Ornithine Carbamoyltransferase
Ornithine Carbamoyltransferase Deficiency Disease
An inherited urea cycle disorder associated with deficiency of the enzyme ORNITHINE CARBAMOYLTRANSFERASE, transmitted as an X-linked trait and featuring elevations of amino acids and ammonia in the serum. Clinical features, which are more prominent in males, include seizures, behavioral alterations, episodic vomiting, lethargy, and coma. (Menkes, Textbook of Child Neurology, 5th ed, pp49-50)
Carboxyl and Carbamoyl Transferases
Carbamyl Phosphate
Carbamoyl-Phosphate Synthase (Ammonia)
Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing)
Transferases
Transferases are enzymes transferring a group, for example, the methyl group or a glycosyl group, from one compound (generally regarded as donor) to another compound (generally regarded as acceptor). The classification is based on the scheme "donor:acceptor group transferase". (Enzyme Nomenclature, 1992) EC 2.
Aspartate Carbamoyltransferase
Carbamates
Derivatives of carbamic acid, H2NC(=O)OH. Included under this heading are N-substituted and O-substituted carbamic acids. In general carbamate esters are referred to as urethanes, and polymers that include repeating units of carbamate are referred to as POLYURETHANES. Note however that polyurethanes are derived from the polymerization of ISOCYANATES and the singular term URETHANE refers to the ethyl ester of carbamic acid.
Glutathione Transferase
Alkyl and Aryl Transferases
Phosphotransferases (Carboxyl Group Acceptor)
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Transferases (Other Substituted Phosphate Groups)
Carbon-Nitrogen Ligases
Amino Acid Sequence
Ammonia
DNA Nucleotidylexotransferase
Escherichia coli
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.
Azauridine
Coenzyme A-Transferases
Ligases
Dogfish
Binding Sites
Substrate Specificity
Phosphonoacetic Acid
Glutamine
Dihydroorotase
Uridine Monophosphate
Aspartic Acid
Urea
Nucleic Acids
RNA Nucleotidyltransferases
Gene Library
Harmine
Alkaloid isolated from seeds of Peganum harmala L., Zygophyllaceae. It is identical to banisterine, or telepathine, from Banisteria caapi and is one of the active ingredients of hallucinogenic drinks made in the western Amazon region from related plants. It has no therapeutic use, but (as banisterine) was hailed as a cure for postencephalitic Parkinson disease in the 1920's.
Oligonucleotides
Ballistocardiography
Technique of graphic representation of the movements of the body imparted by the ballistic forces (recoil and impact) associated with cardiac contraction and ejection of blood and with the deceleration of blood flow through the large blood vessels. These movements, quantitatively very minute, are translated by a pickup device (transducer) into an electrical potential which is suitably amplified and recorded on a conventional electrocardiograph or other recording machine.
Linear Energy Transfer
Whipple Disease
A chronic systemic infection by a gram-positive bacterium, Tropheryma whippelii, mainly affecting the SMALL INTESTINE but also the JOINTS; CARDIOVASCULAR SYSTEM; and the CENTRAL NERVOUS SYSTEM. The disease is characterized by fat deposits in the INTESTINAL MUCOSA and LYMPH NODES, malabsorption, DIARRHEA with fatty stools, MALNUTRITION, and ARTHRITIS.
Actinobacteria
Central Nervous System Bacterial Infections
Actinomycetales
Legionnaires' Disease
Clostridium thermocellum
Renewable Energy
Biofuels
Clostridium
Cellulase
Gram-Positive Asporogenous Rods, Irregular
Light-dependent changes in redox status of the plastidic acetyl-CoA carboxylase and its regulatory component. (1/77)
Plastidic acetyl-CoA carboxylase (ACCase; EC 6.4.1.2), which catalyses the synthesis of malonyl-CoA and is the regulatory enzyme of fatty acid synthesis, is activated by light, presumably under redox regulation. To obtain evidence of redox regulation in vivo, the activity of ACCase was examined in pea chloroplasts isolated from plants kept in darkness (dark-ACCase) or after exposure to light for 1 h (light-ACCase) in the presence or absence of a thiol-reducing agent, dithiothreitol (DTT). The protein level was similar for light-ACCase and dark-ACCase, but the activity of light-ACCase in the absence of DTT was approx. 3-fold that of dark-ACCase. The light-ACCase and dark-ACCase were activated approx. 2-fold and 6-fold by DTT respectively, indicating that light-ACCase was in a much more reduced, active form than the dark-ACCase. This is the first demonstration of the light-dependent reduction of ACCase in vivo. Measurement of the activities of ACCase, carboxyltransferase and biotin carboxylase in the presence and absence of DTT, and the thiol-oxidizing agent, 5, 5'-dithiobis-(2-nitrobenzoic) acid, revealed that the carboxyltransferase reaction, but not the biotin carboxylase reaction, was redox-regulated. The cysteine residue(s) responsible for redox regulation probably reside on the carboxyltransferase component. Measurement of the pH dependence of biotin carboxylase and carboxyltransferase activities in the ACCase suggested that both components affect the activity of ACCase in vivo at a physiological pH range. These results suggest that the activation of ACCase by light is caused partly by the pH-dependent activation of two components and by the reductive activation of carboxyltransferase. (+info)The biotin domain peptide from the biotin carboxyl carrier protein of Escherichia coli acetyl-CoA carboxylase causes a marked increase in the catalytic efficiency of biotin carboxylase and carboxyltransferase relative to free biotin. (2/77)
Acetyl-CoA carboxylase catalyzes the first committed step in the biosynthesis of long-chain fatty acids. The Escherichia coli form of the enzyme consists of a biotin carboxylase activity, a biotin carboxyl carrier protein, and a carboxyltransferase activity. The C-terminal 87 amino acids of the biotin carboxyl carrier protein (BCCP87) form a domain that can be independently expressed, biotinylated, and purified (Chapman-Smith, A., Turner, D. L., Cronan, J. E., Morris, T. W., and Wallace, J. C. (1994) Biochem. J. 302, 881-887). The ability of the biotinylated form of this 87-residue protein (holoBCCP87) to act as a substrate for biotin carboxylase and carboxyltransferase was assessed and compared with the results with free biotin. In the case of biotin carboxylase holoBCCP87 was an excellent substrate with a K(m) of 0.16 +/- 0.05 mM and V(max) of 1000.8 +/- 182.0 min(-1). The V/K or catalytic efficiency of biotin carboxylase with holoBCCP87 as substrate was 8000-fold greater than with biotin as substrate. Stimulation of the ATP synthesis reaction of biotin carboxylase where carbamyl phosphate reacted with ADP by holoBCCP87 was 5-fold greater than with an equivalent amount of biotin. The interaction of holoBCCP87 with carboxyltransferase was characterized in the reverse direction where malonyl-CoA reacted with holoBCCP87 to form acetyl-CoA and carboxyholoBCCP87. The K(m) for holoBCCP87 was 0.45 +/- 0.07 mM while the V(max) was 2031.8 +/- 231.0 min(-1). The V/K or catalytic efficiency of carboxyltransferase with holoBCCP87 as substrate is 2000-fold greater than with biotin as substrate. (+info)Herbicide sensitivity determinant of wheat plastid acetyl-CoA carboxylase is located in a 400-amino acid fragment of the carboxyltransferase domain. (3/77)
A series of chimeral genes, consisting of the yeast GAL10 promoter, yeast ACC1 leader, wheat acetyl-CoA carboxylase (ACCase; EC 6.4.1.2) cDNA, and yeast ACC1 3'-tail, was used to complement a yeast ACC1 mutation. These genes encode a full-length plastid enzyme, with and without the putative chloroplast transit peptide, as well as five chimeric cytosolic/plastid proteins. Four of the genes, all containing at least half of the wheat cytosolic ACCase coding region at the 5'-end, complement the yeast mutation. Aryloxyphenoxypropionate and cyclohexanedione herbicides, at concentrations below 10 microM, inhibit the growth of haploid yeast strains that express two of the chimeric ACCases. This inhibition resembles the inhibition of wheat plastid ACCase observed in vitro and in vivo. The differential response to herbicides localizes the sensitivity determinant to the third quarter of the multidomain plastid ACCase. Sequence comparisons of different multidomain and multisubunit ACCases suggest that this region includes part of the carboxyltransferase domain, and therefore that the carboxyltransferase activity of ACCase (second half-reaction) is the target of the inhibitors. The highly sensitive yeast gene-replacement strains described here provide a convenient system to study herbicide interaction with the enzyme and a powerful screening system for new inhibitors. (+info)Genetic and biochemical characterization of the alpha and beta components of a propionyl-CoA carboxylase complex of Streptomyces coelicolor A3(2). (4/77)
Two genes, accA1 and accA2, with nearly identical nucleotide sequences were cloned from Streptomyces coelicolor A3(2). The deduced amino acid sequences of the product of these two genes showed high similarity to BcpA2 of Saccharopolyspora erythraea and other biotin-containing proteins from different organisms assumed to be the alpha subunit of a propionyl-CoA carboxylase. A gene, pccB, encoding the carboxyl transferase subunit of this enzyme complex was also characterized. Strains disrupted in accA1 did not show any change in acetyl- or propionyl-CoA carboxylase activity, whilst cell-free extracts of a pccB mutant strain contained a reduced level of propionyl-CoA carboxylase. No mutants in accA2 could be isolated, suggesting that the gene may be essential. Heterologous expression of accA1, accA2 and pccB in Escherichia col and in vitro reconstitution of enzyme activity confirmed that PccB is the beta subunit of a propionyl-CoA carboxylase and that either AccA1 or AccA2 could act as the alpha component of this enzyme complex. The fact that accA2 mutants appear to be inviable suggests that this gene encodes a biotinylated protein that might be shared with other carboxyl transferases essential for the growth of S. coelicolor. (+info)Metabolic biotinylation of recombinant proteins in mammalian cells and in mice. (5/77)
The avidin-biotin system is a fundamental technology in biomedicine for immunolocalization, imaging, nucleic acid blotting, and protein labeling. While this technology is robust, it is limited by the fact that mammalian proteins must be expressed and purified prior to chemical biotinylation using cross-linking agents which modify proteins at random locations to heterogeneous levels and can inactivate protein function. To circumvent this limitation, we demonstrate the ability to metabolically biotinylate tagged proteins in mammalian cells and in mice using the endogenous biotinylation enzymes of the host. Endogenously biotinylated proteins were readily purified from mammalian cells using monomeric avidin and eluted under nondenaturing conditions using only biotin as the releasing agent. This technology should allow recombinant proteins and fragile protein complexes to be produced and purified from mammalian cells as well as from transgenic plants and animals. In addition, this technology may be particularly useful for cell-targeting applications in which proteins or viral gene therapy vectors can be biotinylated at genetically defined sites for combination with other targeting moieties complexed with avidin. (+info)Molecular cloning and characterization of two genes for the biotin carboxylase and carboxyltransferase subunits of acetyl coenzyme A carboxylase in Myxococcus xanthus. (6/77)
We have cloned a DNA fragment from a genomic library of Myxococcus xanthus using an oligonucleotide probe representing conserved regions of biotin carboxylase subunits of acetyl coenzyme A (acetyl-CoA) carboxylases. The fragment contained two open reading frames (ORF1 and ORF2), designated the accB and accA genes, capable of encoding a 538-amino-acid protein of 58.1 kDa and a 573-amino-acid protein of 61.5 kDa, respectively. The protein (AccA) encoded by the accA gene was strikingly similar to biotin carboxylase subunits of acetyl-CoA and propionyl-CoA carboxylases and of pyruvate carboxylase. The putative motifs for ATP binding, CO(2) fixation, and biotin binding were found in AccA. The accB gene was located upstream of the accA gene, and they formed a two-gene operon. The protein (AccB) encoded by the accB gene showed high degrees of sequence similarity with carboxyltransferase subunits of acetyl-CoA and propionyl-CoA carboxylases and of methylmalonyl-CoA decarboxylase. Carboxybiotin-binding and acyl-CoA-binding domains, which are conserved in several carboxyltransferase subunits of acyl-CoA carboxylases, were found in AccB. An accA disruption mutant showed a reduced growth rate and reduced acetyl-CoA carboxylase activity compared with the wild-type strain. Western blot analysis indicated that the product of the accA gene was a biotinylated protein that was expressed during the exponential growth phase. Based on these results, we propose that this M. xanthus acetyl-CoA carboxylase consists of two subunits, which are encoded by the accB and accA genes, and occupies a position between prokaryotic and eukaryotic acetyl-CoA carboxylases in terms of evolution. (+info)An isoleucine/leucine residue in the carboxyltransferase domain of acetyl-CoA carboxylase is critical for interaction with aryloxyphenoxypropionate and cyclohexanedione inhibitors. (7/77)
cDNA fragments encoding the carboxyltransferase domain of the multidomain plastid acetyl-CoA carboxylase (ACCase) from herbicide-resistant maize and from herbicide-sensitive and herbicide-resistant Lolium rigidum were cloned and sequenced. A Leu residue was found in ACCases from herbicide-resistant plants at a position occupied by Ile in all ACCases from sensitive grasses studied so far. Leu is present at the equivalent position in herbicide-resistant ACCases from other eukaryotes. Chimeric ACCases containing a 1000-aa fragment of two ACCase isozymes found in a herbicide-resistant maize were expressed in a yeast ACC1 null mutant to test herbicide sensitivity of the enzyme in vivo and in vitro. One of the enzymes was resistant/tolerant, and one was sensitive to haloxyfop and sethoxydim, rendering the gene-replacement yeast strains resistant and sensitive to these compounds, respectively. The sensitive enzyme has an Ile residue, and the resistant one has a Leu residue at the putative herbicide-binding site. Additionally, a single Ile to Leu replacement at an equivalent position changes the wheat plastid ACCase from sensitive to resistant. The effect of the opposite substitution, Leu to Ile, makes Toxoplasma gondii apicoplast ACCase resistant to haloxyfop and clodinafop. In this case, inhibition of the carboxyltransferase activity of ACCase (second half-reaction) of a large fragment of the Toxoplasma enzyme expressed in Escherichia coli was tested. The critical amino acid residue is located close to a highly conserved motif of the carboxyltransferase domain, which is probably a part of the enzyme active site, providing the basis for the activity of fop and dim herbicides. (+info)Motility of single one-headed kinesin molecules along microtubules. (8/77)
The motility of single one-headed kinesin molecules (K351 and K340), which were truncated fragments of Drosophila two-headed kinesin, has been tested using total internal reflection fluorescence microscopy. One-headed kinesin fragments moved continuously along the microtubules. The maximum distance traveled until the fragments dissociated from the microtubules for both K351 and K340 was approximately 600 nm. This value is considerably larger than the space resolution of the measurement system (SD approximately 30 nm). Although the movements of the fragments fluctuated in forward and backward directions, statistical analysis showed that the average movements for both K340 and K351 were toward the plus end of the microtubules, i.e., forward direction. When BDTC (a 1.3-S subunit of Propionibacterium shermanii transcarboxylase, which binds weakly to a microtubule), was fused to the tail (C-terminus) of K351, its movement was enhanced, smooth, and unidirectional, similar to that of the two-headed kinesin fragment, K411. However, the travel distance and velocity of K351BDTC molecules were approximately 3-fold smaller than that of K411. These observations suggest that a single kinesin head has basal motility, but coordination between the two heads is necessary for stabilizing the basal motility for the normal level of kinesin processivity. (+info)
Inhibition and nucleic acid binding studies of the carboxyltransferase by Brian Benson
Ban novn k Velutina (rostlina: Musa velutina) - 5 semen ban novn ku - Eshop -> www.rostliny...
Novan (NOVN) Sets New 52-Week Low at $3.40 - Watch List News
How to Form a Corporation in Florida | Nolo
Nursing Home Abuse | Nolo.com
What is a quit claim deed form? | Reference.com
Citrónovník pravý - Wikipédia
Transthyretin suppresses the toxicity of oligomers formed by misfolded proteins in vitro | IRIS Università degli Studi di...
accA - Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha - Helicobacter pylori FD506 - accA gene & protein
I Corinthios 10 VULGATE - nolo enim vos ignorare fratres quoniam - Bible Gateway
3765. Misbranding of dextro-amphetamine sulfate tablets. U. S v. Frank A. Ponzo (Ponzos Drug Store). Plea of nolo contendere....
accD3 - Putative acetyl-coenzyme A carboxylase carboxyl transferase subunit beta - Mycobacterium tuberculosis (strain ATCC...
Novartis (NOVN) Given a CHF 90 Price Target at Deutsche Bank - StockNewsTimes
NOLO Brings VR Motion Tracking To Smartphones - Science & Technology World Website
200ug-Anti-Ornithine Carbamoyl Transferase (OCT)-polyclonal Antibody | Technique alternative | 01015884261 - Amoy Tope
3001. Misbranding of amphetamine hydrochloride tablets. U. S. v. Charles R. Wirth (Wirth Drug Store). Plea of nolo contendere....
Novartis (NOVN) Given a CHF 92 Price Target by Morgan Stanley Analysts - Community Financial News
Ask the Contractor: All about grasshoppers | The Daily Courier | Prescott, AZ
RCSB PDB
for 1A6X
Metabolic engineering of microorganisms for the production of L-arginine and its derivatives | Microbial Cell Factories | Full...
Mechanistic studies of agmatine deiminase from multiple bacterial spec by Justin E. Jones, Christina J. Dreyton et al.
Sipsey Street Irregulars: Sipsey Street Exclusive: Mike Vanderboegh and David Codrea file ethics complaint on Eric Holder with...
Biotin Carboxyl Carrier Protein - Rediff Pages
Complex formation and regulation of Escherichia coli acetyl-CoA carbox by Tyler Craig Broussard
Molecules | Free Full-Text | Computational Redesign of Bacterial Biotin Carboxylase Inhibitors Using Structure-Based Virtual...
Kinetic and spectroscopic studies on a superoxide dismutase from Propionibacterium shermanii that is active with iron or...
Biotin carboxylase | Article about biotin carboxylase by The Free Dictionary
EC 4.1.1.41
3,5-Difluoro acetophenone 123577-99-1, China 3,5-Difluoro acetophenone 123577-99-1 Manufacturers, China 3,5-Difluoro...
KEGG BRITE: KEGG Modules
Propionyl-CoA carboxylase regulator elisa and antibody
MYLK - Role for Caspase-Mediated Cleavage of Rad51 in Induction of Apoptosis
Genetic Mutations & Gene Therapy
Acetophenone Manufacturers | Suppliers | Exporters in India
NASPA Word of the Day
RCSB PDB - 3GLK: The biotin carboxylase (BC) domain of human Acetyl-CoA Carboxylase 2 (ACC2)
EMBL: CP001022.PE450
Popular Weight Loss Myths: Dont Believe the Hype | HubPages
SOMEONE TELL ME IS THIS WORTH THE HYPE? I SEE … | Q&A for Summer Fridays Cloud Dew Oil-Free Gel Cream 1.70 oz/ 50 mL
Noirdrakkar Tries Aventus: Is Aventus Worth The Hype? - Page 2
Hype & Hope - News
Hype Williams - Rainbow Edition - Boomkat
Acca Kappa Beechwood Comb With Handle - StyleInvyte
SOA? That was just a fad. Cloud Computing? Now that is the real deal. So says Springs Rod Johnson
Acetophenone
Organization and Expression of a Thermus thermophilusArginine Cluster: Presence of Unidentified Open Reading Frames and Absence...
fur protein (Ewingella americana) - STRING interaction network
nikR protein (Klebsiella pneumoniae) - STRING interaction network
Contribution of glibenclamide-sensitive, ATP-dependent K+ channel activation to acetophenone analogues-mediated in vitro...
4-(IMIDAZOL-1-YL)ACETOPHENONE 10041-06-2 H-NMR | C-NMR Spectral Analysis NMR Spectrum
TIGR01195
Acetophenone Manufacturers, Suppliers, Exporters in Aurangabad, India
SWISS-MODEL Repository | A1VYG1
The Interaction between Amyloid Prefibrillar Oligomers of Salmon Calcitonin and a Lipid-Raft Model: Molecular Mechanisms...
32 CFR § 199.2 - Definitions. | CFR | US Law | LII / Legal Information Institute
Free Case Evaluation | LawFirms.com
Radiograpy Requirements Information | Richland Community College
Ornithine Carbamoyltransferase Antibody (NBP1-88121): Novus Biologicals
Omega Fatty Acids - a Hype or Help?
Omega Fatty Acids - a Hype or Help?
Editorials: Screening for Ovarian Cancer-More Hype Than Hope? - American Family Physician
Hype Barbell set - Gym equipment from monster supplements.com | Monster Supplements
Shaken by hype, self-driving leaders adopt new strategy: Shutting up - The Washington Post
Hype Cycle for Digital Marketing, 2013
DevOps Demystified: Finding Value in the Hype - Steven Murawski Tickets, Wed, Dec 11, 2013 at 5:30 PM | Eventbrite
A question of ethics | Student Accountant magazine archive | Publications | Students | ACCA | ACCA Global
Hyped Nature paper & author knighthood 2 days later raise red flags - The Niche
Polk 00240 : CDS information --- DoBISCUIT
Wheelchair Kamikaze: Hype or Hope? Much Touted Oral MS Drug Tecfidera (BG 12) Approved byFDA.
Wheelchair Kamikaze: Hype or Hope? Much Touted Oral MS Drug Tecfidera (BG 12) Approved byFDA.
Skincare Products: Hype vs. Reality
Dont believe hydrogen and nuclear hype - they cant get us to net zero carbon by 2050 | Energy | The Guardian
The hydrogen economy: Hope or hype? |
CompositesWorld
Cancer and meat - too much hype?
Clean Label Foods: Healthy or Just Hype? |...
Aluminum hype | MacRumors Forums
The hype about 5G | Part 2 | Islands Sounder
Help or Hype? Treat Your Cold Naturally
The Hoxton Hotel Amsterdam. Believe The Hype! - Fabelish
Krokodil Hype: Is Toxic Flesh-Eating Street Drug In Canada?
Halki Diabetes Remedy Reviews | Examining the Hype 2020 - Health & Fitness Vigilante
Len Saltz on Hype vs Hope, Drug Costs, and ASCO 2017
Zz Snore Reviews - Is It Legit or Just Hype?
Hulu Upfront Hypes Handmaids Tale Success, Shifts Away From Subscriber Numbers
List of MeSH codes (D08)
... carboxyl and carbamoyl transferases MeSH D08.811.913.555.275.200 - aspartate carbamoyltransferase MeSH D08.811.913.555.275.600 ... glutathione transferase MeSH D08.811.913.225.500.500 - glutathione S-transferase pi MeSH D08.811.913.225.575 - ... carbamoyl-phosphate synthase (ammonia) MeSH D08.811.464.259.400 - carbon-nitrogen ligases with glutamine as amide-n-donor MeSH ... adp ribose transferases MeSH D08.811.913.400.725.115.180 - cholera toxin MeSH D08.811.913.400.725.115.220 - diphtheria toxin ...
Ribonucleotide
Orotate is covalently linked with phosphoribosyl pyrophosphate (PRPP) by orotate phosphoribysol-transferase yielding orotidine ... A carboxyl group is attached to AIR by N5-CAIR synthetase to form N5-Carboxyaminoimidazole ribonucleotide (N5-CAIR), which is ... ring begins with the conversion of Aspartate to N-Carbamoylaspartate by undergoing a condensation reaction with carbamoyl ...
Nucleotide
... aspartate carbamoyltransferase catalyzes a condensation reaction between aspartate and carbamoyl phosphate to form carbamoyl ... Next, a glycine is incorporated fueled by ATP hydrolysis, and the carboxyl group forms an amine bond to the NH2 previously ... Orotate phosphoribosyltransferase (PRPP transferase) catalyzes the net reaction yielding orotidine monophosphate (OMP): Orotate ... The synthesis of the pyrimidines CTP and UTP occurs in the cytoplasm and starts with the formation of carbamoyl phosphate from ...
Aminoacyl tRNA synthetase
The amino acids are attached to the hydroxyl (-OH) group of the adenosine via the carboxyl (-COOH) group. ... EC2 Transferases (list). *EC3 Hydrolases (list). *EC4 Lyases (list). *EC5 Isomerases (list) ...
Carboxyl and Carbamoyl Transferases | Profiles RNS
"Carboxyl and Carbamoyl Transferases" by people in this website by year, and whether "Carboxyl and Carbamoyl Transferases" was a ... "Carboxyl and Carbamoyl Transferases" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, ... Below are the most recent publications written about "Carboxyl and Carbamoyl Transferases" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Carboxyl and Carbamoyl Transferases". ...
Transcarboxylase: one of nature's early nanomachines.
Transferases | definition of transferases by Medical dictionary
... transferases explanation free. What is transferases? Meaning of transferases medical term. What does transferases mean? ... Looking for online definition of transferases in the Medical Dictionary? ... carboxyl- and carbamoyltransferases, 2.1.3; and amidinotransferases, 2.1.4); acyl residues (acyltransferases, 2.3); glycosyl ... transferases. Also found in: Dictionary, Thesaurus, Encyclopedia.. Related to transferases: Lyases, Ligases, Hydrolases, ...
List of MeSH codes (D08) - Wikipedia
... carboxyl and carbamoyl transferases MeSH D08.811.913.555.275.200 - aspartate carbamoyltransferase MeSH D08.811.913.555.275.600 ... glutathione transferase MeSH D08.811.913.225.500.500 - glutathione S-transferase pi MeSH D08.811.913.225.575 - ... carbamoyl-phosphate synthase (ammonia) MeSH D08.811.464.259.400 - carbon-nitrogen ligases with glutamine as amide-n-donor MeSH ... adp ribose transferases MeSH D08.811.913.400.725.115.180 - cholera toxin MeSH D08.811.913.400.725.115.220 - diphtheria toxin ...
Health Sciences Research - Research Output
- Mayo Clinic
CA2426774A1 - Method for generating a library of oligonucleotides comprising a controlled distribution of mutations
-...
102000007132 Carboxyl and Carbamoyl Transferases Human genes 0 description 1 * 108010072957 Carboxyl and Carbamoyl Transferases ... 108010031311 Intramolecular Transferases Proteins 0 description 1 * 102000005385 Intramolecular Transferases Human genes 0 ... 108010077385 Coenzyme A-Transferases Proteins 0 description 1 * 102000010079 Coenzyme A-Transferases Human genes 0 description ...
Category:EC 2.1.3
Activation and Inhibition of Pyruvate Carboxylase from Rhizobium etli<...
... domain with pyruvate carboxylation in the carboxyl transferase (CT) domain. Initial velocity plots of free Mg2+ vs pyruvate ... while phosphonoacetate inhibited both the phosphorylation of MgADP by carbamoyl phosphate (K-i = 0.026 mM) and pyruvate ... domain with pyruvate carboxylation in the carboxyl transferase (CT) domain. Initial velocity plots of free Mg2+ vs pyruvate ... domain with pyruvate carboxylation in the carboxyl transferase (CT) domain. Initial velocity plots of free Mg2+ vs pyruvate ...
US Patent # 4,299,916. Preferential signal production on a surface in immunoassays - Patents.com
... and related transferases 2.1.3 Carboxyl- and carbamoyltransferases 2.1.4 Amidinotransferases 2.2 Transferring aldehydic or ... aldolyase 4.2.1 Hydro-lyases 1. carbonic anhydrase 5. Isomerase 5.4 Intramolecular transferases 5.4.2 Transferring phosphoryl ... Transferases, Class 4 Lyases and Class 5, Isomerases, can also be of interest in particular situations. The following table has ... Transferases 2.7 Transferring phosphorus-containing groups 2.7.1 Phosphotransferases with CH--OH as acceptor 1. hexokinase 2. ...
DeCS
Transferase, Carbamoyl. Transferase, Carboxyl. Transferases, Carbamoyl. Transferases, Carboxyl. Tree number(s):. D08.811. ... Carbamoyl Transferase Carbamoyl Transferases Carbamoyltransferase Transferase, Carbamoyl Transferases, Carbamoyl ... Carbamoyl Transferases. Carbamoyltransferase. Carbamoyltransferases. Carboxyl Transferase. Carboxyl Transferases. Carboxyl and ... Carboxyl and carbamoyl transferases Entry term(s):. Carbamoyl Transferase. ...
Find Research outputs
- the UWA Profiles and Research Repository
Toxicity of protein oligomers is rationalized by a function combining size and surface hydrophobicity. - PubMed - NCBI
DeCS Ingl s+escopo
Carboxyl and Carbamoyl Transferases .. Carbamoyl Transferases .. Carbamoyltransferases .. Carboxyl Transferases .. ... Transferases, Carbamoyl .. Transferases, Carboxyl .. A group of enzymes that catalyze the transfer of carboxyl- or carbamoyl- ... One-Carbon Group Transferases .. One Carbon Group Transferases .. Single Carbon Group Transferases .. Transferases, One-Carbon ... D08.811.913 Transferases .. D08.811.913.555 One-Carbon Group Transferases .. D08.811.913.555.275 Carboxyl and Carbamoyl ...
Search | Global Index Medicus
Carbamoyl phosphate synthetase, small subunit N-terminal domain superfamily
The SCOP classification for the Carbamoyl phosphate synthetase, small subunit N-terminal domain superfamily including the ... Transferases. 1. 0. --. INHERITED FROM: Carboxyl- and carbamoyltransferases ,, Aspartate carbamoyltransferase. Enzyme ... Carboxyl- and carbamoyltransferases. 0.000002517. Highly Informative. Direct. Document: EC annotation of SCOP domains. Enzyme ... Transferases. 1. 0.301. --. INHERITED FROM: Aspartate carbamoyltransferase ,, Carboxy- and carbamoyltransferases. Enzyme ...
Carbamoyl phosphate synthetase, large subunit connection domain superfamily
The SCOP classification for the Carbamoyl phosphate synthetase, large subunit connection domain superfamily including the ... Transferases. 1. 0. --. INHERITED FROM: Carboxyl- and carbamoyltransferases ,, Aspartate carbamoyltransferase. Enzyme ... Carboxyl- and carbamoyltransferases. 0.00001407. Highly Informative. Direct. Document: EC annotation of SCOP domains. Enzyme ... Transferases. 1. 0.302. --. INHERITED FROM: Carboxy- and carbamoyltransferases ,, Aspartate carbamoyltransferase. Enzyme ...
ABP73856.1 protein (Shewanella putrefaciens) - STRING interaction network
... carboxyl transferase subunit alpha/carboxyl transferase subunit beta/biotin carboxylase. PFAM- phospholipid/glycerol ... PFAM- biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl- ... carboxyl transferase subunit alpha/carboxyl transferase subunit beta/biotin carboxylase (1517 aa) ... carboxyl transferase subunit alpha/carboxyl transferase subunit beta/biotin carboxylase ...
Noca 4502 protein (Nocardioides sp. JS614) - STRING interaction network
Ribonucleotide - Wikipedia
Orotate is covalently linked with phosphoribosyl pyrophosphate (PRPP) by orotate phosphoribysol-transferase yielding orotidine ... A carboxyl group is attached to AIR by N5-CAIR synthetase to form N5-Carboxyaminoimidazole ribonucleotide (N5-CAIR), which is ... ring begins with the conversion of Aspartate to N-Carbamoylaspartate by undergoing a condensation reaction with carbamoyl ...
EMBL: BX251410
"Carboxyl transferase domain Score = 893.4 E-value = FT 4.8e-266" FT CDS_pept 25738..26484 FT /transl_table=11 FT /locus_tag=" ... "PS00867 Carbamoyl-phosphate synthase subdomain FT signature 2." FT misc_feature complement(21874..22210) FT /note="Carbamoyl- ... carboxyl terminus Score = FT 135.1 E-value = 8.7e-38" FT CDS_pept 6438..8897 FT /transl_table=11 FT /gene="gyrA1" FT /locus_tag ... "Formyl transferase Score = 147.5 E-value = 1.7e-41" FT CDS_pept 93477..95105 FT /transl_table=11 FT /gene="purH" FT /locus_tag ...
Genome-scale metabolic analysis of Clostridium thermocellum for bioethanol production | BMC Systems Biology | Full Text
As a specific example of this process, consider the reaction corresponding to carbamoyl-phosphate synthase (R_CBPS), EC 6.3. ... carboxyl transferase. A0RY61. 8.00E-169. 6.3.4.14. biotin carboxylase. Cthe_0949 ... We found two C. thermocellum genes annotated as "carbamoyl-phosphate synthase, small subunit" (Cthe_1867, Cthe_0950) and two ... a small glutamine-hydrolyzing chain and a large chain that synthesizes carbamoyl phosphate. ...
dog friendly places in dubai 2020
Carbamoyl phosphate combines with aspartate to form carbamoyl aspartate aided by the enzyme aspartate transcarbamoylase. ... It is then convâ ¦ The latter forms an amide with 4-carboxyl group in presence of synthetase, and a succinocarboxamide is ... This is a genetic disorder caused due to the deficiency of the enzyme Hypoxanthine Guanine Phospho Ribosyl Transferase (HGPRT ... in this pathway is the synthesis of carbamoyl phosphate from CO2 and NH4+ by carbamoyl phosphate from CO2 and NH4+ by carbamoyl ...
Amidinotransferases | REACH
KEGG BRITE: Enzymes - Aeromonas hydrophila pc104A
Search Articles | University of Toronto Libraries
Methylglyoxal synthase-like superfamily
Carboxyl- and carbamoyltransferases. 1. Highly Informative. Inherited. Enzyme Commission (EC). In cyclic amides. 1. Highly ... Hydroxymethyl-, formyl- and related transferases. 0. 1.356. Informative. DIRECT. Enzyme Commission (EC). Carbamoyl-phosphate ... Carbamoyl-phosphate synthase (ammonia). 0.0000000000225. 2.233. Highly Informative. DIRECT. Enzyme Commission (EC). Carboxyl- ... Hydroxymethyl-, formyl- and related transferases. 0. Informative. Direct. Enzyme Commission (EC). Carbamoyl-phosphate synthase ...
METHODS AND COMPOSITIONS FOR ISOLATING, IDENTIFYING AND CHARACTERIZING MONOCOT PLASTIDIC ACCASE HERBICIDE TOLERANT...
0157] Region 8: pfam01039 (Carboxyl_trans) Carboxyl transferase domain (of biotin-dependent carboxylases). [0158] The carboxyl ... 0151] Region 3: pfam02786 (CPSase_L_D2) Carbamoyl-phosphate synthase L chain, ATP binding domain; [0152] Region 4: pfam02785 ( ... 0128] As used herein, and "herbicide sensitivity region" (HSR) is an amino acid sequence present in the carboxyl transferase ... 0159] Region 8 comprises the carboxyl transferase domain of the ACCase enzyme of the invention. Herbicide sensitivity has been ...
"Activation and Inhibition of Pyruvate Carboxylase from Rhizobium etli" by Tonya N. Zeczycki, Ann L. Menefee et al.
... while phosphonoacetate inhibited both the phosphorylation of MgADP by carbamoyl phosphate (Ki = 0.026 mM) and pyruvate ... domain with pyruvate carboxylation in the carboxyl transferase (CT) domain. Initial velocity plots of free Mg2+ vs pyruvate ... domain with pyruvate carboxylation in the carboxyl transferase (CT) domain. Initial velocity plots of free Mg2+ vs pyruvate ... while phosphonoacetate inhibited both the phosphorylation of MgADP by carbamoyl phosphate (Ki = 0.026 mM) and pyruvate ...
The use of proteomic techniques to study the physiology and virulence of staphylococcus aureus
... carboxyl transferase, beta subunit (accD) SACOL1748 3 sdrC protein (sdrC) SACOL0608 2 Staphylococcus aureus sex pheromone (camS ... PUR9 18 6 Carbamoyl phosphate synthase large chain Q5HGM9,CARB 12 12 Probable thiol peroxidase Q5HF61,TPX 14 7 Chaperone ... DEF 0 2 Acetyl coenzyme A carboxylase carboxyl transferase subunit alpha Q5HF74,ACCA 3 0 UDP N acetylmuramoylalanine -D ... PTPA 5 2 Acetyl coenzyme A carboxylase carboxyl transferase subunit beta Q5HF73,ACCD 4 4 GTP sensing transcriptional ...
Biotin carboxylase3
- The current steady-state kinetic investigation indicates that both acetyl-CoA and Mg2+ assist in coupling the MgATP-dependent carboxylation of biotin in the biotin carboxylase (BC) domain with pyruvate carboxylation in the carboxyl transferase (CT) domain. (edu.au)
- The current steady-state kinetic investigation indicates that both acetyl-CoA and Mg 2+ assist in coupling the MgATP-dependent carboxylation of biotin in the biotin carboxylase (BC) domain with pyruvate carboxylation in the carboxyl transferase (CT) domain. (marquette.edu)
- In Escherichia coli, ACC is comprised of three functional modules: the biotin carboxylase (BC), the biotin carboxyl carrier protein (BCCP) and the carboxyl transferase (CT). (embl-heidelberg.de)
Phosphate6
- Acetyl phosphate was determined to be a suitable phosphoryl donor for the catalytic phosphorylation of MgADP, while phosphonoacetate inhibited both the phosphorylation of MgADP by carbamoyl phosphate (K-i = 0.026 mM) and pyruvate carboxylation (K-i = 2.5 mM). (edu.au)
- An enzyme that catalyzes the conversion of carbamoyl phosphate and L-aspartate to yield orthophosphate and N-carbamoyl-L-aspartate. (bireme.br)
- Pyrimidines are synthesized first from aspartate and carbamoyl-phosphate in the cytoplasm to the common precursor ring structure orotic acid, onto which a phosphorylated ribosyl unit is covalently linked. (meddic.jp)
- The synthesis of the pyrimidines CTP and UTP occurs in the cytoplasm and starts with the formation of carbamoyl phosphate from glutamine and CO 2 . (meddic.jp)
- Next, aspartate undergoes a condensation reaction with carbamoyl-phosphate to form orotic acid. (meddic.jp)
- carbamoyl-phosphate synthetase 2, asp. (broadinstitute.org)
Synthetase1
- It is then convâ ¦ The latter forms an amide with 4-carboxyl group in presence of synthetase, and a succinocarboxamide is formed. (abskuwait.com)
Enzymes2
- A group of enzymes that catalyze the transfer of carboxyl- or carbamoyl- groups. (uchicago.edu)
- Enzymes of a subclass of TRANSFERASES that catalyze the transfer of an amidino group from donor to acceptor. (sickkids.ca)
Ornithine1
- Arginine deiminase, ornithine carbamoyl transferase, and enolase have been identified from secreted proteins of Giardia intestinalis as immunodominant antigens [ 9 ]. (parasitol.kr)
Enzyme2
- In a subsequent cyclization reaction, the enzyme Aspartate carbamoyltransferase forms N-carbamoyl-aspartate which is converted into dihydroorotic acid by dihydroorotase. (meddic.jp)
- The enzyme takes the end methyl residue from the methionine side chain and adds it to the side chain carboxyl group of L-isoaspartate or D-aspartate to create a methyl ester. (xfam.org)
Aspartate1
- Fluoride induced increase in the activities of Alanine and Aspartate transferases were reported (Miszta and Dabrowski, 1986), in Wistan rats. (thefreedictionary.com)
Catalysis1
- During catalysis, carboxybiotin is translocated to the carboxyltransferase domain where the carboxyl group is transferred to the acceptor substrate, pyruvate. (embl-heidelberg.de)
Hydroxyl3
- Q: Where do the carboxyl and hydroxyl groups point in bile salts? (caribbeanmedstudent.com)
- Q: How many carboxyl and how many hydroxyl groups are in a bile salt? (caribbeanmedstudent.com)
- The amino acids are attached to the hydroxyl (-OH) group of the adenosine via the carboxyl (-COOH) group. (wikipedia.org)
Subclass1
- A subclass of transferases that transfer chemical groups containing a single carbon. (bireme.br)
Comt1
- 11. The method according to claim 10, wherein said at least one other pharmaceutically active ingredient is chosen from the group consisting of: levodopa, carbidopa-levodopa, dopamine agonists, monoamine oxidase B (MAO-B) inhibitors, catechol-O-methyl transferase (COMT) inhibitors, NMDA receptor antagonists, acetylcholinesterase inhibitors, and mixture thereof. (sumobrain.com)
Cysteine1
- Subsequently, the sequence AAX is proteolytically cleaved, and the newly formed carboxyl-terminal farnesyl cysteine is finally methylated ( Zhang and Casey, 1996 ). (aspetjournals.org)
MeSH1
- Carboxyl and Carbamoyl Transferases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uchicago.edu)
Group2
- Many studies on the carboxyltransferase domain of PC have demonstrated an enhanced oxaloacetate decarboxylation activity in the presence of oxamate and it has been shown that oxamate accepts a carboxyl group from carboxybiotin during oxaloacetate decarboxylation. (embl-heidelberg.de)
- The surface of the micro/nanomaterial comprises a carboxyl group or poten. (sumobrain.com)
Drugs1
- Another approach involves the use of vegetable drugs such as Polygalae root extract, which has been shown to enhance choline-acetylcholine transferase (CAT) activity and nerve growth factor (NGF) secretion in brain. (allindianpatents.com)
Amino Acids1
- PIMT acts to transfer methyl groups from S-adenosyl-L-methionine to the alpha side chain carboxyl groups of damaged L-isoaspartyl and D-aspartyl amino acids. (xfam.org)
Decarboxylation1
- PRPP transferase catalyzes both the ribosylation and decarboxylation reactions, forming UMP from orotic acid in the presence of PRPP. (meddic.jp)
Alpha1
- Microsomal and alpha-class glutathione transferases were also induced transcriptionally. (thefreedictionary.com)
Humans1
- Zeta, a novel class of glutathione transferases in a range of species from plants to humans. (thefreedictionary.com)
Glutamine1
- This compound interacts with water and L-glutamine through a amidophosphoribosyl transferase resulting in a pyrophosphate, L-glutamic acid and a 5-phosphoribosylamine. (kasinokamu.com)
Activity2
- Glutathione s transferase and hydrolytic activity in a tetrachlorvinphos-resistant strain of housefly and their influence on resistance. (thefreedictionary.com)
- Glutathione transferases structure and catalytic activity. (thefreedictionary.com)
Year1
- This graph shows the total number of publications written about "Carboxyl and Carbamoyl Transferases" by people in this website by year, and whether "Carboxyl and Carbamoyl Transferases" was a major or minor topic of these publications. (uchicago.edu)
Structure1
- Liu, Crystallographic and Mechanistic Studies of Class Mu Glutathione S- Transferases , in Proceedings of the International Meeting on Structure and Function of Glutathione Transferases , K. (thefreedictionary.com)