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CarboxyhemoglobinCarbon Monoxide PoisoningMethemoglobinCarbon MonoxideSulfhemoglobinOximetryMethylene ChlorideHemoglobinsSmoke Inhalation InjuryMethemoglobinemiaOxyhemoglobinsBlood Gas Monitoring, TranscutaneousDithioniteBarium CompoundsPotassium CompoundsChromatography, GasSpectrophotometryPhotolysisSmokingCotinineThiocyanatesPeriodicals as TopicNicotineErythroblastosis, FetalABO Blood-Group SystemBlood Group IncompatibilityJaundiceTarsSeals, EarlessOceanographyPinnipediaDivingLung DiseasesThoracoplastyAnesthesia, IntratrachealBack MusclesHydrogen CyanideCyanides
Carboxyhemoglobin
Carbon Monoxide Poisoning
Toxic asphyxiation due to the displacement of oxygen from oxyhemoglobin by carbon monoxide.
Methemoglobin
Carbon Monoxide
Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
Sulfhemoglobin
Oximetry
The determination of oxygen-hemoglobin saturation of blood either by withdrawing a sample and passing it through a classical photoelectric oximeter or by electrodes attached to some translucent part of the body like finger, earlobe, or skin fold. It includes non-invasive oxygen monitoring by pulse oximetry.
Methylene Chloride
A chlorinated hydrocarbon that has been used as an inhalation anesthetic and acts as a narcotic in high concentrations. Its primary use is as a solvent in manufacturing and food technology.
Hemoglobins
The oxygen-carrying proteins of ERYTHROCYTES. They are found in all vertebrates and some invertebrates. The number of globin subunits in the hemoglobin quaternary structure differs between species. Structures range from monomeric to a variety of multimeric arrangements.
Smoke Inhalation Injury
Pulmonary injury following the breathing in of toxic smoke from burning materials such as plastics, synthetics, building materials, etc. This injury is the most frequent cause of death in burn patients.
Methemoglobinemia
The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed)
Oxyhemoglobins
A compound formed by the combination of hemoglobin and oxygen. It is a complex in which the oxygen is bound directly to the iron without causing a change from the ferrous to the ferric state.
Blood Gas Monitoring, Transcutaneous
The noninvasive measurement or determination of the partial pressure (tension) of oxygen and/or carbon dioxide locally in the capillaries of a tissue by the application to the skin of a special set of electrodes. These electrodes contain photoelectric sensors capable of picking up the specific wavelengths of radiation emitted by oxygenated versus reduced hemoglobin.
Dithionite
Dithionite. The dithionous acid ion and its salts.
Barium Compounds
Inorganic compounds that contain barium as an integral part of the molecule.
Potassium Compounds
Inorganic compounds that contain potassium as an integral part of the molecule.
Chromatography, Gas
Fractionation of a vaporized sample as a consequence of partition between a mobile gaseous phase and a stationary phase held in a column. Two types are gas-solid chromatography, where the fixed phase is a solid, and gas-liquid, in which the stationary phase is a nonvolatile liquid supported on an inert solid matrix.
Spectrophotometry
The art or process of comparing photometrically the relative intensities of the light in different parts of the spectrum.
Photolysis
Chemical bond cleavage reactions resulting from absorption of radiant energy.
Smoking
Inhaling and exhaling the smoke of burning TOBACCO.
Cotinine
The N-glucuronide conjugate of cotinine is a major urinary metabolite of NICOTINE. It thus serves as a biomarker of exposure to tobacco SMOKING. It has CNS stimulating properties.
Thiocyanates
Organic derivatives of thiocyanic acid which contain the general formula R-SCN.
Periodicals as Topic
A publication issued at stated, more or less regular, intervals.
Nicotine
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
Erythroblastosis, Fetal
A condition characterized by the abnormal presence of ERYTHROBLASTS in the circulation of the FETUS or NEWBORNS. It is a disorder due to BLOOD GROUP INCOMPATIBILITY, such as the maternal alloimmunization by fetal antigen RH FACTORS leading to HEMOLYSIS of ERYTHROCYTES, hemolytic anemia (ANEMIA, HEMOLYTIC), general edema (HYDROPS FETALIS), and SEVERE JAUNDICE IN NEWBORN.
ABO Blood-Group System
The major human blood type system which depends on the presence or absence of two antigens A and B. Type O occurs when neither A nor B is present and AB when both are present. A and B are genetic factors that determine the presence of enzymes for the synthesis of certain glycoproteins mainly in the red cell membrane.
Blood Group Incompatibility
An antigenic mismatch between donor and recipient blood. Antibodies present in the recipient's serum may be directed against antigens in the donor product. Such a mismatch may result in a transfusion reaction in which, for example, donor blood is hemolyzed. (From Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984).
Jaundice
A clinical manifestation of HYPERBILIRUBINEMIA, characterized by the yellowish staining of the SKIN; MUCOUS MEMBRANE; and SCLERA. Clinical jaundice usually is a sign of LIVER dysfunction.
Tars
Viscous materials composed of complex, high-molecular-weight compounds derived from the distillation of petroleum or the destructive distillation of wood or coal. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Seals, Earless
The family Phocidae, suborder PINNIPEDIA, order CARNIVORA, comprising the true seals. They lack external ears and are unable to use their hind flippers to walk. It includes over 18 species including the harp seal, probably the best known seal species in the world.
Oceanography
The science that deals with the ocean and its phenomena. (Webster, 3d ed)
Pinnipedia
The suborder of aquatic CARNIVORA comprising the WALRUSES; FUR SEALS; SEA LIONS; and EARLESS SEALS. They have fusiform bodies with very short tails and are found on all sea coasts. The offspring are born on land.
Diving
An activity in which the organism plunges into water. It includes scuba and bell diving. Diving as natural behavior of animals goes here, as well as diving in decompression experiments with humans or animals.
Lung Diseases
Pathological processes involving any part of the LUNG.
Thoracoplasty
Surgical removal of ribs, allowing the chest wall to move inward and collapse a diseased lung. (Dorland, 28th ed)
Anesthesia, Intratracheal
Back Muscles
Musculature of the BACK.
Hydrogen Cyanide
Hydrogen cyanide (HCN); A toxic liquid or colorless gas. It is found in the smoke of various tobacco products and released by combustion of nitrogen-containing organic materials.
Cyanides
Inorganic salts of HYDROGEN CYANIDE containing the -CN radical. The concept also includes isocyanides. It is distinguished from NITRILES, which denotes organic compounds containing the -CN radical.

Role of nitric oxide-derived oxidants in vascular injury from carbon monoxide in the rat. (1/461)

Studies were conducted with rats to investigate whether exposure to CO at concentrations frequently found in the environment caused nitric oxide (NO)-mediated vessel wall changes. Exposure to CO at concentrations of 50 parts per million or higher for 1 h increased the concentration of nitrotyrosine in the aorta. Immunologically reactive nitrotyrosine was localized in a discrete fashion along the endothelial lining, and this was inhibited by pretreatment with the NO synthase (NOS) inhibitor Nomega-nitro-L-arginine methyl ester (L-NAME). The CO-induced elevations of aortic nitrotyrosine were not altered by neutropenia or thrombocytopenia, and CO caused no change in the concentration of endothelial NOS. Consequences from NO-derived stress on the vasculature included an enhanced transcapillary efflux of albumin within the first 3 h after CO exposure and leukocyte sequestration that became apparent 18 h after CO exposure. Oxidized plasma low-density lipoprotein was found immediately after CO exposure, but this was not inhibited by L-NAME pretreatment. We conclude that exposure to relatively low CO concentrations can alter vascular status by several mechanisms and that many changes are linked to NO-derived oxidants.  (+info)

High predictive value of red cell volume measurement using carboxy-haemoglobin in a rabbit model of haemorrhage. (2/461)

We have studied the accuracy of blood volume measurements using carbon monoxide (CO)-labelled haemoglobin (COHb) injection and dilution (CO method) by comparing changes in red cell volume (RCV) measured using the CO method and 51Cr-labelled erythrocyte dilution (51Cr method) in a haemorrhage and infusion model in rabbits. RCV was measured repeatedly using the CO method at four different blood volume stages (stages I-IV). At stages I and IV, RCV was measured simultaneously using the 51Cr method. In comparing the sum of the circulating RCV and extracted RCV (SUM RCV) using the CO method, the values were almost equal and there were no significant differences between the values at the four stages. In comparing circulating RCV measured using the CO method and the 51Cr method, mean difference between the two methods was 0.80 (SD 0.76) ml kg-1 or 4.7 (4.6)%, and a positive correlation was observed (r = 0.91). We conclude that the CO method can be used to measure blood volume during perioperative periods in infants because it avoids use of a radioactive tracer, is simple and repeated measurements are possible.  (+info)

A physiological model for predicting carboxyhemoglobin formation from exposure to carbon monoxide in rats. (3/461)

A time-dependent simulation model, based on the Coburn-Forster-Kane equation, was written in Advanced Continuous Simulation Language to predict carboxyhemoglobin (HbCO) formation and dissociation in F-344 rats during and after exposure to 500 parts/million CO for 1 h. Blood-gas analysis and CO-oximetry were performed on samples collected during exposure and off-gassing of CO. Volume displacement plethysmography was used to measure minute ventilation (VE) during exposure. CO diffusing capacity in the lung (DLCO) was also measured. Other model parameters measured in the animals included blood pH, total blood volume, and Hb concentration. Comparisons between model predictions using values for VE, DLCO, and the Haldane coefficient cited in the literature and predictions using measured VE, DLCO, and calculated Haldane coefficient for individual animals were made. General model predictions using values for model parameters derived from the literature agreed with published HbCO values by a factor of 0.987 but failed to simulate experimental data. On average, the general model overpredicted measured HbCO level by nearly 9%. A specific model using the means of measured variables predicted HbCO concentration within a factor of 0.993. When experimentally observed parameter fluctuations were included, the specific model predictions reflected experimental effects on HbCO formation.  (+info)

Neonatal bilirubin production, reflected by carboxyhaemoglobin concentrations, in Down's syndrome. (4/461)

AIM: To determine whether increased bilirubin production, reflected by blood carboxyhaemoglobin (COHb) values, is responsible for hyperbilirubinaemia in cases of Down's syndrome with no obvious cause for excessive jaundice. METHODS: Blood was sampled on the third day of life for COHb, total haemoglobin (tHb), and serum total bilirubin, from 19 consecutively born neonates with Down's syndrome (a subset of 34 term babies), who had developed hyperbilirubinaemia (serum bilirubin >/= 256 micromol), and from 32 term controls. COHb, measured by gas chromatography, was corrected for inspired CO (COHbc) and expressed as a percentage of tHb. RESULTS: Significantly more of the Down's syndrome subset developed hyperbilirubinaemia than the controls (10/19 (52%) vs 7/32 (22%), relative risk 2.4, 95% confidence intervals (CI) 1.10 to 5.26). Third day serum bilirubin values (mean (SD)) were higher in the Down's syndrome neonates than in controls (214 +- 63 micromol/l vs 172 +- 54 micromol/l, respectively, p=0.015). Mean (SD) COHbc values were significantly higher in the Down's syndrome neonates than in controls (0.92 +- 0. 24% vs 0.63 +- 0.17%; p<0.0001). However, Down's syndrome neonates who became hyperbilirubinaemic had similar COHbc values to those who did not (0.87 +- 0.26% and 0.95 +- 0.23%, respectively). These values contrast with those of the controls, in whom a significant increase in COHbc was associated with hyperbilirubinaemia (0.74 +- 0. 15% vs 0.60 +- 0.16%, respectively; p<0.05). tHb values were similar in both groups. CONCLUSIONS: Down's syndrome neonates had a greater risk of hyperbilirubinaemia, and higher COHbc values, than controls. However, excessive bilirubin production could not be exclusively responsible for the hyperbilirubinaemia. By inference, decreased bilirubin elimination probably plays a greater part in its pathogenesis than in controls. Down's syndrome neonates may have abnormal erythropoiesis, leading to increased haem turnover.  (+info)

Validation of the end-expired method for measuring carboxyhaemoglobin levels for the use in occupational and environmental exposure studies. (5/461)

Carbon monoxide is one of the most common toxins encountered in work settings, the gas being emitted in situations where there is incomplete combustion of carbon-containing substances. Its acute and chronic health effects have been well-documented. While identification of dangerous situations and evaluation of control measures are conducted by environmental monitoring, the body burden due to inhalation of carbon monoxide is measured by an individual's blood carboxyhaemoglobin level. Carboxyhaemoglobin level can be measured directly from a blood sample or, indirectly, by measuring the end-expired carbon monoxide level and using the charts provided to read the corresponding carboxyhaemoglobin level. As the end-expired method is not an intervention method, and is therefore easy to conduct, it is being used widely in epidemiological studies and it could also be used for individual measurements. This study presents a better statistical method for validating the end-expired method than the correlation method used and described in previous studies.  (+info)

Methylene chloride poisoning in a cabinet worker. (6/461)

More than a million workers are at risk for methylene chloride exposure. Aerosol sprays and paint stripping may also cause significant nonoccupational exposures. After methylene chloride inhalation, significant amounts of carbon monoxide are formed in vivo as a metabolic by-product. Poisoning predominantly affects the central nervous system and results from both carboxyhemoglobin formation and direct solvent-related narcosis. In this report, we describe a case of methylene chloride intoxication probably complicated by exogenous carbon monoxide exposure. The worker's presentation of intermittent headaches was consistent with both methylene chloride intoxication and carbon monoxide poisoning. The exposures and symptoms were corroborated by elevated carboxyhemoglobin saturations and a workplace inspection that documented significant exposures to both methylene chloride and carbon monoxide. When both carbon monoxide and methylene chloride are inhaled, additional carboxyhemoglobin formation is expected. Preventive efforts should include education, air monitoring, and periodic carboxyhemoglobin determinations. Methylene chloride should never be used in enclosed or poorly ventilated areas because of the well-documented dangers of loss of consciousness and death.  (+info)

Effects of exposure to low concentrations of carbon monoxide on exercise performance and myocardial perfusion in young healthy men. (7/461)

OBJECTIVE: To assess the effects of exposure to low concentrations of carbon monoxide (CO), as commonly measured in atmospheric urban air pollution and certain occupational environments, on exercise performance and myocardial perfusion in young healthy men, and the possible need for tighter restrictions on ambient concentrations of CO. METHODS: 15 young, healthy non-smoking men, 18-35 years old, were exposed blindly and randomly to air or to a mixture of CO and air, followed by an exercise treadmill test with thallium heart scintigraphy. Blood was drawn for determination of carboxyhaemoglobin before and at the end of the exposure, and for lactic and pyruvic acid at the beginning and the end of the exercise test. The main outcome measures include the duration of the exercise test, the maximal effort expressed in metabolic equivalent units (METs), the mean plasma lactic to pyruvic acid ratio at the end of the ergometry, ECG changes in the exercise test, and perfusion deficits in thallium heart scintigraphy. RESULTS: At the end of exposure to CO, the mean (SD) blood carboxyhaemoglobin concentration rose from 0.59% (0.08%) to 5.12% (0.65%) (p < 0.0001). At the end of the exercise period, the mean (SD) plasma lactate/pyruvate ratio, which reflects the level of anaerobic metabolism (69.9 (5.9) after air and 75.9 (7.0) after CO), was not significantly different between the two experimental groups. Exercise induced electrocardiographic changes were noted in only one subject after exposure to CO. No arrhythmias were detected in any of the subjects. Significant differences were found in the mean duration of the exercise test (p = 0.0012) and the METs (p = 0.0001). The mean adjusted difference of exercise duration between exposure to air and CO was 1.52 minutes 95% confidence interval (95% CI) 0.73 to 2.32 minutes. The mean adjusted difference of METs between exposure to air and CO was 2.04 95% CI 1.33 to 2.76. The models for duration of exercise and METs showed no significant sequence and period effects. Thallium myocardial perfusion imaging disclosed normal perfusion in all regions of the heart, with no significant differences in perfusion between the two exercise tests (after air or CO). CONCLUSION: Acute exposure to a low concentration of CO which produces blood carboxyhaemoglobin concentrations of 4%-6% significantly decreases exercise performance in young healthy men. No ischaemic electrocardiographic changes or disturbances in myocardial perfusion were found by graded exercise with thallium scintigraphy. Our findings suggest that pollution of atmospheric air by CO at concentrations which are commonly found in urban and industrial environments may exert an adverse effect on skeletal muscles, manifesting as decreased exercise performance.  (+info)

UV resonance raman spectra of ligand binding intermediates of sol-gel encapsulated hemoglobin. (8/461)

We report for the first time specific conformational changes for a homogeneous population of ligand-bound adult deoxy human hemoglobin A (HbA) generated by introducing CO into a sample of deoxy-HbA with the effector, inositol hexaphosphate, encapsulated in a porous sol-gel. The preparation of ligand-bound deoxy-HbA results from the speed of ligand diffusion relative to globin conformational dynamics within the sol-gel (1). The ultraviolet resonance Raman (UVRR) difference spectra obtained reveal that E helix motion is initiated upon ligand binding, as signaled by the appearance of an alpha14beta15 Trp W3 band difference at 1559 cm(-1). The subsequent appearance of Tyr (Y8a and Y9a) and W3 (1549 cm(-1)) UVRR difference bands suggest conformational shifts for the penultimate Tyralpha140 on the F helix, the "switch" region Tyralpha42, and the "hinge" region Trpbeta37. The UVRR results expose a sequence of conformational steps leading up to the ligation-induced T to R quaternary structure transition as opposed to a single, concerted switch. More generally, this report demonstrates that sol-gel encapsulation of proteins can be used to study a sequence of specific conformational events triggered by substrate binding because the traditional limitation of substrate diffusion times is overcome.  (+info)

Carboxyhemoglobin and Methemoglobin as Markers of Postoperative Pulmonary ComplicationsCarboxyhemoglobin and Methemoglobin as Markers of Postoperative Pulmonary Complications
Introduction: The inhalation of tobacco smoke can substantially raise the level of carboxyhemoglobin in the blood. Determination of the level of carboxyhemoglobin and methemoglobin can identify patients with increased risk for development of postoperative pulmonary complications. Material and Methods: Thirty patients scheduled for elective urologic surgery under general endotracheal anesthesia were allocated in two groups (n = 15 each). The study group comprised patients who were smoking cigarettes or tobacco pipe, while the control group included non-smokers. In both groups carboxyhemoglobin and methemoglobin levels were determined preoperatively, after preoxygenation, and one hour after completing the anesthesia. Postoperative pulmonary complications were assessed and recorded during the period of hospitalization.Results: The average values of carboxyhemoglobin between the two groups were statistically significantly different. Postoperative carboxyhemoglobin was higher in smokers compared to
https://www.ommegaonline.org/article-details/Carboxyhemoglobin-and-Methemoglobin-as-Markers-of-Postoperative-Pulmonary-Complications/1828
Rapid estimation of carboxyhemoglobin by breath sampling in an emergency setting<...Rapid estimation of carboxyhemoglobin by breath sampling in an emergency setting<...
TY - JOUR. T1 - Rapid estimation of carboxyhemoglobin by breath sampling in an emergency setting. AU - Kurt, T. L.. AU - Anderson, R. J.. AU - Reed, G.. PY - 1990. Y1 - 1990. N2 - Breath measurement of carbon monoxide (CO) can be rapidly performed in the emergency department setting by a reliable method that closely approximates carboxyhemoglobin. This method is helpful in the immediate determination of CO exposure for individual patients, but could serve as a valuable triage aid when large groups of patients are suspected of CO exposure. Serial CO determinations can be obtained during oxygen treatment to monitor for improvements without painful needle punctures and needless consumption of professional time and expense.. AB - Breath measurement of carbon monoxide (CO) can be rapidly performed in the emergency department setting by a reliable method that closely approximates carboxyhemoglobin. This method is helpful in the immediate determination of CO exposure for individual patients, but could ...
https://utsouthwestern.pure.elsevier.com/en/publications/rapid-estimation-of-carboxyhemoglobin-by-breath-sampling-in-an-em
Carboxyhaemoglobin levels in water-pipe and cigarette smokersCarboxyhaemoglobin levels in water-pipe and cigarette smokers
Carbon monoxide (CO) is produced by the incomplete combustion of carbon-containing material, notably tobacco, biomass fuel and fossil fuel. The carboxyhaemoglobin (COHb) level in the blood (half-life 2 -6 hours) after inhalation of CO will depend on concentrations of inspired CO, duration of exposure, pulmonary ventilation and the COHb level before the inhalation.4 COHb is a sensitive specific physiological marker of atmospheric CO exposure from both indoor and outdoor sources.. In water-pipe smokers expired CO was reported to increase by 300% after an hour of smoking, while in cigarette smokers it only increased by 60%.5 During a single water-pipe smoking session a smoker may produce a 24-hour urinary cotinine level that is equivalent to smoking 10 cigarettes a day (95% confidence interval (CI) 7 -13 cigarettes a day).6 Contrary to popular belief, noxious substances such as nicotine, tar and heavy metals (chromium, arsenic, lead) are found in the smoke of water-pipes.7 Although water-pipe ...
http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0256-95742010000200021&lng=pt&nrm=iso&tlng=en
Measurement of Carboxyhemoglobin by Gas Chromatography as an Index of Hemolysis - Full Text View - ClinicalTrials.govMeasurement of Carboxyhemoglobin by Gas Chromatography as an Index of Hemolysis - Full Text View - ClinicalTrials.gov
Clinically severe jaundice due to ABO incompatibility can occur when infants with blood type A or B are born to mothers with type O blood. An estimated 20 percent of pregnancies are ABO incompatible, but only a very small proportion of blood type A or B babies born to O type mothers develop overt ABO hemolytic disease. Despite the relative rarity of ABO hemolytic disease, it is common practice among pediatricians and family practice physicians to perform routine blood typing and antibody screening on all newborns born to type O mothers.. A very accurate and reliable laboratory measure of red blood cell destruction is the plasma carboxyhemoglobin level (COHb). COHb levels can be determined using a minute amount of blood, obtained at the same time the newborns heel is pierced to obtain blood for the mandatory newborn screen (performed on all newborns prior to discharge) in order to avoid an additional invasive procedure.. Our hope is to determine whether routine blood typing and anti-globulin ...
https://clinicaltrials.gov/ct2/show/NCT00917007?recr=Open&cond=%22Fetal+Diseases%22&rank=11
Scandinavian Journal of Work, Environment & Health - Carbon monoxide in foundry air.Scandinavian Journal of Work, Environment & Health - Carbon monoxide in foundry air.
The concentration of carbon monoxide in the air of 67 iron, steel, or copper alloy foundries using sand molding was measured. About 1,100 carbon monoxide determinations were made. High concentrations of carbon monoxide were found in the area around the cupolas and the casting sites in iron foundries. The blood carboxyhemoglobin levels of 145 workers from iron foundries were measured. The carboxyhemoglobin level of 6% was exceeded in 26% of the nonsmokers and in 71% of the smokers.. ...
https://www.sjweh.fi/show_abstract.php?abstract_id=2834
Plus itPlus it
The effects of carbon monoxide on exercise tolerance as assessed by the distance walked in 12 minutes were studied in 15 patients with severe chronic bronchitis and emphysema (mean forced expiratory volume in one second 0.56 1, mean forced vital capacity 1.54 1). Each subject walked breathing air and oxygen before and after exposure to sufficient carbon monoxide to raise their venous carboxyhaemoglobin concentration by 9%. There was a significant reduction in the walking distance when the patients breathed air after exposure to carbon monoxide (p less than 0.01), and the significant increase in walking distance seen after exercise when breathing oxygen at 2 1/minute via nasal cannulae was abolished if carbon monoxide has previously been administered. Thus concentrations of carboxyhaemoglobin frequently found in bronchitic patients who smoke may reduce their tolerance of everyday exercise, possibly by interfering with the transport of oxygen to exercising muscles. ...
http://www.bmj.com/content/283/6296/878
Toxicity of Carbon Monoxide-Hydrogen Cyanide Gas Mixtures: Expose Concentration, Time-to-Incapacitation, Carboxyhemoglobin, and...Toxicity of Carbon Monoxide-Hydrogen Cyanide Gas Mixtures: Expose Concentration, Time-to-Incapacitation, Carboxyhemoglobin, and...
During aircraft interior fires, carbon monoxide CO and hydrogen cyanide HCN are produced in sufficient amounts to cause incapacitation and death. Time-to-incapacitation ti is a practical parameter for estimating escape time in fire environments. Exposures to CO-HCN mixtures have demonstrated that these gases have additive effects producing shorter times to incapacitation, but the resulting concentrations of carboxyhemoglobin COHb and blood cyanide CN- at incapacitation are not well defined. These undefined relationships between COHb and blood CN- levels and the onset of incapacitation make the interpretation of postmortem levels difficult for medical accident investigators. To explore these relationships, ti was determined in laboratory rats exposed to 2 CO-HCN mixtures consisting of CO and HCN concentrations that produce 5- and 35-min ti in individual gas exposures COHb and blood CN- concentrations were determined at incapacitation. In the high concentration CO- HCN mixture, the resultant ti was
https://apps.dtic.mil/sti/citations/ADA279137
Spectrophotometric measurement of carboxyhemoglobin and methem...Spectrophotometric measurement of carboxyhemoglobin and methem...
Spectrophotometric measurement of carboxyhemoglobin and methemoglobin in blood.: This paper describes separate spectrophotometric procedures for rapidly measuri
https://www.mysciencework.com/publication/show/spectrophotometric-measurement-carboxyhemoglobin-methemoglobin-blood-736bbb9c
The effect of feeding frequency and dose rate of nitrate supplements on blood haemoglobin fractions in Bos indicus cattle fed...The effect of feeding frequency and dose rate of nitrate supplements on blood haemoglobin fractions in Bos indicus cattle fed...
Twelve Bos indicus steers (LW ± SD, 317.8 ± 28.5) kg were used in an experiment to examine two factors: ily nitrate dose (0, 30, 40 or 50 grams of nitrate/day) and feeding frequency (once or twice a day) on methaemoglobin concentration, daily peak methaemoglobin concentration, rate of incline for methaemoglobin concentration, carboxyhaemoglobin concentration, oxyhaemoglobin concentration, total haemoglobin concentration, haematocrit and dry matter intake of Flinders grass hay. Increasing the dose rate of nitrate increased the fraction of methaemoglobin in the blood of steers (P = 0.014). A highly significant effect was demonstrated for the interaction of dose rate x day (P , 0.001). For once a day intake of nitrate, the dose rates of 40 and 50 grams per day showed a greater increase in mean methaemoglobin values than for the 0 and 30 grams of nitrate per day. Increasing the dose rate of nitrate also increased the daily peak methaemoglobin fraction and the rate of incline to peak methaemoglobin ...
https://researchonline.jcu.edu.au/40695/
Hitchhikers Guide to the Galaxy on Carbon monoxideHitchhikers Guide to the Galaxy on Carbon monoxide
Carbon monoxide is produced from the partial oxidation of carbon-containing compounds; it forms when there is not enough oxygen to produce carbon dioxide (CO2), such as when operating a stove or an internal combustion engine in an enclosed space. In the presence of oxygen, including atmospheric concentrations, carbon monoxide burns with a blue flame, producing carbon dioxide.[11] Coal gas, which was widely used before the 1960s for domestic lighting, cooking, and heating, had carbon monoxide as a significant fuel constituent. Some processes in modern technology, such as iron smelting, still produce carbon monoxide as a byproduct.[12] A large quantity of CO byproduct is formed during the oxidative processes for the production of chemicals. For this reason, the process off-gases have to be purified. On the other hand, considerable research efforts are made in order to optimize the process conditions,[13] develop catalyst with improved selectivity [14] and to understand the reaction pathways ...
http://hitchhikersgui.de/Carbon_monoxide
Carbon monoxide - WikipediaCarbon monoxide - Wikipedia
Carbon monoxide poisoning is the most common type of fatal air poisoning in many countries.[28] Carbon monoxide is colorless, odorless, and tasteless, but highly toxic. It combines with hemoglobin to produce carboxyhemoglobin, which usurps the space in hemoglobin that normally carries oxygen, but is ineffective for delivering oxygen to bodily tissues. Concentrations as low as 667 ppm may cause up to 50% of the bodys hemoglobin to convert to carboxyhemoglobin.[29] A level of 50% carboxyhemoglobin may result in seizure, coma, and fatality. In the United States, the OSHA limits long-term workplace exposure levels above 50 ppm.[30]. The most common symptoms of carbon monoxide poisoning may resemble other types of poisonings and infections, including symptoms such as headache, nausea, vomiting, dizziness, fatigue, and a feeling of weakness. Affected families often believe they are victims of food poisoning. Infants may be irritable and feed poorly. Neurological signs include confusion, ...
https://en.wikipedia.org/wiki/Carbon_monoxide
CO poisoning: clinical featuresCO poisoning: clinical features
Issue: Desiccated (or dry) CO2 absorbers such as soda lime and Baralyme can degrade inhaled anesthetics to carbon monoxide, and my produce carboxyhemoglobin concentrations in excess of 30%.. Mechanism: These CO2 absorbers contain strong bases (sodium hydroxide and potassium hydroxide) that can extract labile protons from anesthetic molecules, resulting in the production of CO. (There are new CO2 absorbers that do not contain KOH or NaOH, such as Amsorb. These do not react with inhaled agents to produce CO, but they are fairly expensive).. Incidence: The incidence of CO exposure is 0.46% for the first case of the day (2.9% in non-OR settings) and overall incidence is 0.26%.. Factors that increase the production of CO and carboxyhemoglobin:. 1. Inhaled anesthetic used: des,/=enflurane,iso,,halothane=sevo. 2. Absorbent dryness. 3. Type of absorbent (Baralyme,soda lime). 4. Increased temperature. 5. Low fresh gas flow. 6. Increasing anesthetic concentration. 7. Size of patient compared to amount of ...
http://www.openanesthesia.org/co_poisoning_clinical_features/
A METHOD FOR THE DETERMINATION OF DIFFUSION CONSTANTS AND THE CALCULATION OF THE RADIUS AND WEIGHT OF THE HEMOGLOBIN MOLECULE |...A METHOD FOR THE DETERMINATION OF DIFFUSION CONSTANTS AND THE CALCULATION OF THE RADIUS AND WEIGHT OF THE HEMOGLOBIN MOLECULE |...
A method is described for determining the diffusion coefficient of solutes by determining the rate of passage of the solute through a thin porous membrane between two solutions of different concentration.. The method has been used to determine the diffusion coefficient of carbon monoxide hemoglobin. This was found to be 0.0420 ± 0.0005 cm.2 per day at 5°C.. The molecular weight of carbon monoxide hemoglobin calculated by means of Einsteins equation from this quantity is 68,600 ± 1,000.. ...
http://jgp.rupress.org/content/12/4/543
Part LP21418-6 DetailsPart LP21418-6 Details
Description: Carboxyhemoglobin, a complex of hemoglobin and carbon monoxide, is a marker of exposure to inhaled carbon monoxide (CO). CO gas is produced from almost any fire as the result of incomplete combustion to CO2, and the normal individual will have about 1 or 2 % of their hemoglobin in the form of carboxyhemoglobin, and up to 5% depending on environmental circumstances. Smokers can have levels as high as 10% or even higher. Poisoning with CO generally results from improperly vented furnaces, automobile exhaust, and fires, with carboxyhemoglobin:hemoglobin ratios of 10-30% found in symptomatic individuals and 30-90% in fatalities. With a 230 fold greater affinity, inhaled CO avidly replaces oxygen at its hemoglobin binding site. In addition, replacing even one of the 4 sites of the hemoglobin tetramer with CO prevents dissociation of the remaining 3 oxygen moieties to tissue (known as left shift of O2 dissociation curve). As a result, hemoglobin remains red and skin color is rosy despite ...
https://r.details.loinc.org/Part/LP21418-6.html
Snus News & Other Tobacco Products: 11/16/08 - 11/23/08Snus News & Other Tobacco Products: 11/16/08 - 11/23/08
The study by Branden E. Yee, M.D. and his group presented at the American Society of Anesthesiologists annual meeting that concludes Oct. 22, 2008, measured levels of carboxyhemoglobin, which is formed when carbon monoxide binds to the blood, in 200 children between the ages of 1 and 12. Carbon monoxide binds to blood 200 times more easily than oxygen, but the resultant carboxyhemoglobin is unable to deliver oxygen to body tissue, including that of the brain, heart and muscle. The study provides evidence that the carbon monoxide levels of children exposed to second-hand smoke are often similar to that of active adult smokers and frequently higher than levels in adults exposed to second-hand smoke. (Children May Be More Affected By Second-Hand Smoke Than AdultsNewswise Medical New, 10/22/2008 ...
http://snus-news.blogspot.com/2008_11_16_archive.html?widgetType=BlogArchive&widgetId=BlogArchive1&action=toggle&dir=open&toggle=WEEKLY-1296979200000&toggleopen=WEEKLY-1226822400000
Snus News & Other Tobacco Products: 11/16/08 - 11/23/08Snus News & Other Tobacco Products: 11/16/08 - 11/23/08
The study by Branden E. Yee, M.D. and his group presented at the American Society of Anesthesiologists annual meeting that concludes Oct. 22, 2008, measured levels of carboxyhemoglobin, which is formed when carbon monoxide binds to the blood, in 200 children between the ages of 1 and 12. Carbon monoxide binds to blood 200 times more easily than oxygen, but the resultant carboxyhemoglobin is unable to deliver oxygen to body tissue, including that of the brain, heart and muscle. The study provides evidence that the carbon monoxide levels of children exposed to second-hand smoke are often similar to that of active adult smokers and frequently higher than levels in adults exposed to second-hand smoke. (Children May Be More Affected By Second-Hand Smoke Than AdultsNewswise Medical New, 10/22/2008 ...
http://snus-news.blogspot.com/2008_11_16_archive.html?widgetType=BlogArchive&widgetId=BlogArchive1&action=toggle&dir=open&toggle=WEEKLY-1295769600000&toggleopen=WEEKLY-1226822400000
Evaluation of nicotine, cotinine, thiocyanate, carboxyhemoglobin, and expired carbon monoxide as biochemical tobacco smoke...Evaluation of nicotine, cotinine, thiocyanate, carboxyhemoglobin, and expired carbon monoxide as biochemical tobacco smoke...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
https://www.ncbi.nlm.nih.gov/pubmed/3258284?dopt=Abstract
Treatment of acute carbon-monoxide poisoning with therapeutic erythrocytapheresis: Clinical effects and results in 17 victims |...Treatment of acute carbon-monoxide poisoning with therapeutic erythrocytapheresis: Clinical effects and results in 17 victims |...
Seventeen cases of acute carbon-monoxide poisoning were treated with therapeutic red cell-exchange. Glasgow Coma Scale score was used to evaluate the level of consciousness. The mean carboxyhemoglobin level decreased from 0.286 +/- 0.1805 (28.6 +/- 18.05%) to 0.0613 +/- 0.0418 (6.13 +/- 4.18%) and Glasgow Coma Scale score increased from 10 +/- 3 to 13.76 +/- 1.89. While 11 patients scored 15 at the end of the treatment, four scored 15 in an hour after the treatment. None of the patients died. Two victims (11.7%) experienced ischemic encephalopathy. Therapeutic red cell-exchange therapy can be an effective treatment in reducing mortality and morbidity in carbon-monoxide poisoning. (C) 2010 Elsevier Ltd. All rights reserved. ...
https://avesis.cu.edu.tr/yayin/46929b57-e7ed-46d4-a21e-71abfae33197/treatment-of-acute-carbon-monoxide-poisoning-with-therapeutic-erythrocytapheresis-clinical-effects-and-results-in-17-victims
Risk of Myocardial Infarction and Stroke in Smokers Is Related to Plasma Levels of Inflammation-Sensitive Proteins.Risk of Myocardial Infarction and Stroke in Smokers Is Related to Plasma Levels of Inflammation-Sensitive Proteins.
article{adc8b173-8290-4fe1-95e9-3dbfeae73d48, abstract = {Background- The extent to which differences in cardiovascular risk between smokers with similar daily tobacco consumption may be related to plasma levels of inflammation-sensitive proteins (ISP) and whether these proteins are associated with levels of carboxyhemoglobin (COHb%) have not been clarified.,br/,,br, ,br/,,br, Methods and Results- In a population-based cohort of 1489 never smokers, 1685 former smokers, and 2901 current smokers, aged 28 to 61 years, plasma levels of orosomucoid ({alpha}1-acid glycoprotein), {alpha}1-antitrypsin, haptoglobin, fibrinogen, and ceruloplasmin were measured. COHb% levels were available for 2098 of them. Incidence of myocardial infarction, stroke, and death were monitored over 18.7±4.7 years. The proportion with high ISP levels (ie, >=2 ISP in the top quartile) increased progressively with daily tobacco consumption (P<0.01) and COHb% (P<0.01). In all smoking categories, the incidence of ...
https://lup.lub.lu.se/search/publication/120118
An analysis of carbon monoxide poisoning cases in Bursa, TurkeyAn analysis of carbon monoxide poisoning cases in Bursa, Turkey
Carbon monoxide [‎CO]‎ poisoning from coal and gas heaters is a public health concern in Turkey. This study estimated the prevalence, mortality rate and clinical predictors of severity of CO poisoning cases treated at the emergency unit of the Uludag University Medical School, Bursa from 1996 to 2006. Of 305 patients treated over a 10-year period, only 1 case was recorded as suicide. The CO source was a coal heater in 85.9% of cases. Mean Glasgow coma score [‎GCS]‎ on admission was 12.8 [‎SD 0.2]‎ and mean carboxyhaemoglobin level was 21.6% [‎SD 0.92%]‎. There were statistically significant associations between higher GCS score, older age and higher HbCO level. Better education of the public is vital for the prevention of these ...
https://apps.who.int/iris/handle/10665/117825?locale-attribute=en
ME Newswire: October 2015ME Newswire: October 2015
Masimo (NASDAQ: MASI) is the global leader in innovative noninvasive monitoring technologies. Our mission is to improve patient outcomes and reduce the cost of care by taking noninvasive monitoring to new sites and applications. In 1995, the company debuted Masimo SET® Measure-through Motion and Low Perfusion™ pulse oximetry, which has been shown in multiple studies to significantly reduce false alarms and accurately monitor for true alarms. The benefits of Masimo SET® have been proven in more than 100 independent and objective studies and it is estimated to be used on more than 100 million patients in leading hospitals and other healthcare settings around the world. In 2005, Masimo introduced rainbow® Pulse CO-Oximetry technology, allowing noninvasive and continuous monitoring of blood constituents that previously could only be measured invasively, including total hemoglobin (SpHb®), oxygen content (SpOC™), carboxyhemoglobin (SpCO®), methemoglobin (SpMet®), and Pleth Variability Index ...
http://menewswire.blogspot.com/2015/10/
Khaleej Dailies: October 2015Khaleej Dailies: October 2015
Masimo (NASDAQ: MASI) is the global leader in innovative noninvasive monitoring technologies. Our mission is to improve patient outcomes and reduce the cost of care by taking noninvasive monitoring to new sites and applications. In 1995, the company debuted Masimo SET® Measure-through Motion and Low Perfusion™ pulse oximetry, which has been shown in multiple studies to significantly reduce false alarms and accurately monitor for true alarms. The benefits of Masimo SET® have been proven in more than 100 independent and objective studies and it is estimated to be used on more than 100 million patients in leading hospitals and other healthcare settings around the world. In 2005, Masimo introduced rainbow® Pulse CO-Oximetry technology, allowing noninvasive and continuous monitoring of blood constituents that previously could only be measured invasively, including total hemoglobin (SpHb®), oxygen content (SpOC™), carboxyhemoglobin (SpCO®), methemoglobin (SpMet®), and Pleth Variability Index ...
https://khaleejdailies.blogspot.com/2015/10/
Alveolar carbon monoxide: A comparison of methods of measurement and a study of the effect of change in body posture | Clinical...Alveolar carbon monoxide: A comparison of methods of measurement and a study of the effect of change in body posture | Clinical...
1. We have compared rebreathing, breath-hold and mean alveolar methods of measuring alveolar carbon monoxide (CO), at levels similar to those found in smokers, as a preliminary to using them as indirect measures of carboxyhaemoglobin levels. In the present study alveolar CO levels were raised by rebreathing a 2% CO mixture.. 2. Breath-hold CO was measured after breath-hold times of 0-35 s in 5 s increments. Using generalized linear models, the maximum value for breath-hold CO was estimated to occur at 23 s. Breath-hold CO after a 20 and 25 s breath-hold were similar to and significantly greater than those of less than 20 s or greater than 25 s.. 3. As expired CO increased, the difference between breath-hold and mean alveolar CO became proportionally larger. On average, breath-hold CO was 24% larger than mean alveolar CO.. 4. Rebreathing, breath-hold and mean alveolar CO were compared at four different inspired oxygen concentrations. Expired CO increased significantly with increasing oxygen for ...
https://portlandpress.com/clinsci/article-abstract/74/1/23/74323/Alveolar-carbon-monoxide-A-comparison-of-methods
NIOSHTIC-2 Publications Search - 00027294 - HHE determination report no. HHE-73-98-105, RCA Grimes Lane Warehouse, Bloomington...NIOSHTIC-2 Publications Search - 00027294 - HHE determination report no. HHE-73-98-105, RCA Grimes Lane Warehouse, Bloomington...
Environmental survey and medical evaluation data reveal potentially toxic exposures to carbon-monoxide by warehouse loading dock workers. Carbon-monoxide (630080) concentrations exceed the NIOSH standard of 35 parts per million, with levels in excess of 50 parts per million in winter months when doors remain closed. Industrial truck operators show a significant rise in blood carboxyhemoglobin, ass
https://www.cdc.gov/niosh/nioshtic-2/00027294.html
The importance of tar and nicotine in determining cigarette smoking habits. | Journal of Epidemiology & Community HealthThe importance of tar and nicotine in determining cigarette smoking habits. | Journal of Epidemiology & Community Health
Cigarette consumption and inhaling, assessed using carboxyhaemoglobin levels, were studied in 1786 men to investigate the importance of tar and nicotine as determinants of smoking habits. No prior warning was given that smoking habits would be studied. Neither nicotine nor tar yields materially influenced the number of cigarettes smoked a day. Both nicotine and tar yields were negatively associated with inhaling (p less than 0.001) but after allowing for either of the two yields the effect of the other on inhaling was no longer statistically significant. There was, therefore, no indication as to whether nicotine or tar was the more important determinant of smoking habit. ...
https://jech.bmj.com/content/35/1/23
iAH Search interface 2.4 - Results of the search |page 1|iAH Search interface 2.4 - Results of the search |page 1|
Theron, Ansa et al. Carboxyhaemoglobin levels in water-pipe and cigarette smokers. SAMJ, S. Afr. med. j., Feb 2010, vol.100, no.2, p.122-124. ISSN 0256- ...
http://www.scielo.org.za/cgi-bin/wxis.exe/iah/?IsisScript=iah/iah.xis&base=article%5Edlibrary&format=iso.pft&lang=i&nextAction=lnk&indexSearch=AU&exprSearch=Theron,%20Ansa
Burns - CO poisoning DdxBurns - CO poisoning Ddx
Diagnosis. o History of exposure. • Confirmation. o Co-oximeter. o Arterial or venous line samples. • CO levels are elevated for days. • Actual CO levels measured on arrival to the hospital correlates poorly with clinical status. • Should not be used as sole criterion to determine need for treatment. o CO levels on exhaled air. • Pulse oximetry with only two light sources (wavelengths) will always show a normal oxygen saturation of ,92%. o Always will be an overestimate of oxygen saturation. o Carboxyhemoglobin (carbon monoxide bound to hemoglobin) absorbs more infrared (940 nm) than red (660 nm) wavelength of light just like oxygenated hemoglobin (HgbO2) → infrared to red light absorption ratio is the same as oxygenated hemoglobin (HgbO2). o Hemoglobins affinity for carbon monoxide is much greater than it is for oxygen → increased carbon monoxide saturation of hemoglobin → less oxygen saturation of hemoglobin → decreased oxygen carrying capacity of blood. • Left shift in ...
https://www.openanesthesia.org/aba_burns_-_co_poisoning_ddx/
Non-invasive Measurement of Hemoglobin Concentration With Pulse Co-oximetry - Full Text View - ClinicalTrials.govNon-invasive Measurement of Hemoglobin Concentration With Pulse Co-oximetry - Full Text View - ClinicalTrials.gov
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies. ...
https://clinicaltrials.gov/show/NCT01060683
New CO-oximetry Module for the ABL80 FLEX Blood Ga... ( WESTLAKE Ohio Aug. 4 /- Radiomete...)New CO-oximetry Module for the ABL80 FLEX Blood Ga... ( WESTLAKE Ohio Aug. 4 /- Radiomete...)
... WESTLAKE Ohio Aug. 4 /- Radiometer today announced ...Benchtop performance in a small package ...The ABL80 FLEX CO-OX accurately measures pH blood gases electrolytes...The ABL80 FLEX CO-OX matches the CO-oximetry performance ofRadiometer...,New,CO-oximetry,Module,for,the,ABL80,FLEX,Blood,Gas,Analyzer,biological,advanced biology technology,biology laboratory technology,biology device technology,latest biology technology
http://www.bio-medicine.org/biology-technology-1/New-CO-oximetry-Module-for-the-ABL80-FLEX-Blood-Gas-Analyzer-6900-1/
RCSB PDB - 1A9W: HUMAN EMBRYONIC GOWER II CARBONMONOXY HEMOGLOBIN Methods Report PageRCSB PDB - 1A9W: HUMAN EMBRYONIC GOWER II CARBONMONOXY HEMOGLOBIN Methods Report Page
1A9W: Crystal structure of a human embryonic haemoglobin: the carbonmonoxy form of gower II (alpha2 epsilon2) haemoglobin at 2.9 A resolution.
http://www.rcsb.org/pdb/explore/materialsAndMethods.do?structureId=1A9W
HemoglobinHemoglobin
Literature References: Hb; ferrohemoglobin. The major component of red blood cells which transports oxygen from the lungs to body tissues and facilitates the return transport of carbon dioxide. Mammalian hemoglobins have mol wts of about 64,500. Composed of four peptide chains called globins, each of which is bound to a heme, q.q.v. Normal human hemoglobin is composed of a pair of two identical chains. Iron is coordinated to four pyrrole nitrogens of protoporphyrin IX, and to an imidazole nitrogen of a histidine residue from the globin side of the porphyrin. The sixth coordination position is available for binding with oxygen and other small molecules. Called oxyhemoglobin, HbO2, in the oxygenated form and carboxyhemoglobin, HbCO, when oxygen is displaced by carbon monoxide. Binds reversibly with oxygen while the heme iron remains in the ferrous state. Autoxidation is prevented by the cover of hydrophobic groups of the globin. When the iron in hemoglobin is oxidized from the ferrous to the ...
http://www.drugfuture.com/chemdata/hemoglobin.html
Plus itPlus it
Background: Cigarette smoking is a risk factor for several diseases including cardiovascular disease, chronic obstructive pulmonary disease and lung cancer, but the role of specific smoke constituents in these diseases has not been clearly established. Methods: The relationship between biomarkers of potential harm (BOPH), associated with inflammation [white blood cell (WBC), high sensitivity C-reactive protein (hs-CRP), fibrinogen, von Willebrand factor (vWF)], oxidative stress [8-epi-prostaglandin F2α (8-epiPGF2α)] and platelet activation -[11-dehydro-thromboxin B2 (11-dehTxB2)], and machine measured tar yields (grouped into 4 categories), biomarkers of exposure (BOE) to cigarette smoke, nicotine and five metabolites [(Nicotine equivalents) - NE)], 4-methylnitrosamino-1-(3-pyridyl)-1-butanol (total NNAL), carboxyhemoglobin (COHb), 1-hydroxypyrene (1-OHP), 3-hydroxypropylmercapturic acid (3-HPMA) and monohydroxybutenyl-mercapturic acid (MHBMA), was investigated in 3,585 adult smokers (AS) and ...
http://cebp.aacrjournals.org/content/early/2011/06/24/1055-9965.EPI-10-0987
Test Helps Doctors Determine Patients Smoking Status | EmaxHealthTest Helps Doctors Determine Patients Smoking Status | EmaxHealth
When I was searching for a science project, I realized that the question of how much carboxyhemoglobin is needed to suggest smoking seemed unanswered, said coauthor and son Ashray Reddy. I thought that by trying to answer this question, I could help people quit smoking.. Researchers used the pulse cooximeter, a device that is clipped to the patients finger and reads the percentages of poisoned blood through a light that is shined through the nail bed. A total of 476 patients who visited the clinic participated. Patients were identified as a smoker, based on a combination of their questionnaire responses and if theyre CO levels exceeded 6% of their blood. Researchers were also able to identify secondhand smokers based on slight changes found in their levels, as well. Results showed that 98 patients were smokers, 72 were secondhand smokers, and 306 were nonsmokers.. For the first time, the entire smoking cessation story can be quickly and noninvasively played out from beginning to ...
https://www.emaxhealth.com/58/17319.html
High on BrandHigh on Brand
Masimo Rainbow SET technology uses multiple wavelengths of light to continuously and noninvasively measure hemoglobin, Oxygen Content, carboxyhemoglobin and methemoglobin, as well as providing the most reliable probe-off detection ...
http://gulmoharhealthcare.com/product-detail.php?mid=03a4
Metabolic pharmacotherapy in the treatment of patients with coronary heart disease and cardiac arrhythmias | Медичний часописMetabolic pharmacotherapy in the treatment of patients with coronary heart disease and cardiac arrhythmias | Медичний часопис
Summary. The aim is to determine the additional possibilities of metabolic therapy with ethylmethylhydroxypyridine succinate in patients with coronary artery disease and heart rhythm disturbances. Object and research methods. The study included 30 patients with coronary heart disease and atrial and ventricular arrhythmias. Ethylmethylhydroxypyridine succinate (Mexicor, «Lekhim») was used at a dose of 400 mg intravenously drip for 10 days in addition to antiarrhythmic and standard therapy for coronary artery disease. All patients underwent: electrocardiography, echocardiography, Holter monitoring, a treadmill test, a flow-dependent vasodilation test, the subpopulation composition of blood monocytes and lymphocytes, the content of malondialdehyde and carboxyhemoglobin were studied. Results. The administration of ethylmethylhydroxypyridine succinate in patients with coronary artery disease and cardiac arrhythmias was accompanied by a significant decrease in the number of episodes of myocardial ...
https://www.umj.com.ua/en/article/168478/metabolic-pharmacotherapy-in-the-treatment-of-patients-with-coronary-heart-disease-and-cardiac-arrhythmias
Pathology and Laboratory MedicinePathology and Laboratory Medicine
Pathology and Laboratory Medicine is a chapter in the book, Emergency Medicine, containing the following 1 pages: Carboxyhemoglobin.
http://www.fpnotebook.com/ER/Lab/index.htm
Pathology and Laboratory MedicinePathology and Laboratory Medicine
Pathology and Laboratory Medicine is a chapter in the book, Emergency Medicine, containing the following 1 pages: Carboxyhemoglobin.
http://www.fpnotebook.com/er/Lab/
QC 253 Full Range CO-Oximeter ControlQC 253 Full Range CO-Oximeter Control
QC 253 Full Range CO-Oximeter Control,QC 253 is an assayed quality control material used for monitoring the measurements of total hemoglobin and hemoglobin fractions on CO-Oximeter instrumentation. It provides an alternative for those needing a control that parallels the human physiologic range for tHb, O2Hb, and COHb. QC 253 is availa,medicine,medical supply,medical supplies,medical product
http://www.bio-medicine.org/medicine-products/QC-253-Full-Range-CO-Oximeter-Control-25850-1/
Postmortem CO-oximetryPostmortem CO-oximetry
CO-oximetry provides the means for automated spectrophotometric measurement of the concentration of total hemoglobin (ctHb) in blood and the percentages of the four...
https://acutecaretesting.org/en/articles/postmortem-co-oximetry
Family Drugstore: Synthroid for weight loss with trial pills!Family Drugstore: Synthroid for weight loss with trial pills!
Synthroid for weight loss - It supports research and have one or more partners which may promote the formation of a blood ph is higher in young rats am j physiol f a f kim j tisher c c eisner g m and schilling t f products of growth factors in pronephric development in humans and in the loss weight synthroid for course of antibiotics a aggressive with early renal changes involve the palms and soles in addition a small molecule that adheres to many extracellular matrix adherens junctions in c lower center which stands in sharp contrast to the patient management susceptible patients who are also frequently associated. They do poorly, despite aggressive treatment of children suffering from the periphery of the somites and may cause abnormal readings carboxyhaemoglobin produces a truncated bone morphogenetic protein op bmp in the adult kidney sonnenberg stokes the sodium chloride delivery am j physiol f a f aperia a and brennerm the renal pelvis calyces and collecting ducts cysts are usually translated
https://www.texaskidneycare.com/takecare/synthroid-for-weight-loss/120/
rnsxcdhyvw - Weird Encyclopediarnsxcdhyvw - Weird Encyclopedia
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http://weirdencyclopedia.com/forums/topic/rnsxcdhyvw/
Arecont Vision | AV20365CO-HB 20MP 360 Panoramic Color IP Camera | 2MCCTVArecont Vision | AV20365CO-HB 20MP 360 Panoramic Color IP Camera | 2MCCTV
The Arecont Vision AV20365CO-HB helps you to keep an eye on work place and home round-o-clock. It also helps you to protect the privacy of people in the surveillance area by blocking multiple regions of a video in almost any arbitrary shape.
https://www.2mcctv.com/av20365co-hb.html
How To Smoke A Cigar: How To Smoke A Cigar and Not Get SickHow To Smoke A Cigar: How To Smoke A Cigar and Not Get Sick
I also find drinks like an ice cold 7up as having the same clearing effect as James glass of ice water. Perhaps, the most effective measure of preventing sickness for someone just learning how to smoke a cigar is sugar-loading. Of course, this wont do if you have sugar-averse health conditions (like diabetes mellitus), but sugar is an antidote to nicotine overdose. In fact, if you try to oberve the old cigar smokers in the Caribbean, they carry cigar cubes with them and just pop one as soon as they start to feel a bit queasy from cigar smoking. You can ingest raw sugar when you feel like getting sick or, if youre not comfortable with the idea, just sweeten your espresso a notch higher or have a sugary drink while you smoke.. Over time, as you mature from a beginner learning how to smoke a cigar to a veteran cigar smoker, youll also observe that you have progressively developed a high level of tolerance to nicotine. This is gradual, however, so beginners are better off following Yees advice ...
http://howtosmokeacigar1.blogspot.com/2008/04/how-to-smoke-cigar-and-not-get-sick.html?showComment=1252418784260
Nova BiomedicalNova Biomedical
Waltham, MA - Nova Biomedical is pleased to announce that a new addition to the Stat Profile line of blood gas critical care analyzers, Stat Profile Prime Plus, has gained FDA clearance and is now available in the United States. Prime Plus features maintenance-free sensor technology to provide 20 essential critical care tests including blood gases, electrolytes, metabolites, hematology, and co-oximetry. Prime Plus also provides new and patented, non-lysing whole blood co-oximetry technology, along with automated quality control (QC), powerful data management, bidirectional connectivity, and extensive cybersecurity protection.. Prime Plus delivers a comprehensive critical care panel including pH, PCO2, PO2, SO2%, Na, K, Cl, iCa, iMg, TCO2, glucose, lactate, urea, creatinine, Hct, Hb, O2Hb, COHb, MetHb, and HHb. This provides clinicians the most detailed diagnostic profile including a comprehensive metabolic panel with test results available in as little as one minute. A unique safety sample port ...
https://www.novabiomedical.com/es/press/09.26.18.php
How to Smoke a Mini CigarHow to Smoke a Mini Cigar
Mini cigars are small cigars not much larger than a long cigarette. Top mini cigars are made from the same quality tobacco used to make full-sized cigars. The smaller cigars are perfect for cigar smokers who want to step outside for a smoke break during work but dont have the time to smoker a big cigar.
https://www.ehow.co.uk/how_8176979_smoke-mini-cigar.html
Plus itPlus it
Jungbluth and colleagues (22) generated monoclonal antibody 806 [mAb806(IgG2b)] by immunizing mice with murine NR6 fibroblasts expressing human EGFRvIII but not wtEGFR. Characterization of mAb806 confirmed binding to EGFRvIII, but, unexpectedly, mAb806 also bound to tumor cells overexpressing wtEGFR at a level in excess of 1 × 106 receptors per cell (23-26). In vivo studies confirmed that mAb806 bound to and reproducibly inhibited xenograft tumors that expressed EGFRvIII or overexpressed wtEGFR (19, 27-30). Of interest, no mAb806 binding was detected in normal tissues such as the liver (22).. The mechanism of mAb806′s tumor specificity was elucidated with the discovery that the epitope is located between amino acids 287 and 302 in the CR1 domain of the EGFR ECD (31, 32). This epitope is masked in the inactive monomer state (Fig. 1A) or the fully liganded back-to-back dimer state (Fig. 1B), which explains the lack of mAb806 binding to normal tissues in which EGFR is quiescent. However, the ...
http://cancerres.aacrjournals.org/content/72/12/2924
Elevated carboxyhemoglobin in a marine mammal, the northern elephant seal | Scripps Institution of Oceanography, UC San DiegoElevated carboxyhemoglobin in a marine mammal, the northern elephant seal | Scripps Institution of Oceanography, UC San Diego
Low concentrations of endogenous carbon monoxide (CO), generated primarily through degradation of heme from hemeproteins, have been shown to maintain physiological function of organs and to exert cytoprotective effects. However, high concentrations of carboxyhemoglobin (COHb), formed by CO binding to hemoglobin, potentially prevent adequate O-2 delivery to tissues by lowering arterial O-2 content. Elevated heme-protein concentrations, as found in marine mammals, are likely associated with greater heme degradation, more endogenous CO production and, consequently, elevated COHb concentrations. Therefore, we measured COHb in elephant seals, a species with large blood volumes and elevated hemoglobin and myoglobin concentrations. The levels of COHb were positively related to the total hemoglobin concentration. The maximum COHb value was 10.4% of total hemoglobin concentration. The mean (+/- s.e.m.) value in adult seals was 8.7 +/- 0.3% (N=6), while juveniles and pups (with lower heme-protein ...
https://scripps.ucsd.edu/biblio/elevated-carboxyhemoglobin-marine-mammal-northern-elephant-seal
Dozen construction workers hospitalized after possible carbon monoxide exposureDozen construction workers hospitalized after possible carbon monoxide exposure
A dozen construction workers have been hospitalized after possible carbon monoxide exposure that happened while they were working with propane powered tools inside of building in Odenton.
https://www.fox5dc.com/news/dozen-construction-workers-hospitalized-after-possible-carbon-monoxide-exposure
Protective effect of carbon monoxide inhalation for cold-preserved small intestinal grafts<...Protective effect of carbon monoxide inhalation for cold-preserved small intestinal grafts<...
TY - JOUR. T1 - Protective effect of carbon monoxide inhalation for cold-preserved small intestinal grafts. AU - Nakao, Atsunori. AU - Kimizuka, Kei. AU - Stolz, Donna B.. AU - Neto, Joao Seda. AU - Kaizu, Takashi. AU - Choi, Augustine M.K.. AU - Uchiyama, Takashi. AU - Zuckerbraun, Brian S.. AU - Bauer, Anthony J.. AU - Nalesnik, Michael A.. AU - Otterbein, Leo E.. AU - Geller, David A.. AU - Murase, Noriko. N1 - Funding Information: Supported by NIH Grant DK54232 (Murase), CA76541 (Stolz), HL60234, AI42365, HL55330 (Choi), GM58241 and GM53789 (Bauer), and American Heart 160332U and Atorvastatin Pfizer Research Award (Otterbein) PY - 2003/8/1. Y1 - 2003/8/1. N2 - Background. Heme oxygenase (HO)-1 system has been shown to provide protection against oxidative stress through the degradation of heme to biliverdin, free iron, and carbon monoxide (CO). This study investigated cytoprotective efficacy of CO at a low concentration on cold ischemia/reperfusion (I/R) injury of transplanted intestine. ...
https://okayama.pure.elsevier.com/en/publications/protective-effect-of-carbon-monoxide-inhalation-for-cold-preserve
Carbon Monoxide Poisonings Resulting from Open Air Exposures to Operating Motorboats --- Lake Havasu City, Arizona, 2003Carbon Monoxide Poisonings Resulting from Open Air Exposures to Operating Motorboats --- Lake Havasu City, Arizona, 2003
The surveys described in this report document excessive CO exposures in employees and excessive and fatal CO exposures in vacationers amid large numbers of boats. The surveys also document substantial CO exposures in the late afternoon during crowded boating conditions, mirrored by elevations in expired CO concentrations among employees and vacationers. The majority of LHC employees had estimated %COHb levels indicating the potential for adverse health effects. Vacationers tested had higher %COHb levels than employees. These results indicate that elevated %COHb levels can occur among persons in open, outdoor settings. Previously described outdoor boat-related poisonings involved dangers to occupants of individual boats (e.g., houseboats and ski-boats) (4,5). The findings in this report are subject to at least three limitations. First, evaluation of CO-related symptoms was limited by a lack of participant information on dehydration, heat stress, physical and mental stress, and vacationer alcohol ...
https://www.cdc.gov/mmwr/preview/mmwrhtml/mm5315a3.htm
Carbon Monoxide - The Silent Killer - Fireboy-XintexCarbon Monoxide - The Silent Killer - Fireboy-Xintex
Carbon monoxide (CO) is generated wherever combustion occurs, including the operation of gasoline engines, as well as heating and cooking appliances. It is invisible, odorless, tasteless, and deadly. Faulty venting or even a wind shift can create a dangerous situation, particularly in confined areas like boat cabins. Typical symptoms of CO exposure can be mistaken for the flu or seasickness, making accurate on board CO detection a necessity.. The CO Alarm uses a microprocessor to measure and accumulate CO levels. Using the principle of Time Weighted Averaging (TWA), the CO Alarm monitors CO concentration, temperature, and time to calculate levels of Carboxyhemoglobin (COHb). COHb is the degree to which the oxygen carrying capacity of the blood is impeded by the union of carbon monoxide to the hemoglobin and is expressed as a percentage. In simpler terms, our bodies prefer absorbing CO to oxygen, and COHb is the ratio of absorbed carbon monoxide to oxygen in the bloodstream. The CO Alarm ...
http://www.fireboy-xintex.com/carbon-monoxide-silent-killer/
Most recent papers with the keyword Chemical pathology | Read by QxMDMost recent papers with the keyword Chemical pathology | Read by QxMD
There is no effective drug for the therapy of acute carbon monoxide (CO) poisoning. The purpose of the present study was to investigate the potential preventive and therapeutic effects of hemin on an animal model of acute CO poisoning and to provide a potential therapeutic candidate drug. A total of 80 Kunming mice were randomly divided into four groups, namely the air control, acute CO poisoning, hemin-treatment + CO and hemin-pretreatment + CO groups (n=20 each). Furthermore, the mortality rate of mice, blood carboxyhaemoglobin (HbCO) concentration and serum malondialdehyde (MDA) concentration were measured, and pathological changes of the hippocampal area were determined using histochemical staining ...
https://www.readbyqxmd.com/keyword/11956
Home Energy Magazine :: THE CASE OF THE CO LEAK: Solving the Mysteries of Carbon Monoxide ExposuresHome Energy Magazine :: THE CASE OF THE CO LEAK: Solving the Mysteries of Carbon Monoxide Exposures
Home Energy, the magazine of the home performance industry since 1984, publishes residential energy efficiency, comfort, safety, and green building best practices for remodelers, builders and contractors.
http://homeenergy.org/show/article/nav/troubleshooting/page/4/id/1346
Home Energy Magazine :: THE CASE OF THE CO LEAK: Solving the Mysteries of Carbon Monoxide ExposuresHome Energy Magazine :: THE CASE OF THE CO LEAK: Solving the Mysteries of Carbon Monoxide Exposures
Home Energy, the magazine of the home performance industry since 1984, publishes residential energy efficiency, comfort, safety, and green building best practices for remodelers, builders and contractors.
http://homeenergy.org/show/article/nav/troubleshooting/page/2/id/1346
DAN | Medical Frequently Asked QuestionsDAN | Medical Frequently Asked Questions
HBOT speeds the removal of CO from the body. In a study using volunteer subjects, the average time necessary to reduce blood CO levels by half, (written as T1/2, where T is time) was 320 minutes (range of 128 - 409 minutes).2 When exposed to HBOT at 3 atmospheres absolute (ATA), the T1/2 decreases to approximately 23 minutes.3 HBOT also inhibits the tissue destructive inflammatory processes instigated by CO, which can persist after CO levels drop to within normal limits. It is for this reason that measurement of CO blood concentration (abbreviated COHb - carboxyhemoglobin) alone is not the sole determinant of whether HBOT is used or a reliable measurement of poisoning severity. COHb will naturally decline with time, but tissue damage may persist after CO blood levels have declined to normal or expected levels. In cases of prolonged subacute exposure which can include warehouses, parking garages, auto shops etc.), COHb may never reach severe levels but may still produce signs of toxicity. ...
https://www.diversalertnetwork.org/medical/faq/Hyperbaric_Oxygen_Therapy_Beyond_the_Diving_Injury
MULTI-COMPONENT SPECTROPHOTOMETRIC DETERMINTION OF INACTIVE AND ACTIVE HEMOGLOBINS IN CANINE AND BOVINE BLOODMULTI-COMPONENT SPECTROPHOTOMETRIC DETERMINTION OF INACTIVE AND ACTIVE HEMOGLOBINS IN CANINE AND BOVINE BLOOD
Cairo Police Equestrian Department, Cairo, Egypt. Abstract. The fractions and concentrations of the inactive Hb pigments (such as sulfhemoglobin, SHb, methemoglobin, MetHb, carboxyhemoglobin, HbCO) and the active Hb (in the oxyhemoglobin form) as well as the total blood Hb concentration were determined in canine and bovine blood, using newly developed multi-component spectrophotometric methods. The results obtained by the cows method revealed values of MetHb% up to 4.607% and of HbCO% up to 4.814%, which are relatively higher than those values in canine blood (up to 1.385% and 3.0%, respectively). These high values of MetHb% and HbCO% in bovine blood may account for the observed decrease in the oxygen-carrying capacity of bovine blood Hb (HbO2%), when compared to canine blood. Furthermore, these methods has yielded values of the cows total blood Hb concentration up to 16.161 g dL-1 which are relatively lower than those values of dogs (up to 19.992 g dL-1). Moreover, these methods has yielded ...
https://www.rjb.ro/multi-component-spectrophotometric-determintion-of-inactive-and-active-hemoglobins-in-canine-and-bovine-blood/
Five-coordinate H64Q neuroglobin as a ligand-trap antidote for carbon monoxide poisoning | Science Translational MedicineFive-coordinate H64Q neuroglobin as a ligand-trap antidote for carbon monoxide poisoning | Science Translational Medicine
Carbon monoxide (CO) is a leading cause of poisoning deaths worldwide, with no available antidotal therapy. We introduce a potential treatment paradigm for CO poisoning, based on near-irreversible binding of CO by an engineered human neuroglobin (Ngb). Ngb is a six-coordinate hemoprotein, with the heme iron coordinated by two histidine residues. We mutated the distal histidine to glutamine (H64Q) and substituted three surface cysteines with less reactive amino acids to form a five-coordinate heme protein (Ngb-H64Q-CCC). This molecule exhibited an unusually high affinity for gaseous ligands, with a P50 (partial pressure of O2 at which hemoglobin is half-saturated) value for oxygen of 0.015 mmHg. Ngb-H64Q-CCC bound CO about 500 times more strongly than did hemoglobin. Incubation of Ngb-H64Q-CCC with 100% CO-saturated hemoglobin, either cell-free or encapsulated in human red blood cells, reduced the half-life of carboxyhemoglobin to 0.11 and 0.41 min, respectively, from ≥200 min when the ...
https://stm.sciencemag.org/content/8/368/368ra173
SPECTROSCOPIC MEASUREMENTS WITH PARALLEL ARRAY DETECTOR - Patent applicationSPECTROSCOPIC MEASUREMENTS WITH PARALLEL ARRAY DETECTOR - Patent application
TABLE-US-00001 TABLE 1 BIOMARKERS OF HEALTH/INFLAMMATION (Serum/blood concentrations) Glucose 100 mg/dL ATP 1000 nanomol/L 507.18 ng/nanomol 507 ng/ml GSH (glutathione) 15-30 micromol/L MT metallothionein 1-10 ng/g in serum or urine EPINEPHRINE Supine: , or =111 pg/mL Standing: , or =141 pg/mL NOREPINEPHRINE Supine: 70-750 pg/mL Standing: 200-1,700 pg/mL ACTH 10-60 pg/mL CORTISOL 7-25 mcg/dL Arginine Vasopressin Adults: ,1.7 pg/mL Prolactin Males: 3-13 ng/mL Females: 3-27 ng/mL Cytokine panel 0-5 pg/ml TESTOSTERONE, TOTAL 75-400 ng/dL Progesterone Females, 0.20-27.00 ng/mL C-reactive protein ≧150 mcg/dl HEMATOLOGY Activated Partial Thromboplastin ≧150 sec (biomarker) Time, Plasma Fibrinogen ≦60 - mg/dL Hemoglobin ,7 weeks ≦6.0 ≧ 20.0 g/dL INR (International Normalizing Ratio) - .sup. ≧5.0 (biomarker) CHEMISTRY Ammonia ,1 year - ≧500 mcg/dL Calcium, Total ≦6.5 ≧ 13.0 mg/dL Calcium, Ionized, Blood ≦3.0 ≧ 6.5 mg/dL Carbon Monoxide (Carboxyhemoglobin ≧20% Level) - Creatinine, ...
http://www.patentsencyclopedia.com/app/20160123869
Berkeley couples mysterious deaths raise public health fears - San Francisco ChronicleBerkeley couples mysterious deaths raise public health fears - San Francisco Chronicle
Medical examiners concluded that the noxious gas accidentally caused the deaths of Roger Hanna Morash, 35, and Valerie Morash, 32, after finding high levels of carboxyhemoglobin in their blood. When Roger Hanna Morashs co-worker came to the two-story apartment on the afternoon of Jan. 23 - he worked from home as a video game developer - she unlocked the apartment door to find him and a cat motionless on the floor upstairs. First responders found another cat and the body of Valerie Morash in the second-floor bedroom. All the usual suspects - heaters, stovetops, the cars in the driveway - were devoid of dangerous levels of carbon monoxide, later inspections revealed. A laser cutter and 3-D printer, which were in the office next to the couples bedroom, were dismissed as likely sources because the printer wasnt powered on and the laser cutter was plugged in to a power strip that was switched off, Bracamontes said. Dr. Paul Blanc, a professor of medicine at UCSF who specializes in occupational and
http://www.sfchronicle.com/bayarea/article/Berkeley-couple-s-mysterious-deaths-raise-11077092.php
Inhalation Study For Cigarette-Smoke-Related Lung Tumorigenicity In A/J Mice | PMI ScienceInhalation Study For Cigarette-Smoke-Related Lung Tumorigenicity In A/J Mice | PMI Science
Cigarette smoking is a major cause of lung cancer; however, it has been difficult to reproduce the tumorigenicity of cigarette smoke in preclinical animal models. Increased lung tumorigenicity has been reported in A/J mice exposed for 5 months to an environmental tobacco smoke surrogate or to cigarette mainstream smoke (MS) followed by 4 months without further exposure. Here, we report on MS-induced lung tumor formation in male a/j mice after 18 months of exposure to a continuous flow of MS (6 H/day, 5 D/wk) at total particulate matter concentrations of 150 and 300 mg/m(3). Animal health, housing conditions, test atmosphere characterization, and markers for MS exposure (e.g., carboxyhemoglobin) were carefully monitored over the 18-month period to ensure the stability of the experimental conditions. Body weight gain was reduced dose-dependently in MS-exposed groups. An influx of neutrophils (up to 33% of leukocytes) and lymphocytes (up to 21%) into the bronchoalveolar space, indicating severe ...
https://www.pmiscience.com/library/publication/inhalation-study-for-cigarette-smoke-related-lung-tumorigenicity-in-a-j-mice
Marijuana and Coronary Heart Disease - American College of CardiologyMarijuana and Coronary Heart Disease - American College of Cardiology
In patients with chronic stable angina, smoking a single marijuana cigarette decreased exercise time to angina by 48%. It is postulated that that marijuana-induced sympathetic stimulation increases myocardial oxygen demand. This, along with a decreased oxygen supply due to carboxyhemoglobin formation from inhalation of products of combustion in the marijuana cigarette, decreases the exercise capacity.19. To determine the role of marijuana as a trigger for acute coronary syndrome (ACS), Mittelman et al. performed a case-crossover analysis on 3,882 patients from Onset (Determinants of Myocardial Infarction Onset Study). Among 3,882 patients, 124 reported marijuana use in the past year. The authors found an elevated risk up to 4.8 times for MI within 1 hour of use of marijuana. The risk declined rapidly after 1 hour. It should be noted that the number of patients who reported marijuana use constituted only 3.2% of the entire group. A calculated annual risk of 1.5-3% of acute cardiovascular event ...
http://www.acc.org/latest-in-cardiology/articles/2016/09/22/08/58/marijuana-and-coronary-heart-disease
Cost Of Fluoxetine 20 mg Without InsuranceCost Of Fluoxetine 20 mg Without Insurance
Laboratories routinely measure patient serum cost of plan b at rite aid sells or vascular death from 5.83% to the FDA compared the drug is the biology of oxidative phosphorylation. Many tests can be excreted in intestinal absorption, where k21 is begun, scaling, socioeconomic status, and amiodarone via disruption of compartment 1, may not have actively harbored the most common drug-induced respiratory problem. The rhabditiform larvae (male and other tissues and play a combined analysis, and 7, blood or potentially life-limiting illness, and is indicated and attention deficit hyperactivity disorder. Pulse oximeters do not measure carboxyhemoglobin, at the patient to endogenous thrombopoietin. Myocardial perfusion effexor cost generic imaging can be conducted to 5.32% (P = 0.043). However, but it is the pharmacologic effect elicited by the drug, dose, in individuals with similar backgrounds, and severity of myocyte cost of fluoxetine 20 mg without insurance uptake is and arthritis. A recent study ...
http://ip-173-201-96-207.ip.secureserver.net/shop/cost-of-fluoxetine-20-mg-without-insurance
December, 2006 - archive - scubadoc Ten Foot StopDecember, 2006 - archive - scubadoc Ten Foot Stop
The Pacific Chapter held its Annual Conference at historic Jack London Square in Oakland, CA on September 15 & 16. The conference was organized by the current chapter president, Lorre Henderson, OD, MD with approximately 60 in attendance. The first day started off with a lecture by Dr. Neil Hampson on Carboxyhemoglobin followed by a fascinating look at medical problems encountered in the sport of free diving given by Dr. Ralph Potkin. The remainder of the day consisted of interesting scientific lectures on a variety of topics. Friday evening was spent on a delightful 3-hour cruise of San Francisco Bay aboard the USS Potomac, otherwise know as the Floating White House, used by FDR during his tenure as President of the United States. Saturday was diving day consisting for lectures pertinent to the subject. The Presidents gavel was handed over to Ralph Potkin, MD and plans are underway for next years conference which is tentatively sceduled to take place in Avelon on Catalina Island. Included ...
http://www.scuba-doc.com/tenfootstop/200612.html
Worksmart - G stebuchWorksmart - G stebuch
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Aston Publications ExplorerAston Publications Explorer
Vítek, Libor; Gbelcová, Helena; Muchová, Lucie; Váňová, Kateřina; Zelenka, Jaroslav; Koníčková, Renata; Šuk, Jakub; Zadinova, Marie; Knejzlík, Zdeněk; Ahmad, Shakil; Fujisawa, Takeshi; Ahmed, Asif and Ruml, Tomáš (2014). Antiproliferative effects of carbon monoxide on pancreatic cancer. Digestive and liver disease, 46 (4), pp. 369-375. Vítek, Libor; Gbelcová, Helena; Muchová, Lucie; Váňová, Kateřina; Zelenka, Jaroslav; Koníčková, Renata; Šuk, Jakub; Zadinova, Marie; Knejzlík, Zdeněk; Ahmad, Shakil; Fujisawa, Takeshi; Ahmed, Asif and Ruml, Tomáš (2014). Antiproliferative effects of carbon monoxide on pancreatic cancer. Digestive and Liver Disease, 46 (4), pp. 369-375. Nayeri, Unzila A.; Buhimschi, Irina A.; Laky, Christine A.; Cross, Sarah N.; Duzyj, Christina M.; Ramma, Wenda; Sibai, Baha M.; Funai, Edmund F.; Ahmed, Asif and Buhimschi, Catalin S. (2014). Antenatal corticosteroids impact the inflammatory rather than the antiangiogenic profile of women with ...
https://publications.aston.ac.uk/view/author/Ahmed=3AAsif=3A=3A.html
Masimo Announces Limited Market Release of Rad-67™ rainbow® Pulse CO-Oximeter® with Next Generation SpHb® | Business WireMasimo Announces Limited Market Release of Rad-67™ rainbow® Pulse CO-Oximeter® with Next Generation SpHb® | Business Wire
Masimo (NASDAQ:MASI) announced today, in conjunction with its CE marking, the limited market release of the Spot-Check Rad-67™ Handheld Pulse CO-Oximeter®. Rad-67 offers Measure-through Motion and Low Perfusion™ SET® pulse oximetry and upgradeable rainbow® noninvasive monitoring technology in a compact, portable spot-check device. With the universal reusable rainbow® DCI®-mini sensor, Rad-67 features Next Generation SpHb® (noninvasive total hemoglobin) technology. This Smart News Release features multimedia. View the full release here: http://www.businesswire.com/news/home/20170605005349/en/ Masimo Rad-67™ Handheld Pulse CO-Oximeter® with rainbow® DCI®-mini Sensor (Photo: Business Wire) Next Generation SpHb technology offers improved motion tolerance and a faster time to display SpHb results (in as few as 30 seconds). In addition, field performanc
https://www.sttinfo.fi/tiedote/masimo-announces-limited-market-release-of-rad-67tm-rainbow-pulse-co-oximeter-with-next-generation-sphb?publisherId=58763726&releaseId=61454187
Masimo announces CE Marking of Rad-97™ Pulse CO-Oximeter®Masimo announces CE Marking of Rad-97™ Pulse CO-Oximeter®
NEUCHATEL, Switzerland - Masimo (NASDAQ: MASI) announced today the CE marking of the Rad-97™ Pulse CO-Oximeter®. Rad-97 offers the same Measure-through Motion and Low Perfusion™ SET® pulse oximetry and upgradeable rainbow SET™ technology as the Radical-7® Pulse CO-Oximeter - in a versatile standalone monitor configuration.. Rad-97 features a high-resolution 1080p HD color display with user-friendly multi-touch navigation, similar to Root® and Radical-7, allowing clinicians to easily customize the device to best suit their monitoring needs. Users can also rapidly configure the device to accommodate different patient populations using customizable profiles. Rad-97 provides both built-in wireless connectivity, via Wi-Fi and Bluetooth®, and built-in wired options, including Ethernet, USB, and Nurse Call Interface connections. A rechargeable battery lasting seven hours allows Rad-97 to be used in situations where portability or extended operation without access to power are needed.. In ...
https://www.ems1.com/ems-products/co-screening/press-releases/masimo-announces-ce-marking-of-rad-97tm-pulse-co-oximeter-QWjbHB9QRVvHz4ps/
The most common questions we get asked by people about Cuban cigars - If you are a new cigar smoker, your Simply Cigars Guide...The most common questions we get asked by people about Cuban cigars - If you are a new cigar smoker, your Simply Cigars Guide...
Each year, Habanos SA, the company in Cuba responsible of marketing and distributing Habanos worldwide, release a number of exceptional cigars known as Ediciones Limitadas or Limited Editions.. The characteristics of Limited Editions are that they are made by the most celebrated houses in Havana, in rare sizes, using dark coloured wrapper leaves and extra aged tobacco. Since 2000, when the first series of four Limited Editions was unveiled , a further three to five releases have been made annually with the year of release identified on a second band on the cigar.. The exact quantity made of each release is not declared because the Cuban industry cannot tell how many cigars of each size it will be able to make until the bales of specially aged wrapper leaves are opened and graded for quality and colour. Up until 2007, only the wrapper leaves were subjected to extra ageing (2yrs), but since then all the leaves used for Limited Editions carry this extra age.. ...
https://www.simplycigars.co.uk/guide/cuban-cigar-questions-2307/
Propaq<sup>®...Propaq<sup>®...
This collection of instructional videos for the ZOLL Propaq M in English reviews topics such as monitoring, capnography, pulse CO-oximetry, invasive pressures and battery management.
https://www.zoll.com/ca/contact/elearning/videos/propaq-m
Patente US5045529 - Tonometric fluid for blood gas and co-oximetry instruments - Google PatentesPatente US5045529 - Tonometric fluid for blood gas and co-oximetry instruments - Google Patentes
A stable reference solution for calibrating and monitoring blood gas instrumentation is disclosed. The solution comprises an aqueous mixture containing a hemoglobin solution derived from a mammalian source which comprises at least about 95% reduced hemoglobin. The solution additionally contains a bicarbonate buffer and a metal catalyzed methemoglobin reducing system and an organic buffer. To provide a control element having a variety of properties similar to fresh, whole, human blood, the reference solution is stored in a sealed ampule under an inert atmosphere containing CO2 until just prior to use. The ampule is subsequently opened and the solution is equilibrated with a gas mixture having components which provide gasses in a physiological range to the solution. The solution is characterized by exhibiting properties similar to fresh blood subsequent to equilibration and an extended storage life prior to equilibration.
http://www.google.es/patents/US5045529
Sensors and MaterialsSensors and Materials
Because carbon monoxide (CO) is a colorless and odorless gas, symptoms of CO poisoning are difficult to recognize, making CO a hidden killer in home environments. To prevent CO poisoning, we used artificial intelligence and Internet of Things (IoT) technology to develop a CO poisoning prevention system with the following functional features: (1) a CO sensor, which was installed in the bathroom at home and immediately activated to warn the household when the CO concentration was excessively high; (2) an electric window opener and a fan, which when activated performed forced ventilation and thereby reduced CO concentration; (3) a device that cut off the gas supply; (4) a Line application that notified family members and signaled the community management center to conduct emergency rescue operations; and (5) a mechanism for unlocking the door to allow people to enter for emergency rescue. The obtained results may help reduce the number of CO poisoning cases and casualties in the winter in Taiwan ...
https://myukk.org/SM2017/article.php?ss=2482
Cigar and pipe smoking and cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC). - Cancer...Cigar and pipe smoking and cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC). - Cancer...
The carcinogenicity of cigar and pipe smoking is established but the effect of detailed smoking characteristics is less well defined. We examined the effects on cancer incidence of exclusive cigar and pipe smoking, and in combination with cigarettes, among 102,395 men from Denmark, Germany, Spain, Sweden and the United Kingdom in the EPIC cohort. Hazard ratios (HR) and their 95% confidence intervals (CI) for cancer during a median 9-year follow-up from ages 35 to 70 years were estimated using proportional hazards models. Compared to never smokers, HR of cancers of lung, upper aerodigestive tract and bladder combined was 2.2 (95% CI: 1.3, 3.8) for exclusive cigar smokers (16 cases), 3.0 (2.1, 4.5) for exclusive pipe smokers (33 cases) and 5.3 (4.4, 6.4) for exclusive cigarette smokers (1,069 cases). For each smoking type, effects were stronger in current smokers than in ex-smokers and in inhalers than in non-inhalers. Ever smokers of both cigarettes and cigars [HR 5.7 (4.4, 7.3), 120 cases] and
https://www.ceu.ox.ac.uk/publications/556796
How Heart Disease May Have Led to James Gandolfinis Death | Medicine HunterHow Heart Disease May Have Led to James Gandolfinis Death | Medicine Hunter
James Gandolfini, the larger-than-life Emmy award-winning actor who played mob boss Tony Soprano, has met his end in Rome, due to an apparent heart attack. At age 51, his passing was entirely premature. As Tony Soprano, Gandolfini insinuated himself into popular culture as the big, menacing, complex and implacable mobster who ruled his criminal empire with old-school, strong-arm tactics. But every tough guy knows that theres someone - or something - tougher out there. For Tony Soprano, the hit man was likely heart disease.. The much-beloved Gandolfini was by all accounts a marvelous friend and deeply respected by his peers. He had a charismatic personality and a great sense of humor. He was also very overweight, a cigar smoker and a man known to remain at the dinner table until the last strands of pasta and crumbs of tiramisu had been taken care of. As Tony Soprano, he could menace just about anybody. But as actor Gandolfini, his lifestyle vulnerabilities made him an easy target for a highly ...
http://www.medicinehunter.com/James-Gandolfini
EnglishEnglish
The main objective ofthis paper is to present a new program thatfacilitates the management of people who want to quit smoking, implemented through an e-treatment software called S-PC (Smoker Patient Control). S-PC is a web-based application that manages groups of patients, provides a bidirectional communication through mobile text messages and e-mails between patients and clinicians and offers advice and control to keep track of the patients and their status. A total of 229 patients were enrolled in the study, randomly divided into two groups, although some variables were tested to ensure that there were no significant differences between the groups that could have an impact on the outcome of the treatment. There were no significant differences between the two groups regarding the ratio/number of males/females, tobacco dependence, co-oximetry, average cigarette consumption, current age and age when smoking started. The first group was made up of 104 patients (45.4% of the total) and followed a ...
https://repositori.udl.cat/handle/10459.1/57202?locale-attribute=en
Carbon monoxideCarbon monoxide
Additionally, a noninvasive carboxyhemoglobin (SpCO) test method from Pulse CO-Oximetry exists and has been validated compared ... Concentrations as low as 667 ppm may cause up to 50% of the body's hemoglobin to convert to carboxyhemoglobin. A level of 50% ... Normal circulating levels in the blood are 0% to 3% saturation, i.e. the ratio of the amount of carboxyhaemoglobin present to ... This process produces a certain amount of carboxyhemoglobin in normal persons, even if they do not breathe any carbon monoxide ...
https://en.wikipedia.org/wiki/Carbon_monoxide
Carbon monoxide poisoningCarbon monoxide poisoning
A CO-oximeter can be used to determine carboxyhemoglobin levels. Pulse CO-oximeters estimate carboxyhemoglobin with a non- ... The ratio of carboxyhemoglobin to hemoglobin molecules in an average person may be up to 5%, although cigarette smokers who ... Carboxyhemoglobin levels have been shown to have a strong correlation with breath CO concentration. However, many of these ... This results following a recurrence of increased carboxyhemoglobin levels; this effect may be due to a late release of carbon ...
https://en.wikipedia.org/wiki/Carbon_monoxide_poisoning
CO-oximeterCO-oximeter
More recently, some 'pulse' or more precisely 'peripheral' oximeters have made it possible to estimate carboxyhemoglobin with ... carboxyhemoglobin and methemoglobin. Crit Care International, April-May, 8-9, 1995. Moran RF, The case for standardized ... as well as the dyshemoglobins such as carboxyhemoglobin (COHb) and methemoglobin (MetHb). The use of 'CO' rather than 'Co' or ' ... "Spectrophotometric measurement of carboxyhemoglobin and methemoglobin in blood". Clinical Chemistry. 25 (8): 1388-93. PMID ...
https://en.wikipedia.org/wiki/CO-oximeter
IronIron
Hemoglobin bound to carbon monoxide is known as carboxyhemoglobin. This effect also plays a minor role in the toxicity of ... Gregory B. Vásquez; Xinhua Ji; Clara Fronticelli; Gary L. Gilliland (1998). "Human Carboxyhemoglobin at 2.2 Å Resolution: ...
https://en.wikipedia.org/wiki/Iron
Pulse oximetryPulse oximetry
UK 2320566 Maisel WH, Lewis RJ (October 2010). "Noninvasive measurement of carboxyhemoglobin: how accurate is accurate enough ... By using additional wavelengths, it provides clinicians a way to measure the dyshemoglobins, carboxyhemoglobin, and ...
https://en.wikipedia.org/wiki/Pulse_oximetry
Breath carbon monoxideBreath carbon monoxide
This is known as "Fetal carboxyhaemoglobin" (%FCOHb). This level has also been found to be on average 1.8 times higher in the ... Maisel, William; Roger J. Lewis (2010). "apple Measurement of Carboxyhemoglobin: How Accurate is Accurate Enough?". Annals of ... carbon monoxide level has been shown to have a close relationship with the level of CO in the blood known as carboxyhaemoglobin ...
https://en.wikipedia.org/wiki/Breath_carbon_monoxide
Respiratory tract infectionRespiratory tract infection
Zavorsky, Gerald S. (2012). "The rise in carboxyhemoglobin from repeated pulmonary diffusing capacity tests". Respiratory ...
https://en.wikipedia.org/wiki/Respiratory_tract_infection
Exhaust gasExhaust gas
It combines with hemoglobin to produce carboxyhemoglobin, which blocks the transport of oxygen. At concentrations above 1000ppm ...
https://en.wikipedia.org/wiki/Exhaust_gas
Diffusing capacity for carbon monoxideDiffusing capacity for carbon monoxide
Expected DLCO is also affected by the amount of hemoglobin, carboxyhemoglobin, age and sex. The correction for hemoglobin is ...
https://en.wikipedia.org/wiki/Diffusing_capacity_for_carbon_monoxide
Oxygen-hemoglobin dissociation curveOxygen-hemoglobin dissociation curve
The reaction HbO2 + CO → HbCO + O2 almost irreversibly displaces the oxygen molecules forming carboxyhemoglobin; the binding of ... a person can suffer from severe tissue hypoxia while maintaining a normal pO2 because carboxyhemoglobin does not carry oxygen ...
https://en.wikipedia.org/wiki/Oxygen–hemoglobin_dissociation_curve
Hypoxia (medical)Hypoxia (medical)
Wald, NJ; Idle, M; Boreham, J; Bailey, A (May 1981). "Carbon monoxide in breath in relation to smoking and carboxyhaemoglobin ...
https://en.wikipedia.org/wiki/Hypoxia_(medical)
Smoke inhalationSmoke inhalation
Weaver LK, Howe S, Hopkins R, Chan KJ (2000). "Carboxyhemoglobin half-life in carbon monoxide-poisoned patients treated with ...
https://en.wikipedia.org/wiki/Smoke_inhalation
BloodBlood
... in carbon monoxide poisoning is bright red, because carbon monoxide causes the formation of carboxyhemoglobin. In cyanide ... because carbon monoxide irreversibly binds to hemoglobin to form carboxyhemoglobin, so that less hemoglobin is free to bind ...
https://en.wikipedia.org/wiki/Blood
Kleihauer-Betke testKleihauer-Betke test
... or carboxyhemoglobin. Methods developed by Schneider and Ludwig and Bartsch' are recommended. For determination of the ...
https://en.wikipedia.org/wiki/Kleihauer–Betke_test
Arterial blood gas testArterial blood gas test
... carboxyhemoglobin, and methemoglobin. ABG testing is mainly used in pulmonology and critical-care medicine to determine gas ...
https://en.wikipedia.org/wiki/Arterial_blood_gas_test
Heating, ventilation, and air conditioningHeating, ventilation, and air conditioning
Carbon monoxide binds with hemoglobin in the blood, forming carboxyhemoglobin, reducing the blood's ability to transport oxygen ...
https://en.wikipedia.org/wiki/Heating,_ventilation,_and_air_conditioning
List of accidents and incidents involving the DC-3 since 2000List of accidents and incidents involving the DC-3 since 2000
Both crew members were found to have high levels of carboxyhaemoglobin in their blood. The flight had departed from Points ...
https://en.wikipedia.org/wiki/List_of_accidents_and_incidents_involving_the_DC-3_since_2000
Hypoxia (medical)Hypoxia (medical)
"Carbon monoxide in breath in relation to smoking and carboxyhaemoglobin levels". Thorax. 36 (5): 366-69. doi:10.1136/thx.36.5. ...
https://en.wikipedia.org/wiki/Hypoxia_
Carbon monoxide-releasing moleculesCarbon monoxide-releasing molecules
The average carboxyhemoglobin (CO-Hb) level in a non-smoker is between 0.2% and 0.85% CO-Hb (whereas a smoker may have between ... lyated bovine carboxyhemoglobin and maleimide PEG conjugated human carboxyhemoglobin. Porphyrin structures such as heme, hemin ... Carboxyhemoglobin can be infused to deliver CO. The most common approaches are based on polyethylene glycol (PEG)- ... Methylene chloride was the first organic CORM orally administered based on previous reports of carboxyhemoglobin formation via ...
https://en.wikipedia.org/wiki/Carbon_monoxide-releasing_molecules
Grinker myelinopathyGrinker myelinopathy
... while the standard oxygen treatment normalizes carboxyhemoglobin levels. Another preventative measure one can take is to be on ...
https://en.wikipedia.org/wiki/Grinker_myelinopathy
Dupont Plaza Hotel arsonDupont Plaza Hotel arson
"Analysis Of Carboxyhemoglobin And Cyanide In Blood From Victims Of The Dupont Plaza Hotel Fire In Puerto Rico" (PDF). Fire.nist ...
https://en.wikipedia.org/wiki/Dupont_Plaza_Hotel_arson
Metal carbonylMetal carbonyl
Vásquez, G. B.; Ji, X.; Fronticelli, C.; Gilliland, G. L. (1998). "Human Carboxyhemoglobin at 2.2 Å Resolution: Structure and ... in part because of their ability to carbonylate hemoglobin to give carboxyhemoglobin, which prevents the binding of oxygen. The ...
https://en.wikipedia.org/wiki/Metal_carbonyl
Tobacco smokingTobacco smoking
Turner, JA; Sillett, RW; McNicol, MW (1977). "Effect of cigar smoking on carboxyhemoglobin and plasma nicotine concentrations ...
https://en.wikipedia.org/wiki/Tobacco_smoking
Red blood cellRed blood cell
Hemoglobin also has a very high affinity for carbon monoxide, forming carboxyhemoglobin which is a very bright red in color. ...
https://en.wikipedia.org/wiki/Red_blood_cell
Gaseous signaling moleculesGaseous signaling molecules
This process produces a certain amount of carboxyhemoglobin in normal persons, even if they do not breathe any carbon monoxide ...
https://en.wikipedia.org/wiki/Gaseous_signaling_molecules
S7 Airlines Flight 778S7 Airlines Flight 778
One flight attendant was found with a total of 85% of carboxyhemoglobin concentration inside her blood, along with her ...
https://en.wikipedia.org/wiki/S7_Airlines_Flight_778
HVACHVAC
Carbon monoxide binds with hemoglobin in the blood, forming carboxyhemoglobin, reducing the blood's ability to transport oxygen ...
https://en.wikipedia.org/wiki/Computer_Room_Air_Conditioner
IronIron
A heme unit of human carboxyhemoglobin, showing the carbonyl ligand at the apical position, trans to the histidine residue.[147 ... Hemoglobin bound to carbon monoxide is known as carboxyhemoglobin. This effect also plays a minor role in the toxicity of ... "Human Carboxyhemoglobin at 2.2 Å Resolution: Structure and Solvent Comparisons of R-State, R2-State and T-State Hemoglobins" ...
https://en.m.wikipedia.org/wiki/Iron
Pulse oximetryPulse oximetry
Maisel, William; Roger J. Lewis (2010). "Noninvasive Measurement of Carboxyhemoglobin: How Accurate is Accurate Enough?". ... carboxyhemoglobin, and methemoglobin along with total hemoglobin.[47] ...
https://en.m.wikipedia.org/wiki/Pulse_oximetry
Carboxyhemoglobin - WikipediaCarboxyhemoglobin - Wikipedia
Carboxyhemoglobin or carboxyhaemoglobin (symbol COHb or HbCO) is a stable complex of carbon monoxide and hemoglobin (Hb) that ... Exposure to small concentrations of CO hinder the ability of Hb to deliver oxygen to the body, because carboxyhemoglobin forms ... This process produces a certain amount of carboxyhemoglobin in normal persons, even if they do not breathe carbon monoxide. ... Vásquez GB, Ji X, Fronticelli C, Gilliland GL (1998). "Human Carboxyhemoglobin at 2.2 Å Resolution: Structure and Solvent ...
https://en.wikipedia.org/wiki/Carboxyhemoglobin
Plus itPlus it
Variations in Carboxyhaemoglobin Levels in Smokers Br Med J 1974; 4 :736 ... Three experiments on smokers have been performed to determine variations in blood levels of carboxyhaemoglobin (COHb) ... Variations in Carboxyhaemoglobin Levels in Smokers. Br Med J 1974; 4 doi: https://doi.org/10.1136/bmj.4.5947.736 (Published 28 ...
http://www.bmj.com/content/4/5947/736
Carboxyhemoglobin Elevation after Exposure to Dichloromethane | ScienceCarboxyhemoglobin Elevation after Exposure to Dichloromethane | Science
Carboxyhemoglobin Elevation after Exposure to Dichloromethane. By Richard D. Stewart, Terrance N. Fisher, Michael J. Hosko, ... Carboxyhemoglobin Elevation after Exposure to Dichloromethane. By Richard D. Stewart, Terrance N. Fisher, Michael J. Hosko, ... Carboxyhemoglobin Elevation after Exposure to Dichloromethane Message Subject. (Your Name) has forwarded a page to you from ...
http://science.sciencemag.org/content/176/4032/295
Evaluation of nicotine, cotinine, thiocyanate, carboxyhemoglobin, and expired carbon monoxide as biochemical tobacco smoke...Evaluation of nicotine, cotinine, thiocyanate, carboxyhemoglobin, and expired carbon monoxide as biochemical tobacco smoke...
Evaluation of nicotine, cotinine, thiocyanate, carboxyhemoglobin, and expired carbon monoxide as biochemical tobacco smoke ... as well as carboxyhemoglobin (COHb) and expired carbon monoxide (COex) were determined. All tobacco smoke uptake parameters ( ...
https://www.ncbi.nlm.nih.gov/pubmed/3258284?dopt=Abstract
Measurement of Carboxyhemoglobin by Gas Chromatography as an Index of Hemolysis - Full Text View - ClinicalTrials.govMeasurement of Carboxyhemoglobin by Gas Chromatography as an Index of Hemolysis - Full Text View - ClinicalTrials.gov
Measurement of Carboxyhemoglobin by Gas Chromatography as an Index of Hemolysis. The safety and scientific validity of this ... Measurement of Carboxyhemoglobin by Gas Chromatography as an Index of Hemolysis in ABO-compatible and Incompatible Healthy Term ... A very accurate and reliable laboratory measure of red blood cell destruction is the plasma carboxyhemoglobin level (COHb). ...
https://clinicaltrials.gov/ct2/show/NCT00917007?recr=Open&cond=%22Fetal+Diseases%22&rank=11
COMPLICATIONS RELATED CARBOXYHEMOGLOBIN LEVELS IN SECOND HAND SMOKING PEDIATRIC TONSILLECTOMY PATIENTS - Full Text View -...COMPLICATIONS RELATED CARBOXYHEMOGLOBIN LEVELS IN SECOND HAND SMOKING PEDIATRIC TONSILLECTOMY PATIENTS - Full Text View -...
COMPLICATIONS RELATED CARBOXYHEMOGLOBIN LEVELS IN SECOND HAND SMOKING PEDIATRIC TONSILLECTOMY PATIENTS. The safety and ... Correlation between carboxyhemoglobin levels and pain of the second hand smoking children [ Time Frame: postoperative 24 hours ... Correlation between carboxyhemoglobin levels of the second hand smoking children and intraoperative bleeding volume [ Time ... The purpose of this study was to determine whether high carboxyhemoglobin level is a risk factor for postoperative adverse ...
https://clinicaltrials.gov/ct2/show/NCT01942252?term=%22secondhand+smoke%22&recr=Open&rank=5
Method for noninvasive (in-vivo) total hemoglobin, oxyhemogolobin, deoxyhemoglobin, carboxyhemoglobin and methemoglobin...Method for noninvasive (in-vivo) total hemoglobin, oxyhemogolobin, deoxyhemoglobin, carboxyhemoglobin and methemoglobin...
Method for noninvasive (in-vivo) total hemoglobin, oxyhemogolobin, deoxyhemoglobin, carboxyhemoglobin and methemoglobin ... At 548 nm, there is a triple isosbestic point for oxy-, deoxy- and carboxyhemoglobin. At this point these species have an ... In addition, a triple isosbestic point for oxy-, deoxy-, and carboxyhemoglobin is apparent at 548 nm. At this point, the ... The Coming Co-Oximeter 2500 measures total hemoglobin, oxyhemoglobin, deoxyhemoglobin, carboxyhemoglobin, methemoglobin and ...
http://www.freepatentsonline.com/5692503.html
Carboxyhaemoglobin levels in workers in Leicestershire garages. | Occupational & Environmental MedicineCarboxyhaemoglobin levels in workers in Leicestershire garages. | Occupational & Environmental Medicine
Blood carboxyhaemoglobin (HbCO%) levels were measured in 61 workers in 35 garages in Leicester and Leicestershire. Of 26 ...
http://oem.bmj.com/content/36/3/238
Carboxyhaemoglobin levels in water-pipe and cigarette smokersCarboxyhaemoglobin levels in water-pipe and cigarette smokers
The carboxyhaemoglobin (COHb) level in the blood (half-life 2 -6 hours) after inhalation of CO will depend on concentrations of ... Carboxyhaemoglobin concentrations in smokers of zheesha and cigarettes in Saudi Arabia. BMJ 1985; 291: 1768-1770. [ Links ]. ... AIM: We aimed to measure carboxyhaemoglobin (COHb) blood levels before and after water-pipe and cigarette smoking sessions. ...
http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0256-95742010000200021&lng=pt&nrm=iso&tlng=en
Prevalence of Causes of Symptom: Elevated carboxyhaemoglobin - RightDiagnosis.comPrevalence of Causes of Symptom: Elevated carboxyhaemoglobin - RightDiagnosis.com
Prevalence or incidence of diseases and medical conditions possibly causing symptom Elevated carboxyhaemoglobin as a symptom, ... Related medical articles for symptom Elevated carboxyhaemoglobin: *Symptom: Elevated carboxyhaemoglobin *Possible causes of ... Elevated carboxyhaemoglobin type of: Red blood cell symptoms (849 causes), Blood symptoms (2053 causes), Abnormal blood test ... Symptoms related to Elevated carboxyhaemoglobin: Carbon monoxide poisoning, Carbon dioxide, Oxy haemoglobin, Suffocation (3 ...
https://www.rightdiagnosis.com/symptoms/elevated_carboxyhaemoglobin.htm
Elevated carboxyhemoglobin in a marine mammal, the northern elephant seal | Scripps Institution of Oceanography, UC San DiegoElevated carboxyhemoglobin in a marine mammal, the northern elephant seal | Scripps Institution of Oceanography, UC San Diego
Elevated carboxyhemoglobin in a marine mammal, the northern elephant seal Elevated carboxyhemoglobin in a marine mammal, the ... However, high concentrations of carboxyhemoglobin (COHb), formed by CO binding to hemoglobin, potentially prevent adequate O-2 ...
https://scripps.ucsd.edu/biblio/elevated-carboxyhemoglobin-marine-mammal-northern-elephant-seal
Is alveolar carbon monoxide an unreliable index of carboxyhaemoglobin changes during smoking in man? | Clinical Science |...Is alveolar carbon monoxide an unreliable index of carboxyhaemoglobin changes during smoking in man? | Clinical Science |...
Is alveolar carbon monoxide an unreliable index of carboxyhaemoglobin changes during smoking in man? Andrew R. Guyatt; Andrew R ... 2. In seven subjects where the carboxyhaemoglobin level was raised by breathing a 2% CO gas mixture, the alveolar CO and ... The mean relative boosts ([post value-pre value]/[pre + post]/2) for alveolar CO and carboxyhaemoglobin were 7.7% and 20.3%, ... 3. We conclude that alveolar CO measurements give a useful estimate of carboxyhaemoglobin level if the subject has not smoked ...
https://portlandpress.com/clinsci/article-abstract/74/1/29/74345/Is-alveolar-carbon-monoxide-an-unreliable-index-of?redirectedFrom=fulltext
Carboxyhemoglobin and Methemoglobin as Markers of Postoperative Pulmonary ComplicationsCarboxyhemoglobin and Methemoglobin as Markers of Postoperative Pulmonary Complications
Postoperative carboxyhemoglobin was higher in smokers compared to control non-smokers group (p = 0.000). On the other hand, ... In both groups carboxyhemoglobin and methemoglobin levels were determined preoperatively, after preoxygenation, and one hour ... Determination of the level of carboxyhemoglobin and methemoglobin can identify patients with increased risk for development of ... we cannot confirm the hypothesis that carboxyhemoglobin and methemoglobin can serve as predictors for postoperative pulmonary ...
https://www.ommegaonline.org/article-details/Carboxyhemoglobin-and-Methemoglobin-as-Markers-of-Postoperative-Pulmonary-Complications/1828
Carboxyhaemoglobin)? - ????? ????????? ??????? 999Carboxyhaemoglobin)? - ????? ????????? ??????? 999
???????????????? (Carboxyhaemoglobin) - ???????? ??????????, ?????? ??? ??? ????????????? ??? ???????? ??????? ?????? ??? ????????????. ???????????????? ??????? ?????????? ?????? ???? ?????????, ??????? ??? ????????? ??? ???????? ??????? ??? ??? ??????? ???? . ??? ?????????? ???????????????? ????????? ??? ????????? ??? ????????, ?????? ?????? ??????????? ??? ??????? ?????? ??? ?????? ?????? ?????? .
http://www.tridevyatki.ru/lib/index.php?chapter=376&word=32963
Spectrophotometric measurement of carboxyhemoglobin and methem...Spectrophotometric measurement of carboxyhemoglobin and methem...
Spectrophotometric measurement of carboxyhemoglobin and methemoglobin in blood.: This paper describes separate ... Spectrophotometric measurement of carboxyhemoglobin and methemoglobin in blood.. Authors * Rodkey, F L ... This paper describes separate spectrophotometric procedures for rapidly measuring carboxyhemoglobin (COHb) and methemoglobin ( ...
https://www.mysciencework.com/publication/show/spectrophotometric-measurement-carboxyhemoglobin-methemoglobin-blood-736bbb9c
Carboxyhemoglobin definition, causes, symptoms, test, levels & treatmentCarboxyhemoglobin definition, causes, symptoms, test, levels & treatment
What are normal and elevated carboxyhemoglobin levels. Carboxyhemoglobin treatment ... What is carboxyhemoglobin. Carboxyhemoglobin (COHb) is formed by the binding of carbon monoxide (CO) to hemoglobin (Hb). High ... Carboxyhemoglobin sources. Physiologic. Carboxyhemoglobin levels increase as a result of hemolysis. Carbon monoxide is a ... The clearance of carboxyhemoglobin in methylene chloride poisoning is prolonged. The half-life of carboxyhemoglobin in this ...
http://healthjade.net/carboxyhemoglobin/
Toxicity of Carbon Monoxide-Hydrogen Cyanide Gas Mixtures: Expose Concentration, Time-to-Incapacitation, Carboxyhemoglobin, and...Toxicity of Carbon Monoxide-Hydrogen Cyanide Gas Mixtures: Expose Concentration, Time-to-Incapacitation, Carboxyhemoglobin, and...
... but the resulting concentrations of carboxyhemoglobin COHb and blood cyanide CN- at incapacitation are not well defined. These ... Toxicity of Carbon Monoxide-Hydrogen Cyanide Gas Mixtures: Expose Concentration, Time-to-Incapacitation, Carboxyhemoglobin, and ... but the resulting concentrations of carboxyhemoglobin COHb and blood cyanide CN- at incapacitation are not well defined. These ...
https://apps.dtic.mil/sti/citations/ADA279137
EF | definition of EF by Medical dictionaryEF | definition of EF by Medical dictionary
carboxyhemoglobin fraction. The percentage of total hemoglobin in a blood sample that is covalently bonded to carbon monoxide. ... 2. The ratio of a component to the total, e.g., the substance fraction of carboxyhemoglobin (relative to the total hemoglobin). ...
https://medical-dictionary.thefreedictionary.com/ef
Electronic Code of Federal Regulations (eCFR)Electronic Code of Federal Regulations (eCFR)
864.7425 Carboxyhemoglobin assay.. (a) Identification. A carboxyhemoglobin assay is a device used to determine the ... 864.7425 Carboxyhemoglobin assay.. §864.7440 Electrophoretic hemoglobin analysis system.. §864.7455 Fetal hemoglobin assay.. § ... carboxyhemoglobin (the compound formed when hemoglobin is exposed to carbon monoxide) content of human blood as an aid in the ...
https://www.ecfr.gov/cgi-bin/retrieveECFR?gp=&mc=true&n=pt21.8.864&r=PART&ty=HTML
Carbon monoxide poisoningCarbon monoxide poisoning
Carboxyhemoglobin. Levels of carbon monoxide bound in the blood can be determined by measuring carboxyhemoglobin, which is a ... Normal carboxyhemoglobin levels in an average person are less than 5%, whereas cigarette smokers (two packs/day) may have ... Serious toxicity is often associated with carboxyhemoglobin levels above 25%, and the risk of fatality is high with levels over ... Hemoglobin acquires a bright red color when converted to carboxyhemoglobin, so a casualty of CO poisoning is described in ...
https://www.bionity.com/en/encyclopedia/Carbon_monoxide_poisoning.html
NIOSHTIC-2 Publications Search - 00127268 - Health hazard evlauation report: HETA-81-299-1201, United States Steel Company-...NIOSHTIC-2 Publications Search - 00127268 - Health hazard evlauation report: HETA-81-299-1201, United States Steel Company-...
Exposures were compared to the NIOSH CO standard of 35 parts per million (ppm), which is designed to limit carboxyhemoglobin ... but no significant trend was noted in carboxyhemoglobin concentrations. The authors conclude that there is no evidence of ...
https://www.cdc.gov/niosh/nioshtic-2/00127268.html
Aggravation of exercise performance in patients with anemia by 3% carboxyhemoglobin<...Aggravation of exercise performance in patients with anemia by 3% carboxyhemoglobin<...
... carboxyhemoglobin. Together they form a unique fingerprint. * Carboxyhemoglobin Medicine & Life Sciences ... Mean carboxyhemoglobin levels increased from 2.14 to 3.38% after breathing CO and decreased from 2.15 to 1.86% after breathing ... Mean carboxyhemoglobin levels increased from 2.14 to 3.38% after breathing CO and decreased from 2.15 to 1.86% after breathing ... Mean carboxyhemoglobin levels increased from 2.14 to 3.38% after breathing CO and decreased from 2.15 to 1.86% after breathing ...
https://creighton.pure.elsevier.com/en/publications/aggravation-of-exercise-performance-in-patients-with-anemia-by-3-
Gas Education | Fundamentals of Gas Detectors | Industrial ScientificGas Education | Fundamentals of Gas Detectors | Industrial Scientific
Carboxyhemoglobin Levels. Learn how to measure the amount of Carbon Monoxide that has been absorbed into the blood stream. ...
https://indsci.com/en/training/general-gas-education/
Carbon Monoxide Safety | Taylor, MICarbon Monoxide Safety | Taylor, MI
Carboxyhemoglobin (COHb). Carboxyhemoglobin can cause headaches, fatigue, nausea, dizzy spells, confusion and irritability. ... When CO is breathed in by an individual, it accumulates in the blood and forms a toxic compound known as carboxyhemoglobin ( ... seek medical treatment or get a carboxyhemoglobin level blood test for CO poisoning. Some of the symptoms can also include are: ...
https://www.cityoftaylor.com/289/Carbon-Monoxide-Safety
Ligand dynamics in the photodissociation of carboxyhemoglobin by subpicosecond transient infrared spectroscopy<...Ligand dynamics in the photodissociation of carboxyhemoglobin by subpicosecond transient infrared spectroscopy<...
Rothberg, L. ; Jedju, T. M. ; Austin, R. H. / Ligand dynamics in the photodissociation of carboxyhemoglobin by subpicosecond ... Rothberg, L., Jedju, T. M., & Austin, R. H. (1990). Ligand dynamics in the photodissociation of carboxyhemoglobin by ... Rothberg, L, Jedju, TM & Austin, RH 1990, Ligand dynamics in the photodissociation of carboxyhemoglobin by subpicosecond ... Fingerprint Dive into the research topics of Ligand dynamics in the photodissociation of carboxyhemoglobin by subpicosecond ...
https://collaborate.princeton.edu/en/publications/ligand-dynamics-in-the-photodissociation-of-carboxyhemoglobin-by-
January 1977 - Volume 59 - Issue 1 : Plastic and Reconstructive SurgeryJanuary 1977 - Volume 59 - Issue 1 : Plastic and Reconstructive Surgery
Rapid estimation of carboxyhemoglobin level in fire fighters. Constant, Errikos Constant, Errikos Less ...
https://journals.lww.com/plasreconsurg/toc/1977/01000
Hemoglobin derivatives: MedlinePlus Medical EncyclopediaHemoglobin derivatives: MedlinePlus Medical Encyclopedia
The carboxyhemoglobin test is used to diagnose carbon monoxide poisoning. It is also used to detect changes in hemoglobin that ... Carboxyhemoglobin: An abnormal form of hemoglobin that has attached to carbon monoxide instead of oxygen or carbon dioxide. ... Carboxyhemoglobin -- less than 1.5% (but may be as high as 9% in smokers) ...
https://medlineplus.gov/ency/article/003371.htm
Recurrent Acute Life-threatening Events and Lactic Acidosis Caused by Chronic Carbon Monoxide Poisoning in an Infant | American...Recurrent Acute Life-threatening Events and Lactic Acidosis Caused by Chronic Carbon Monoxide Poisoning in an Infant | American...
carboxyhemoglobin • LCHAD = long-chain 3-OH acyl CoA dehydrogenase. The incidence of carbon monoxide (CO) poisoning is ∼3500 to ... 1987) Carboxyhemoglobin levels in patients with flu-like symptoms. Ann Emerg Med 16:782-786. ... A review of cooximetry values from her previous hospitalizations revealed slightly elevated carboxyhemoglobin (COHb) levels. ...
https://pediatrics.aappublications.org/node/6488.full.print
Corrosive Injury From Methacrylic Acid in Artificial Nail Primers: Another Hazard of Fingernail Products | American Academy of...Corrosive Injury From Methacrylic Acid in Artificial Nail Primers: Another Hazard of Fingernail Products | American Academy of...
carboxyhemoglobin • MSDS = Material Safety Data Sheets • CPSC = US Consumer Product Safety Commission • FDA = Food and Drug ...
https://pediatrics.aappublications.org/content/102/4/979?download=true
COHbCarbonMethemoglobinHemoglobinSmokersOxygenEstimation of carboxyhemoglobinLevelsHbCONonsmokersVenousMeasurementPoisoning is suspectedMethylene chlorideSymptomsInhalationPulseAbstractPATIENTSTissueFormsSignificantIncreaseBreathing roomEffects
COHb20
  • Carboxyhemoglobin or carboxyhaemoglobin (symbol COHb or HbCO) is a stable complex of carbon monoxide and hemoglobin (Hb) that forms in red blood cells upon contact with carbon monoxide (CO). Carboxyhemoglobin is often mistaken for the compound formed by the combination of carbon dioxide and hemoglobin, which is actually carbaminohemoglobin. (wikipedia.org)
  • Supplemental oxygen takes advantage of Le Chatelier's principle to quicken the decomposition of carboxyhemoglobin back to hemoglobin: HbCO + O2 ⇌ Hb + CO + O2 ⇌ HbO2 + CO COHb increases risk of blood clot. (wikipedia.org)
  • Three experiments on smokers have been performed to determine variations in blood levels of carboxyhaemoglobin (COHb) throughout the day and night and whether a random measurement of COHb gives a true estimation of a smoker's mean COHb level. (bmj.com)
  • 149 smokers, 87 non-smokers) plasma nicotine (pnic), cotinine (pcot) and thiocyanate (pSCN), urinary creatinine ratios of nicotine (unic), cotinine (ucot) and thiocyanate (uSCN) as well as carboxyhemoglobin (COHb) and expired carbon monoxide (COex) were determined. (nih.gov)
  • A very accurate and reliable laboratory measure of red blood cell destruction is the plasma carboxyhemoglobin level (COHb). (clinicaltrials.gov)
  • We aimed to measure carboxyhaemoglobin (COHb) blood levels before and after water-pipe and cigarette smoking sessions. (scielo.org.za)
  • The carboxyhaemoglobin (COHb) level in the blood (half-life 2 -6 hours) after inhalation of CO will depend on concentrations of inspired CO, duration of exposure, pulmonary ventilation and the COHb level before the inhalation. (scielo.org.za)
  • However, high concentrations of carboxyhemoglobin (COHb), formed by CO binding to hemoglobin, potentially prevent adequate O-2 delivery to tissues by lowering arterial O-2 content. (ucsd.edu)
  • This paper describes separate spectrophotometric procedures for rapidly measuring carboxyhemoglobin (COHb) and methemoglobin (MetHb) in blood. (mysciencework.com)
  • Carboxyhemoglobin (COHb) is formed by the binding of carbon monoxide (CO) to hemoglobin (Hb). (healthjade.net)
  • Carboxyhemoglobin (COHb) is a stable complex of carbon monoxide (CO) that forms in red blood cells when carbon monoxide is inhaled. (healthjade.net)
  • Exposures to CO-HCN mixtures have demonstrated that these gases have additive effects producing shorter times to incapacitation, but the resulting concentrations of carboxyhemoglobin COHb and blood cyanide CN- at incapacitation are not well defined. (dtic.mil)
  • When CO is breathed in by an individual, it accumulates in the blood and forms a toxic compound known as carboxyhemoglobin ( COHb ). (cityoftaylor.com)
  • We examined associations between carboxyhemoglobin (COHb) serum concentration-an exposure proxy for carbon monoxide (CO)-ambient CO, and ARI in both cohorts. (springer.com)
  • In addition, we determined carbon monoxide and found high amounts in the smoke being causative for high levels of carboxyhemoglobin (COHb) in the blood of smokers. (nih.gov)
  • Not only does the hemoglobin prefer CO, it holds on to the CO much more tightly, forming a complex called carboxyhemoglobin (COHb). (encyclopedia.com)
  • Participation of hypoxic hypoxia in low COHb (Carboxyhemoglobin) concentrations frequently observed in fire victims was examined using rats and rabbits exposed to low-O2 and CO gas mixtures. (biomedsearch.com)
  • Readily absorbed through the lungs, carbon monoxide binds to hemoglobin as carboxyhemoglobin (COHb). (cmaj.ca)
  • In case of CO poisoning, the reduced oxygen-carrying capacity of the blood, impairment of the cellular respiratory chain, and immune-modulating processes can lead to tissue injury in the myocardium and brain even after lowering of the carboxyhemoglobin (COHb) concentration. (aerzteblatt.de)
  • five had elevated carboxyhemoglobin (COHb) levels. (cdc.gov)
Carbon19
  • This process produces a certain amount of carboxyhemoglobin in normal persons, even if they do not breathe carbon monoxide. (wikipedia.org)
  • The purpose of this study was to determine whether high carboxyhemoglobin level is a risk factor for postoperative adverse events in children exposured to carbon monoxide, especially enviromental tobacco smoke. (clinicaltrials.gov)
  • Is alveolar carbon monoxide an unreliable index of carboxyhaemoglobin changes during smoking in man? (portlandpress.com)
  • 1. We measured alveolar carbon monoxide (CO) after a 20 s breath-holding period and carboxyhaemoglobin both before and after smoking a cigarette on 500 occasions (101 individuals). (portlandpress.com)
  • Carboxyhemoglobin should be measured if carbon monoxide or methylene chloride poisoning is suspected. (healthjade.net)
  • Carboxyhemoglobin is also useful in monitoring the treatment of carbon monoxide poisoning. (healthjade.net)
  • Approximately 85% of absorbed carbon monoxide binds with hemoglobin and remains in the intravascular compartment as carboxyhemoglobin. (healthjade.net)
  • Carbon monoxide poisoning needs a high concentration of O2 to replace the carboxyhemoglobin. (healthjade.net)
  • The half-life of carboxyhemoglobin in this setting is approximately 13 hours because of ongoing carbon monoxide production from methylene chloride metabolism in the liver. (healthjade.net)
  • The carboxyhemoglobin test is used to diagnose carbon monoxide poisoning . (medlineplus.gov)
  • Carboxyhemoglobin: An abnormal form of hemoglobin that has attached to carbon monoxide instead of oxygen or carbon dioxide. (medlineplus.gov)
  • Breath measurement of carbon monoxide (CO) can be rapidly performed in the emergency department setting by a reliable method that closely approximates carboxyhemoglobin. (elsevier.com)
  • The amount of conversion to carbon monoxide is significant as measured by the concentration of carboxyhemoglobin, up to 12% measured in the blood following occupational exposure of up to 610 ppm. (osha.gov)
  • Since exposure to MC also increases the carboxyhemoglobin level in the blood, ambient carbon monoxide levels would have an additive effect on that carboxyhemoglobin level. (osha.gov)
  • The gas was first identified by Joseph Priestley in the eighteenth century, but it was Claude Bernard in 1870 who discovered the affinity between carbon monoxide and haemoglobin which accounts for its deadliness: carboxyhaemoglobin is formed and oxygen transport from the lungs to the tissues disrupted. (encyclopedia.com)
  • In 1895 J. S. Haldane demonstrated that the formation of carboxyhaemoglobin is an equilibrium reaction which depends upon the relative partial pressures of carbon monoxide and oxygen in inspired gas. (encyclopedia.com)
  • Since air contains 21% oxygen this means that only 0.1% carbon monoxide in the air will eventually lead to 50% of the haemoglobin being combined to form carboxyhaemoglobin. (encyclopedia.com)
  • Therefore, the objective was to verify the association between environmental carbon monoxide and carboxyhemoglobin levels among smoking and non- smoking motorcycle taxi drivers. (bvsalud.org)
  • A longitudinal epidemiological study was carried out with 95 motorcycle taxi drivers with measurement of the environmental carbon monoxide , carboxyhemoglobin in the exhaled air in three moments with interval of six months, between June 2014 and March 2015, as well as sociodemographic and occupational characteristics of these workers . (bvsalud.org)
Methemoglobin5
  • 5. The method of claim 3 wherein the hemoglobin species is selected from the group consisting of: oxyhemoglobin, deoxyhemoglobin, carboxyhemoglobin, methemoglobin, and sulfhemoglobin. (freepatentsonline.com)
  • Determination of the level of carboxyhemoglobin and methemoglobin can identify patients with increased risk for development of postoperative pulmonary complications. (ommegaonline.org)
  • In both group's carboxyhemoglobin and methemoglobin levels were determined preoperatively, after preoxygenation, and one hour after completing the anesthesia. (ommegaonline.org)
  • however, we cannot confirm the hypothesis that carboxyhemoglobin and methemoglobin can serve as predictors for postoperative pulmonary complications. (ommegaonline.org)
  • Spectrophotometric measurement of carboxyhemoglobin and methemoglobin in blood. (mysciencework.com)
Hemoglobin3
  • 2. The ratio of a component to the total, e.g., the substance fraction of carboxyhemoglobin (relative to the total hemoglobin). (thefreedictionary.com)
  • On the other hand, CO combines with hemoglobin to produce carboxyhemoglobin, which occupies the space in hemoglobin that normally carries oxygen, but it is ineffective for delivering oxygen to bodily tissues. (zaslavsky.com.ua)
  • Apart from hemoglobin breakdown, heme compounds of cell membrane and mitochondrial enzymes may become the source of endogenous CO and carboxyhemoglobin production. (zaslavsky.com.ua)
Smokers4
  • Postoperative carboxyhemoglobin was higher in smokers compared to control non-smokers group (p = 0.000). (ommegaonline.org)
  • Smokers: Up to 10%-15% carboxyhemoglobin. (healthjade.net)
  • carboxyhemoglobin levels among smokers and non-smokers were high in the winter, fair in the spring and low in the autumn. (bvsalud.org)
  • Environmental pollution represented different levels in the four seasons of the year and significant association with carboxyhemoglobin levels.Thecarboxyhemoglobin levels were higher among smokers , with statistical significance between winter and fall seasons , while non-smokers presented normal levels, whatconfirms the direct influence of tobacco in carboxyhemoglobin levels. (bvsalud.org)
Oxygen5
  • Exposure to small concentrations of CO hinder the ability of Hb to deliver oxygen to the body, because carboxyhemoglobin forms more readily than does oxyhemoglobin (HbO2). (wikipedia.org)
  • With hyperbaric oxygen at 3 times atmospheric pressure, carboxyhemoglobin elimination half-life can be reduced even further, to about 20-30 minutes. (healthjade.net)
  • Because carboxyhaemoglobin does not carry oxygen, a level of 50% means that the oxygen carrying capacity of the blood is reduced by 50% and there is a corresponding reduction in the ability to perform maximum exercise. (encyclopedia.com)
  • The presence of carboxyhaemoglobin also diminishes the oxygen held by the normal haemoglobin, which further compounds the hypoxic effect. (encyclopedia.com)
  • Oxygen saturation accuracy in conditions of elevated carboxyhemoglobin. (clinicaltrials.gov)
Estimation of carboxyhemoglobin1
  • We have studied the results of these investigations by means of the evaluation of CO production activity and the estimation of carboxyhemoglobin content in patient blood and СO in expiratory air. (zaslavsky.com.ua)
Levels8
  • Also we want to measure bleeding volume and compare it with the carboxyhemoglobin levels. (clinicaltrials.gov)
  • Carboxyhaemoglobin levels in workers in Leicestershire garages. (bmj.com)
  • Blood carboxyhaemoglobin (HbCO%) levels were measured in 61 workers in 35 garages in Leicester and Leicestershire. (bmj.com)
  • High carboxyhemoglobin levels can be physiologic or pathologic. (healthjade.net)
  • Carboxyhemoglobin levels increase as a result of hemolysis. (healthjade.net)
  • One approach has been to use direct CO inhalation therapy at concentrations that increase carboxyhemoglobin levels to 25% after CO inhalation. (asnjournals.org)
  • The study verifies accuracy of a new pulse co-oximeter in the presence of elevated carboxyhemoglobin levels. (clinicaltrials.gov)
  • Carboxyhemoglobin levels in patients with flu-like symptoms. (mja.com.au)
HbCO1
  • Objective To investigate the effect of conventional preseratives on the stability of carboxyhemoglobin (HbCO)in the stored blood samples. (bvsalud.org)
Nonsmokers1
  • Hence, in the absence of clinical heart or lung disease, increasing carboxyhemoglobin concentrations aggravate exercise performance in nonsmokers with chronic anemia. (elsevier.com)
Venous1
  • A low baseline level of 1%-3% carboxyhemoglobin in venous blood is detectable in all people from endogenous production. (cmaj.ca)
Measurement2
  • Measurement of Carboxyhemoglobin by Gas Chromatography as an Index of Hemolysis in ABO-compatible and Incompatible Healthy Term Newborn Infants. (clinicaltrials.gov)
  • Spectrophotometric measurement of carboxyhemoglobin and methem. (mysciencework.com)
Poisoning is suspected1
  • Perform carboxyhemoglobin (COHgb) testing when CO poisoning is suspected. (cdc.gov)
Methylene chloride1
  • The clearance of carboxyhemoglobin in methylene chloride poisoning is prolonged. (healthjade.net)
Symptoms1
  • If the family's (or pet's) symptoms decrease when away from the house, seek medical treatment or get a carboxyhemoglobin level blood test for CO poisoning. (cityoftaylor.com)
Inhalation1
  • The inhalation of tobacco smoke can substantially raise the level of carboxyhemoglobin in the blood. (ommegaonline.org)
Pulse1
  • The diagnosis of CO poisoning is based on history and examination, in conjunction with an elevated carboxyhaemoglobin level determined using pulse CO-oximetry, arterial blood gas analysis or CO breath testing. (mja.com.au)
Abstract1
  • abstract = "Time-resolved infrared spectroscopy with 0.5-ps resolution is used to track the evolution of the CO stretching vibration after visible photoexcitation of carboxyhemoglobin in water at room temperature. (princeton.edu)
PATIENTS4
  • Sketch, Michael H. / Aggravation of exercise performance in patients with anemia by 3% carboxyhemoglobin . (elsevier.com)
  • Currently, many investigators consider an endogenous CO and carboxyhemoglobin production in critical states as a compensatory mechanism that promotes cytoprotection and contributes to patients' survivability. (zaslavsky.com.ua)
  • Carboxyhemoglobin blood concentration no more than 4 % was presented in the majority of foreign investigations in patients in critical states. (zaslavsky.com.ua)
  • All the patients were delivered to emergency department with normal carboxyhemoglobin blood concentration. (zaslavsky.com.ua)
Tissue1
  • Thus, excessive endogenous CO production and excessive carboxyhemoglobin generation may play a significant role in tissue damage and multiorgan dysfunction formation. (zaslavsky.com.ua)
Forms1
Significant1
  • The blood CO concentrations after the working shift showed a slight increase compared to prework values, but no significant trend was noted in carboxyhemoglobin concentrations. (cdc.gov)
Increase1
  • Fast fluid resuscitation, hypertonic solution use, epinephrine administration were associated with increase of the blood pressure, perfusion index (PI) and carboxyhemoglobin blood concentration. (zaslavsky.com.ua)
Breathing room1
  • The half-life of carboxyhemoglobin in an individual breathing room air is approximately 300 minutes. (healthjade.net)
Effects1
  • Dose-Effects Functions for Carboxyhemoglobin and Behavior. (epa.gov)
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