumor efficacy against Ehrlich ascites carcinoma. ... Anti-tumor efficacy of Centchroman formulated as niosomes and ... gel implant was evaluated in Swiss albino mice bearing Ehrlich ascites carcinoma at 10 mg/kg body weight dose given ...
Ehrlich carcinoma | GreenMedInfo | Disease | Natural Medicine
Tumors,Iodine,Lectin-Induced Cancer,Vegetables: All,Thyroid Cancer,Fruit: All,Fruit: All ... Diseases : Ehrlich carcinoma. Pharmacological Actions : Antioxidants, Apoptotic, Superoxide Dismutase Up-regulation, Tumor ... Potential anti-tumor activity of kefir-induced juglone and resveratrol fractions against ehrlich ascites carcinoma.Dec 31, 2019 ... Diseases : Breast Cancer, Ehrlich carcinoma. Pharmacological Actions : Antiproliferative , Apoptotic, Tumor Suppressor Protein ...
Merkel Cell Carcinoma and Rare Appendageal Tumors: Overview, Tumors of the Epidermis, Tumorlike Lesions of Fibrous or Elastic...
Cutaneous tumors encompass a vast array of malignancies, from neuroendocrine to lymphoid. In addition to primary malignancies, ... Moyer KE, Banducci DR, Graham WP 3rd, Ehrlich HP. Dupuytrens disease: physiologic changes in nodule and cord fibroblasts ... encoded search term (Merkel Cell Carcinoma and Rare Appendageal Tumors) and Merkel Cell Carcinoma and Rare Appendageal Tumors ... clear cell carcinoma, and mucinous carcinoma.  All these tumors have the capacity to metastasize to skin and regional ...
FURTHER EVIDENCE FAVORING THE CONCEPT OF THE STEM CELL IN ASCITES TUMORS OF RATS | Semantic Scholar
... of tumor cells as primary contributors to the growth of the tumor. T t has been shown that in each of the tumors studied, ... eliavior of the tumor, i t is the stem (.ells which determine the genetic behavior of a tumor. Further data to tic presented in ... of tumor cells as primary contributors to the growth of the tumor and of differences in the genetic constitution of thcsc stem ... Cytological investigations based on morphological and statisticzl analysis of the chromosomes in several ascites tumors of rats ...
Oxythiamine and dehydroepiandrosterone inhibit the nonoxidative synthesis of ribose and tumor cell proliferation
... reactions in the tumor proliferation process by characterizing tumor growth patterns and synthesis of the RNA ribose moiet … ... Carcinoma / pathology * Carcinoma, Ehrlich Tumor / metabolism* * Cell Division / drug effects * Dehydroepiandrosterone Sulfate ... In vivo testing of 400 mg/kg OT or dehydroepiandrosterone-sulfate in C57BL/6 mice hosting Ehrlichs ascitic tumor cells ... reactions in the tumor proliferation process by characterizing tumor growth patterns and synthesis of the RNA ribose moiety in ...
RGD Reference Report - Immune modulation and apoptosis induction: Two sides of antitumoural activity of a standardised herbal...
Ehrlich tumor carcinoma treatment. ISO. RGD:708418. 11352683; 11352683. RGD. Ehrlich tumor carcinoma treatment. IDA. 11352683; ... WSF at 150mg/kg, i.p., inhibited >50% tumour growth in the mouse tumour models. In tumour-bearing mice, WSF inhibited the ... Ehrlich tumor carcinoma treatment. ISO. RGD:619830. 11352683; 11352683. RGD. ... Deregulated apoptosis and suppressed tumour reactive immunity render tumour cells to grow amok in the host body. Traditionally ...
An experimental study on the lymphatic dissemination of the solid Ehrlich tvjnor in mice | Brazilian Journal of...
Lymphatic metastasis, Carcinoma (Ehrlich tumor), Lymph nodes, Mast cells, Mouse Abstract. Metastasis to regional lymph nodes is ... The aim of the present study was to characterize the Ehrlich tumor as a model of lymphatic metastasis in mice. Animals were ... The migration of tumor cells was detected by a biological assay as early as 1 hour post-inoculation. The solid tumor growth in ... Ehrlich tumor was considered as a suitable model for the study of lymphatic metastasis. ...
DNA Content of Nuclei and Chromosome Number in Sublines of the Ehrlich Ascites Carcinoma* | Cancer Research | American...
These findings are discussed in regard to the experimental use of ascites tumor populations. ... DNA Content of Nuclei and Chromosome Number in Sublines of the Ehrlich Ascites Carcinoma* Jerome J. Freed; Jerome J. Freed ... Jerome J. Freed, David A. Hungerford; DNA Content of Nuclei and Chromosome Number in Sublines of the Ehrlich Ascites Carcinoma* ... The distribution of nuclear DNA values in the Lettré-Ehrlich mouse ascites carcinoma, and in some of its hypertetraploid (EL88 ...
Anticancer potential of Michelia champaca Linn. bark against Ehrlich ascites carcinoma (EAC) cells in Swiss albino mice
Furthermore, it was found that bark extract decreased tumor cell proliferation (77.46%; P,0.01), tumor weight (42.13%; P,0.001 ... stem-bark of Mycelia champaca is subjected to evaluate its anti-proliferative effect against Ehrlich ascites carcinoma (EAC) ... stem-bark of Mycelia champaca is subjected to evaluate its anti-proliferative effect against Ehrlich ascites carcinoma (EAC) ... tumor weight measurement, and survival time etc. The mechanism of EAC killing was examined by observation of cell morphology ...
TPEN - ALX-450-011 - Enzo Life Sciences
Find Research outputs - Manipal Academy of Higher Education, Manipal, India
Ashwagandha: MedlinePlus suplementos
Antitumor and radiosensitizing effects of withaferin A on mouse Ehrlich ascites carcinoma in vivo. Acta Oncol. 1996;35:95-100. ... on a transplantable mouse tumor, Sarcoma-180. Indian J Exp Biol. 1993;31:607-611. View abstract. ... In vivo growth inhibitory and radiosensitizing effects of withaferin A on mouse Ehrlich ascites carcinoma. Cancer Lett. 8-16- ... on a transplantable mouse tumor, Sarcoma 180. Indian J Exp Biol. 1992;30:169-172. View abstract. ...
Subject: antineoplastic agents / Subject term: antineoplastic activity / Text Availability: Citation in PubAg - PubAg Search...
... in combination with low level ionising radiation in female mice with solid tumors from inoculated Ehrlich ascites carcinoma ... 3. Anticancer Effects of Combination of Indole-3-Carbinol and Hydroxychloroquine on Ehrlich Ascites Carcinoma via Targeting ... This study aimed to assess I3C antineoplastic activity alone and with hydroxychloroquine (HCQ) on Ehrlich ascites carcinoma ( ... Tumor cell-inoculated mice received daily extract doses (100 mg/kg, 200 mg/kgBW) with or without a sing .... DOI:. 10.1080/ ...
Carcinoma, Ehrlich Tumor Entry term(s). Ascites Tumor, Ehrlich Ehrlich Ascites Tumor Ehrlich Tumor Carcinoma Tumor, Ehrlich ... Ascites Tumor, Ehrlich. Ehrlich Ascites Tumor. Ehrlich Tumor Carcinoma. Tumor, Ehrlich Ascites. ... tumor ascítico de Ehrlich tumor carcinoide de Ehrlich tumor de Ehrlich Scope note:. Tumor trasplantable, maligno, pobremente ... Carcinoma, Ehrlich Tumor - Preferred Concept UI. M0003437. Scope note. A transplantable, poorly differentiated malignant tumor ...
IMSEAR at SEARO: Search
Ehrlich ascites carcinoma cells*. Authors: Biswakanth Kar, Pallab K Haldar, Goutam Rath, Goutam Ghosh. Pages: 98 - 103. ... Traditionally, the various parts of the plants have been used in the treatment of wound healing, pain, and tumor. Objective: To ... and bcl2 gene expression in Ehrlich ascites carcinoma (EAC) cells lines and establish the possible mechanisms linked with ...
Merkel Cell Carcinoma and Rare Appendageal Tumors: Overview, Tumors of the Epidermis, Tumorlike Lesions of Fibrous or Elastic...
Cutaneous tumors encompass a vast array of malignancies, from neuroendocrine to lymphoid. In addition to primary malignancies, ... Moyer KE, Banducci DR, Graham WP 3rd, Ehrlich HP. Dupuytrens disease: physiologic changes in nodule and cord fibroblasts ... encoded search term (Merkel Cell Carcinoma and Rare Appendageal Tumors) and Merkel Cell Carcinoma and Rare Appendageal Tumors ... clear cell carcinoma, and mucinous carcinoma.  All these tumors have the capacity to metastasize to skin and regional ...
In vitro inhibitory effects of lentinan on rat glioma cells.
... for Ehrlich carcinoma. According lentinan has no direct effect on killing tumor cells in vivo, it can enhance the bodys immune ... of the tumor, as well as the maximum tumor plane in sagittal scan and height (H). According to these indices, the tumor ... Tumor growth of treatment groups. As shown in Figure 1, intracranial tumor in situ was successfully implanted, and conducted ... Immunohistochemical detection of tumor tissues. The rats were killed on the 21th day after treatment. The tumor tissues were ...
Molecular Biology (BMBB) - Research output - [email protected]
Ehrlich Tumor Carcinoma 66% * Ascites 59% * Growth 30% * Neoplasms 19% 35 Scopus citations ... DNA transfer from Agrobacterium to plant cells in crown gall tumor disease.. Das, A., 1998, In: Sub-cellular biochemistry. 29, ... Antiangiogenic and proapoptotic activities of allyl isothiocyanate inhibit ascites tumor growth in vivo. Kumar, A., DSouza, S ...
Influence of halloysite nanotubes on the efficiency of Asparaginase against mice Ehrlich solid carcinoma. | Saudi J Biol Sci...
It promoted the ASNase to inhibit the adverse effect of ANases on the liver and remove the tumour cells. ... Ehrlich ascites carcinoma; ESC, Ehrlich Solid Carcenoma; HNTs, Halloysite Nanotubes; Halloysite nanotubes, Cancer; ... Influence of halloysite nanotubes on the efficiency of Asparaginase against mice Ehrlich solid carcinoma. ... halloysite nanotubes have demonstrated effective removal of Ehrlich solid carcinoma in mice using an ASNase delivery system. ...
Publications | Laser Dynamics Lab
DeCS 2008 - versión 17 de Marzo de 2008
Purple Lapacho Anti-Cancer
Lapacho have been found to suppress tumor formation and reduce tumor viability. ... Walker carcinosarcoma 256 and Ehrlich solid carcinoma) and Ehrlich ascites cell tumors. Such research then took a gigantic ... including adeno-carcinoma of the liver, breast and prostate and squamous-cell carcinoma of the palate and uterine cervix. Taken ... Some constituents or groups of constituents of lapacho have indeed been found to suppress tumor formation and reduce tumor ...
Search | SciELO
A Comprehensive Review on Food and Medicinal Prospects of Astraeus hygrometricus | FullTxt.Org
on Ehrlichs ascites carcinoma cells. Dig J Nanomater Biostruct. 2012;7(1):185-91 ... It was noted that administration of AE2 to tumour-bearing mice significantly reduced the tumour growth, prolonged their ... Protein A-Activated Macrophages Induce Apoptosis in Ehrlichs Ascites Carcinoma Through a Nitric Oxide-Dependent Pathway. ... activation had an inhibitory effect on various types of cancers including Ehrlichs ascites carcinoma.99,100 This might be an ...
Disease - ca Index | CureHunter Mobile
Carcinoma, Cribriform Carcinoma, Ductal Carcinoma, Ductal, Breast Carcinoma, Ductal, Pancreatic Carcinoma, Ehrlich Tumor ... Carcinoma Carcinoma 256, Walker Carcinoma in Situ Carcinoma of Endocrine Gland Carcinoma of Endometrium Carcinoma, Acinar ... Carcinoma, Small Cell Carcinoma, Small Cell Lung Carcinoma, Spindle Cell Carcinoma, Spindle-Cell Carcinoma, Squamous Carcinoma ... Carcinoma, Islet Cell Carcinoma, Krukenberg Carcinoma, Large Cell Carcinoma, Lewis Lung Carcinoma, Lobular Carcinoma, Male ...
Publications | Laser Dynamics Lab
Publications | Laser Dynamics Lab
A review on anticancer potential of Berberis aristata and berberine with focus on quantitative methods Rokade M, Vichare V,...
evaluate the antineoplastic activity of extracts of BA in ehrlich ascites carcinoma bearing mice using cisplatin as positive ... It was found that ethanolic extract increases the weight due to tumor cell proliferation and also survival time when compared ... Anticancer activity of Berberis aristata in ehrlich ascites carcinoma-bearing mice: A preliminary study. Pharm Biol 2012;50:270 ... The cytotoxicity was carried out using BSL test, the cisplatin and extracts reversed the tumor-induced alteration in total WBCs ...
Levobupivacaine inhibits proliferation and promotes apoptosis of breast cancer cells through PI3K/Akt/mTOR signalling pathway. ...
Objective This study aimed to test the hypothesis that levobupivacaine has anti-tumour effects on breast cancer cells Results ... Effect of local anaesthetic ropivacaine on the energy metabolism of Ehrlich ascites tumour cells. Oncol Res, 1998; 10:491e8. ... Lidocaine Induces Apoptosis and Suppresses Tumour Growth in Human Hepatocellular Carcinoma Cells In Vitro and in a Xenograft ... A study of interleukin 6 (IL-6) and tumour necrosis factor-alpha (TNF-α) serum levels in rats subjected to faecal peritonitis ...
SquamousAscites carcinoma in miceMiceHepatocellular carcinomaSolid tumorsUpper aerodigestive tractAnti-tumor activityCancerSuppressor genesSuppresses tumorPromoter methylationAnticancerBiomarkersMethylationMalignant tumorBreast carcinomaCellsPrognosisSignificant antitumorBrain tumorCutaneousHNSCCRenalHuman chorionic goExperimentalProgressionHydroxychloroquineTesticularSerumGrowthDescriptorMetastasisPatternsChemotherapyCell cultures
- KA lesions can easily be mistaken for squamous cell carcinoma (SCC). (medscape.com)
- [ 7 ] In KAs, cells that stain positive with proliferating-cell nuclear antigen immunostaining are distributed only in the outer edges of the tumor, corresponding to the proliferating squamous epithelial cells. (medscape.com)
- In one clinical study, South American researchers administered lapacho to patients with various forms of cancer, including adeno-carcinoma of the liver, breast and prostate and squamous-cell carcinoma of the palate and uterine cervix. (fasting.ws)
- Patients with advanced inoperable melanoma, cutaneous/head and neck squamous cell or adenoid cystic carcinoma and at least one lesion accessible for IT injection are eligible. (esmo.org)
- Deletion of 8p23.2 or reduced expression of CSMD1 has been associated with poor prognosis in head and neck squamous cell carcinomas and in prostate cancers [2,5,8]. (mindunwindart.com)
- While CSMD1 transcripts are detectable in upper aerodigestive tract epithelium, preliminary analysis of several head and neck squamous cell carcinoma cellular lines recommended that CSMD1 appearance was dropped in these lines . (mindunwindart.com)
- Although the spot that contains CSMD1 is certainly often removed in throat and mind squamous cellular carcinomas and prostatic adenocarcinomas [3,11-15], stage mutations within the gene are fairly rare in principal squamous malignancies  and in squamous cellular carcinoma cellular lines (Schmidt, Scholnick and Richter, unpublished). (mindunwindart.com)
- Within this paper, we demonstrate that some squamous cellular carcinoma cellular lines usually do not exhibit full duration CSMD1 transcripts, all produce unusual transcripts improbable to encode useful CSMD1 proteins almost. (mindunwindart.com)
- Used jointly these data show that mechanisms apart from stage mutation are 89464-63-1 in charge of the aberrant CSMD1 appearance in mind and throat squamous cell carcinoma cell lines, and these data suggest potential targets for further investigation in main tumors. (mindunwindart.com)
- Integrative and comparative genomic analysis of HPV-positive and HPV-negative head and neck squamous cell carcinomas. (uchicago.edu)
- In this patient, who had a T4N2cM0 squamous cell carcinoma of the oropharynx, an apron flap was elevated that extended from 1 mastoid tip to the other. (medscape.com)
- Actinic keratoses may remain unchanged, spontaneously resolve, or progress to invasive squamous cell carcinoma. (medscape.com)
- Additionally, actinic keratoses can be clinically indistinguishable from more serious cutaneous malignancies, including squamous cell carcinoma and lentigo maligna. (medscape.com)
- Lesions may progress into invasive squamous cell carcinomas. (medscape.com)
- Epidemiology of actinic keratoses and squamous cell carcinoma. (medscape.com)
- Inflammation is associated with progression of actinic keratoses to squamous cell carcinomas in humans. (medscape.com)
- Prognosis of patients with advanced head and neck squamous cell carcinomas (HNSCC) is still poor. (iozk.de)
- Characterization of Epigenomic Alterations in HPV16+ Head and Neck Squamous Cell Carcinomas. (cdc.gov)
- The expression and methylation of PITX genes is associated with the prognosis of head and neck squamous cell carcinoma. (cdc.gov)
- Differentially methylated genes in proliferative verrucous leukoplakia reveal potential malignant biomarkers for oral squamous cell carcinoma. (cdc.gov)
- Clinical performance validation of PITX2 DNA methylation as prognostic biomarker in patients with head and neck squamous cell carcinoma. (cdc.gov)
Ascites carcinoma in mice2
- A novel kefir product (PFT) inhibits Ehrlich ascites carcinoma in mice via induction of apoptosis and immunomodulation. (greenmedinfo.com)
- Egyptian propolis contains a higher level of flavonoids, phenolics, and dihydroflavonoids in propolis extract, and it has anticancer effects in vitro studies and inhibits tumor development in Ehrlich ascites carcinoma in mice model. (totokr.com)
- IMSEAR at SEARO: Evaluation of anti-tumor efficacy of injectable Centchroman in mice bearing Ehrlich ascites carcinoma. (who.int)
- Anti-tumor efficacy of Centchroman formulated as niosomes and gel implant was evaluated in Swiss albino mice bearing Ehrlich ascites carcinoma at 10 mg/kg body weight dose given subcutaneously. (who.int)
- Anticancer and apoptogenic effect of graviola and low-dose radiation in tumor xenograft in mice. (greenmedinfo.com)
- In vivo testing of 400 mg/kg OT or dehydroepiandrosterone-sulfate in C57BL/6 mice hosting Ehrlich's ascitic tumor cells revealed a 90.4 and a 46% decrease in the final tumor mass after 3 days of treatment. (nih.gov)
- In tumour-bearing mice, WSF inhibited the expression of pStat-3, with a selective stimulation of Th1 immunity as evidenced by enhanced secretion of IFN-gamma and IL-2. (mcw.edu)
- In addition, WSF also enhanced T cell activation in camptothecin treated tumour-bearing mice. (mcw.edu)
- The aim of the present study was to characterize the Ehrlich tumor as a model of lymphatic metastasis in mice. (usp.br)
- Methods: In vivo anticancer activity was evaluated against EAC cells bearing Swiss albino mice by monitoring parameters such as tumor cell proliferation, tumor weight measurement, and survival time etc. (edu.au)
- M. champaca bark also altered the depleted hematological parameters such as red blood cell, white blood cell, hemoglobin (Hb%) towards normal in tumor bearing mice. (edu.au)
- Influence of halloysite nanotubes on the efficiency of Asparaginase against mice Ehrlich solid carcinoma. (bvsalud.org)
- In conclusion, halloysite nanotubes have demonstrated effective removal of Ehrlich solid carcinoma in mice using an ASNase delivery system. (bvsalud.org)
- When TNF-α levels w ere measured in mice bearing the S-180 carcinoma, mice treated with TCM-EF showed slightly higher TNF-α levels as compared to the control group. (skku.edu)
- The antitumor effect of an organic germanium compound, carboxyethylgermanium sesquioxide (Ge-132), was examined in mice using two systems: one, the ascitic form of Ehrlich carcinoma in DDI mice, and the other, the solid form of Meth-A fibrosarcoma in BALB/c mice. (greenmedinfo.com)
- In the mice with Ehrlich ascitic tumors, a remarkable prolongation in life span was observed after intraperitoneal (i.p.) or per oral (p.o.) administration of Ge-132 (300 mg/kg), but not after intravenous (i.v.) injection of the same compound. (greenmedinfo.com)
- When the in vivo effect of these in vitro active Mø was examined after adoptive transfer to mice bearing Ehrlich ascitic tumor cells, a significant antitumor effect was noted. (greenmedinfo.com)
- In the mice bearing solid Meth-A tumors, i.v. injections of Ge-132 (100 mg/kg) were found to inhibit tumor growth remarkably, although i.p. and p.o. administrations did not have the same result. (greenmedinfo.com)
- When the mice which had recovered from Meth-A tumor growth, following i.v. injections of Ge-132, were challenged with the same tumor on day 30, all mice were able to tolerate the challenge, but nota challenge of RL male 1 tumor cells. (greenmedinfo.com)
- Alnustone, a diarylheptane compound, exhibits potent growth inhibition against hepatocellular carcinoma (HCC) BEL‐7402 cells. (usda.gov)
- hepatitis viruses B and C are associated with hepatocellular carcinoma (Monto and Wright 2001 ), Simian virus 40 has been linked to mesothelioma (Rizzo et al. (biomedcentral.com)
- Animal research in the United States made a gigantic stride forward when it was discovered that lapacho inhibited solid tumors (Walker carcinosarcoma 256 and Ehrlich solid carcinoma) and Ehrlich ascites cell tumors. (fasting.ws)
- This phase I study is evaluating IT injection of CV8102 alone or in combination with a systemic anti-PD-1 antibody in patients with advanced solid tumors. (esmo.org)
Upper aerodigestive tract1
- History CUB and Sushi Multiple Domains 1 ( CSMD1 ) was cloned as an applicant tumor suppressor or development gene from an area of individual chromosome 8 deleted in tumors of the upper aerodigestive tract, prostate, ovary and bladder [1-7]. (mindunwindart.com)
- According lentinan has no direct effect on killing tumor cells in vivo, it can enhance the body's immune function to display anti-tumor activity [ 8 ]. (alliedacademies.org)
- In the lactic acid bacteria in the gut, we directed our attention to TCM-EF, which have been known as using the bacteria death of lactic acid bacteria by heat treatment, and examined the mechanisms by which these substances affect antioxidant activity, anti-tumor activity and immunoresponse. (skku.edu)
- Thus, TCM-EF showed strong anti-tumor activity against two kinds of solid carcinoma. (skku.edu)
- In a syngeneic murine model, intratumoral (IT) delivery of CV8102 induced dose-dependent anti-tumor activity and synergized with systemic anti-PD1 antibody treatment. (esmo.org)
- Demonstration of the ability to self-renew, a key feature of stem cells, is achieved through serial passage of tumors in xenohosts, and the impact of cancer stem cells on the practice of medicine is likely to be profound. (semanticscholar.org)
- The capacity of single embryonal carcinoma cells to differentiate into benign tissues supports neither the dogma of the irreversibility of the malignant transformation nor the somatic cell mutation theory of cancer. (semanticscholar.org)
- Lung cancer is one of the most common types of malignant tumor. (usda.gov)
- Lentinan has a strong inhibitory effect on cancer cells, with inhibition rates of 97.5% for mouse sarcoma 180 and 80% for Ehrlich carcinoma . (alliedacademies.org)
- The present study aimed to investigate the anti-tumour effects of levobupivacaine on breast cancer cells. (researchsquare.com)
- Fisher, Fisher: 'Host-tumor relationship in the development and growth of hepatic metastases' In: Wissler, Dao, Wood: 'Endogenous Factors Influencing Host-Tumor Balance, International Symposium Sponsored by the Argonne Cancer Research Hospital, University of Chicago 149-166 1966 University of Chicago Press 1967 Bild von 5000 Tumorzellen und Faktoren die Wachstum beschleunigen und Wachstum hemmen. (50g.com)
- Local activation of innate immune signaling pathways, such as Toll-like Receptors (TLRs) or RIG-I-like Receptors (RLRs), is a promising cancer immunotherapeutic approach to overcome the tumor immunosuppressive microenvironment and to induce/restore anti-tumor immunity. (esmo.org)
- We hypothesize that hyperglycemia provides a nutrient-rich, growth signal-rich environment for epithelial ovarian cancer cells, where tumour formation and growth is encouraged by free radical-induced DNA damage. (hindawi.com)
- Retine, or alpha-ketoaldehyde, inhibits the growth of certain types of cancer, including sarcoma 180 and Ehrlich carcinoma. (mycoldiscovery.com)
- 1999) found agglutinin cytotoxic or inhibit tumor cells in LS174T, SW1222 and HT human colon cancer cells. (mycoldiscovery.com)
- Tumor suppressor genes are expected to be inactivated in cancers either genetically by mutations or epigenetically by modification of their promoters. (mindunwindart.com)
- Activation of oncogenes or silencing of tumor suppressor genes may be the result of long lasting inflammation. (biomedcentral.com)
- Taken altogether, this strongly suggests that TCM-EF enhances original functions of macrophages and NK cells, and as a result, secondarily enhances the immune reaction and suppresses tumor growth. (skku.edu)
- Thus, gene promoter methylation induced by JCV may be an important process in CRC and the polyp-carcinoma sequence. (biomedcentral.com)
- Significance of PITX2 Promoter Methylation in Colorectal Carcinoma Prognosis. (cdc.gov)
- Anticancer effects of combination of indole-3-carbinol and hydroxychloroquine on ehrlich ascites carcinoma. (greenmedinfo.com)
- Therefore, enzymes or substrates regulating the nonoxidative synthesis of ribose could also be the sites to preferentially target tumor cell proliferation by new anticancer drugs. (nih.gov)
- The primary objective is to determine safety and tolerability, secondary/explorative objectives are to evaluate tumor response and changes in tumor tissue and blood-based biomarkers. (esmo.org)
- Fig. 1: Developmental biology as a driver for uncovering testicular germ cell tumour biomarkers. (nature.com)
- The association of CRC hMLH1 methylation and tumor positivity for JCV was recently documented. (biomedcentral.com)
- A transplantable, poorly differentiated malignant tumor which appeared originally as a spontaneous breast carcinoma in a mouse. (bvsalud.org)
- The IC 50 values showed that this effect was more intense on breast normal cells (MCF-10A) than on breast carcinoma cells (MCF-7 and 4T1). (biomedcentral.com)
- The treatment with rhodium (II) citrate-loaded maghemite nanoparticles and magnetoliposomes induced more specific cytotoxicity on breast carcinoma cells than on breast normal cells, which is the opposite of the results observed with free Rh 2 (H 2 cit) 4 treatment. (biomedcentral.com)
- Breast carcinoma represents the major cause of death among women worldwide. (biomedcentral.com)
- Cytological investigations based on morphological and statisticzl analysis of the chromosomes in several ascites tumors of rats conducted by the present author in collaboratioii with his co-workers have revealed tlie existence of the stem line (or stem lines) of tumor cells as primary contributors to the growth of the tumor. (semanticscholar.org)
- It would appear that the progeny of malignant stem cells can differentiate into postmitotic benign cells incapable of forming a tumor. (semanticscholar.org)
- Deregulated apoptosis and suppressed tumour reactive immunity render tumour cells to grow amok in the host body. (mcw.edu)
- Animals were inoculated into the footpad and the popliteal lywph nodes were collected at several times post-inoculation in order to evaluate their weight, histopathological aspects,and mast cells quantitation, since these cells are reported to be implicated in host's response to tumor. (usp.br)
- The migration of tumor cells was detected by a biological assay as early as 1 hour post-inoculation. (usp.br)
- Objective: In the present study, stem-bark of Mycelia champaca is subjected to evaluate its anti-proliferative effect against Ehrlich ascites carcinoma (EAC) cells. (edu.au)
- Group 1 ( control ), Group 2 (ESC group) of a single dose of 0.15 ml Ehrlich cells (2 × 106) intraperitoneal infusion (IP), Group 3 (ESC + ANase group) received six doses equal treatments of Intratumoral (IT) 0.07 ml Aspragnase (7 mg/kg) over two weeks. (bvsalud.org)
- It promoted the ASNase to inhibit the adverse effect of ANase's on the liver and remove the tumour cells . (bvsalud.org)
- Superparamagnetic particles of iron oxide (SPIOs) represent an attractive platform as carriers in drug delivery systems (DDS) because they can present greater specificity to tumor cells than normal cells. (biomedcentral.com)
- Thus, magnetic nanoparticles represent an attractive platform as carriers in Rh 2 (H 2 cit) 4 delivery systems, since they can act preferentially in tumor cells. (biomedcentral.com)
- Ursolic acid having anti-mutagenic nature has the potential to induce apoptosis in tumor cells as well as to prevent malignant transformation of normal cells [ 12 ]. (genominfo.org)
- Urine cytology showed malignant cells strongly suspicious for adenocarcinoma which correlated with the biopsy findings where immunohistochemistry demonstrated carcinoma with glandular differentiation and positivity for cytokeratin (CK) 20, fully compatible with a metastatic colonic type adenocarcinoma. (docksci.com)
- It is their activity, how well they recognize and find tumor cells, that is most important. (mycoldiscovery.com)
- Vaccine was prepared from the tumor cell cultures of patients by infection of the cells with Newcastle Disease Virus, followed by gamma-irradiation, and vaccine was applied up to five times. (iozk.de)
- Immune monitoring revealed significant increases of antitumor delayed type hypersensitivity reactivity especially in disease-free patients, and in a significant proportion of vaccinated patients the presence of tumor-reactive T-cells in the peripheral blood even 5 to 7 years after the last vaccination. (iozk.de)
- Postoperative vaccination with virus-modified autologous tumor cells seems to be feasible and safe and may improve the prognosis of HNSCC patients with advanced tumors. (iozk.de)
- Glioma is the most common primary brain tumor, but the treatment is troublesome and the prognosis is poor due to invasive growth [ 4 ]. (alliedacademies.org)
- Rhodium (II) citrate (Rh 2 (H 2 cit) 4 ) has significant antitumor, cytotoxic, and cytostatic activity on Ehrlich ascite tumor. (biomedcentral.com)
- Predicting neurocognitive function in pediatric brain tumor early survivorship: The neurological predictor scale and the incremental validity of tumor size. (mdanderson.org)
- Cutaneous tumors encompass a vast array of malignancies, ranging from neuroendocrine to lymphoid in origin. (medscape.com)
- The diagnosis and treatment of these cutaneous tumors is constantly evolving, and the role of clinicians relies on accurate diagnosis and a thorough understanding of the clinical sequelae. (medscape.com)
- The origin of cutaneous tumors can be simplistically divided into three major categories: epidermal, dermal, and adnexal (see image below). (medscape.com)
- Therefore, we analyzed whether antitumor vaccination with a virus-modified autologous tumor cell vaccine is feasible and safe in HNSCC patients. (iozk.de)
- Progression of two of the three transplantable Morris renal tumors: study of histology, ultrastructure and chromosome banding patterns. (semanticscholar.org)
- He has been a member of the Children's Oncology Group Renal Committee for the past decade and has reviewed the radiotherapy fields and doses in children with Wilms' tumors treated in the previously opened Renal studies. (mdanderson.org)
Human chorionic go1
- For decades, clinical management of patients with TGCT has relied on classic serum tumour markers: α-fetoprotein, human chorionic gonadotropin subunit-β and lactate dehydrogenase. (nature.com)
- These findings are discussed in regard to the experimental use of ascites tumor populations. (aacrjournals.org)
- Some constituents or groups of constituents of lapacho have indeed been found to suppress tumor formation and reduce tumor viability, both in experimental animal trials and in clinical settings involving human patients. (fasting.ws)
- A yellow Himalayan raspberry extract was effective in wound healing and reduction of tumor progression. (greenmedinfo.com)
- Resveratrol is a polyphenol isolated from the grapes skin, shown to alter both cell cycle progression and the cytotoxic response to ionizing radiation in cervical tumor cell lines [ 13 ]. (genominfo.org)
- If hyperglycemia contributes to tumour growth and progression, then it is intuitive that antihyperglycemic drugs may also have an important antitumour role. (hindawi.com)
- This study aimed to assess I3C antineoplastic activity alone and with hydroxychloroquine (HCQ) on Ehrlich ascites carcinoma (EAC) model. (usda.gov)
- A basis is established for the occurrence of multiple types of testicular tumor in one testis and for the histogenesis of the various germinal tumors of the testicle. (semanticscholar.org)
- In the past 10 years, microRNAs have been shown to outperform classic serum tumour markers in the diagnosis of primary tumours and in follow-up monitoring and prediction of relapse. (nature.com)
- Fig. 2: Sensitivity of the classic serum tumour markers AFP, β-HCG and LDH in detecting TGCT compared with miRNA-based markers (all miRNA tests considered). (nature.com)
- This study investigates the significance of the glucose-6-phosphate dehydrogenase (G6PD) catalyzed oxidative and the transketolase (TK) catalyzed nonoxidative pentose cycle (PC) reactions in the tumor proliferation process by characterizing tumor growth patterns and synthesis of the RNA ribose moiety in the presence of respective inhibitors of G6PD and TK. (nih.gov)
- WSF at 150mg/kg, i.p., inhibited >50% tumour growth in the mouse tumour models. (mcw.edu)
- The solid tumor growth in the footpad was measured until day 30 post-inoculation and the histological alterations during this period were also studied. (usp.br)
- Our understanding of the interrelationship between nutrition, immunology, oncogenesis, and tumor growth is steadily increasing. (caninebiologics.com)
- The combined action of the LiCl(I)-I2-a-dextrin-peptide complex drug and doxorubicin on the growth of Ehrlich ascites carcinoma (EAC) has been shown to significantly enhance doxorubicin's antitumor function. (2pressrelease.net)
- Tumor Virus Infections" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uchicago.edu)
- Ehrlich tumor was considered as a suitable model for the study of lymphatic metastasis. (usp.br)
- The differential diagnosis of ureteral adenocarcinoma, especially in patients with previous history of colon adenocarcinoma, should include the possibility of distant metastasis from the primary colonic tumor. (docksci.com)
- In the Lettré-Ehrlich strain, the patterns of DNA distribution in the population and of chromosome number were constant and of the type expected from the work of others and from theoretical considerations. (aacrjournals.org)
- Outcomes based on histopathologic response to preoperative chemotherapy in children with bilateral Wilms tumor: A prospective study (COG AREN0534). (mdanderson.org)
- In this work, we report the cytotoxicity of free rhodium (II) citrate (Rh 2 (H 2 cit) 4 ) and rhodium (II) citrate-loaded maghemite nanoparticles or magnetoliposomes, used as drug delivery systems, on both normal and carcinoma breast cell cultures. (biomedcentral.com)
- Establishment of tumor cell cultures was successful in about 80% of the cases. (iozk.de)