A nonsteroidal abortifacient agent that is effective in both the first and second trimesters of PREGNANCY.
Organized services to provide information on any questions an individual might have using databases and other sources. (From Random House Unabridged Dictionary, 2d ed)
A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.
Organized activities related to the storage, location, search, and retrieval of information.
The time it takes for a substance (drug, radioactive nuclide, or other) to lose half of its pharmacologic, physiologic, or radiologic activity.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
An effect usually, but not necessarily, beneficial that is attributable to an expectation that the regimen will have an effect, i.e., the effect is due to the power of suggestion.
The shortest and widest portion of the SMALL INTESTINE adjacent to the PYLORUS of the STOMACH. It is named for having the length equal to about the width of 12 fingers.
The attachment of PLATELETS to one another. This clumping together can be induced by a number of agents (e.g., THROMBIN; COLLAGEN) and is part of the mechanism leading to the formation of a THROMBUS.
Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.

Effects of endothelin on porcine coronary arterial strips. (1/4)

Endothelin, a novel endothelium derived 21-residue vasoconstrictor peptide synthesized by Peninsula Laboratories, provoked a concentration-dependent contraction of porcine coronary arterial strips. EC50 value for endothelin was 14 +/- SD 4 nmol/L (n = 6), and significantly lower than the values for 5-hydroxytryptamine (5-HT, 0.28 +/- 0.07 mumol/L, n = 6) and 15-methyl-prostaglandin F2 alpha (15-methyl-PGF2 alpha, 4 +/- 3 mumol/L, n = 7). The maximal increase in tension caused by endothelin was 5.4 +/- 1.1 g, being much greater than that induced by 5-HT (3.7 +/- 0.8 g, P less than 0.05) and 15-methyl-PGF2 alpha (3.7 +/- 0.6 g, P less than 0.01). The changes in tension provoked by endothelin (2-20 nmol/L) were attenuated significantly after pretreated with tetrodotoxin (TTX, 30 mumol/L, P less than 0.05 or 0.01). The results suggest that endothelin is one of the most potent vasoconstrictive agents, and its action is partially related to voltage-sensitive Na+ channel in the cell membrane.  (+info)

The contributions of adrenal hormones, hemodynamic factors, and the endotoxin-related stress reaction to stable prostaglandin analog-induced peripheral lymphopenia and neutrophilia. (2/4)

Stable prostaglandin analogs are known to induce lymphopenia and neutrophilia in a dose-dependent fashion after subcutaneous injection in rats. The purpose of the present investigation is to determine whether the prostaglandin-induced changes in circulating leukocytes might be secondary to hypotension with the ensuing release of adrenal hormones. The adrenal medullary catecholamine epinephrine was found to induce neutrophilia in both intact and adrenalectomized rats, and the glucocorticosteroid analog dexamethasone induced a profound lymphopenia in rats as reported by previous investigators. A stable analog of PGF2 alpha (15-S-15-methyl PGF2 alpha; M-PGF2 alpha) at the dose of 1 mg/kg induced marked systemic hypotension 1 h after injection, with lymphopenia and neutrophilia 6 h after injection. The non-prostanoid hypotensive agent captopril, at a dose of 63 mg/kg, induced a hypotension of similar magnitude and kinetics to that induced by prostaglandin. Captopril also induced lymphopenia and neutrophilia at 6 h, although the neutrophilia was of lesser magnitude than that induced by prostaglandins. The prostaglandin-induced lymphopenia was found to be mediated, at least in part, by the hypotension-induced release of adrenal hormones, as evidenced by the abrogation of lymphopenia in prostaglandin-treated adrenalectomized rats. Captopril-treated adrenalectomized rats, however, did develop a significant lymphopenia, suggesting that hypotension can result in lymphopenia even in adrenalectomized rats. The M-PGF2 alpha-induced neutrophilia in adrenalectomized rats, by comparison to captopril-induced neutrophilia in adrenalectomized rats, was greater than the neutrophilia expected as the result of hypotension alone. Indeed, the M-PGF2 alpha-induced neutrophilia in adrenalectomized rats was greater than the captopril-induced neutrophilia in sham-adrenalectomized rats. Thus, a portion of the neutrophilia induced by M-PGF2 alpha in intact rats may be mediated through adrenal-independent, hemodynamic-independent mechanisms. The possibility that M-PGF2 alpha might be inducing neutrophilia via an endotoxin-like stress reaction was investigated by examining changes in circulating white blood cells in intact and adrenalectomized C3H/HeN (endotoxin-sensitive) and C3H/HeJ (endotoxin-resistant) mice after prostaglandin administration. No quantitative differences in the prostaglandin-induced neutrophilia were noted in C3H/HeJ mice as compared to the C3H/HeN mice.(ABSTRACT TRUNCATED AT 400 WORDS)  (+info)

Stable analogs of prostaglandins E1 and F2 alpha ameliorate the proteinuria of aminonucleoside-of-puromycin nephrosis in Lewis rats. (3/4)

Prostaglandins have been implicated by previous investigators in the pathogenesis of the nephrotic syndrome. A single subcutaneous injection of 1 mg/kg of stable analogs of prostaglandins E1 or F2 alpha (15[S]-15-methyl -PGE1 [M-PGE1] and -PGF2 alpha [M-PGF2 alpha]) was found in the present study to dramatically decrease proteinuria on Day 10 of puromycin aminonucleoside (PAN) nephrosis in Lewis rats. The decrease in proteinuria was mediated at least in part by a decrease in glomerular filtration rate (GFR), as quantitated by inulin clearances in nephrotic control and prostaglandin-treated rats. M-PGE1, moderately, and M-PGF2 alpha, to a lesser degree, also decreased the GFR in normal rats. Interestingly, the GFR was dramatically decreased in nephrotic as compared with nonnephrotic control rats, which suggests that PAN nephrosis may not be an ideal experimental model for human minimal change nephrosis in which the GFR is usually not severely compromised. The prostaglandin-induced decrease in GFR in both nephrotic and normal rats was coincident with a drop in systemic blood pressure. Nephrotic rats, however, had a slightly higher baseline blood pressure than normals, and the hypotensive effects of both prostaglandins were much less in nephrotic than in normal rats. The decrease in proteinuria was not related to a cytoprotective effect, as indicated by the failure of daily doses of 5 micrograms/kg M-PGE1 to reduce proteinuria 6, 8, or 10 days after injection of puromycin aminonucleoside. The similar antiproteinuric effects of prostaglandin synthesis inhibitors and of pharmacologic doses of prostaglandins are somewhat paradoxical but are reminiscent of the similarly paradoxical mutual antiinflammatory effects of these agents. The high doses of prostaglandins required to reduce proteinuria as well as their reduction of blood pressure and GFR will limit their clinical usefulness in the nephrotic syndrome.  (+info)

Effects of endothelin-1 on isolated uterine horns in estrogen-primed and pregnant mice. (4/4)

Mouse uterine horns from 4 states (estrogen-primed and early-, mid-, and late-pregnancy) were used to study the effect of endothelin-1 (ET) vs carboprost (Car) and oxytocin (Oxy). In K(+)-Krebs (KCl 40 mmol.L-1) solution, ET (1-300 nmol.L-1), Car (0.002-20 mumol.L-1), and Oxy (0.6-60 nmol.L-1) evoked concentration-dependent increases in tension of the uterine horns from 4 different states. Emax for ET were 1.12 +/- 0.26, 1.27 +/- 0.18, and 1.49 +/- 0.13 g in early-, mid-, and late-pregnancies, respectively. Emax for Car in mid- was twice that in late-pregnancy, whereas Emax for Oxy in late- was thrice that in mid-pregnancy. EC50 for ET were 9.6, 5.8, and 6.3 nmol.L-1 in early-, mid-, and late-pregnancies, respectively, and were only 2% to 7% of that for Car and 3-15 times of that for Oxy in various gravid stages. The results suggest that the contractile activity of pregnant mouse uterus to ET is more potent than that of Car while slightly weaker than that of Oxy.  (+info)

Carboprost is a synthetic analogue of prostaglandin F2α, which is a naturally occurring hormone-like substance in the body. It is primarily used as a medical treatment to induce labor or to manage postpartum hemorrhage (severe bleeding after childbirth) due to uterine atony (failure of the uterus to contract).

Carboprost works by causing strong contractions of the uterus, which can help to promote labor or reduce excessive bleeding. It is administered intramuscularly (injected into a muscle) and its effects are usually seen within a few minutes after injection. Common side effects include nausea, vomiting, diarrhea, and fever.

It's important to note that Carboprost should only be used under the supervision of a healthcare professional, as it can have serious side effects if not used properly.

In the context of healthcare, "Information Services" typically refers to the department or system within a healthcare organization that is responsible for managing and providing various forms of information to support clinical, administrative, and research functions. This can include:

1. Clinical Information Systems: These are electronic systems that help clinicians manage and access patient health information, such as electronic health records (EHRs), computerized physician order entry (CPOE) systems, and clinical decision support systems.

2. Administrative Information Systems: These are electronic systems used to manage administrative tasks, such as scheduling appointments, billing, and maintaining patient registries.

3. Research Information Services: These provide support for research activities, including data management, analysis, and reporting. They may also include bioinformatics services that deal with the collection, storage, analysis, and dissemination of genomic and proteomic data.

4. Health Information Exchange (HIE): This is a system or service that enables the sharing of clinical information between different healthcare organizations and providers.

5. Telemedicine Services: These allow remote diagnosis and treatment of patients using telecommunications technology.

6. Patient Portals: Secure online websites that give patients convenient, 24-hour access to their personal health information.

7. Data Analytics: The process of examining data sets to draw conclusions about the information they contain, often with the intention of predicting future trends or behaviors.

8. Knowledge Management: The process of identifying, capturing, organizing, storing, and sharing information and expertise within an organization.

The primary goal of healthcare Information Services is to improve the quality, safety, efficiency, and effectiveness of patient care by providing timely, accurate, and relevant information to the right people in the right format.

I'm sorry for any confusion, but "Internet" is a term that pertains to the global network of interconnected computers and servers that enable the transmission and reception of data via the internet protocol (IP). It is not a medical term and does not have a specific medical definition. If you have any questions related to medicine or health, I'd be happy to try to help answer them for you!

'Information Storage and Retrieval' in the context of medical informatics refers to the processes and systems used for the recording, storing, organizing, protecting, and retrieving electronic health information (e.g., patient records, clinical data, medical images) for various purposes such as diagnosis, treatment planning, research, and education. This may involve the use of electronic health record (EHR) systems, databases, data warehouses, and other digital technologies that enable healthcare providers to access and share accurate, up-to-date, and relevant information about a patient's health status, medical history, and care plan. The goal is to improve the quality, safety, efficiency, and coordination of healthcare delivery by providing timely and evidence-based information to support clinical decision-making and patient engagement.

In the context of pharmacology, "half-life" refers to the time it takes for the concentration or amount of a drug in the body to be reduced by half during its elimination phase. This is typically influenced by factors such as metabolism and excretion rates of the drug. It's a key factor in determining dosage intervals and therapeutic effectiveness of medications, as well as potential side effects or toxicity risks.

An encyclopedia is a comprehensive reference work containing articles on various topics, usually arranged in alphabetical order. In the context of medicine, a medical encyclopedia is a collection of articles that provide information about a wide range of medical topics, including diseases and conditions, treatments, tests, procedures, and anatomy and physiology. Medical encyclopedias may be published in print or electronic formats and are often used as a starting point for researching medical topics. They can provide reliable and accurate information on medical subjects, making them useful resources for healthcare professionals, students, and patients alike. Some well-known examples of medical encyclopedias include the Merck Manual and the Stedman's Medical Dictionary.

Platelet aggregation inhibitors are a class of medications that prevent platelets (small blood cells involved in clotting) from sticking together and forming a clot. These drugs work by interfering with the ability of platelets to adhere to each other and to the damaged vessel wall, thereby reducing the risk of thrombosis (blood clot formation).

Platelet aggregation inhibitors are often prescribed for people who have an increased risk of developing blood clots due to various medical conditions such as atrial fibrillation, coronary artery disease, peripheral artery disease, stroke, or a history of heart attack. They may also be used in patients undergoing certain medical procedures, such as angioplasty and stenting, to prevent blood clot formation in the stents.

Examples of platelet aggregation inhibitors include:

1. Aspirin: A nonsteroidal anti-inflammatory drug (NSAID) that irreversibly inhibits the enzyme cyclooxygenase, which is involved in platelet activation and aggregation.
2. Clopidogrel (Plavix): A P2Y12 receptor antagonist that selectively blocks ADP-induced platelet activation and aggregation.
3. Prasugrel (Effient): A third-generation thienopyridine P2Y12 receptor antagonist, similar to clopidogrel but with faster onset and greater potency.
4. Ticagrelor (Brilinta): A direct-acting P2Y12 receptor antagonist that does not require metabolic activation and has a reversible binding profile.
5. Dipyridamole (Persantine): An antiplatelet agent that inhibits platelet aggregation by increasing cyclic adenosine monophosphate (cAMP) levels in platelets, which leads to decreased platelet reactivity.
6. Iloprost (Ventavis): A prostacyclin analogue that inhibits platelet aggregation and causes vasodilation, often used in the treatment of pulmonary arterial hypertension.
7. Cilostazol (Pletal): A phosphodiesterase III inhibitor that increases cAMP levels in platelets, leading to decreased platelet activation and aggregation, as well as vasodilation.
8. Ticlopidine (Ticlid): An older P2Y12 receptor antagonist with a slower onset of action and more frequent side effects compared to clopidogrel or prasugrel.

Aspirin is the common name for acetylsalicylic acid, which is a medication used to relieve pain, reduce inflammation, and lower fever. It works by inhibiting the activity of an enzyme called cyclooxygenase (COX), which is involved in the production of prostaglandins, hormone-like substances that cause inflammation and pain. Aspirin also has an antiplatelet effect, which means it can help prevent blood clots from forming. This makes it useful for preventing heart attacks and strokes.

Aspirin is available over-the-counter in various forms, including tablets, capsules, and chewable tablets. It is also available in prescription strengths for certain medical conditions. As with any medication, aspirin should be taken as directed by a healthcare provider, and its use should be avoided in children and teenagers with viral infections due to the risk of Reye's syndrome, a rare but serious condition that can affect the liver and brain.

The placebo effect is a psychological or psychophysiological phenomenon in which a person's symptoms improve following a treatment but this improvement is not attributable to the properties of the treatment itself. Instead, it is believed to be due to the mind's belief in the effectiveness of the treatment, often influenced by positive expectations and the ritualistic aspects of the therapy itself.

Placebos are often used in clinical trials as a control group to compare against the actual treatment. The placebo effect can make it challenging to determine whether an observed improvement is truly due to the treatment or other factors.

The duodenum is the first part of the small intestine, immediately following the stomach. It is a C-shaped structure that is about 10-12 inches long and is responsible for continuing the digestion process that begins in the stomach. The duodenum receives partially digested food from the stomach through the pyloric valve and mixes it with digestive enzymes and bile produced by the pancreas and liver, respectively. These enzymes help break down proteins, fats, and carbohydrates into smaller molecules, allowing for efficient absorption in the remaining sections of the small intestine.

Platelet aggregation is the clumping together of platelets (thrombocytes) in the blood, which is an essential step in the process of hemostasis (the stopping of bleeding) after injury to a blood vessel. When the inner lining of a blood vessel is damaged, exposure of subendothelial collagen and tissue factor triggers platelet activation. Activated platelets change shape, become sticky, and release the contents of their granules, which include ADP (adenosine diphosphate).

ADP then acts as a chemical mediator to attract and bind additional platelets to the site of injury, leading to platelet aggregation. This forms a plug that seals the damaged vessel and prevents further blood loss. Platelet aggregation is also a crucial component in the formation of blood clots (thrombosis) within blood vessels, which can have pathological consequences such as heart attacks and strokes if they obstruct blood flow to vital organs.

Coronary artery bypass surgery, also known as coronary artery bypass grafting (CABG), is a surgical procedure used to improve blood flow to the heart in patients with severe coronary artery disease. This condition occurs when the coronary arteries, which supply oxygen-rich blood to the heart muscle, become narrowed or blocked due to the buildup of fatty deposits, called plaques.

During CABG surgery, a healthy blood vessel from another part of the body is grafted, or attached, to the coronary artery, creating a new pathway for oxygen-rich blood to flow around the blocked or narrowed portion of the artery and reach the heart muscle. This bypass helps to restore normal blood flow and reduce the risk of angina (chest pain), shortness of breath, and other symptoms associated with coronary artery disease.

There are different types of CABG surgery, including traditional on-pump CABG, off-pump CABG, and minimally invasive CABG. The choice of procedure depends on various factors, such as the patient's overall health, the number and location of blocked arteries, and the presence of other medical conditions.

It is important to note that while CABG surgery can significantly improve symptoms and quality of life in patients with severe coronary artery disease, it does not cure the underlying condition. Lifestyle modifications, such as regular exercise, a healthy diet, smoking cessation, and medication therapy, are essential for long-term management and prevention of further progression of the disease.

... at the U.S. National Library of Medicine Medical Subject Headings (MeSH) v t e (Articles with short description, ... Carboprost (INN, trade names for the tromethamine salts Hemabate, Tham) is a synthetic prostaglandin analogue of PGF2α ( ... Carboprost is also used for the termination of pregnancy in the 2nd trimester. Contraindicated in severe cardiovascular, renal ... Carboprost's main use is in the obstetrical emergency of postpartum hemorrhage which reduces postpartum bleeding during these ...
Carboprost: an analogue of PGF 2α, this prostaglandin contains oxytocic properties that permit a longer duration of action than ... Vallera C, Choi LO, Cha CM, Hong RW (June 2017). "Uterotonic Medications: Oxytocin, Methylergonovine, Carboprost, Misoprostol ...
15-methyl-PGF2-alpha (Hemabate, Carboprost) Highly effective but it is expensive. It can cause bronchospasm and it should be ...
The following medications are analogues of prostaglandin F2α: Latanoprost Bimatoprost Travoprost Carboprost O'Neil MJ, ed. ( ... Prostaglandin F2α (PGF2α in prostanoid nomenclature), pharmaceutically termed carboprost is a naturally occurring prostaglandin ...
Some medications are formulated as the "tromethamine salt" including Hemabate (carboprost as trometamol salt), and "ketorolac ...
... carboprost tromethamine), consider: uterine artery embolization, dilatation and curettage, and laparotomy with uterine ...
... carboprost MeSH D10.251.355.255.550.700.500.175 - cloprostenol MeSH D10.251.355.255.775 - thromboxanes MeSH D10.251.355.310 - ...
... another surname Carboprost This page lists people with the surname Tham. If an internal link intending to refer to a specific ...
... carboprost (INN) Carboptic carboquone (INN) carbromal (INN) carbubarb (INN) carburazepam (INN) carbutamide (INN) carbuterol ( ...
... and oxytocin QG02AC90 Ergometrine and oxytocin G02AD01 Dinoprost G02AD02 Dinoprostone G02AD03 Gemeprost G02AD04 Carboprost ...
The molecular formula C21H36O5 (molar mass: 368.51 g/mol, exact mass: 368.2563 u) may refer to: Betaenone B Carboprost This set ...
... carboprost MeSH D23.469.700.670.175 - cloprostenol MeSH D23.767.193.184 - bilirubin MeSH D23.767.193.184.200 - biliverdine MeSH ...
Carboprost at the U.S. National Library of Medicine Medical Subject Headings (MeSH) v t e (Articles with short description, ... Carboprost (INN, trade names for the tromethamine salts Hemabate, Tham) is a synthetic prostaglandin analogue of PGF2α ( ... Carboprost is also used for the termination of pregnancy in the 2nd trimester. Contraindicated in severe cardiovascular, renal ... Carboprosts main use is in the obstetrical emergency of postpartum hemorrhage which reduces postpartum bleeding during these ...
Check with your doctor as soon as possible if any of the following side effects occur:. Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:. ...
Toxicity. It cannot be excluded that carboprost is toxic, due to the lack of data. ... This summary information comes from Fass Prostinfenem (carboprost) from Pfizer (2023-06-28). It is voluntary for manufacturers ... Bioaccumulation. It cannot be excluded that carboprost bioaccumulates, due to the lack of data. ...
Get up-to-date information on Carboprost side effects, uses, dosage, overdose, pregnancy, alcohol and more. Learn more about ... Carboprost is used to abort pregnancy between weeks 13 and 20. Carboprost is also used to stop bleeding after giving birth. ... Carboprost is a prescription medication used to abort pregnancy as well as stop bleeding after giving birth. Carboprost belongs ... How was your experience with Carboprost?. First, a little about yourself. Male Female ...
Find information on Carboprost (Hemabate) in Daviss Drug Guide including dosage, side effects, interactions, nursing ... www.drugguide.com/ddo/view/Davis-Drug-Guide/51130/all/carboprost. Vallerand AHA, Sanoski CAC, Quiring CC. Carboprost. Daviss ... Vallerand, A. H., Sanoski, C. A., & Quiring, C. (2023). Carboprost. In Daviss Drug Guide (18th ed.). F.A. Davis Company. https ... TY - ELEC T1 - carboprost ID - 51130 A1 - Sanoski,Cynthia A, AU - Vallerand,April Hazard, AU - Quiring,Courtney, BT - Daviss ...
Opulent Pharma is a Chemistry driven Research Organization specialised in key areas like synthetic organic chemistry, medicinal chemistry which offers Custom Synthesis & Chemical Development services of desired compounds from milligram to kg level ...
... exporter of Carboprost Tromethamine API Manufacturers, Latanoprost API in India, Hydroquinone Exporters, Benfotiamine API from ...
Prostaglandin 15-methyl F2 alpha (carboprost tromethamine, Hemabate; Pharmacia & Upjohn Company, Division of Pfizer, New York, ...
carboprost tromethamine. Monitor Closely (1)carboprost tromethamine increases effects of oxytocin by pharmacodynamic synergism ... carboprost tromethamine. carboprost tromethamine increases effects of oxytocin by pharmacodynamic synergism. Use Caution/ ...
carboprost tromethamine. Monitor Closely (1)eluxadoline increases levels of carboprost tromethamine by decreasing metabolism. ... carboprost tromethamine. eluxadoline increases levels of carboprost tromethamine by decreasing metabolism. Use Caution/Monitor ...
Study Pregnancy & Labour flashcards from Cameron MacFarlane's class online, or in Brainscape's iPhone or Android app. ✓ Learn faster with spaced repetition.
Aktuelle API Auditberichte • GMP-Audits der Herstelung pharmazeutischer Ausgangs- und Wirkstoffe nach ICH Q7 / EU GMP Guide Part II • Diapharm
... carboprost tromethamine (Hemabate), dinoprostone (Cervidil, Prepidil, Prostin E2), epoprostenol (Flolan, Veletri), latanoprost ...
R. Zhang, H. Shi, F. Ren, and Z. Yuan, "Assessment of carboprost tromethamine for reducing hemorrhage in laparoscopic ...
The first stop for professional medicines advice
Carboprost tromethamine. Prostaglandin E2 receptor EP1 subtype. target. Irinotecan. DNA topoisomerase I, mitochondrial. target ... Carboprost tromethamine. A prostaglandin used to treat postpartum uterine hemorrhage due to atony when other methods of ...
Intravesicular carboprost for the treatment of hemorrhagic cystitis after marrow transplantation. Urology. 1995 Dec. 46(6):811- ... Evaluation of carboprost tromethamine in the treatment of cyclophosphamide-induced hemorrhagic cystitis. Cancer. 1990 Jul 15. ... Carboprost is a prostaglandin that elicits cytoprotective, anti-inflammatory, and vasoconstrictive properties and produces no ... Persistent hematuria can be treated with bladder irrigation, using carboprost, 1-2% alum, or silver nitrate. If hemorrhagic ...
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... www.zionmarketresearch.com/report/carboprost-tromethamine-marketHigh Heat Melamine Foam Market: Global Industry Analysis, Size ...
Carboprost (Hemabate). Mechanism. Prostaglandin F2-alpha Analog. Smooth Muscle Contraction. Indications. Postpartum Hemorrhage ...
After the maternal request and ethical committee approval, feticide was performed followed by IA injection of carboprost 4 ml ... Objective: To compare results of intra-amniotic injection of carboprost (IA method) with mifepristone-misoprostol oral/vaginal ...
These medications include oxytocin (Pitocin®), misoprostol (Cytotec®), methylergonovine maleate (Methergine®,), carboprost ...
Mathieu P, Villemot JP, Stoltz JF, Scheck F, Garnier LF (June 1996). "[Antiaggregant effect and tolerance of calcium carbasalate administrated immediately after aorto-coronary bypass. Results of a double-blind versus placebo study]". Pathologie-Biologie. 44 (6): 571-80. PMID 8977914 ...
InChI=1S/C16H14O5/c1-11(17)20-13-8-4-3-7-12(13)16(18)21-15-10-6-5-9-14(15)19-2/h3-10H,1- ...
b. 5-Methoxy - 2-oxo-1,3-dioxol - 4 - yl ) methyl - 4 - (1-hydroxy -1 -methylethyl -2 propyl-1- (2 -(2-triphenylmethyl ) -2H - tetrazole -5 - yl ) biphenyl -4-yl ) methyl ) -1H-imidazole - 5 - ...
Carboprost. Carvedilol. Carvedilol Phosphate. Cetrizine Hydrochloride. Cefdinir. Cefixime Trihydrate. Cefrozil Monohydrate. ...
Carboprost 125mcg 30. ENDOPROST 250MG IN SS BHARAT SERUM LT VIAL. 185.00. 6.00. CARBOPROST 250MCG ...
The first stop for professional medicines advice
  • Carboprost (INN, trade names for the tromethamine salts Hemabate, Tham) is a synthetic prostaglandin analogue of PGF2α (specifically, it is 15-methyl-PGF2α) with oxytocic properties. (wikipedia.org)
  • When assessing a patient after the administration of carboprost (Hemabate), which side effect should the nurse expect? (floridiancecourses.org)
  • Carboprost is a prostaglandin that elicits cytoprotective, anti-inflammatory, and vasoconstrictive properties and produces no coagulum. (medscape.com)
  • The average peak concentrations of drug were slightly higher following each successive injection of the prostaglandin, but always decreased to levels less than the preceding peak values by two hours after each injection.Five women who had delivery spontaneously at term were treated immediately postpartum with single injection of 250 micrograms of carboprost tromethamine. (drugcentral.org)
  • One study has shown that carboprost tromethamine is more effective than oxytocin in preventing postpartum hemorrhage in high-risk patients undergoing cesarean delivery. (wikipedia.org)
  • carboprost tromethamine increases effects of oxytocin by pharmacodynamic synergism. (medscape.com)
  • Their research compared mothers given carboprost tromethamine (an oxytocin inducer) injections with this injection plus motherwort injections. (plantmedicines.org)
  • As uterus was flabby, intravenous (IV) oxytocin infusion 30 units was started and injection carboprost 0.25 mg intramuscular (IM) given. (emedinexus.com)
  • The adverse effects of carboprost tromethamine injection sterile solution are generally transient and reversible when therapy ends. (drugcentral.org)
  • Their use should be considered an integral part of the management of patients undergoing abortion with carboprost tromethamine injection.Of those patients experiencing temperature elevation, approximately one-sixteenth had clinical diagnosis of endometritis. (drugcentral.org)
  • Carboprost tromethamine injection sterile solution (carboprost tromethamine), like other potent oxytocic agents, should be used only with strict adherence to recommended dosages.Carboprost tromethamine injection should be used by medically trained personnel in hospital which can provide immediate intensive care and acute surgical facilities. (drugcentral.org)
  • Carcinogenic bioassay studies have not been conducted in animals with carboprost tromethamine injection due to the limited indications for use and short duration of administration. (drugcentral.org)
  • Aminophylline Injection IP 2.5% w/v (NLEM) Carboprost Promethamine Inj.USP 250 mg/ml Hydrocortisone sodium succinate for inj. (pdfdrug.com)
  • Hypersensitivity to carboprost or any of its components is also a contraindication asthma anemia jaundice diabetes mellitus seizure disorders past uterine surgery diarrhea (most common, may be sudden in onset) flushing or hot flashes fever chills nausea/vomiting Carboprost is supplied with its salt derivative tromethamine in 1 milliliter ampules containing a 250 microgram/milliliter solution of the active drug. (wikipedia.org)
  • The resulting mixture of tertiary carbinols (2) is transformed to oxytocic carboprost (3) by standard transformations, including separation of diastereomers, so that the final product is the C-15 analogue. (wikipedia.org)
  • Carboprost tromethamine should be used only with strict adherence to recommended dosages like other potent oxytocic agents. (rxwiki.com)
  • Carboprost is also used for the termination of pregnancy in the 2nd trimester. (wikipedia.org)
  • With the clinical doses of carboprost tromethamine used for the termination of pregnancy, and for use postpartum, some patients do experience transient temperature increases.In laboratory animals and in humans large doses of carboprost tromethamine can raise blood pressure, probably by contracting the vascular smooth muscle. (drugcentral.org)
  • With the clinical doses of carboprost tromethamine used for the termination of pregnancy, some patients do experience temperature increases. (drugcentral.org)
  • Carboprost tromethamine administered intramuscularly stimulates in the gravid uterus myometrial contractions similar to labor contractions at the end of full term pregnancy. (drugcentral.org)
  • Whether or not these contractions result from direct effect of carboprost on the myometrium has not been determined. (drugcentral.org)
  • Nonetheless, they evacuate the products of conception from the uterus in most cases.Postpartum, the resultant myometrial contractions provide hemostasis at the site of placentation.Carboprost tromethamine also stimulates the smooth muscle of the human gastrointestinal tract. (drugcentral.org)
  • This activity may produce the vomiting or diarrhea or both that is common when carboprost tromethamine is used to terminate pregnancy and for use postpartum. (drugcentral.org)
  • Your doctor may give you medications to help with nausea, vomiting, and diarrhea when being treated with carboprost. (rxwiki.com)
  • Common side effects of carboprost include vomiting, diarrhea, and nausea. (rxwiki.com)
  • Carboprost belongs to a group of drugs called prostaglandins. (rxwiki.com)
  • Carboprost is used to abort pregnancy and to stop bleeding after giving birth. (rxwiki.com)
  • Carboprost is used to abort pregnancy between weeks 13 and 20. (rxwiki.com)
  • With the doses of carboprost tromethamine used for terminating pregnancy, this effect has not been clinically significant. (drugcentral.org)
  • Serious side effects have been reported with carboprost. (rxwiki.com)
  • This is not a complete list of carboprost side effects. (rxwiki.com)
  • Peripheral blood samples were collected at several times during the four hours following treatment and carboprost tromethamine levels were determined by radioimmunoassay. (drugcentral.org)
  • What tips would you provide a friend before taking Carboprost? (rxwiki.com)
  • Carboprost tromethamine should be used by medically trained personnel in a hospital which can provide immediate intensive care and acute surgical facilities. (rxwiki.com)
  • In some patients, carboprost tromethamine may cause transient bronchoconstriction.Drug plasma concentrations were determined by radioimmunoassay in peripheral blood samples collected by different investigators from 10 patients undergoing abortion. (drugcentral.org)
  • The patients had been injected intramuscularly with 250 micrograms of carboprost at two hour intervals. (drugcentral.org)
  • This summary information comes from Fass Prostinfenem (carboprost) from Pfizer (2023-06-28). (janusinfo.se)
  • How was your experience with Carboprost? (rxwiki.com)
  • Carboprost belongs to a group of drugs called prostaglandins. (rxwiki.com)
  • In some patients, carboprost tromethamine may cause transient bronchoconstriction. (nih.gov)
  • Carboprost should be used with caution in patients with a history of high blood pressure. (picmonic.com)
  • Hypersensitivity to carboprost or any of its components is also a contraindication [5] Exert caution in asthmatic patients as carboprost may cause bronchospasm. (mdwiki.org)
  • Carboprost-REACH (Reach Pharmaceuticals Pty Ltd)". Therapeutic Goods Administration (TGA). (wikipedia.org)
  • Given that carboprost and intravenous (IV) labetalol may be associated with asthma exacerbation, adjusted models for receipt of these medications were created with adjusted risk ratios with 95% CIs as measures of effect. (nih.gov)
  • Carboprost tromethamine also stimulates the smooth muscle of the human gastrointestinal tract. (nih.gov)
  • In laboratory animals and in humans large doses of carboprost tromethamine can raise blood pressure, probably by contracting the vascular smooth muscle. (nih.gov)
  • Carboprost is supplied with its salt derivative tromethamine in 1 milliliter ampules containing a 250 microgram/milliliter solution of the active drug. (mdwiki.org)
  • Risk for status asthmaticus based on receipt of carboprost and IV labetalol was analyzed. (nih.gov)