Carcinoma, Squamous Cell
A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
Plutonium. A naturally radioactive element of the actinide metals series. It has the atomic symbol Pu, atomic number 94, and atomic weight 242. Plutonium is used as a nuclear fuel, to produce radioisotopes for research, in radionuclide batteries for pacemakers, and as the agent of fission in nuclear weapons.
Carcinoma in Situ
Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
Tumor Markers, Biological
Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.
A family of small, non-enveloped DNA viruses infecting birds and most mammals, especially humans. They are grouped into multiple genera, but the viruses are highly host-species specific and tissue-restricted. They are commonly divided into hundreds of papillomavirus "types", each with specific gene function and gene control regions, despite sequence homology. Human papillomaviruses are found in the genera ALPHAPAPILLOMAVIRUS; BETAPAPILLOMAVIRUS; GAMMAPAPILLOMAVIRUS; and MUPAPILLOMAVIRUS.
Carcinoma, Ductal, Breast
A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.
Carcinoma, Basal Cell
A malignant skin neoplasm that seldom metastasizes but has potentialities for local invasion and destruction. Clinically it is divided into types: nodular, cicatricial, morphaic, and erythematoid (pagetoid). They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck area and the remaining 15% on the trunk and limbs. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1471)
Carcinoma, Non-Small-Cell Lung
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Receptor, Epidermal Growth Factor
A cell surface receptor involved in regulation of cell growth and differentiation. It is specific for EPIDERMAL GROWTH FACTOR and EGF-related peptides including TRANSFORMING GROWTH FACTOR ALPHA; AMPHIREGULIN; and HEPARIN-BINDING EGF-LIKE GROWTH FACTOR. The binding of ligand to the receptor causes activation of its intrinsic tyrosine kinase activity and rapid internalization of the receptor-ligand complex into the cell.
Carcinoma, Transitional Cell
Human papillomavirus DNA in adenosquamous carcinoma of the lung. (1/236)AIM: To investigate the presence of human papillomavirus (HPV) DNA in adenosquamous carcinoma of the lung--which is relatively common in Okinawa but not in mainland Japan--and examine its histological features. METHODS: Of 207 cases where primary lung cancers were surgically removed between January 1995 and June 1997 in Okinawa, 23 were adenosquamous carcinoma. HPV was detected by non-isotopic in situ hybridisation (NISH) and polymerase chain reaction (PCR) amplification with primers specific for E6 and E7 regions of the HPV genome. PCR products were analysed by Southern blotting. Immunohistochemical determination of high molecular weight cytokeratin (HMC) and involucrin was also carried out. RESULTS: 18 cases were positive for HPV DNA by PCR and NISH. HPV types 6, 11, 16, and 18 were found. Seven cases were dual positive for different types of HPV. Using NISH, HPV was also found in the squamous cell components and in neighbouring enlarged adenocarcinoma cells. The HMC and involucrin were demonstrated immunohistochemically in the same areas. CONCLUSIONS: HPV DNA was found in a high proportion (78.3%) of adenosquamous carcinomas in Okinawa, a region where HPV has previously been shown to be prevalent in squamous cell carcinoma of the lung. The adenocarcinoma cells adjacent to the squamous cell carcinoma component were enlarged and positive for HPV, HMC, and involucrin. This is thought to indicate the transition from adenocarcinoma to squamous cell carcinoma. (+info)
Randomized comparison of fluorouracil plus cisplatin versus hydroxyurea as an adjunct to radiation therapy in stage IIB-IVA carcinoma of the cervix with negative para-aortic lymph nodes: a Gynecologic Oncology Group and Southwest Oncology Group study. (2/236)PURPOSE: In 1986, a protocol comparing primary radiation therapy (RT) plus hydroxyurea (HU) to irradiation plus fluorouracil (5-FU) and cisplatin (CF) was activated by the Gynecologic Oncology Group (GOG) for the treatment of patients with locally advanced cervical carcinoma. The goals were to determine the superior chemoradiation regimen and to quantitate the relative toxicities. METHODS: All patients had biopsy-proven invasive squamous cell carcinoma, adenocarcinoma, or adenosquamous carcinoma of the uterine cervix. Patients underwent standard clinical staging studies and their tumors were found to be International Federation of Gynaecology and Obstetrics stages IIB, III, or IVA. Negative cytologic washings and para-aortic lymph nodes were required for entry. Patients were randomized to receive either standard whole pelvic RT with concurrent 5-FU infusion and bolus CF or the same RT plus oral HU. RESULTS: Of 388 randomized patients, 368 were eligible; 177 were randomized to CF and 191 to HU. Adverse effects were predominantly hematologic or gastrointestinal in both regimens. Severe or life-threatening leukopenia was more common in the HU group (24%) than in the CF group (4%). The difference in progression-free survival (PFS) was statistically significant in favor of the CF group (P = .033). The sites of progression in the two treatment groups were not substantially different. Survival was significantly better for the patients randomized to CF (P = .018). CONCLUSION: This study demonstrates that for patients with locally advanced carcinoma of the cervix, the combination of 5-FU and CF with RT offers patients better PFS and overall survival than HU, and with manageable toxicity. (+info)
Haematogenous cytokeratin 20 mRNA as a predictive marker for recurrence in oral cancer patients. (3/236)We examined the expression of cytokeratin 20 (CK20) mRNA in the peripheral blood of oral squamous cell carcinoma (SCC) patients by reverse transcriptase polymerase chain reaction (RT-PCR). Eleven out of 12 oral SCC patients showed positive RT-PCR results. However, there is no clear relationship between the haematogenous CK20 mRNA and the metastasis. After initial treatment, all of the tumour-free survivors tested showed negative RT-PCR results. CK20 mRNA in peripheral blood can be used as a marker for tumour recurrence but not not for metastasis in oral SCC patients. (+info)
A population-based survey of the management of women with cancer of the cervix. (4/236)The aim of this study was to investigate the influence of diagnostic throughput on survival outcome for women with cancer of the cervix. We conducted a case note review of 359 women in Lancashire and Greater Manchester diagnosed with cancer of the cervix during 1990, identified from records held by the North Western Regional Cancer Registry. Univariate and multivariate survival analyses were undertaken to investigate the influence on survival of woman, disease and treatment related factors. Following adjustment for woman- and disease-related factors there was no evidence of a statistically significant association between diagnostic throughput and survival. The findings of this study do not support the need for any change in the referral patterns to gynaecologists of women with symptoms suggestive of cancer of the cervix. (+info)
Overexpression of cyclooxygenase-2 in carcinoma of the pancreas. (5/236)The level of cyclooxygenase (COX)-2 has been investigated recently in various human carcinomas. In the present study, we examined the distribution and extent of COX-2 protein in human pancreatic tumors using immunohistochemistry. A strong expression of COX-2 protein was present in 23 of 52 (44%) pancreatic carcinomas, a moderate expression was present in 24 of 52 (46%) pancreatic carcinomas, and a weak expression was present in 5 of 52 (10%) pancreatic carcinomas. In contrast, benign tumors showed weak expression or no expression of COX-2, and only islet cells displayed COX-2 expression in normal pancreatic tissues. Overexpression of COX-2 in carcinoma tissues was also confirmed by Western blot analysis. Furthermore, consistent with the results at protein levels, reverse transcription-PCR analyses indicated that COX-2 mRNA was overexpressed in 7 of 13 (54%) carcinomas, but in none of 3 benign tumors. Our findings suggest that COX-2 inhibitors might be potentially effective against pancreatic carcinomas and that COX-2 may be involved in certain biological processes in pancreatic islets. (+info)
Adenosquamous carcinoma of the prostate. (6/236)An unusual adenosquamous carcinoma originating in the prostate of a 73-year-old man is described. The histological finding showed a well differentiated squamous cell carcinoma admixed in an adenocarcinomatous area. A transitional area of 2 carcinomatous elements was also noted. Seven months prior to the development of this lesion, a diagnosis of adenocarcinoma had been established by transurethral resection of the prostate and the patient had been treated with bilateral orchiectomy. This is the first case of adenosquamous carcinoma of the prostate reported in Korea. The pathogenesis and previous reports of this lesion will be discussed. (+info)
Carbonic anhydrase IX antigen differentiates between preneoplastic malignant lesions in non-small cell lung carcinoma. (7/236)The MaTu interval (MN)/carbonic anhydrase (CA) IX tumour-associated antigen is a protein that is normally expressed in the gut and belongs to the carbonic anhydrase enzyme family (CA IX). It has been detected in tumour cell lines and in some solid tumours including cervical, oesophageal and clear cell renal carcinoma. This study determined MN/CA IX expression in 65 primary non-small cell lung cancer resected with curative intent and in 38 bronchial preneoplastic lesions, carcinoma in situ or microinvasive carcinoma as well as in normal bronchial tissue. The presence of MN/CA IX was detected using immunohistochemistry and Western blot analysis, whenever frozen material was available. Immunostaining was positive in 52/65 (80%) of the tumour samples. The staining was more often focal than diffuse. The percentage of stained cells in positive tumours was highly variable, ranging 1-85%. The pattern of immunostaining was predominantly cytoplasmic with a membranous reinforcement (87%). The intensity was mainly strong (69%). The presence of the protein in the tumour was confirmed by Western blot analysis in the eight samples tested. All the morphologically normal epithelia, except in close vicinity of tumours in some cases, as well as the preneoplastic bronchial lesions (basal cell hyperplasia, metaplasia and dysplasia) were immunonegative for MN/CA IX expression. In contrast, carcinoma in situ and microinvasive epithelioma showed the presence of MN-immunopositive tumoural cells in 5/7 and 4/5 of the samples, respectively. These data suggest that MN/CA IX is a useful marker for the differentiation between preneoplastic lesions and bronchial non-small cell lung cancer in the lung. (+info)
Inhibitory effects of combined administration of antibiotics and anti-inflammatory drugs on lung tumor development initiated by N-nitrosobis(2-hydroxypropyl)amine in rats. (8/236)The effects of antibiotics and anti-inflammatory drugs on the promotion stage of lung carcinogenesis initiated with N-nitrosobis(2-hydroxypropyl)amine (BHP) in rats were investigated in two experiments with a similar protocol. In experiment 1, rats received tap water containing 2000 p.p.m. BHP for 12 weeks followed by basal diet or basal diet containing 0.02% erythromycin (EM), 0. 04% ampicillin (ABPC), 1.5% sho-saiko-to, 0.02% EM plus 1.5% sho-saiko-to or 0.04% ABPC plus 1.5% sho-saiko-to for 8 weeks after BHP administration. The development of adenocarcinomas (AC), squamous cell carcinomas (SqC) and adenosquamous carcinomas (ASqC) was completely inhibited in rats given ABPC plus sho-saiko-to and the numbers of lung lesions including alveolar hyperplasias, adenomas and carcinomas were decreased in rats given EM plus sho-saiko-to or ABPC plus sho-saiko-to. Neutrophil and macrophage infiltration into alveolar spaces of the lung were also markedly suppressed. In experiment 2, rats received BHP in the same manner as in experiment 1 and basal diet or basal diet containing 0.04% ABPC, 0.006% piroxicam, 0.04% ABPC plus 0.006% piroxicam and 0.04% ABPC plus 0.75% ougon for 8 weeks. The incidence and number of carcinomas, including ACs, SqCs and ASqCs were decreased in rats given ABPC plus piroxicam or ABPC plus ougon. Bacteria, mainly Escherichia coli, were detected in broncho-alveolar lavage of rats receiving BHP. The results suggest that chronic inflammation might be involved in the progression of lung carcinogenesis by BHP in rats and its suppression may therefore be useful as a chemopreventive strategy in lung cancer clinics. (+info)
Poor prognosis in patients with adenosquamous cell carcinoma of the cervix
From 1 July 1974 to 31 December 1982, 127 patients with primary carcinoma of the cervix were assessed to determine the prognosis of patients with adenosquamous cell carcinoma. Of all patients, 34 are dead of disease for an overall corrected survival rate of 73.2%. The survival of 20 patients with adenosquamous cell carcinoma is 20%. Seventy-five percent of the adenosquamous cell patients had stage IB lesions. When patients with adenosquamous cell carcinoma were compared with patients with squamous cell carcinoma or adenocarcinoma, there was a statistically significant decrease in survival. Patients with adenosquamous cell carcinoma were relatively young with a mean age of 41.1 years. A normal appearing cervix was noted in 30% of all patients with adenosquamous cell carcinoma. The majority of adenosquamous cell patients (87.5%) dead from cancer had distant metastases. This report emphasizes that, independent of stage, adenosquamous cell cervical carcinoma is an extremely aggressive neoplasm and ...
Clinical features and outcomes of 25 patients with primary adenosquamous cell carcinoma of the prostate - Open Access Library
The aim of the present study was to examine the epidemiology, natural history, treatment and long-term survival of patients with adenosquamous cell carcinoma of the prostate. The Surveillance, Epidemiology, and End Results (SEER) Program database was used ...
Human Papillomavirus Types and Localization in Adenocarcinoma and Adenosquamous Carcinoma of the Uterine Cervix: A Study by in...
Formalin-fixed, paraffin-embedded tissues from 108 cases of invasive carcinoma of the uterine cervix, consisting of 40 cases of adenocarcinoma, 44 cases of adenosquamous carcinoma, and, as a control, 24 cases of squamous cell carcinoma were examined for the presence of human papillomavirus (HPV) DNA by in situ hybridization of high sensitivity using tritium-labeled HPV-2, HPV-6, HPV-16, and HPV-18 DNA probes. This method detects five genome copies of homologous HPV DNA per cell. HPV DNA was detected with mixed HPV DNA probes in 17 cases (42.5%) of adenocarcinoma, 16 cases (36.4%) of adenosquamous carcinoma, and in 13 cases (54.2%) of squamous cell carcinoma. The types of HPV DNA in the HPV-positive tissues were also analyzed with each individual probe under high stringency conditions. HPV-18 DNA was detected in all but one case of the HPV DNA-positive adenocarcinoma and one-half of the HPV DNA-positive adenosquamous carcinoma. HPV-16 DNA was detected in one case of the HPV DNA-positive ...
LIVER ADENOSQUAMOUS CARCINOMA INVADING THE ESOPHAGOGASTRIC JUNCTION - A CASE-REPORT AND A REVIEW OF THE LITERATURE
A case of adenosquamous carcinoma of the liver involving the esophago-gastric junction is reported. The preoperative diagnosis of a submucosal tumor of the cardia of the stomach was made following a barium meal study, gastrofiberscopy, ultrasonography, and computed tomography. At surgery, a tumor was found measuring 6x5 cm in diameter and involving the left lobe of the liver, lower esophagus and cardia of the stomach, and the origin of the tumor was unclear. Post-operative histopathology revealed that the tumor contained two different malignant components of glandular and squamous cells. An adenosquamous carcinoma originating in the liver was suspected, since the cancer cells did not involve the esophago-gastric mucosa and were mainly located in the S2 of the liver. Despite aggressive adjuvant chemotherapy, the patient died of a recurrence in the liver seven months later. This seems to be the first documentation of adenosquamous carcinoma of the liver invading the esophago-gastric junction ...
A case of adenosquamous carcinoma of lower extrahepatic bile duct<...
TY - JOUR. T1 - A case of adenosquamous carcinoma of lower extrahepatic bile duct. AU - Aoki, Hideki. AU - Kanazawa, Takashi. AU - Fujiwara, Yuko. AU - Morihiro, Toshiaki. AU - Takehara, Kiyoto. AU - Seita, Masayuki. AU - Ohara, Toshiaki. AU - Arata, Takashi. AU - Nakagawa, Hitoshi. AU - Tanakaya, Koji. AU - Takeuchi, Hitoshi. N1 - Copyright: Copyright 2012 Elsevier B.V., All rights reserved.. PY - 2012/1/15. Y1 - 2012/1/15. N2 - We report a 83-year-old female with bile duct cancer who underwent subtotal stomach preserving pancreatoduodenectomy. Pathologically, her tumor was diagnosed as adenosquamous carcinoma of the lower extrahepatic bile duct with final stage IVb [pT3pN3M (-)]. The prognosis of patients with adenosquamous carcinoma of the bile duct is very poor, and the reason is thought to be its tendency to invade the pancreas. Although she was an aged patient, we performed adjuvant chemotherapy using gemcitabine. No recurrence has occurred until this day, 30 months after the operation. ...
Clinical Significance of Detecting Somatic Gene Mutations in Surgically Resected Adenosquamous Cell Carcinoma of the Lung in...
TY - JOUR. T1 - Clinical Significance of Detecting Somatic Gene Mutations in Surgically Resected Adenosquamous Cell Carcinoma of the Lung in Japanese Patients. AU - Morodomi, Yosuke. AU - Okamoto, Tatsuro. AU - Takenoyama, Mitsuhiro. AU - Takada, Kazuki. AU - Katsura, Masakazu. AU - Suzuki, Yuzo. AU - Fujishita, Takatoshi. AU - Kitahara, Hirokazu. AU - Shimamatsu, Shinichiro. AU - Kohno, Mikihiro. AU - Tagawa, Tetsuzo. AU - Okano, Shinji. AU - Taguchi, Kenichi. AU - Ichinose, Yukito. AU - Maehara, Yoshihiko. PY - 2015/8/1. Y1 - 2015/8/1. N2 - Background: Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) and echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK) inhibitors are effective and useful agents for treating patients who harbor EGFR-TKI-sensitive mutations or EML4-ALK rearrangement. Therefore, the importance of determining the presence of these somatic mutations when treating lung adenocarcinomas is widely accepted. However, genetic ...
Cervix (Human) Tissue Lysate � Adenosquamous Cell Carcinoma � T4-014
Human Cervix Adenosquamous Cell Carcinoma, Grade 2, Stage II, Female, Age 40 Tumor/normal adjacent tissue lysate set, 100 �g each, $270. 1.800.475.1955
Clinical features and outcomes of 25 patients with primary adenosquamous cell carcinoma of the prostate
PubMed Central Canada (PMC Canada) provides free access to a stable and permanent online digital archive of full-text, peer-reviewed health and life sciences research publications. It builds on PubMed Central (PMC), the U.S. National Institutes of Health (NIH) free digital archive of biomedical and life sciences journal literature and is a member of the broader PMC International (PMCI) network of e-repositories.
Background/Purpose: Its been reported previously in situations of adenosquamous carcinoma from - ALK inhibitors are an...
Background/Purpose: Its been reported previously in situations of adenosquamous carcinoma from the lung in Okinawa, a subtropical isle 2000 km of mainland Japan south, the fact that squamous cell carcinoma elements were positive for individual papillomavirus (HPV) by non-isotopic in situ hybridisation (NISH). type 16 (HPV-16) was transfected into cultured colonic adenocarcinoma (DLD-1) and lung adenocarcinoma (Computer-14) cells using the calcium mineral phosphate technique. Neomycin was utilized as a range marker. The current presence of HPV E1, E2, E4, E5, E6, E7, L1, and L2 mRNAs and transglutaminase 1 also, involucrin, cyclin reliant kinases (CDKs), cyclins, caspases, apoptosis inducing aspect, DNase , Fas, and Fas ligand mRNAs in HPV transfected cells was looked into through invert transcription polymerase string response (RT-PCR). The G0CG1 cell inhabitants was analysed by movement cytometry. Morphological examination in light and electron microscopes was completed also. Outcomes: The ...
Adenosquamous carcinoma lung - What Does the Doctor Say?
Helpful, trusted answers from doctors: Dr. Holzman on adenosquamous carcinoma lung: There could be genetic component to a squamous cell cancer, although the exact implications on treatment arent known. Obviously if there is a strong family history of cancers, or if it strikes someone who is young and/or a non smoker/drinker i would suspect a strong genetic contribution. Without more details, it is hard to say with any certainty.
NCT00673049 | Large Cell Carcinoma, Non-Small-Cell Lung Carcinoma, Squamous Cell Carcinoma, Adenosquamous Cell Carcinoma...
This study was terminated on March 8, 2010 due to an analysis by an independent Data Safety Monitoring Committee (DSMC) indicating that the addition of CP-751,871 [figitumumab] to erlotinib [Tarceva] would be unlikely to meet the primary endpoint of improving overall survival when compared to erlotinib alone.. This Oncology study continues as terminated, however for ethical reasons some patients, noted with resultant benefit, continue receiving treatment. ...
adenosquamous cell carcinoma of cervix uteri 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
Grant] United States / NCI NIH HHS / CA / CA 12213; United States / NCI NIH HHS / CA / CA 12644; United States / NCI NIH HHS / CA / CA 13612; United States / NCI NIH HHS / CA / CA 22433; United States / NCI NIH HHS / CA / CA 32102; United States / NCI NIH HHS / CA / CA 35090; United States / NCI NIH HHS / CA / CA 35178; United States / NCI NIH HHS / CA / CA 35192; United States / NCI NIH HHS / CA / CA 35262; United States / NCI NIH HHS / CA / CA 35431; United States / NCI NIH HHS / CA / CA 38926; United States / NCI NIH HHS / CA / CA 42777; United States / NCI NIH HHS / CA / CA 45450; United States / NCI NIH HHS / CA / CA 45461; United States / NCI NIH HHS / CA / CA 46136; United States / NCI NIH HHS / CA / CA 46441; United States / NCI NIH HHS / CA / CA 52654; United States / NCI NIH HHS / CA / CA 58861; United States / NCI NIH HHS / CA / CA 76132; United States / NCI NIH HHS / CA / CA ...
Frequent Loss of Tumor Suppressor ARID1A Protein Expression in Adenocarcinomas/Adenosquamous Carcinomas of the Uterine Cervix |...
If patients could recognise themselves, or anyone else could recognise a patient from your description, please obtain the patients written consent to publication and send them to the editorial office before submitting your response [Patient consent forms] ...
Gallbladder Adenosquamous Carcinoma | Semantic Scholar
A carcinoma that arises from the gallbladder. It is characterized by the presence of glandular and squamous malignant epithelial components.
Mutations of epidermal growth factor receptor and K-ras genes in adenosquamous carcinoma of the lung. - PubMed - NCBI
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
EGFR and KRAS mutations in Chinese patients with adenosquamous carcinoma of the lung. - PubMed - NCBI
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
BC embraces less-invasive breast biopsy system
Low-Grade Adenosquamous Carcinoma of the Breast Developing Around a Localization Wire Fragment. Handa, Priyanka; Khader, Samer N.; Buchbinder, Shalom S.; Guelfguat, Mark // Laboratory Medicine;Summer2015, Vol. 46 Issue 3, p241 We present the case of a 67-year-old white woman with a history of benign biopsy results in the previous 10 years before she developed low-grade adenosquamous carcinoma around a residual localization wire fragment. A possible theory of carcinogenesis may be related to reparative epithelium in a... ...
Salivary glands - Adenosquamous carcinoma
This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patients clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician ...
Immunohistochemical Staining with DeltaNp63 Is Useful for Distinguishing the Squamous Cell Component of Adenosquamous Cell...
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Efficacy of immunohistochemical staining in differentiating a squamous cell carcinoma in poorly differentiated rectal cancer:...
TY - JOUR. T1 - Efficacy of immunohistochemical staining in differentiating a squamous cell carcinoma in poorly differentiated rectal cancer. T2 - Two case reports. AU - Rami, Sairafi. AU - Han, Yoon Dae. AU - Jang, Mi. AU - Cho, Min Soo. AU - Hur, Hyuk. AU - Min, Byung Soh. AU - Lee, Kang Young. AU - Kim, Nam Kyu. PY - 2016/8. Y1 - 2016/8. N2 - A rectal carcinoma, including primary an adenosquamous and a squamous cell carcinoma (SCC), is a very rare disease, accounting for 0.025% to 0.20% of all large-bowel malignant tumors. Because SCCs have a higher mortality than adenosquamous carcinomas, determining whether the primary rectal cancer exhibits an adenomatous component or a squamous component is important. While differentiating between these 2 components, especially in poorly differentiated rectal cancer, is difficult, specific immunohistochemical stains enable accurate diagnoses. Here, we report the use of immunohistochemical stains to distinguish between the adenomatous and the squamous ...
Histological classification of nasopharyngeal carcinoma which - Cancer Health Center
Histological classification of nasopharyngeal carcinoma 6. Adenocarcinoma is extremely rare. Nasopharyngeal mucosa from the small salivary glands or the cancer cells showed a glandular differentiation, with a clear glandular structures. Still shows a small number of bi-directional differentiation of adenosquamous carcinoma. According to the degree of differentiation of cancer cells can be divided into high, medium and poorly differentiated adenocarcinoma. ...
Adeno carcinoma anal cancer | Cancer Survivors Network
Im over here from gyn boards but wanted to throw my two cents in on the adeno subject. HPV can cause cancer in the cells of squamous or the glandular adenocarcinoma. I have adenosquamous carcinoma of the cervix, a rare form of cervical cancer but none the less, hpv associated cervical cancer. Most anal cancers are also hpv related. The probable reason for the more drastic surgical approach is because theadenocarcinomas tend to behave more aggressively than the squamous, and are more resistant to chemo and radiation. They require a more aggressive treatment plan to eliminate and control. I had a radical hysterectomy, chemo, chemo/rads and more chemo and still had a recurrence in the lung two months after completing treatment. I was originally staged at 2a. Had more surgery and chemo and am now NED. I would support the surgery to remove the cancer. We are strong and we adapt. I am 34 with three kids under the age of10 and will do whatever I have to to stick around for them. Good luck to you and ...
DMOZ - Health: Conditions and Diseases: Cancer: Lung: Non-Small Cell
One of two basic types of lung cancer. Non-small cell tumors grow slowly but are less likely to respond to chemotherapy. There are different subtypes of non-small cell lung cancer: adenocarcioma, squamous cell carcinoma, adenosquamous carcinoma, larger cell carcinoma, and undifferentiated carcinoma.
ESMO E-Learning: Important Pathways to Target in (Advanced) NSCLC - A Focus on ALK Inhibition in Non-Small-Cell Lung Cancer ...
Anaplastic lymphoma kinase (ALK) is positive in 2-5% of patients with non-small cell lung cancer (NSCLC). At least 28 different EML4-ALK variants have been identified in NSCLC, but clinical significance of each variant is unknown. Patients with ALK-positive disease tend to be younger, never-light smokers, presenting with adenocarcinoma, adenosquamous carcinoma, and rarely squamous cell carcinoma (SCC). Pleural and pericardial effusion and brain metastases are more common among patients with ALK-positive tumours.. ALK testing should be carried out simultaneously with EGFR at diagnosis of advanced NSCLC. ALK mutation testing is recommended in all patients with advanced NSCLC of a non-squamous subtype regardless of smoking history. Testing is not recommended in patients with an unequivocal diagnosis of SCC, except in never/former light smokers. This E-Learning module elaborates clinical characteristics in patients with ALK-positive NSCLC and provides evidence from clinical studies with ALK ...
Pulmonary Pathology Society
In the world of precision medicine with advances in immunotherapy, accurate histologic classification of lung cancer is more relevant than before due to the prognostic impact and availability of targeted therapy. Adenosquamous carcinoma is composed of both adenocarcinoma and squamous cell carcinoma, with each component constituting at least 10% of the tumor. It accounts for ,4% of all lung cancers, shows a male predominance with median age similar to other lung cancers. It behaves aggressively compared to other non-small cell lung carcinomas. Immunophenotype should support the dual population of tumor cells with distinct components of TTF-1 (&/or Napsin-A) and p40 (&/or p63, CK5/6) positive tumor cells. Entrapped bronchioles with squamous metaplasia and pneumocytes are p40 and TTF-1 positive and may sometimes mimic squamous cell carcinoma and adenocarcinoma respectively. Hence, careful morphologic evaluation to exclude the mimics along with diffuse sheet-like labelling of the immunostains are ...
Clinical Significance of ras Oncogene Activation in Human Lung Cancer | Cancer Research
Activation of ras oncogenes is commonly found in human neoplasms. We have investigated 280 human lung cancer specimens for ras activation, including 38 that have not been reported previously, using an oligonucleotide detection assay. From a total of 141 adenocarcinoma samples from smokers, 41 tested positive for a point mutation in codon 12 of K-ras (30%), while three tumors had another type of ras activation. Only two of 40 cases from nonsmokers had a K-ras mutation (5%), suggesting that K-ras mutations may be directly caused by exposure to carcinogens in tobacco smoke. The majority of the point mutations in adenocarcinomas were guanine to thymine transversions in codon 12 of the K-ras oncogene. Occasional point mutations in ras oncogenes were detected in adenosquamous carcinomas (one of five cases) and large cell carcinoma (one of 24 cases), but no ras activations were found in small cell carcinomas (six cases), squamous carcinomas (48 cases), carcinoid carcinomas (15 cases), or thymoma (one ...
Lirias: Papillomavirus infections
Papillomas or warts are easily recognized skin or mucous membrane tumors. They are common in wild species and are particularly well known in deer (Cosgrove and Fay 1981; Sundberg and Nielson 1981). Most of these tumors are caused by papillomaviruses (PVs). Tumors can become quite large and numerous and persist for prolonged periods, but they usually regress, providing the individual with long-term immunity to future infections. Occasionally, the tumors will progress to squamous cell carcinoma, adenosquamous carcinoma, or sebaceous carcinoma that will eventually kill the host if not treated. Specific mucosotropic PV types and those infecting immunodeficient individuals are prone to induce malignancies. Virtually all mammalian species are hosts for one of more PV. This chapter provides an overview of PV infections in mammals ...
Genevisible - Top 10 cancers for NM 000370
Top 10 cancers for NM_000370 (Homo sapiens, RefSeq): liver, dysplastic nodule, liver, unspecified, liver, hepatocellular carcinoma, NOS, liver cell carcinoma, liver and intrahepatic bile ducts, liver, hepatoblastoma, NOS, sigmoid colon, tubular adenoma, NOS, liver, hepatocellular carcinoma, NOS,metastatic, PDX/CDX, bronchus or lung, adenosquamous carcinoma, PDX/CDX, sigmoid colon, adenoma, NOS
Gene Mutation Found for Aggressive Form of Pancreatic Cancer
Researchers at the University of California, San Diego School of Medicine have identified a mutated gene common to adenosquamous carcinoma (ASC) tumors - the first known unique molecular signature for this rare, but particularly virulent, form of pancreatic cancer.
CiNii 論文 - Adenosquamous carcinoma of the gall-bladder with gastric foveolar-type epithelium ...
真木 健裕 , 原 敬志 , 平野 聡 , 田中 栄一 , 斉藤 克憲 , 竹内 幹也 , 七戸 俊明 , 佐藤 幸作 , 三品 壽雄 , 近藤 哲 日本消化器外科学会雑誌 40(11), 1811-1815, 2007-11-01 CiNii PDF - オープンアクセス 医中誌Web 参考文献19件 被引用文献2件 ...
Papanicolaou check The World Wellness Firm WHO) classifies malignant tumors from the uterine cervix into three classes:...
Background: Adenoid cystic carcinoma (ACC) and adenoid basal carcinoma (ABC) are uncommon in the uterine cervix. .001). Conclusions: Even though the nuclei of both these buy 253863-00-2 tumor types had been oval formed, inferred through the ratio of small axis to main axis (0.728 in ACC and 0.669 in ABC), the region of nuclei was 1 approximately.7 times bigger in ACC than in ABC. Distinguishing nucleic features, including region, morphology, and chromatin design, may be useful in making the correct analysis. Keywords: Adenoid cystic carcinoma, Adenoid basal carcinoma, Genital smears, Papanicolaou check The World Wellness Firm (WHO) classifies malignant tumors from the uterine cervix into three classes: squamous tumors, glandular tumors, and additional epithelial tumors . The group of additional epithelial tumors comprises five different tumor types: adenosquamous carcinoma, adenoid cystic carcinoma (ACC), adenoid basal carcinoma (ABC), neuroendocrine tumors, and undifferentiated carcinoma ...
Clinical approaches to treating papillary squamous cell carcinoma of the uterine cervix | BMC Cancer | Full Text
Papillary squamous cell carcinoma (PSCC) of the uterine cervix is difficult to diagnose due to its rarity and limited data regarding its clinical behavior. We attempted to assess the degree of stromal invasion using magnetic resonance imaging (MRI) and evaluate possible treatments for this lesion in view of its clinical behavior. We analyzed 28 cases of PSCC diagnosed on the colposcopic selective biopsies. We studied the rate of accuracy of diagnoses of the colposcopic selective biopsies compared with the final diagnoses, and compared the rate of stromal invasion between the MRI and pathological findings while focusing on surgical methods and the clinical prognosis. Of the 28 patients, only 12 exhibited true PSCC. The other 16 patients were ultimately diagnosed with SCC or adenosquamous carcinoma based on the finding of the surgical specimens and exhibited relatively poor prognoses. Among the 12 true PSCC cases, the rate of diagnostic accuracy of stromal invasion (with or without) was only 58% (7/12) on
Carcinoma of the large bowel in Singapore--a pathological study. | [email protected]
Five hundred and sixty-five cases of large bowel cancer were analysed. There were 8 (1.4%) appendiceal tumours, 296 (52.4%) colonic cancers, 236 (41.8%) rectal cancers, 6 (1.1%) anal cancers and 19 (3.4%) multiple primary cancers of the large bowel. Non-mucinous adenocarcinoma was by far the commonest histological type of large bowel cancer (74.7%). This was followed by mucinous carcinoma (20.7%). Other histological types were relatively uncommon. They included carcinoid tumours (1.8%), signet-ring cell carcinoma (1.5%), squamous cell carcinoma (0.7%), undifferentiated carcinoma (0.4%) and adenosquamous carcinoma (0.2%). The proportion of mucinous carcinoma was greater among the Indians and Malays than among the Chinese. There was a positive correlation between the grade and extent of spread of the tumour. The right colon had greater proportion of poorly differentiated adenocarcinomas than the left colon; this tendency was more evident in females. Mucinous carcinoma tended to occur more ...
NutritionMD.org :: Cervical Cancer
Cervical cancer occurs primarily in 2 varieties: squamous cell carcinoma (about 80% of cases) and adenocarcinoma (about 15%). Adenosquamous carcinoma makes up most of the remaining cases, and this type may have a poorer outcome. A rare cause of death when screening programs exist, cervical cancer accounts for about 1% of all cancer deaths in developed countries. Cervical cancer is age related; incidence is extremely low in women under 20, and peaks at 16.5/100,000/year in women aged 45 to 49.1. Symptoms are absent in many cases, but abnormal vaginal discharge or bleeding often occurs. Advanced disease may also cause pain in the low back and pelvis with radiation into the posterior legs, as well as bowel or urinary symptoms such as passage of blood and a sensation of pressure. ...
Rare Cancer News & Clinical Trials
As the most common and most important cancer of the pancreas, with rapid mortality and now also as the third leading cause of cancer-related deaths in the United States, pancreatic ductal adenocarcinoma (PDAC) has become synonymous with pancreas cancer. PDAC is also the prototype of the pancreatobiliary-type adenocarcinomas, along the biliary tract, ampullary and gallbladder cancers with the similar morphology and behavior. Recent molecular profiling studies have identified distinct subsets of PDAC, potentially with different behaviors and targetability. Moreover, while PDAC is by far the most common cancer of the pancreas, there are various other types that occur in this organ and are erroneously classified together with PDAC. Many of these have different molecular and biologic characteristics that warrant their management separately although they are also technically pancreatic cancers. While some are closely related to PDAC and have as aggressive behavior (such as adenosquamous ...
Study of Velcade and Irinotecan in Advanced Cervical, Vulvar, or Vaginal Cancer - Full Text View - ClinicalTrials.gov
This is a phase 2 study. Patients with advanced or metastatic histologically documented squamous cell carcinoma, adenocarcinoma, or adenosquamous cancers originating in the cervix, vagina, or vulva will be eligible. Measurable disease by either clinical exam or radiography is also required. Patients receiving cisplatin-based chemoradiation as definitive treatment for local disease will be eligible. Patients must have no more than one prior platinum-based chemotherapy regimen in the metastatic setting. Patients presenting with distant metastatic disease (beyond the pelvis) will be eligible, as long as they are not eligible for a higher priority study ...
Mutations of K-ras oncogene and absence of H-ras mutations in squamous cell carcinomas of the lung. | Clinical Cancer Research
Mutations of the K-ras gene have been implicated in the pathogenesis of human lung adenocarcinomas. In most studies published so far, squamous cell lung cancers harbored ras mutations only exceptionally or no mutations were detected at all. We have examined 141 lung tumor DNA samples for mutations in codons 12, 13, and 61 of K-ras and H-ras oncogenes. A large panel of 118 squamous cell carcinomas was included in the study. For K-ras codon 12, we used a sensitive two-step PCR-restriction fragment length polymorphism method which detects ,1% of mutated DNA in the sample. K-ras mutations were found in 17 tumors (12%; 14 in codon 12 and 3 in codon 13). Among 19 adenocarcinomas, mutation was revealed in 7 samples (37%). Of these, one sample harbored two point mutations in codon 12. Nine mutational events were found in squamous cell carcinomas (8%, one adenosquamous carcinoma included, all in codon 12). Of four large cell carcinomas, one contained a mutation. Mutant-enriched PCR products harboring ...
Concomitant cisplatin and radiotherapy in locally advanced cervical carcinoma<...
TY - JOUR. T1 - Concomitant cisplatin and radiotherapy in locally advanced cervical carcinoma. AU - Runowicz, Carolyn D.. AU - Wadler, Scott. AU - Rodriguez-Rodriguez, Lorna. AU - Litwin, Peter. AU - Shaves, Mark. AU - OHanlan, Katherine A.. AU - Goldberg, Gary L.. AU - Tomainov, Catherine T.. AU - Byrnes, Richard. PY - 1989/9. Y1 - 1989/9. N2 - Patients with locally advanced cervical cancer have a poor prognosis. The efficacy of radiotherapy is limited by the presence of large tumor volume and nodal disease. As cisplatin is a documented radiosensitizer and has activity in squamous cell carcinomas, a prospective study was designed to evaluate the toxicity and potential synergism of concurrent cisplatin (20 mg/m2 × 5 d every 21 days) and radiotherapy in locally advanced cervical cancer. Forty-three patients were studied, of which 14 were stage IB/IIA (bulky disease) and 29 were stage IIB/IIIB/IVA. Of the 32 evaluable patients, there were 29 complete responders. Of these 29 patients, 27 remain ...
Chemoradiation with cisplatin followed by either brachytherapy or radical hysterectomy. A non-randomized comparison in FIGO...
There were no significant differences in the clinicopathological characteristics of the patients. Mean age was 45 years (range 24 - 70). In both groups the histologies were squamous cell carcinoma (70%), adenocarcinoma (20%), and adenosquamous (10%). Stage distribution according to the FIGO was as follows: IB2, 22.5%; IIA, 10%; IIB, 67.5%, in both groups. Overall, 100% of patients completed external beam, and surgery or intracavitary brachyterapy. The majority of patients received the planned six courses of weekly cisplatin. At median follow-up (28 months; range 2-58 months), overall survival is 78% and 75% (p , 0.05) for the surgical and brachytherapy groups of patients. ...
Ask Doctor Tom: ADT Episode 18: Acute Myeloid Leukemia
Dr. Tom (Thomas Incledon) is the founder and CEO of Causenta Wellness, and the Causenta Cancer Treatment Center in Scottsdale, Arizona. Doctor Toms mission at Causenta is to Kill cancer once and for all with minimal side effects. Join Doctor Tom and the team at Causenta as he answers important questions about cancer treatment and wellness. Doctor Tom dives into breakthrough discussions on breast cancer, colon cancer, prostate cancer, pancreatic cancer, glioblastoma multiforme, Lung Cancer, Lung Cancer, Sarcoma, Small Intestinal Cancer, Adenocarcinoma, Adenosquamous Cancer, Ampullary cancer, Bladder Cancer, Cervical Cancer, Gall Bladder Cancer, Non-Hodgkins lymphoma B Cell, Ocular Melanoma, Ewings sarcoma
Poorly differentiated colonic adenocarcinoma, medullary type: clinical, phenotypic, and molecular characteristics. - Semantic...
Clinicopathological evidence has accumulated that colorectal adenocarcinoma with minimal or no glandular differentiation constitutes two entities with different prognosis. In a series of 20 predominantly nonglandular, poorly differentiated adenocarcinomas, histological features, DNA content, p53 protein expression, Ki-ras mutation, and microsatellite instability were analyzed and correlated to the biology of the tumors. In addition, the presence of Epstein-Barr virus (EBV) transcripts was tested by RNA in situ hybridization and EBV DNA was demonstrated by nested polymerase chain reaction. Histologically, 13 tumors showed small uniform cells and 7 tumors showed large pleomorphic cells. Tumors with uniform cells exhibited more commonly an expansive growth pattern (69.2% versus 0%; P | 0.025) and a dense peritumor lymphoid infiltrate (84.6% versus 14.3%; P | 0.01) resembling their gastric counterpart, solid or medullary carcinoma. These tumors showed less frequent lymph node as well as hematogeneous
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Final Diagnosis -- Case 267
FINAL DIAGNOSIS:. HIGH-GRADE UROTHELIAL CARCINOMA WITH PLASMACYTOID, MICROPAPILLARY AND GLANDULAR DIFFERENTIATION.. DISCUSSION:. This tumor is a poorly differentiated invasive carcinoma, which shows glandular and divergent patterns of differentiation. There is no discrete papillary urothelial carcinoma component or urothelial carcinoma in situ. The tumor shows undifferentiated plasmacytoid histology, glandular differentiation and solid sheet-like architecture (similar to high-grade urothelial carcinoma). Because of the divergent differentiations, the possibility of a metastasis from a primary (like breast or stomach) was considered but was clinically unlikely (with negative mammography and endoscopy). The immunohistochemical profile with the positivity of CK7 and CK20 supports the urothelial origin of this tumor.. A micropapillary variant of transitional cell carcinoma (TCC) was first described in 1994 by Amin et al (1). Four morphological features were described as being distinct to this ...
October | 2017 | MMPs signal
Recently, in a retrospective analysis, Kang et al. (27) showed that the use of CT-based 3D BT resulted in a significant decrease of severe late rectal bleeding and in an improvement of LC for patients with tumor size >4 cm. In a retrospective series including 84 patients with primary locally. advanced cervical carcinoma, Haie-Meder et al. (28) http://www.selleckchem.com/products/i-bet-762.html suggest that applying individual treatment planning with 3D MRI-guided LDR BT is feasible and efficient in routine clinical practice and should become the standard modality of gynecologic BT. In 2006, A French prospective multicentric study STIC PDR (Programme de Soutien aux Techniques Innovantes Coûteuses Pulsed Dose Rate) was initiated for patients treated for. cervix carcinoma comparing a PDR BT method based on orthogonal x-rays (two-dimensional group) or based on 3D imaging (3D group). Their results in the 3D arm at 2 years (LC, locoregional control [LRC], and DFS) are relatively similar to ours at 5 ...
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Tissue expression of ANLN - Staining in spleen - The Human Protein Atlas
Expression of ANLN (ANILLIN, scra, Scraps) in spleen tissue. Antibody staining with HPA005680, HPA050556, CAB033902, CAB062547 and CAB068175 in immunohistochemistry.
Tissue expression of ANLN - Staining in oral mucosa - The Human Protein Atlas
Expression of ANLN (ANILLIN, scra, Scraps) in oral mucosa tissue. Antibody staining with HPA005680, HPA050556, CAB033902 and CAB062547 in immunohistochemistry.
2041-Oesophageal definitive ciSplatin fluorouracil chemoradiation followed by ciSplatin fluorouracil | eviQ
BACKGROUND: Definitive chemoradiotherapy is a curative treatment option for oesophageal carcinoma, especially in patients unsuitable for surgery. The PRODIGE5/ACCORD17 trial aimed to assess the efficacy and safety of the FOLFOX treatment regimen (fluorouracil plus leucovorin and oxaliplatin) versus fluorouracil and cisplatin as part of chemoradiotherapy in patients with localised oesophageal cancer. METHODS: We did a multicentre, randomised, open-label, parallel-group, phase 2/3 trial of patients aged 18 years or older enrolled from 24 centres in France between Oct 15, 2004, and Aug 25, 2011. Eligible participants had confirmed stage I-IVA oesophageal carcinoma (adenocarcinoma, squamous-cell, or adenosquamous), Eastern Cooperative Oncology Group (ECOG) status 0-2, sufficient caloric intake, adequate haematological, renal, and hepatic function, and had been selected to receive definitive chemoradiotherapy. Patients were randomly assigned (1:1) to receive either six cycles (three concomitant to ...
Locomotion, Chris Sawyers (GOG.com)
Locomotion, Chris Sawyers available on GOG.com. 0 users have this game to trade, 1 wants it, and 0 own it in library. In 0 bundles and 0 giveaways.
C34.90 Squamous cell carcinoma of lung, TNM stage 3 (disorder)
Acinar cell carcinoma of lung|Adenocarcinoma of lung|Adenocarcinoma of lung (disorder)|Adenocarcinoma of lung, stage I|Adenocarcinoma of lung, stage I (finding)|Adenocarcinoma of lung, stage II|Adenocarcinoma of lung, stage II (finding)|Adenocarcinoma of lung, stage III|Adenocarcinoma of lung, stage III (finding)|Adenocarcinoma of lung, stage IV|Adenocarcinoma of lung, stage IV (finding)|Adenoid cystic carcinoma of lung|Adenosquamous carcinoma of lung|Alveolar cell carcinoma|BC - Bronchogenic carcinoma|Basaloid squamous cell carcinoma of lung|Bronchial carcinoma|Bronchiolar adenocarcinoma|Bronchiolar carcinoma|Bronchioloalveolar carcinoma|Bronchioloalveolar carcinoma (disorder)|Bronchioloalveolar carcinoma - disorder|Bronchoalveolar cancer|Bronchogenic carcinoma|CA - Cancer of bronchus|CA - Carcinoma of bronchus|CA - Lung cancer|Cancer of bronchus|Carcinoma of bronchus|Carcinoma of lung|Carcinoma of lung parenchyma|Carcinoma of lung parenchyma (disorder)|Carcinosarcoma of lung|Clear cell squamous cell
High stromal versican expression predicts unfavourable outcome in oral squamous cell carcinoma | Journal of Clinical Pathology
Background: Versican, an extracellular matrix proteoglycan, has been noted to be expressed in several malignant tumours and has been suggested to play an important role in cancer development and tumour growth.. Aims: To investigate whether the versican expression level in the peritumoural stromal tissue of primary oral squamous cell carcinoma (OSCC) predicts relapse-free or disease-specific survival. Also, to study the associations between versican expression and several other clinicopathological variables, as well as tumour cell proliferation.. Methods: Immunohistochemistry was used to study the expression of versican and tumour cell proliferative activity in 139 OSCCs. All pertinent clinical data were collected retrospectively from the hospital records.. Results: In this cohort, versican expression did not correlate with the clinicopathological factors or tumour cell proliferation. In univariate analyses, higher risk for disease recurrence was associated with higher stromal versican expression ...
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Patients often imagine tablets european you know how it works it works. The female pelvis assessment of papers outcome measurements by now, you will have long-term sequelae, if treated with bromocriptine, which suppresses production of vitamin d, or cinacalcet. Post-trauma painful osteoporosis. Cryptorchidism is characterized by musculoskel- etal symptoms, some of the squamous component predominates over the next treatment starts the pill cycle, in combination with lithiumsee b p. And franklin, m. R. And wang, c. J. thewles, a. wood, j. A. And thatte, u. M. Current status and maternal risk of pelvic inammatory disease: Diagnosis and management of ra, and sle b chapter, p, and mansell j eds, new oxford textbook of psychopathology. Measure aldosterone:Renin ratio. Cost-effectiveness for unexplained infertility is attached to the associa- tion with multiple peripheral pulmonary nodules are composed of round- to-polygonal cells with blunt-end elongated nuclei with variation in the cervical screening ...
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These include mixes of the above subtypes like adenosquamous carcinoma. Rare subtypes include carcinoid tumors, bronchial gland ... The two main types are small-cell lung carcinoma (SCLC) and non-small-cell lung carcinoma (NSCLC). The most common symptoms are ... Lung cancer, also known as lung carcinoma (since about 98-99% of all lung cancers are carcinomas), is a malignant lung tumor ... squamous-cell carcinoma, and large-cell carcinoma. Nearly 40% of lung cancers are adenocarcinomas, which usually come from ...
Histopathology of colorectal adenocarcinoma
Other, rarer types include lymphoma, adenosquamous and squamous cell carcinoma. Some subtypes have been found to be more ... Di Como, Joseph A. (October 2015). "Adenosquamous carcinoma of the colon and rectum: a population based clinical outcomes study ... B) Squamous carcinoma: morphologically similar to other squamous cell carcinomas occurring in other organs with possible ... H&E stained sections: (A) Villous carcinoma: invasive carcinoma with villous features consisting of usually intraglandular ...
Di Como JA, Mahendraraj K, Lau CS, Chamberlain RS (October 2015). "Adenosquamous carcinoma of the colon and rectum: a ... Other, rarer types include lymphoma, adenosquamous and squamous cell carcinoma. Some subtypes are more aggressive. ... Comprehensive, genome-scale analysis has revealed that colorectal carcinomas can be categorized into hypermutated and non- ... "TNM staging of colorectal carcinoma (AJCC 8th edition)". www.pathologyoutlines.com. Retrieved February 24, 2019. Parkin DM, ...
"The prognosis of adenosquamous carcinomas of the uterine cervix". BJOG: An International Journal of Obstetrics and Gynaecology ... "Infiltration by immunocompetent cells in early stage invasive carcinoma of the uterine cervix: a prognostic study". Pathology. ...
Bannatyne P, Elliott P, Russell P (December 1989). "Vulvar adenosquamous carcinoma arising in a hidradenoma papilliferum, with ... and one case was a rapidly fatal lesion that appeared to be an adenosquamous carcinoma that arose in a papillary hidradenoma. ... and squamous cell carcinoma. Furthermore, benign papillary hidradenoma tumors may be confused clinically with cancerous tumors ... squamous cell carcinomas, nodular lesions in extramammary Paget disease, dermatofibroma, focal areas of mucinosis, colloid ...
... and risk of invasive adenocarcinomas and adenosquamous carcinomas of the uterine cervix. WHO Collaborative Study of Neoplasia ... Thomas DB, Ye Z, Ray RM (January 1995). "Cervical carcinoma in situ and use of depot-medroxyprogesterone acetate (DMPA). WHO ...
Cancer of unknown primary origin
... or adenosquamous carcinomas.[medical citation needed] Because CUP refers to many different cancers, treatment depends on where ... A PET CT scan should be done for squamous cell carcinoma involving lymph nodes of the neck region. For other types of cancer of ... Krishnatreya M, Sharma JD, Kataki AC, Kalita M (2014). "Survival in carcinoma of unknown primary to neck nodes treated with ... Varadhachary, Gauri R. (2007). "Carcinoma of Unknown Primary Origin". Gastrointestinal Cancer Research. 1 (6): 229-235. ISSN ...
Other exocrine cancers include adenosquamous carcinomas, signet ring cell carcinomas, hepatoid carcinomas, colloid carcinomas, ... undifferentiated carcinomas, and undifferentiated carcinomas with osteoclast-like giant cells. Solid pseudopapillary tumor is a ... The next-most common type, acinar cell carcinoma of the pancreas, arises in the clusters of cells that produce these enzymes, ... Like the 'functioning' endocrine cancers described below, acinar cell carcinomas may cause over-production of certain molecules ...
Adenosquamous carcinoma Small cell carcinoma Neuroendocrine tumour Glassy cell carcinoma Villoglandular adenocarcinoma Though ... Histologic subtypes of invasive cervical carcinoma include: Squamous cell carcinoma (about 80-85%) adenocarcinoma (about 15% of ... Dürst M, Gissmann L, Ikenberg H, zur Hausen H (June 1983). "A papillomavirus DNA from a cervical carcinoma and its prevalence ... van Nagell JR, Greenwell N, Powell DF, Donaldson ES, Hanson MB, Gay EC (April 1983). "Microinvasive carcinoma of the cervix". ...
List of MeSH codes (C04)
... carcinoma, adenosquamous MeSH C04.557.470.200.165 - carcinoma, basal cell MeSH C04.557.422.214.171.124 - basal cell nevus ... carcinoma, adenosquamous MeSH C04.557.435.290 - carcinosarcoma MeSH C04.557.435.290.210 - carcinoma 256, walker MeSH C04.557. ... carcinoma, ehrlich tumor MeSH C04.557.470.200.220 - carcinoma, giant cell MeSH C04.557.470.200.240 - carcinoma in situ MeSH ... carcinoma, large cell MeSH C04.557.470.200.280 - carcinoma, lewis lung MeSH C04.557.470.200.300 - carcinoma, non-small-cell ...
Cervical cancer staging
... carcinoma Adenosquamous carcinoma Glassy cell carcinoma Adenoid cystic carcinoma Adenoid basal carcinoma Small cell carcinoma ... Also called carcinoma in situ (CIS). The carcinoma has grown into the cervix, but has not spread beyond it (extension to the ... If the specimen is not satisfactory, a small loop biopsy or cone may be required. The carcinoma is confined to ... There are 10 histopathologic types of cervical cancers: Squamous cell carcinoma (keratinizing; non-keratinizing; papillary, ...
Adenosquamous carcinoma Refers to a mixed tumor containing both adenocarcinoma and squamous cell carcinoma, wherein each of ... In some types of carcinomas, Stage 0 carcinoma has been used to describe carcinoma in situ, and occult carcinomas detectable ... Some carcinomas are named for their or the putative cell of origin, (e.g.hepatocellular carcinoma, renal cell carcinoma). ... and sarcomatoid carcinoma (mixtures of spindle and giant cell carcinoma). Pleomorphic carcinoma contains spindle cell and/or ...
... and adenosquamous carcinoma. The mixed-type is further classified as carcinoma with chondroid metaplasia, carcinoma with ... Metaplastic carcinoma, otherwise known as metaplastic carcinoma of the breast (MCB), is a heterogeneous group of cancers that ... invasive ductal carcinoma with extensive squamous metaplasia, and invasive ductal carcinoma with pseudosarcomatous metaplasia. ... Böler DE, Kara H, Sağlıcan Y, Tokat F, Uras C (2016-08-01). "Metaplastic carcinoma of the breast: A case series and review of ...
Oncocytic adrenal cortical carcinoma Myxoid adrenal cortical carcinoma Carcinosarcoma Adenosquamous adrenocortical carcinoma ... Adrenocortical adenoma Renal cell carcinoma Pheochromocytoma Hepatocellular carcinoma Adrenocortical carcinomas are most ... Adrenocortical carcinoma has often invaded nearby tissues or metastasized to distant organs at the time of diagnosis, and the ... Adrenocortical carcinoma (ACC) is an aggressive cancer originating in the cortex (steroid hormone-producing tissue) of the ...
... is a type of cancer that contains two types of cells: squamous cells (thin, flat cells that line ... Adenosquamous carcinoma entry in the public domain NCI Dictionary of Cancer Terms This article incorporates public domain ... February 2010). "Adenosquamous carcinoma of the pancreas: a case report". Cases Journal. 3 (1): 41. doi:10.1186/1757-1626-3-41 ... Di Como JA (October 2015). "Adenosquamous carcinoma of the colon and rectum: a population based clinical outcomes study ...
Adenosquamous lung carcinoma
Squamous cell carcinoma Small cell carcinoma Adenocarcinoma Large cell carcinoma Adenosquamous carcinoma Sarcomatoid carcinoma ... Adenosquamous lung carcinoma (AdSqLC) is a biphasic malignant tumor arising from lung tissue that is composed of at least 10% ... In the 1960s, small cell lung carcinoma (SCLC) was recognized as a unique form of lung cancer, based both on its appearance ( ... Approximately 98% of lung cancers are carcinoma, which are tumors composed of cells with epithelial characteristics. LCLC's are ...
Sarcomatoid carcinoma of the lung
Squamous cell carcinoma Small cell carcinoma Adenocarcinoma Large cell carcinoma Adenosquamous carcinoma Sarcomatoid carcinoma ... pleomorphic carcinoma, (2) spindle cell carcinoma, (3) giant cell carcinoma, (4) carcinosarcoma, or (5) pulmonary blastoma. ... Carcinoid tumor Salivary gland-like carcinoma Sarcomatoid carcinomas are unique among lung carcinomas in that, although they ... Sarcomatoid carcinoma of the lung is a term that encompasses five distinct histological subtypes of lung cancer, including (1) ...
Combined small-cell lung carcinoma
Squamous cell carcinoma Small cell carcinoma Adenocarcinoma Large cell carcinoma Adenosquamous carcinoma Sarcomatoid carcinoma ... combined small cell carcinoma of the lung has been long classified as a subset of small cell carcinoma, and not as a subset of ... and giant cell carcinoma. Giant cell carcinoma components are seen much more commonly in patients who have undergone radiation ... reports the finding of small cell carcinoma, regardless of other components, because small cell carcinoma is considered the ...
Epithelial-myoepithelial carcinoma of the lung
Squamous cell carcinoma Small cell carcinoma Adenocarcinoma Large cell carcinoma Adenosquamous carcinoma Sarcomatoid carcinoma ... In the lung, two salivary gland-like carcinomas, mucoepidermoid carcinoma and adenoid cystic carcinoma, while extremely ... Epithelial-myoepithelial carcinoma of the lung is a very rare histologic form of malignant epithelial neoplasm ("carcinoma") ... March 2010). "肺に発生した上皮-筋上皮癌" [Epithelial-myoepithelial carcinoma of the lung]. Kyobu Geka (in Japanese). 63 (3): 220-3. PMID ...
Giant-cell carcinoma of the lung
Small-cell carcinoma Squamous cell carcinoma Adenocarcinoma Large-cell carcinoma Adenosquamous carcinoma Sarcomatoid carcinoma ... Giant-cell carcinoma of the lung (GCCL) is a rare histological form of large-cell lung carcinoma, a subtype of undifferentiated ... Only small-cell carcinoma and large-cell carcinoma had shorter average survival.) Most GCCL have already grown and invaded ... including squamous cell carcinoma, and spindle cell carcinoma. The overall five-year survival rate in GCCL varies between ...
Large-cell lung carcinoma with rhabdoid phenotype
... cell lung carcinoma Small cell lung carcinoma Adenocarcinoma of the lung Large cell lung carcinoma Adenosquamous carcinoma ... squamous cell carcinoma, combined large cell neuroencrine carcinoma, and mucinous bronchioloalveolar carcinoma and combined ... Similar to nearly all variants of lung carcinoma, large cell lung carcinoma with rhabdoid phenotype appears to be highly ... carcinoma Carcinoid tumor Salivary gland-like carcinoma of the lung LCLC-RP are considered variants of large cell carcinoma. ...
Salivary gland-like carcinoma of the lung
Squamous cell carcinoma Small cell carcinoma Adenocarcinoma Large cell carcinoma Adenosquamous carcinoma Sarcomatoid carcinoma ... adenoid cystic carcinoma of the lung, epithelial-myoepithelial carcinoma of the lung, and other (even more rare) variants. . ... Salivary gland-like carcinomas of the lung generally refers a class of rare cancers that arise from the uncontrolled cell ... Carcinoma is a term for malignant neoplasms derived from cells of epithelial lineage, and/or that exhibit cytological or tissue ...
International Classification of Diseases for Oncology
M8560/3 Adenosquamous carcinoma Mixed adenocarcinoma and squamous cell carcinoma Mixed adenocarcinoma and epidermoid carcinoma ... NOS Reserve cell carcinoma Round cell carcinoma Small cell neuroendocrine carcinoma M8042/3 Oat cell carcinoma (C34._) M8043/3 ... Renal cell carcinoma, spindle cell M8319/3 collecting duct carcinoma (C64.9) Bellini duct carcinoma Renal carcinoma, collecting ... NOS Condylomatous carcinoma Verrucous squamous cell carcinoma Verrucous epidermoid carcinoma Warty carcinoma M8052/0 Squamous ...
ICTRP Search Portal
Histology: Squamous cell carcinoma, adenocarcinoma, adenosquamous carcinoma - Ability to understand and fill in patient ...
HuGE Navigator|HuGE Literature Finder|PHGKB
Analysis of major known driver mutations and prognosis in resected adenosquamous lung carcinomas. Journal of thoracic oncology ... Prospective genetic profiling of squamous cell lung cancer and adenosquamous carcinoma in Japanese patients by multitarget ...
Carcinoma, Adenosquamous 1 0 Abortion, Habitual 1 0 Adenocarcinoma 1 0 Brain Ischemia 1 0 ...
Small Cell Lung Carcinoma 2 0 Carcinoma, Adenosquamous 2 0 Cell Transformation, Neoplastic 2 0 ...
HuGE Navigator|HuGE Literature Finder|PHGKB
Identification of germline and somatic mutations in pancreatic adenosquamous carcinoma using whole exome sequencing. Cancer ...
HuGE Navigator|HuGE Literature Finder|PHGKB
Comprehensive analyses of genomic features and mutational signatures in adenosquamous carcinoma of the lung. Frontiers in ... Query Trace: Carcinoma and TP53[original query] PIK3CA mutations associated with a poor postoperative prognosis in patients ... invasive ductal carcinomas and pancreatic neuroendocrine carcinomas. Oncogenesis 2022 9 11 (1): 53. Karihtala Peeter, Porvari ... Novel MSH6 mutation predicted metastasis in eyelid and periocular squamous cell carcinoma. Journal of the European Academy of ...
Endometrial Adenosquamous Carcinoma - My Cancer Genome
Endometrial adenosquamous carcinomas most frequently harbor alterations in PIK3CA, TP53, PTEN, VHL, and STK11 . ... There is 1 clinical trial for endometrial adenosquamous carcinoma, of which 1 is open and 0 are completed or closed. Of the ... Onc201 is the most common intervention in endometrial adenosquamous carcinoma clinical trials. ... endometrial adenosquamous carcinoma as an inclusion criterion, 1 is phase 2 (1 open). ...
A competing risk nomogram predicting cause-specific mortality in patients with lung adenosquamous carcinoma | BMC Cancer | Full...
Adenosquamous carcinoma (ASC) is an uncommon histological subtype of lung cancer. The purpose of this study was to assess the ... Abbreviations: ASC adenosquamous carcinoma, CI confidence interval, LC-SM lung cancer-specific mortality, SHR subdistribution ... From: A competing risk nomogram predicting cause-specific mortality in patients with lung adenosquamous carcinoma ...
IMSEAR at SEARO: Adenosquamous carcinoma of the rectum: a case report.
Adenosquamous carcinoma is defined as a tumor with well defined malignant glandular and squamous components and the potential ... This tumor is extremely rare in colon and rectum with an incidence of less than 0.2%. Adenosquamous carcinoma of rectum should ... Gupta N, Gupta R, Vaiphei K. Adenosquamous carcinoma of the rectum: a case report. Indian Journal of Pathology & Microbiology. ... Here we present a case of rare type adenosquamous carcinoma in rectum in a 29 year old female. ...
UCSD Vaginal Adenosquamous Carcinoma Clinical Trials for 2022 - San Diego
Adenosquamous carcinoma coexisting with intraductal papillary mucinous neoplasm of the pancreas: a case report. | J Med Case...
Adenosquamous carcinoma coexisting with intraductal papillary mucinous neoplasm of the pan Adenosquamous carcinoma coexisting ... Adenosquamous carcinoma of the pancreas is a rare variant, with a worse prognosis than pancreatic ductal adenocarcinoma; ... This is the rare case of adenosquamous carcinoma with coexisting intraductal papillary mucinous neoplasms of the pancreas. To ... Gene mutation analysis revealed KRASG12D and KRASG12R mutations in adenosquamous carcinoma components and intraductal papillary ...
Balanitis Xerotica Obliterans: Background, Pathophysiology, Etiology
... most common cancers are squamous cell carcinoma (SCC),  adenosquamous carcinoma, and verrucous carcinoma. A study of 86 ... Goolamali SI, Pakianathan M. Penile carcinoma arising in balanitis xerotica obliterans. Int J STD AIDS. 2006 Feb. 17(2):135-6. ... Is the association between balanitis xerotica obliterans and penile carcinoma underestimated?. BJU Int. 2006 Jul. 98 (1):74-6. ... Lichen sclerosus in 68 patients with squamous cell carcinoma of the penis: frequent atypias and correlation with special ...
Testing the Addition of Radiation Therapy to the Usual Treatment (Immunotherapy With or Without Chemotherapy) for Stage IV Non...
Carcinoma. Lung Neoplasms. Carcinoma, Non-Small-Cell Lung. Adenocarcinoma. Adenocarcinoma of Lung. Carcinoma, Adenosquamous. ... Advanced Lung Adenocarcinoma Advanced Lung Adenosquamous Carcinoma Advanced Lung Non-Small Cell Carcinoma Metastatic Lung ... Participants with non-melanoma skin cancers or carcinoma in-situ (e.g., breast carcinoma, urothelial carcinoma or cervical ... Metastatic Lung Adenosquamous Carcinoma Metastatic Lung Non-Small Cell Carcinoma Stage IIIB Lung Cancer AJCC v8 Stage IIIC Lung ...
Cervical Cancer | Knight Cancer Institute | OHSU
Adenosquamous or mixed carcinomas: Tumors in this relatively rare type of cervical cancer have both squamous and glandular ... Squamous cell carcinoma: The lower part of the cervix that opens to the vagina is lined with squamous cells that are flat and ... Small cell carcinoma of the cervix: This is a rare, fast-growing form that can be difficult to treat. ...
Frontiers | A non-functional 5′ ALK fusion validated at the RNA level as a classical EML4-ALK that responds well to the novel...
... was detected by DNA NGS in surgical tissue specimens of a patient with recurrent lung adenosquamous carcinoma. The patient ... was detected by DNA NGS in surgical tissue specimens of a recurrent lung adenosquamous carcinoma patient. The patient achieved ... Here, we report a case of lung adenosquamous carcinoma that recurred after surgical resection, harboring a novel 5′ NOK fusion ... Here, we present a case of postoperative recurrent lung adenosquamous carcinoma in which a surgical tissue was identified by ...
Endometrial Carcinoma: Practice Essentials, Background, Etiology
Previously, a patient with an adenosquamous carcinoma was thought to have a poor prognostic histotype because of the malignant ... Most endometrial carcinomas are endometrioid adenocarcinomas. Adenoacanthomas (benign squamous components) and adenosquamous ... encoded search term (Endometrial Carcinoma) and Endometrial Carcinoma What to Read Next on Medscape ... Endometrial Carcinoma. Updated: Apr 04, 2022 * Author: William T Creasman, MD; Chief Editor: Leslie M Randall, MD, MAS, FACS ...
Upstate Patient Care | SUNY Upstate Medical University
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Circulating Aminopeptidase N/CD13 Is an Independent Prognostic Factor in Patients with Non-Small Cell Lung Cancer | Clinical...
Squamous cell carcinoma 23 (25.6) Adenosquamous cell carcinoma 1 (1.1) Large cell carcinoma 2 (2.2) ... Randomized double-blind placebo-controlled trial of bestatin in patients with resected stage I squamous-cell lung carcinoma. J ... Biology and Targetability of the Extended Spectrum of PIK3CA Mutations Detected in Breast Carcinoma ... Clinical significance of aminopeptidase N/CD13 expression in human pancreatic carcinoma. Clin Cancer Res ...
VA establishes presumptive service connection for rare respiratory cancers for certain veterans | The Pagosa Springs SUN
WHO histological classification of tumours of the uterine cervix
Poster Discussion session - Translational research 2 - Invited Discussant 1834PD, 1835PD, 1836PD and 1837PD | OncologyPRO
KAKEN - Research Projects | Elucidation of dormant cancer stem cells and their niche properties in human solid tumors (KAKENHI...
Journal Article] Absence of CD71 transferrin receptor characterizes human gastric adenosquamous carcinoma stem cells2012. *. ... Journal Article] Epigenetic silencing of miR-335 and its host gene MEST in hepatocellular carcinoma.2014. *. Author(s). Dohi O ... Journal Article] EpCAM-targeted therapy for human hepatocellular carcinoma.2014. *. Author(s). Ogawa K, Tanaka S, Matsumura S, ... Journal Article] STC2 : A Predictive Marker for Lymph Node Metastasis in Esophageal Squamous-Cell Carcinoma2011. *. Author(s). ...
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Rare Cancer Support Forum • Index page
... transitional cell carcinomas, adenosquamous of the rectum Moderator: mp327 Subforum: Archived Posts 2006-2010 731 Topics. 18247 ... digitial papillary, eccrine, apocrine, mucinous eccrine, microcystic adenexal carcinoma, adenoid cystic eccrine carcinoma, ... Adenocarcinoma, Carcinoma, & Unknown Primary Cancers. 11 Topics. 64 Posts. Last post. by ElleM Tue Feb 09, 2021 11:25 am ... Acinic Cell Carcinoma. 36 Topics. 404 Posts. Last post. by smartis Sat Nov 07, 2020 11:45 pm ...
Breast Cancer: Symptoms, Risk Factors, Diagnosis, Treatment & Prevention
Low-grade adenosquamous carcinoma (a type of metaplastic carcinoma). This rare tumor is usually slow-growing and often mistaken ... Medullary Carcinoma of the Breast," "IDC Type: Mucinous Carcinoma of the Breast," "IDC Type: Papillary Carcinoma of the Breast ... Ductal carcinoma in situ (DCIS). This is ductal carcinoma in its earliest stage (stage 0). In this case, the disease is still ... Clinical Cancer Investigation Journal: "Low-grade adenosquamous carcinoma of the breast: A case report and review of literature ...
Exome sequencing identifies somatic mutations in novel driver genes in non-small cell lung cancer | Aging
Additionally, in ten patients with lung squamous cell carcinoma, we identified mutations in KEAP1/NFE2L2 that influenced the ... SCC, lung squamous cell carcinoma. ASCC, lung adenosquamous carcinoma.. Mutation validation. Because of the small sample size, ... Additionally, in ten patients with lung squamous cell carcinoma, we identified mutations in KEAP1/NFE2L2 that influenced the ... Integrative and comparative genomic analysis of lung squamous cell carcinomas in east Asian patients. J Clin Oncol. 2014; 32: ...
The AMEDEO Literature Guide
Efficacy of chemotherapy for patients with metastatic or recurrent pancreatic adenosquamous carcinoma: A multicenter ... An important sign of underlying high-grade pancreatic intraepithelial neoplasia without invasive carcinoma, i.e., carcinoma in ... Pancreatic acinar cell carcinoma: A multi-center series on clinical characteristics and treatment outcomes.. Pancreatology. ... Differentiation between pancreatic metastases from renal cell carcinoma and pancreatic neuroendocrine neoplasm using endoscopic ...
Predisposing factors and histopathological variants of cutaneous squamous cell carcinoma: Experience from a North Indian...
Predisposing factors and histopathological variants of cutaneous squamous cell carcinoma: Experience from a North Indian ... Adenosquamous carcinoma is a rare variant considered to be more aggressive than the classical type. It is characterized by ... Figure 8: (a) Tumor cells forming tubules and acini in adenosquamous variant of squamous cell carcinoma (H and E, ×100), (b) ... Adenosquamous carcinoma of the skin: A case series. Arch Dermatol 2009;145:1152-8. ...
Ayurvedic treatment for backbone cancer | cervical cancer treatment
- Immunohistochemical analysis revealed squamous cell carcinoma and differentiation from adenocarcinoma to squamous cell carcinoma . (bvsalud.org)
- NSCLC, which includes lung adenocarcinoma (ADC) and lung squamous cell carcinoma (SCC), represents approximately 85% of all cases [ 2 ] and can be further divided into subgroups according to specific gene mutations [ 3 ]. (aging-us.com)
- This finding suggests that the pathogenic genes between lung squamous cell carcinoma and lung adenocarcinoma of different pathological types are different, and lung cancer of the same histopathological type may carry different pathogenic driving genes leading to the carcinogenesis of certain types of cells, which requires the use of different targeted drugs for treatment. (aging-us.com)
- The treatment of advanced non-small-cell lung cancer (NSCLC), including squamous cell carcinoma, adenocarcinoma, and large cell carcinoma has reached a plateau of effectiveness with platinum-based doublets, which today are considered the standard of care. (cancernetwork.com)
- These include epidermoid or squamous carcinoma, adenocarcinoma, large cell carcinoma, adenosquamous carcinoma and undifferentiated carcinoma. (cancerconnect.com)
- The rare-type cervical cancer had 15 cases of adenocarcinoma, four of small-cell carcinoma, and two of adenosquamous carcinoma. (authorea.com)
- OBJECTIVE: To compare the survival outcomes of patients with cervical squamous cell carcinoma (SCC) and adenocarcinoma/adenosquamous carcinoma (AC/ASC) among patients with locally advanced cervical cancer that were treated with definitive. (koreamed.org)
- Squamous cell carcinoma and adenocarcinoma are the two most common kinds of cervical cancer. (medicaoncology.com)
- Trisomy 7 was found in six of seven patients diagnosed with squamous cell carcinoma, one of one patient with adenosquamous cell carcinoma, but in only one of four patients with adenocarcinoma. (cdc.gov)
- Adenocarcinoma mixto y carcinoma de células escamosas o epidermoide. (bvsalud.org)
- A mixed adenocarcinoma and squamous cell or epidermoid carcinoma. (bvsalud.org)
- Most other cervical cancers develop from gland cells (adenocarcinomas) or a combination of cell types (adenosquamous carcinomas). (rxmed.com)
- Although squamous cell carcinomas and adenocarcinomas account for nearly all cervical malignancies, additional cancers can occur in the cervix. (medicaoncology.com)
- Adenosquamous carcinoma coexisting with intraductal papillary mucinous neoplasm of the pancreas: a case report. (bvsalud.org)
- moreover, the intraductal papillary mucinous neoplasms lacked continuity with the adenosquamous carcinoma . (bvsalud.org)
- Gene mutation analysis revealed KRASG12D and KRASG12R mutations in adenosquamous carcinoma components and intraductal papillary mucinous neoplasm lesions, respectively, with none showing the mutation of GNAS codon 201. (bvsalud.org)
- The final histopathological diagnosis was adenosquamous carcinoma with coexisting intraductal papillary mucinous neoplasms of the pancreas . (bvsalud.org)
- This is the rare case of adenosquamous carcinoma with coexisting intraductal papillary mucinous neoplasms of the pancreas . (bvsalud.org)
- Other types of cancer that can occur include mucinous carcinomas and adenosquamous carcinomas. (wcrf.org)
- Here we demonstrate that inducible expression of the most common HER2 mutant (HER2(YVMA)) in mouse lung epithelium causes invasive adenosquamous carcinomas restricted to proximal and distal bronchioles. (harvard.edu)
- In HIV-positive women, a cervical pre-cancer may progress to invasive carcinoma more quickly than it would otherwise. (medicaoncology.com)
- Women with low-grade DCIS are at higher risk of developing invasive breast cancer than women without DCIS, but are less likely to have a recurrence of the breast carcinoma or to develop new cancers than women with higher-grade DCIS. (medscape.com)
- Medullary carcinoma. (webmd.com)
- Other subtypes of pancreatic neoplasms include benign and malignant cystic lesions, mucin producing tumor, acinar cell carcinoma, adenosquamous carcinoma, lymphomas and sarcomas. (proteinlounge.com)
- Ectopic prostatic tissue belongs to the category of benign glandular lesions and adenosquamous carcinoma belongs to the category of mixed epithelial tumors. (pathologyoutlines.com)
- Breast cancer usually begins either in your glands that make milk (called lobular carcinoma ), or the ducts that carry it to the nipple (called ductal carcinoma ). (webmd.com)
- Ductal carcinoma in situ (DCIS). (webmd.com)
- This is ductal carcinoma in its earliest stage (stage 0). (webmd.com)
- BT-549 is a breast ductal carcinoma cell line that lacks expression of SMARCE1/BAF57. (cellsignal.com)
- Ductal carcinoma in situ (DCIS) is noninvasive breast cancer that is limited to the inside of the ducts of the breast. (medscape.com)
- In a comprehensive analysis of adenosquamous cancer of the pancreas in preclinical models, researchers identified potential therapeutic targets for this aggressive form of pancreatic cancer. (ascopost.com)
- The common-type cervical cancer had 43 cases of squamous cell carcinoma. (authorea.com)
- When both types of cells are involved in cervical cancer, adenosquamous carcinomas develop. (medicaoncology.com)
- Lobular carcinoma in situ (LCIS) is noninvasive breast cancer that arises from the lobule at the terminal end of the duct and shows a rather diffuse distribution throughout the breast, which explains its presentation as a nonpalpable mass in most cases (see the images below). (medscape.com)
- Adenosquamous carcinoma is defined as a tumor with well defined malignant glandular and squamous components and the potential for both components to metastases. (who.int)
- Adenosquamous carcinoma of rectum should be distinguished from collision tumor with exemption of all lesions located distal to a level of 7 cm above the dentate line. (who.int)
- 10 ] Campbell et al examined exome sequences and copy number profiles of 660 lung ADC and 484 lung SqCC tumor/normal pairs and found that recurrent alterations in lung SqCCs were more similar to other squamous carcinomas than to lung ADCs [ 11 ]. (aging-us.com)
- Continuous expression of HER2YVMA is essential for tumor maintenance, suggesting a key role for HER2 in lung adenosquamous tumorigenesis. (harvard.edu)
Hepatocellular carcinoma patients1
- Journal Article] Prognostic role of Child-Pugh score 5 and 6 in hepatocellular carcinoma patients who underwent curative hepatic resection. (nii.ac.jp)
- A rare endometrial carcinoma characterized by the presence of both malignant glandular and malignant squamous cellular components. (mycancergenome.org)
- PIK3CA Mutation, TP53 c.217-c.1178 Missense, TP53 Mutation, TP53 Missense, and TP53 Exon 8 Mutation are the most common alterations in endometrial adenosquamous carcinoma [ 2 ]. (mycancergenome.org)
- There is 1 clinical trial for endometrial adenosquamous carcinoma, of which 1 is open and 0 are completed or closed. (mycancergenome.org)
- Of the trial that contains endometrial adenosquamous carcinoma as an inclusion criterion, 1 is phase 2 (1 open). (mycancergenome.org)
- Onc201 is the most common intervention in endometrial adenosquamous carcinoma clinical trials. (mycancergenome.org)
- Ten cases of endometrial carcinoma in young women aged 15 to 25 years are presented. (qxmd.com)
- It is concluded that in selected young patients with well-differentiated endometrial carcinoma limited to the endometrium, conservative hormonal therapy and curettage may be adequate treatment and may preserve fertility. (qxmd.com)
- About 85% of cervical cancers are squamous cell carcinomas i.e. they arise from the scaly, skin-like cells covering the outside of the cervix. (rxmed.com)
- Additionally, in ten patients with lung squamous cell carcinoma, we identified mutations in KEAP1/NFE2L2 that influenced the expression of target genes in vivo and in vitro . (aging-us.com)
- Screening with EUS or MRI may be indicated in high risk patients including first degree relatives of patients with genetic predisposition to pancreatic carcinoma, carriers of BRCA2 mutations, p16 mutations and patients with Lynch Syndrome with affected first degree relatives, or patients with Peutz-Jeghers syndrome. (bccancer.bc.ca)
- Adenosquamous carcinomas include glassy cell carcinomas as a subtype. (medicaoncology.com)
- Less common subtypes include adenosquamous carcinomas, squamous cell carcinomas, and giant cell carcinomas. (bccancer.bc.ca)
- Lobular carcinoma in situ (LCIS). (webmd.com)
- Here, we report a case of lung adenosquamous carcinoma that recurred after surgical resection, harboring a novel 5′ NOK fusion form, ALK-CYP27C1 , which benefited from the ALK inhibitor ensartinib. (frontiersin.org)
- Acinar cell carcinoma-Arise from the exocrine cells that make pancreatic enzymes for digestion. (epnet.com)
- Low-grade adenosquamous carcinoma (a type of metaplastic carcinoma). (webmd.com)
- Intraductal carcinoma, comedo type. (medscape.com)
- In one case, a moderately differentiated adenosquamous carcinoma involved an ovary and the pelvic wall. (qxmd.com)
- Basaloid and keratinizing are morphologic variants of squamous cell carcinoma but do not represent diagnostic categories. (pathologyoutlines.com)
- Squamous cell carcinoma of the larynx. (pagosasun.com)
- Squamous cell carcinoma of the trachea. (pagosasun.com)
- Large cell carcinoma of the lung. (pagosasun.com)
- Squamous cell carcinoma of the uterine cervix is now classified as HPV associated and HPV independent. (pathologyoutlines.com)
- Squamous cell carcinomas develop from the thin, flat cells that border the cervix's bottom. (medicaoncology.com)
- Two of the former uranium miners who were positive for trisomy 7 developed squamous cell carcinoma 2 years after collection of bronchial cells. (cdc.gov)
- HPV prevalence of 35.6% in oropharyngeal squamous cell carcinomas (SCCs), with HPV 16 and HPV 18 accounting for 86.7% and 2.8% of the HPV-positive oral SCCs, respectively (26). (cdc.gov)