Carboprost

Uterotonic

Uterine atony

Prostaglandin F2alpha

Tris

Postpartum bleeding

List of MeSH codes (D10)

Tham

List of drugs: C-Ca

ATC code G02

C21H36O5

List of MeSH codes (D23)

Carboprost

Hemabate2

• Carboprost tromethamine Brand: Hemabate Class: Prostaglandins, Endocrine, Abortifacient Uses A medication called Hemabate (carboprost tromethamine) Sterile Solution contains prostaglandin, a hormone-like molecule found in the human body. (medinfo24.com)
• When assessing a patient after the administration of carboprost (Hemabate), which side effect should the nurse expect? (floridiancecourses.org)

Tromethamine injection7

• The adverse effects of carboprost tromethamine injection sterile solution are generally transient and reversible when therapy ends. (drugcentral.org)
• Their use should be considered an integral part of the management of patients undergoing abortion with carboprost tromethamine injection.Of those patients experiencing temperature elevation, approximately one-sixteenth had clinical diagnosis of endometritis. (drugcentral.org)
• Carboprost tromethamine injection sterile solution (carboprost tromethamine), like other potent oxytocic agents, should be used only with strict adherence to recommended dosages.Carboprost tromethamine injection should be used by medically trained personnel in hospital which can provide immediate intensive care and acute surgical facilities. (drugcentral.org)
• Carcinogenic bioassay studies have not been conducted in animals with carboprost tromethamine injection due to the limited indications for use and short duration of administration. (drugcentral.org)
• The Company has received 4 final approvals that includes Bepotastine Besilate Ophthalmic Solution, 1.5%, Nadolol Tablets USP, 20 mg, 40 mg, and 80 mg, Carboprost Tromethamine Injection USP, 250 mcg/mL Single-Dose Vials, Doxercalciferol Injection, 4 mcg/2 mL (2 mcg/mL) Multiple-Dose Vials. (onlinenews9.in)
• Carboprost Tromethamine Injection USP, 250 mcg/mL Single-Dose Vials. (onlinenews9.in)
• Carboprost tromethamine injection, USP sterile solution is indicated for aborting pregnancy between the 13th and 20th weeks of gestation. (onlinenews9.in)

Prostaglandin2

• Carboprost is a prostaglandin that elicits cytoprotective, anti-inflammatory, and vasoconstrictive properties and produces no coagulum. (medscape.com)
• The average peak concentrations of drug were slightly higher following each successive injection of the prostaglandin, but always decreased to levels less than the preceding peak values by two hours after each injection.Five women who had delivery spontaneously at term were treated immediately postpartum with single injection of 250 micrograms of carboprost tromethamine. (drugcentral.org)

Uterine1

• If continued inadequate uterine tone after increasing IV oxytocin rate, administer second line uterotonic (methylergonovine or carboprost) and tranexamic acid 1 gram IV over 10 minutes. (drugtopics.com)

Oxytocin1

• Their research compared mothers given carboprost tromethamine (an oxytocin inducer) injections with this injection plus motherwort injections. (plantmedicines.org)

20231

• This summary information comes from Fass Prostinfenem (carboprost) from Pfizer (2023-06-28). (janusinfo.se)

Injection1

• Aminophylline Injection IP 2.5% w/v (NLEM) Carboprost Promethamine Inj.USP 250 mg/ml Hydrocortisone sodium succinate for inj. (pdfdrug.com)

Contractions3

• Carboprost tromethamine administered intramuscularly stimulates in the gravid uterus myometrial contractions similar to labor contractions at the end of full term pregnancy. (drugcentral.org)
• Whether or not these contractions result from direct effect of carboprost on the myometrium has not been determined. (drugcentral.org)
• Nonetheless, they evacuate the products of conception from the uterus in most cases.Postpartum, the resultant myometrial contractions provide hemostasis at the site of placentation.Carboprost tromethamine also stimulates the smooth muscle of the human gastrointestinal tract. (drugcentral.org)

Diarrhea4

• Your doctor may give you medications to help with nausea, vomiting, and diarrhea when being treated with carboprost. (rxwiki.com)
• Common side effects of carboprost include vomiting, diarrhea, and nausea. (rxwiki.com)
• This activity may produce the vomiting or diarrhea or both that is common when carboprost tromethamine is used to terminate pregnancy and for use postpartum. (drugcentral.org)
• Diarrhea, which is a common side effect of carboprost. (floridiancecourses.org)

Drugs1

• Carboprost belongs to a group of drugs called prostaglandins. (rxwiki.com)

Postpartum1

• With the clinical doses of carboprost tromethamine used for the termination of pregnancy, and for use postpartum, some patients do experience transient temperature increases.In laboratory animals and in humans large doses of carboprost tromethamine can raise blood pressure, probably by contracting the vascular smooth muscle. (drugcentral.org)

Pregnancy4

• Carboprost is used to abort pregnancy and to stop bleeding after giving birth. (rxwiki.com)
• Carboprost is used to abort pregnancy between weeks 13 and 20. (rxwiki.com)
• With the doses of carboprost tromethamine used for terminating pregnancy, this effect has not been clinically significant. (drugcentral.org)
• With the clinical doses of carboprost tromethamine used for the termination of pregnancy, some patients do experience temperature increases. (drugcentral.org)

Drug2

• www.drugguide.com/ddo/view/Davis-Drug-Guide/51130/all/carboprost. (drugguide.com)
• In some patients, carboprost tromethamine may cause transient bronchoconstriction.Drug plasma concentrations were determined by radioimmunoassay in peripheral blood samples collected by different investigators from 10 patients undergoing abortion. (drugcentral.org)

Side2

• Serious side effects have been reported with carboprost. (rxwiki.com)
• This is not a complete list of carboprost side effects. (rxwiki.com)

Provide2

• What tips would you provide a friend before taking Carboprost? (rxwiki.com)
• Carboprost tromethamine should be used by medically trained personnel in a hospital which can provide immediate intensive care and acute surgical facilities. (rxwiki.com)

Experience1

• How was your experience with Carboprost? (rxwiki.com)

Termination of pregna2

• Carboprost is also used for the termination of pregnancy in the 2nd trimester. (wikipedia.org)
• With the clinical doses of carboprost tromethamine used for the termination of pregnancy, some patients do experience temperature increases. (nih.gov)

Prostaglandins1

• Carboprost belongs to a group of drugs called prostaglandins. (rxwiki.com)

Oxytocic2

• The resulting mixture of tertiary carbinols (2) is transformed to oxytocic carboprost (3) by standard transformations, including separation of diastereomers, so that the final product is the C-15 analogue. (wikipedia.org)
• Carboprost tromethamine should be used only with strict adherence to recommended dosages like other potent oxytocic agents. (rxwiki.com)

Bronchoconstriction1

• In some patients, carboprost tromethamine may cause transient bronchoconstriction. (nih.gov)

Caution2

• Carboprost should be used with caution in patients with a history of high blood pressure. (picmonic.com)
• Hypersensitivity to carboprost or any of its components is also a contraindication [5] Exert caution in asthmatic patients as carboprost may cause bronchospasm. (mdwiki.org)

Nausea1

• Your doctor may give you medications to help with nausea, vomiting, and diarrhea when being treated with carboprost. (rxwiki.com)

Pharmaceuticals1

• Carboprost-REACH (Reach Pharmaceuticals Pty Ltd)". Therapeutic Goods Administration (TGA). (wikipedia.org)

Humans2

• In laboratory animals and also in humans carboprost tromethamine can elevate body temperature. (nih.gov)
• In laboratory animals and in humans large doses of carboprost tromethamine can raise blood pressure, probably by contracting the vascular smooth muscle. (nih.gov)

Patients2

• The patients had been injected intramuscularly with 250 micrograms of carboprost at two-hour intervals. (nih.gov)
• The highest concentration of carboprost tromethamine was observed at 15 minutes in two patients (3009 and 2916 picograms/mL), at 30 minutes in two patients (3097 and 2792 picograms/mL), and at 60 minutes in one patient (2718 picograms/mL). (nih.gov)

Fever1

• Fever is a common side effect of carboprost. (picmonic.com)

Asthma1

• Given that carboprost and intravenous (IV) labetalol may be associated with asthma exacerbation, adjusted models for receipt of these medications were created with adjusted risk ratios with 95% CIs as measures of effect. (nih.gov)

Smooth muscle1

• Carboprost tromethamine also stimulates the smooth muscle of the human gastrointestinal tract. (nih.gov)

Side effects2

• Serious side effects have been reported with carboprost. (rxwiki.com)
• This is not a complete list of carboprost side effects. (rxwiki.com)

Drug1

• Carboprost is supplied with its salt derivative tromethamine in 1 milliliter ampules containing a 250 microgram/milliliter solution of the active drug. (mdwiki.org)

Treatment1

• Peripheral blood samples were collected at several times during the four hours following treatment and carboprost tromethamine levels were determined by radioimmunoassay. (nih.gov)

Status1

• Risk for status asthmaticus based on receipt of carboprost and IV labetalol was analyzed. (nih.gov)