Carcinoma
Carcinoma, Squamous Cell
Carcinoma, Hepatocellular
A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
Carcinoma in Situ
Carcinoma, Papillary
Carcinoma, Ductal, Breast
Carcinoma, Basal Cell
A malignant skin neoplasm that seldom metastasizes but has potentialities for local invasion and destruction. Clinically it is divided into types: nodular, cicatricial, morphaic, and erythematoid (pagetoid). They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck area and the remaining 15% on the trunk and limbs. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1471)
Immunohistochemistry
Carcinoma, Transitional Cell
Carcinoma, Bronchogenic
Carcinoma, Intraductal, Noninfiltrating
Carcinoma, Adenoid Cystic
Carcinoma characterized by bands or cylinders of hyalinized or mucinous stroma separating or surrounded by nests or cords of small epithelial cells. When the cylinders occur within masses of epithelial cells, they give the tissue a perforated, sievelike, or cribriform appearance. Such tumors occur in the mammary glands, the mucous glands of the upper and lower respiratory tract, and the salivary glands. They are malignant but slow-growing, and tend to spread locally via the nerves. (Dorland, 27th ed)
Carcinoma, Small Cell
Tumor Markers, Biological
Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.
Carcinoma, Medullary
A carcinoma composed mainly of epithelial elements with little or no stroma. Medullary carcinomas of the breast constitute 5%-7% of all mammary carcinomas; medullary carcinomas of the thyroid comprise 3%-10% of all thyroid malignancies. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1141; Segen, Dictionary of Modern Medicine, 1992)
Carcinoma, Lobular
A infiltrating (invasive) breast cancer, relatively uncommon, accounting for only 5%-10% of breast tumors in most series. It is often an area of ill-defined thickening in the breast, in contrast to the dominant lump characteristic of ductal carcinoma. It is typically composed of small cells in a linear arrangement with a tendency to grow around ducts and lobules. There is likelihood of axillary nodal involvement with metastasis to meningeal and serosal surfaces. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1205)
Carcinoma, Neuroendocrine
A group of carcinomas which share a characteristic morphology, often being composed of clusters and trabecular sheets of round "blue cells", granular chromatin, and an attenuated rim of poorly demarcated cytoplasm. Neuroendocrine tumors include carcinoids, small ("oat") cell carcinomas, medullary carcinoma of the thyroid, Merkel cell tumor, cutaneous neuroendocrine carcinoma, pancreatic islet cell tumors, and pheochromocytoma. Neurosecretory granules are found within the tumor cells. (Segen, Dictionary of Modern Medicine, 1992)
Prognosis
Neoplasm Staging
Gene Expression Regulation, Neoplastic
Tumor Cells, Cultured
Carcinoma, Mucoepidermoid
A tumor of both low- and high-grade malignancy. The low-grade grow slowly, appear in any age group, and are readily cured by excision. The high-grade behave aggressively, widely infiltrate the salivary gland and produce lymph node and distant metastases. Mucoepidermoid carcinomas account for about 21% of the malignant tumors of the parotid gland and 10% of the sublingual gland. They are the most common malignant tumor of the parotid. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p575; Holland et al., Cancer Medicine, 3d ed, p1240)
Carcinoma, Endometrioid
Head and Neck Neoplasms
Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)
Carcinoma, Embryonal
A highly malignant, primitive form of carcinoma, probably of germinal cell or teratomatous derivation, usually arising in a gonad and rarely in other sites. It is rare in the female ovary, but in the male it accounts for 20% of all testicular tumors. (From Dorland, 27th ed & Holland et al., Cancer Medicine, 3d ed, p1595)
Carcinoma, Merkel Cell
A carcinoma arising from MERKEL CELLS located in the basal layer of the epidermis and occurring most commonly as a primary neuroendocrine carcinoma of the skin. Merkel cells are tactile cells of neuroectodermal origin and histologically show neurosecretory granules. The skin of the head and neck are a common site of Merkel cell carcinoma, occurring generally in elderly patients. (Holland et al., Cancer Medicine, 3d ed, p1245)
Carcinoma, Ductal
Lymphatic Metastasis
Ovarian Neoplasms
Adrenocortical Carcinoma
A malignant neoplasm of the ADRENAL CORTEX. Adrenocortical carcinomas are unencapsulated anaplastic (ANAPLASIA) masses sometimes exceeding 20 cm or 200 g. They are more likely to be functional than nonfunctional, and produce ADRENAL CORTEX HORMONES that may result in hypercortisolism (CUSHING SYNDROME); HYPERALDOSTERONISM; and/or VIRILISM.
Carcinoma, Verrucous
A variant of well-differentiated epidermoid carcinoma that is most common in the oral cavity, but also occurs in the larynx, nasal cavity, esophagus, penis, anorectal region, vulva, vagina, uterine cervix, and skin, especially on the sole of the foot. Most intraoral cases occur in elderly male abusers of smokeless tobacco. The treatment is surgical resection. Radiotherapy is not indicated, as up to 30% treated with radiation become highly aggressive within six months. (Segen, Dictionary of Modern Medicine, 1992)
Carcinoma, Signet Ring Cell
Neoplasm Metastasis
Neoplasm Proteins
Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of NEOPLASMS. Some neoplasm proteins are tumor antigens (ANTIGENS, NEOPLASM), i.e. they induce an immune reaction to their tumor. Many neoplasm proteins have been characterized and are used as tumor markers (BIOMARKERS, TUMOR) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm.
Neoplasm Recurrence, Local
Mice, Nude
Carcinoma, Large Cell
Laryngeal Neoplasms
Retrospective Studies
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Immunoenzyme Techniques
RNA, Messenger
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Neoplasm Transplantation
Neoplasms, Multiple Primary
Survival Rate
Adenocarcinoma, Follicular
Survival Analysis
A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.
Adenocarcinoma, Mucinous
Treatment Outcome
Antigens, Neoplasm
Embryonal Carcinoma Stem Cells
Reverse Transcriptase Polymerase Chain Reaction
Precancerous Conditions
Carcinoma, Papillary, Follicular
Carcinoma, Non-Small-Cell Lung
Tumor Suppressor Protein p53
Endometrial Neoplasms
Adenocarcinoma, Clear Cell
An adenocarcinoma characterized by the presence of varying combinations of clear and hobnail-shaped tumor cells. There are three predominant patterns described as tubulocystic, solid, and papillary. These tumors, usually located in the female reproductive organs, have been seen more frequently in young women since 1970 as a result of the association with intrauterine exposure to diethylstilbestrol. (From Holland et al., Cancer Medicine, 3d ed)
Disease Progression
Colorectal Neoplasms
alpha-Fetoproteins
Apoptosis
One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.
Pancreatic Neoplasms
Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
Cystadenocarcinoma, Serous
A malignant cystic or semicystic neoplasm. It often occurs in the ovary and usually bilaterally. The external surface is usually covered with papillary excrescences. Microscopically, the papillary patterns are predominantly epithelial overgrowths with differentiated and undifferentiated papillary serous cystadenocarcinoma cells. Psammoma bodies may be present. The tumor generally adheres to surrounding structures and produces ascites. (From Hughes, Obstetric-Gynecologic Terminology, 1972, p185)
Carcinoma, Lewis Lung
A carcinoma discovered by Dr. Margaret R. Lewis of the Wistar Institute in 1951. This tumor originated spontaneously as a carcinoma of the lung of a C57BL mouse. The tumor does not appear to be grossly hemorrhagic and the majority of the tumor tissue is a semifirm homogeneous mass. (From Cancer Chemother Rep 2 1972 Nov;(3)1:325) It is also called 3LL and LLC and is used as a transplantable malignancy.
Combined Modality Therapy
Cell Division
Tissue Array Analysis
Disease-Free Survival
Keratins
A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.
Cisplatin
An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.
Follow-Up Studies
Mutation
Cell Transformation, Neoplastic
Biopsy
Tomography, X-Ray Computed
Ki-67 Antigen
Genes, p53
Adenocarcinoma, Papillary
Chemoembolization, Therapeutic
Fatal Outcome
Blotting, Western
Base Sequence
Loss of Heterozygosity
Mammary Neoplasms, Experimental
Kaplan-Meier Estimate
A nonparametric method of compiling LIFE TABLES or survival tables. It combines calculated probabilities of survival and estimates to allow for observations occurring beyond a measurement threshold, which are assumed to occur randomly. Time intervals are defined as ending each time an event occurs and are therefore unequal. (From Last, A Dictionary of Epidemiology, 1995)
Neovascularization, Pathologic
Carcinoma, Basosquamous
Receptor, erbB-2
A cell surface protein-tyrosine kinase receptor that is overexpressed in a variety of ADENOCARCINOMAS. It has extensive homology to and heterodimerizes with the EGF RECEPTOR, the ERBB-3 RECEPTOR, and the ERBB-4 RECEPTOR. Activation of the erbB-2 receptor occurs through heterodimer formation with a ligand-bound erbB receptor family member.
Carcinoembryonic Antigen
Antineoplastic Combined Chemotherapy Protocols
Genes, Tumor Suppressor
Neoplasms, Experimental
Breast
Gene Expression Profiling
Sensitivity and Specificity
Cadherins
Calcium-dependent cell adhesion proteins. They are important in the formation of ADHERENS JUNCTIONS between cells. Cadherins are classified by their distinct immunological and tissue specificities, either by letters (E- for epithelial, N- for neural, and P- for placental cadherins) or by numbers (cadherin-12 or N-cadherin 2 for brain-cadherin). Cadherins promote cell adhesion via a homophilic mechanism as in the construction of tissues and of the whole animal body.
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Papillomaviridae
A family of small, non-enveloped DNA viruses infecting birds and most mammals, especially humans. They are grouped into multiple genera, but the viruses are highly host-species specific and tissue-restricted. They are commonly divided into hundreds of papillomavirus "types", each with specific gene function and gene control regions, despite sequence homology. Human papillomaviruses are found in the genera ALPHAPAPILLOMAVIRUS; BETAPAPILLOMAVIRUS; GAMMAPAPILLOMAVIRUS; and MUPAPILLOMAVIRUS.
Adenocarcinoma, Bronchiolo-Alveolar
A carcinoma thought to be derived from epithelium of terminal bronchioles, in which the neoplastic tissue extends along the alveolar walls and grows in small masses within the alveoli. Involvement may be uniformly diffuse and massive, or nodular, or lobular. The neoplastic cells are cuboidal or columnar and form papillary structures. Mucin may be demonstrated in some of the cells and in the material in the alveoli, which also includes denuded cells. Metastases in regional lymph nodes, and in even more distant sites, are known to occur, but are infrequent. (From Stedman, 25th ed)
Tumor Suppressor Proteins
Carcinoma, Pancreatic Ductal
Liver Cirrhosis
Signal Transduction
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
Transfection
Receptor, Epidermal Growth Factor
A cell surface receptor involved in regulation of cell growth and differentiation. It is specific for EPIDERMAL GROWTH FACTOR and EGF-related peptides including TRANSFORMING GROWTH FACTOR ALPHA; AMPHIREGULIN; and HEPARIN-BINDING EGF-LIKE GROWTH FACTOR. The binding of ligand to the receptor causes activation of its intrinsic tyrosine kinase activity and rapid internalization of the receptor-ligand complex into the cell.
Gene Expression
Case-Control Studies
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
Tumor Burden
Fluorouracil
Down-Regulation
Hyperplasia
Receptors, Estrogen
Xenograft Model Antitumor Assays
Risk Factors
Neoplasm Grading
Carcinoma, Giant Cell
Niacinamide
An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and PELLAGRA. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
Gene Amplification
A selective increase in the number of copies of a gene coding for a specific protein without a proportional increase in other genes. It occurs naturally via the excision of a copy of the repeating sequence from the chromosome and its extrachromosomal replication in a plasmid, or via the production of an RNA transcript of the entire repeating sequence of ribosomal RNA followed by the reverse transcription of the molecule to produce an additional copy of the original DNA sequence. Laboratory techniques have been introduced for inducing disproportional replication by unequal crossing over, uptake of DNA from lysed cells, or generation of extrachromosomal sequences from rolling circle replication.
Papilloma
Keratin-7
In Situ Hybridization, Fluorescence
Ureteral Neoplasms
Lymph Nodes
Up-Regulation
Cell Survival
Predictive Value of Tests
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Proto-Oncogene Proteins
Promoter Regions, Genetic
Adenoma, Oxyphilic
A usually benign glandular tumor composed of oxyphil cells, large cells with small irregular nuclei and dense acidophilic granules due to the presence of abundant MITOCHONDRIA. Oxyphil cells, also known as oncocytes, are found in oncocytomas of the kidney, salivary glands, and endocrine glands. In the thyroid gland, oxyphil cells are known as Hurthle cells and Askanazy cells.
Carcinosarcoma
Neoplasms
Microsatellite Repeats
Adenocarcinoma, Scirrhous
Chromosomes, Human, Pair 3
Papillomavirus Infections
Multivariate Analysis
Carcinoma, Ehrlich Tumor
Mucin-1
Carbohydrate antigen elevated in patients with tumors of the breast, ovary, lung, and prostate as well as other disorders. The mucin is expressed normally by most glandular epithelia but shows particularly increased expression in the breast at lactation and in malignancy. It is thus an established serum marker for breast cancer.
Cell Movement
Transcription Factors
In Situ Hybridization
DNA-Binding Proteins
Teratoma
A true neoplasm composed of a number of different types of tissue, none of which is native to the area in which it occurs. It is composed of tissues that are derived from three germinal layers, the endoderm, mesoderm, and ectoderm. They are classified histologically as mature (benign) or immature (malignant). (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1642)
Cystadenocarcinoma, Papillary
Ampulla of Vater
Nuclear Proteins
Oligonucleotide Array Sequence Analysis
Neoplasms, Squamous Cell
Carcinoma, Skin Appendage
Common Bile Duct Neoplasms
RNA, Small Interfering
Small double-stranded, non-protein coding RNAs (21-31 nucleotides) involved in GENE SILENCING functions, especially RNA INTERFERENCE (RNAi). Endogenously, siRNAs are generated from dsRNAs (RNA, DOUBLE-STRANDED) by the same ribonuclease, Dicer, that generates miRNAs (MICRORNAS). The perfect match of the siRNAs' antisense strand to their target RNAs mediates RNAi by siRNA-guided RNA cleavage. siRNAs fall into different classes including trans-acting siRNA (tasiRNA), repeat-associated RNA (rasiRNA), small-scan RNA (scnRNA), and Piwi protein-interacting RNA (piRNA) and have different specific gene silencing functions.
Polymorphism, Single-Stranded Conformational
Variation in a population's DNA sequence that is detected by determining alterations in the conformation of denatured DNA fragments. Denatured DNA fragments are allowed to renature under conditions that prevent the formation of double-stranded DNA and allow secondary structure to form in single stranded fragments. These fragments are then run through polyacrylamide gels to detect variations in the secondary structure that is manifested as an alteration in migration through the gels.
Iodine Radioisotopes
Cell Differentiation
Cytological diagnosis of adenoid cystic carcinoma breast--a case report. (1/324)
The cytologic features of a case of adenoid cystic carcinoma of breast diagnosed on fine needle aspiration cytology (FNAC) in a 52 years old female are described. FNAC was carried out on outer quadrant of breast. The characteristic cytological features were numerous single to branching small round to Avoid cells at places forming microacini. Numerous pink hyaline globules of variable sizes were seen along with finger like projections containing basement membrane material. (+info)Failure patterns and factors affecting prognosis of salivary gland carcinoma: retrospective study. (2/324)
OBJECTIVES: To investigate the failure patterns and the prognostic factors following postoperative radiotherapy for salivary gland carcinoma. DESIGN: Retrospective study. SETTING: University teaching hospital, Hong Kong. PATIENTS: Fifty patients who had non-disseminated salivary gland carcinoma and who received primary treatment from 1984 through 1993. MAIN OUTCOME MEASURES: Demographic data, cancer T- and N-stages, histological type, site of origin, completeness of surgery, whether postoperative radiotherapy was given, and the clinical outcome. RESULTS: Two (4%) patients had been treated with radiotherapy alone, six (12%) had undergone radical resection alone, and 42 (84%) had been radically treated by using both modalities. The 5-year overall survival and relapse-free survival rates were 78.4% and 63.1%, respectively. The free from local failure and free from distant metastasis rates at 5 years were 77.2% and 72.8%, respectively. The N-stage was a significant prognostic factor. The site of the primary tumour, T-stage, completeness of surgery, and use of postoperative radiotherapy were not significant independent prognosticators; however, among the T-stage tumours, the b-substage carcinomas had significantly fewer local failures (P=0.040) and better survival rates (P=0.038) than the a-substage carcinomas. There were seven (14%) locoregional failures without distant metastasis, seven (14%) cases of distant metastasis without locoregional failures, and four (8%) locoregional failures preceding distant metastasis; isolated regional relapse was rare (1/50; 2%). All regional failures (5/50; 10%) occurred ipsilateral to the primary lesion. There were no deaths due to lymphoepithelioma-like carcinoma or acinic cell carcinoma. CONCLUSIONS: The N-stage is the main prognostic factor of overall survival, relapse- and metastasis-free recovery, and success of treatment for salivary gland carcinoma. Optimal locoregional treatment can help reduce distant metastasis, and the maximal use of postoperative radiotherapy may contribute to improved locoregional control. Elective ipsilateral neck radiotherapy is indicated for lymphoepithelioma-like carcinoma. (+info)Pulmonary epithelial-myoepithelial tumor of unproven malignant potential: report of a case and review of the literature. (3/324)
Epithelial-myoepithelial tumors of the lung are rare neoplasms whose biological behavior and clinical course still remain to be defined. A case of epithelial-myoepithelial tumor of the lung arising from bronchial mucosa-submucosa and occurring as a polypoid lesion of the upper left bronchus in a 47-year-old man is reported. The tumor did not infiltrate the cartilaginous wall of the bronchus and showed a biphasic histological appearance with a double layering of epithelial and myoepithelial cells. Myoepithelial spindle cells with eosinophilic cytoplasm were also observed. Mitotic figures were very rare and necrosis absent. Immunohistochemical study for epithelial and muscular markers confirmed the presence of a double-cell component in the tumor, namely epithelial and myoepithelial. The patient is alive and well, with no evidence of recurrent or metastatic disease 6 months after surgery. On the basis of the present case and the six previously reported cases, we suggest using the noncommittal term pulmonary epithelial-myoepithelial tumor of unproven malignant potential (PEMTUMP) for this type of neoplasm. In addition, we first introduce p63 as a novel marker for highlighting the myoepithelial cells of the respiratory tract and speculate on the role of these cells in the development of this unusual tumor. (+info)Novel DNA copy number losses in chromosome 12q12--q13 in adenoid cystic carcinoma. (4/324)
In order to find common genetic abnormalities that may identify loci of genes involved in the development of adenoid cystic carcinoma (ACC), we investigated DNA copy number changes in 24 of these tumors by comparative genomic hybridization (CGH). Our results indicate that unlike many carcinomas, ACCs have relatively few changes in DNA copy number overall. Twenty tumors had DNA copy number changes, which were mostly restricted to a few chromosomal arms. A frequent novel finding was the loss of DNA copy number in chromosome 12q (eight tumors, 33%) with the minimal common overlapping region at 12q12--q13. Deletion in this region has not been reported to be frequent in other types of cancer analyzed by CGH. In addition, deletions in 6q23-qter and 13q21--q22 and gains of chromosome 19 were observed in 25% to 38% of ACCs. Deletion of 19q, previously reported in a small series of ACC, was not identified in the current group of carcinomas. The current CGH results for chromosomes 12 and 19 were confirmed by microsatellite allelotyping. These results indicate that DNA copy number losses in 12q may be important in the oncogenesis of ACC and suggest that the 12q12--q13 region may harbor a new tumor-suppressor gene. (+info)Loss of heterozygosity at cylindromatosis gene locus, CYLD, in sporadic skin adnexal tumours. (5/324)
AIM: The gene for familial cylindromatosis (CYLD) has been localised to chromosome 16q, and has recently been cloned. Loss of heterozygosity (LOH) at 16q has also been demonstrated in sporadic cylindromas. The aim of this study was to investigate whether CYLD plays a role in the development of other skin appendage tumours. METHODS: A total of 55 cases of skin adnexal tumours, comprising 12 different types, and a control group of 14 squamous cell carcinomas (SCCs) and basal cell carcinomas (BCCs) were studied. Three microsatellites (D16S407 (16p), D16S304 (16q), and D16S308 (16q)) were analysed for LOH after microdissection from paraffin wax embedded sections using laser capture microdissection. RESULTS: In keeping with previous data, a proportion of cylindromas exhibited LOH at markers on 16q, but not at 16p. The skin adnexal tumours showing a similar pattern included apocrine hydrocystomas, eccrine spiradenomas, and sebaceous adenoma. One case of syringoma showed LOH at 16q, and a further case at 16p, but not 16q. One case of eccrine hydrocystoma showed loss at 16p, but not 16q. The remaining tumours were either negative or non-informative. All tumours in the control group were either negative or non-informative, except for a single case of BCC showing LOH at 16q. CONCLUSION: CYLD may be involved in the development of skin adnexal tumours other than cylindromas. (+info)Bronchial sleeve resection with complete preservation of the lung for carcinoma. (6/324)
Conservative sleeve resection with complete preservation of the lung parenchyma is very rarely applicable for the treatment of bronchial carcinomas. We used this surgical procedure in four patients with bronchial carcinoma in various sites of the central airway, and we obtained successful results. The pathological types were two squamous cell carcinomas and two low-grade malignant tumors (mucoepidermoid carcinoma and adenoid cystic carcinoma). If patients are properly selected, this operative procedure appears to be a safe and radical therapeutic option for the treatment of bronchial neoplasms arising from major bronchi. (+info)Radiologic-pathologic correlation of unusual lingual masses: Part II: benign and malignant tumors. (7/324)
Because the tongue is superficially located and the initial manifestation of most diseases occurring there is mucosal change, lingual lesions can be easily accessed and diagnosed without imaging analysis. Some lingual neoplasms, however, may manifest as a submucosal bulge and be located in a deep portion of the tongue, such as its base; their true characteristics and extent may be recognized only on cross-sectional images such as those obtained by CT or MRI. Some uncommon tongue neoplasms may have characteristic radiologic features, thus permitting quite specific radiologic diagnosis. Lipomas typically manifest at both CT and MR imaging as homogeneous nonenhancing lesions. Relative to subcutaneous fat they are isoattenuating on CT images, and all MR sequences show them as isointense. Due to the paramagnetic properties of melanin, metastases from melanotic melanoma usually demonstrate high signal intensity on T1-weighted MR images and low signal intensity on T2-weighted images. Although the radiologic findings for other submucosal neoplasms are nonspecific, CT and MR imaging can play an important role in the diagnostic work-up of these unusual tumors. Delineation of the extent of the tumor, and recognition and understanding of the spectrum of imaging and the pathologic features of these lesions, often help narrow the differential diagnosis. (+info)Defective laminin 5 processing in cylindroma cells. (8/324)
Cylindromas are benign skin tumors occurring as multiple nodules characteristically well circumscribed by an excess of basement membrane-like material. To determine the molecular defects leading to extracellular matrix accumulation, the ultrastructural, immunological, and biochemical properties of cylindroma tissue and isolated cells were analyzed. In cylindromas, hemidesmosomes are reduced in number, heterogeneous and immature compared to the normal dermal-epidermal junction. Expression of the alpha6beta4 integrin in tumor cells is weaker than in basal keratinocytes of the epidermis. Moreover, although in the epidermis alpha2beta1-integrin expression is restricted to the basal cell layer, it is found in all neoplastic cells within the nodules. Laminin 5 is present throughout the whole thickness of the basement membrane-like zone whereas laminin 10 is restricted to the interface adjacent to the tumor cells. Furthermore, laminin 5 is not properly processed and most of the alpha3A and gamma2 laminin chains remain as 165-kd and 155-kd polypeptides, respectively. Mature laminin 5 is thought to be necessary for correct hemidesmosome and basement membrane formation and its abnormal processing, as well as the low expression of alpha6beta4 integrins, could explain the lack of mature hemidesmosomes. Together, the results show that multiple molecular defects, including alteration of laminin 5 and its integrin receptors, contribute to structural aberrations of the basement membrane and associated structures in cylindromas. (+info)
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Rare Cancer News & Clinical Trials » PubMed - Adenoid Cystic Carcinoma
Adenoid Cystic Carcinoma
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Summary Report | CureHunter
Université de Montpellier - Genomic landscape of adenoid cystic carcinoma of the breast
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Most recent papers with the keyword hbxip | Read by QxMD
A comparison of the demographics, clinical features, and survival of patients with adenoid cystic carcinoma of major and minor...
Should we treat lung metastases from adenoid cystic carcinoma of the head and neck in asymptomatic patients? | Ear, Nose &...
Adenoid Cystic Carcinoma: Symptoms And Cause
A Study Of AL101 In Patients With Adenoid Cystic Carcinoma (ACC) Bearing Activating Notch Mutations | Canadian Cancer Trials -...
Cervical Lymph Node Metastasis in Adenoid Cystic Carcinoma of Oral Cavity and Oropharynx: A Collective International Review -...
Adenoid cystic carcinoma of the breast | Radiology Reference Article | Radiopaedia.org
外耳道腺样囊性癌1例
Adenoid cystic carcinoma of nasopharynx: a single-center retrospective study
Mass spectrometry-based proteome profile may be useful to differentiate adenoid cystic carcinoma from polymorphous...
Adenoid Cystic Carcinoma | Cancer.Net
The mutational landscape of adenoid cystic carcinoma<...
Cervical lymph node metastases in salivary gland adenoid cystic carcin | CMAR
Clinical Trial | Nelfinavir in Recurrent Adenoid Cystic Cancer of the Head and Neck
Papanicolaou check The World Wellness Firm WHO) classifies malignant tumors from the uterine cervix into three classes:...
Natural Cures for Adenoid Cystic Cancer
E-poster Presentation - ASN Events
Adenocarcinoma of the lacrimal gland: a case report | Journal of Medical Case Reports | Full Text
Genetic profiling of patients with adenoid cystic carcinoma of the Bartholins glands reveals potential new routes for targeted...
Adenoid Cystic Carcinoma, Minor Salivary Gland Cancer is back/Recurred Oh No Gabbymom04 - WhatNext.com
Bilateral Choroidal Metastasis as Initial Presentation of Parotid Gland Adenoid Cystic Carcinoma | Abstract
Brooke-Spiegler syndrome - Dermatology Advisor
Salivary Gland Cancer Research Update - Oral, Head, and Neck Cancer Center - EverydayHealth.com
Treatments for salivary gland cancer - Canadian Cancer Society
Tracheal resection and anastomosis for malignancy: surgical and functional outcome | International Journal of Current Research
Cetuximab and platinum-based chemoradio- or chemotherapy of patients with epidermal growth factor receptor expressing adenoid...
Adenoid Cystic Carcinoma Organization International =>...
Multiple familial trichoepithelioma - Wikipedia
Salivary Gland Cancer: Introduction | Cancer.Net
Radiation therapy for salivary gland cancer - Canadian Cancer Society
Salivary gland cancer patients son: My mom is the strongest person I
know | MD Anderson Cancer Center
Beastie Boys death: What is salivary gland cancer? - The Chart - CNN.com Blogs
Beastie Boys death: What is salivary gland cancer? - The Chart - CNN.com Blogs
Salivary gland cancer - Macmillan Cancer Support
On Trial | Hacking for Christ
CYLD GeneticTesting for Brooke-Spiegler Syndrome, Familial Cylindromatosis and Multiple Familial Trichoepitheliomas - PLOS...
PPT - Brooke-Spiegler Syndrome PowerPoint Presentation - ID:156085
salivary gland tumors with cribriform/canalicular growth pattern - Humpath.com - Human pathology
Malignant tracheal tumors
Meddygfa Victoria Surgery - Library - Health A-Z
NHS website
NHS website
Swineshead Medical Group - Library - Health A-Z
salivary gland cancer squamous cell carcinoma drug therapy 2000:2010[pubdate] *count=100 - BioMedLib™ search engine
Head and Neck Cancer - Bioprognos
Cervical adenoid basal carcinoma associated with invasive squamous cell carcinoma: A report of rare co-existence and review of...
Ceruminous adenocarcinoma - Wikipedia
Familial Cylindromatosis (Turban Tumor Syndrome): Symptoms, Diagnosis and Treatment - Symptoma
Carbon Ion Therapy
Antibody Review - Other Tumor Markers
Damned cancer returns, so here we go again, and lets talk about it | Offenburger.com
Cheeky Librarian: One more post about non-cancer websites
Cheeky Librarian: January 2013
Cylindroma of the Trachea | JAMA Otolaryngology-Head & Neck Surgery | The JAMA Network
RePub, Erasmus University Repository:
Multiple familial trichoepithelioma and familial cylindroma: One cause!
Salivary Gland Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] | HealthLink BC
Salivary Gland Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] | Cigna
Top Pituitary Gland Cancer Hospitals in Navi Mumbai | Credihealth
Ceruminous adenocarcinoma
... ceruminous adenoid cystic carcinoma (ACC), and ceruminous mucoepidermoid carcinoma. This tumor only affects the outer 1/3 to 1/ ... NOS Ceruminous adenoid cystic carcinoma Ceruminous mucoepidermoid carcinoma All of the tumors are infiltrative into the soft ... Aikawa, H.; Tomonari, K.; Okino, Y.; Hori, F.; Ueyama, T.; Suenaga, S.; Bundo, J.; Tsuji, K. (1997). "Adenoid cystic carcinoma ... The most common tumor type is ceruminous adenoid cystic carcinoma and ceruminous adenocarcinoma, NOS. Pain is the most common ...
Sialoblastoma
It is important that other tumors such as pleomorphic adenoma, basal cell adenoma, adenoid cystic carcinoma, and teratoma be ... Dardick, I.; Daley, T. D.; McComb, R. J. (2010). "Sialoblastoma in adults: Distinction from adenoid cystic carcinoma". Oral ...
Reinforcement
Goldman NC (1992). "Adenoid cystic carcinoma of the external auditory canal". Otolaryngology-Head and Neck Surgery. 106 (2): ...
Santosh G. Honavar
"Adenoid cystic carcinoma of the lacrimal gland: role of nuclear survivin (BIRC5) as a prognostic marker". Histopathology. 62 (6 ... "Primary adenoid cystic carcinoma: an extremely rare eyelid tumor". Ophthalmic Plast Reconstr Surg. 28 (2): e35-6. doi:10.1097/ ... Honavar SG (2018). "Sebaceous gland carcinoma: Can we do better?". Indian J Ophthalmol. 66 (9): 1235-1237. doi:10.4103/ijo.IJO_ ... Mulay K, White VA, Shah SJ, Honavar SG (2014). "Sebaceous carcinoma: clinicopathologic features and diagnostic role of ...
Laryngotracheal stenosis
Kokturk N, Demircan S, Kurul C, Turktas H (October 2004). "Tracheal adenoid cystic carcinoma masquerading asthma: a case report ...
Fast neutron therapy
Neutron radiotherapy for adenoid cystic carcinoma of minor salivary glands. International Journal of Radiation Oncology, ... Bull Cancer Radiother 83 (Suppl): 125-9s, 1996 See also the NCI Salivary Cancer Page Adenoid Cystic Carcinoma Neutron Radiation ... Fast neutron therapy has been applied successfully against salivary gland tumors.Adenoid cystic carcinomas have also been ... adenoid cystic carcinomas and certain types of brain tumors, especially high-grade gliomas When therapeutic energy X-rays (1 to ...
Deaths in July 2018
Gervase Markham, 40, British computer programmer (Mozilla), adenoid cystic carcinoma. Mateja Matejić, 94, Yugoslavian-born ...
Ceruminous gland
The malignant tumors include ceruminous adenocarcinoma, adenoid cystic carcinoma, and mucoepidermoid carcinoma. List of ...
Wendi Andriano
After many misdiagnoses, Joe was diagnosed with adenoid cystic carcinoma in 1998. At that time his illness had become terminal ...
Michele Serros
She was diagnosed with adenoid cystic carcinoma of the salivary gland in 2013. The cancer had metastasized and while she ...
Deaths in August 2012
Johnny Munkhammar, 37, Swedish politician, MP (2010-2012) and writer, adenoid cystic carcinoma. Johnny Pesky, 92, American ...
Super-enhancer
March 2016). "An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma". Nature Genetics. 48 (3 ...
Ceruminous adenocarcinoma
... ceruminous adenoid cystic carcinoma (ACC),[1][2] and ceruminous mucoepidermoid carcinoma. ... ceruminous adenoid cystic carcinoma (ACC),[1][2] ceruminous mucoepidermoid carcinoma. ... The specific features of each tumor type can help with the separation into adenoid cystic carcinoma or mucoepidermoid types.[3] ... Dong, F.; Gidley, P. W.; Ho, T.; Luna, M. A.; Ginsberg, L. E.; Sturgis, E. M. (2008). "Adenoid Cystic Carcinoma of the External ...
GABRB2
"Identification of differentially expressed genes in salivary adenoid cystic carcinoma cells associated with metastasis". ... GABRB2 was upregulated and hypomethylated in papillary thyroid carcinoma. The downregulation of GABRB2 enhanced the apoptotic ... GABRB2 was upregulated in adrenocortical carcinoma and salivary gland cancer, but downregulated in patients with colorectal ... 22 April 2014). "Identification of Unique miRNA Biomarkers in Colorectal Adenoma and Carcinoma Using Microarray: Evaluation of ...
Deaths in February 2019
Peter Tork, 77, American musician and actor (The Monkees), complications of adenoid cystic carcinoma. Lionel Upton, 94, ...
Gabriele Grunewald
Grunewald was diagnosed with adenoid cystic carcinoma, a rare type of cancer, in 2009. Due to tumors, her salivary gland was ...
Polymorphous low-grade adenocarcinoma
Microscopically, its histology can be confused with an adenoid cystic carcinoma and a pleomorphic adenoma. Polymorphous low- ...
Tracheal tumor
Among these, the most common are the squamous-cell carcinoma and the adenoid cystic carcinoma. Ferretti GR, Bithigoffer C, ...
Vijay Anand Reddy
Anand P Reddy, Vijay; Mulay, Kaustubh (28 June 2013). "Adenoid cystic carcinoma of the lacrimal gland: role of nuclear survivin ...
Gervase Markham (programmer)
Markham was a born-again Christian, and had been undergoing treatment for metastatic adenoid cystic carcinoma. He wrote about ...
Salivary gland tumour
Adenoid cystic carcinoma Polymorphous low-grade adenocarcinoma Epithelial-myoepithelial carcinoma Clear cell carcinoma, not ... an ancillary marker for adenoid cystic carcinoma". Mod. Pathol. 16 (12): 1224-31. doi:10.1097/01.MP.0000096046.42833.C7. PMID ... not otherwise specified Myoepithelial carcinoma Carcinoma ex pleomorphic adenoma Mammary analogue secretory carcinoma ... grade cribriform cystadenocarcinoma Mucinous adenocarcinoma Oncocytic carcinoma Salivary duct carcinoma Salivary duct carcinoma ...
ERBB3
1996). "Expression of c-erbB family gene products in adenoid cystic carcinoma of salivary glands: an immunohistochemical study ... Lee H, Maihle NJ (1998). "Isolation and characterization of four alternate c-erbB3 transcripts expressed in ovarian carcinoma- ... 1995). "High expression of the EGFR in fibroadenomas compared to breast carcinomas". Anticancer Res. 14 (5A): 1679-88. PMID ... 1995). "Prognostic significance of ERBB3 overexpression in oral squamous cell carcinoma". Cancer Lett. 95 (1-2): 79-83. doi: ...
Parotid gland
Adenoid cystic carcinoma is also a common malignant salivary gland lesion and has an incidence of 4-8%. This carcinoma tends to ... with the most common tumors being mucoepidermoid carcinoma and adenoid cystic carcinoma. Other malignant tumors of the parotid ... squamous cell carcinoma (arising from parenchyma of parotid gland), and undifferentiated carcinoma. Metastasis from other sites ... Mucoepidermoid carcinoma is a common malignant tumour of the salivary glands and has a low incidence of 4-13%. ...
Nancy Conz
On February 8, 2017, Conz died in Southampton, Massachusetts after a near 20 year battle with adenoid cystic carcinoma. She was ...
Orbit (anatomy)
... lymphoma or adenoid cystic carcinoma). Tumors (e.g. glioma and meningioma of the optic nerve) within the cone formed by the ...
Myoepithelial cell
Only rare cancers like adenoid cystic carcinomas contains myoepithelial cells as one of the malignant component. It can be ... Epithelial-myoepithelial carcinoma (of the salivary glands) - A low-grade malignant tumor composed of both neoplastic ... If malignant, this is also known as a Myoepithelial Carcinoma. Jules J. Berman (2009). Neoplasms: principles of development and ... A usually benign or exceedingly rare malignant tumor of the breast which mimics IDC but with cells resembling adenoid cysts. ...
Head and neck cancer
... adenoid cystic carcinomas, and mucoepidermoid carcinomas. Rarer still are melanomas and lymphomas of the upper aerodigestive ... Squamous cell carcinoma is most likely to appear in males over 40 years of age with a history of heavy alcohol use coupled with ... Squamous-cell carcinoma is a cancer of the squamous cell - a kind of epithelial cell found in both the skin and mucous ... Oropharyngeal squamous cell carcinomas (OSCC) begins in the oropharynx (throat), the middle part of the throat that includes ...
MMP15
2006). "[Analysis of differential expression genes related to different metastasis potential of adenoid cystic carcinoma using ...
Peter Tork
On March 3, 2009, Tork reported on his website that he had been diagnosed with adenoid cystic carcinoma, a rare, slow-growing ... his cancer experience on Facebook and encouraged his fans to support research efforts of the Adenoid Cystic Carcinoma Research ...
Carcinoid
Pancreatic ductal carcinoma. *cystic neoplasms: Serous microcystic adenoma. *Intraductal papillary mucinous neoplasm ... The term 'crypt cell carcinoma' has been used for them, and though perhaps more accurate than considering them carcinoids, has ... "carcinoma-like", to describe the unique feature of behaving like a benign tumor despite having a malignant appearance ... Adrenocortical adenoma/Adrenocortical carcinoma. *Hurthle cell. Other/multiple. *Neuroendocrine tumor *Carcinoid. *Adenoid ...
Lichen planus
Malignant: Acinic cell carcinoma. *Adenocarcinoma. *Adenoid cystic carcinoma. *Carcinoma ex pleomorphic adenoma ... Oral squamous cell carcinoma (SCC)[edit]. SCC can present as erythematous or white patches, ulcers, or exophytic masses. The ... Li TJ, Cui J (August 2013). "COX-2, MMP-7 expression in oral lichen planus and oral squamous cell carcinoma". Asian Pacific ... It has also been hypothesized that it is a precursor to squamous cell carcinoma of the esophagus.[12][33] ...
Carcinoma
M8170/3) Hepatocellular carcinoma, NOS. *(M8200/3) Adenoid cystic carcinoma. *(M8312/3) Renal cell carcinoma ... In some types of carcinomas, Stage 0 carcinoma has been used to describe carcinoma in situ, and occult carcinomas detectable ... Some carcinomas are named for their or the putative cell of origin, (e.g.hepatocellular carcinoma, renal cell carcinoma). ... Carcinoma In situ[edit]. The term carcinoma in situ (or CIS) is a term for cells that are significantly abnormal but not cancer ...
Aphthous stomatitis
Malignant: Acinic cell carcinoma. *Adenocarcinoma. *Adenoid cystic carcinoma. *Carcinoma ex pleomorphic adenoma ... Tissue biopsy is not usually required, unless to rule out other suspected conditions such as oral squamous cell carcinoma.[18] ...
Dentin hypersensitivity
Malignant: Acinic cell carcinoma. *Adenocarcinoma. *Adenoid cystic carcinoma. *Carcinoma ex pleomorphic adenoma ...
Somatostatinoma
Cystic general. *Cystadenoma/Cystadenocarcinoma. Mucinous. *Signet ring cell carcinoma *Krukenberg tumor. *Mucinous cystadenoma ... Adrenocortical adenoma/Adrenocortical carcinoma. *Hurthle cell. Other/multiple. *Neuroendocrine tumor *Carcinoid. *Adenoid ...
Orbit (anatomy)
... lymphoma or adenoid cystic carcinoma).[10]. Tumors (e.g. glioma and meningioma of the optic nerve) within the cone formed by ...
Category:Infobox medical condition (new)
Adenoid cystic carcinoma. *Adenoid hypertrophy. *Adenoiditis. *Adenoma sebaceum. *Adenomatoid tumor. *Adenomyoma. *Adenomyosis ...
Hepatocellular adenoma
Pancreatic ductal carcinoma. *cystic neoplasms: Serous microcystic adenoma. *Intraductal papillary mucinous neoplasm ... Adrenocortical adenoma/Adrenocortical carcinoma. *Hurthle cell. Other/multiple. *Neuroendocrine tumor *Carcinoid. *Adenoid ...
Cutaneous horn
Merkel cell carcinoma. *Microcystic adnexal carcinoma. *Mucinous carcinoma. *Primary cutaneous adenoid cystic carcinoma ... Solivan, GA; Smith, KJ; James, WD (1990). "squamous cell carcinoma". Journal of the American Academy of Dermatology. 23 (5 Pt 2 ... The incidence of squamous cell carcinoma increases to 37% when the cutaneous horn is present on the penis.[3] Tenderness at the ... Malignancy is present in up to 20% of cases, with squamous cell carcinoma being the most common type. ...
印戒细胞癌 - 维基百科,自由的百科全
Adenoid cystic carcinoma(英语:Adenoid cystic carcinoma). *Oncocytoma(英语:Oncocytoma) ... Medullary carcinoma(英语:Medullary carcinoma). *Medullary carcinoma of the breast(英语:Medullary carcinoma of the breast) ... Lobular carcinoma(英语:Lobular carcinoma). *Lobular carcinoma in situ(英语:Lobular carcinoma in situ) ... Ductal carcinoma(英语:Ductal carcinoma). *Mammary ductal carcinoma(英语:Mammary ductal carcinoma) ...
Skin cancer
Merkel cell carcinoma. *Microcystic adnexal carcinoma. *Mucinous carcinoma. *Primary cutaneous adenoid cystic carcinoma ... "Squamous cell carcinoma (epidermoid carcinoma) - skin". Atlas of Pathology (3rd ed.). Universitatii St., Iasi, Romania. ... The most common form of skin cancer is basal-cell carcinoma, followed by squamous cell carcinoma. Unlike for other cancers, ... whereas it might be inadequate for invasive nodular basal-cell carcinoma or invasive squamous-cell carcinoma.[citation needed] ...
Black hairy tongue
Malignant: Acinic cell carcinoma. *Adenocarcinoma. *Adenoid cystic carcinoma. *Carcinoma ex pleomorphic adenoma ...
Mouth ulcer
Malignant: Acinic cell carcinoma. *Adenocarcinoma. *Adenoid cystic carcinoma. *Carcinoma ex pleomorphic adenoma ... The most common type of oral cancer is squamous cell carcinoma. The main causes are long-term smoking and alcohol consumption ( ... Malignancies in the mouth are usually carcinomas, but lymphomas, sarcomas and others may also be possible. Either the tumor ...
Asbestosis
The black arrows point to ferrugionous bodies that are located at the periphery of a focus of non-small cell lung carcinoma, ... Adenoid hypertrophy. Peritonsillar abscess. Neck. pharynx. Pharyngitis Strep throat. Laryngopharyngeal reflux (LPR). ... Cystic fibrosis. unspecified. Bronchitis. Bronchiolitis Bronchiolitis obliterans. Diffuse panbronchiolitis. Interstitial/. ... "Asbestos content of lung tissue and carcinoma of the lung: a clinicopathologic correlation and mineral fiber analysis of 234 ...
Linitis plastica
Pancreatic ductal carcinoma. *cystic neoplasms: Serous microcystic adenoma. *Intraductal papillary mucinous neoplasm ... Microscopic appearance is signet ring cell carcinoma, which is tumor cells with mucin droplet that displaces the nucleus to one ... particularly breast and lung carcinoma.[1] It is not associated with H. pylori infection or chronic gastritis. The risk factors ... Adrenocortical adenoma/Adrenocortical carcinoma. *Hurthle cell. Other/multiple. *Neuroendocrine tumor *Carcinoid. *Adenoid ...
ಬಾಯಿಯ ಕ್ಯಾನ್ಸರ್ - ವಿಕಿಪೀಡಿಯ
malignant epithelial tumors (Acinic cell carcinoma, Mucoepidermoid carcinoma, Adenoid cystic carcinoma, Salivary duct carcinoma ... Epithelial-myoepithelial carcinoma, Polymorphous low-grade adenocarcinoma, Hyalinizing clear cell carcinoma) ...
Gingivitis
Malignant: Acinic cell carcinoma. *Adenocarcinoma. *Adenoid cystic carcinoma. *Carcinoma ex pleomorphic adenoma ...
Herpes simplex
Malignant: Acinic cell carcinoma. *Adenocarcinoma. *Adenoid cystic carcinoma. *Carcinoma ex pleomorphic adenoma ...
Eagle syndrome
Malignant: Acinic cell carcinoma. *Adenocarcinoma. *Adenoid cystic carcinoma. *Carcinoma ex pleomorphic adenoma ...
زونا - ویکیپدیا، دانشنامهٔ آزاد
Malignant: Acinic cell carcinoma. *Adenocarcinoma. *Adenoid cystic carcinoma. *Carcinoma ex pleomorphic adenoma ...
Behçet's disease
Malignant: Acinic cell carcinoma. *Adenocarcinoma. *Adenoid cystic carcinoma. *Carcinoma ex pleomorphic adenoma ...
Actinic keratosis
Merkel cell carcinoma. *Microcystic adnexal carcinoma. *Mucinous carcinoma. *Primary cutaneous adenoid cystic carcinoma ... Moy, RL (Jan 2000). "Clinical presentation of actinic keratoses and squamous cell carcinoma". Journal of the American Academy ... Salasche, SJ (January 2000). "Epidemiology of actinic keratoses and squamous cell carcinoma". Journal of the American Academy ... Salasche, SJ (January 2000). "Epidemiology of actinic keratoses and squamous cell carcinoma". Journal of the American Academy ...
Wart
Merkel cell carcinoma. *Microcystic adnexal carcinoma. *Mucinous carcinoma. *Primary cutaneous adenoid cystic carcinoma ...
Multiple endocrine neoplasia
Cystic general. *Cystadenoma/Cystadenocarcinoma. Mucinous. *Signet ring cell carcinoma *Krukenberg tumor. *Mucinous cystadenoma ... Sipple JH (1961). "The association of pheochromocytoma with carcinoma of the thyroid gland". Am. J. Med. 31: 163-6. doi:10.1016 ... In 1959 Hazard et al. described medullary (solid) thyroid carcinoma. In 1961 Sipple described a combination of a ... Micrograph of a medullary thyroid carcinoma, as may be seen in MEN 2A and MEN 2B. H&E stain. ...
Warthin's tumor
Adenoid cystic carcinoma. *Salivary duct carcinoma. *Epithelial-myoepithelial carcinoma. *Polymorphous low-grade adenocarcinoma ... There are cystic spaces surrounded by two uniform rows of epithelial cells with centrally placed pyknotic nuclei. The cystic ... Warthin's tumor, also known as papillary cystadenoma lymphomatosum, is a benign cystic tumor of the salivary glands containing ...
William H. Welch
Deaths from adenoid cystic carcinoma. *Johns Hopkins Bloomberg School of Public Health ...
Prolactinoma
Cystic, mucinous,. and serous. Cystic general. *Cystadenoma/Cystadenocarcinoma. Mucinous. *Signet ring cell carcinoma * ... Adrenocortical adenoma/Adrenocortical carcinoma. *Hürthle cell. Other/multiple. *Neuroendocrine tumor *Carcinoid. *Adenoid ...
Adenoid cystic carcinoma | Define Adenoid cystic carcinoma at Dictionary.com
Adenoid Cystic Carcinoma: Statistics | Cancer.Net
Primary cutaneous adenoid cystic carcinoma - Wikipedia
Primary cutaneous adenoid cystic carcinoma is a cutaneous condition characterized by a tumor that usually presents on the chest ... Primary cutaneous adenoid cystic carcinomas have been misinterpreted as metastatic lesions. It was characterized in 1975. ... "Primary cutaneous adenoid cystic carcinoma". J. Am. Acad. Dermatol. 58 (4): 636-41. doi:10.1016/j.jaad.2007.12.005. PMID ... Aggressive digital papillary adenocarcinoma Mucinous carcinoma Skin lesion James, William D.; Berger, Timothy G.; et al. (2006 ...
Sinonasal adenoid cystic carcinoma - Sanghvi - 2013 - The Laryngoscope - Wiley Online Library
S Ali, J C-L Yeo, T Magos, M Dickson, E Junor, Clinical outcomes of adenoid cystic carcinoma of the head and neck: a single ... Aykut A. Unsal, Sei Y. Chung, Albert H. Zhou, Soly Baredes, Jean Anderson Eloy, Sinonasal adenoid cystic carcinoma: a ... Sinonasal adenoid cystic carcinoma (SNACC) is a rare malignancy that most commonly arises in the maxillary sinus. ... Anniken Sandvik, Tor Audun Klingen, Sverre Langård, Sinonasal adenoid cystic carcinoma following formaldehyde exposure in the ...
JCI -
Genetic hallmarks of recurrent/metastatic adenoid cystic carcinoma
Search of: 'Adenoid cystic carcinoma' - Modify Search - ClinicalTrials.gov
Adenoid Cystic Carcinoma: Risk Factors | Cancer.Net
Search of: Adenoid Cystic Carcinoma - Results on Map - ClinicalTrials.gov
Hints: Click on a [map] link to show a map of that region. Click on a [studies] link to search within your current results for studies in that region. Use the back button to return to this list and try another region. Studies with no locations are not included in the counts or on the map. Studies with multiple locations are included in each region containing locations ...
Dovitinib in Adenoid Cystic Carcinoma - Full Text View - ClinicalTrials.gov
Carcinoma. Carcinoma, Adenoid Cystic. Neoplasms, Glandular and Epithelial. Neoplasms by Histologic Type. Neoplasms. ... MedlinePlus related topics: Adenoids Genetic and Rare Diseases Information Center resources: Adenoid Cystic Carcinoma ... Dovitinib in Adenoid Cystic Carcinoma. The safety and scientific validity of this study is the responsibility of the study ... The purpose of this phase II study of TKI258 (Dovitinib) in adenoid cystic carcinoma is to evaluate the efficacy of TKI258 ( ...
Adenoid Cystic Carcinoma Organization International - American Association for Cancer Research (AACR)
Adenoid Cystic Carcinoma Organization International. November 13, 2019 by Weiden Hammer Adenoid Cystic Carcinoma Organization ... a directory of doctors who treat adenoid cystic carcinoma, and information about clinical trials. ... International provides information about adenoid cystic carcinoma, a rare head and neck cancer, to people affected by the ...
American Urological Association - Basal Cell Carcinoma (Adenoid Cystic Carcinoma)
Adenoid cystic carcinoma consists of infiltrative nests with prominent cribriform architecture (image C) & (image D). ... Home Education AUAUniversity Education Products & Resources Pathology for Urologists Prostate Other Uncommon Carcinomas Basal ... Cell Carcinoma (Adenoid Cystic Carcinoma) Basal Cell Carcinoma (Adenoid Cystic Carcinoma). Image A. ... Basal cell carcinoma consists of variably sized solid nests, cords, or trabeculae with peripheral palisading of cells (image A) ...
Histopathologic and Cytogenetic Features of Pulmonary Adenoid Cystic Carcinoma
... J Thorac Oncol. 2015 Nov;10(11):1570-5. doi: ... Introduction: A significant portion of adenoid cystic carcinoma (ACC) cases are characterized by a t(6;9)(q22-23;p23-24) ... FISH studies performed on other histologic subtypes of lung cancer (10 squamous cell carcinomas, 10 adenocarcinomas, and 10 ... small-cell carcinomas) failed to show MYB rearrangement. There was no significant difference in MYB rearrangement status with ...
Salivary Gland Adenoid Cystic Carcinoma. | GreenMedInfo | Disease
This topic contains 3 study abstracts on Salivary Gland Adenoid Cystic Carcinoma. indicating that the following substances may ... 6 Abstracts with Salivary Gland Adenoid Cystic Carcinoma. Research. Filter by Study Type. Human: Case Report. ... Diseases : Cancer Metastasis, Salivary Gland Adenoid Cystic Carcinoma., Salivary Gland Diseases. Pharmacological Actions : Anti ... Diseases : Cancer Metastasis, Salivary Gland Adenoid Cystic Carcinoma., Salivary Gland Diseases. Pharmacological Actions : Anti ...
Adenoid Cystic Carcinoma - The Oral Cancer Foundation
Adenoid Cystic Carcinomaadmin2018-06-05T15:08:10-08:00 What is Adenoid cystic carcinoma?. Adenoid cystic carcinoma (ACC) is an ... Fordice, J., Kershaw, C., el-Naggar, A., and Goepfert, H. (1999). Adenoid cystic carcinoma of the head and neck. Predictors of ... A wide age range has been reported for adenoid cystic carcinoma, including cases in the pediatric age group. Most individuals ... Spiers, A., Esseltine, D., Ruckdeschel, J., Davies, J., and Horton, J. (1996). Metastatic adenoid cystic carcinoma of salivary ...
Adenoid Cystic Carcinoma - The Oral Cancer Foundation
What is Adenoid cystic carcinoma?. Adenoid cystic carcinoma (ACC) is an uncommon form of malignant neoplasm that arises within ... Fordice, J., Kershaw, C., el-Naggar, A., and Goepfert, H. (1999). Adenoid cystic carcinoma of the head and neck. Predictors of ... A wide age range has been reported for adenoid cystic carcinoma, including cases in the pediatric age group. Most individuals ... Spiers, A., Esseltine, D., Ruckdeschel, J., Davies, J., and Horton, J. (1996). Metastatic adenoid cystic carcinoma of salivary ...
Mutation signature of adenoid cystic carcinoma: evidence for transcriptional and epigenetic reprogramming. - PubMed - NCBI
Adenoid cystic carcinoma (ACC), a relatively rare malignancy usually of salivary gland origin, has a signature v-myb avian ... Mutation signature of adenoid cystic carcinoma: evidence for transcriptional and epigenetic reprogramming.. Frierson HF Jr1, ... Mutation signature of adenoid cystic carcinoma: evidence for transcriptional and epigenetic reprogramming ... The neoplastic transformation of normal salivary gland (upper histologic figure) to adenoid cystic carcinoma (lower histologic ...
Adenoid Cystic Carcinoma of Distal Trachea: a Case Report
... and only ten percent of them are adenoid cystic carcinomas. Eighty percent of all tracheal tumors are malignant.... ... Adenoid Cystic Carcinoma of Distal Trachea: a Case Report. Željko Djaković orcid.org/0000-0002-7840-7519 ; Jordanovac ... "Adenoid Cystic Carcinoma of Distal Trachea: a Case Report." Acta clinica Croatica, vol. 58., br. 4., 2019, str. 777-779. https ... 2019). Adenoid Cystic Carcinoma of Distal Trachea: a Case Report, Acta clinica Croatica, 58.(4.), str. 777-779. Preuzeto s: ...
Stage IVC Oral Cavity Adenoid Cystic Carcinoma - DrugBank
This project is supported by the Canadian Institutes of Health Research (award #111062), Alberta Innovates - Health Solutions, and by The Metabolomics Innovation Centre (TMIC), a nationally-funded research and core facility that supports a wide range of cutting-edge metabolomic studies. TMIC is funded by Genome Alberta, Genome British Columbia, and Genome Canada, a not-for-profit organization that is leading Canadas national genomics strategy with funding from the federal government. Maintenance, support, and commercial licensing is provided by OMx Personal Health Analytics, Inc. Designed by Educe Design & Innovation Inc. ...
BRD4 inhibition suppresses cell growth, migration and invasion of salivary adenoid cystic carcinoma
Salivary adenoid cystic carcinoma (SACC) is a highly malignant carcinoma that most often arises from the secretory epithelial ... Perineural invasion in adenoid cystic carcinoma of the salivary glands: a valid prognostic indicator? Oral Oncol. 2009;45(11): ... 5. Wu HM, Ren GX, Wang LZ, Zhang CY, Chen WT, Guo W. Expression of podoplanin in salivary gland adenoid cystic carcinoma and ... Adenoid cystic salivary gland carcinoma: a histopathologic review of treatment failure patterns. Cancer. 1986;57(3):519-24. [ ...
Adenoid Cystic Carcinoma of the Head and Neck: Epidemiology and Predictors of Prognosis
The biologic behavior of the adenoid cystic carcinoma (ACC) and the factors predicting outcome for these tumors are still ... "Adenoid Cystic Carcinoma of the Head and Neck: Epidemiology and Predictors of Prognosis" written by Daniel Monteiro, João Lino ... A Study on 18 Cases of Parotid Adenoid Cystic Carcinoma. Practica Oto-Rhino-Laryngologica, 2017. DOI:10.5631/jibirin.110.475 ... Adenoid cystic carcinoma of head and neck. A 5-year retrospective study: Experience in a single third-level reference center ...
Adenoid Cystic Carcinoma Invade the Tracheal Prominence: A Case Report and Literature Review
Tracheal adenoid cystic carcinoma that invades the tracheal prominence is a relatively rare tumor among thoracic diseases. ... Objective: To explore the epidemiology, diagnosis, treatment and future development of tracheal adenoid cystic carcinoma (TACC ... a case of tracheal adenoid cystic carcinoma with asymptomatic invasion of the tracheal prominence was reported. The clinical ... Adenoid cystic carcinoma (ACC) refers to a salivary gland neoplasm. ...
Adenoid cystic carcinoma pathology | DermNet NZ
Adenocystic carcinoma. Authoritative facts from DermNet New Zealand. ... Adenoid cystic carcinoma typically arises within salivary glands. Primary cutaneous adenoid cystic carcinomaand adenoid cystic ... Histology of adenoid cystic carcinoma. In primary cutaneous adenoid cystic carcinoma, the tumour involves the dermis and may ... Special studies of adenoid cystic carcinoma. Adenoid cystic carcinoma is typically a morphologic diagnosis. The basement ...
Racing despite metastatic adenoid cystic carcinoma, a rare head and neck
cancer | MD Anderson Cancer Center
Jessica Garcia was worried that a metastatic adenoid cystic carcinoma diagnosis would end her professional outrigger canoeing ... Jessica Garcia was worried that a metastatic adenoid cystic carcinoma diagnosis would end her professional outrigger canoeing ... An unexpected adenoid cystic carcinoma diagnosis. My cancer journey began in 2007, when I discovered a tiny bump behind my left ... My adenoid cystic carcinoma recurrence. I continued to show no evidence of disease until 2013. During a follow-up appointment, ...
Rare Cancer Support Forum • View forum - Adenoid Cystic Carcinoma
Frontiers | A Comparative Study of Primary Adenoid Cystic and Mucoepidermoid Carcinoma of Lung | Oncology
... and pulmonary adenoid cystic carcinoma (PACC) are the two major types of primary salivary gland-type (PSGT) lung cancers. The ... and pulmonary adenoid cystic carcinoma (PACC) are the two major types of primary salivary gland-type (PSGT) lung cancers. The ... Keywords: pulmonary adenoid cystic carcinoma, pulmonary mucoepidermoid carcinoma, salivary gland tumor, primary salivary gland- ... Background: Pulmonary mucoepidermoid carcinoma (PMEC) and pulmonary adenoid cystic carcinoma (PACC) are the two major types of ...
https://www.thefreelibrary.com/Ceruminous+gland+adenoid+cystic+carcinoma+with+contralateral...-a082470789
Ceruminous gland adenoid cystic carcinoma with contralateral metastasis to the brain. by Archives of Pathology & Laboratory ... cystic+carcinoma+with+contralateral...-a082470789. *APA style: Ceruminous gland adenoid cystic carcinoma with contralateral ... carcinoma+with+contralateral...-a082470789,/a,. Citations: *MLA style: "Ceruminous gland adenoid cystic carcinoma with ... carcinoma+with+contralateral...-a082470789. *Chicago style: The Free Library. S.v. Ceruminous gland adenoid cystic carcinoma ...
Progressive genetic alterations of adenoid cystic carcinoma with high-grade transformation. - Free Online Library
by Archives of Pathology & Laboratory Medicine; Health, general Cancer Analysis Genetic aspects Carcinoma Cytogenetics DNA ... Progressive genetic alterations of adenoid cystic carcinoma with high-grade transformation. ... cystic+carcinoma+with...-a0330499522. *APA style: Progressive genetic alterations of adenoid cystic carcinoma with high-grade ... 28.) Ide F, Mishima K, Saito I. Small foci of high-grade carcinoma cells in adenoid cystic carcinoma represent an incipient ...
Adenoid Cystic Carcinoma
- Cylindroma
Summary Report | CureHunter
Carcinoma characterized by bands or cylinders of hyalinized or mucinous stroma separating or surrounded by nests or cords of ... Carcinomas, Adenocystic; Carcinomas, Adenoid Cystic; Cylindromas; Cystic Carcinoma, Adenoid; Cystic Carcinomas, Adenoid ... Cylindroma; Carcinoma, Adenoid Cystic; Adenocystic Carcinoma; Adenocystic Carcinomas; Adenoid Cystic Carcinomas; Carcinoma, ... Adenoid Cystic Carcinoma (Cylindroma). Subscribe to New Research on Adenoid Cystic Carcinoma ...
Chidamide Combined With Cisplatin in Head and Neck Adenoid Cystic Carcinoma (HNACC) - Full Text View - ClinicalTrials.gov
Carcinoma. Carcinoma, Adenoid Cystic. Neoplasms, Glandular and Epithelial. Neoplasms by Histologic Type. Neoplasms. ... Chidamide Combined With Cisplatin in Head and Neck Adenoid Cystic Carcinoma (HNACC). The safety and scientific validity of this ... Adenoid cystic carcinomas (ACCs) constitute of 1% of head and neck cancers. This type of tumor grows slowly with a high ... And a phase I study has showed that one of three patients with submandibular adenoid cystic carcinoma achieved a partial ...
Annual sporting clays tournament supports adenoid cystic carcinoma (ACC)
research at MD Anderson | MD Anderson Cancer Center
In his honor, the family established the Ryan W. Smith Endowed Fund for Adenoid Cystic Carcinoma Research at MD Anderson. ... as well as his courageous fight with stage IV adenoid cystic carcinoma (ACC), a rare cancer, when he was only 26 and newly ... The family soon established the Ryan W. Smith Endowed Fund for Adenoid Cystic Carcinoma Research to fund research and help ... Annual sporting clays tournament supports adenoid cystic carcinoma (ACC) research at MD Anderson ...
Mixed tumorPolymorphous low-grade adenAbstractAdenocarcinomaTumorsCutaneous adenoid cystic caMetastatic adenoidPathologyCylindromaPatients with adenoid cystic caAdCCDiagnosisMalignancyPrognosisSACCCancerNeckCribriformCases of adenoid cystic caMucoepidermoid carcinomaMajor and minor saliTreat adenoid cystic caTracheaNeoplasmsEpithelialClinicopathologicSubmandibularLacrimal glandImmunohistochemistryBasal Cell CarcTrachealMisinterpreted as metastaticInhibitionParotidPrimaryTumourBasaloid squamous carcinomaHuman salivaryClinical trialsRadiotherapyPleomorphicSquamous cell carcinomasArising in salivary glandsUncommonPulmonary adenoidRecurrenceMetastasesNeoplasm
Mixed tumor1
- In the salivary glands these include benign mixed tumor, mucoepidermoid carcinoma and polymorphous low-grade adenocarcinoma (PLGA). (oralcancerfoundation.org)
Polymorphous low-grade aden2
- Penner CR, Folpe AL, Budnick SD (2002) C-kit expression distinguishes salivary gland adenoid cystic carcinoma from polymorphous low-grade adenocarcinoma. (springer.com)
- It is the third most common malignant salivary gland tumor overall (after mucoepidermoid carcinoma and polymorphous low grade adenocarcinoma). (sinustumor.org)
Abstract1
- ABSTRACT: Objective: To review the records of cases of Bartholin's Gland Carcinoma referred to the Queensland Centre for Gynaecological Cancer (QCGC) between mid 1993 and mid 2012. (scirp.org)
Adenocarcinoma8
- Aggressive digital papillary adenocarcinoma Mucinous carcinoma Skin lesion James, William D. (wikipedia.org)
- 12,17) Histologic patterns of the transformed areas range from a cribriform high-grade adenocarcinoma to solid carcinoma with squamoid features. (thefreelibrary.com)
- Of the malignant epithelial lacrimal tumors 20% are pleomorphic adenocarcinoma, 10% are primary adenocarcinoma, and 5% are mucoepidermoid carcinoma. (aao.org)
- Adenoid cystic carcinomas are a rare histological subtype of adenocarcinoma. (radiopaedia.org)
- Mass spectrometry-based proteome profile may be useful to differentiate adenoid cystic carcinoma from polymorphous adenocarcinoma of salivary glands. (bioportfolio.com)
- Carcinoma ex-pleomorphic adenocarcinoma is an aggressive tumour that starts out as a non-cancerous mixed tumour. (cancer.ca)
- The most common tumor type is ceruminous adenoid cystic carcinoma and ceruminous adenocarcinoma, NOS. (wikipedia.org)
- The tumors are separated into three main histologic or microscopic types: Ceruminous adenocarcinoma, NOS Ceruminous adenoid cystic carcinoma Ceruminous mucoepidermoid carcinoma All of the tumors are infiltrative into the soft tissue, benign ceruminous glands, and/or bone. (wikipedia.org)
Tumors15
- Unlike most carcinomas, most patients with ACC survive for 5 years, only to have tumors recur and progress. (oralcancerfoundation.org)
- Primary malignant tumors of the trachea are very rare with the incidence of less than two per million people per year, and only ten percent of them are adenoid cystic carcinomas. (srce.hr)
- Salivary adenoid cystic carcinoma (SACC) is a highly malignant carcinoma that most often arises from the secretory epithelial cells of salivary glands [ 1 ] and comprises approximately 10% of all salivary tumors [ 2 ]. (scielo.cl)
- However, WHO classification of PSGT is non-specific and can include any tumor found in the salivary glands, cases of epithelial myoepithelial carcinoma, clear cell carcinoma, acinic tumors, mixed carcinoma, and carcinoma ex pleomorphic adenoma have been reported so far ( 4 - 9 ). (frontiersin.org)
- The outcome of a diagnosis of adenoid cystic carcinoma is somewhat different than that of other salivary and secretory gland tumors. (practicalpainmanagement.com)
- Of the malignant epithelial lacrimal gland tumors, about 60% are adenoid cystic carcinomas, and these most often involve the orbital lobe of the lacrimal gland. (aao.org)
- Adenoid cystic carcinoma of the salivary gland (SACC) is a rare malignant tumors of the head and neck region, but it is one of the most common malignant tumors that are prone to perineural invasion (PNI) of the head and neck. (frontiersin.org)
- The majority of tracheal tumors in adults are malignant and the most common ones are squamous cell carcinoma and adenoid cystic carcinoma (cylindroma). (springer.com)
- MYB expression and translocation in adenoid cystic carcinomas and other salivary gland tumors with clinicopathologic correlation. (semanticscholar.org)
- Activating NOTCH1 point mutations were also identified in other solid tumors, including adenoid cystic carcinoma (ACC). (aacrjournals.org)
- To assess the frequency of nodal involvement and its prognostic value in malignant tumors of the paranasal sinuses, particularly in maxillary sinus squamous cell carcinoma. (readbyqxmd.com)
- Adenoid cystic carcinoma (ACC) is among the most lethal salivary gland tumors, with no treatments for metastatic disease that prolong survival. (aacrjournals.org)
- Phase II trial of dasatinib for recurrent or metastatic c-KIT expressing adenoid cystic carcinoma and for nonadenoid cystic malignant salivary tumors. (uchicago.edu)
- Adenoid cystic carcinoma (ACC) is among the most common malignant salivary gland tumors. (biomedcentral.com)
- Staging of nasal cavity and paranasal sinus carcinomas is not as well established as for other head and neck tumors. (medscape.com)
Cutaneous adenoid cystic ca6
- Primary cutaneous adenoid cystic carcinoma is a cutaneous condition characterized by a tumor that usually presents on the chest, scalp, or vulva of middle- to older-aged persons. (wikipedia.org)
- Primary cutaneous adenoid cystic carcinoma and adenoid cystic carcinoma of the breast are rare but well recognized. (dermnetnz.org)
- In primary cutaneous adenoid cystic carcinoma, the tumour involves the dermis and may invade the subcutis (figure 1). (dermnetnz.org)
- Primary cutaneous adenoid cystic carcinoma: a clinicopathologic and immunohistochemical study of 27 cases," American Journal of Surgical Pathology , vol. 37, no. 10, pp. 1603-1611, 2013. (hindawi.com)
- J. Barnes and C. Garcia, "Primary cutaneous adenoid cystic carcinoma: a case report and review of the literature," Cutis , vol. 81, no. 3, pp. 243-246, 2008. (hindawi.com)
- C. Cacchi, S. Persechino, L. Fidanza, and A. Bartolazzi, "A primary cutaneous adenoid-cystic carcinoma in a young woman. (hindawi.com)
Metastatic adenoid8
- Metastatic adenoid cystic carcinoma of salivary glands: Case reports and review of the literature, Cancer Control 3, 336-342. (oralcancerfoundation.org)
- I've also had stereotactic radiation therapy and cryoablation, and taken immunotherapy and targeted therapy drugs to treat my metastatic adenoid cystic carcinoma, a rare type of head and neck cancer . (mdanderson.org)
- The brain lesion was subsequently biopsied and diagnosed as metastatic adenoid cystic carcinoma. (thefreelibrary.com)
- BUSINESS WIRE )--Ayala Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company dedicated to developing targeted cancer therapies for people living with cancer, today announced preliminary results from its ongoing Phase 2 ACCURACY study of lead investigational new drug candidate, AL101, in patients with recurrent/metastatic adenoid cystic carcinoma (ACC) with progressing disease and Notch activating mutations. (businesswire.com)
- In a single-center phase II study reported in the Journal of Clinical Oncology , Tchekmedyian et al found that the multitargeted tyrosine kinase inhibitor lenvatinib was active in progressive recurrent or metastatic adenoid cystic carcinoma. (ascopost.com)
- In the study, 32 evaluable patients at Memorial Sloan Kettering Cancer Center with recurrent or metastatic adenoid cystic carcinoma of any primary site and radiographic or symptomatic progression were treated with lenvatinib 24 mg orally per day. (ascopost.com)
- The investigators concluded, "This trial met the prespecified overall response rate primary endpoint, demonstrating antitumor activity with lenvatinib in [patients with recurrent or metastatic adenoid cystic carcinoma]. (ascopost.com)
- TARP expression was analyzed in 50 primary SACCs, 13 specimens of metastatic adenoid cystic carcinoma of salivary gland origin, and 20 noncancerous tissues around SACC via immunohistochemistry. (ovid.com)
Pathology4
- Pathology revealed the adenoid cystic carcinoma of the tracheal carina. (scirp.org)
- Unfortunately, after my surgery, pathology results showed my tumor was actually adenoid cystic carcinoma. (mdanderson.org)
- T. Terada, "Pigmented adenoid cystic carcinoma of the ear skin arising from the epidermis: a case report with immunohistochemical studies," International Journal of Clinical and Experimental Pathology , vol. 5, no. 3, pp. 254-259, 2012. (hindawi.com)
- Adenoid Cystic Carcinoma of the Oral Cavity: Radiology-Pathology Correlation. (uchicago.edu)
Cylindroma3
- Cylindroma - These tumours exhibit a typical "jigsaw puzzle" architecture rather than the irregular cribriform and tubular architecture of adenoid cystic carcinoma. (dermnetnz.org)
- Conley J, Dingman DL (1974) Adenoid cystic carcinoma in the head and neck (cylindroma). (springer.com)
- Adenoid cystic carcinoma also known as cylindroma is very rare and constitutes 1% of major and minor salivary glands malignancies. (longdom.org)
Patients with adenoid cystic ca3
- Collectively, these results suggest that patients with adenoid cystic carcinoma might benefit from therapy with a BH3-mimetic small molecule. (sigmaaldrich.com)
- analyzed the data of 507 patients with adenoid cystic carcinoma, and suggested that the positive edge is related to the worst outcome, while the negative edge and the near edge are related to the improved result, but not the distance of the tumor ( 9 ). (frontiersin.org)
- Eighty-two patients with adenoid cystic carcinoma treated by a radical course of radiotherapy are reviewed. (openrepository.com)
AdCC4
- Adenoid cystic cancer (AdCC) is a very rare type of cancer that can develop in many different body sites. (signssymptoms.org)
- Two cell lines (ACCS and ACCY) were isolated from two individuals with adenoid cystic carcinoma (AdCC) using tissue culture techniques. (aacrjournals.org)
- Adenoid cystic carcinoma , abbreviated AdCC , is a malignant tumour commonly seen in the salivary gland . (librepathology.org)
- BACKGROUND: Adenoid cystic carcinoma (AdCC) of the head and neck is an uncommon malignant epithelial tumour of the secretory glands. (uu.nl)
Diagnosis10
- To explore the epidemiology, diagnosis, treatment and future development of tracheal adenoid cystic carcinoma (TACC). (scirp.org)
- This paper reports the diagnosis and management of patients with asymptomatic primary tracheal adenoid cystic carcinoma invading the augmentation process, and also elaborates the current treatment of TACC and the direction of future development. (scirp.org)
- Adenoid cystic carcinoma is typically a morphologic diagnosis. (dermnetnz.org)
- Kimberly Smith admired her brother-in-law, Ryan Smith, not only for his kindness and thoughtfulness ― he always put others first ― but also for how he fought his diagnosis of stage IV adenoid cystic carcinoma (ACC), a rare cancer that arises within the secretory glands. (mdanderson.org)
- Diagnosis of adenoid cystic carcinoma generally occurs within 6 months of presenting signs and symptoms. (aao.org)
- The patient underwent surgical resection of the tumor and the submandibular gland with a histopathological exam that confirms the diagnosis of an adenoid cystic carcinoma of the submandibular gland. (radiopaedia.org)
- Conclusions: Bartholin's Gland Carcinoma is a rare condition with outcome dependent on duration of symptoms, including delay in diagnosis, cell-type, cellular differentiation and the International Federation of Gynecology and Obstetrics (FIGO) classification. (scirp.org)
- Histopathological diagnosis was adenoid cystic carcinoma of the trachea. (springer.com)
- Your doctor will give you the treatment depending on the stage of your adenoid cystic carcinoma, so the early diagnosis of this type of disease is very important, so you will get more chances of getting better. (homenaturalcures.com)
- It is important to talk with your doctor if you suspect that you may have risk factor for adenoid cystic carcinoma, because your doctor can give you the right diagnosis. (homenaturalcures.com)
Malignancy10
- Sinonasal adenoid cystic carcinoma (SNACC) is a rare malignancy that most commonly arises in the maxillary sinus. (wiley.com)
- BACKGROUND Adenoid cystic carcinoma (ACC) is a rare malignancy arising in salivary glands and other sites, characterized by high rates of relapse and distant spread. (jci.org)
- Adenoid cystic carcinoma (ACC), a relatively rare malignancy usually of salivary gland origin, has a signature v-myb avian myeloblastosis viral oncogene homolog-nuclear factor I/B (MYB-NFIB) gene fusion that activates MYB transcriptional regulatory activity. (nih.gov)
- Adenoid cystic carcinoma (ACC), the second most common salivary gland malignancy, is notorious for poor prognosis, which reflects the propensity of ACC to progress to clinically advanced metastatic disease. (nih.gov)
- Adenoid cystic carcinoma is the second most common malignancy of the salivary glands 1 . (appliedradiology.com)
- Adenoid cystic carcinoma (ACC) is a glandular epithelial malignancy, which frequently arises in secretary glands, especially the major and minor salivary glands. (aspetjournals.org)
- Adenoid cystic carcinoma (ACC) is a relatively uncommon salivary gland malignancy known for its protean phenotypic features and pernicious clinical behavior. (aacrjournals.org)
- Adenoid cystic carcinoma (ACC) is an uncommon salivary gland malignancy characterized by heterogeneous phenotypic features and persistently progressive biological behavior ( 1 - 6 ). (aacrjournals.org)
- PURPOSE Salivary gland adenoid cystic carcinoma (ACC) is a rare malignancy that is poorly understood. (semanticscholar.org)
- Adenoid cystic carcinoma (ACC) of the trachea and bronchus are rare primary bronchopulmonary carcinomas with low malignancy. (esmo.org)
Prognosis3
- Adenoid cystic carcinoma (ACC) is one of the most common malignant tumours of the salivary glands characterized by multiple recurrences and distant metastasis resulting in significantly worsening prognosis. (springer.com)
- Salivary adenoid cystic carcinoma (SACC) is a peculiar malignant tumor, characterized by its slow but inexorable growth, with a high incidence of lung metastasis and poor prognosis. (thno.org)
- Acinic cell carcinoma is usually slow growing with a fairly good prognosis. (cancer.ca)
SACC5
- Genistein induced cell cycle G2/M arrest in human salivary adenoid cystic carcinoma cell line SACC-83. (greenmedinfo.com)
- In this study, we aimed to explore the effect of BRD4 inhibition by JQ1 on in vitro cell growth, migration and invasion of salivary adenoid cystic carcinoma (SACC). (scielo.cl)
- Salivary Adenoid Cystic Carcinoma (SACC) is characterized by a high rate of local recurrence and infiltration, strong invasion to peripheral nerves or late distant metastasis. (plos.org)
- This study aims to analyze the expression of T-cell receptor γ chain alternate reading frame protein (TARP) in salivary adenoid cystic carcinoma (SACC) and its distant metastases and to investigate its influences on the development and progression of SACC. (ovid.com)
- Salivary adenoid cystic carcinoma (SACC) arises from the secretory epithelial cells of the salivary glands. (thno.org)
Cancer14
- Statistics adapted from the Adenoid Cystic Carcinoma Research Foundation, the National Organization for Rare Disorders, and the Oral Cancer Foundation (sources accessed January 2021). (cancer.net)
- Adenoid Cystic Carcinoma Organization International provides information about adenoid cystic carcinoma, a rare head and neck cancer, to people affected by the disease. (aacr.org)
- FISH studies performed on other histologic subtypes of lung cancer (10 squamous cell carcinomas, 10 adenocarcinomas, and 10 small-cell carcinomas) failed to show MYB rearrangement. (nih.gov)
- In one study by Ahmed and Esmaeli, a retrospective review of 53 cases of adenoid cystic carcinoma were classified according to the American Joint Committee on Cancer Classification to evaluate predictive outcomes of treatment and local recurrence. (aao.org)
- This 61-year-old woman presented with new primary triple negative breast cancer (TNBC) in the lateral breast 10 years after completing radiation for ductal carcinoma in situ (DCIS) in the same breast.1 Despite neoadjuvant chemotherapy and mastectomy with only residual DCIS and negative nodes, patient developed a TNBC re-recurrence only 9 months later. (medworm.com)
- MYB fusions and CD markers as tools for authentication and purification of cancer stem cells from salivary adenoid cystic carcinoma. (semanticscholar.org)
- Immune checkpoint blockade, and specifically inhibition of the programmed-death-1 (PD-1) pathway, has proven clinical benefit in the treatment of melanoma, non-small cell lung cancer, and renal cell carcinoma, and preliminary studies have demonstrated efficacy in an increasing number of other tumor types ( 1-11 ). (aacrjournals.org)
- Estrogen and progesterone receptor and p53 gene expression in adenoid cystic cancer. (ucdenver.edu)
- One of the most common tops of glandular cancer is Cystic Adenoid Carcinoma of the Lacrimal Gland ( some refers as Lacrimal Adenoid Carcinoma ) which affects the glands in your eyes that are responsible for creating tears. (carcinomacure.com)
- In parts of Asia, sinonasal malignancies (SNM) are the second most common head and neck cancer behind nasopharyngeal carcinoma. (medscape.com)
- Mucoepidermoid carcinoma (MEC) is the most common type of salivary gland cancer. (cancer.ca)
- Adenoid cystic carcinoma is the 2nd most common type of salivary gland cancer. (cancer.ca)
- Cribriform adenoid cystic carcinomas have cancer cells surrounded by normal cells. (cancer.ca)
- In many cases, the cancer has spread to lymph nodes when salivary duct carcinoma is diagnosed. (cancer.ca)
Neck12
- Adenoid cystic carcinoma (ACC) is an uncommon form of malignant neoplasm that arises within secretory glands, most commonly the major and minor salivary glands of the head and neck. (oralcancerfoundation.org)
- Adenoid cystic carcinoma of the head and neck. (oralcancerfoundation.org)
- Adenoid cystic carcinomas (ACCs) constitute of 1% of head and neck cancers. (clinicaltrials.gov)
- Prognostic factors affecting the clinical outcome of adenoid cystic carcinoma of the head and neck. (radiopaedia.org)
- Adenoid Cystic Carcinoma (ACC) is an uncommon malignant tumor, accounting for 3-5% of all neoplasms of the head and neck and approximately 22% of all salivary gland cancers [ 1 - 3 ]. (alliedacademies.org)
- Recurrent fusion of MYB and NFIB transcription factor genes in carcinomas of the breast and head and neck. (semanticscholar.org)
- Bradley PJ (2004) Adenoid cystic carcinoma of the head and neck: a review. (springer.com)
- Fordice J, Kershaw C, El-Naggar A, Goepfert H (1999) Adenoid cystic carcinoma of the head and neck: predictors of morbidity and mortality. (springer.com)
- Should we treat lung metastases from adenoid cystic carcinoma of the head and neck in asymptomatic patients? (entjournal.com)
- Adenoid cystic carcinoma of the head and neck: Incidence and survival trends based on 1973-2007 Surveillance, Epidemiology, and End Results data. (ucdenver.edu)
- The adenoid cystic carcinoma is uncommon form of malignant neoplasm which arises with secretory glands and it is most commonly happening in the major and minor salivary glands of the head and neck. (homenaturalcures.com)
- Management of adenoid cystic carcinoma of the head and neck: a single-institute study with over 25-year follow-up. (homenaturalcures.com)
Cribriform4
- Adenoid cystic carcinoma consists of infiltrative nests with prominent cribriform architecture (image C) & (image D) . (auanet.org)
- 2-10) Adenoid cystic carcinoma is a biphasic tumor composed of ductal and myoepithelial components with 3 major growth patterns: tubular, cribriform, and solid. (thefreelibrary.com)
- Primary cutaneous cribriform apocrine carcinoma: a clinicopathologic and immunohistochemical study of 26 cases of an under-recognized cutaneous adnexal neoplasm," Journal of the American Academy of Dermatology , vol. 61, no. 4, pp. 644-651, 2009. (hindawi.com)
- Cribriform is the most common form of adenoid cystic carcinoma. (cancer.ca)
Cases of adenoid cystic ca1
- The pathological types encountered were: 5 cases of malignant transformation of sinonasal inverted papilloma, 2 cases of maxillary sinus carcinoma, 3 cases of ethmoid sinus carcinoma, 11 cases of mucosal melanoma, 7 cases of olfactory neuroblastoma, 2 cases of neuroendocrine carcinoma, 4 cases of myoepithelial carcinoma, 3 cases of adenoid cystic carcinoma, 1 case of malignant hemangiopericytoma. (readbyqxmd.com)
Mucoepidermoid carcinoma3
- Pulmonary mucoepidermoid carcinoma (PMEC) and pulmonary adenoid cystic carcinoma (PACC) are the two major types of primary salivary gland-type (PSGT) lung cancers. (frontiersin.org)
- The two major subtypes of PSGT are pulmonary adenoid cystic carcinoma (PACC) and pulmonary mucoepidermoid carcinoma (PMEC). (frontiersin.org)
- Immunohistochemistry will help to show the biphasic appearance of the tumor, highlighting the basal or the luminal cells: Luminal cells: positive with CK7 and CD117 Basal cells: positive with p63, S100 protein and CK5/6 It is important to exclude a tumor which is directly extending into the ear canal from the parotid salivary gland, especially when dealing with an adenoid cystic or mucoepidermoid carcinoma. (wikipedia.org)
Major and minor sali1
- Adenoid cystic carcinoma of major and minor salivary gland origin. (openrepository.com)
Treat adenoid cystic ca2
- On its website, the organization maintains a list of international resources, information on treatment options, a directory of doctors who treat adenoid cystic carcinoma, and information about clinical trials. (aacr.org)
- Read about adenoid cystic carcinoma medical facts: what is the definition of adenoid cystic carcinoma, what are the signs and symptoms, medical treatment & how to treat adenoid cystic carcinoma, epidemiology, and related adenoid cystic carcinoma diseases. (signssymptoms.org)
Trachea2
- Djaković Ž, Janevski Z, Cesarec V, Slobodnjak Z, Stančić-Rokotov D. Adenoid Cystic Carcinoma of Distal Trachea: a Case Report. (srce.hr)
- We present a case of a 43-year-old patient with primary adenoid cystic carcinoma of distal trachea treated by emergency bronchoscopic recanalization and resection of the tracheal tumor with end-to-end anastomosis. (srce.hr)
Neoplasms2
- Adenoid cystic carcinoma-like pattern in spiradenoma and spiradenocylindroma: a rare feature in sporadic neoplasms and those associated with Brooke-Spiegler syndrome," The American Journal of Dermatopathology , vol. 31, no. 7, pp. 642-648, 2009. (hindawi.com)
- To summarize the characteristics of Adenoid Cystic Carcinoma (ACC) arising from nasopharynx by analysing 28 cases in a single center, in order to enhance the care of patients with these unusual neoplasms. (alliedacademies.org)
Epithelial5
- A carcinoma characterized by large epithelial masses containing round glandlike spaces or cysts, frequently containing mucus, that are bordered by layers of epithelial cells. (dictionary.com)
- Carcinoma characterized by bands or cylinders of hyalinized or mucinous stroma separating or surrounded by nests or cords of small epithelial cells. (curehunter.com)
- Epithelial-myoepithelial carcinoma of the maxillary sinus: a rare case. (readbyqxmd.com)
- Epithelial-myoepithelial carcinoma (EMC) is a rare tumor that commonly involves the salivary glands. (readbyqxmd.com)
- Epithelial-myoepithelial carcinoma - esp. (librepathology.org)
Clinicopathologic1
- Sinonasal Tract and Nasopharyngeal Adenoid Cystic Carcinoma: A Clinicopathologic and Immunophenotypic Study of 86 Cases. (librepathology.org)
Submandibular2
- And a phase I study has showed that one of three patients with submandibular adenoid cystic carcinoma achieved a partial response treated with Chidamide. (clinicaltrials.gov)
- A 65-year-old female presented to the breast care facility with a two-month history of a painful, palpable mass on the lateral aspect of her right breast, and a history of T3N0, stage III, adenoid cystic carcinoma (ACC) of the submandibular salivary gland with metastasis to the right lung. (appliedradiology.com)
Lacrimal gland1
- Fig. 1: Proptosis and globe dystopia from left lacrimal gland adenoid cystic carcinoma. (aao.org)
Immunohistochemistry1
- Micropapillary growth pattern calcifications have been noted reminiscent of salivary duct carcinoma, although the apocrine morphology is lacking and androgen receptor and HER2/neu are typically negative by immunohistochemistry. (thefreelibrary.com)
Basal Cell Carc4
- Basal cell carcinoma consists of variably sized solid nests, cords, or trabeculae with peripheral palisading of cells (image A) & (image B) . (auanet.org)
- A clinical, histological, and immunocytochemical comparison with adenoid cystic carcinoma of salivary glands and adenoid basal cell carcinoma," The American Journal of Dermatopathology , vol. 8, no. 1, pp. 2-13, 1986. (hindawi.com)
- Basal cell carcinoma (BCC). (librepathology.org)
- A clinical, histological, and immunocytochemical comparison with adenoid cystic carcinoma of salivary glands and adenoid basal cell carcinoma. (librepathology.org)
Tracheal5
- Tracheal adenoid cystic carcinoma that invades the tracheal prominence is a relatively rare tumor among thoracic diseases. (scirp.org)
- With asymptomatic invasion of the tracheal prominence, a case of tracheal adenoid cystic carcinoma with asymptomatic invasion of the tracheal prominence was reported. (scirp.org)
- Tracheal adenoid cystic carcinoma (TACC) is a salivary gland and derived from bronchial mucosa or submucosal glands. (scirp.org)
- At present, surgical treatment is the choice for tracheal adenoid cystic carcinoma. (scirp.org)
- Here, a patient with tracheal adenoid cystic carcinoma who had been previously diagnosed with difficult asthma was reported. (springer.com)
Misinterpreted as metastatic1
- Primary cutaneous adenoid cystic carcinomas have been misinterpreted as metastatic lesions. (wikipedia.org)
Inhibition2
- Although mTOR is clearly an attractive therapeutic target in tumor, no clinical study on mTOR inhibition by RAD001 has been systematically conducted in adenoid cystic carcinom. (bioportfolio.com)
- Radiosensitization of Adenoid Cystic Carcinoma with MDM2 Inhibition. (semanticscholar.org)
Parotid2
- His management would likely have relied on pain medications, and he would have missed his window of opportunity for timely intervention for parotid adenoid cystic carcinoma. (practicalpainmanagement.com)
- The purposes of this study are to report the first case of parotid gland adenoid cystic carcinoma metastatic to the choroid and discuss treatment approaches. (longdom.org)
Primary7
- At this time, the tumor was diagnosed as a primary adenoid cystic carcinoma of the ceruminous glands. (thefreelibrary.com)
- Low passage primary human adenoid cystic carcinoma cells (UM-HACC-2A,-2B,-5,-6) and patient-derived xenograft (PDX) models (UM-PDX-HACC) were developed from surgical specimens obtained from 4 patients. (sigmaaldrich.com)
- M. R. Wick and P. E. Swanson, "Primary adenoid cystic carcinoma of the skin. (hindawi.com)
- however, its identifica-tion is not trivial.3 Here, we illustrate an in situ adenoid cystic carcinoma partially involving a mammary duct in a 68-year-old woman with primary adenoid cystic carci-noma of the right breast. (iupui.edu)
- Lotan R, Ito H, Yasui W, Yokozaki H, Lotan D, Tahara E (1994) Expression of a 31-kDa lactoside-binding lectin in normal human gastric mucosa and in primary and metastatic gastric carcinomas. (springer.com)
- Primary Adenoid Cystic Carcinoma (ACC) occurring in the orbital apex is rare. (alliedacademies.org)
- Primary adenoid cystic carcinoma of the skin. (librepathology.org)
Tumour5
- This aged patient exemplifies a satisfying course of adenoid cystic carcinoma under VAE resulting in good quality of life and partial tumour regression. (greenmedinfo.com)
- Adenoid cystic carcinoma is a malignant tumour frequently described arising from seromucinous salivary tissue in the major and minor salivary glands. (gla.ac.uk)
- Salivary duct carcinoma is a very aggressive type of tumour that can advance quickly. (cancer.ca)
- It has a mix of different cell types, but the most common types of cells found in this tumour are sarcoma and carcinoma cells. (cancer.ca)
- For patients treated after only a biopsy, local tumour control was achieved in 37%, demonstrating the radioresponsiveness of this type of carcinoma. (openrepository.com)
Basaloid squamous carcinoma1
- In other sites, ACC may be confused on histologic grounds with a variant form of squamous carcinoma known as basaloid squamous carcinoma. (oralcancerfoundation.org)
Human salivary3
- Adenoid cystic carcinoma (ACC) is one of the most common malignancies to arise in human salivary glands, and it also arises in the glandular tissue of other organ systems. (semanticscholar.org)
- CpG island methylation profiling in human salivary gland adenoid cystic carcinoma. (semanticscholar.org)
- Promoter methylation as a common mechanism for inactivating E-cadherin in human salivary gland adenoid cystic carcinoma. (semanticscholar.org)
Clinical trials1
- Compare and research clinical trials and research studies related to Adenoid Cystic Carcinoma. (comparetrials.com)
Radiotherapy1
- Analysis of adenoid cystic carcinoma treated by radiotherapy. (openrepository.com)
Pleomorphic1
- During the past decade, a variant of ACC with areas of pleomorphic high-grade carcinoma has been recognized. (thefreelibrary.com)
Squamous cell carcinomas1
- A Bartholin's gland mass in a woman aged 40 years or more should be considered malignant until a biopsy proves otherwise.The incidence of Bartholin's Gland Carcinoma in Queensland is less than that reported elsewhere but a higher proportion of squamous cell carcinomas was found in this small series. (scirp.org)
Arising in salivary glands1
- Perzin KH, Gullane P, Clairmont AC (1978) Adenoid cystic carcinomas arising in salivary glands: a correlation of histologic features and clinical course. (springer.com)
Uncommon1
- This case illustrates an uncommon site, the Skene's glands, for adenoid cystic carcinoma in the female genitourinary tract. (elsevier.com)
Pulmonary adenoid2
- Effects of para-toluenesulfonamide intratumoral injection on pulmonary adenoid cystic carcinoma complicating with. (amegroups.com)
- Pulmonary adenoid cystic carcinoma (ACC) is a rare type of non-small cell lung carcinoma that may develop life-threatening severe malignant airway obstruction (SMAO). (amegroups.com)
Recurrence3
- BH3-mimetic small molecule inhibits the growth and recurrence of adenoid cystic carcinoma. (sigmaaldrich.com)
- Notably, single agent BM-1197 inhibited tumor recurrence, which is considered a major clinical challenge in the clinical management of adenoid cystic carcinoma. (sigmaaldrich.com)
- The recurrence of adenoid cystic carcinoma is most commonly diagnosed at the metastatic stage, which means it has spread to other parts of the body. (homenaturalcures.com)
Metastases3
- Of the malignancies that metastasize to the skin, carcinomas are the most common, but sarcomas, lymphomas and leukemias contribute to a large percent of skin metastases as well 3 . (appliedradiology.com)
- Overall, 78% of patients had adenoid cystic carcinoma of either the major or minor salivary glands, and 96.9% had distant metastases. (ascopost.com)
- Anatomic extent of lymph node metastases as an independent prognosticator in node-positive major salivary gland carcinoma: A study of the US SEER database and a Chinese multicenter cohort. (uchicago.edu)
Neoplasm2
- Adenoid cystic carcinoma (ACC) refers to a salivary gland neoplasm. (scirp.org)
- Tumor-induced angiogenesis is essential for invasive growth and hematogenous metastasis of adenoid cystic carcinoma (ACC), a highly aggressive neoplasm mostly occurring in salivary glands. (aspetjournals.org)