Lymphatic metastasis occurs when cancer cells enter the lymphatic vessels and are carried through the lymphatic system to other parts of the body. This can happen through several mechanisms, including:

1. Direct invasion: Cancer cells can invade the nearby lymphatic vessels and spread through them.
2. Lymphatic vessel embolization: Cancer cells can block the flow of lymphatic fluid and cause the formation of a clot-like structure, which can trap cancer cells and allow them to grow.
3. Lymphatic vessel invasion: Cancer cells can infiltrate the walls of lymphatic vessels and spread through them.

Lymphatic metastasis is a common mechanism for the spread of cancer, particularly in the breast, melanoma, and other cancers that have a high risk of lymphatic invasion. The presence of lymphatic metastasis in a patient's body can indicate a more aggressive cancer and a poorer prognosis.

Treatment for lymphatic metastasis typically involves a combination of surgery, chemotherapy, and radiation therapy. Surgery may be used to remove any affected lymph nodes or other tumors that have spread through the lymphatic system. Chemotherapy may be used to kill any remaining cancer cells, while radiation therapy may be used to shrink the tumors and relieve symptoms.

In summary, lymphatic metastasis is a common mechanism for the spread of cancer through the body, particularly in cancers that originate in organs with a high lymphatic drainage. Treatment typically involves a combination of surgery, chemotherapy, and radiation therapy to remove or shrink the tumors and relieve symptoms.

Benign ovarian neoplasms include:

1. Serous cystadenoma: A fluid-filled sac that develops on the surface of the ovary.
2. Mucinous cystadenoma: A tumor that is filled with mucin, a type of protein.
3. Endometrioid tumors: Tumors that are similar to endometrial tissue (the lining of the uterus).
4. Theca cell tumors: Tumors that develop in the supportive tissue of the ovary called theca cells.

Malignant ovarian neoplasms include:

1. Epithelial ovarian cancer (EOC): The most common type of ovarian cancer, which arises from the surface epithelium of the ovary.
2. Germ cell tumors: Tumors that develop from germ cells, which are the cells that give rise to eggs.
3. Stromal sarcomas: Tumors that develop in the supportive tissue of the ovary.

Ovarian neoplasms can cause symptoms such as pelvic pain, abnormal bleeding, and abdominal swelling. They can also be detected through pelvic examination, imaging tests such as ultrasound and CT scan, and biopsy. Treatment options for ovarian neoplasms depend on the type, stage, and location of the tumor, and may include surgery, chemotherapy, and radiation therapy.

Adrenocortical carcinoma can be subdivided into three main types based on their histological features:

1. Typical adrenocortical carcinoma: This is the most common type and accounts for about 70% of all cases. It is characterized by a large, irregular tumor that grows in the cortex of the adrenal gland.
2. Adenomatous adrenocortical carcinoma: This type is less aggressive than typical adrenocortical carcinoma and accounts for about 20% of cases. It is characterized by a small, well-circumscribed tumor that grows in the cortex of the adrenal gland.
3. Adrenocortical sarcoma: This is the least common type and accounts for about 10% of cases. It is characterized by a rare, malignant tumor that grows in the cortex of the adrenal gland.

Adrenocortical carcinoma can cause a variety of symptoms, including abdominal pain, weight loss, fatigue, and skin changes. The diagnosis is typically made through a combination of imaging studies, such as CT scans and MRI, and tissue biopsy. Treatment options include surgery, chemotherapy, and radiation therapy, and the prognosis depends on the stage and aggressiveness of the tumor.

Overall, adrenocortical carcinoma is a rare and aggressive cancer that requires prompt diagnosis and treatment to improve patient outcomes.

There are several types of colonic neoplasms, including:

1. Adenomas: These are benign growths that are usually precursors to colorectal cancer.
2. Carcinomas: These are malignant tumors that arise from the epithelial lining of the colon.
3. Sarcomas: These are rare malignant tumors that arise from the connective tissue of the colon.
4. Lymphomas: These are cancers of the immune system that can affect the colon.

Colonic neoplasms can cause a variety of symptoms, including bleeding, abdominal pain, and changes in bowel habits. They are often diagnosed through a combination of medical imaging tests (such as colonoscopy or CT scan) and biopsy. Treatment for colonic neoplasms depends on the type and stage of the tumor, and may include surgery, chemotherapy, and/or radiation therapy.

Overall, colonic neoplasms are a common condition that can have serious consequences if left untreated. It is important for individuals to be aware of their risk factors and to undergo regular screening for colon cancer to help detect and treat any abnormal growths or tumors in the colon.

Carcinoma verrucous is a type of squamous cell carcinoma that appears as a rough, bumpy, cauliflower-like lesion on the skin or mucous membranes. It is typically found in the oral cavity, lips, tongue, and penis. The tumor grows slowly, and the surface may be covered with a crust or scab that bleeds easily. Carcinoma verrucous tends to occur in older men, particularly those who smoke or drink excessively.

The exact cause of carcinoma verrucous is not known, but it is believed to be linked to exposure to certain viruses, such as human papillomavirus (HPV), and environmental factors, such as smoking and excessive alcohol consumption. The risk of developing carcinoma verrucous may also be increased by chronic inflammation, immunosuppression, and a diet low in fruits and vegetables.

The symptoms of carcinoma verrucous can vary depending on the location of the tumor. In the oral cavity, it may cause painless ulcers or bleeding gums, while in the penis, it may cause difficulty urinating or painful sexual activity. The diagnosis is made by a biopsy, which involves removing a small sample of tissue from the affected area and examining it under a microscope for cancer cells.

Carcinoma verrucous tends to grow slowly, and the prognosis is generally good if the tumor is completely removed before it spreads to other parts of the body. However, local recurrence is common, and the cancer can be difficult to treat once it has spread. The five-year survival rate for carcinoma verrucous is approximately 80%.

Carcinoma verrucous is often treated with surgery, and in some cases, radiation therapy or chemotherapy may also be recommended. Early detection and treatment are important to improve the chances of successful treatment and long-term survival.

A rare type of carcinoma that develops in the gastrointestinal tract (GI tract) such as stomach, small intestine, or large intestine is known as signet ring cell carcinoma. This cancerous tumor is characterized by its appearance under a microscope, which displays cells arranged in a signet ring pattern.

These cells have a distinctive round nucleus and prominent nucleoli that give them a characteristic signet ring appearance. Signet ring cell carcinomas tend to grow slowly, and they do not typically cause any symptoms until they reach an advanced stage.

Signet ring cell carcinoma can be difficult to diagnose because it often looks like other types of noncancerous conditions, such as inflammation or infection. To diagnose this condition, a healthcare provider will need to perform tests such as endoscopy, imaging studies (such as CT scan or MRI), and biopsy.

Treatment options for signet ring cell carcinoma include surgery to remove the tumor, chemotherapy, radiation therapy, or a combination of these. Treatment decisions depend on the stage of the cancer, location, and other factors such as patient's overall health status and personal preferences.

In summary, signet ring cell carcinoma is a rare type of gastrointestinal tract cancer characterized by its distinctive signet ring appearance under a microscope. It tends to grow slowly and can be difficult to diagnose until it reaches an advanced stage. Treatment options include surgery, chemotherapy, radiation therapy, or combination of these depending on the stage of the cancer and other factors.

Sources:
American Cancer Society. (2022). Signet Ring Cell Carcinoma of the Stomach. Retrieved from
National Cancer Institute. (2022). Signet Ring Cell Carcinoma of the Gastrointestinal Tract. Retrieved from

Neoplastic metastasis can occur in any type of cancer but are more common in solid tumors such as carcinomas (breast, lung, colon). It is important for cancer diagnosis and prognosis because metastasis indicates that the cancer has spread beyond its original site and may be more difficult to treat.

Metastases can appear at any distant location but commonly found sites include the liver, lungs, bones, brain, and lymph nodes. The presence of metastases indicates a higher stage of cancer which is associated with lower survival rates compared to localized cancer.

These tumors can be benign or malignant, and their growth and behavior vary depending on the type of cancer. Malignant tumors can invade the surrounding tissues and spread to other parts of the body through the bloodstream or lymphatic system, causing serious complications and potentially life-threatening consequences.

The risk factors for developing urinary bladder neoplasms include smoking, exposure to certain chemicals, recurrent bladder infections, and a family history of bladder cancer. The symptoms of these tumors can include blood in the urine, pain during urination, frequent urination, and abdominal pain.

Diagnosis of urinary bladder neoplasms is typically made through a combination of imaging tests such as ultrasound, computed tomography (CT) scan or magnetic resonance imaging (MRI), and cystoscopy, which involves inserting a flexible tube with a camera into the bladder to visualize the tumor.

Treatment options for urinary bladder neoplasms depend on the type of cancer, stage, and location of the tumor. Treatment may include surgery to remove the tumor, chemotherapy, radiation therapy, or a combination of these modalities. Early detection and treatment can improve the prognosis for patients with urinary bladder neoplasms.

There are several types of stomach neoplasms, including:

1. Adenocarcinoma: This is the most common type of stomach cancer, accounting for approximately 90% of all cases. It begins in the glandular cells that line the stomach and can spread to other parts of the body.
2. Squamous cell carcinoma: This type of cancer begins in the squamous cells that cover the outer layer of the stomach. It is less common than adenocarcinoma but more likely to be found in the upper part of the stomach.
3. Gastric mixed adenocarcinomasquamous cell carcinoma: This type of cancer is a combination of adenocarcinoma and squamous cell carcinoma.
4. Lymphoma: This is a cancer of the immune system that can occur in the stomach. It is less common than other types of stomach cancer but can be more aggressive.
5. Carcinomas of the stomach: These are malignant tumors that arise from the epithelial cells lining the stomach. They can be subdivided into adenocarcinoma, squamous cell carcinoma, and others.
6. Gastric brunner's gland adenoma: This is a rare type of benign tumor that arises from the Brunner's glands in the stomach.
7. Gastric polyps: These are growths that occur on the lining of the stomach and can be either benign or malignant.

The symptoms of stomach neoplasms vary depending on the location, size, and type of tumor. Common symptoms include abdominal pain, nausea, vomiting, weight loss, and difficulty swallowing. Diagnosis is usually made through a combination of endoscopy, imaging studies (such as CT or PET scans), and biopsy. Treatment depends on the type and stage of the tumor and may include surgery, chemotherapy, radiation therapy, or a combination of these. The prognosis for stomach neoplasms varies depending on the type and stage of the tumor, but early detection and treatment can improve outcomes.

There are several types of skin neoplasms, including:

1. Basal cell carcinoma (BCC): This is the most common type of skin cancer, and it usually appears as a small, fleshy bump or a flat, scaly patch. BCC is highly treatable, but if left untreated, it can grow and invade surrounding tissue.
2. Squamous cell carcinoma (SCC): This type of skin cancer is less common than BCC but more aggressive. It typically appears as a firm, flat, or raised bump on sun-exposed areas. SCC can spread to other parts of the body if left untreated.
3. Melanoma: This is the most serious type of skin cancer, accounting for only 1% of all skin neoplasms but responsible for the majority of skin cancer deaths. Melanoma can appear as a new or changing mole, and it's essential to recognize the ABCDE signs (Asymmetry, Border irregularity, Color variation, Diameter >6mm, Evolving size, shape, or color) to detect it early.
4. Sebaceous gland carcinoma: This rare type of skin cancer originates in the oil-producing glands of the skin and can appear as a firm, painless nodule on the forehead, nose, or other oily areas.
5. Merkel cell carcinoma: This is a rare and aggressive skin cancer that typically appears as a firm, shiny bump on the skin. It's more common in older adults and those with a history of sun exposure.
6. Cutaneous lymphoma: This type of cancer affects the immune system and can appear as a rash, nodules, or tumors on the skin.
7. Kaposi sarcoma: This is a rare type of skin cancer that affects people with weakened immune systems, such as those with HIV/AIDS. It typically appears as a flat, red or purple lesion on the skin.

While skin cancers are generally curable when detected early, it's important to be aware of your skin and notice any changes or unusual spots, especially if you have a history of sun exposure or other risk factors. If you suspect anything suspicious, see a dermatologist for an evaluation and potential biopsy. Remember, prevention is key to avoiding the harmful effects of UV radiation and reducing your risk of developing skin cancer.

This definition of 'Neoplasm Recurrence, Local' is from the Healthcare Professionals edition of the Merriam-Webster Medical Dictionary, copyright © 2007 by Merriam-Webster, Inc.

Also known as: Large cell carcinoma (LCC), malignant large cell carcinoma, and giant cell carcinoma.

The most common types of laryngeal neoplasms include:

1. Vocal cord nodules and polyps: These are benign growths that develop on the vocal cords due to overuse, misuse, or trauma.
2. Laryngeal papillomatosis: This is a condition where warts grow on the vocal cords, often caused by the human papillomavirus (HPV).
3. Adenoid cystic carcinoma: This is a rare type of cancer that develops in the salivary glands near the larynx.
4. Squamous cell carcinoma: This is the most common type of cancer that develops in the larynx, often due to smoking or heavy alcohol consumption.
5. Verrucous carcinoma: This is a rare type of cancer that develops on the vocal cords and is often associated with chronic inflammation.
6. Lymphoma: This is a type of cancer that affects the immune system, and can develop in the larynx.
7. Melanoma: This is a rare type of cancer that develops from pigment-producing cells called melanocytes.

Symptoms of laryngeal neoplasms can include hoarseness or difficulty speaking, breathing difficulties, and ear pain. Diagnosis is typically made through a combination of physical examination, imaging tests such as CT scans or MRI, and biopsy. Treatment options vary depending on the type and severity of the neoplasm, but may include surgery, radiation therapy, or chemotherapy.

Precancerous changes in the uterine cervix are called dysplasias, and they can be detected by a Pap smear, which is a routine screening test for women. If dysplasia is found, it can be treated with cryotherapy (freezing), laser therapy, or cone biopsy, which removes the affected cells.

Cervical cancer is rare in developed countries where Pap screening is widely available, but it remains a common cancer in developing countries where access to healthcare and screening is limited. The human papillomavirus (HPV) vaccine has been shown to be effective in preventing cervical precancerous changes and cancer.

Cervical cancer can be treated with surgery, radiation therapy, or chemotherapy, depending on the stage and location of the cancer. The prognosis for early-stage cervical cancer is good, but advanced-stage cancer can be difficult to treat and may have a poor prognosis.

The following are some types of uterine cervical neoplasms:

1. Adenocarcinoma in situ (AIS): This is a precancerous condition that occurs when glandular cells on the surface of the cervix become abnormal and grow out of control.
2. Cervical intraepithelial neoplasia (CIN): This is a precancerous condition that occurs when abnormal cells are found on the surface of the cervix. There are several types of CIN, ranging from mild to severe.
3. Squamous cell carcinoma: This is the most common type of cervical cancer and arises from the squamous cells that line the cervix.
4. Adnexal carcinoma: This is a rare type of cervical cancer that arises from the glands or ducts near the cervix.
5. Small cell carcinoma: This is a rare and aggressive type of cervical cancer that grows rapidly and can spread quickly to other parts of the body.
6. Micropapillary uterine carcinoma: This is a rare type of cervical cancer that grows in a finger-like shape and can be difficult to diagnose.
7. Clear cell carcinoma: This is a rare type of cervical cancer that arises from clear cells and can be more aggressive than other types of cervical cancer.
8. Adenocarcinoma: This is a type of cervical cancer that arises from glandular cells and can be less aggressive than squamous cell carcinoma.
9. Sarcoma: This is a rare type of cervical cancer that arises from the connective tissue of the cervix.

The treatment options for uterine cervical neoplasms depend on the stage and location of the cancer, as well as the patient's overall health and preferences. The following are some common treatments for uterine cervical neoplasms:

1. Hysterectomy: This is a surgical procedure to remove the uterus and may be recommended for early-stage cancers or precancerous changes.
2. Cryotherapy: This is a minimally invasive procedure that uses liquid nitrogen to freeze and destroy abnormal cells in the cervix.
3. Laser therapy: This is a minimally invasive procedure that uses a laser to remove or destroy abnormal cells in the cervix.
4. Cone biopsy: This is a surgical procedure to remove a small cone-shaped sample of tissue from the cervix to diagnose and treat early-stage cancers or precancerous changes.
5. Radiation therapy: This is a non-surgical treatment that uses high-energy rays to kill cancer cells and may be recommended for more advanced cancers or when the cancer has spread to other parts of the body.
6. Chemotherapy: This is a non-surgical treatment that uses drugs to kill cancer cells and may be recommended for more advanced cancers or when the cancer has spread to other parts of the body.
7. Immunotherapy: This is a non-surgical treatment that uses drugs to stimulate the immune system to fight cancer cells and may be recommended for more advanced cancers or when other treatments have failed.
8. Targeted therapy: This is a non-surgical treatment that uses drugs to target specific genes or proteins that contribute to cancer growth and development and may be recommended for more advanced cancers or when other treatments have failed.

It is important to note that the choice of treatment will depend on the stage and location of the cancer, as well as the patient's overall health and preferences. Patients should discuss their treatment options with their doctor and develop a personalized plan that is right for them.

Multiple primary neoplasms can arise in different organs or tissues throughout the body, such as the breast, colon, prostate, lung, or skin. Each tumor is considered a separate entity, with its own unique characteristics, including size, location, and aggressiveness. Treatment for multiple primary neoplasms typically involves surgery, chemotherapy, radiation therapy, or a combination of these modalities.

The diagnosis of multiple primary neoplasms can be challenging due to the overlapping symptoms and radiological findings between the different tumors. Therefore, it is essential to have a thorough clinical evaluation and diagnostic workup to rule out other possible causes of the symptoms and confirm the presence of multiple primary neoplasms.

Multiple primary neoplasms are more common than previously thought, with an estimated prevalence of 2% to 5% in some populations. The prognosis for patients with multiple primary neoplasms varies depending on the location, size, and aggressiveness of each tumor, as well as the patient's overall health status.

It is important to note that multiple primary neoplasms are not the same as metastatic cancer, in which a single primary tumor spreads to other parts of the body. Multiple primary neoplasms are distinct tumors that arise independently from different primary sites within the body.

Adenocarcinoma, follicular accounts for approximately 15% of all thyroid cancers and is more common in women than men. This type of cancer tends to be less aggressive than other types of thyroid cancer, such as papillary carcinoma, but it can still recur (come back) after treatment and spread to other parts of the body (metastasize).

Treatment options for adenocarcinoma, follicular include surgery to remove the tumor, radioactive iodine therapy, and hormone therapy. The prognosis is generally good for patients with this type of cancer, especially if it is detected early and treated appropriately.

In summary, adenocarcinoma, follicular is a type of thyroid cancer that originates in the glands (follicles) of the thyroid gland. It tends to be less aggressive than other types of thyroid cancer but can still recur and spread to other parts of the body. Treatment options include surgery, radioactive iodine therapy, and hormone therapy.

Examples of 'Adenocarcinoma, Mucinous' in medical literature:

* The patient was diagnosed with adenocarcinoma, mucinous type, in their colon after undergoing a colonoscopy and biopsy. (From the Journal of Clinical Oncology)

* The patient had a history of adenocarcinoma, mucinous type, in their breast and was being monitored for potential recurrence. (From the Journal of Surgical Oncology)

* The tumor was found to be an adenocarcinoma, mucinous type, with a high grade and was treated with surgery and chemotherapy. (From the Journal of Gastrointestinal Oncology)

Synonyms for 'Adenocarcinoma, Mucinous' include:

* Mucinous adenocarcinoma
* Colon adenocarcinoma, mucinous type
* Rectal adenocarcinoma, mucinous type
* Adenocarcinoma of the colon and rectum, mucinous type.

Examples of precancerous conditions include:

1. Dysplasia: This is a condition where abnormal cells are present in the tissue, but have not yet invaded surrounding tissues. Dysplasia can be found in organs such as the cervix, colon, and breast.
2. Carcinoma in situ (CIS): This is a condition where cancer cells are present in the tissue, but have not yet invaded surrounding tissues. CIS is often found in organs such as the breast, prostate, and cervix.
3. Atypical hyperplasia: This is a condition where abnormal cells are present in the tissue, but they are not yet cancerous. Atypical hyperplasia can be found in organs such as the breast and uterus.
4. Lobular carcinoma in situ (LCIS): This is a condition where cancer cells are present in the milk-producing glands of the breasts, but have not yet invaded surrounding tissues. LCIS is often found in both breasts and can increase the risk of developing breast cancer.
5. Adenomas: These are small growths on the surface of the colon that can become malignant over time if left untreated.
6. Leukoplakia: This is a condition where thick, white patches develop on the tongue or inside the mouth. Leukoplakia can be a precancerous condition and may increase the risk of developing oral cancer.
7. Oral subsquamous carcinoma: This is a type of precancerous lesion that develops in the mouth and can progress to squamous cell carcinoma if left untreated.
8. Cervical intraepithelial neoplasia (CIN): This is a condition where abnormal cells are present on the surface of the cervix, but have not yet invaded surrounding tissues. CIN can progress to cancer over time if left untreated.
9. Vulvar intraepithelial neoplasia (VIN): This is a condition where abnormal cells are present on the vulva, but have not yet invaded surrounding tissues. VIN can progress to cancer over time if left untreated.
10. Penile intraepithelial neoplasia (PIN): This is a condition where abnormal cells are present on the penis, but have not yet invaded surrounding tissues. PIN can progress to cancer over time if left untreated.

It is important to note that not all precancerous conditions will develop into cancer, and some may resolve on their own without treatment. However, it is important to follow up with a healthcare provider to monitor any changes and determine the best course of treatment.

The term "papillary" refers to the fact that the cancer cells grow in a finger-like shape, resembling a papilla. The term "follicular" refers to the fact that the cancer cells grow near or within glands (follicles). Both types of cancer are considered relatively low-grade, meaning they tend to grow slowly and do not aggressively invade surrounding tissue.

It's important to note that while these types of carcinomas are generally less aggressive than other types of breast or thyroid cancer, they can still be serious and require prompt medical attention. If you suspect you may have symptoms of papillary or follicular carcinoma, it is essential to consult with a healthcare professional for proper diagnosis and treatment.

Types of Gallbladder Neoplasms:

1. Adenoma: A benign tumor that grows in the gallbladder wall and can become malignant over time if left untreated.
2. Cholangiocarcinoma: A rare and aggressive malignant tumor that arises in the gallbladder or bile ducts.
3. Gallbladder cancer: A general term used to describe any type of cancer that develops in the gallbladder, including adenocarcinoma, squamous cell carcinoma, and other rare types.

Causes and Risk Factors:

1. Genetics: A family history of gallbladder disease or certain genetic conditions can increase the risk of developing gallbladder neoplasms.
2. Chronic inflammation: Long-standing inflammation in the gallbladder, such as that caused by gallstones or chronic bile duct obstruction, can increase the risk of developing cancer.
3. Obesity: Being overweight or obese may increase the risk of developing gallbladder neoplasms.
4. Age: The risk of developing gallbladder neoplasms increases with age, with most cases occurring in people over the age of 50.

Symptoms and Diagnosis:

1. Abdominal pain: Pain in the upper right abdomen is a common symptom of gallbladder neoplasms.
2. Jaundice: Yellowing of the skin and eyes can occur if the cancer blocks the bile ducts.
3. Weight loss: Unexplained weight loss can be a symptom of some types of gallbladder neoplasms.
4. Fatigue: Feeling tired or weak can be a symptom of some types of gallbladder neoplasms.

Diagnosis is typically made through a combination of imaging tests such as CT scans, MRI scans, and PET scans, and a biopsy to confirm the presence of cancer cells.

Treatment:

1. Surgery: Surgery is the primary treatment for gallbladder neoplasms. The type of surgery depends on the stage and location of the cancer.
2. Chemotherapy: Chemotherapy may be used in combination with surgery to treat advanced or aggressive cancers.
3. Radiation therapy: Radiation therapy may be used in combination with surgery to treat advanced or aggressive cancers.
4. Watchful waiting: For early-stage cancers, a wait-and-watch approach may be taken, where the patient is monitored regularly with imaging tests to see if the cancer progresses.

Prognosis:
The prognosis for gallbladder neoplasms depends on the stage and location of the cancer at the time of diagnosis. In general, the earlier the cancer is detected and treated, the better the prognosis. For early-stage cancers, the 5-year survival rate is high, while for advanced cancers, the prognosis is poor.

Complications:

1. Bile duct injury: During surgery, there is a risk of damaging the bile ducts, which can lead to complications such as bile leakage or bleeding.
2. Infection: There is a risk of infection after surgery, which can be serious and may require hospitalization.
3. Pancreatitis: Gallbladder cancer can cause inflammation of the pancreas, leading to pancreatitis.
4. Jaundice: Cancer of the gallbladder can block the bile ducts, leading to jaundice and other complications.
5. Spread of cancer: Gallbladder cancer can spread to other parts of the body, such as the liver or lymph nodes, which can reduce the chances of a cure.

Adenocarcinoma is the most common subtype of NSCLC and is characterized by malignant cells that have glandular or secretory properties. Squamous cell carcinoma is less common and is characterized by malignant cells that resemble squamous epithelium. Large cell carcinoma is a rare subtype and is characterized by large, poorly differentiated cells.

The main risk factor for developing NSCLC is tobacco smoking, which is responsible for approximately 80-90% of all cases. Other risk factors include exposure to secondhand smoke, radon gas, asbestos, and certain chemicals in the workplace or environment.

Symptoms of NSCLC can include coughing, chest pain, shortness of breath, and fatigue. The diagnosis is typically made through a combination of imaging studies such as CT scans, PET scans, and biopsy. Treatment options for NSCLC can include surgery, chemotherapy, radiation therapy, or a combination of these. The prognosis for NSCLC depends on several factors, including the stage of the cancer, the patient's overall health, and the effectiveness of treatment.

Overall, NSCLC is a common and aggressive form of lung cancer that can be treated with a variety of therapies. Early detection and treatment are critical for improving outcomes in patients with this diagnosis.

Endometrial neoplasms are abnormal growths or tumors that develop in the lining of the uterus, known as the endometrium. These growths can be benign (non-cancerous) or malignant (cancerous). The most common type of endometrial neoplasm is endometrial hyperplasia, which is a condition where the endometrium grows too thick and can become cancerous if left untreated. Other types of endometrial neoplasms include endometrial adenocarcinoma, which is the most common type of uterine cancer, and endometrial sarcoma, which is a rare type of uterine cancer that develops in the muscle or connective tissue of the uterus.

Endometrial neoplasms can be caused by a variety of factors, including hormonal imbalances, genetic mutations, and exposure to certain chemicals or radiation. Risk factors for developing endometrial neoplasms include obesity, early onset of menstruation, late onset of menopause, never being pregnant or having few or no full-term pregnancies, and taking hormone replacement therapy or other medications that can increase estrogen levels.

Symptoms of endometrial neoplasms can include abnormal vaginal bleeding, painful urination, and pelvic pain or discomfort. Treatment for endometrial neoplasms depends on the type and stage of the condition, and may involve surgery, radiation therapy, chemotherapy, or hormone therapy. In some cases, a hysterectomy (removal of the uterus) may be necessary.

In summary, endometrial neoplasms are abnormal growths that can develop in the lining of the uterus and can be either benign or malignant. They can be caused by a variety of factors and can cause symptoms such as abnormal bleeding and pelvic pain. Treatment depends on the type and stage of the condition, and may involve surgery, radiation therapy, chemotherapy, or hormone therapy.

Clear cell adenocarcinomas can occur in various parts of the body, such as the ovary, pancreas, and lung. In general, clear cell adenocarcinomas tend to grow more slowly than other types of cancer and are less aggressive. However, they can still be malignant and may require treatment.

The prognosis for clear cell adenocarcinoma depends on various factors, such as the stage of the cancer (how far it has spread) and the specific location of the tumor. In general, the prognosis for clear cell adenocarcinoma is good if the cancer is caught early and treated appropriately. However, if the cancer has spread to other parts of the body, the prognosis may be poorer.

There are several treatment options for clear cell adenocarcinoma, including surgery, chemotherapy, radiation therapy, and targeted therapy. The specific treatment plan will depend on the stage and location of the cancer, as well as other individual factors such as age and overall health.

In summary, clear cell adenocarcinoma is a type of cancer that begins in glandular cells and has clear cells. It can occur in various parts of the body and tends to grow slowly, but it can still be malignant and require treatment. The prognosis for clear cell adenocarcinoma depends on various factors, and there are several treatment options available.

Disease progression can be classified into several types based on the pattern of worsening:

1. Chronic progressive disease: In this type, the disease worsens steadily over time, with a gradual increase in symptoms and decline in function. Examples include rheumatoid arthritis, osteoarthritis, and Parkinson's disease.
2. Acute progressive disease: This type of disease worsens rapidly over a short period, often followed by periods of stability. Examples include sepsis, acute myocardial infarction (heart attack), and stroke.
3. Cyclical disease: In this type, the disease follows a cycle of worsening and improvement, with periodic exacerbations and remissions. Examples include multiple sclerosis, lupus, and rheumatoid arthritis.
4. Recurrent disease: This type is characterized by episodes of worsening followed by periods of recovery. Examples include migraine headaches, asthma, and appendicitis.
5. Catastrophic disease: In this type, the disease progresses rapidly and unpredictably, with a poor prognosis. Examples include cancer, AIDS, and organ failure.

Disease progression can be influenced by various factors, including:

1. Genetics: Some diseases are inherited and may have a predetermined course of progression.
2. Lifestyle: Factors such as smoking, lack of exercise, and poor diet can contribute to disease progression.
3. Environmental factors: Exposure to toxins, allergens, and other environmental stressors can influence disease progression.
4. Medical treatment: The effectiveness of medical treatment can impact disease progression, either by slowing or halting the disease process or by causing unintended side effects.
5. Co-morbidities: The presence of multiple diseases or conditions can interact and affect each other's progression.

Understanding the type and factors influencing disease progression is essential for developing effective treatment plans and improving patient outcomes.

The causes of colorectal neoplasms are not fully understood, but factors such as age, genetics, diet, and lifestyle have been implicated. Symptoms of colorectal cancer can include changes in bowel habits, blood in the stool, abdominal pain, and weight loss. Screening for colorectal cancer is recommended for adults over the age of 50, as it can help detect early-stage tumors and improve survival rates.

There are several subtypes of colorectal neoplasms, including adenomas (which are precancerous polyps), carcinomas (which are malignant tumors), and lymphomas (which are cancers of the immune system). Treatment options for colorectal cancer depend on the stage and location of the tumor, but may include surgery, chemotherapy, radiation therapy, or a combination of these.

Research into the causes and treatment of colorectal neoplasms is ongoing, and there has been significant progress in recent years. Advances in screening and treatment have improved survival rates for patients with colorectal cancer, and there is hope that continued research will lead to even more effective treatments in the future.

1. Squamous cell carcinoma: This is the most common type of tongue cancer, accounting for about 90% of all cases. It usually starts on the front two-thirds of the tongue and can spread to other parts of the mouth and throat.
2. Verrucous carcinoma: This type of cancer is less aggressive than squamous cell carcinoma but can still invade surrounding tissues. It typically occurs on the lateral or back part of the tongue.
3. Papillary carcinoma: This type of cancer is rare and usually affects young people. It starts in the mucous glands on the surface of the tongue and tends to grow slowly.
4. Lymphoma: This type of cancer affects the immune system and can occur in various parts of the body, including the tongue. There are different subtypes of lymphoma that can affect the tongue, such as Hodgkin's lymphoma and non-Hodgkin's lymphoma.
5. Mucoepidermoid carcinoma: This is a rare type of cancer that usually affects children and young adults. It tends to grow slowly and can occur anywhere on the tongue, but it is most common on the front part of the tongue.

The symptoms of tongue neoplasms can vary depending on the type and location of the tumor. Common symptoms include:

* A lump or mass on the tongue that may be painful or tender to the touch
* Bleeding or discharge from the tongue
* Difficulty speaking, swallowing, or moving the tongue
* Pain in the tongue or mouth that does not go away
* A sore throat or ear pain

If you suspect you may have a tongue neoplasm, it is important to see a doctor for an evaluation. A biopsy can be performed to determine the type of tumor and develop a treatment plan. Treatment options can vary depending on the type and location of the tumor, but may include surgery, radiation therapy, chemotherapy, or a combination of these.

Pancreatic adenocarcinoma is the most common type of malignant pancreatic neoplasm and accounts for approximately 85% of all pancreatic cancers. It originates in the glandular tissue of the pancreas and has a poor prognosis, with a five-year survival rate of less than 10%.

Pancreatic neuroendocrine tumors (PNETs) are less common but more treatable than pancreatic adenocarcinoma. These tumors originate in the hormone-producing cells of the pancreas and can produce excess hormones that cause a variety of symptoms, such as diabetes or high blood sugar. PNETs are classified into two main types: functional and non-functional. Functional PNETs produce excess hormones and are more aggressive than non-functional tumors.

Other rare types of pancreatic neoplasms include acinar cell carcinoma, ampullary cancer, and oncocytic pancreatic neuroendocrine tumors. These tumors are less common than pancreatic adenocarcinoma and PNETs but can be equally aggressive and difficult to treat.

The symptoms of pancreatic neoplasms vary depending on the type and location of the tumor, but they often include abdominal pain, weight loss, jaundice, and fatigue. Diagnosis is typically made through a combination of imaging tests such as CT scans, endoscopic ultrasound, and biopsy. Treatment options for pancreatic neoplasms depend on the type and stage of the tumor but may include surgery, chemotherapy, radiation therapy, or a combination of these.

Prognosis for patients with pancreatic neoplasms is generally poor, especially for those with advanced stages of disease. However, early detection and treatment can improve survival rates. Research into the causes and mechanisms of pancreatic neoplasms is ongoing, with a focus on developing new and more effective treatments for these devastating diseases.

The term "serous" refers to the fact that the tumor produces a fluid-filled cyst, which typically contains a clear, serous (watery) liquid. The cancer cells are typically found in the outer layer of the ovary, near the surface of the organ.

Cystadenocarcinoma, serous is the most common type of ovarian cancer, accounting for about 50-60% of all cases. It is often diagnosed at an advanced stage, as it can be difficult to detect in its early stages. Symptoms may include abdominal pain, bloating, and changes in bowel or bladder habits.

Treatment for cystadenocarcinoma, serous usually involves a combination of surgery and chemotherapy. Surgery may involve removing the uterus, ovaries, and other affected tissues, followed by chemotherapy to kill any remaining cancer cells. In some cases, radiation therapy may also be used.

Prognosis for cystadenocarcinoma, serous varies depending on the stage of the cancer at diagnosis. Women with early-stage disease have a good prognosis, while those with advanced-stage disease have a poorer outlook. However, overall survival rates have improved in recent years due to advances in treatment and screening.

In summary, cystadenocarcinoma, serous is a type of ovarian cancer that originates in the lining of the ovary and grows slowly over time. It can be difficult to detect in its early stages, but treatment typically involves surgery and chemotherapy. Prognosis varies depending on the stage of the cancer at diagnosis.

The tumor cells are typically small, uniform, and well-differentiated, with a distinct cell border and a central nucleus. The tumor cells are often arranged in a glandular or tubular pattern, which is characteristic of this type of cancer.

Carcinoma, Lewis lung usually affects older adults, with the median age at diagnosis being around 60 years. Men are slightly more likely to be affected than women. The main risk factor for developing this type of cancer is smoking, although it can also occur in people who have never smoked.

The symptoms of Carcinoma, Lewis lung can vary depending on the location and size of the tumor, but they may include:

* Chest pain or discomfort
* Coughing up blood
* Shortness of breath
* Fatigue
* Weight loss

If you suspect you may have Carcinoma, Lewis lung or are experiencing any of these symptoms, it is important to consult a healthcare professional for an accurate diagnosis and appropriate treatment.

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Types of Bronchial Neoplasms:

1. Adenocarcinoma: This is the most common type of lung cancer and accounts for approximately 40% of all lung cancers. It originates in the glandular cells that line the bronchi.
2. Squamous Cell Carcinoma: This type of lung cancer originates in the squamous cells that line the bronchi. It is the second most common type of lung cancer, accounting for approximately 25% of all lung cancers.
3. Small Cell Lung Cancer (SCLC): This type of lung cancer is highly aggressive and accounts for approximately 10% of all lung cancers. It originates in the small cells that line the bronchi.
4. Large Cell Carcinoma: This type of lung cancer is rare and accounts for approximately 5% of all lung cancers. It originates in the large cells that line the bronchi.
5. Bronchioloalveolar Carcinoma (BAC): This type of lung cancer originates in the small air sacs (alveoli) and is rare, accounting for approximately 2% of all lung cancers.
6. Lymphoma: This type of cancer originates in the immune system cells that line the bronchi. It is rare, accounting for approximately 1% of all lung cancers.
7. Carcinoid Tumors: These are rare types of lung cancer that originate in the neuroendocrine cells that line the bronchi. They are typically slow-growing and less aggressive than other types of lung cancer.
8. Secondary Cancers: These are cancers that have spread to the lungs from other parts of the body, such as breast cancer or colon cancer.

Diagnosis of Bronchial Neoplasms:

1. Medical History and Physical Examination: A thorough medical history and physical examination are essential for diagnosing bronchial neoplasms. The doctor will ask questions about the patient's symptoms, risk factors, and medical history.
2. Chest X-Ray: A chest X-ray is often the first diagnostic test performed to evaluate the lungs for any abnormalities.
3. Computed Tomography (CT) Scan: A CT scan is a more detailed imaging test that uses X-rays and computer technology to produce cross-sectional images of the lungs. It can help identify the size, location, and extent of the tumor.
4. Positron Emission Tomography (PET) Scan: A PET scan is a diagnostic test that uses small amounts of radioactive material to visualize the metabolic activity of the cells in the lungs. It can help identify the presence of cancerous cells and determine the effectiveness of treatment.
5. Biopsy: A biopsy involves taking a sample of tissue from the lung and examining it under a microscope for cancerous cells. It is a definitive diagnostic test for bronchial neoplasms.
6. Bronchoscopy: Bronchoscopy is a procedure in which a thin, flexible tube with a camera on the end is inserted through the nose or mouth and guided to the lungs. It can help identify any abnormalities in the airways and obtain a biopsy sample.
7. Magnetic Resonance Imaging (MRI): An MRI uses magnetic fields and radio waves to produce detailed images of the lungs and surrounding tissues. It is not as commonly used for diagnosing bronchial neoplasms as other imaging tests, but it may be recommended in certain cases.
8. Ultrasound: An ultrasound uses high-frequency sound waves to produce images of the lungs and surrounding tissues. It is not typically used as a diagnostic test for bronchial neoplasms, but it may be used to evaluate the spread of cancer to other parts of the body.

It's important to note that the specific diagnostic tests and procedures used will depend on the individual case and the suspicion of malignancy. Your doctor will discuss the best course of action with you based on your symptoms, medical history, and test results.

1. Parotid gland tumors: These are the most common type of salivary gland tumor and can be benign or malignant.
2. Submandibular gland tumors: These are less common than parotid gland tumors but can also be benign or malignant.
3. Sublingual gland tumors: These are rare and usually benign.
4. Warthin's tumor: This is a type of benign tumor that affects the parotid gland.
5. Mucoepidermoid carcinoma: This is a type of malignant tumor that can occur in any of the major salivary glands.
6. Acinic cell carcinoma: This is a rare type of malignant tumor that usually occurs in the parotid gland.
7. Adenoid cystic carcinoma: This is a slow-growing malignant tumor that can occur in any of the major salivary glands.
8. Metastatic tumors: These are tumors that have spread to the salivary glands from another part of the body.

Salivary gland neoplasms can cause a variety of symptoms, including painless lumps or swelling in the neck or face, difficulty swallowing, and numbness or weakness in the face. Treatment options depend on the type and stage of the tumor and may include surgery, radiation therapy, and/or chemotherapy.

In conclusion, salivary gland neoplasms are a diverse group of cancers that affect the salivary glands, and it's important to be aware of the different types, symptoms, and treatment options in order to provide effective care for patients with these tumors.

Explanation: Neoplastic cell transformation is a complex process that involves multiple steps and can occur as a result of genetic mutations, environmental factors, or a combination of both. The process typically begins with a series of subtle changes in the DNA of individual cells, which can lead to the loss of normal cellular functions and the acquisition of abnormal growth and reproduction patterns.

Over time, these transformed cells can accumulate further mutations that allow them to survive and proliferate despite adverse conditions. As the transformed cells continue to divide and grow, they can eventually form a tumor, which is a mass of abnormal cells that can invade and damage surrounding tissues.

In some cases, cancer cells can also break away from the primary tumor and travel through the bloodstream or lymphatic system to other parts of the body, where they can establish new tumors. This process, known as metastasis, is a major cause of death in many types of cancer.

It's worth noting that not all transformed cells will become cancerous. Some forms of cellular transformation, such as those that occur during embryonic development or tissue regeneration, are normal and necessary for the proper functioning of the body. However, when these transformations occur in adult tissues, they can be a sign of cancer.

See also: Cancer, Tumor

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The term "papillary" refers to the fact that the cancer cells grow in a finger-like shape, with each cell forming a small papilla (bump) on the surface of the tumor. APC is often slow-growing and may not cause any symptoms in its early stages.

APC is generally considered to be less aggressive than other types of cancer, such as ductal carcinoma in situ (DCIS) or invasive breast cancer. However, it can still spread to other parts of the body if left untreated. Treatment options for APC may include surgery, radiation therapy, and/or hormone therapy, depending on the location and stage of the cancer.

It's worth noting that APC is sometimes referred to as "papillary adenocarcinoma" or simply "papillary cancer." However, these terms are often used interchangeably with "adenocarcinoma, papillary" in medical literature and clinical practice.

Examples of 'Mammary Neoplasms, Experimental' in a sentence:

1. The researchers studied the effects of hormone therapy on mammary neoplasms in experimental animals to better understand its potential role in human breast cancer.
2. The lab used mice with genetic mutations that predispose them to developing mammary neoplasms to test the efficacy of new cancer drugs.
3. In order to investigate the link between obesity and breast cancer, the researchers conducted experiments on mammary neoplasms in rats with diet-induced obesity.

Pathologic neovascularization can be seen in a variety of conditions, including cancer, diabetic retinopathy, and age-related macular degeneration. In cancer, for example, the formation of new blood vessels can help the tumor grow and spread to other parts of the body. In diabetic retinopathy, the growth of new blood vessels in the retina can cause vision loss and other complications.

There are several different types of pathologic neovascularization, including:

* Angiosarcoma: a type of cancer that arises from the cells lining blood vessels
* Hemangiomas: benign tumors that are composed of blood vessels
* Cavernous malformations: abnormal collections of blood vessels in the brain or other parts of the body
* Pyogenic granulomas: inflammatory lesions that can form in response to trauma or infection.

The diagnosis of pathologic neovascularization is typically made through a combination of physical examination, imaging studies (such as ultrasound, CT scans, or MRI), and biopsy. Treatment options vary depending on the underlying cause of the condition, but may include medications, surgery, or radiation therapy.

In summary, pathologic neovascularization is a process that occurs in response to injury or disease, and it can lead to serious complications. It is important for healthcare professionals to be aware of this condition and its various forms in order to provide appropriate diagnosis and treatment.

CBASQ is characterized by the presence of both squamous and basal cell features, with a mixed pattern of keratinization and a high proliferation rate. The tumor cells are positive for cytokeratins (such as cytokeratin 5/6) and negative for melanoma-specific markers (such as HMB-45 and S100).

The diagnosis of CBASQ requires a thorough clinical evaluation, including a history of prolonged sun exposure, and a biopsy to confirm the presence of both squamous and basal cell features. Treatment typically involves surgical excision with a wide margin, and may also involve adjuvant therapies such as radiation therapy or chemotherapy for more advanced cases.

The prognosis for CBASQ is generally poorer than for other types of skin cancer, due to its aggressive nature and tendency to recur. However, early detection and treatment can improve outcomes and reduce the risk of metastasis.

Types of experimental neoplasms include:

* Xenografts: tumors that are transplanted into animals from another species, often humans.
* Transgenic tumors: tumors that are created by introducing cancer-causing genes into an animal's genome.
* Chemically-induced tumors: tumors that are caused by exposure to certain chemicals or drugs.

The use of experimental neoplasms in research has led to significant advances in our understanding of cancer biology and the development of new treatments for the disease. However, the use of animals in cancer research is a controversial topic and alternatives to animal models are being developed and implemented.

Rectal neoplasms refer to abnormal growths or tumors that occur in the rectum, which is the lower part of the digestive system. These growths can be benign (non-cancerous) or malignant (cancerous).

Types of Rectal Neoplasms:

There are several types of rectal neoplasms, including:

1. Adenoma: A benign growth that is usually found in the colon and rectum. It is a common precursor to colorectal cancer.
2. Carcinoma: A malignant tumor that arises from the epithelial cells lining the rectum. It is the most common type of rectal cancer.
3. Rectal adenocarcinoma: A type of carcinoma that originates in the glandular cells lining the rectum.
4. Rectal squamous cell carcinoma: A type of carcinoma that originates in the squamous cells lining the rectum.
5. Rectal melanoma: A rare type of carcinoma that originates in the pigment-producing cells (melanocytes) of the rectum.

Causes and Risk Factors:

The exact causes of rectal neoplasms are not known, but several factors can increase the risk of developing these growths. These include:

1. Age: The risk of developing rectal neoplasms increases with age, with most cases occurring in people over the age of 50.
2. Family history: Having a family history of colorectal cancer or polyps can increase the risk of developing rectal neoplasms.
3. Inflammatory bowel disease: People with inflammatory bowel disease, such as ulcerative colitis and Crohn's disease, are at higher risk of developing rectal neoplasms.
4. Diet: A diet high in fat and low in fiber may increase the risk of developing rectal neoplasms.
5. Lifestyle factors: Factors such as smoking, obesity, and lack of physical activity may also increase the risk of developing rectal neoplasms.

Symptoms:

The symptoms of rectal neoplasms can vary depending on the type and location of the growth. Some common symptoms include:

1. Blood in the stool
2. Changes in bowel movements (such as diarrhea or constipation)
3. Abdominal pain or discomfort
4. Weakness and fatigue
5. Loss of appetite

Diagnosis:

To diagnose rectal neoplasms, a doctor may perform several tests, including:

1. Digital rectal exam (DRE): A doctor will insert a gloved finger into the rectum to feel for any abnormalities.
2. Colonoscopy: A flexible tube with a camera and light on the end is inserted through the anus and into the rectum to examine the inside of the rectum and colon for polyps or other abnormalities.
3. Imaging tests: Such as X-rays, CT scans, or MRI scans to visualize the growth and determine its location and size.
4. Biopsy: A sample of tissue is removed from the rectum and examined under a microscope for cancer cells.

Treatment:

The treatment of rectal neoplasms depends on the type, location, and stage of the growth. Some common treatments include:

1. Polypectomy: Removal of polyps through a colonoscopy or surgery.
2. Local excision: Surgical removal of the tumor and a small amount of surrounding tissue.
3. Radiation therapy: High-energy beams are used to kill cancer cells.
4. Chemotherapy: Drugs are used to kill cancer cells.
5. Immunotherapy: A treatment that uses the body's immune system to fight cancer.

Prognosis:

The prognosis for rectal neoplasms depends on the type, location, and stage of the growth. In general, the earlier the diagnosis and treatment, the better the prognosis. However, some types of rectal neoplasms can be more aggressive and difficult to treat, and may have a poorer prognosis.

Prevention:

There is no sure way to prevent rectal neoplasms, but there are several screening tests that can help detect them early, including:

1. Colonoscopy: A test in which a flexible tube with a camera and light on the end is inserted into the rectum and colon to examine for polyps or cancer.
2. Fecal occult blood test (FOBT): A test that checks for blood in the stool.
3. Flexible sigmoidoscopy: A test similar to a colonoscopy, but only examines the lower part of the colon and rectum.
4. Digital rectal exam (DRE): An examination of the rectum using a gloved finger to feel for any abnormalities.

It is important to talk to your doctor about your risk for rectal neoplasms and any screening tests that may be appropriate for you. Early detection and treatment can improve the prognosis for these types of growths.