Carcinoma, Basosquamous: A skin carcinoma that histologically exhibits both basal and squamous elements. (From Dorland, 27th ed)Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm but is often wrongly used as a synonym for "cancer." (From Dorland, 27th ed)Carcinoma, Basal Cell: A malignant skin neoplasm that seldom metastasizes but has potentialities for local invasion and destruction. Clinically it is divided into types: nodular, cicatricial, morphaic, and erythematoid (pagetoid). They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck area and the remaining 15% on the trunk and limbs. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1471)Skin Neoplasms: Tumors or cancer of the SKIN.Bowen's Disease: A persistent progressive non-elevated red scaly or crusted plaque which is due to an intradermal carcinoma and is potentially malignant. Atypical squamous cells proliferate through the whole thickness of the epidermis. The lesions may occur anywhere on the skin surface or on mucosal surfaces. The cause most frequently found is trivalent arsenic compounds. Freezing, cauterization or diathermy coagulation is often effective. (From Rook et al., Textbook of Dermatology, 4th ed, pp2428-9)Keratosis: Any horny growth such as a wart or callus.Sunlight: Irradiation directly from the sun.Carcinoma, Squamous Cell: A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)Sunburn: An injury to the skin causing erythema, tenderness, and sometimes blistering and resulting from excessive exposure to the sun. The reaction is produced by the ultraviolet radiation in sunlight.Nevus: A circumscribed stable malformation of the skin and occasionally of the oral mucosa, which is not due to external causes and therefore presumed to be of hereditary origin.Neurocutaneous Syndromes: A group of disorders characterized by ectodermal-based malformations and neoplastic growths in the skin, nervous system, and other organs.Mongolian Spot: A bluish-gray to gray-brown benign, melanocytic nevus found usually in the LUMBOSACRAL REGION of dark-skinned people, especially those of East Asian ancestry. It is usually congenital or appears shortly after birth, and disappears in childhood.Nevus of Ota: A macular lesion on the side of the FACE, involving the CONJUNCTIVA and EYELIDS, as well as the adjacent facial skin, SCLERA; OCULOMOTOR MUSCLES; and PERIOSTEUM. Histological features vary from those of a MONGOLIAN SPOT to those of a BLUE NEVUS.Nevus, Sebaceous of Jadassohn: A syndrome characterized by lesions occurring on the face, scalp, or neck which consist of congenital hypoplastic malformations of cutaneous structures and which over time undergo verrucous hyperplasia. Additionally it is associated with neurological symptoms and skeletal, ophthalmological, urogenital, and cardiovascular abnormalities.DNA Breaks, Double-Stranded: Interruptions in the sugar-phosphate backbone of DNA, across both strands adjacently.Ochratoxins: Isocoumarins found in ASPERGILLUS OCHRACEUS and other FUNGI. Ochratoxin contaminated FOOD has been responsible for cases of FOODBORNE DISEASES.Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.Keratosis, Actinic: White or pink lesions on the arms, hands, face, or scalp that arise from sun-induced DNA DAMAGE to KERATINOCYTES in exposed areas. They are considered precursor lesions to superficial SQUAMOUS CELL CARCINOMA.Photosensitizing Agents: Drugs that are pharmacologically inactive but when exposed to ultraviolet radiation or sunlight are converted to their active metabolite to produce a beneficial reaction affecting the diseased tissue. These compounds can be administered topically or systemically and have been used therapeutically to treat psoriasis and various types of neoplasms.Syringoma: A benign tumor of the sweat glands which is usually multiple and results from malformation of sweat ducts. It is uncommon and more common in females than in males. It is most likely to appear at adolescence, and further lesions may develop during adult life. It does not appear to be hereditary. (Rook et al., Textbook of Dermatology, 4th ed, pp2407-8)Sweat Gland NeoplasmsElectrosurgery: Division of tissues by a high-frequency current applied locally with a metal instrument or needle. (Stedman, 25th ed)Adenoma, Pleomorphic: A benign, slow-growing tumor, most commonly of the salivary gland, occurring as a small, painless, firm nodule, usually of the parotid gland, but also found in any major or accessory salivary gland anywhere in the oral cavity. It is most often seen in women in the fifth decade. Histologically, the tumor presents a variety of cells: cuboidal, columnar, and squamous cells, showing all forms of epithelial growth. (Dorland, 27th ed)Umbilicus: The pit in the center of the ABDOMINAL WALL marking the point where the UMBILICAL CORD entered in the FETUS.Operating Tables: A raised flat surface on which a patient is placed during surgical procedures.Electromagnetic Fields: Fields representing the joint interplay of electric and magnetic forces.Endocrinology: A subspecialty of internal medicine concerned with the metabolism, physiology, and disorders of the ENDOCRINE SYSTEM.Drug Information Services: Services providing pharmaceutic and therapeutic drug information and consultation.Newspapers: Publications printed and distributed daily, weekly, or at some other regular and usually short interval, containing news, articles of opinion (as editorials and letters), features, advertising, and announcements of current interest. (Webster's 3d ed)Mohs Surgery: A surgical technique used primarily in the treatment of skin neoplasms, especially basal cell or squamous cell carcinoma of the skin. This procedure is a microscopically controlled excision of cutaneous tumors either after fixation in vivo or after freezing the tissue. Serial examinations of fresh tissue specimens are most frequently done.Cardiac Imaging Techniques: Visualization of the heart structure and cardiac blood flow for diagnostic evaluation or to guide cardiac procedures via techniques including ENDOSCOPY (cardiac endoscopy, sometimes refered to as cardioscopy), RADIONUCLIDE IMAGING; MAGNETIC RESONANCE IMAGING; TOMOGRAPHY; or ULTRASONOGRAPHY.Dermatology: A medical specialty concerned with the skin, its structure, functions, diseases, and treatment.Dermatologic Surgical Procedures: Operative procedures performed on the SKIN.Societies, Medical: Societies whose membership is limited to physicians.Nuclear Medicine: A specialty field of radiology concerned with diagnostic, therapeutic, and investigative use of radioactive compounds in a pharmaceutical form.Sodium Nitrite: Nitrous acid sodium salt. Used in many industrial processes, in meat curing, coloring, and preserving, and as a reagent in ANALYTICAL CHEMISTRY TECHNIQUES. It is used therapeutically as an antidote in cyanide poisoning. The compound is toxic and mutagenic and will react in vivo with secondary or tertiary amines thereby producing highly carcinogenic nitrosamines.Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)Carcinogenicity Tests: Tests to experimentally measure the tumor-producing/cancer cell-producing potency of an agent by administering the agent (e.g., benzanthracenes) and observing the quantity of tumors or the cell transformation developed over a given period of time. The carcinogenicity value is usually measured as milligrams of agent administered per tumor developed. Though this test differs from the DNA-repair and bacterial microsome MUTAGENICITY TESTS, researchers often attempt to correlate the finding of carcinogenicity values and mutagenicity values.Rats, Inbred F344Water: A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Pathology: A specialty concerned with the nature and cause of disease as expressed by changes in cellular or tissue structure and function caused by the disease process.OhioApolipoproteins D: A glycoprotein component of HIGH-DENSITY LIPOPROTEINS that transports small hydrophobic ligands including CHOLESTEROL and STEROLS. It occurs in the macromolecular complex with LECITHIN CHOLESTEROL ACYLTRANSFERASE. Apo D is expressed in and secreted from a variety of tissues such as liver, placenta, brain tissue and others.Pilomatrixoma: A tumor composed of cells resembling those of the hair matrix, which undergo 'mummification' and may calcify. It is a relatively uncommon tumor, which may occur at any age from infancy. The majority of patients are under 20, and females are affected more than males. The lesion is usually a solitary deep dermal or subcutaneous tumor 3-30 mm in diameter, situated in the head, neck, or upper extremity. (From Rook et al., Textbook of Dermatology, 4th ed, p2401)Search Engine: Software used to locate data or information stored in machine-readable form locally or at a distance such as an INTERNET site.Carcinoembryonic Antigen: A glycoprotein that is secreted into the luminal surface of the epithelia in the gastrointestinal tract. It is found in the feces and pancreaticobiliary secretions and is used to monitor the response to colon cancer treatment.Bibliometrics: The use of statistical methods in the analysis of a body of literature to reveal the historical development of subject fields and patterns of authorship, publication, and use. Formerly called statistical bibliography. (from The ALA Glossary of Library and Information Science, 1983)HungaryPublications: Copies of a work or document distributed to the public by sale, rental, lease, or lending. (From ALA Glossary of Library and Information Science, 1983, p181)Research: Critical and exhaustive investigation or experimentation, having for its aim the discovery of new facts and their correct interpretation, the revision of accepted conclusions, theories, or laws in the light of newly discovered facts, or the practical application of such new or revised conclusions, theories, or laws. (Webster, 3d ed)Biomedical Research: Research that involves the application of the natural sciences, especially biology and physiology, to medicine.Academies and Institutes: Organizations representing specialized fields which are accepted as authoritative; may be non-governmental, university or an independent research organization, e.g., National Academy of Sciences, Brookings Institution, etc.PubMed: A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.

Expression of Bcl-2 and amplification of c-myc are frequent in basaloid squamous cell carcinomas of the esophagus. (1/23)

Basaloid squamous cell carcinoma (BSCC) of the esophagus is a rare, poorly differentiated variant of typical esophageal squamous cell carcinoma (SCC) characterized by high proliferative activity and frequent spontaneous apoptoses. In the present study, we investigated the expression of the apoptosis-suppressing protein Bcl-2 in 23 BSCC of the esophagus and 23 stage-matched typical esophageal SCC by means of immunohistochemistry. In addition, amplification of the apoptosis- and proliferation-inducing gene c-myc was determined by means of differential polymerase chain reaction. Bcl-2 expression was found significantly more often in BSCC than in SCC (86.9% vs. 17.4%, P < 0.0001). Amplification of c-myc was nearly twice as common in BSCC as in SCC (47.8% vs. 26.1%, not significant). Bcl-2 protein expression together with c-myc amplification was detected in 43.5% of the BSCC but in none of the typical SCC (P < 0.0001). Taken together, our findings indicate that the molecular pathogenesis of esophageal BSCC differs from that of typical SCC and frequently involves coactivation of c-myc and Bcl-2.  (+info)

Detection of circulating anti-p53 antibodies in esophageal cancer patients. (2/23)

It has been reported that circulating anti-p53 antibodies (p53-Ab) in the serum are detected in some cancers. To investigate the usefulness of detecting p53-Ab, we measured the circulating p53-Ab in comparison with squamous cell carcinoma antigen (SCC-Ag) in patients with esophageal carcinoma. Serum specimens from 46 esophageal cancer patients (42 squamous cell carcinomas, 3 mucoepidermoid carcinomas and 1 basaloid squamous carcinoma) and 13 healthy subjects were studied. Serum p53-Ab was measured by an enzyme-linked immunosorbent assay. Surgically resected specimens from 43 patients were immunohistochemically stained for p53. Serum SCC-Ag was measured by a radioimmunoassay. The results were analyzed with the clinical data and outcome. Serum p53-Ab was detected in 13 (28%) of the 46 patients, but not in any of the healthy subjects. The positive rate was 0% (0/6) in stage I, 60% (3/5) in stage IIA, 30% (3/10) in stage IIB, 29% (7/24) in stage III and 0% (0/1) in stage IV. There was no difference in the outcome between the p53-Ab-positive and p53-Ab-negative patients. Immunohistochemically, 30 (70%) of the 43 specimens stained positively for p53. Serum p53-Ab was detected in 43% (13/30) of the patients with tumors which stained positively for p53. There was a close correlation between positivity for p53 immunostaining and positivity for p53-Ab (p<0.01). An elevated level of SCC-Ag was found in only 13%of the patients, and most patients positive for SCC-Ag already had advanced disease with lymph node metastasis and invasion to the adventitia. In conclusion, serum p53-Ab was detected in Japanese esophageal cancer patients at a frequency similar to that reported in Western countries. Serum p53-Ab may be a potentially useful molecular marker for detection and screening of esophageal cancer. Further studies of a large population may be required to elucidate the true diagnostic usefulness of measuring the serum p53-Ab.  (+info)

Delayed hypersensitivity to 5-fluorouracil following topical chemotherapy of cutaneous cancers. (3/23)

Skin tests to various common antigens, dinitrochlorobenzene, and 5-fluorouracil (5-FU) were performed on patients being treated for cutaneous neoplasms with topical 5-FU cream. Eleven of 15 patients tested both before and after therapy converted from skin test negative to positive with respect to 5-FU. This conversion correlated with positive dinitrochlorobenzene skin tests and therapeutic cure. The relation between the induction of delayed hypersensitivity reactions to 5-FU following treatment with topical 5-FU and the cure rate for cutaneous neoplasms showed a trend toward correlation.  (+info)

p63 Immunohistochemistry in the distinction of adenoid cystic carcinoma from basaloid squamous cell carcinoma. (4/23)

Morphologic distinction of high-grade adenoid cystic carcinoma from basaloid squamous cell carcinoma can be difficult. Equivocal diagnoses can mislead treatment. We have investigated the possibility that immunohistochemical staining for the presence of p63, a novel epithelial stem-cell regulatory protein, could be a useful means of distinguishing these two neoplasms. Archival, routinely processed slides were subjected to citrate-based antigen retrieval, exposure to anti-p63 monoclonal 4A4, and developed with a streptavidin-biotin kit and diaminobenzidine as chromogen. p63 was detected in 100% of the adenoid cystic carcinomas (n=14) and 100% of basaloid squamous cell carcinomas (n=16). Basaloid squamous cell carcinomas consistently displayed diffuse p63 positivity, with staining of nearly 100% of tumor cells. In contrast, adenoid cystic carcinoma displayed a consistently compartmentalized pattern within tumor nests. Compartmentalization was manifested in two patterns: (1) selective staining of a single peripheral layer of p63-positive cells surrounding centrally located tumor cells that were p63-negative and (2) tumor nests consisting of multiple contiguous glandular/cribriform-like units of p63-positive cells surrounding or interspersed with p63-negative cells. p63 immunostaining constitutes a specific and accurate means of distinguishing adenoid cystic carcinoma from basaloid squamous cell carcinoma. p63 positivity in adenoid cystic carcinoma appears to be homologous to that seen in the basal and/or myoepithelial compartments of salivary gland and other epithelia, and may signify a stem-cell-like role for these peripheral cells. Diffuse p63 positivity in basaloid squamous cell carcinoma suggests dysregulation of p63-positive stem cells in poorly differentiated squamous carcinoma.  (+info)

Basosquamous carcinoma: treatment with Mohs micrographic surgery. (5/23)

BACKGROUND: Basosquamous carcinoma (BSC) is a rare tumor defined as a basal cell carcinoma (BCC) differentiating into squamous cell carcinoma (SCC). It is reported to have a high rate of recurrence with standard wide local excision. The aim of the current study was to report a large series of patients with BSC treated with Mohs micrographic surgery (MMS). METHODS: The prospective, multicenter case series included all patients in Australia treated with MMS for BSC, who were monitored by the Skin and Cancer Foundation Australia between 1993 and 2002. RESULTS: Most of the 178 tumors (95.6%) were located in the head and neck area. Recurrent tumors occurred in 47.8% of patients. The tumors were diagnosed initially as BCC in 87.4% and as SCC in 12.0% of patients. Perineural invasion was recorded in 7.9% of patients with data available. Most of these (69.0%) were previously recurrent tumors. Of 98 patients who completed a 5-year follow-up period after MMS, 4 (4.1%) had disease recurrence. CONCLUSIONS: The low 5-year disease recurrence rate of BSC with MMS emphasized the importance of margin-controlled excision using MMS.  (+info)

Histologic subtypes of oral squamous cell carcinoma: prognostic relevance. (6/23)

Squamous cell carcinoma (SCC) is the most prevalent malignant neoplasm of the oral cavity. The conventional tumour and several histologic subtypes of SCC present morphologic features and specific behaviour when they occur in the oral mucosa. For example, basaloid SCC is an aggressive tumour and verrucous carcinoma has the lowest invasive and metastatic potential; however, the clinical and biologic course of these oral SCC variants has not been completely established. Furthermore, although numerous clinical and histologic features associated with oral SCC have been identified, none shows unequivocal prognostic significance. The purpose of this article is to review the various subtypes of oral SCC, emphasizing problems in their histologic diagnosis and prognosis.  (+info)

Sarcomatoid carcinoma with a predominant basaloid squamous carcinoma component: the first report of an unusual biphasic tumor of the ureter. (7/23)

Malignant tumors of the ureter that display biphasic patterns are very rare; they include carcinosarcomas, sarcomatoid carcinomas and carcinomas with pseudosarcomatous stroma. Although the distinction between carcinosarcomas and sarcomatoid carcinomas has been extensively discussed in the past, the recent World Health Organization classification of urinary tract tumors (2004) does not distinguish the two lesions and use the term sarcomatoid carcinoma to represent these biphasic tumors. The epithelial components of previously reported ureteral biphasic tumors comprise transitional cell carcinoma, squamous cell carcinoma, carcinoma in situ, small cell carcinoma and adenocarcinoma. In this paper, we report the first case of sarcomatoid carcinoma of the ureter with a predominant basaloid squamous carcinoma component. A 63-year-old man who had developed asymptomatic gross hematuria was diagnosed with a right ureteral tumor and underwent a right nephroureterectomy. Macroscopic examination of the excised tumor revealed a polypoid mass. Histopathologic examination exposed a tumor with malignant epithelial and sarcomatous components. The malignant epithelial component was predominantly composed of basaloid squamous carcinoma, and the sarcomatous component was mostly composed of undifferentiated spindle cells. A small focus of a chondrosarcomatous component was present. There were also transitional zones between the two components. In addition, the spindle cells of the sarcomatous component were partially positive for cytokeratin 7. We believe that the findings of this case study will increase the morphological diversity used for diagnosing malignant tumors of the ureter.  (+info)

Outcomes after radiotherapy for basaloid squamous cell carcinoma of the head and neck: a case-control study. (8/23)

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*International Classification of Diseases for Oncology

NOS M8094/3 Basosquamous carcinoma (C44._) Mixed basal-squamous cell carcinoma M8095/3 Metatypical carcinoma M8096/0 ... NOS Reserve cell carcinoma Round cell carcinoma Small cell neuroendocrine carcinoma M8042/3 Oat cell carcinoma (C34._) M8043/3 ... Renal cell carcinoma, spindle cell M8319/3 collecting duct carcinoma (C64.9) Bellini duct carcinoma Renal carcinoma, collecting ... NOS Condylomatous carcinoma Verrucous squamous cell carcinoma Verrucous epidermoid carcinoma Warty carcinoma M8052/0 Squamous ...

*List of MeSH codes (C04)

... carcinoma, basosquamous MeSH C04.557.470.200.200 --- carcinoma, ehrlich tumor MeSH C04.557.470.200.220 --- carcinoma, giant ... carcinoma, krebs 2 MeSH C04.557.470.200.260 --- carcinoma, large cell MeSH C04.557.470.200.280 --- carcinoma, lewis lung MeSH ... carcinoma, acinar cell MeSH C04.557.470.200.025.220 --- carcinoma, adenoid cystic MeSH C04.557.470.200.025.232 --- carcinoma, ... carcinoma, medullary MeSH C04.557.465.625.650.240.325 --- carcinoma, merkel cell MeSH C04.557.465.625.650.240.390 --- carcinoma ...

*List of cutaneous conditions

... primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin, trabecular carcinoma of the skin) ... basosquamous cell acanthoma, inflamed seborrheic keratosis) Isthmicoma (infundibuloma, tumor of the follicular infundibulum) ... Microcystic adnexal carcinoma (sclerosing sweat duct carcinoma) Micronodular basal cell carcinoma Milia en plaque Milium Mixed ... Polypoid basal cell carcinoma Pore-like basal cell carcinoma Primary cutaneous adenoid cystic carcinoma Proliferating ...
In the recent years, basaloid squamous cell carcinomas (BSCCs) have gained attention because of (1) observation of a relative increase in the number of tumors arising particularly in head and neck sites, (2) identification of human papillomavirus (HP
Basaloid squamous cell carcinoma (Bas-SqCC) is an uncommon histological variant of lung cancer composed of cells exhibiting cytological and tissue architectural features of both squamous cell lung carcinoma and basal cell carcinoma. Lung cancer is a large and exceptionally heterogeneous family of malignancies. Over 50 different histological variants of lung cancer are explicitly recognized within the fourth (2004) revision of the World Health Organization Classification of Lung Tumours ("WHO-2004"). Many of these entities are quite rare, have only been recently described, and remain poorly understood. Basaloid forms of lung carcinoma were first described in the peer-reviewed medical literature by Dr. Elisabeth Brambilla and her colleagues in 1992. In the third revision of the World Health Organization lung tumor typing and classification scheme, published in 1999, basaloid variants of both squamous cell lung carcinoma (SqCC) and large cell lung carcinoma (LCLC) were recognized as distinct ...
Major diagnostic pitfalls in pulmonary cytology include the differential diagnosis of benign/reactive conditions versus carcinoma and classification of neoplasms. While in the past the distinction between small cell and non-small cell carcinomas was adequate for therapeutic purposes, the new targeted therapies require further classification of non-small cell carcinoma into squamous carcinoma and adenocarcinoma. Improved survival in cancer patients has led to the increased occurrence of second and third primaries, necessitating the use of immunocytochemical stains to determine the primary source. Furthermore, the increasing need for molecular studies mandates prudent use of immunostains in order to conserve tissue. In this session, fine needle aspirates and bronchoscopic specimens from various conditions are presented with an emphasis on the differential diagnosis of reactive bronchial or alveolar cells versus carcinoma, classification of small cell neoplasms (basaloid squamous carcinoma versus ...
Major diagnostic pitfalls in pulmonary cytology include the differential diagnosis of benign/reactive conditions versus carcinoma and classification of neoplasms. While in the past the distinction between small cell and non-small cell carcinomas was adequate for therapeutic purposes, the new targeted therapies require further classification of non-small cell carcinoma into squamous carcinoma and adenocarcinoma. Improved survival in cancer patients has led to the increased occurrence of second and third primaries, necessitating the use of immunocytochemical stains to determine the primary source. Furthermore, the increasing need for molecular studies mandates prudent use of immunostains in order to conserve tissue. In this session, fine needle aspirates and bronchoscopic specimens from various conditions are presented with an emphasis on the differential diagnosis of reactive bronchial or alveolar cells versus carcinoma, classification of small cell neoplasms (basaloid squamous carcinoma versus ...
Study Flashcards On 09/13/07 BSCC2093 Notes Tissue - Epithelia at Cram.com. Quickly memorize the terms, phrases and much more. Cram.com makes it easy to get the grade you want!
Jones, C., Nonni, A. V., Fulford, L., Merrett, S., Chaggar, R., Eusebi, V., Lakhani, S. R. (2001) CGH analysis of ductal carcinoma of the breast with basaloid/myoepithelial cell differentiation. BRITISH JOURNAL OF CANCER, 85 (3). pp. 422-427. ISSN 0007-0920 ...
For patient information click here Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Maneesha Nandimandalam, M.B.B.S.[2] Synonyms and Keywords: Basal cell epithelioma, rodent ulcer, Ronald Reagan tumor, infiltrative basal cell carcinoma, basal-cell cancer,Skin Fibroepithelial Basal Cell Carcinoma, Skin Signet Ring Cell Basal Cell Carcinoma, Skin Sarcomatoid Basal Cell Carcinoma, Superficial Multifocal Basal Cell Carcinoma, Superficial Basal Cell Carcinoma, Skin Basosquamous Cell Carcinoma, Skin Nodular Basal Cell Carcinoma, Skin Morphea-Type (Sclerosing) Basal Cell Carcinoma, Skin Clear Cell Basal Cell Carcinoma, and Skin Adamantinoid Basal Cell Carcinoma ...
Study Flashcards On 09/18/07 BSCC2093 Notes - Glands and Connective Tissue at Cram.com. Quickly memorize the terms, phrases and much more. Cram.com makes it easy to get the grade you want!
Omar, R, Morton, L, Halliday, DA, Danns, E, Beirne, M, Blot, W and Taylor, K (2001) Outlet strut fracture of BSCC valves - The UK Cohort Study. Heart, 86 (1). pp. 57-62. ISSN 1468-201X Full text not available from this repository ...
The basaloid carcinoma is a rare and distinct type of squamous carcinoma. Of all the squamous carcinomas, the basaloid tumor is noted for its high aggressivity and fast replication rate. It is usually discovered within the upper levels of the larynx (supraglottis), the tongue base or the piriform sinuses in male patients ranging from sixty to eighty years old. The aggressivity of the tumor also means its discovery is usually a late event thus associating a relatively low survival rate within the first 5 years. The current paper presents the case of a patient diagnosed with a malign tumor of the larynx which is then identified as being a squamous basaloid carcinoma. The medical review of the patient reveals a long history of smoking and also pulmonary tuberculosis, for which the patient underwent left pneumonectomy.
Cytological, histological, and immunohistochemical findings of pulmonary carcinomas with basaloid features | John P. Crapanzano; Kristina Loukeris; Alain C. Borczuk; Anjali Saqi | download | BookSC. Download books for free. Find books
Histology revealed in the cervical stroma an organoid proliferation of rounded nests of uniform basaloid cells with scanty cytoplasm, peripheral palisading and rare mitotic figures; only focal glandular alcianophilic or squamous differentiation in the central areas of the nests was found. The lesion measured approximately 9x7 mm. Multiple foci of high-grade CIN were observed in the superficial squamous epithelium. The nests of basaloid cells showed intense and diffuse cytoplasmatic p16 immunoreactivity along with strong low molecular weight cytokeratin (8-18) positivity. There was focal and weak positivity for cytokeratin 7, EMA and CD-117, whereas CEA and p53 resulted negative. Proliferative index (Ki-67) was 10 % . In Situ Hybridization for high risk HPV showed positivity in both basaloid nests and CIN ...
Histology revealed in the cervical stroma an organoid proliferation of rounded nests of uniform basaloid cells with scanty cytoplasm, peripheral palisading and rare mitotic figures; only focal glandular alcianophilic or squamous differentiation in the central areas of the nests was found. The lesion measured approximately 9x7 mm. Multiple foci of high-grade CIN were observed in the superficial squamous epithelium. The nests of basaloid cells showed intense and diffuse cytoplasmatic p16 immunoreactivity along with strong low molecular weight cytokeratin (8-18) positivity. There was focal and weak positivity for cytokeratin 7, EMA and CD-117, whereas CEA and p53 resulted negative. Proliferative index (Ki-67) was 10 % . In Situ Hybridization for high risk HPV showed positivity in both basaloid nests and CIN ...
Doctors give unbiased, trusted information on whether Luminal can cause or treat Allergies: Dr. Ajluni on medicine for luminal allergy: Molecular biologists can subtype breast cancers in many ways. One classification looks at luminal (phenobarbital) vs. Basaloid cells of origin. Each has specific molecular biology, but luminal (phenobarbital) types tend to have estrogen receptors and basaloid do not. Er+ tumors fare better. The susan g. Komen website explains this well in lay terms. Http://ww5.komen. Org/breastcancer/subtypesofbreastcancer. Html.
You can fairly be certain that by increasing human growth hormone levels in your body, you will also achieve higher energy levels. This is brought by the hormones actions of increasing resting metabolic rate, sustaining activity levels, and burning necessary body fats for energy conversion. Moreover, human growth hormone also makes it probable to use excessive blood sugar for energy instead of being stored as unnecessary fats in the body.. Improved Athletic Performance. If you are an athletic person or simply an active one, you can benefit a lot by increasing your human growth hormone. Apart from increased energy levels, the hormone seems to be helpful in increasing endurance and recovery time between exercise routines as well. It can bring about improvement of oxygen delivery to different organs in the body. Furthermore, it can help you perform even the most tiresome job you can ever get.. Strengthened Immunity. Fighting away diseases and infections can be very difficult if you have poor ...
Research in Spatial Cognition investigates the acquisition, organization, utilization and revision of information about real and abstract spatial environments by human beings and in technical systems. Examples for such system are mobile robots, but also mobile communication paradigms. The Bremen Spatial Cognition Center (BSCC) is an interdisciplinary research institute at the University of Bremen, Germany. It succeeds the Transregional Collaborative Research Center SFB/TR 8 Spatial Cognition which has been funded by the German Research Foundation (DFG) from 2003-2014.. The BSCC is located in the Cartesium building on campus. Follow us on ...
Punch biopsies from both patients revealed an infiltrating neoplasm with prominent microcystic features that mimick tubuloglandular structures, lined by hyperchromatic basaloid cells, which were strongly positive for chromogranin and BerEP4, variably positive for CK7 and CK5/6 and negative for CK20, synaptophysin, S-100, epithelial membrane antigen (EMA), gross cystic disease fluid protein-15 (GCDFP-15), estrogen/progesterone receptors (ER/PR), thyroid transcription factor 1 (TTF1) and carcinoembryonic antigen (CEA ...
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Natural health care news and research results for complementary and alternative health as well as mainstream medical results. From Canadas Guide to Natural, Herbal, Holistic, and Complementary Healthcare - NaturalHealthcare.ca
TY - JOUR. T1 - Carcinosarcoma in the cecum. AU - Ryu, Youngjoon. AU - Kim, Aeree. AU - Kim, Han Kyeom. AU - Lee, Beomjae. AU - Jung, Woonyong. PY - 2012/7/1. Y1 - 2012/7/1. N2 - Carcinosarcoma of the colon is rare. Seventeen cases have been reported in the English literature. Most cases occurred in the left side of the colon. Indeed, there is only one reported case of cecal carcinosarcoma. Carcinosarcoma has a tendency to distantly metastasize and shows dismal prognosis. We report a case of carcinosarcoma in the cecum and review the literature describing colonic carcinosarcoma.. AB - Carcinosarcoma of the colon is rare. Seventeen cases have been reported in the English literature. Most cases occurred in the left side of the colon. Indeed, there is only one reported case of cecal carcinosarcoma. Carcinosarcoma has a tendency to distantly metastasize and shows dismal prognosis. We report a case of carcinosarcoma in the cecum and review the literature describing colonic carcinosarcoma.. KW - ...
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Discussion:. The overall morphology of this case is typical of a small cell carcinoma, and the immunoprofile supports the diagnosis. The differential diagnosis is listed in question 1. The history of prostatic adenocarcinoma, brain metastases and diffuse lymphadenopathy raise the possibility of metastatic prostatic adenocarcinoma. However the prostate adenocarcinoma typically has prominent nucleoli and acinar-like cell arrangement, which clearly were not seen in this case. The oval shaped nuclei, fine chromatin and nuclear molding are against lymphoma. The small size of tumor cells, lack of prominent nucleoli and lack of abundant cytoplasm are against LCNEC. Distinction from SCC, basaloid type can be difficult based on Diff-Quick and H/E stains only. Positive staining for neuroendocrine markers and lack of history SCC are against poorly differentiated basaloid SCC. The site of origin of metastatic SmCC cannot be determined based on histopathologic or immunophenotypic findings, and requires ...

Syringoma disease: Malacards - Research Articles, Drugs, Genes, Clinical TrialsSyringoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

basosquamous carcinoma 10.5. GFAP VIM 38. mitochondrial myopathy with lactic acidosis 10.5. MUC1 VIM ... Coexistence of Adult Onset Eruptive Syringoma and Bilateral Renal Cell Carcinoma: A Case Report. ( 27922891 ) ... An important mimicker: plaque-type syringoma mistakenly diagnosed as microcystic adnexal carcinoma. ( 25111356 ) ...
more infohttp://www.malacards.org/card/syringoma

Basal cell carcinoma - wikidocBasal cell carcinoma - wikidoc

Skin Basosquamous Cell Carcinoma, Skin Nodular Basal Cell Carcinoma, Skin Morphea-Type (Sclerosing) Basal Cell Carcinoma, Skin ... Skin Fibroepithelial Basal Cell Carcinoma, Skin Signet Ring Cell Basal Cell Carcinoma, Skin Sarcomatoid Basal Cell Carcinoma, ... Differentiating Basal Cell Carcinoma from other Diseases. Epidemiology and Demographics. Risk Factors. Screening. Natural ... Superficial Multifocal Basal Cell Carcinoma, Superficial Basal Cell Carcinoma, ...
more infohttp://www.wikidoc.org/index.php/Basal_cell_carcinoma

Basosquamous carcinoma with systemic metastasis in a miniature...Basosquamous carcinoma with systemic metastasis in a miniature...

Basosquamous carcinoma (BSCC) is a rare malignancy, primarily composed of basal cells ... Basosquamous carcinoma with systemic metastasis in a miniature Pinscher.: ... Basosquamous carcinoma with systemic metastasis in a miniature Pinscher.. Authors * Shin, Sang-Kyung ... Basosquamous carcinoma (BSCC) is a rare malignancy, primarily composed of basal cells with foci of squamous differentiation. It ...
more infohttps://www.mysciencework.com/publication/show/basosquamous-carcinoma-systemic-metastasis-miniature-pinscher-c99c7f72

Philippine EJournals| Basosquamous Carcinoma of the NeckPhilippine EJournals| Basosquamous Carcinoma of the Neck

Basosquamous carcinoma, a variant of basal cell carcinoma, is rather rare with an incidence of only 1 - 2% of cases. 1, 2 It ... Basosquamous carcinoma, a variant of basal cell carcinoma, is rather rare with an incidence of only 1 - 2% of cases. 1, 2 It ... 1 Unlike typical basal cell carcinoma, basosquamous carcinoma behaves more aggressively with a higher tendency for metastasis ... 1 Unlike typical basal cell carcinoma, basosquamous carcinoma behaves more aggressively with a higher tendency for metastasis ...
more infohttps://ejournals.ph/article.php?id=9650

Dr. Virgil Willard II, MD - Reviews - High Point, NCDr. Virgil Willard II, MD - Reviews - High Point, NC

Basosquamous Carcinoma. *Benign Tumor. *Blepharoplasty. *Body Contouring (After Weight Loss Surgery). *Body Disproportion ...
more infohttps://www.healthgrades.com/physician/dr-virgil-willard-ghjsh

October 1986 - Volume 78 - Issue 4 : Plastic and Reconstructive SurgeryOctober 1986 - Volume 78 - Issue 4 : Plastic and Reconstructive Surgery

Basal cell carcinoma of the skin with areas of squamous cell carcinoma: Basosquamous cell carcinoma?. De Faria, J Lopes ... Retrospective Dosak study on carcinomas of the oral cavity. Results and consequences. Platz, H; Fries, R; Hudec, M ... Pathologic findings from the National Surgical Adjuvant Breast Project (protocol 6). I. Intraductal carcinoma (DCIS). Fisher, E ...
more infohttps://journals.lww.com/plasreconsurg/toc/1986/10000

Use of Dermoscopy to Diagnose and Select BCCs that can be Treated Empirically | Springer for Research & DevelopmentUse of Dermoscopy to Diagnose and Select BCCs that can be Treated Empirically | Springer for Research & Development

Purpose of Review The diagnostic value of dermoscopy for basal cell carcinomas (BCCs) is well established. This paper aims to ... Dermoscopy of basosquamous carcinoma. Br J Dermatol. 2013;169(2):358-64.CrossRefPubMedGoogle Scholar ... Basosquamous carcinoma. J Am Acad Dermatol. 2009;60(1):137-43.CrossRefPubMedGoogle Scholar ... Basal cell carcinoma: a dermatopathological and molecular biological update. Br J Dermatol. 2003;148(2):195-202.CrossRefPubMed ...
more infohttps://rd.springer.com/article/10.1007/s13671-018-0215-z

Histopathologic pitfalls of Mohs micrographic surgery and a review of tumor histology | springermedizin.atHistopathologic pitfalls of Mohs micrographic surgery and a review of tumor histology | springermedizin.at

Basosquamous carcinoma. Dermatol Surg. 2003;29(8):830-2, discussion 833. PubMed Bowman PH, Ratz JL, Knoepp TG, Barnes CJ, ... A variant of the squamous cell carcinoma that simulates sebaceous carcinoma. Am J Surg Pathol. 1980;4(6):573-83. PubMedCrossRef ... Eyelid sebaceous carcinoma masquerading as in situ squamous cell carcinoma. Dermatol Surg. 2004;30(2 Pt 1):222-5. PubMed ... Eyelid sebaceous carcinoma masquerading as in situ squamous cell carcinoma. Dermatol Surg. 2004;30(2 Pt 1):222-5. PubMed Lai TF ...
more infohttps://www.springermedizin.at/histopathologic-pitfalls-of-mohs-micrographic-surgery-and-a-revi/14929062

Oro AE[au] - PubMed - NCBIOro AE[au] - PubMed - NCBI

Genetic Mutations Underlying Phenotypic Plasticity in Basosquamous Carcinoma.. Chiang A, Tan CZ, Kuonen F, Hodgkinson LM, ... Mutations in the Kinetochore Gene KNSTRN in Basal Cell Carcinoma.. Jaju PD, Nguyen CB, Mah AM, Atwood SX, Li J, Zia A, Chang ... Efficacy and safety of vismodegib in advanced basal-cell carcinoma.. Sekulic A, Migden MR, Oro AE, Dirix L, Lewis KD, ... Update to an open-label clinical trial of vismodegib as neoadjuvant before surgery for high-risk basal cell carcinoma (BCC). ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Oro+AE%5Bau%5D&dispmax=50

Rieger K[au] - PubMed - NCBIRieger K[au] - PubMed - NCBI

Genetic Mutations Underlying Phenotypic Plasticity in Basosquamous Carcinoma.. Chiang A, Tan CZ, Kuonen F, Hodgkinson LM, ... Incidence ratio of basal cell carcinoma to squamous cell carcinoma equalizes with age. ... Loss of Primary Cilia Drives Switching from Hedgehog to Ras/MAPK Pathway in Resistant Basal Cell Carcinoma. ... Correlates of multiple basal cell carcinoma in a retrospective cohort study: Sex, histologic subtypes, and anatomic ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Rieger+K%5Bau%5D&dispmax=50

Non-melanoma skin cancer - ONANon-melanoma skin cancer - ONA

Basosquamous carcinoma is a tumor that shows histologic features of both SCC and BCC. It generally behaves similarly to a SCC ... Basosquamous carcinoma: Translucent, yellowish papule with telangiectasias.. Figure 26.. Keratoacanthoma: Hyperkeratotic, ... "Basosquamous carcinoma: analysis of prognostic factors influencing recurrence.". Cancer. vol. 88. 2000. pp. 1365-1369. ... "Cutaneous squamous cell carcinoma and other cutaneous carcinomas". AJCC Cancer Staging Manual. Springer SBM, LLC. 2010. pp. 301 ...
more infohttp://www.oncologynurseadvisor.com/oncology/non-melanoma-skin-cancer/article/618748/

Nevus of Ota disease: Malacards - Research Articles, Drugs, Genes, Clinical TrialsNevus of Ota disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

basosquamous carcinoma 9.7. BAP1 BRAF 31. atrophic gastritis 9.7. BRAF TP53 32. arteritic anterior ischemic optic neuropathy ...
more infohttp://www.malacards.org/card/nevus_of_ota

Carcinoma | definition of carcinoma by Medical dictionaryCarcinoma | definition of carcinoma by Medical dictionary

... carcinoma explanation free. What is carcinoma? Meaning of carcinoma medical term. What does carcinoma mean? ... Looking for online definition of carcinoma in the Medical Dictionary? ... basosquamous carcinoma carcinoma that histologically exhibits both basal and squamous elements.. bile duct carcinoma 1. ... Nasopharyngeal carcinoma, bronchogenic carcinoma, Lung carcinoma. carcinoma. [kahr″sĭ-no´mah] (pl. carcinomas, carcino´mata) a ...
more infohttps://medical-dictionary.thefreedictionary.com/carcinoma

Adenocystic carcinoma | definition of adenocystic carcinoma by Medical dictionaryAdenocystic carcinoma | definition of adenocystic carcinoma by Medical dictionary

What is adenocystic carcinoma? Meaning of adenocystic carcinoma medical term. What does adenocystic carcinoma mean? ... Looking for online definition of adenocystic carcinoma in the Medical Dictionary? adenocystic carcinoma explanation free. ... basosquamous carcinoma carcinoma that histologically exhibits both basal and squamous elements.. bile duct carcinoma 1. ... adenocystic carcinoma. Also found in: Dictionary, Thesaurus, Encyclopedia. carcinoma. [kahr″sĭ-no´mah] (pl. carcinomas, carcino ...
more infohttps://medical-dictionary.thefreedictionary.com/adenocystic+carcinoma

NAVER Academic > Search...NAVER Academic > Search...

Cutaneous basosquamous carcinoma. Review of the literature and report of 35 cases.. 1973 D M Borel Archives of Pathology cited ... Adult, Aged, Carcinoma, Basosquamous, pathology, Female, Follow-Up Studies, Humans, Male, Middle Aged, Neoplasm Metastasis, ... Adenocystic carcinomas.. 1973 I Kino et al. Archives of Pathology cited 14 times ... Adult, Aged, Aneuploidy, Carcinoma, Adenoid Cystic, pathology, Cell Nucleus, analysis, DNA, Diploidy, Female, Humans, ...
more infohttps://academic.naver.com/search.naver?field=3&query=Archives+of+Pathology+95%EA%B6%8C+5%ED%98%B8

Topical Aminolevulinic Acid in Patients With Nonmelanoma Skin CancerTopical Aminolevulinic Acid in Patients With Nonmelanoma Skin Cancer

Carcinoma, Basal Cell. *Carcinoma, Basosquamous. *Carcinoma, Squamous Cell. .map{width:100%;height:300px;margin-bottom:15px;} ...
more infohttp://www.knowcancer.com/cancer-trials/NCT00663910/

September 2015 - Volume 26 - Issue 6 : Journal of Craniofacial SurgerySeptember 2015 - Volume 26 - Issue 6 : Journal of Craniofacial Surgery

Basosquamous or Basal Cell Carcinoma? The Importance of the Differential Diagnosis. Terenzi, Valentina; Cassoni, Andrea; Della ... Recurrent Lymphoepithelial Carcinoma of the Parotid Gland. Gökdogan, Ozan; Koybasioglu, Ahmet Gökdogan, Ozan; Koybasioglu, ... Reconstruction With Modified Face Lift and Orbicularis Oculi V-Y Advancement Flap for Sebaceous Carcinoma on Temple Area. Lee, ...
more infohttps://journals.lww.com/jcraniofacialsurgery/Pages/toc.aspx?year=2015&issue=09000

Benign Skin Lesions: Overview, Defining the Lesion, Papules and PlaquesBenign Skin Lesions: Overview, Defining the Lesion, Papules and Plaques

This squamous metaplasia is a consequence of irritation and requires careful discrimination from basosquamous carcinoma. A ... This squamous metaplasia is a consequence of irritation and requires careful discrimination from basosquamous carcinoma. A ... The carcinomas associated with Muir-Torre syndrome have a more favorable prognosis than nonsyndromic carcinomas. ... The carcinomas associated with Muir-Torre syndrome have a more favorable prognosis than nonsyndromic carcinomas. ...
more infohttps://emedicine.medscape.com/article/1294801-overview

Basal cell carcinoma: 10-year experience with electrochemotherapy | Journal of Translational Medicine | Full TextBasal cell carcinoma: 10-year experience with electrochemotherapy | Journal of Translational Medicine | Full Text

... that ECT stands out as a safe and well-tolerated alternative treatment for patients with multiple or large basal cell carcinoma ... The pathology report indicated a metastasis from basosquamous carcinoma. The patient received anti-hedgehog therapy (vismodegib ... Basal cell carcinoma epidemiology in the UK: the elephant in the room. Clin Exp Dermatol. 2013;38(4):367-9.PubMedView Article ... Rubin AI, Chen EH, Ratner D. Basal-cell carcinoma. New Engl J Med. 2005;353(21):2262-9.PubMedView ArticleGoogle Scholar. ...
more infohttps://translational-medicine.biomedcentral.com/articles/10.1186/s12967-017-1225-5

Non-melanoma skin cancerNon-melanoma skin cancer

Basosquamous carcinoma (. Figure 25. ) Figure 25.. Basosquamous carcinoma: Translucent, yellowish papule with telangiectasias. ... Basosquamous carcinoma is a tumor that shows histologic features of both SCC and BCC. It generally behaves similarly to a SCC ... Non-melanoma skin cancer (basal cell carcinoma and squamous cell carcinoma) * What every physician needs to know: * Basal cell ... Basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (SCC) comprise the vast majority of non-melanoma skin cancers ...
more infohttps://www.endocrinologyadvisor.com/oncology/non-melanoma-skin-cancer/article/618750/

Anti-SLC12A2 Antibodies | Invitrogen
                                                
                    
                    ...Anti-SLC12A2 Antibodies | Invitrogen ...

Diseases associated with SLC12A2 include Basosquamous Carcinoma and Metatypical Basal Cell Carcinoma. ...
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NKCC1 Antibody (PA5-69256)
                
                
		        
	NKCC1 Antibody (PA5-69256)

Diseases associated with SLC12A2 include Basosquamous Carcinoma and Metatypical Basal Cell Carcinoma. ...
more infohttps://www.thermofisher.com/antibody/product/NKCC1-Antibody-Polyclonal/PA5-69256

Publications - Mayo ClinicPublications - Mayo Clinic

Basosquamous carcinoma and metatypical basal cell carcinoma: a review of treatment with Mohs micrographic surgery. Int J ... Multiple squamous cell carcinomas in the setting of psoriasis treated with etanercept: a report of four cases and review of the ... Primary mucinous carcinoma of the skin: the Mayo Clinic experience over the past 2 decades. Dermatol Surg. 2015 Feb; 41(2):201- ... Merkel cell carcinoma in the setting of chronic lymphocytic leukemia. Dermatol Surg. 2011 Aug; 37(8):1100-5. Epub 2011 Jun 01. ...
more infohttp://www.mayo.edu/research/searchpublications/publications?authid=14276402

TDMS Study 88007-05 Pathology TablesTDMS Study 88007-05 Pathology Tables

Squamous Cell Carcinoma, Basal Cell Carcinoma, Basosquamous , , Tumor (malignant or NOS), or Carcinoma ... Cell Carcinoma, Carcinoma, Basosq. Tumor , , (M or B), Basal Cell Adenoma, Adenoma, Papilloma, Sq Papilloma, Keratoacanthoma, ... Basal Cell Carcinoma, Basal Cell Adenoma, Basosquamous , , Tumor (benign, malignant or NOS), or Trichoepithelioma ... Carcinoma or Adenoma Mammary Gland Fibroadenoma Fibroma, Fibroadenoma, Carcinoma, or Adenoma All Organs Leukemia: Lymphocytic, ...
more infohttps://ntp.niehs.nih.gov/data/tables/unorgpath/8xxxx/88007/05p08/index.html
  • Griffiths RW, Suvarna SK, Stone J. Do basal cell carcinomas recur after complete conventional surgical excision? (springer.com)