Carcinoid heart disease. Medical search

Cardiac manifestation of gastrointestinal CARCINOID TUMOR that metastasizes to the liver. Substances secreted by the tumor cells, including SEROTONIN, promote fibrous plaque formation in ENDOCARDIUM and its underlying layers. These deposits cause distortion of the TRICUSPID VALVE and the PULMONARY VALVE eventually leading to STENOSIS and valve regurgitation.

A symptom complex associated with CARCINOID TUMOR and characterized by attacks of severe flushing of the skin, diarrheal watery stools, bronchoconstriction, sudden drops in blood pressure, edema, and ascites. The carcinoid tumors are usually located in the gastrointestinal tract and metastasize to the liver. Symptoms are caused by tumor secretion of serotonin, prostaglandins, and other biologically active substances. Cardiac manifestations constitute CARCINOID HEART DISEASE. (Dorland, 27th ed; Stedman, 25th ed)

A usually small, slow-growing neoplasm composed of islands of rounded, oxyphilic, or spindle-shaped cells of medium size, with moderately small vesicular nuclei, and covered by intact mucosa with a yellow cut surface. The tumor can occur anywhere in the gastrointestinal tract (and in the lungs and other sites); approximately 90% arise in the appendix. It is now established that these tumors are of neuroendocrine origin and derive from a primitive stem cell. (From Stedman, 25th ed & Holland et al., Cancer Medicine, 3d ed, p1182)

The pathologic narrowing of the orifice of the TRICUSPID VALVE. This hinders the emptying of RIGHT ATRIUM leading to elevated right atrial pressure and systemic venous congestion. Tricuspid valve stenosis is almost always due to RHEUMATIC FEVER.

Flaps of tissue that prevent regurgitation of BLOOD from the HEART VENTRICLES to the HEART ATRIA or from the PULMONARY ARTERIES or AORTA to the ventricles.

Backflow of blood from the RIGHT VENTRICLE into the RIGHT ATRIUM due to imperfect closure of the TRICUSPID VALVE.

Pathological conditions involving any of the various HEART VALVES and the associated structures (PAPILLARY MUSCLES and CHORDAE TENDINEAE).

The valve consisting of three cusps situated between the right atrium and right ventricle of the heart.

A valve situated at the entrance to the pulmonary trunk from the right ventricle.

Prosthesis, usually heart valve, composed of biological material and whose durability depends upon the stability of the material after pretreatment, rather than regeneration by host cell ingrowth. Durability is achieved 1, mechanically by the interposition of a cloth, usually polytetrafluoroethylene, between the host and the graft, and 2, chemically by stabilization of the tissue by intermolecular linking, usually with glutaraldehyde, after removal of antigenic components, or the use of reconstituted and restructured biopolymers.

Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.

The hollow, muscular organ that maintains the circulation of the blood.

Carcinoid heart disease from ovarian primary presenting with acute pericarditis and biventricular failure. (1/47)

A case is described of a 54 year old woman who had acute pericarditis with large exudative effusion accompanied by severe right and left ventricular failure. The patient was finally diagnosed with carcinoid heart disease from an ovarian carcinoid teratoma. She was treated with octreotide--a somatostatin analogue--followed by radical surgical resection of the neoplasm. At one year follow up only mild carcinoid tricuspid regurgitation remained. Only 16 cases of carcinoid heart disease from an ovarian primary have been described in literature. Moreover clinically manifest acute, nonmetastatic pericarditis and left heart failure are not considered as possible presentations of carcinoid heart disease, whatever the origin. In a recent series a small pericardial effusion was considered an infrequent and unexpected echocardiographic finding in carcinoid heart patients. One case of "carcinoid pericarditis" has previously been described as a consequence of pericardial metastasis. Left sided heart involvement is usually caused by bronchial carcinoids or patency of foramen ovale; both were excluded in the case presented. (+info)

Balloon pulmonary valvuloplasty in carcinoid syndrome. (2/47)

Half of all patients with carcinoid syndrome develop cardiac involvement. Patients who have cardiac involvement have a significantly worse prognosis than those without, and death can occur directly as a result of cardiac involvement. A case of carcinoid syndrome in a 38 year old woman with lesions in the liver, who presented with right sided valvar abnormalities, a dilated right ventricle, and right ventricular pressure overload, is presented. In order to palliate the patient's symptoms and to decrease right sided pressures before major abdominal surgery, balloon pulmonary valvuloplasty was performed at the time of cardiac catheterisation. This resulted in a reduction in the pulmonary gradient and right ventricular pressure. Following the procedure, the patient's symptoms were completely relieved. She went on to laparotomy where the lesions in the liver were excised without complication. (+info)

Tricuspid and pulmonary valve involvement in carcinoid disease. (3/47)

We report the case of a 62-year-old woman in whom carcinoid disease had been diagnosed 6 years earlier. She subsequently developed tricuspid and pulmonary valve disease. Both valves were incompetent and mildly stenotic. The tricuspid valve required surgery; the pulmonary vaive was explored but not treated. Valve surgery in patients with carcinoid disease is discussed in light of the prognosis of these patients, the timing of valvular lesion presentation, and the choice of prosthesis. The justification for multiple-valve procedures in such cases is also considered. (+info)

Perianaesthetic risks and outcomes of abdominal surgery for metastatic carcinoid tumours. (4/47)

Patients with metastatic carcinoid tumours often undergo surgical procedures to reduce the tumour burden and associated debilitating symptoms. These procedures and anaesthesia can precipitate a life-threatening carcinoid crisis. To assess perioperative outcomes, we studied retrospectively the medical records of adult patients from 1983 to 1996 who underwent abdominal surgery for metastatic carcinoid tumours. Preoperative risk factors, intraoperative complications and complications occurring in the 30 days after surgery were recorded. Perioperative complications or death occurred in 15 of 119 patients (12.6%, exact confidence interval 7.2-19.9). None of the 45 patients who received octreotide intraoperatively experienced intraoperative complications compared with eight of the 73 patients (11.0%) who did not receive octreotide (P=0.023). The presence of carcinoid heart disease and high urinary output of 5-hydroxyindoleacetic acid preoperatively were statistically significant risk factors for perioperative complications. (+info)

Surgical management of left-sided carcinoid heart disease. (5/47)

BACKGROUND: Carcinoid involvement of left-sided heart valves has been reported in patients with a patent foramen ovale, carcinoid tumor of the lung, and active carcinoid syndrome with high levels of serotonin. The present study details the clinical features and surgical management of patients with carcinoid heart disease affecting both left- and right-sided valves. METHODS AND RESULTS: Eleven patients (7 men, 4 women) with symptomatic carcinoid heart disease underwent surgery for left- and right-sided valve disease between 1989 and 1999. Mean age was 57+/-9 years, and median preoperative NYHA class was 3. All patients had metastatic carcinoid tumors and were on somatostatin analog. Of 11 patients, 5 (45%) had a patent foramen ovale; 1 of these also had a primary lung carcinoid tumor. Surgery included tricuspid valve replacement in all patients, pulmonary valve replacement in 3 and valvectomy in 7, mitral valve replacement in 6 and repair in 1, aortic valve replacement in 4 and repair in 2, CABG in 2, and patent foramen ovale closure in 5. One myocardial metastatic carcinoid tumor was removed. There were 2 perioperative deaths. At a mean follow-up of 41 months, 4 additional patients were dead. All but 1 surgical survivor initially improved >/=1 functional class. No patient required reoperation. CONCLUSIONS: Carcinoid heart disease may affect left- and right-sided valves and occurred without intracardiac shunting in 55% of this surgical series. Despite metastatic disease that limits longevity, operative survivors had improvement in functional capacity. Cardiac surgery should be considered for select patients with carcinoid heart disease affecting left- and right-sided valves. (+info)

Carcinoid heart disease: successful tricuspid valve replacement. (6/47)

A woman aged 46 was found to have severe tricuspid valve disease 14 years after the diagnosis of a malignant carcinoid tumour of the ileum and 33 years after the onset of symptoms attributable to the disease. Increasing ascites requiring repeated paracentesis had not responded to chemotherapy including infusion of 5-fluorouracil and vincristine into the coeliac artery. The tricuspid valve was replaced by a Bjork-Shiley prosthesis. After operation there was no recurrence of ascites or oedema. She remains well one year and 11 months later. It is suggested that valve replacement surgery should be considered more often in patients with carcinoid heart disease. Hepatomegaly and ascites sould not be attributed too readily to advancing malignant disease without careful consideration of the role of right-sided valvar lesions in the production of these signs. (+info)

Cardiovascular abnormalities in patients with a carcinoid syndrome. (7/47)

BACKGROUND: Heart failure is an important reason for morbidity and mortality in patients with carcinoid. Carcinoid heart disease is caused by increased levels of circulating serotonin. Because carcinoids also produce catecholamines, we evaluated cardiovascular manifestations of autonomic dysfunction in patients with a carcinoid syndrome. METHODS: Twenty patients with a midgut carcinoid, who had a carcinoid syndrome with a median duration of 72 months, and markedly elevated urinary 5-hydroxyindoleacetic acid (5-HIAA) excretion were studied. RESULTS: Ten patients had no symptoms of heart failure, i.e. New York Heart Association (NYHA) functional class I, 6 had class II, and 4 class III heart failure. Transthoracic echocardiography (TTE) showed right-sided valvular abnormalities in 13 of 19 evaluable patients (mild n=8, severe n=5). Fourteen of the 20 patients (70%) had an elevated concentration of plasma N-terminal atrial natriuretic peptide (N-ANP), which correlated with NYHA class, TTE abnormalities, and increased urinary metanephrine excretion. Heart rate variability (HRV) parameters, in particular those associated with increased sympathetic activity (low frequency power, p=0.002 versus healthy individuals), were impaired but were independent of NYHA class and TTE findings and correlated with urinary metanephrine excretion (r=-0.49, p<0.05). CONCLUSION: In these 20 carcinoid patients with substantial secretory activity of the tumour, overt cardiac morphological changes were present in a minority of patients. However, N-ANP values and HRV profile were markedly abnormal, and related to enhanced urinary excretion of catecholamine and metabolites, suggesting autonomic derangement. These abnormalities possibly herald the development of more severe cardiac dysfunction and may be indicative of the need for preventive drug treatment. (+info)

Echocardiographic diagnosis in carcinoid heart disease. (8/47)

In this case report the typical echocardiographic features of carcinoid heart disease are presented. Newer treatments such as the use of a somatostatin analogue, interferon and hepatic de-arterialisation have improved the prognosis in patients with carcinoid syndrome. Nevertheless this syndrome portends a poor prognosis in patients with cardiac involvement. Cardiac lesions are mainly located in the right side of the heart. Regurgitation and stenosis of the tricuspid and pulmonary valve, leading to right heart failure, are the most common cardiac manifestations of the disease. Elevated levels of serotonin are probably responsible for the development of these cardiac lesions. Despite treatment resulting in significant reductions of urinary levels of 5-HIAA, regression of the cardiac manifestations in carcinoid syndrome has not been observed. Two-dimensional and Doppler echocardiography are the main tools to establish the diagnosis and severity of carcinoid heart disease. Cardiac surgery for carcinoid heart disease might improve symptoms and longevity, but the scarce data report on early mortality of over 35%. (+info)

Carcinoid heart disease is caused by the release of hormones and other chemicals from the carcinoid tumor into the bloodstream. These substances can cause damage to the heart muscle and blood vessels, leading to a range of symptoms including:

* Shortness of breath
* Fatigue
* Swelling in the legs, ankles, and feet (edema)
* Pain in the chest or abdomen
* Rapid or irregular heartbeat (arrhythmia)
* Coughing up blood (hemoptysis)

Carcinoid heart disease can lead to serious complications such as heart failure, atrial fibrillation, and pulmonary embolism. Diagnosis of carcinoid heart disease typically involves a combination of physical examination, medical history, imaging tests (such as CT or MRI scans), and laboratory tests (such as measurements of hormone levels in the blood).

Treatment for carcinoid heart disease depends on the underlying cause of the condition and may include:

* Medications to control symptoms such as shortness of breath, fatigue, and rapid heartbeat
* Chemotherapy or other treatments to shrink the carcinoid tumor
* Surgery to remove the tumor or repair damaged blood vessels
* Radiation therapy to destroy cancer cells.

Prognosis for patients with carcinoid heart disease depends on several factors, including the size and location of the tumor, the extent of damage to the heart and blood vessels, and the patient's overall health. In general, early detection and treatment of carcinoid heart disease can improve outcomes and reduce the risk of complications.

The main symptoms of MCS include:

1. Diarrhea: One of the most common symptoms of MCS is diarrhea, which can be severe and watery.
2. Flushing: A characteristic flushing of the face, neck, and rest of the body, often accompanied by a feeling of warmth.
3. Abdominal pain: Pain in the abdomen is common, particularly if the tumor has spread to other organs.
4. Weight loss: MCS can lead to weight loss due to decreased appetite and malabsorption.
5. Fatigue: Patients with MCS often experience fatigue, which can be severe.
6. Nausea and vomiting: These symptoms are common in patients with MCS.
7. Shortness of breath: If the tumor has spread to the lungs, shortness of breath may occur.
8. Coughing up blood: This is a rare but serious complication of MCS.

The diagnosis of MCS is based on a combination of clinical symptoms, laboratory tests, and imaging studies. Treatment options for MCS include chemotherapy, targeted therapy, and somatostatin analogs, which are medications that can help reduce the symptoms of the syndrome.

In conclusion, malignant carcinoid syndrome is a rare but serious condition that can cause a range of symptoms, including diarrhea, flushing, abdominal pain, weight loss, fatigue, nausea and vomiting, shortness of breath, and coughing up blood. Early diagnosis and treatment are crucial to improve the prognosis for patients with MCS.

Carcinoid tumors are usually found in the appendix, small intestine, rectum, or other parts of the gastrointestinal tract. They can also occur in the lungs, pancreas, or other organs. These tumors tend to grow slowly and often do not cause any symptoms until they have grown quite large.

Carcinoid tumors are diagnosed through a combination of imaging tests such as CT scans, MRI scans, and endoscopies, along with a biopsy to confirm the presence of cancer cells. Treatment for carcinoid tumors depends on the location, size, and stage of the tumor, as well as the patient's overall health. Treatment options may include surgery, chemotherapy, radiation therapy, or a combination of these.

Some of the symptoms that may be associated with carcinoid tumors include:

* Flushing (redness and warmth of the skin)
* Wheezing
* Shortness of breath
* Abdominal pain
* Diarrhea
* Weight loss

Carcinoid tumors are relatively rare, accounting for only about 1% to 5% of all cancer cases. However, they tend to be more common in certain parts of the world, such as North America and Europe. The exact cause of carcinoid tumors is not known, but they are thought to be linked to genetic mutations that occur during fetal development.

Overall, while carcinoid tumors are rare and can be challenging to diagnose and treat, advances in medical technology and cancer research have improved the outlook for patients with these types of tumors. With early detection and appropriate treatment, many people with carcinoid tumors can achieve long-term survival and a good quality of life.

The symptoms of TVS may include:

1. Shortness of breath
2. Fatigue
3. Swelling in the legs, ankles, and feet
4. Chest pain
5. Dizziness or lightheadedness
6. Pale or blue-tinged skin
7. Fast or irregular heartbeat

If TVS is suspected, a doctor may perform a physical examination, take a medical history, and order diagnostic tests such as:

1. Chest X-ray
2. ECG (electrocardiogram)
3. Echocardiogram (echo)
4. Cardiac MRI
5. Cardiac catheterization

Treatment options for TVS may include:

1. Medications to manage symptoms and slow disease progression, such as diuretics, beta blockers, and ACE inhibitors.
2. Balloon valvuloplasty or valve replacement surgery, which can help to widen the tricuspid valve and improve blood flow.
3. Heart transplantation, which may be considered for patients with severe TVS who are not candidates for other treatments.

It is important to note that TVS is a relatively rare condition compared to other cardiac conditions, but it can be associated with other congenital heart defects or acquired heart diseases. A thorough evaluation by a cardiologist or cardiac surgeon is necessary for proper diagnosis and treatment.

There are several causes of tricuspid valve insufficiency, including:

1. Congenital heart defects: Tricuspid valve insufficiency can be present at birth due to abnormal development of the tricuspid valve.
2. Rheumatic fever: This is an inflammatory condition that can damage the tricuspid valve and lead to insufficiency.
3. Endocarditis: Bacterial infection of the inner lining of the heart, including the tricuspid valve, can cause damage and lead to insufficiency.
4. Heart failure: As the heart fails, the tricuspid valve may become less effective, leading to insufficiency.
5. Cardiac tumors: Tumors in the heart can put pressure on the tricuspid valve and cause insufficiency.
6. Congenital heart disease: Tricuspid valve insufficiency can be present at birth due to abnormal development of the tricuspid valve.
7. Chronic pulmonary disease: This can lead to increased pressure in the right side of the heart, causing tricuspid valve insufficiency.

Symptoms of tricuspid valve insufficiency may include fatigue, shortness of breath, swelling in the legs and feet, and chest pain. Diagnosis is typically made through echocardiography, electrocardiography, and cardiac catheterization.

Treatment options for tricuspid valve insufficiency depend on the severity of the condition and may include:

1. Medications: Diuretics, ACE inhibitors, and beta blockers may be used to manage symptoms and slow progression of the disease.
2. Surgery: In severe cases, surgical repair or replacement of the tricuspid valve may be necessary.
3. Transcatheter tricuspid valve replacement: This is a minimally invasive procedure in which a new tricuspid valve is inserted through a catheter in the femoral vein and placed in the heart.
4. Watchful waiting: In mild cases, doctors may choose to monitor the condition closely without immediate treatment.

There are several types of heart valve diseases, including:

1. Mitral regurgitation: This occurs when the mitral valve does not close properly, allowing blood to flow backward into the left atrium.
2. Aortic stenosis: This occurs when the aortic valve becomes narrowed or blocked, restricting blood flow from the left ventricle into the aorta.
3. Pulmonary stenosis: This occurs when the pulmonary valve becomes narrowed or blocked, restricting blood flow from the right ventricle into the pulmonary artery.
4. Tricuspid regurgitation: This occurs when the tricuspid valve does not close properly, allowing blood to flow backward into the right atrium.
5. Heart valve thickening or calcification: This can occur due to aging, rheumatic fever, or other conditions that cause inflammation in the heart.
6. Endocarditis: This is an infection of the inner lining of the heart, which can damage the heart valves.
7. Rheumatic heart disease: This is a condition caused by rheumatic fever, which can damage the heart valves and cause scarring.
8. Congenital heart defects: These are heart defects that are present at birth, and can affect the heart valves as well as other structures of the heart.

Symptoms of heart valve disease can include shortness of breath, fatigue, swelling in the legs or feet, and chest pain. Treatment options for heart valve disease depend on the specific condition and can range from medication to surgery or other procedures.

Fox DJ, Khattar RS (2004). "Carcinoid heart disease: presentation, diagnosis, and management". Heart. 90 (10): 1224-8. doi: ... Carcinoid tumors are also found in the lungs. Metastasis of carcinoid can lead to carcinoid syndrome. This is due to the over- ... Carcinoid tumors of the midgut (jejunum, ileum, appendix, and cecum) are associated with carcinoid syndrome. Carcinoid tumors ... and right-sided cardiac valve disease. It is estimated that less than 6% of carcinoid patients will develop carcinoid syndrome ...

https://en.wikipedia.org/wiki/Carcinoid

2004 Jun;32(3):170-5. Carcinoid heart disease. Clinical and echocardiographic spectrum in 74 patients. Pellikka PA, Tajik AJ, ... Chapter 10: Heart. "Rheumatic heart disease". Heart & Stroke. Heart and Stroke Foundation of Canada. 2022. "Rheumatic heart ... Pulmonary and tricuspid valve diseases are right heart diseases. Pulmonary valve diseases are the least common heart valve ... Valvular heart disease is any cardiovascular disease process involving one or more of the four valves of the heart (the aortic ...

https://en.wikipedia.org/wiki/Valvular_heart_disease

Carcinoid heart disease: About 19% to 60% of the those affected by carcinoid syndrome develop carcinoid heart disease. ... Disease progression is difficult to ascertain because the disease can metastasize anywhere in the body and can be too small to ... Serotonin induces fibrosis in valves of the right heart especially tricuspid valve. Carcinoid tumors produce several vasoactive ... Carcinoid syndrome is a paraneoplastic syndrome comprising the signs and symptoms that occur secondary to carcinoid tumors. The ...

https://en.wikipedia.org/wiki/Carcinoid_syndrome

"Improving outcome of valve replacement for carcinoid heart disease". The Journal of Thoracic and Cardiovascular Surgery. 158 (1 ... "Valvular heart disease and the use of dopamine agonists for Parkinson's disease". The New England Journal of Medicine. 356 (1 ... Certain diseases such as neuroendocrine tumor of the small intestine (also known by the obsolete term carcinoid), which ... December 2007). "Heart valve regurgitation, pergolide use, and parkinson disease: an observational study and meta-analysis". ...

https://en.wikipedia.org/wiki/Cardiac_fibrosis

August 2007). "Percutaneous closure of a patent foramen ovale in left-sided carcinoid heart disease". Nat Clin Pract Cardiovasc ... Congenital Heart Disease in Comprehensive Pediatric Hospital Medicine. Zaoutis LB, Chiang VW. 2007. ISBN 0-323-03004-1 Partial ... Barry A. Love M.D. is a cardiologist specializing in pediatric and congenital heart problems. Love is currently director of the ... Katie Charles (January 20, 2011). "Congenital heart problems can be spotted even before birth". New York Daily News. Retrieved ...

https://en.wikipedia.org/wiki/Barry_A._Love

"Percutaneous closure of a patent foramen ovale in left-sided carcinoid heart disease". Nat Clin Pract Cardiovasc Med. 4 (8): ... Clinical investigation topics include congestive heart failure, Raynaud's disease and mitral valve disease. Extramural honors ... Heart Rhythm Society, International Society for Adult Congenital Heart Disease, Society for Cardiovascular Angiography and ... December 2008). "ACC/AHA 2008 guidelines for the management of adults with congenital heart disease: a report of the American ...

https://en.wikipedia.org/wiki/Jonathan_L._Halperin

Carcinoid heart disease was identified in 1952, and carcinoid fibrosis in 1961. Neuroendocrine tumors were sometimes called ... The Carcinoid Cancer Foundation: Carcinoid Symposium 2002) carcinoid.org Archived 2015-01-05 at the Wayback Machine Benson AB, ... In malignant carcinoid tumors with carcinoid syndrome, the median survival has improved from two years to more than eight years ... There may be associated atypical carcinoid syndrome, acromegaly, Cushing disease, other endocrine disorders, telangiectasia, or ...

https://en.wikipedia.org/wiki/Neuroendocrine_tumor

About Pulmonary valve disease , Patient". Patient. Retrieved 2015-11-18. Choices, NHS. "Congenital heart disease - Types - NHS ... it may also be due to a malignant carcinoid tumor. Both stenosis of the pulmonary artery and pulmonary valve stenosis are forms ... Valvular Heart Disease. Springer Science & Business Media. p. 266. ISBN 9781597454117. "Pulmonary Valve Disease. ... "Congenital heart disease - Treatment - NHS Choices". www.nhs.uk. Retrieved 2015-11-18. "Balloon dilatation of pulmonary valve ...

https://en.wikipedia.org/wiki/Pulmonary_valve_stenosis

"Congenital heart defects and fetal alcohol spectrum disorders". Congenital Heart Disease. 2 (4): 250-255. doi:10.1111/j.1747- ... and leftsided carcinoid heartdisease (mitral valve). No cause is established for a foramen ovale to remain open instead of ... "Patent Foramen Ovale". Texas Heart Institute Heart Information Center. "Patent Foramen Ovale (PFO)". www.heart.org. Furlan AJ, ... ASDs make up 30 to 40% of all congenital heart diseases that are seen in adults. The ostium secundum atrial septal defect ...

https://en.wikipedia.org/wiki/Atrial_septal_defect

... malignant carcinoid syndrome MeSH C04.557.465.625.650.200.500.205 - carcinoid heart disease MeSH C04.557.465.625.650.240 - ... malignant carcinoid syndrome MeSH C04.557.470.200.025.200.500.205 - carcinoid heart disease MeSH C04.557.470.200.025.215 - ... malignant carcinoid syndrome MeSH C04.557.580.625.650.200.500.205 - carcinoid heart disease MeSH C04.557.580.625.650.240 - ... hodgkin disease MeSH C04.557.386.390 - immunoproliferative small intestinal disease MeSH C04.557.386.480 - lymphoma, non- ...

https://en.wikipedia.org/wiki/List_of_MeSH_codes_(C04)

Pulmonary hypertension Infective endocarditis Rheumatic heart disease Connective tissue disease Carcinoid syndrome Congenital ... Chaturvedi, Rajiv R; Redington, Andrew N (2007-07-01). "Pulmonary regurgitation in congenital heart disease". Heart. 93 (7): ... "Pulmonary Valve Disease. About Pulmonary valve disease , Patient". Patient. Retrieved 2015-08-29. McGlothlin, edited by Michael ... Valvular heart disease, Vascular diseases, Medical signs). ... "pulmonary Valve disease". Patient.info. EMIS Group. Retrieved ...

https://en.wikipedia.org/wiki/Pulmonary_insufficiency

... thromboembolism Myocardial disease Right ventricular ischemia and infraction Left to right shunt Carcinoid heart disease In ... is a type of valvular heart disease in which the tricuspid valve of the heart, located between the right atrium and right ... Chronic rheumatic heart diseases, Valvular heart disease). ... Moss and Adams heart disease in infants, children, and ... However, the murmur may be inaudible due to the relatively low pressures in the right side of the heart. A third heart sound ...

https://en.wikipedia.org/wiki/Tricuspid_regurgitation

... myopathies Pseudoxanthoma elasticum Sarcomeric protein disorders Werner's syndrome Endomyocardial Carcinoid heart disease ... "Worsening of congestive heart failure in amyloid heart disease treated by calcium channel-blocking agents". American Journal of ... Primary hyperoxaluria Storage diseases Fabry disease Gaucher disease Hereditary hemochromatosis Glycogen storage disease ... "restrictive cardiomyopathy" at Dorland's Medical Dictionary Pathophysiology of heart disease : a collaborative project of ...

https://en.wikipedia.org/wiki/Restrictive_cardiomyopathy

... liver disease. Selim Sesler, 57, Turkish clarinet player. Mary Stewart, 97, British novelist (Merlin series), heart failure. ... Don Meyer, 69, American basketball coach (Hamline Pipers, Lipscomb Bisons, Northern State Wolves), carcinoid cancer. Chukwuedu ... heart disease. John Vasconcellos, 82, American politician, member of the California State Assembly (1966-1996) and Senate (1996 ... Henning Carlsen, 86, Danish Bodil Award-winning film director (Hunger, People Meet and Sweet Music Fills the Heart). Robert ...

https://en.wikipedia.org/wiki/Deaths_in_May_2014

"Siegfried oberndorfer and the evolution of carcinoid disease". Archives of Surgery. 142 (2): 187-197. doi:10.1001/archsurg. ... diarrhea and in some cases fibrosis of the heart valves.[citation needed] There are often several small and highly fibrotic ... The disease was named by Siegfried Oberndorfer, a German pathologist, in 1907. A large fraction of cases are diagnosed after ... A small intestine neuroendocrine tumor is a carcinoid in the distal small intestine or the proximal large intestine. It is a ...

https://en.wikipedia.org/wiki/Small_intestine_neuroendocrine_tumor

Males are more likely to develop a horseshoe kidney with a preponderance of 2:1. Certain genetic diseases can predispose ... Kidney cancer - increased frequency of certain renal cancers such as transitional cell tumors, Wilms tumors, and carcinoid ... Heart abnormalities - ventricular septal defect Neurological abnormalities - encephalocoele, myelomeningocoele, spina bifida ... adult polycystic kidney disease, and more than two kidneys. Genetic abnormalities - Turner syndrome, Down syndrome, Patau ...

https://en.wikipedia.org/wiki/Horseshoe_kidney

... is a valvular heart disease that narrows the opening of the heart's tricuspid valve. It is a ... Rheumatic disease Carcinoid syndrome Pacemaker leads (complication) A mild diastolic murmur can be heard during auscultation ... Valvular heart disease, Chronic rheumatic heart diseases). ... Catheter Device Therapies for Heart Failure". Heart Failure in ... However, severe stenosis, or damage to other valves in the heart, may require surgical repair or replacement. The treatment is ...

https://en.wikipedia.org/wiki/Tricuspid_valve_stenosis

... is a valvular heart disease characterized by the narrowing of the opening of the mitral valve of the heart. It ... Other rare causes include mitral annular calcification, endomyocardial fibroelastosis, malignant carcinoid syndrome, systemic ... Chapter 1: Diseases of the Cardiovascular system > Section: Valvular Heart Disease in: Elizabeth D Agabegi; Agabegi, Steven S ... of mitral stenosis are due to disease in the heart secondary to rheumatic fever and the consequent rheumatic heart disease. ...

https://en.wikipedia.org/wiki/Mitral_stenosis

... hypertension Elevated cholesterol Tobacco CARCinoid: Cutaneous flushing Asthmatic wheezing Right sided valvular heart lesions ... Acute blood loss Bone marrow failure Chronic disease Destruction (hemolysis) ANEMIA: Anemia of chronic disease No folate or B12 ...

https://en.wikipedia.org/wiki/List_of_pathology_mnemonics

The drug is in decreasing use, as it was reported in 2003 to be associated with a form of heart disease called cardiac fibrosis ... including serotonin itself when elevated in the blood in carcinoid syndrome. Pergolide can rarely cause Raynaud's phenomenon. ... Parkinson's disease is associated with reduced dopamine activity in the substantia nigra of the brain. Pergolide acts on many ... for human use after several published studies revealed a link between the drug and increased rates of valvular heart disease. ...

https://en.wikipedia.org/wiki/Pergolide

ISBN 978-0-7817-7153-5. Chapter 1: Diseases of the Cardiovascular system > Section: Valvular Heart Disease Greenberg BH, Massie ... Other causes are mitral degenerative disease, severe calcification (elderly), congenital deformities, malignant carcinoid ... The most common causes are myxomatous degeneration (Barlow disease), ischemic heart disease, dilated cardiomyopathy, rheumatic ... "2017 ESC/EACTS Guidelines for the management of valvular heart disease". European Heart Journal. 38 (36): 2739-2791. doi: ...

https://en.wikipedia.org/wiki/Mitral_valve_replacement

... caffeine consumption carbon monoxide poisoning carcinoid tumor chronic obstructive pulmonary disease (COPD), especially ... abrupt cessation of physical exertion (resulting in heart output in excess of current muscular need for blood flow) abdominal ... Flushing is also a cardinal symptom of carcinoid syndrome-the syndrome that results from hormones (often serotonin or histamine ...

https://en.wikipedia.org/wiki/Flushing_(physiology)

As the disease progresses, a mixed pattern of obstruction and restriction may develop. In general the obstructive lung disease ... Upon surgical resection, histologically the nodules are found to be typical carcinoids or carcinoid tumorlets depending on size ... Pathology and Genetics of Tumours of the Lung, Pleura, Thymus and Heart. Lyon, France: IARC Press. Wirstschafter, E; Walts, A; ... The morbidity associated with DIPNECH is due to the associated obstructive lung disease. The lung disease tends to be slowly ...

https://en.wikipedia.org/wiki/Diffuse_idiopathic_pulmonary_neuroendocrine_cell_hyperplasia

... heart and lung disease. Gloria Jean, 92, American singer and actress (The Under-Pup, Pardon My Rhythm, Manhattan Angel), heart ... Ann Ireland, 65, Canadian novelist, carcinoid syndrome. Dominik Kalata, 93, Slovak Roman Catholic prelate, Titular Bishop of ... heart disease. Richard D. Alexander, 88, American evolutionary biologist. Ted Atkins, 60, British mountaineer, climbing ... heart attack. Kin Sugai, 92, Japanese actress (Godzilla, Dodes'ka-den, The Funeral), heart failure. Mohammed Awad al-Zayyud, 62 ...

https://en.wikipedia.org/wiki/Deaths_in_August_2018

... and heart disease. Quantitation of urinary 5-HIAA is the best test for carcinoid, but scrupulous care must be taken that ... Midgut carcinoids are most apt to produce carcinoid syndrome with 5-HIAA elevation. Patients with renal disease may have ... 5-HIAA may be normal with nonmetastatic carcinoid tumor and may be normal even with the carcinoid syndrome, particularly in ... Such patients include those with celiac disease, tropical sprue, Whipple disease, stasis syndrome, and cystic fibrosis. It is ...

https://en.wikipedia.org/wiki/5-Hydroxyindoleacetic_acid

Stage IV disease requires addition of cisplatin-based chemotherapy in addition to those in stage II and III. For those with ... It contains the heart, esophagus, trachea, thymus, and aorta. The most common mediastinal masses are neurogenic tumors (20% of ... Tonofibrils seen under electron microscopy can differentiate thymoma from other tumors such as carcinoid, Hodgkin's, and ... disease; (2) Teratoma and cyst. Many signs and symptoms of a mediastinal tumor do not distinguish between these two principal ...

https://en.wikipedia.org/wiki/Mediastinal_tumors

It can detect both intra and extra-adrenal disease. The imaging is highly sensitive and specific. Iobenguane concentrates in ... It also accumulates in norepinephrine transporters in adrenergic nerves in the heart, lungs, adrenal medulla, salivary glands, ... 2007). "Anatomic and functional imaging of metastatic carcinoid tumors". Radiographics. 27 (2): 455-77. doi:10.1148/rg. ... carcinoid tumors, neuroblastomas, and medullary thyroid cancer. Thyroid blockade with (nonradioactive) potassium iodide is ...

https://en.wikipedia.org/wiki/Iobenguane

... cell type 209 Neuroendocrine tumors 209.0 Malignant carcinoid tumors of the small intestine 209.1 Malignant carcinoid tumors of ... 202.5 Letterer-Siwe disease 202.6 Malignant mast cell tumors 202.7 Peripheral T-cell lymphoma 202.8 Other lymphomas 202.9 Other ... heart, and mediastinum 165 Malignant neoplasm of other and ill-defined sites within the respiratory system and intrathoracic ... poorly differentiated neuroendocrine carcinoma 209.4 Benign carcinoid tumors of the small intestine 209.5 Benign carcinoid ...

https://en.wikipedia.org/wiki/List_of_ICD-9_codes_140–239:_neoplasms

They are usually caused by the effect of a cancer on the part of the body where it is growing, although the disease can cause ... These clots may disrupt circulation locally or dislodge and travel to the heart, lungs, or brain, and may be fatal. Symptoms of ... Examples include the production of parathyroid hormones by parathyroid tumors or serotonin by carcinoid tumors. In these cases ... Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body ...

https://en.wikipedia.org/wiki/Cancer_signs_and_symptoms

... disease 10% of patients have extra-adrenal (paraganglioma) disease 10% of patients have inherited (familial disease) Despite ... An elevated heart rate (tachycardia) and the feeling of a racing heart (palpitations) may follow after initiating an alpha- ... "Neuroendocrine Cancer Survivor Featured on Discovery Fit & Health TV Show". Carcinoid Cancer Foundation. 2012-07-08. Retrieved ... "Rare Disease Day 2021 - 28 Feb". Rare Disease Day - 28 Feb 2021. Retrieved 2020-08-26. "Home". NORD (National Organization for ...

https://en.wikipedia.org/wiki/Pheochromocytoma

Congenital l Congenital heart block Congenital heart disease ptosis hypodontia craniostosis Congenital heart disease radio ... Carbohydrate deficient glycoprotein syndrome Carbon baby syndrome Carbonic anhydrase II deficiency Carcinoid syndrome Carcinoma ... Marie-Tooth disease type 1A Charcot-Marie-Tooth disease type 1B Charcot-Marie-Tooth disease type 1C Charcot-Marie-Tooth disease ... Marie-Tooth disease type 2C Charcot-Marie-Tooth disease type 2D Charcot-Marie-Tooth disease type 4A Charcot-Marie-Tooth disease ...

https://en.wikipedia.org/wiki/List_of_diseases_(C)

Furthermore, SNX8 study is motivated by its medical significance in relation to diseases such as Alzheimer's Disease, cancer, ... endometrial or carcinoid cancer presented low or any concentrations of SNX8. The rationale behind this differential phenotype ... one of the most common cyanotic congenital heart defects. Nevertheless, evidence demonstrates the existence of patients with ... "Beta-amyloid toxicity modifier genes and the risk of Alzheimer's disease". American Journal of Neurodegenerative Disease. 1 (2 ...

https://en.wikipedia.org/wiki/SNX8

"Carcinoid Tumors and Syndrome". The Lecturio Medical Concept Library. Retrieved 5 July 2021. "Acromegaly". NIDDK. April 2012. ... Somatostatin released in the pyloric antrum travels via the portal venous system to the heart, then enters the systemic ... It is also finding increased use in polycystic diseases of the liver and kidney. Lanreotide (Somatuline, Ipsen Pharmaceuticals ... most notably carcinoid syndrome. It is a long-acting analog of somatostatin, like octreotide. It is available in several ...

https://en.wikipedia.org/wiki/Somatostatin

Adult linear IgA disease Bullous pemphigoid Bullous lupus erythematosus Childhood linear IgA disease (chronic bullous disease ... Gottron's carcinoid papillomatosis, papillomatosis cutis carcinoides of Gottron-Eisenlohr) Patch blue nevus (acquired dermal ... epidermolysis bullosa Craniosynostosis-anal anomalies-porokeratosis syndrome Cockayne syndrome Colobomas of the eye-heart ... Weil's disease) Listeriosis Ludwig's angina Lupoid sycosis Lyme disease (Afzelius' disease, Lyme borreliosis) Lymphogranuloma ...

https://en.wikipedia.org/wiki/List_of_skin_conditions

Many patients with spider veins seek the assistance of physicians who specialize in vein care or peripheral vascular disease. ... radiation proctitis Chemotherapy Carcinoid syndrome Limited systemic sclerosis/scleroderma (a scleroderma sub-type) Chronic ... with foam sclerotherapy shows that the foam containing the irritating sclerosant quickly appears in the patient's heart and ... In men, they are related to high estrogen levels secondary to liver disease. Tempi syndrome Tobacco smoking Cutaneous ...

https://en.wikipedia.org/wiki/Telangiectasia

AGL Glycogen storage disease IV; 232500; GBE1 Glycogen storage disease IXc; 613027; PHKG2 Glycogen storage disease of heart, ... CPN1 Carcinoid tumors, intestinal; 114900; SDHD Cardiac arrhythmia, ankyrin-B-related; 600919; ANK2 Cardiac conduction defect, ... RNF212 Refsum disease; 266500; PEX7 Refsum disease; 266500; PHYH Refsum disease, infantile form; 266510; PEX26 Refsum disease, ... PSEN1 Alzheimer disease-10; 104300; AD10 Alzheimer disease-2; 104310; APOE Alzheimer disease-4; 606889; PSEN2 Alzheimer disease ...

https://en.wikipedia.org/wiki/List_of_OMIM_disorder_codes

... carcinoid syndrome, and hyperaldosteronism. The following diseases manifest by means of neurological dysfunction: Lambert-Eaton ... seen in acute heart failure or kidney failure, may result in death as well.[citation needed] Prostate cancer is the second most ... Disease Primers. 3: 17026. doi:10.1038/nrdp.2017.26. PMC 5901732. PMID 28492232. Hong MK, Kong J, Namdarian B, Longano A, ... The following diseases manifest by means of endocrine dysfunction: Cushing syndrome, syndrome of inappropriate antidiuretic ...

https://en.wikipedia.org/wiki/Paraneoplastic_syndrome

Price Thomas was also well known for heart surgery. He had been involved with the first resection of coarctation of the aorta ... The king honoured him with the KCVO, in December 1951, barely two months before he died from the effects of arterial disease. ... He was the first surgeon to do a bronchial sleeve resection, in 1947: the operation involved removing a bronchial carcinoid ... He became a consultant at the King Edward VII Sanatorium, Midhurst, and at the Royal National Hospital for Diseases of the ...

https://en.wikipedia.org/wiki/Clement_Price_Thomas

... in which there is enlargement and failure of the right side of the heart as a result of disease of the lungs. There are many ... Bronchiectasis secondary to a large carcinoid tumor (not shown) that was completely obstructing the bronchus proximally. ... In these diseases, the symptoms of bronchiectasis usually presents later in the disease course. Other autoimmune diseases such ... The disease affects between 1 per 1000 and 1 per 250,000 adults. The disease is more common in women and in the elderly. In a ...

https://en.wikipedia.org/wiki/Bronchiectasis

Alcohol or drug intoxication Cardiac arrhythmia Valvular heart disease Postprandial syndrome Hyperthyroidism Pheochromocytoma ... Hypoglycemia may occur in people with non-B cell tumors such as hepatomas, adrenocorticoid carcinomas, and carcinoid tumors. ... The glycogen storage diseases associated with hypoglycemia include type 0, type I, type III, and type IV, as well as Fanconi ... Severe disease of many organ systems can cause hypoglycemia as a secondary problem. Hypoglycemia is especially common in those ...

https://en.wikipedia.org/wiki/Hypoglycemia

Town Lawrence-Seip syndrome Lazarus syndrome Leaky gut syndrome Legg-Calvé-Perthes disease Legius syndrome Leiner's disease ... syndrome Hyperviscosity syndrome Hypohidrotic ectodermal dysplasia Hypoplastic left heart syndrome Hypoplastic right heart ... Cantú syndrome Capgras delusion Capgras syndrome Capillary leak syndrome Caplan's syndrome Carcinoid syndrome Cardiac syndrome ... VIP syndrome VIPoma Visual looming syndrome Vitreous touch syndrome Vogt-Koyanagi-Harada disease Von Hippel-Lindau disease ...

https://en.wikipedia.org/wiki/List_of_syndromes

... and may worsen disease outcomes in those with the earliest disease. In those with stage II disease, chemotherapy is usually ... while tumors infiltrating the area around the heart can cause fluid buildup around the heart, arrythmia, and heart failure. ... Rare subtypes include carcinoid tumors, bronchial gland carcinomas, and sarcomatoid carcinomas. Lung cancer staging is an ... heart, largest blood vessels that supply the heart, trachea, esophagus, or spine are designated T4. Lymph node staging depends ...

https://en.wikipedia.org/wiki/Lung_cancer

Slow heart rate, skin reactions such as pruritus, hyperbilirubinemia, hypothyroidism, dizziness and dyspnoea are also fairly ... Hofland, L. J.; Lamberts, S. W. (January 1996). "Somatostatin receptors and disease: role of receptor subtypes". Bailliere's ... diarrhea and flushing episodes associated with carcinoid syndrome, and diarrhea in people with vasoactive intestinal peptide- ... Texas Heart Institute Journal. 32 (3): 437-9. PMC 1336729. PMID 16392238. Siu SL, Lam DS (2006). "Spontaneous neonatal ...

https://en.wikipedia.org/wiki/Octreotide

A disease that was characterized by dermatitis of sunlight-exposed skin was described in Spain in 1735 by Gaspar Casal. He ... "Cholesterol Medications". American Heart Association. 10 November 2018. Retrieved 8 May 2020. Goodman, Louis S. (Louis Sanford ... Niacin synthesis is also deficient in carcinoid syndrome, because of metabolic diversion of its precursor tryptophan to form ... Hartnup disease is a hereditary nutritional disorder resulting in niacin deficiency. It is named after an English family with a ...

https://en.wikipedia.org/wiki/Vitamin_B3

John McCarthy, 84, American computer scientist, creator of LISP and the term AI, heart disease. Pat McNamara, 85, American ... Derrick Bell, 80, American law professor (Harvard University), originated critical race theory, carcinoid cancer. Anita Caspary ... Liz Anderson, 81, American country music singer-songwriter, complications from heart and lung disease. Mick Anglo, 95, British ... heart disease. Martin White, 102, Irish hurler. Winstone Zulu, 47, Zambian AIDS and tuberculosis activist. Sheila Allen, 78, ...

https://en.wikipedia.org/wiki/Deaths_in_October_2011

ISBN 1-4051-0386-8. Rosen CJ (2008-11-18). Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism. John ... 2007). "Anatomic and functional imaging of metastatic carcinoid tumors". Radiographics. 27 (2): 455-77. doi:10.1148/rg. ... such as the heart or the brain. A special type of gamma camera is the SPECT (Single Photon Emission Computed Tomography). ... It can also diagnose gallbladder diseases, e.g. bile leaks of biliary fistulas. In cholescintigraphy, the injected radioactive ...

https://en.wikipedia.org/wiki/Scintigraphy

Carcinoid syndrome - episodes of severe flushing precipitated by alcohol, stress and certain foods. May also be associated with ... Digestive diseases, Health in East Asia, Health effects of alcohol, Metabolic disorders, East Asia, East Asian people). ... accelerated heart rate, shortness of breath, throbbing headache, mental confusion and blurred vision). For measuring the level ... headaches and a fast heart rate. The condition may be also highly prevalent in some Southeast Asian and Inuit populations. The ...

https://en.wikipedia.org/wiki/Alcohol_flush_reaction

... as a biomarker in carcinoid heart disease and NETG1/G2 neuroendocrine Chromogranin A (CgA) as a biomarker in carcinoid heart ... Progression of carcinoid syndrome (CS) to carcinoid heart disease (CHD) is difficult to predict. This retrospective analysis ... Carcinoid heart disease; Carcinoid syndrome; Chromogranin A; Cromogranina A; Enfermedad cardiaca carcinoide; Neuroendocrine ... CgA has potential as a clinically useful biomarker in reporting disease status and predicting outcome in patients with CS and ...

https://pesquisa.bvsalud.org/portal/resource/pt/mdl-34736622

Carcinoid heart disease: The challenge of the unknown known. / Warner, Richard R.P.; Castillo, Javier G. In: Journal of the ... Carcinoid heart disease: The challenge of the unknown known. Journal of the American College of Cardiology. 2015 Nov 17;66(20): ... Warner, Richard R.P. ; Castillo, Javier G. / Carcinoid heart disease : The challenge of the unknown known. In: Journal of the ... Warner, R. R. P., & Castillo, J. G. (2015). Carcinoid heart disease: The challenge of the unknown known. Journal of the ...

https://scholars.mssm.edu/en/publications/carcinoid-heart-disease-the-challenge-of-the-unknown-known-2

Many patients with neuroendocrine tumour-related carcinoid syndrome treated with somatostatin analogues (SSA) wont achieve ... The impact on carcinoid heart disease, mesenteric fibrosis and other long-term complications of carcinoid syndrome as well as ... Carcinoid Right Heart Disease. Sanchez-Nadales A, Celis-Barreto V, Anampa-Guzman A, Salazar-Leon M, Contreras-Chavez P. Sanchez ... Telotristat ethyl: a new option for the management of carcinoid syndrome Angela Lamarca 1 , Jorge Barriuso 1 2 , Mairéad G ...

https://www.ncbi.nlm.nih.gov/pubmed/27817224

https://pubmed.ncbi.nlm.nih.gov/27817224/

Carcinoid heart disease without the carcinoid syndrome but with quadrivalvular regurgitation and unsuccessful operative ... Carcinoid heart disease.. Jaber WA; Klarich KW. Circulation; 2006 Feb; 113(7):e160-1. PubMed ID: 16490828. [No Abstract] [Full ... Carcinoid heart disease: diagnosis by two-dimensional echocardiography.. Howard RJ; Drobac M; Rider WD; Keane TJ; Finlayson J; ... Carcinoid heart disease: a Doppler echocardiographic report.. Marin-Huerta E; Navascues I; Palomeque CF; Nuñez A; Cobos MA; ...

https://pubmedhh.nlm.nih.gov/biomarkers/search.php?id=6206810&mod=related&page=1&outid=&proj=

Carcinoid Heart Disease (5) * Cardiac Conduction System Disease (1) * Cardiac Output, High (3) ... Articles by Disease Articles By Disease Bentham is offering subject-based scholarly content collections which are tailored to ...

https://benthamscience.com/alldiseases/258/cardiovascular%20disorders

Carcinoid Heart Disease C14.280.129 C14.280.104. Cardiac Output G9.330.553.400.280 G9.330.553.660.124. Cardiac Output, High ... Heart Murmurs C14.280.484.275. G9.330.553.400.515.500. Heart Rate G9.330.553.400.509 G9.330.553.660.500. Heart Rate, Fetal ... Hippel-Lindau Disease C10.562.400 C10.562.925. C14.907.77.350 C14.907.77.925. (Replaced for 2008 by von Hippel-Lindau Disease) ... Replaced for 2008 by Coronary Artery Disease). Coronary Disease C14.907.553.470.250 C14.907.585.250. Coronary Restenosis ...

https://decs.bvs.br/P/mnchg2008.htm

Carcinoid heart disease5), n (%). 10 (1.2%). n,5. Time from GEP-NET diagnosis until death or 31 Dec 2013 (years), mean (SD). ... had been diagnosed with carcinoid heart disease during the same time span. The median follow-up time was 2.93 years (range 0.01 ... would be earlier diagnosis and treatment of the disease due to presence of symptomatic disease in the form of carcinoid ... Long-term follow-up of a large series of patients with type 1 gastric carcinoid tumors: data from a multicenter study. Eur J ...

https://jcancer.org/v10p6876.htm

Tricuspid valve disease involves the atrioventricular valve apparatus that separates the right atrium (RA) from the right ... may be seen in most patients with carcinoid heart disease. For patients with TR caused by endocarditis, echocardiography may ... of Patients With Valvular Heart Disease provide recommendations for clinicians to diagnose and manage valvular heart disease, ... American Heart Association (AHA) Guidelines for the Management of Patients With Valvular Heart Disease. [12] ...

https://emedicine.medscape.com/article/351301-overview

GROSS: CARDIOVASCULAR: HEART: Carcinoid Heart Disease: Tricuspid valve. Powered by Piwigo ...

https://peir.path.uab.edu/library/picture.php?/2568/tags/9-cardiovascular/1592-carcinoid&slideshow=

Carcinoid heart disease occurs in more than half of the patients with the carcinoid syndrome. Patients with carcinoid heart ... Carcinoid, Carcinoid heart disease, Carcinoid syndrome, Neuroendocrine tumor Persistent URL doi.org/10.1159/000461583, hdl. ... Neuroendocrine tumors of the small intestine are the most common causes of the carcinoid syndrome. ... aims at controlling the excessive hormonal output and symptoms related to the carcinoid syndrome and at preventing a carcinoid ...

https://repub.eur.nl/pub/108320

Cardiovascular Diseases [C14] * Heart Diseases [C14.280] * Arrhythmias, Cardiac [C14.280.067] * Carcinoid Heart Disease [ ... Carcinoid Heart Disease Preferred Concept UI. M0003420. Scope Note. Cardiac manifestation of gastrointestinal CARCINOID TUMOR ... Malignant Carcinoid Syndrome [C04.557.465.625.650.200.500] * Carcinoid Heart Disease [C04.557.465.625.650.200.500.205] ... Malignant Carcinoid Syndrome [C04.557.470.200.025.200.500] * Carcinoid Heart Disease [C04.557.470.200.025.200.500.205] ...

https://meshb.nlm.nih.gov/record/ui?ui=D002275

Specific issues for carcinoid patients, such as carcinoid crisis and carcinoid heart disease, are addressed. ... carcinoid blogs, carcinoid cancer, carcinoid cancer awareness, carcinoid patient stories, living with cancer, Maria Gonzalez, ... "My experience with carcinoid cancer began in January 1995, although I did not know it at the time. I had a heart attack ... Categories: carcinoid cancer, neuroendocrine cancer. Tags: But You Look So Good, But You Look So Good . . .Stories by Carcinoid ...

https://www.carcinoid.org/2013/06/28/but-you-look-so-good-stories-by-carcinoid-cancer-survivors/

... those with carcinoid heart disease, pregnant women receiving cancer therapy, as well as those with cardiac implantable ... Best Practice Treatment and Management of Patients with Type 2 Diabetes, Cardiovascular Disease, and Heart Failure ... BARCELONA - Cardiovascular disease risk factors, as well as established disease, in patients undergoing cancer therapy can be ... but they have all these pre-existing heart risk factors, whether as confirmed disease or just the risk factors associated with ...

https://www.medscape.com/viewarticle/980044

Carcinoid heart disease (tricuspid valve insufficiency). * Vermiform Appendix. location. arises from. rich in? ... What is Diverticular disease?. What side? what location in bowel?. What is the pathogenesis? ...

https://freezingblue.com/flashcards/47433/preview/path-block-3-gie

Carcinoid Heart Disease/complications; Carcinoid Heart Disease/drug therapy*; Carcinoid Heart Disease/genetics; Carcinoid Heart ... could overcome a number of resistance mechanisms in tumors and delay cardiac carcinoid disease. We performed preclinical ... and common diseases to help prevent disease and improve human health. ... In conclusion, in the majority of pNETs that progress on rapalogs, it is possible to reduce disease progression using an mTORKi ...

https://tools.niehs.nih.gov/portfolio/index.cfm?do=portfolio.publicationDetail&id=3353107

Carcinoid Heart Diseases. Heart Disease, Carcinoid. Heart Diseases, Carcinoid. Tree number(s):. C04.557.465.625.650.200.500.205 ... Carcinoid Heart Disease Entry term(s). Carcinoid Heart Diseases Heart Disease, Carcinoid Heart Diseases, Carcinoid ... Carcinoid Heart Disease - Preferred Concept UI. M0003420. Scope note. Cardiac manifestation of gastrointestinal CARCINOID TUMOR ... search MALIGNANT CARCINOID SYNDROME 1966-74. History Note:. 91(75)(64-72); was see under MALIGNANT CARCINOID SYNDROME 1964-90 ( ...

https://decs.bvsalud.org/en/ths/resource/?id=2318&filter=ths_exact_term&q=ENFERMEDAD+CARDIACA+CARCINOIDE

The relationship between carcinoid syndrome and carcinoid heart disease - a condition that affects the heart valves and results ... Order Your Copy of the Medifocus Guidebook on Carcinoid Tumors Today!. The Medifocus Guidebook on Carcinoid Tumors (166 pages; ... Important questions to ask your doctor about carcinoid tumors.. A "One-of-a-Kind" Reference Guidebook on Carcinoid Tumors that ... Neuroendocrine tumors (NETs) include both carcinoid tumors and pancreatic endocrine tumors (PETs). Carcinoid tumors represent ...

https://parkinsonsdisease-guidebook.com/landing.php?gid=GS019&a=a

https://meshb-prev.nlm.nih.gov/record/ui?ui=D002275

Appetite suppressants and valvular heart disease. Seghatol, F. F. & Rigolin, V. H., Sep 2002, In: Current Opinion in Cardiology ... Cirrhotic heart problems. Cohen-Solal, A., Beauvais, F., Seghatol, F. & Durand, F., Nov 2003, In: Hepato-Gastro. 10, 6, p. 435- ... Heart and liver cirrhosis. Cohen-Solal, A., Seghatol, F. & Durand, F., Nov 2007, In: Medecine Therapeutique - Cardio. 3, 6, p. ... Hasnie, A. A., Miller, N. & Seghatol-Eslami, F., Dec 1 2021, In: European Heart Journal - Case Reports. 5, 12, ytab507.. ...

https://profiles.wustl.edu/en/persons/frank-seghatol-eslami/publications/

... b heart disease carcinoid heart disease coronary heart disease heart disease hyperkinetic heart disease ischemic heart disease ... heart disease rheumatic heart disease round heart disease thyrotoxic heart disease hypertensive heart disease mulberry heart ... heart disease arteriosclerotic heart disease noncyanotic congenital heart disease valvular heart disease coronary heart disease ... congenital heart disease complex congenital heart disease carcinoid valvular heart disease chronic valvular heart disease ...

https://lhncbc.nlm.nih.gov/LSG/Projects/LexAccess/current/docs/designDoc/UDF/options/baseContain.html

International Journal of Rare Diseases and Orphan Drugs ISSN : 2576-0092. Launched : 2016 ... and potential heart failure. However, these symptoms do not occur in the absence of metastasis [1,4] which is typically to the ... The diagnosis of a carcinoid tumor is rarely thought of in the absence of carcinoid syndrome symptoms of which include flushing ... Carcinoid Tumors. Am Fam Physician. 2006; 74: 429-434.. 4. Ruoff C, Hanna L, Zhi W, Shahzad G, Gotlieb V, Saif MW. Cancers of ...

https://www.jscimedcentral.com/jounal-article-info/Archives-of-Emergency-Medicine-and-Critical-Care--/Carcinoid-Tumor-of-the--Appendix-in-an-Adolescent--Female-6889

Carcinoid Heart Disease : What you need to know about it January 16, 2022 ...

https://www.setuppost.com/category/business/

carcinoid tumors;. *chronic ischemic heart disease (I20, I25) reported as "due to" any neoplasm; ... Parkinson Disease (G20). Advanced Parkinson Disease (G2000). Grave Parkinson Disease (G2000). Severe Parkinson Disease (G2000) ... Code to the residual category for ischemic heart disease (I259).. *When different diseases or conditions are classifiable to ... rheumatic fever (I00-I02) or rheumatic heart disease (I05-I09) reported as "due to" any disease other than scarlet fever (A38 ...

https://www.cdc.gov/nchs/nvss/manuals/2019/2a-sectioniii-2019.htm

... accredited medical education programs on NET disease that are developed by leading NET experts and designed exclusively for ... Carcinoid Heart Disease. * *Screening, Diagnosis, and Management. Shaheeda Ahmed, MDCM, FRCPC, FACC, Assistant Professor, ... As this is a rare disease, clinicians often do not know how to implement the appropriate care plan and until the last ten years ... Neuroendocrine tumors (NET) are considered to be a rare disease although the frequency of diagnosis has increased over the last ...

https://members.nanets.net/toronto

CARCINOID HEART DISEASE. *INFECTIVE ENDOCARDITIS. *NON-INFECTIVE ENDOCARDITIS (NBTE - Non Bacterial Thrombotic Endocarditis) ... RHEUMATIC FEVER & RHEUMATIC HEART DISEASE. *VALVULAR HEART DISEASE & MURMURS. *CARDIOVASCULAR DISEASE & OBESITY; NUTRITION & ...

https://www.medstudentnotes.com/collections/anatomy-physiology-pathology-notes/products/cardiovascular-system-notes

The Mitral Valve Disease Program treats patients with mitral valve disease, including mitral stenosis, mitral regurgitation and ... Home / Baylor Scott & White Heart and Vascular Hospital / Fort Worth / Valve Disorders Center / Mitral Valve Disease ... The Mitral Valve Disease Program in Fort Worth, part of the Valve Disorders Center, treats heart patients with mitral valve ... Mitral valve disease intervention at the earliest stage of the heart condition is important. Early diagnosis can lead to an ...

https://salud.bswhealth.com/heart-and-vascular-hospital/fort-worth/valve-disorders-center/mitral-valve-disease

Hallmark of carcinoid heart disease is: endocardial fibrosis involving the right heart, in particular the tricuspid valve and ... Malignant carcinoid syndrome: hepatomegaly, diarrhea, flushing, right heart valvular failure, asthma, malabsorption and ... carcinoid with liver mets with octreotide +/- alpha-INF, hepatic artery embolization, chemo., resection; Bronchial carcinoids ... recurrent disease, skin, bone nerve or extraparotid involvement, positive nodes, gross residual or unresectable disease ...

https://www.absitereview.com/resources/quick-surgery-reviews/

https://decs2008.bvsalud.org/P/mnchg2008.htm

Metastatic small bowel neuroendocrine tumour with bilateral carcinoid heart disease. BMJ Case Reports 2016; doi:10.1136/bcr- ... 7. Metastatic small bowel neuroendocrine tumour with bilateral carcinoid heart disease. British Endocrine Society, UK 2015 8. ... Thyrotoxicosis factitia masquerading as recurrent Graves disease: Endogenous antibody immunoassay interference, a pitfall for ...

https://kmchhospitals.com/endocrionology/dr-vidhya-rajeev-jahagirdar-m-b-b-s-mrcpinternal-medicinemrcpdiabetes-endocrinology/

Chromogranin A (CgA) as a biomarker in carcinoid heart disease and NETG1/G2 neuroendocrine neoplasms of the small intestine (SI-NENs) related carcinoid syndrome. (bvsalud.org)
Progression of carcinoid syndrome (CS) to carcinoid heart disease (CHD) is difficult to predict. (bvsalud.org)
Telotristat ethyl is a tryptophan hydroxylase inhibitor, developed for the treatment of carcinoid syndrome. (nih.gov)
Areas covered: This review summarises the evidence supporting the role of telotristat ethyl in the management of carcinoid syndrome. (nih.gov)
1. The tricuspid valve in carcinoid syndrome. (nih.gov)
2. [Echocardiographic detection of tricuspid insufficiency in carcinoid heart syndrome - case report]. (nih.gov)
3. [The echocardiogram in the carcinoid heart syndrome. (nih.gov)
11. [Tricuspid and pulmonary percutaneous valvulopathy in the cardiopathy of the carcinoid syndrome. (nih.gov)
15. Oat cell carcinoma of the bronchus and the carcinoid syndrome. (nih.gov)
18. Carcinoid heart disease without the carcinoid syndrome but with quadrivalvular regurgitation and unsuccessful operative intervention. (nih.gov)
20. [Atypical presentation of a carcinoid syndrome]. (nih.gov)
In patients with carcinoid syndrome, endomyocardial fibrosis may lead to obstruction of RV inflow, resulting in a clinical presentation similar to that of TS. (medscape.com)
Neuroendocrine tumors of the small intestine are the most common causes of the carcinoid syndrome. (eur.nl)
Carcinoid heart disease occurs in more than half of the patients with the carcinoid syndrome. (eur.nl)
Treatment with long-acting somatostatin analogs aims at controlling the excessive hormonal output and symptoms related to the carcinoid syndrome and at preventing a carcinoid crisis during interventions. (eur.nl)
The medications prescribed by my primary physician masked symptoms we now recognize are related to carcinoid syndrome. (carcinoid.org)
Carcinoid tumors represent the largest number of neuroendocrine tumors and pose a significant challenge to the clinician because they produce a unique clinical syndrome. (parkinsonsdisease-guidebook.com)
Over the years it became clear that carcinoid tumors can be quite aggressive, can metastasize, and can cause carcinoid syndrome . (parkinsonsdisease-guidebook.com)
A detailed overview of a condition known as carcinoid syndrome that describes a combination of symptoms that result from hormone-like substances, such as serotonin, gastrin, and ACTH, that are produced by some carcinoid tumors. (parkinsonsdisease-guidebook.com)
The relationship between carcinoid syndrome and carcinoid heart disease - a condition that affects the heart valves and results in inefficient pumping of blood from the heart to other areas of the body. (parkinsonsdisease-guidebook.com)
A comprehensive discussion of the relationship between an inherited condition called Multiple Endocrine Neoplasm Syndrome, Type 1 and the risk for developing certain types of carcinoid tumors. (parkinsonsdisease-guidebook.com)
The histopathologic features were similar to those observed in carcinoid-induced valvular disease, a serotonin-related syndrome. (cdc.gov)

13. [Isolated carcinoid tumor of the ovary disclosed by tricuspid insufficiency]. (nih.gov)
Cardiac manifestation of gastrointestinal CARCINOID TUMOR that metastasizes to the liver. (nih.gov)
The age at diagnosis varies somewhat among specific tumor locations but typically, most people diagnosed with carcinoid tumor are in their 50s. (parkinsonsdisease-guidebook.com)
The most common site of carcinoid tumor occurrence for men is in the small intestines and the appendix for women. (parkinsonsdisease-guidebook.com)
If you or a loved one has been diagnosed with a carcinoid tumor, it's critical to learn everything you possibly can about this condition so that you can make informed decisions about your treatment. (parkinsonsdisease-guidebook.com)
The risk factors that can increase a person's chances for developing a carcinoid tumor. (parkinsonsdisease-guidebook.com)
Carcinoid tumor is the most common tumor of the appendix. (jscimedcentral.com)
Nassif D, Sethuraman U (2016) Carcinoid Tumor of the Appendix in an Adolescent Female. (jscimedcentral.com)
Locally advanced cancer seen in patients with primary tumors 5cm (T3 lesion), fixed or matted axillary nodes (N2 disease), primary tumor fixed to the chest wall (T4 lesion) and inflammatory breast cancer. (absitereview.com)
Surgical history includes a small bowel resection for ileal carcinoid tumor with metastasis to the liver and hepatic arterial embolization 16 years prior. (rroij.com)

Neuroendocrine tumors (NETs) include both carcinoid tumors and pancreatic endocrine tumors (PETs). (parkinsonsdisease-guidebook.com)
Because the majority of neuroendocrine tumors of the pancreas and carcinoid tumors that involve the wall of the gut have similar biological characteristics, the approach to diagnosis and treatment can be applied broadly to all classes of NETs. (parkinsonsdisease-guidebook.com)
There are many types of tumors that arise from the neuroendocrine system of which carcinoid tumors are the most common. (parkinsonsdisease-guidebook.com)
Carcinoid tumors were initially identified in 1888 and were thought to clinically and histologically (cellular appearance under a microscope) resemble carcinoma cells (highly malignant cancer cells) but behave in a more benign fashion than true cancer cells. (parkinsonsdisease-guidebook.com)
Most carcinoid tumors are now known to be slow growing malignant tumors that have their own specific biological and clinical characteristics. (parkinsonsdisease-guidebook.com)
Carcinoid tumors are in general quite rare and occur in approximately 2.5-5 per 100,000 people. (parkinsonsdisease-guidebook.com)
It is probable that more people may actually have carcinoid tumors but because carcinoids are often asymptomatic, an individual may never know that a carcinoid has developed. (parkinsonsdisease-guidebook.com)
Carcinoid tumors are more prevalent among African-American males (approximately 4.5 per 100,000 people) than among Caucasian males (approximately 2.5 per 100,000 people). (parkinsonsdisease-guidebook.com)
That's why we created the Medifocus Guidebook on Carcinoid Tumors , a comprehensive 166 page patient Guidebook that contains vital information about carcinoid tumors that you won't find anywhere in a single source. (parkinsonsdisease-guidebook.com)
The underlying causes of carcinoid tumors. (parkinsonsdisease-guidebook.com)
Carcinoid tumors arise from neuroendrocrine cells in the foregut, midgut and hindgut with the midgut being the most common site for these tumors. (jscimedcentral.com)
It is estimated that carcinoid tumors have a prevalence worldwide among all population of 1 to 2 per 100,000 although it may be higher as many cases are asymptomatic and may go unnoticed [3,4]. (jscimedcentral.com)
Neuroendocrine tumors (NET) are considered to be a rare disease although the frequency of diagnosis has increased over the last ten years. (nanets.net)

Surgical treatment remains the standard of care, but tricuspid valve disease continues to have one of the highest death rates among all cardiac valve-related procedures, and a broad range of patients still do not receive effective therapy for tricuspid valve disease in contemporary clinical practice. (medscape.com)
[ 6 ] Echocardiography permits assessment of the dimensions of cardiac chambers, determination of RV and pulmonary pressures, and delineation of associated valvular diseases. (medscape.com)
Computed tomography (CT) scans of the heart are rarely needed to delineate structural cardiac abnormalities. (medscape.com)
The tricuspid valve has always been considered less relevant than the left-side valves of the heart, but this "forgotten valve" still represents a great challenge for cardiac surgeons, especially in the most difficult symptomatic scenarios. (medscape.com)
Interventional cardiologists and cardiac surgeons on the medical staff treat both degenerative mitral valve disease and functional mitral valve conditions. (bswhealth.com)
These services may include cardiac 3-D computed tomography (CT), cardiac 3-D imaging, cardiac echo, cardiac MRI, heart catheterization, pulmonary function testing (PFT), and vascular ultrasound. (bswhealth.com)
Because symptoms frequently occur relatively late during the course of valvular incompetence, the prevalence of valve lesions was assessed for patients who were exposed to these drugs but who had no obvious history of cardiac disease or cardiac symptoms. (cdc.gov)
Combined cardiac valvular disease and pulmonary hypertension appear to occur frequently in patients receiving fen-phen, and more autopsy cases of patients with a history of fen-phen usage are warranted to document the frequency of combined cardiac valvular disease and pulmonary hypertension in the United States. (the-medical-dictionary.com)
Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION. (harvard.edu)
Aortic Valve Calcium in Relation to Subclinical Cardiac Dysfunction and Risk of Heart Failure. (harvard.edu)

This may result from CONGENITAL HEART DEFECTS , predisposing heart diseases, complications of surgery, or HEART NEOPLASMS . (nih.gov)

The guidelines were presented at the European Society of Cardiology (ESC) Congress 2022 on August 27, and published simultaneously in the European Heart Journal . (medscape.com)

Medical history included moderate ischemic heart disease. (rroij.com)

curative surgery should be considered even in the case of metastatic disease, when possible. (jcancer.org)
Metastatic small bowel neuroendocrine tumour with bilateral carcinoid heart disease. (kmchhospitals.com)

CgA has potential as a clinically useful biomarker in reporting disease status and predicting outcome in patients with CS and with CHD. (bvsalud.org)
Therefore, several alternative, less-invasive technologies for treating patients with severe, native tricuspid valve disease at high surgical risk have been developed, with promising early results. (medscape.com)
Most patients with rheumatic tricuspid valve disease present with TR or a combination of stenosis and regurgitation. (medscape.com)
These tests provide assistance with timing and guidance during intervention for patients with tricuspid valve disease. (medscape.com)
[ 7 , 10 ] Patients who present with congestive heart failure may require assessment of tricuspid valve and LV function through a first-pass technique (ie, multiple-gated acquisition [MUGA] scanning). (medscape.com)
Tricuspid valve disease affects millions of patients worldwide. (medscape.com)
The 2020 American College of Cardiology (ACC)/American Heart Association (AHA) Guidelines for the Management of Patients With Valvular Heart Disease provide recommendations for clinicians to diagnose and manage valvular heart disease, as well as supporting documentation. (medscape.com)
In evaluating patients with valvular heart disease, findings on history and physical examination should be correlated with the results of noninvasive tests (ie, ECG, chest x-ray, transthoracic echocardiogram). (medscape.com)
Patients with carcinoid heart disease who need to undergo surgery should also undergo preoperative evaluation by an expert cardiologist. (eur.nl)
Specific issues for carcinoid patients, such as carcinoid crisis and carcinoid heart disease, are addressed. (carcinoid.org)
BARCELONA - Cardiovascular disease risk factors, as well as established disease, in patients undergoing cancer therapy can be safely managed to minimize cancer therapy-related cardiovascular toxicity (CVR-CVT), conclude the first cardio-oncology guidelines from the European Society of Cardiology. (medscape.com)
It is through convening professionals in the areas of oncology, gastroenterology, pulmonology, surgery, radiology and allied fields that the awareness and understanding of NET diseases will expand, resulting in better treatment for NET patients. (nanets.net)
The Mitral Valve Disease Program in Fort Worth, part of the Valve Disorders Center , treats heart patients with mitral valve disease, including mitral stenosis, mitral regurgitation and mitral valve prolapse. (bswhealth.com)
Advanced diagnostic testing and imaging services for patients with mitral valve heart conditions allow physicians to develop a personalized diagnostic and treatment plan. (bswhealth.com)
Carcinoid Heart Disease in Patients with Advanced Midgut NETs - E. (cor2ed.com)
Dapagliflozin and All-Cause Hospitalizations in Patients With Heart Failure With Preserved Ejection Fraction. (harvard.edu)
ECG-guided non-invasive estimation of pulmonary congestion in patients with heart failure. (harvard.edu)
and 4) access to information related to rare diseases for basic and clinical researchers, academic and practicing physicians, patients, and the lay public. (nih.gov)

4. [The tricuspid valve in carcinoid cardiopathy: characteristic echocardiographic aspects]. (nih.gov)
10. Quadruple valve involvement in a patient with severe carcinoid heart disease. (nih.gov)
16. Tricuspid and mitral valve carcinoid disease in the setting of a patent foramen ovale. (nih.gov)
Tricuspid valve disease, particularly tricuspid regurgitation, is a highly prevalent condition with a complex pathophysiology and long-term adverse consequences. (medscape.com)
Although historically neglected, tricuspid valve disease has gained increasing recognition, with important advances in assessment and management of this disorder since the year 2000. (medscape.com)
Tricuspid valve disease involves the atrioventricular valve apparatus that separates the right atrium (RA) from the right ventricle (RV). (medscape.com)
Isolated tricuspid valve disease is rare. (medscape.com)
Rheumatic TS does not occur as an isolated lesion, but it often accompanies mitral and aortic valve disease. (medscape.com)
Carcinoid heart disease (tricuspid valve insufficiency). (freezingblue.com)
Mitral valve disease intervention at the earliest stage of the heart condition is important. (bswhealth.com)
Early intervention for mitral valve disease could also reduce the risk of stroke for the heart patient. (bswhealth.com)
Although valvular lesions were observed on both sides of the heart, a left-sided valve was affected in all cases. (cdc.gov)
Heart valve damage and pulmonary hypertension, severe enough to cause permanent disability or death have been seen with phentermine alone. (the-medical-dictionary.com)

She was awarded The Society for Endocrinology Clinical Trust Research Fellowship and obtained a PhD in Professor Newell-Prices' laboratory, focussing on RNA interference as a Therapy for Cushing's Disease, leading to a patent and orphan drug designation. (cor2ed.com)
Department of Clinical Biochemistry (Vascular Disease Prevention Clinic), Royal Free Hospital and Royal Free University College Medical School, London, UK. (hellenicjcardiol.com)
Clinical profiling of end-stage heart failure with preserved ejection fraction: The National Readmission Database. (harvard.edu)
Clinical data management for efficient data collection as well as data mining and data sharing across rare diseases will be addressed in the DMCC application. (nih.gov)
This Funding Opportunity Announcement (FOA) invites applications for the Rare Diseases Clinical Research Consortia (RDCRC) component of the Rare Diseases Research Network (RDCRN). (nih.gov)
Clinical data management for efficient data collection as well as data mining and data sharing will be addressed through the Data Management and Coordinating Center (DMCC) component of the Rare Diseases Clinical Research Network (RDCRN). (nih.gov)

Many recommendations from earlier valvular heart disease guidelines have been updated with new evidence and newer options for diagnosis and treatment of valvular heart disease. (medscape.com)
On July 8, 1997, 24 cases of valvular heart disease in women who had been treated with fenfluramine and phentermine were publicly reported (1). (cdc.gov)
Fenfluramine was withdrawn from the U.S. market in 1997 after reports of valvular heart disease and pulmonary hypertension. (the-medical-dictionary.com)

Predictors of Human Milk Feeding and Direct Breastfeeding for Infants with Single Ventricle Congenital Heart Disease: Machine Learning Analysis of the National Pediatric Cardiology Quality Improvement Collaborative Registry. (cdc.gov)

Lyon said that the "most famous one" is trastuzumab, a monoclonal antibody that is used to treat HER2-positive breast cancer but that also causes left ventricular impairment "in about 15% to 20% of the women taking it and can cause severe heart failure if it is missed. (medscape.com)

We're doing a lot of surveillance because one of the big advantages of cardio-oncology is we know when someone is about to get treated," Lyon, from the National Heart and Lung Institute, Imperial College London, and Cardio-Oncology Service, Royal Brompton Hospital, London, said. (medscape.com)
Carcinoid lung cancer is more common in Caucasians than in African-American, Asian-Americans, or Hispanic/Latinos. (parkinsonsdisease-guidebook.com)

Pathology of the tissue revealed it was carcinoid. (carcinoid.org)

The author, Maria Gonzalez , is both a breast cancer and carcinoid survivor. (carcinoid.org)
My experience with carcinoid cancer began in January 1995, although I did not know it at the time. (carcinoid.org)
Believing that every life story should have a moral, or at least a purpose, here is my encouragement to anyone reading this and trying to learn more about carcinoid cancer. (carcinoid.org)
that the aim of the guideline was to "personalize the decision-making of a patient with cancer who has cardiovascular disease or is at risk of developing it from their treatment…because it's not one size fits all. (medscape.com)
He said that one of main drivers is modifiable factors, such as smoking, obesity, and inactivity, which increase the risk for both cancer and cardiovascular disease. (medscape.com)
Combined with the ageing population, the result is that "not only are many more people being diagnosed with cancer, because they're living longer, but they have all these pre-existing heart risk factors, whether as confirmed disease or just the risk factors associated with that," he said. (medscape.com)
Crucially, the impact of cancer therapy on cardiovascular risk is dependent on several factors, such as patient age, cancer history, pre-existing cardiovascular risk factors or cardiovascular disease, and pervious cardiotoxic cancer therapy. (medscape.com)

This retrospective analysis evaluates the use of chromogranin A (CgA), a biomarker widely used in the diagnosis of neuroendocrine tumours (NET), in monitoring CS and disease progression . (bvsalud.org)
9. Two-dimensional echocardiography in the diagnosis of carcinoid heart disease. (nih.gov)
14. Carcinoid heart disease: diagnosis by two-dimensional echocardiography. (nih.gov)
In addition, experts in the field of NET disease have continued to develop strategies to improve diagnosis, treatment and management of NET cancers. (nanets.net)
Early diagnosis can lead to an improved lifestyle, potentially lead to decreased dependence on blood thinners and could preserve heart function. (bswhealth.com)

Anaemia in Chronic Heart Failure: Is There a Rationale to Treat? (hellenicjcardiol.com)

6. Echocardiographic manifestations of carcinoid heart disease. (nih.gov)
7. Echocardiographic features of carcinoid heart disease. (nih.gov)
8. Cross sectional echocardiographic feature in carcinoid heart disease. (nih.gov)
17. Carcinoid heart disease: a Doppler echocardiographic report. (nih.gov)

rheumatic fever (I00-I02) or rheumatic heart disease (I05-I09) reported as "due to" any disease other than scarlet fever (A38), streptococcal septicemia (A40. (cdc.gov)

12. Do indole markers predict carcinoid heart disease? (nih.gov)

Cardiopulmonary arrest developed during right-heart catheterization, and she died 3 days later. (the-medical-dictionary.com)

I had a heart attack followed by a couple of small strokes. (carcinoid.org)

Compression of the heart by accumulated fluid ( PERICARDIAL EFFUSION ) or blood ( HEMOPERICARDIUM ) in the PERICARDIUM surrounding the heart. (nih.gov)

Allied to that, there's been an improvement in treating cardiovascular diseases in people in their 40s, 50s, and 60s, so they're surviving their heart failure, myocardial infarction, atrial fibrillation to develop cancers in later life. (medscape.com)
Heart Failure" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. (harvard.edu)
This graph shows the total number of publications written about "Heart Failure" by people in Harvard Catalyst Profiles by year, and whether "Heart Failure" was a major or minor topic of these publication. (harvard.edu)
Below are the most recent publications written about "Heart Failure" by people in Profiles. (harvard.edu)
Indirect epigenetic testing identifies a diagnostic signature of cardiomyocyte DNA methylation in heart failure. (harvard.edu)

As this is a rare disease, clinicians often do not know how to implement the appropriate care plan and until the last ten years, there was great variability in terms of treatment. (nanets.net)

Anatomy4

Diseases6

Chemicals and Drugs1

Analytical, Diagnostic and Therapeutic Techniques and Equipment2

Carcinoid heart disease from ovarian primary presenting with acute pericarditis and biventricular failure. (1/47)

Balloon pulmonary valvuloplasty in carcinoid syndrome. (2/47)

Tricuspid and pulmonary valve involvement in carcinoid disease. (3/47)

Perianaesthetic risks and outcomes of abdominal surgery for metastatic carcinoid tumours. (4/47)

Surgical management of left-sided carcinoid heart disease. (5/47)

Carcinoid heart disease: successful tricuspid valve replacement. (6/47)

Cardiovascular abnormalities in patients with a carcinoid syndrome. (7/47)

Echocardiographic diagnosis in carcinoid heart disease. (8/47)

Carcinoid Heart Disease

Malignant Carcinoid Syndrome

Carcinoid Tumor

Tricuspid Valve Stenosis

Heart Valves

Tricuspid Valve Insufficiency

Heart Valve Diseases

Tricuspid Valve

Hydroxyindoleacetic Acid

Pulmonary Valve

Bioprosthesis

Echocardiography

Heart

Carcinoid heart disease from ovarian primary presenting with acute pericarditis and biventricular failure. (1/47)

Balloon pulmonary valvuloplasty in carcinoid syndrome. (2/47)

Tricuspid and pulmonary valve involvement in carcinoid disease. (3/47)

Perianaesthetic risks and outcomes of abdominal surgery for metastatic carcinoid tumours. (4/47)

Surgical management of left-sided carcinoid heart disease. (5/47)

Carcinoid heart disease: successful tricuspid valve replacement. (6/47)

Cardiovascular abnormalities in patients with a carcinoid syndrome. (7/47)

Echocardiographic diagnosis in carcinoid heart disease. (8/47)

Carcinoid

Valvular heart disease

Carcinoid syndrome

Cardiac fibrosis

Barry A. Love

Jonathan L. Halperin

Neuroendocrine tumor

Pulmonary valve stenosis

Atrial septal defect

List of MeSH codes (C04)

Pulmonary insufficiency

Tricuspid regurgitation

Restrictive cardiomyopathy

Deaths in May 2014

Small intestine neuroendocrine tumor

Horseshoe kidney

Tricuspid valve stenosis

Mitral stenosis

List of pathology mnemonics

Pergolide

Mitral valve replacement

Flushing (physiology)

Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia

Deaths in August 2018

5-Hydroxyindoleacetic acid

Mediastinal tumors

Iobenguane

List of ICD-9 codes 140-239: neoplasms

Cancer signs and symptoms

Pheochromocytoma

List of diseases (C)

SNX8

Somatostatin

List of skin conditions

Telangiectasia

List of OMIM disorder codes

Paraneoplastic syndrome

Clement Price Thomas

Bronchiectasis

Hypoglycemia

List of syndromes

Lung cancer

Octreotide

Vitamin B3

Deaths in October 2011

Scintigraphy

Alcohol flush reaction

Chromogranin A (CgA) as a biomarker in carcinoid heart disease and NETG1/G2 neuroendocrine neoplasms of the small intestine (SI...

Carcinoid heart disease: The challenge of the unknown known<...

Telotristat ethyl: a new option for the management of carcinoid syndrome - PubMed

Telotristat ethyl: a new option for the management of carcinoid syndrome - PubMed

Biomarkers Search

Article By Diseases | Bentham Science

MESH TREE NUMBER CHANGES - 2008 MeSH

Treatment Patterns and Survival among Patients with Metastatic Gastroenteropancreatic Neuroendocrine Tumours in Sweden - a...

Tricuspid Valve Disease Imaging: Practice Essentials, Tricuspid stenosis, Tricuspid regurgitation

00002307 | PEIR Digital Library

RePub, Erasmus University Repository: ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors: Pre- A...

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