Carbon Monoxide Poisoning
Carbon Monoxide
Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
Oximetry
The determination of oxygen-hemoglobin saturation of blood either by withdrawing a sample and passing it through a classical photoelectric oximeter or by electrodes attached to some translucent part of the body like finger, earlobe, or skin fold. It includes non-invasive oxygen monitoring by pulse oximetry.
Methylene Chloride
Hemoglobins
Smoke Inhalation Injury
Methemoglobinemia
The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed)
Oxyhemoglobins
Blood Gas Monitoring, Transcutaneous
The noninvasive measurement or determination of the partial pressure (tension) of oxygen and/or carbon dioxide locally in the capillaries of a tissue by the application to the skin of a special set of electrodes. These electrodes contain photoelectric sensors capable of picking up the specific wavelengths of radiation emitted by oxygenated versus reduced hemoglobin.
Chromatography, Gas
Fractionation of a vaporized sample as a consequence of partition between a mobile gaseous phase and a stationary phase held in a column. Two types are gas-solid chromatography, where the fixed phase is a solid, and gas-liquid, in which the stationary phase is a nonvolatile liquid supported on an inert solid matrix.
Spectrophotometry
Cotinine
Nicotine
Erythroblastosis, Fetal
A condition characterized by the abnormal presence of ERYTHROBLASTS in the circulation of the FETUS or NEWBORNS. It is a disorder due to BLOOD GROUP INCOMPATIBILITY, such as the maternal alloimmunization by fetal antigen RH FACTORS leading to HEMOLYSIS of ERYTHROCYTES, hemolytic anemia (ANEMIA, HEMOLYTIC), general edema (HYDROPS FETALIS), and SEVERE JAUNDICE IN NEWBORN.
ABO Blood-Group System
The major human blood type system which depends on the presence or absence of two antigens A and B. Type O occurs when neither A nor B is present and AB when both are present. A and B are genetic factors that determine the presence of enzymes for the synthesis of certain glycoproteins mainly in the red cell membrane.
Blood Group Incompatibility
An antigenic mismatch between donor and recipient blood. Antibodies present in the recipient's serum may be directed against antigens in the donor product. Such a mismatch may result in a transfusion reaction in which, for example, donor blood is hemolyzed. (From Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984).
Jaundice
Tars
Seals, Earless
Pinnipedia
Diving
Thoracoplasty
Hydrogen Cyanide
Role of nitric oxide-derived oxidants in vascular injury from carbon monoxide in the rat. (1/461)
Studies were conducted with rats to investigate whether exposure to CO at concentrations frequently found in the environment caused nitric oxide (NO)-mediated vessel wall changes. Exposure to CO at concentrations of 50 parts per million or higher for 1 h increased the concentration of nitrotyrosine in the aorta. Immunologically reactive nitrotyrosine was localized in a discrete fashion along the endothelial lining, and this was inhibited by pretreatment with the NO synthase (NOS) inhibitor Nomega-nitro-L-arginine methyl ester (L-NAME). The CO-induced elevations of aortic nitrotyrosine were not altered by neutropenia or thrombocytopenia, and CO caused no change in the concentration of endothelial NOS. Consequences from NO-derived stress on the vasculature included an enhanced transcapillary efflux of albumin within the first 3 h after CO exposure and leukocyte sequestration that became apparent 18 h after CO exposure. Oxidized plasma low-density lipoprotein was found immediately after CO exposure, but this was not inhibited by L-NAME pretreatment. We conclude that exposure to relatively low CO concentrations can alter vascular status by several mechanisms and that many changes are linked to NO-derived oxidants. (+info)High predictive value of red cell volume measurement using carboxy-haemoglobin in a rabbit model of haemorrhage. (2/461)
We have studied the accuracy of blood volume measurements using carbon monoxide (CO)-labelled haemoglobin (COHb) injection and dilution (CO method) by comparing changes in red cell volume (RCV) measured using the CO method and 51Cr-labelled erythrocyte dilution (51Cr method) in a haemorrhage and infusion model in rabbits. RCV was measured repeatedly using the CO method at four different blood volume stages (stages I-IV). At stages I and IV, RCV was measured simultaneously using the 51Cr method. In comparing the sum of the circulating RCV and extracted RCV (SUM RCV) using the CO method, the values were almost equal and there were no significant differences between the values at the four stages. In comparing circulating RCV measured using the CO method and the 51Cr method, mean difference between the two methods was 0.80 (SD 0.76) ml kg-1 or 4.7 (4.6)%, and a positive correlation was observed (r = 0.91). We conclude that the CO method can be used to measure blood volume during perioperative periods in infants because it avoids use of a radioactive tracer, is simple and repeated measurements are possible. (+info)A physiological model for predicting carboxyhemoglobin formation from exposure to carbon monoxide in rats. (3/461)
A time-dependent simulation model, based on the Coburn-Forster-Kane equation, was written in Advanced Continuous Simulation Language to predict carboxyhemoglobin (HbCO) formation and dissociation in F-344 rats during and after exposure to 500 parts/million CO for 1 h. Blood-gas analysis and CO-oximetry were performed on samples collected during exposure and off-gassing of CO. Volume displacement plethysmography was used to measure minute ventilation (VE) during exposure. CO diffusing capacity in the lung (DLCO) was also measured. Other model parameters measured in the animals included blood pH, total blood volume, and Hb concentration. Comparisons between model predictions using values for VE, DLCO, and the Haldane coefficient cited in the literature and predictions using measured VE, DLCO, and calculated Haldane coefficient for individual animals were made. General model predictions using values for model parameters derived from the literature agreed with published HbCO values by a factor of 0.987 but failed to simulate experimental data. On average, the general model overpredicted measured HbCO level by nearly 9%. A specific model using the means of measured variables predicted HbCO concentration within a factor of 0.993. When experimentally observed parameter fluctuations were included, the specific model predictions reflected experimental effects on HbCO formation. (+info)Neonatal bilirubin production, reflected by carboxyhaemoglobin concentrations, in Down's syndrome. (4/461)
AIM: To determine whether increased bilirubin production, reflected by blood carboxyhaemoglobin (COHb) values, is responsible for hyperbilirubinaemia in cases of Down's syndrome with no obvious cause for excessive jaundice. METHODS: Blood was sampled on the third day of life for COHb, total haemoglobin (tHb), and serum total bilirubin, from 19 consecutively born neonates with Down's syndrome (a subset of 34 term babies), who had developed hyperbilirubinaemia (serum bilirubin >/= 256 micromol), and from 32 term controls. COHb, measured by gas chromatography, was corrected for inspired CO (COHbc) and expressed as a percentage of tHb. RESULTS: Significantly more of the Down's syndrome subset developed hyperbilirubinaemia than the controls (10/19 (52%) vs 7/32 (22%), relative risk 2.4, 95% confidence intervals (CI) 1.10 to 5.26). Third day serum bilirubin values (mean (SD)) were higher in the Down's syndrome neonates than in controls (214 +- 63 micromol/l vs 172 +- 54 micromol/l, respectively, p=0.015). Mean (SD) COHbc values were significantly higher in the Down's syndrome neonates than in controls (0.92 +- 0. 24% vs 0.63 +- 0.17%; p<0.0001). However, Down's syndrome neonates who became hyperbilirubinaemic had similar COHbc values to those who did not (0.87 +- 0.26% and 0.95 +- 0.23%, respectively). These values contrast with those of the controls, in whom a significant increase in COHbc was associated with hyperbilirubinaemia (0.74 +- 0. 15% vs 0.60 +- 0.16%, respectively; p<0.05). tHb values were similar in both groups. CONCLUSIONS: Down's syndrome neonates had a greater risk of hyperbilirubinaemia, and higher COHbc values, than controls. However, excessive bilirubin production could not be exclusively responsible for the hyperbilirubinaemia. By inference, decreased bilirubin elimination probably plays a greater part in its pathogenesis than in controls. Down's syndrome neonates may have abnormal erythropoiesis, leading to increased haem turnover. (+info)Validation of the end-expired method for measuring carboxyhaemoglobin levels for the use in occupational and environmental exposure studies. (5/461)
Carbon monoxide is one of the most common toxins encountered in work settings, the gas being emitted in situations where there is incomplete combustion of carbon-containing substances. Its acute and chronic health effects have been well-documented. While identification of dangerous situations and evaluation of control measures are conducted by environmental monitoring, the body burden due to inhalation of carbon monoxide is measured by an individual's blood carboxyhaemoglobin level. Carboxyhaemoglobin level can be measured directly from a blood sample or, indirectly, by measuring the end-expired carbon monoxide level and using the charts provided to read the corresponding carboxyhaemoglobin level. As the end-expired method is not an intervention method, and is therefore easy to conduct, it is being used widely in epidemiological studies and it could also be used for individual measurements. This study presents a better statistical method for validating the end-expired method than the correlation method used and described in previous studies. (+info)Methylene chloride poisoning in a cabinet worker. (6/461)
More than a million workers are at risk for methylene chloride exposure. Aerosol sprays and paint stripping may also cause significant nonoccupational exposures. After methylene chloride inhalation, significant amounts of carbon monoxide are formed in vivo as a metabolic by-product. Poisoning predominantly affects the central nervous system and results from both carboxyhemoglobin formation and direct solvent-related narcosis. In this report, we describe a case of methylene chloride intoxication probably complicated by exogenous carbon monoxide exposure. The worker's presentation of intermittent headaches was consistent with both methylene chloride intoxication and carbon monoxide poisoning. The exposures and symptoms were corroborated by elevated carboxyhemoglobin saturations and a workplace inspection that documented significant exposures to both methylene chloride and carbon monoxide. When both carbon monoxide and methylene chloride are inhaled, additional carboxyhemoglobin formation is expected. Preventive efforts should include education, air monitoring, and periodic carboxyhemoglobin determinations. Methylene chloride should never be used in enclosed or poorly ventilated areas because of the well-documented dangers of loss of consciousness and death. (+info)Effects of exposure to low concentrations of carbon monoxide on exercise performance and myocardial perfusion in young healthy men. (7/461)
OBJECTIVE: To assess the effects of exposure to low concentrations of carbon monoxide (CO), as commonly measured in atmospheric urban air pollution and certain occupational environments, on exercise performance and myocardial perfusion in young healthy men, and the possible need for tighter restrictions on ambient concentrations of CO. METHODS: 15 young, healthy non-smoking men, 18-35 years old, were exposed blindly and randomly to air or to a mixture of CO and air, followed by an exercise treadmill test with thallium heart scintigraphy. Blood was drawn for determination of carboxyhaemoglobin before and at the end of the exposure, and for lactic and pyruvic acid at the beginning and the end of the exercise test. The main outcome measures include the duration of the exercise test, the maximal effort expressed in metabolic equivalent units (METs), the mean plasma lactic to pyruvic acid ratio at the end of the ergometry, ECG changes in the exercise test, and perfusion deficits in thallium heart scintigraphy. RESULTS: At the end of exposure to CO, the mean (SD) blood carboxyhaemoglobin concentration rose from 0.59% (0.08%) to 5.12% (0.65%) (p < 0.0001). At the end of the exercise period, the mean (SD) plasma lactate/pyruvate ratio, which reflects the level of anaerobic metabolism (69.9 (5.9) after air and 75.9 (7.0) after CO), was not significantly different between the two experimental groups. Exercise induced electrocardiographic changes were noted in only one subject after exposure to CO. No arrhythmias were detected in any of the subjects. Significant differences were found in the mean duration of the exercise test (p = 0.0012) and the METs (p = 0.0001). The mean adjusted difference of exercise duration between exposure to air and CO was 1.52 minutes 95% confidence interval (95% CI) 0.73 to 2.32 minutes. The mean adjusted difference of METs between exposure to air and CO was 2.04 95% CI 1.33 to 2.76. The models for duration of exercise and METs showed no significant sequence and period effects. Thallium myocardial perfusion imaging disclosed normal perfusion in all regions of the heart, with no significant differences in perfusion between the two exercise tests (after air or CO). CONCLUSION: Acute exposure to a low concentration of CO which produces blood carboxyhaemoglobin concentrations of 4%-6% significantly decreases exercise performance in young healthy men. No ischaemic electrocardiographic changes or disturbances in myocardial perfusion were found by graded exercise with thallium scintigraphy. Our findings suggest that pollution of atmospheric air by CO at concentrations which are commonly found in urban and industrial environments may exert an adverse effect on skeletal muscles, manifesting as decreased exercise performance. (+info)UV resonance raman spectra of ligand binding intermediates of sol-gel encapsulated hemoglobin. (8/461)
We report for the first time specific conformational changes for a homogeneous population of ligand-bound adult deoxy human hemoglobin A (HbA) generated by introducing CO into a sample of deoxy-HbA with the effector, inositol hexaphosphate, encapsulated in a porous sol-gel. The preparation of ligand-bound deoxy-HbA results from the speed of ligand diffusion relative to globin conformational dynamics within the sol-gel (1). The ultraviolet resonance Raman (UVRR) difference spectra obtained reveal that E helix motion is initiated upon ligand binding, as signaled by the appearance of an alpha14beta15 Trp W3 band difference at 1559 cm(-1). The subsequent appearance of Tyr (Y8a and Y9a) and W3 (1549 cm(-1)) UVRR difference bands suggest conformational shifts for the penultimate Tyralpha140 on the F helix, the "switch" region Tyralpha42, and the "hinge" region Trpbeta37. The UVRR results expose a sequence of conformational steps leading up to the ligation-induced T to R quaternary structure transition as opposed to a single, concerted switch. More generally, this report demonstrates that sol-gel encapsulation of proteins can be used to study a sequence of specific conformational events triggered by substrate binding because the traditional limitation of substrate diffusion times is overcome. (+info)
Carboxyhemoglobin and Methemoglobin as Markers of Postoperative Pulmonary Complications
Rapid estimation of carboxyhemoglobin by breath sampling in an emergency setting<...
Carboxyhaemoglobin levels in water-pipe and cigarette smokers
Measurement of Carboxyhemoglobin by Gas Chromatography as an Index of Hemolysis - Full Text View - ClinicalTrials.gov
Scandinavian Journal of Work, Environment & Health - Carbon monoxide in foundry air.
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Toxicity of Carbon Monoxide-Hydrogen Cyanide Gas Mixtures: Expose Concentration, Time-to-Incapacitation, Carboxyhemoglobin, and...
Spectrophotometric measurement of carboxyhemoglobin and methem...
The effect of feeding frequency and dose rate of nitrate supplements on blood haemoglobin fractions in Bos indicus cattle fed...
Hitchhikers Guide to the Galaxy on Carbon monoxide
Carbon monoxide - Wikipedia
CO poisoning: clinical features
A METHOD FOR THE DETERMINATION OF DIFFUSION CONSTANTS AND THE CALCULATION OF THE RADIUS AND WEIGHT OF THE HEMOGLOBIN MOLECULE |...
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Evaluation of nicotine, cotinine, thiocyanate, carboxyhemoglobin, and expired carbon monoxide as biochemical tobacco smoke...
Treatment of acute carbon-monoxide poisoning with therapeutic erythrocytapheresis: Clinical effects and results in 17 victims |...
Risk of Myocardial Infarction and Stroke in Smokers Is Related to Plasma Levels of Inflammation-Sensitive Proteins.
An analysis of carbon monoxide poisoning cases in Bursa, Turkey
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Alveolar carbon monoxide: A comparison of methods of measurement and a study of the effect of change in body posture | Clinical...
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Burns - CO poisoning Ddx
Non-invasive Measurement of Hemoglobin Concentration With Pulse Co-oximetry - Full Text View - ClinicalTrials.gov
New CO-oximetry Module for the ABL80 FLEX Blood Ga... ( WESTLAKE Ohio Aug. 4 /- Radiomete...)
RCSB PDB
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Hemoglobin
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Elevated carboxyhemoglobin in a marine mammal, the northern elephant seal | Scripps Institution of Oceanography, UC San Diego
Dozen construction workers hospitalized after possible carbon monoxide exposure
Protective effect of carbon monoxide inhalation for cold-preserved small intestinal grafts<...
Carbon Monoxide Poisonings Resulting from Open Air Exposures
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Cigar and pipe smoking and cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC). - Cancer...
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English
Carbon monoxide
Additionally, a noninvasive carboxyhemoglobin (SpCO) test method from Pulse CO-Oximetry exists and has been validated compared ... Concentrations as low as 667 ppm may cause up to 50% of the body's hemoglobin to convert to carboxyhemoglobin. A level of 50% ... Normal circulating levels in the blood are 0% to 3% saturation, i.e. the ratio of the amount of carboxyhaemoglobin present to ... This process produces a certain amount of carboxyhemoglobin in normal persons, even if they do not breathe any carbon monoxide ...
Carbon monoxide poisoning
A CO-oximeter can be used to determine carboxyhemoglobin levels. Pulse CO-oximeters estimate carboxyhemoglobin with a non- ... The ratio of carboxyhemoglobin to hemoglobin molecules in an average person may be up to 5%, although cigarette smokers who ... Carboxyhemoglobin levels have been shown to have a strong correlation with breath CO concentration. However, many of these ... This results following a recurrence of increased carboxyhemoglobin levels; this effect may be due to a late release of carbon ...
CO-oximeter
More recently, some 'pulse' or more precisely 'peripheral' oximeters have made it possible to estimate carboxyhemoglobin with ... carboxyhemoglobin and methemoglobin. Crit Care International, April-May, 8-9, 1995. Moran RF, The case for standardized ... as well as the dyshemoglobins such as carboxyhemoglobin (COHb) and methemoglobin (MetHb). The use of 'CO' rather than 'Co' or ' ... "Spectrophotometric measurement of carboxyhemoglobin and methemoglobin in blood". Clinical Chemistry. 25 (8): 1388-93. PMID ...
Iron
Hemoglobin bound to carbon monoxide is known as carboxyhemoglobin. This effect also plays a minor role in the toxicity of ... Gregory B. Vásquez; Xinhua Ji; Clara Fronticelli; Gary L. Gilliland (1998). "Human Carboxyhemoglobin at 2.2 Å Resolution: ...
Pulse oximetry
UK 2320566 Maisel WH, Lewis RJ (October 2010). "Noninvasive measurement of carboxyhemoglobin: how accurate is accurate enough ... By using additional wavelengths, it provides clinicians a way to measure the dyshemoglobins, carboxyhemoglobin, and ...
Breath carbon monoxide
This is known as "Fetal carboxyhaemoglobin" (%FCOHb). This level has also been found to be on average 1.8 times higher in the ... Maisel, William; Roger J. Lewis (2010). "apple Measurement of Carboxyhemoglobin: How Accurate is Accurate Enough?". Annals of ... carbon monoxide level has been shown to have a close relationship with the level of CO in the blood known as carboxyhaemoglobin ...
Respiratory tract infection
Zavorsky, Gerald S. (2012). "The rise in carboxyhemoglobin from repeated pulmonary diffusing capacity tests". Respiratory ...
Exhaust gas
It combines with hemoglobin to produce carboxyhemoglobin, which blocks the transport of oxygen. At concentrations above 1000ppm ...
Diffusing capacity for carbon monoxide
Expected DLCO is also affected by the amount of hemoglobin, carboxyhemoglobin, age and sex. The correction for hemoglobin is ...
Oxygen-hemoglobin dissociation curve
The reaction HbO2 + CO → HbCO + O2 almost irreversibly displaces the oxygen molecules forming carboxyhemoglobin; the binding of ... a person can suffer from severe tissue hypoxia while maintaining a normal pO2 because carboxyhemoglobin does not carry oxygen ...
Hypoxia (medical)
Wald, NJ; Idle, M; Boreham, J; Bailey, A (May 1981). "Carbon monoxide in breath in relation to smoking and carboxyhaemoglobin ...
Smoke inhalation
Weaver LK, Howe S, Hopkins R, Chan KJ (2000). "Carboxyhemoglobin half-life in carbon monoxide-poisoned patients treated with ...
Blood
... in carbon monoxide poisoning is bright red, because carbon monoxide causes the formation of carboxyhemoglobin. In cyanide ... because carbon monoxide irreversibly binds to hemoglobin to form carboxyhemoglobin, so that less hemoglobin is free to bind ...
Kleihauer-Betke test
... or carboxyhemoglobin. Methods developed by Schneider and Ludwig and Bartsch' are recommended. For determination of the ...
Arterial blood gas test
... carboxyhemoglobin, and methemoglobin. ABG testing is mainly used in pulmonology and critical-care medicine to determine gas ...
Heating, ventilation, and air conditioning
Carbon monoxide binds with hemoglobin in the blood, forming carboxyhemoglobin, reducing the blood's ability to transport oxygen ...
List of accidents and incidents involving the DC-3 since 2000
Both crew members were found to have high levels of carboxyhaemoglobin in their blood. The flight had departed from Points ...
Hypoxia (medical)
"Carbon monoxide in breath in relation to smoking and carboxyhaemoglobin levels". Thorax. 36 (5): 366-69. doi:10.1136/thx.36.5. ...
Carbon monoxide-releasing molecules
The average carboxyhemoglobin (CO-Hb) level in a non-smoker is between 0.2% and 0.85% CO-Hb (whereas a smoker may have between ... lyated bovine carboxyhemoglobin and maleimide PEG conjugated human carboxyhemoglobin. Porphyrin structures such as heme, hemin ... Carboxyhemoglobin can be infused to deliver CO. The most common approaches are based on polyethylene glycol (PEG)- ... Methylene chloride was the first organic CORM orally administered based on previous reports of carboxyhemoglobin formation via ...
Grinker myelinopathy
... while the standard oxygen treatment normalizes carboxyhemoglobin levels. Another preventative measure one can take is to be on ...
Dupont Plaza Hotel arson
"Analysis Of Carboxyhemoglobin And Cyanide In Blood From Victims Of The Dupont Plaza Hotel Fire In Puerto Rico" (PDF). Fire.nist ...
Metal carbonyl
Vásquez, G. B.; Ji, X.; Fronticelli, C.; Gilliland, G. L. (1998). "Human Carboxyhemoglobin at 2.2 Å Resolution: Structure and ... in part because of their ability to carbonylate hemoglobin to give carboxyhemoglobin, which prevents the binding of oxygen. The ...
Tobacco smoking
Turner, JA; Sillett, RW; McNicol, MW (1977). "Effect of cigar smoking on carboxyhemoglobin and plasma nicotine concentrations ...
Red blood cell
Hemoglobin also has a very high affinity for carbon monoxide, forming carboxyhemoglobin which is a very bright red in color. ...
Gaseous signaling molecules
This process produces a certain amount of carboxyhemoglobin in normal persons, even if they do not breathe any carbon monoxide ...
S7 Airlines Flight 778
One flight attendant was found with a total of 85% of carboxyhemoglobin concentration inside her blood, along with her ...
HVAC
Carbon monoxide binds with hemoglobin in the blood, forming carboxyhemoglobin, reducing the blood's ability to transport oxygen ...
Iron
A heme unit of human carboxyhemoglobin, showing the carbonyl ligand at the apical position, trans to the histidine residue.[147 ... Hemoglobin bound to carbon monoxide is known as carboxyhemoglobin. This effect also plays a minor role in the toxicity of ... "Human Carboxyhemoglobin at 2.2 Å Resolution: Structure and Solvent Comparisons of R-State, R2-State and T-State Hemoglobins" ...
Pulse oximetry
Maisel, William; Roger J. Lewis (2010). "Noninvasive Measurement of Carboxyhemoglobin: How Accurate is Accurate Enough?". ... carboxyhemoglobin, and methemoglobin along with total hemoglobin.[47] ...
Carboxyhemoglobin - Wikipedia
Carboxyhemoglobin or carboxyhaemoglobin (symbol COHb or HbCO) is a stable complex of carbon monoxide and hemoglobin (Hb) that ... Exposure to small concentrations of CO hinder the ability of Hb to deliver oxygen to the body, because carboxyhemoglobin forms ... This process produces a certain amount of carboxyhemoglobin in normal persons, even if they do not breathe carbon monoxide. ... Vásquez GB, Ji X, Fronticelli C, Gilliland GL (1998). "Human Carboxyhemoglobin at 2.2 Å Resolution: Structure and Solvent ...
Plus it
Variations in Carboxyhaemoglobin Levels in Smokers Br Med J 1974; 4 :736 ... Three experiments on smokers have been performed to determine variations in blood levels of carboxyhaemoglobin (COHb) ... Variations in Carboxyhaemoglobin Levels in Smokers. Br Med J 1974; 4 doi: https://doi.org/10.1136/bmj.4.5947.736 (Published 28 ...
Carboxyhemoglobin Elevation after Exposure to Dichloromethane | Science
Carboxyhemoglobin Elevation after Exposure to Dichloromethane. By Richard D. Stewart, Terrance N. Fisher, Michael J. Hosko, ... Carboxyhemoglobin Elevation after Exposure to Dichloromethane. By Richard D. Stewart, Terrance N. Fisher, Michael J. Hosko, ... Carboxyhemoglobin Elevation after Exposure to Dichloromethane Message Subject. (Your Name) has forwarded a page to you from ...
Evaluation of nicotine, cotinine, thiocyanate, carboxyhemoglobin, and expired carbon monoxide as biochemical tobacco smoke...
Measurement of Carboxyhemoglobin by Gas Chromatography as an Index of Hemolysis - Full Text View - ClinicalTrials.gov
Measurement of Carboxyhemoglobin by Gas Chromatography as an Index of Hemolysis. The safety and scientific validity of this ... Measurement of Carboxyhemoglobin by Gas Chromatography as an Index of Hemolysis in ABO-compatible and Incompatible Healthy Term ... A very accurate and reliable laboratory measure of red blood cell destruction is the plasma carboxyhemoglobin level (COHb). ...
COMPLICATIONS RELATED CARBOXYHEMOGLOBIN LEVELS IN SECOND HAND SMOKING PEDIATRIC TONSILLECTOMY PATIENTS - Full Text View -...
COMPLICATIONS RELATED CARBOXYHEMOGLOBIN LEVELS IN SECOND HAND SMOKING PEDIATRIC TONSILLECTOMY PATIENTS. The safety and ... Correlation between carboxyhemoglobin levels and pain of the second hand smoking children [ Time Frame: postoperative 24 hours ... Correlation between carboxyhemoglobin levels of the second hand smoking children and intraoperative bleeding volume [ Time ... The purpose of this study was to determine whether high carboxyhemoglobin level is a risk factor for postoperative adverse ...
Method for noninvasive (in-vivo) total hemoglobin, oxyhemogolobin, deoxyhemoglobin, carboxyhemoglobin and methemoglobin...
Method for noninvasive (in-vivo) total hemoglobin, oxyhemogolobin, deoxyhemoglobin, carboxyhemoglobin and methemoglobin ... At 548 nm, there is a triple isosbestic point for oxy-, deoxy- and carboxyhemoglobin. At this point these species have an ... In addition, a triple isosbestic point for oxy-, deoxy-, and carboxyhemoglobin is apparent at 548 nm. At this point, the ... The Coming Co-Oximeter 2500 measures total hemoglobin, oxyhemoglobin, deoxyhemoglobin, carboxyhemoglobin, methemoglobin and ...
Carboxyhaemoglobin levels in workers in Leicestershire garages. | Occupational & Environmental Medicine
Carboxyhaemoglobin levels in water-pipe and cigarette smokers
The carboxyhaemoglobin (COHb) level in the blood (half-life 2 -6 hours) after inhalation of CO will depend on concentrations of ... Carboxyhaemoglobin concentrations in smokers of zheesha and cigarettes in Saudi Arabia. BMJ 1985; 291: 1768-1770. [ Links ]. ... AIM: We aimed to measure carboxyhaemoglobin (COHb) blood levels before and after water-pipe and cigarette smoking sessions. ...
Prevalence of Causes of Symptom: Elevated carboxyhaemoglobin - RightDiagnosis.com
Prevalence or incidence of diseases and medical conditions possibly causing symptom Elevated carboxyhaemoglobin as a symptom, ... Related medical articles for symptom Elevated carboxyhaemoglobin: *Symptom: Elevated carboxyhaemoglobin *Possible causes of ... Elevated carboxyhaemoglobin type of: Red blood cell symptoms (849 causes), Blood symptoms (2053 causes), Abnormal blood test ... Symptoms related to Elevated carboxyhaemoglobin: Carbon monoxide poisoning, Carbon dioxide, Oxy haemoglobin, Suffocation (3 ...
Elevated carboxyhemoglobin in a marine mammal, the northern elephant seal | Scripps Institution of Oceanography, UC San Diego
Is alveolar carbon monoxide an unreliable index of carboxyhaemoglobin changes during smoking in man? | Clinical Science |...
Is alveolar carbon monoxide an unreliable index of carboxyhaemoglobin changes during smoking in man? Andrew R. Guyatt; Andrew R ... 2. In seven subjects where the carboxyhaemoglobin level was raised by breathing a 2% CO gas mixture, the alveolar CO and ... The mean relative boosts ([post value-pre value]/[pre + post]/2) for alveolar CO and carboxyhaemoglobin were 7.7% and 20.3%, ... 3. We conclude that alveolar CO measurements give a useful estimate of carboxyhaemoglobin level if the subject has not smoked ...
Carboxyhemoglobin and Methemoglobin as Markers of Postoperative Pulmonary Complications
Postoperative carboxyhemoglobin was higher in smokers compared to control non-smokers group (p = 0.000). On the other hand, ... In both groups carboxyhemoglobin and methemoglobin levels were determined preoperatively, after preoxygenation, and one hour ... Determination of the level of carboxyhemoglobin and methemoglobin can identify patients with increased risk for development of ... we cannot confirm the hypothesis that carboxyhemoglobin and methemoglobin can serve as predictors for postoperative pulmonary ...
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Spectrophotometric measurement of carboxyhemoglobin and methem...
Spectrophotometric measurement of carboxyhemoglobin and methemoglobin in blood.: This paper describes separate ... Spectrophotometric measurement of carboxyhemoglobin and methemoglobin in blood.. Authors * Rodkey, F L ... This paper describes separate spectrophotometric procedures for rapidly measuring carboxyhemoglobin (COHb) and methemoglobin ( ...
Carboxyhemoglobin definition, causes, symptoms, test, levels & treatment
What are normal and elevated carboxyhemoglobin levels. Carboxyhemoglobin treatment ... What is carboxyhemoglobin. Carboxyhemoglobin (COHb) is formed by the binding of carbon monoxide (CO) to hemoglobin (Hb). High ... Carboxyhemoglobin sources. Physiologic. Carboxyhemoglobin levels increase as a result of hemolysis. Carbon monoxide is a ... The clearance of carboxyhemoglobin in methylene chloride poisoning is prolonged. The half-life of carboxyhemoglobin in this ...
Toxicity of Carbon Monoxide-Hydrogen Cyanide Gas Mixtures: Expose Concentration, Time-to-Incapacitation, Carboxyhemoglobin, and...
... but the resulting concentrations of carboxyhemoglobin COHb and blood cyanide CN- at incapacitation are not well defined. These ... Toxicity of Carbon Monoxide-Hydrogen Cyanide Gas Mixtures: Expose Concentration, Time-to-Incapacitation, Carboxyhemoglobin, and ... but the resulting concentrations of carboxyhemoglobin COHb and blood cyanide CN- at incapacitation are not well defined. These ...
EF | definition of EF by Medical dictionary
Electronic Code of Federal Regulations (eCFR)
864.7425 Carboxyhemoglobin assay.. (a) Identification. A carboxyhemoglobin assay is a device used to determine the ... 864.7425 Carboxyhemoglobin assay.. §864.7440 Electrophoretic hemoglobin analysis system.. §864.7455 Fetal hemoglobin assay.. § ... carboxyhemoglobin (the compound formed when hemoglobin is exposed to carbon monoxide) content of human blood as an aid in the ...
Carbon monoxide poisoning
Carboxyhemoglobin. Levels of carbon monoxide bound in the blood can be determined by measuring carboxyhemoglobin, which is a ... Normal carboxyhemoglobin levels in an average person are less than 5%, whereas cigarette smokers (two packs/day) may have ... Serious toxicity is often associated with carboxyhemoglobin levels above 25%, and the risk of fatality is high with levels over ... Hemoglobin acquires a bright red color when converted to carboxyhemoglobin, so a casualty of CO poisoning is described in ...
NIOSHTIC-2 Publications Search - 00127268 - Health hazard evlauation report: HETA-81-299-1201, United States Steel Company-...
Aggravation of exercise performance in patients with anemia by 3% carboxyhemoglobin<...
... carboxyhemoglobin. Together they form a unique fingerprint. * Carboxyhemoglobin Medicine & Life Sciences ... Mean carboxyhemoglobin levels increased from 2.14 to 3.38% after breathing CO and decreased from 2.15 to 1.86% after breathing ... Mean carboxyhemoglobin levels increased from 2.14 to 3.38% after breathing CO and decreased from 2.15 to 1.86% after breathing ... Mean carboxyhemoglobin levels increased from 2.14 to 3.38% after breathing CO and decreased from 2.15 to 1.86% after breathing ...
Gas Education | Fundamentals of Gas Detectors | Industrial Scientific
Carbon Monoxide Safety | Taylor, MI
Carboxyhemoglobin (COHb). Carboxyhemoglobin can cause headaches, fatigue, nausea, dizzy spells, confusion and irritability. ... When CO is breathed in by an individual, it accumulates in the blood and forms a toxic compound known as carboxyhemoglobin ( ... seek medical treatment or get a carboxyhemoglobin level blood test for CO poisoning. Some of the symptoms can also include are: ...
Ligand dynamics in the photodissociation of carboxyhemoglobin by subpicosecond transient infrared spectroscopy<...
Rothberg, L. ; Jedju, T. M. ; Austin, R. H. / Ligand dynamics in the photodissociation of carboxyhemoglobin by subpicosecond ... Rothberg, L., Jedju, T. M., & Austin, R. H. (1990). Ligand dynamics in the photodissociation of carboxyhemoglobin by ... Rothberg, L, Jedju, TM & Austin, RH 1990, Ligand dynamics in the photodissociation of carboxyhemoglobin by subpicosecond ... Fingerprint Dive into the research topics of Ligand dynamics in the photodissociation of carboxyhemoglobin by subpicosecond ...
January 1977 - Volume 59 - Issue 1 : Plastic and Reconstructive Surgery
Hemoglobin derivatives: MedlinePlus Medical Encyclopedia
The carboxyhemoglobin test is used to diagnose carbon monoxide poisoning. It is also used to detect changes in hemoglobin that ... Carboxyhemoglobin: An abnormal form of hemoglobin that has attached to carbon monoxide instead of oxygen or carbon dioxide. ... Carboxyhemoglobin -- less than 1.5% (but may be as high as 9% in smokers) ...
Recurrent Acute Life-threatening Events and Lactic Acidosis Caused by Chronic Carbon Monoxide Poisoning in an Infant | American...
carboxyhemoglobin • LCHAD = long-chain 3-OH acyl CoA dehydrogenase. The incidence of carbon monoxide (CO) poisoning is ∼3500 to ... 1987) Carboxyhemoglobin levels in patients with flu-like symptoms. Ann Emerg Med 16:782-786. ... A review of cooximetry values from her previous hospitalizations revealed slightly elevated carboxyhemoglobin (COHb) levels. ...
COHb20
- Carboxyhemoglobin or carboxyhaemoglobin (symbol COHb or HbCO) is a stable complex of carbon monoxide and hemoglobin (Hb) that forms in red blood cells upon contact with carbon monoxide (CO). Carboxyhemoglobin is often mistaken for the compound formed by the combination of carbon dioxide and hemoglobin, which is actually carbaminohemoglobin. (wikipedia.org)
- Supplemental oxygen takes advantage of Le Chatelier's principle to quicken the decomposition of carboxyhemoglobin back to hemoglobin: HbCO + O2 ⇌ Hb + CO + O2 ⇌ HbO2 + CO COHb increases risk of blood clot. (wikipedia.org)
- Three experiments on smokers have been performed to determine variations in blood levels of carboxyhaemoglobin (COHb) throughout the day and night and whether a random measurement of COHb gives a true estimation of a smoker's mean COHb level. (bmj.com)
- 149 smokers, 87 non-smokers) plasma nicotine (pnic), cotinine (pcot) and thiocyanate (pSCN), urinary creatinine ratios of nicotine (unic), cotinine (ucot) and thiocyanate (uSCN) as well as carboxyhemoglobin (COHb) and expired carbon monoxide (COex) were determined. (nih.gov)
- A very accurate and reliable laboratory measure of red blood cell destruction is the plasma carboxyhemoglobin level (COHb). (clinicaltrials.gov)
- We aimed to measure carboxyhaemoglobin (COHb) blood levels before and after water-pipe and cigarette smoking sessions. (scielo.org.za)
- The carboxyhaemoglobin (COHb) level in the blood (half-life 2 -6 hours) after inhalation of CO will depend on concentrations of inspired CO, duration of exposure, pulmonary ventilation and the COHb level before the inhalation. (scielo.org.za)
- However, high concentrations of carboxyhemoglobin (COHb), formed by CO binding to hemoglobin, potentially prevent adequate O-2 delivery to tissues by lowering arterial O-2 content. (ucsd.edu)
- This paper describes separate spectrophotometric procedures for rapidly measuring carboxyhemoglobin (COHb) and methemoglobin (MetHb) in blood. (mysciencework.com)
- Carboxyhemoglobin (COHb) is formed by the binding of carbon monoxide (CO) to hemoglobin (Hb). (healthjade.net)
- Carboxyhemoglobin (COHb) is a stable complex of carbon monoxide (CO) that forms in red blood cells when carbon monoxide is inhaled. (healthjade.net)
- Exposures to CO-HCN mixtures have demonstrated that these gases have additive effects producing shorter times to incapacitation, but the resulting concentrations of carboxyhemoglobin COHb and blood cyanide CN- at incapacitation are not well defined. (dtic.mil)
- When CO is breathed in by an individual, it accumulates in the blood and forms a toxic compound known as carboxyhemoglobin ( COHb ). (cityoftaylor.com)
- We examined associations between carboxyhemoglobin (COHb) serum concentration-an exposure proxy for carbon monoxide (CO)-ambient CO, and ARI in both cohorts. (springer.com)
- In addition, we determined carbon monoxide and found high amounts in the smoke being causative for high levels of carboxyhemoglobin (COHb) in the blood of smokers. (nih.gov)
- Not only does the hemoglobin prefer CO, it holds on to the CO much more tightly, forming a complex called carboxyhemoglobin (COHb). (encyclopedia.com)
- Participation of hypoxic hypoxia in low COHb (Carboxyhemoglobin) concentrations frequently observed in fire victims was examined using rats and rabbits exposed to low-O2 and CO gas mixtures. (biomedsearch.com)
- Readily absorbed through the lungs, carbon monoxide binds to hemoglobin as carboxyhemoglobin (COHb). (cmaj.ca)
- In case of CO poisoning, the reduced oxygen-carrying capacity of the blood, impairment of the cellular respiratory chain, and immune-modulating processes can lead to tissue injury in the myocardium and brain even after lowering of the carboxyhemoglobin (COHb) concentration. (aerzteblatt.de)
- five had elevated carboxyhemoglobin (COHb) levels. (cdc.gov)
Carbon19
- This process produces a certain amount of carboxyhemoglobin in normal persons, even if they do not breathe carbon monoxide. (wikipedia.org)
- The purpose of this study was to determine whether high carboxyhemoglobin level is a risk factor for postoperative adverse events in children exposured to carbon monoxide, especially enviromental tobacco smoke. (clinicaltrials.gov)
- Is alveolar carbon monoxide an unreliable index of carboxyhaemoglobin changes during smoking in man? (portlandpress.com)
- 1. We measured alveolar carbon monoxide (CO) after a 20 s breath-holding period and carboxyhaemoglobin both before and after smoking a cigarette on 500 occasions (101 individuals). (portlandpress.com)
- Carboxyhemoglobin should be measured if carbon monoxide or methylene chloride poisoning is suspected. (healthjade.net)
- Carboxyhemoglobin is also useful in monitoring the treatment of carbon monoxide poisoning. (healthjade.net)
- Approximately 85% of absorbed carbon monoxide binds with hemoglobin and remains in the intravascular compartment as carboxyhemoglobin. (healthjade.net)
- Carbon monoxide poisoning needs a high concentration of O2 to replace the carboxyhemoglobin. (healthjade.net)
- The half-life of carboxyhemoglobin in this setting is approximately 13 hours because of ongoing carbon monoxide production from methylene chloride metabolism in the liver. (healthjade.net)
- The carboxyhemoglobin test is used to diagnose carbon monoxide poisoning . (medlineplus.gov)
- Carboxyhemoglobin: An abnormal form of hemoglobin that has attached to carbon monoxide instead of oxygen or carbon dioxide. (medlineplus.gov)
- Breath measurement of carbon monoxide (CO) can be rapidly performed in the emergency department setting by a reliable method that closely approximates carboxyhemoglobin. (elsevier.com)
- The amount of conversion to carbon monoxide is significant as measured by the concentration of carboxyhemoglobin, up to 12% measured in the blood following occupational exposure of up to 610 ppm. (osha.gov)
- Since exposure to MC also increases the carboxyhemoglobin level in the blood, ambient carbon monoxide levels would have an additive effect on that carboxyhemoglobin level. (osha.gov)
- The gas was first identified by Joseph Priestley in the eighteenth century, but it was Claude Bernard in 1870 who discovered the affinity between carbon monoxide and haemoglobin which accounts for its deadliness: carboxyhaemoglobin is formed and oxygen transport from the lungs to the tissues disrupted. (encyclopedia.com)
- In 1895 J. S. Haldane demonstrated that the formation of carboxyhaemoglobin is an equilibrium reaction which depends upon the relative partial pressures of carbon monoxide and oxygen in inspired gas. (encyclopedia.com)
- Since air contains 21% oxygen this means that only 0.1% carbon monoxide in the air will eventually lead to 50% of the haemoglobin being combined to form carboxyhaemoglobin. (encyclopedia.com)
- Therefore, the objective was to verify the association between environmental carbon monoxide and carboxyhemoglobin levels among smoking and non- smoking motorcycle taxi drivers. (bvsalud.org)
- A longitudinal epidemiological study was carried out with 95 motorcycle taxi drivers with measurement of the environmental carbon monoxide , carboxyhemoglobin in the exhaled air in three moments with interval of six months, between June 2014 and March 2015, as well as sociodemographic and occupational characteristics of these workers . (bvsalud.org)
Methemoglobin5
- 5. The method of claim 3 wherein the hemoglobin species is selected from the group consisting of: oxyhemoglobin, deoxyhemoglobin, carboxyhemoglobin, methemoglobin, and sulfhemoglobin. (freepatentsonline.com)
- Determination of the level of carboxyhemoglobin and methemoglobin can identify patients with increased risk for development of postoperative pulmonary complications. (ommegaonline.org)
- In both group's carboxyhemoglobin and methemoglobin levels were determined preoperatively, after preoxygenation, and one hour after completing the anesthesia. (ommegaonline.org)
- however, we cannot confirm the hypothesis that carboxyhemoglobin and methemoglobin can serve as predictors for postoperative pulmonary complications. (ommegaonline.org)
- Spectrophotometric measurement of carboxyhemoglobin and methemoglobin in blood. (mysciencework.com)
Hemoglobin3
- 2. The ratio of a component to the total, e.g., the substance fraction of carboxyhemoglobin (relative to the total hemoglobin). (thefreedictionary.com)
- On the other hand, CO combines with hemoglobin to produce carboxyhemoglobin, which occupies the space in hemoglobin that normally carries oxygen, but it is ineffective for delivering oxygen to bodily tissues. (zaslavsky.com.ua)
- Apart from hemoglobin breakdown, heme compounds of cell membrane and mitochondrial enzymes may become the source of endogenous CO and carboxyhemoglobin production. (zaslavsky.com.ua)
Smokers4
- Postoperative carboxyhemoglobin was higher in smokers compared to control non-smokers group (p = 0.000). (ommegaonline.org)
- Smokers: Up to 10%-15% carboxyhemoglobin. (healthjade.net)
- carboxyhemoglobin levels among smokers and non-smokers were high in the winter, fair in the spring and low in the autumn. (bvsalud.org)
- Environmental pollution represented different levels in the four seasons of the year and significant association with carboxyhemoglobin levels.Thecarboxyhemoglobin levels were higher among smokers , with statistical significance between winter and fall seasons , while non-smokers presented normal levels, whatconfirms the direct influence of tobacco in carboxyhemoglobin levels. (bvsalud.org)
Oxygen5
- Exposure to small concentrations of CO hinder the ability of Hb to deliver oxygen to the body, because carboxyhemoglobin forms more readily than does oxyhemoglobin (HbO2). (wikipedia.org)
- With hyperbaric oxygen at 3 times atmospheric pressure, carboxyhemoglobin elimination half-life can be reduced even further, to about 20-30 minutes. (healthjade.net)
- Because carboxyhaemoglobin does not carry oxygen, a level of 50% means that the oxygen carrying capacity of the blood is reduced by 50% and there is a corresponding reduction in the ability to perform maximum exercise. (encyclopedia.com)
- The presence of carboxyhaemoglobin also diminishes the oxygen held by the normal haemoglobin, which further compounds the hypoxic effect. (encyclopedia.com)
- Oxygen saturation accuracy in conditions of elevated carboxyhemoglobin. (clinicaltrials.gov)
Estimation of carboxyhemoglobin1
- We have studied the results of these investigations by means of the evaluation of CO production activity and the estimation of carboxyhemoglobin content in patient blood and СO in expiratory air. (zaslavsky.com.ua)
Levels8
- Also we want to measure bleeding volume and compare it with the carboxyhemoglobin levels. (clinicaltrials.gov)
- Carboxyhaemoglobin levels in workers in Leicestershire garages. (bmj.com)
- Blood carboxyhaemoglobin (HbCO%) levels were measured in 61 workers in 35 garages in Leicester and Leicestershire. (bmj.com)
- High carboxyhemoglobin levels can be physiologic or pathologic. (healthjade.net)
- Carboxyhemoglobin levels increase as a result of hemolysis. (healthjade.net)
- One approach has been to use direct CO inhalation therapy at concentrations that increase carboxyhemoglobin levels to 25% after CO inhalation. (asnjournals.org)
- The study verifies accuracy of a new pulse co-oximeter in the presence of elevated carboxyhemoglobin levels. (clinicaltrials.gov)
- Carboxyhemoglobin levels in patients with flu-like symptoms. (mja.com.au)
HbCO1
- Objective To investigate the effect of conventional preseratives on the stability of carboxyhemoglobin (HbCO)in the stored blood samples. (bvsalud.org)
Nonsmokers1
- Hence, in the absence of clinical heart or lung disease, increasing carboxyhemoglobin concentrations aggravate exercise performance in nonsmokers with chronic anemia. (elsevier.com)
Venous1
- A low baseline level of 1%-3% carboxyhemoglobin in venous blood is detectable in all people from endogenous production. (cmaj.ca)
Measurement2
- Measurement of Carboxyhemoglobin by Gas Chromatography as an Index of Hemolysis in ABO-compatible and Incompatible Healthy Term Newborn Infants. (clinicaltrials.gov)
- Spectrophotometric measurement of carboxyhemoglobin and methem. (mysciencework.com)
Poisoning is suspected1
- Perform carboxyhemoglobin (COHgb) testing when CO poisoning is suspected. (cdc.gov)
Methylene chloride1
- The clearance of carboxyhemoglobin in methylene chloride poisoning is prolonged. (healthjade.net)
Symptoms1
- If the family's (or pet's) symptoms decrease when away from the house, seek medical treatment or get a carboxyhemoglobin level blood test for CO poisoning. (cityoftaylor.com)
Inhalation1
- The inhalation of tobacco smoke can substantially raise the level of carboxyhemoglobin in the blood. (ommegaonline.org)
Pulse1
- The diagnosis of CO poisoning is based on history and examination, in conjunction with an elevated carboxyhaemoglobin level determined using pulse CO-oximetry, arterial blood gas analysis or CO breath testing. (mja.com.au)
Abstract1
- abstract = "Time-resolved infrared spectroscopy with 0.5-ps resolution is used to track the evolution of the CO stretching vibration after visible photoexcitation of carboxyhemoglobin in water at room temperature. (princeton.edu)
PATIENTS4
- Sketch, Michael H. / Aggravation of exercise performance in patients with anemia by 3% carboxyhemoglobin . (elsevier.com)
- Currently, many investigators consider an endogenous CO and carboxyhemoglobin production in critical states as a compensatory mechanism that promotes cytoprotection and contributes to patients' survivability. (zaslavsky.com.ua)
- Carboxyhemoglobin blood concentration no more than 4 % was presented in the majority of foreign investigations in patients in critical states. (zaslavsky.com.ua)
- All the patients were delivered to emergency department with normal carboxyhemoglobin blood concentration. (zaslavsky.com.ua)
Tissue1
- Thus, excessive endogenous CO production and excessive carboxyhemoglobin generation may play a significant role in tissue damage and multiorgan dysfunction formation. (zaslavsky.com.ua)
Forms1
- This forms carboxyhemoglobin. (news-medical.net)
Significant1
- The blood CO concentrations after the working shift showed a slight increase compared to prework values, but no significant trend was noted in carboxyhemoglobin concentrations. (cdc.gov)
Increase1
- Fast fluid resuscitation, hypertonic solution use, epinephrine administration were associated with increase of the blood pressure, perfusion index (PI) and carboxyhemoglobin blood concentration. (zaslavsky.com.ua)
Breathing room1
- The half-life of carboxyhemoglobin in an individual breathing room air is approximately 300 minutes. (healthjade.net)
Effects1
- Dose-Effects Functions for Carboxyhemoglobin and Behavior. (epa.gov)