Chemicals and Drugs
Carbodiimides
Carbodiimides

Hairpin-shaped DNA duplexes with disulfide bonds in sugar-phosphate backbone as potential DNA reagents for crosslinking with proteins. (1/267)

Convenient approaches were described to incorporate -OP(=O)O(-)-SS-O(-)(O=)PO- bridges in hairpin-shaped DNA duplexes instead of regular phosphodiester linkages: (i) H2O2- or 2,2'-dipyridyldisulfide-mediated coupling of 3'- and 5'-thiophosphorylated oligonucleotides on complementary template and (ii) more selective template-guided autoligation of a preactivated oligonucleotide derivative with an oligomer carrying a terminal thiophosphoryl group. Dithiothreitol was found to cleave completely modified internucleotide linkage releasing starting oligonucleotides. The presence of complementary template as an intrinsic element of the molecule protects the hairpin DNA analog from spontaneous exchange of disulfide-linked oligomer fragments and makes it a good candidate for auto-crosslinking with cysteine-containing proteins.  (+info)

The effect of carboxyl group modification on the chromophore regeneration of archaeopsin-1 and bacterioopsin. (2/267)

Carboxyl group modification with DCCD and NCD-4 was employed to investigate the chemical environment of the side chains of archaeopsin-1 (aO-1) and bacterioopsin (bO). Some differences were observed between aO-1 and bO. Although DCCD or NCD-4 did not modify aO-1 in bleached membrane, they modified bO in bleached membrane and in mixed DMPC/CHAPS/SDS micelles at neutral pH, thereby affecting the opsin shift and the photocycle of the regenerated chromophore. On the contrary, after solubilization with SDS, aO-1 and bO were modified by DCCD and NCD-4, which decreased the chromophore regeneration. In particular, the reaction of aO-1 in SDS with NCD-4 proceeded in a 1:1 ratio at neutral pH. The fluorescence and CD spectra indicated that the modified site was located in the hydrophobic, asymmetrical region. Lysyl-endopeptidase digestion of NCD-4 modified aO-1 produced a fluorescent fragment and amino acid sequence analysis showed that Asp85 or Asp96 in helix C is a probable candidate for the modified residue at present. Kinetic CD measurements revealed that the introduction of N-acylurea at an Asp residue in helix C did not affect the formation of the transient intermediate but inhibited the side chain packing during refolding.  (+info)

Active site characterization of RNase Rs from Rhizopus stolonifer: involvement of histidine and lysine in catalysis and carboxylate in substrate binding. (3/267)

Chemical modification studies on purified RNase Rs revealed the involvement of a single histidine, lysine and carboxylate residue in the catalytic activity of the enzyme. RNA could not protect the enzyme against DEP- and TNBS-mediated inactivation whereas, substrate protection was observed in case of EDAC-mediated inactivation of the enzyme. K(m) and k(cat) values of the partially inactivated enzyme samples suggested that while histidine and lysine are involved in catalysis, carboxylate is involved in substrate binding. Active site nature of RNase Rs suggests that the inability of the enzyme to readily convert 2',3'-cyclic nucleotides to 3'-mononucleotides is probably due to the absence of catalytically active second histidine residue.  (+info)

Structural and kinetic studies of the pyruvate-ferredoxin oxidoreductase/ferredoxin complex from Desulfovibrio africanus. (4/267)

The pyruvate-ferredoxin oxidoreductase (PFOR)/ferredoxin (Fd) system of Desulfovibrio africanus has been investigated with the aim of understanding more fully protein-protein interaction and the kinetic characteristics of electron transfer between the two redox partners. D. africanus contains three Fds (Fd I, Fd II and Fd III) able to function as electron acceptors for PFOR. The complete amino acid sequence of Fd II was determined by automatic Edman degradation. It revealed a striking similarity to that of Fd I. The protein consists of 64 residues and its amino acid sequence is in agreement with a molecular mass of 6822.5 Da as measured by electrospray MS. Fd II contains five cysteine residues of which the first four (Cys11, Cys14, Cys17 and Cys54) are likely ligands for the single [4Fe-4S] cluster. A covalently cross-linked complex between PFOR and Fd I or Fd II was obtained by using a water soluble carbodiimide. This complex exhibited a stoichiometry of one ferredoxin for one PFOR subunit and is dependent on the ionic strength. The second-order rate constants for electron transfer between PFOR and Fds determined electrochemically using cyclic voltammetry are 7 x 107 M-1.s-1 for Fd I and 2 x 107 M-1.s-1 for Fd II and Fd III. The Km values of PFOR for Fd I and Fd II measured both by the electrochemical and the spectrophotometric method have been found to be 3 microM and 5 microM, respectively. The three-dimensional modelling of Fd II and surface analysis of Fd I, Fd II and PFOR suggest that a protein-protein complex is likely to be formed between aspartic acid/glutamic acid invariant residues of Fds and lysine residues surrounding the distal [4Fe-4S] cluster of PFOR. All of these studies are indicative of the involvement of electrostatic interactions between the two redox partners.  (+info)

S-layer-coated liposomes as a versatile system for entrapping and binding target molecules. (5/267)

In the present study, unilamellar liposomes coated with the crystalline bacterial cell surface layer (S-layer) protein of Bacillus stearothermophilus PV72/p2 were used as matrix for defined binding of functional molecules via the avidin- or streptavidin-biotin bridge. The liposomes were composed of dipalmitoyl phosphatidylcholine, cholesterol and hexadecylamine in a molar ratio of 10:5:4 and they had an average size of 180 nm. For introducing specific functions into the S-layer lattice without affecting substances encapsulated within the liposomes, crosslinking and activation reagents had to be identified which did not penetrate the liposomal membrane. Among different reagents, a hydrophilic dialdehyde generated by periodate cleavage of raffinose and a sulfo-succinimide activated dicarboxylic acid were found to be impermeable for the liposomal membrane. Both reagents completely crosslinked the S-layer lattice without interfering with its regular structure. Biotinylation of S-layer-coated liposomes was achieved by coupling p-diazobenzoyl biocytin which preferably reacts with the phenolic residue of tyrosine or with the imidazole ring of histidine. By applying this method, two biotin residues accessible for subsequent avidin binding were introduced per S-layer subunit. As visualized by labeling with biotinylated ferritin, an ordered monomolecular layer of streptavidin was formed on the surface of the S-layer-coated liposomes. As a second model system, biotinylated anti-human IgG was attached via the streptavidin bridge to the biotinylated S-layer-coated liposomes. The biological activity of the bound anti-human IgG was confirmed by ELISA.  (+info)

An essential glutamyl residue in EmrE, a multidrug antiporter from Escherichia coli. (6/267)

EmrE is an Escherichia coli 12-kDa protein that confers resistance to toxic compounds, by actively removing them in exchange with protons. The protein includes eight charged residues. Seven of these residues are located in the hydrophilic loops and can be replaced with either Cys or another amino acid bearing the same charge, without impairing transport activity. Glu-14 is the only charged residue in the membrane domain and is conserved in all the proteins of the family. We show here that this residue is the site of action of dicyclohexylcarbodiimide, a carbodiimide known to act in hydrophobic environments. When Glu-14 was replaced with either Cys or Asp, resistance was abolished. Whereas the E14C mutant displays no transport activity, the E14D protein shows efflux and exchange at rates about 30-50% that of the wild type. The maximal DeltapH-driven uptake rate of E14D is only 10% that of the wild type. The mutant shows a different pH profile in all the transport modes. Our results support the notion that Glu-14 is an essential part of a binding domain shared by substrates and protons but mutually exclusive in time. This notion provides the molecular basis for the obligatory exchange catalyzed by EmrE.  (+info)

Identification and characterization of a novel cAMP receptor protein in the cyanobacterium Synechocystis sp. PCC 6803. (7/267)

Three open reading frames of Synechocystis sp. PCC 6803 encoding a domain homologous with the cAMP binding domain of bacterial cAMP receptor protein were analyzed. These three open reading frames, sll1371, sll1924, and slr0593, which were named sycrp1, sycrp2, and sypk, respectively, were expressed in Escherichia coli as His-tagged or glutathione S-transferase fusion proteins and purified, and their biochemical properties were investigated. The results obtained for equilibrium dialysis measurements using these recombinant proteins suggest that SYCRP1 and SYPK show a binding affinity for cAMP while SYCRP2 does not. The dissociation constant of His-tagged SYCRP1 for cAMP is approximately 3 microM. A cross-linking experiment using 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide revealed that His-tagged SYCRP1 forms a homodimer, and the presence or absence of cAMP does not affect the formation of the homodimer. The amino acid sequence reveals that SYCRP1 has a domain similar to the DNA binding domain of bacterial cAMP receptor protein in the COOH-terminal region. Consistent with this, His-tagged SYCRP1 forms a complex with DNA that contains the consensus sequence for E. coli cAMP receptor protein in the presence of cAMP. These results strongly suggest that SYCRP1 is a novel cAMP receptor protein.  (+info)

Comparison of the efficiency of various coupling systems in the acylation of model secondary amines with thymin-1-ylacetic acid. (8/267)

Peptide nucleic acids (PNAs) make a promising group of DNA analogues. The backbone of typical PNA oligomers is composed of N-(2-aminoethyl)glycine units, linked by the peptide bonds. The backbone secondary amine groups are acylated with carboxyalkyl derivatives of nucleobases. One of the PNA synthesis step causing some problems is the acylation of the monomer backbone with the nucleobase derivatives. The aim of the study was to compare the efficiency of various coupling systems in the acylation. Simple model compounds (piperidine and proline) were used, as well as equimolar amounts of the coupling reagents. Selected systems based on carbodiimides, aminium or phosphonium salts, mixed anhydride, and active esters were tested.  (+info)

Patent US3632620 - Preparation of isocyanates from carbodiimides - Google PatentsPatent US3632620 - Preparation of isocyanates from carbodiimides - Google Patents
United States Patent 3,632,620 PREPARATION OF ISOCYANATES FROM CARBODIHVIIDES Ehrenfried H. Kober, Hamden, and Wilhelm J. Schnabel, Branford, C0nn., assignors to Olin Mathieson Chemical Corporation No Drawing. Filed June 26, 1968, Ser. No. 740,064 Int. Cl. C07c 119/04 US. Cl. 260-453 P 4 Claims ABSTRACT OF THE DISCLOSURE Organic carbodiimides are reacted with carbon monoxide and/or carbon dioxide in the presence of a catalyst at an elevated pressure and elevated temperature to produce organic isocyanates. The catalyst is preferably at least one metal or compound of a metal found in Groups Ib, IIb, IIIb, IVa, IVb, Va, VIa, VIb, Illa, VIIa, VIII, and in the Lanthanide series of the Periodic Table. This invention relates to the preparation of organic isocyanates from organic carbodiimides. Organic isocyanates are used extensively in the preparation of urethane foams, coatings, and fibers, as well as in the preparation of insecticides, pesticides and the like. Commercial processes for preparing ...
http://www.google.com/patents/US3632620?dq=6,332,126
Preparation of chemically modified transferrin proteins and an investigation of their reactions with DNA and other nucleic...
The molecular biology of human genetic disorders is under intensive investigation at present. In those cases where the disorder is clearly defined in terms of altered gene structure, possibilities may exist for the correction of the disorder by insertion of normal genes through the process of DNA transfection. A possible method for the transfer of genetic material is by attempting to attach DNA to a protein which has specific receptors on cells and which undergoes receptor-mediated endocytosis. By this means one might be able to get DNA into cells. This thesis deals with experimental work on the chemical modification of human serum transferrin by means of water-soluble carbodiimides. The resulting N-acylurea transferrins bind DNA in a reversible manner. Characteristics and properties of the binding interactions are dealt with in detail. N-acylurea derivatives of transferrin were prepared with the water-soluble carbodiimides, N-ethyl-N -(3-dimethylaminopropyl) carbodiimide and N-ethyl-N ...
https://researchspace.ukzn.ac.za/handle/10413/10098
2013-2010 - 叶德举课题组
30. Dengyou Zhang, Deju Ye, Enguang Feng, Jinfang Wang, Jianmei Shi, Hualiang Jiang, and Hong Liu. Highly alpha-Selective Synthesis of Sialyl Spirohydantoins by Regiospecific Domino Condensation/O®N Acyl Migration/N-Sialylation of Carbodiimides with Peracetylated Sialic Acid. J. Org. Chem. 2010, 75, 3552-3557.. 29. Lei Zhang, Deju Ye, Yu Zhou, Guannan Liu, Enguang Feng, Hualiang Jiang, and Hong Liu. Regioselective Synthesis of 3-Benzazepinones and Unexpected 5-Bromo-3-benzazepinones. J. Org. Chem. 2010, 75, 3671-3677.. 28. Xu Zhang, Yu Zhou, Hengshuai Wang, Diliang Guo, Deju Ye, Yungen Xu, Hualiang, Jiang, and Hong Liu. Silver-catalyzed intramolecular hydroamination of alkynes in aqueous media: efficient and regioselective synthesis for fused benzimidazoles. Green Chem. 2011, 13, 397-405.. 27. Deju Ye, Jinfang Wang, Dengyou Deng, Enguang Feng, Hualiang Jiang, and Hong Liu. Advances in O-Sialylation. Progress in Chemistry 2010, 22, 91-100.. 26. Xu Zhang, Yu Zhou, Hengshuai Wang, Diliang Guo, ...
http://hysz.nju.edu.cn/yedeju/Data/List/2013-2010
A surprising double carbon-nitrogen coupling reaction catalyzed by [H3Ru4 (C6H6)4 (OH)] 2+ : synthesis of unusual barbiturate...A surprising double carbon-nitrogen coupling reaction catalyzed by [H3Ru4 (C6H6)4 (OH)] 2+ : synthesis of unusual barbiturate...
Seven- and eight-membered analogues of barbituric acid are easily accessible by insertion of carbodiimides into cyclic anhydrides catalyzed by the cationic hydroxo cluster [H|sub|3|/sub|Ru|sub|4|/sub| (C|sub|6|/sub|H|sub|6|/sub|)|sub|4|/sub| (OH)] |sup|2+|/sup|. Chérioux, Frédéric; Süss-Fink, Georg
https://doc.rero.ch/record/5607?ln=de
DSPE-PEG(2000) Carboxylic Acid - Doxosome: Doxorubicin liposomesDoxosome: Doxorubicin liposomes
Carboxyl groups on the phospholipid can be activated by using water soluble carbodiimide reagents like EDC. Including sulfo-NHS in the reaction mixture generates ester derivatives that couple more efficiently than does EDC intermediate alone. These reactive ester intermediates can further be conjugated to amine on the antibody to form stable amide bond.. ...
http://doxosome.com/conjugation-through-n-terminus-of-antibody/carboxylic-acid-chemistry/dspe-peg2000-carboxylic-acid/
Succinyl PE - Doxosome: Doxorubicin liposomesDoxosome: Doxorubicin liposomes
Carboxyl groups on the phospholipid can be activated by using water soluble carbodiimide reagents like EDC. Including sulfo-NHS in the reaction mixture generates ester derivatives that couple more efficiently than does EDC intermediate alone. These reactive ester intermediates can further be conjugated to amine on the antibody to form stable amide bond.. ...
http://doxosome.com/conjugation-through-n-terminus-of-antibody/carboxylic-acid-chemistry/succinyl-pe/
Patente US4075194 - Novel synthetic undecapeptide and clinical assay - Google PatentesPatente US4075194 - Novel synthetic undecapeptide and clinical assay - Google Patentes
A novel synthetic peptide corresponding to the eleven amino acid residues of the NH2 -terminal portion in the sequence of carcinoembrionic antigen (CEA) has been synthesized and this was attached by means of a water-soluble carbodiimide reagent to multichain poly(DL)-alanine as well as to bovine serum albumin. The resulting macromolecular conjugates provoked rabbit anti- CEA(1-11) peptide antibodies and a novel assay was developed for ascertaining the presence of adenocarcinomas of the digestive tract, pancreas and breast, based on said novel compositions of matter.
http://www.google.es/patents/US4075194
Acetic acid, 2,4-dimethylpentyl esterAcetic acid, 2,4-dimethylpentyl ester
The National Institute of Standards and Technology (NIST) uses its best efforts to deliver a high quality copy of the Database and to verify that the data contained therein have been selected on the basis of sound scientific judgment. However, NIST makes no warranties to that effect, and NIST shall not be liable for any damage that may result from errors or omissions in the Database ...
http://webbook.nist.gov/cgi/inchi/InChI%3D1S/C9H18O2/c1-7
TDMS Study 93020-08 Pathology TablesTDMS Study 93020-08 Pathology Tables
NTP STATISTICAL ANALYSIS OF PRIMARY TUMORS REPORT: PEIRPT08 LAB: Southern Research Inst DIISOPROPYLCARBODIIMIDE DATE: 07/19/04 EXPERIMENT: 93020 TEST: 08 TIME: 09:14:52 TEST TYPE: CHRONIC CAGES FROM 0000 TO LAST CAGE PAGE: 1 CONT: N01-ES-05451 ROUTE: SKIN APPLICATION NTP C#: 93020D PATHOLOGIST: FARNELL, DANIEL CAS: 693-13-0 ------------------------------------------------------------------------------------------------------------------------------------ FINAL #1 MICE REASONS FOR REMOVAL: ALL REMOVAL DATE RANGE: ALL TREATMENT GROUPS: INCLUDE ALL NTP STATISTICAL ANALYSIS OF PRIMARY TUMORS REPORT: PEIRPT08 LAB: Southern Research Inst DIISOPROPYLCARBODIIMIDE DATE: 07/19/04 EXPERIMENT: 93020 TEST: 08 TIME: 09:14:52 TEST TYPE: CHRONIC CAGES FROM 0000 TO LAST CAGE CONT: N01-ES-05451 ROUTE: SKIN APPLICATION NTP C#: 93020D PATHOLOGIST: FARNELL, DANIEL CAS: 693-13-0 Mice(B6C3F1) ----------------------------- FOR ALL DOSES THE TUMOR RATES IN THE FOLLOWING TISSUES/ORGANS ARE BASED ON NUMBER OF TISSUES ...
https://ntp.niehs.nih.gov/data/tables/unorgpath/path11/08p08/index.html
Structural studies of organoboron compounds .64. Boron chelate formation with glycolohydroxamic acids, and the crystal and...Structural studies of organoboron compounds .64. Boron chelate formation with glycolohydroxamic acids, and the crystal and...
The syntheses of representative diphenyl- and difluoroboron chelates of 2-hydroxycarbohydroxamic acids (glycolohydroxamic acids) are reported. Crystals of 5-(1-hydroxycyclohexyl)-2,2-diphenyl-1,3-dioxa-4-azonia-2-borata-4-cyclo pentene, 2a, are triclinic. ...
http://www.chem.ubc.ca/structural-studies-organoboron-compounds-64-boron-chelate-formation-glycolohydroxamic-acids-and
Fabrication of a human recombinant collagen-based corneal substitute using carbodiimide chemistryFabrication of a human recombinant collagen-based corneal substitute using carbodiimide chemistry
Human recombinant collagen can be cross-linked with a variety of chemical cross-linking agents. Cross-linking methods can be tuned to confer collagen-based scaffolds with specific physical properties, improved antigenicity and thermal stability without impeding the ability of the material to integrate into the surrounding tissue and to promote regeneration. Here, we describe a method to cross-link human recombinant collagen using a water soluble carbodiimide. Carbodiimides are referred to as zero-length cross-linking agents as they are not incorporated into the final cross-link and thus pose minimal risk with respect to cytotoxicity. The resulting collagen-based scaffold possesses properties comparable to that of the human cornea and is thus suitable for use as a corneal substitute.. ...
http://liu.diva-portal.org/smash/record.jsf?pid=diva2:655378
Solid‐phase modification of chitosan hydrogel membranes and permeability properties of modified chitosan membranes<...
TY - JOUR. T1 - Solid‐phase modification of chitosan hydrogel membranes and permeability properties of modified chitosan membranes. AU - Kubota, Naoji. AU - Kikuchi, Yasuo. AU - Mizuhara, Yukako. AU - Ishihara, Tatsumi. AU - Takita, Yusaku. PY - 1993/12/5. Y1 - 1993/12/5. N2 - A novel preparation method for modified chitosan membranes was developed. Chitosan hydrogel membranes were prepared by immersing an aqueous acetic acid solution of chitosan in KOH solution and modified with 3,3′‐dithiodipropionic acid (DTPA), which has a functional group that causes the thiol ⟷ disulfide transition through a redox reaction. It was smoothly modified with DTPA even in a solid‐phase modification when carbodiimides were used as the condensing reagents. The chitosan membrane modified with DTPA was reduced with tri‐n‐butyl phosphine (MSH membrane) and then oxidized with iodine (MSS membrane). Permeabilities of KCl, sucrose, and urea through these modified chitosan membranes were investigated. The ...
https://kyushu-u.pure.elsevier.com/en/publications/solidphase-modification-of-chitosan-hydrogel-membranes-and-permea
1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride (EDC-HCl)1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride (EDC-HCl)
1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride (EDC-HCl or EDAC-HCl) is a zero-length crosslinker (CAS # 25952-53-8) used to conjugate carboxyl functional groups to primary amines as found in peptides and proteins.
https://www.proteochem.com/zerolengthcrosslinkersedchcledachcl-c-1_17_24.html
Carbodiimide inactivation of MMPs and effect on dentin bonding. - Semantic ScholarCarbodiimide inactivation of MMPs and effect on dentin bonding. - Semantic Scholar
The use of protein cross-linking agents during bonding procedures has been recently proposed to improve bond durability. This study aimed to use zymography and in situ zymography techniques to evaluate the ability of 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) cross-linker to inhibit matrix metalloproteinase (MMP) activity. The hypotheses tested were that: (1) bonding procedures increase dentin gelatinolytic activity and (2) EDC pre-treatment prevents this enzymatic activity. The zymographic assay was performed on protein extracts obtained from dentin powder treated with Optibond FL or Scotchbond 1XT with or without 0.3M EDC pre-treatment. For in situ zymography, adhesive/dentin interfaces were created with the same adhesives applied to acid-etched dentin slabs pre-treated or not with EDC conditioner. Zymograms revealed increased expression of dentin endogenous MMP-2 and -9 after adhesive application, while the use of EDC as a primer inactivated dentin gelatinases. Results of in situ zymograpy
https://www.semanticscholar.org/paper/Carbodiimide-inactivation-of-MMPs-and-effect-on-de-Mazzoni-Apolonio/3af7d0d8f2dd51848bae65de20555bf8170177fc
Cytochrome b5, cytochrome c, and cytochrome P-450 interactions with NADPH-cytochrome P-450 reductase in phospholipid vesicles.
Upon incubation of detergent-solubilized NADPH-cytochrome P-450 reductase and either cytochrome b5 or cytochrome c in the presence of a water-soluble carbodiimide, a 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide (EDC), covalently cross-linked compl
http://www.biomedsearch.com/nih/Cytochrome-b5-cytochrome-c-P/2847775.html
Biotage - Biotage® PS-Carbodiimide
Download the product note.. PS-Carbodiimide is a neutral, bound carbodiimide that can be used for the synthesis of amides and esters. The carbodiimide loading capacity is determined by 1H NMR (generation of Ac2O from AcOH in CDCl3). Amide formation may be conducted either without HOBt (Methods A), or with HOBt (Method B).. Excess HOBt can be scavenged after the reaction using MP-Carbonate Biotage® PS-Carbodiimide has been found to give superior results in comparison with N-Cyclohexylcarbodiimide-NI-Me PS resin and the quaternary carbodiimide resin P-EDC (Scheme 1, Table 1, click to enlarge table).. ...
http://www.pyrosequencing.com/product-page/biotage-ps-carbodiimide
EDAC (Water-Friendly Condensing Agents) | ScienceBlogsEDAC (Water-Friendly Condensing Agents) | ScienceBlogs
Awhile back, I discussed dicyclohexylcarbodiimide: a condensing agent that helps turn biological monomers (like amino acids) into polymers (like proteins). People use it a lot on peptide synthesizers for this purpose, where the peptides are made in organic solvents. A related compound, EDAC, works in water:
https://scienceblogs.com/moleculeoftheday/2009/03/02/edac-water-friendly-condensing
Biodegradable injectable sheet as transscleral drug delivery system | IOVS | ARVO JournalsBiodegradable injectable sheet as transscleral drug delivery system | IOVS | ARVO Journals
Purpose : To evaluate the in vitro and in vivo drug release of a biodegradable injectable sheet made of cross-linked chitosan and gelatin mixture. Methods : Gelatin and chitosan were solved in water and 1% acetic acid at concentrations of 5 wt% and 2.5 wt%, respectively. Then, 5 wt% gelatin and 2.5 wt% chitosan was mixed at the ratio of 3 : 2 (vol). The drug was mixed with the 3 wt% gelatin/1 wt% chitosan mixture. Fluorescein isothiocyanate (FITC), FITC-labeled dextran 150 kDa (FD150), and FITC-labeled albumin (FITC-ALB) were used as drugs. Immedeately after adding water soluble carbodiimide in the gelatin/chitosan/drug mixture at final concentration of 10 mg/mL, 3 μL of the mixture was cast in the polydimethylsilane (PDMS) mold (internal diameter; 2.76 mm, depth; 0.5 mm). Then, the cross-linked gels were dried for 1 hour at room temperutere to make flexible sheets. The sheets were incubated in phosphate buffered saline (PBS) at 37 degrees C. The drug concentration in PBS were measured ...
http://iovs.arvojournals.org/article.aspx?articleid=2641522
1-ethyl-1-methylmorpholinium bromide - Substance Information - ECHA1-ethyl-1-methylmorpholinium bromide - Substance Information - ECHA
About this substance This section provides an overview of the calculated volume at which the substance is manufactured or imported to the European Economic Area (EU28 + Iceland, Liechtenstein and Norway). Additionally, if available, information on the use of the substance and how consumers and workers are likely to be exposed to it can also be displayed here.. The use information is displayed per substance life cycle stage (consumer use, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites or in manufacturing). The information is aggregated from the data coming from REACH substance registrations provided by industry.. For a detailed overview on identified uses and environmental releases, please consult the registered substance factsheet.. Use descriptors are adapted from ECHA guidance to improve readability and may not correspond textually to descriptor codes described in Chapter R.12: Use Descriptor system of ECHA Guidance on information ...
https://echa.europa.eu/substance-information/-/substanceinfo/100.101.707
Structural biochemistry XIII: Synthesis of luteinizing hormone‐releasing hormone modification [Trp<sup>8</sup>]...
TY - JOUR. T1 - Structural biochemistry XIII. T2 - Synthesis of luteinizing hormone‐releasing hormone modification [Trp8]‐LH‐RH. AU - Pettit, George. AU - Smith, T. H.. PY - 1979/8. Y1 - 1979/8. N2 - A fragment condensation method was utilized for synthesis of the Trp8‐substituted luteinizing hormone‐releasing hormone (LH‐RH). Lert‐Butoxycarbonyl protection was employed for the α‐amino positions, and benzyl protection was used for the phenol group of Tyr and the imidazole nitrogen of His. Peptide bond‐forming reactions were performed using N‐hydroxysuccinimide (for Trp), dicyclohexylcarbodiimide‐1‐hydroxybenzotriazole, l‐ethyl‐3‐(3′‐dimethylaminopropyl)‐carbodiimide hydrochloride, or mixed carbonic anhydride methods. Biological evaluation of [Trp8]‐LH‐RH indicated no luteinizing hormone‐releasing activity or inhibition of luteinizing hormone release over the dose ranges studied.. AB - A fragment condensation method was utilized for synthesis of the ...
https://asu.pure.elsevier.com/en/publications/structural-biochemistry-xiii-synthesis-of-luteinizing-hormonerele
Plus itPlus it
Animals and antibodies. Fertilized Hisex chicken eggs (Gallus domesticus) were obtained from a local farm and incubated at 37°C and 65% humidity in a forced-draft incubator. Staging of the embryos was according to Hamburger and Hamilton (1951). Embryos of 3-11 d of incubation (E3-E11) were used.. To block the function of N-cadherin, the following antibodies were used: rat monoclonal antibody NCD-2 against chicken N-cadherin (a kind gift from M. Takeichi, Kyoto University, Kyoto, Japan) (Hatta and Takeichi, 1986) and NCD-2 Fab fragments. In preliminary experiments, a polyclonal rabbit antiserum against N-cadherin (Hatta et al., 1988) was also used (a kind gift from M. Takeichi). Rat IgG (ChromPure; Dianova, Hamburg, Germany) and NCD-2 Fc fragments served as a control.. For immunohistochemistry, the following antibodies against cadherins were used: rat monoclonal antibody NCD-2 and a rabbit polyclonal antiserum against chicken N-cadherin (affinity purified by protein A); mouse monoclonal antibody ...
http://www.jneurosci.org/content/18/14/5415
IUCr) (E)-1-Ferrocenyl-3-[2-(2-hy-dr-oxy-eth--oxy)phen-yl]prop-2-en-1-oneIUCr) (E)-1-Ferrocenyl-3-[2-(2-hy-dr-oxy-eth--oxy)phen-yl]prop-2-en-1-one
Ferrocenyl derivatives exhibit antitumor (Jaouen et al., 2004), antibacterial (Fouda et al., 2007), antifungal and antimalarial (Biot et al., 2004) activities. It was proved that the replacement of the aromatic group by the ferrocenyl moiety in penicillins and cephalosporins could improve their antibiotic activity (Edwards et al., 1975). Against this background, the title compound was chosen for X-ray structure analysis (Fig. 1).. In the title compound, the benzene ring makes dihedral angles of 10.84 (9) and 12.35 (9)°, respectively, with the substituted and unsubstituted cyclopentadienyl (Cp) rings of the ferrocenyl unit. In ferrocenyl unit, the two Cp rings are planar and are parallel to each other with a dihedral angle of 1.56 (9)° between them. The Fe atom lies in the middle of the two planes of Cp rings. The distances of the Fe1 atom from the centroids of the substituted and unsubstituted cyclopentadienyl rings are 1.646 (10) and 1.650 (12) Å, respectively. The Cg1-Fe1-Cg2 angle is ...
http://journals.iucr.org/e/issues/2013/03/00/is5242/index.html
Kinetics and mechanisms of reactions of [ferrocenyl(methoxy)carbene]pe by KL Budzinski and CF BernasconiKinetics and mechanisms of reactions of [ferrocenyl(methoxy)carbene]pe by KL Budzinski and CF Bernasconi
Kinetics and mechanisms of reactions of [ferrocenyl(methoxy)carbene]pentacarbonylchromium(0) with primary aliphatic amines in aqueous acetonitrile ...
https://aquila.usm.edu/fac_pubs/4401/
Dicyclohexylcarbodiimide - Registration Dossier - ECHADicyclohexylcarbodiimide - Registration Dossier - ECHA
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.. ...
https://echa.europa.eu/registration-dossier/-/registered-dossier/12761/7/3/3
TDMS Study 93020-06 Pathology TablesTDMS Study 93020-06 Pathology Tables
NTP Experiment-Test: 93020-06 INCIDENCE RATES OF NONNEOPLASTIC LESIONS BY ANATOMIC SITE (a) Report: PEIRPT03 Study Type: SUBCHRON 26-WEEK DIISOPROPYLCARBODIIMIDE (DIC) Date: 01/10/01 Route: SKIN APPLICATION Time: 11:03:02 Final#1/Mice Facility: BIORELIANCE Chemical CAS #: 693-13-0 Lock Date: 02/24/00 Cage Range: All Reasons For Removal: All Removal Date Range: All Treatment Groups: Include All a Number of animals examined microscopically at site and number of animals with lesion Page 1 NTP Experiment-Test: 93020-06 INCIDENCE RATES OF NONNEOPLASTIC LESIONS BY ANATOMIC SITE (a) Report: PEIRPT03 Study Type: SUBCHRON 26-WEEK DIISOPROPYLCARBODIIMIDE (DIC) Date: 01/10/01 Route: SKIN APPLICATION Time: 11:03:02 ____________________________________________________________________________________________________________________________________ MICE:P53+/-(C57BL/6) FEMALE VEHICLE 4.38 8.75 17.5 35 MG/KG 70 MG/KG CONTROL MG/KG MG/KG MG/KG ...
https://ntp.niehs.nih.gov/results/path/tablelistings/unorgpath/path11/06p03/index.html
Accela Chembio Inc (S)-4-ETHYL-4-HYDROXY-1H- 5G (S)-4-ETHYL-4-HYDROXY-1H- | Fisher ScientificAccela Chembio Inc (S)-4-ETHYL-4-HYDROXY-1H- 5G (S)-4-ETHYL-4-HYDROXY-1H- | Fisher Scientific
Shop a large selection of products and learn more about Accela Chembio Inc (S)-4-ETHYL-4-HYDROXY-1H- 5G (S)-4-ETHYL-4-HYDROXY-1H- .
https://www.fishersci.com/shop/products/s-4-ethyl-4-hydroxy-1h-5g/50251634
ethyl-3-amino-4-4-toluidino-benzoate | VWRethyl-3-amino-4-4-toluidino-benzoate | VWR
Learn more about ethyl-3-amino-4-4-toluidino-benzoate. We enable science by offering product choice, services, process excellence and our people make it happen.
https://us.vwr.com/store/product/21131904/ethyl-3-amino-4-4-toluidino-benzoate
6-ethyl-2-2-methylphenyl-quinoline-4-carboxylic-acid | VWR6-ethyl-2-2-methylphenyl-quinoline-4-carboxylic-acid | VWR
Learn more about 6-ethyl-2-2-methylphenyl-quinoline-4-carboxylic-acid. We enable science by offering product choice, services, process excellence and our people make it happen.
https://us.vwr.com/store/product/21165741/6-ethyl-2-2-methylphenyl-quinoline-4-carboxylic-acid
SPECTRUM 5-Ethyl-2,3-Dimethylpyrazine,25g - 49F668|E0828-25G - GraingerSPECTRUM 5-Ethyl-2,3-Dimethylpyrazine,25g - 49F668|E0828-25G - Grainger
Looking for SPECTRUM 5-Ethyl-2,3-Dimethylpyrazine,25g (49F668)? Graingers got your back. Price:$375.00. Easy ordering & convenient delivery. Log-in or register for your pricing.
https://www.grainger.com/product/SPECTRUM-TCI-15707-34-3-49F668
Metallocene-based antimalarials: An exploration into the influence of the ferrocenyl moiety on in vitro antimalarial activity...Metallocene-based antimalarials: An exploration into the influence of the ferrocenyl moiety on in vitro antimalarial activity...
To establish the role of the ferrocenyl moiety in the antiplasmodial activity of ferroquine, compounds in which this moiety is replaced by the corresponding ruthenium-based moieties were synthesized and evaluated. In both the sensitive (D 10) and resistant (K1) strains of Plasmodium falciparum, ruthenoquine analogues showed comparable potency to ferroquine. This suggests that a probable role of the ferrocenyl fragment is to serve simply as a hydrophobic spacer group. In addition, ferroquine analogues with different aromatic substituents were synthesized and evaluated. Unexpectedly high activity for quinoline compounds lacking the 7-chloro substituent suggests the ferrocenyl moiety may have an additive and/or synergistic effect. (c) 2007 Elsevier Ltd. All rights reserved.. ...
http://researchonline.lshtm.ac.uk/8413/
JFB | Free Full-Text | Optimization of Bicomponent Electrospun Fibers for Therapeutic Use: Post-Treatments to Improve Chemical...JFB | Free Full-Text | Optimization of Bicomponent Electrospun Fibers for Therapeutic Use: Post-Treatments to Improve Chemical...
Bicomponent electrospun nanofibers based on the combination of synthetic (i.e., aliphatic polyesters such as polycaprolactone (PCL)) and natural proteins (i.e., gelatin) have been extensively investigated as temporary platforms to instruct cells by the release of molecular/pharmaceutical signals for the regeneration of several tissues. Here, water soluble proteins (i.e., gelatin), strictly embedded to PCL, act as carriers of bioactive molecules, thus improving bioavailability and supporting cell activities during in vitro regeneration. However, these proteins are rapidly digested by enzymes, locally produced by many different cell types, both in vitro and in vivo, with significant drawbacks in the control of molecular release. Hence, we have investigated three post-processing strategies based on the use of different crosslinking agents-(1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride) (EDC), glyceraldehyde (GC), and 1,4-butanediol diglycidyl ether (BDDGE)-to delay the dissolution time of
http://www.mdpi.com/2079-4983/8/4/47
ZhejiangAnti - hydrolysis agent Zhejiang hydrolysis agent Zhejiang carbodiimide - Kunshan Dingfa Chemical Co., Ltd
Kunshan Dingfa Chemical Co., Ltd. was established in 2012, relying on domestic first-class scientific research institutes technical resources, professional commitment to PU flame retardants, engineering plastics additives and carbodiimide, hydrolysis agent, anti-hydrolysis agent. To the continued technological innovation, stable and reliable product quality and professional and efficient services to win the recognition of many Chinese and foreign customers. Tel: 13661970701.
http://www.dingfachemical.com/Zhejiang.html
PPT - The Use of Ferrocenyl Ligands in Asymmetric Catalytic Hydrogenation PowerPoint presentation | free to download - id:...PPT - The Use of Ferrocenyl Ligands in Asymmetric Catalytic Hydrogenation PowerPoint presentation | free to download - id:...
The Use of Ferrocenyl Ligands in Asymmetric Catalytic Hydrogenation – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 92595-MTE3N
http://www.powershow.com/view/92595-MTE3N/The_Use_of_Ferrocenyl_Ligands_in_Asymmetric_Catalytic_Hydrogenation_powerpoint_ppt_presentation
Patente US5304567 - Biocidal combinations containing 4,5-dichloro-2-cyclohexyl-3-isothiazolone ... - Google PatentesPatente US5304567 - Biocidal combinations containing 4,5-dichloro-2-cyclohexyl-3-isothiazolone ... - Google Patentes
Synergistic microbicidal compositions are disclosed, comprising 4,5-dichloro-2-cyclohexyl-3-isothiazolone and one or more known microbicides for more effective, and broader control of microorganisms in various systems.
http://www.google.es/patents/US5304567?dq=flatulence
Fluorescent Dye 425-N Acid - (U0097) - Products - Abnova
Fluorescent Dye derived from coumarine. Water insoluble and forms stable amide bond with primary amines via carbodiimide activation. (U0097) - Products - Abnova
http://www.abnova.com/products/products_detail.asp?catalog_id=U0097
Fluorescent Dye 555-N Acid - (U0129) - Products - Abnova
Fluorescent dye derived from dipyrrometheneboron difluoride. Water insoluble and forms stable amide bond with primary amines via carbodiimide activation. (U0129) - Products - Abnova
http://www.abnova.com/products/products_detail.asp?catalog_id=U0129
Cyclohexylstatine - Creative PeptidesCyclohexylstatine - Creative Peptides
3S,4S)-4-amino-5-cyclohexyl-3-hydroxypentanoicacid;ACHPA,(3S,4S)-4-Amino-5-cyclohexyl-3-hydroxy-pentanoicacid;105192-90-3;AC1NRAJQ;SCHEMBL7151431;ZINC2526313;AKOS015909015;AM001310;4-AMINO-5-CYCLOHEXYL-3-HYDROXY-PENTANOICACID;I14- ...
https://www.creative-peptides.com/product/cyclohexylstatine-item-cp26160-26103.html
Synthesis, structure, and biological activity of ferrocenyl carbohydrate conjugates | UBC ChemistrySynthesis, structure, and biological activity of ferrocenyl carbohydrate conjugates | UBC Chemistry
Seven ferrocenyl carbohydrate conjugates were synthesized. Coupling reactions of monosaccharide derivatives with ferrocene carbonyl chloride produced {6-N-(methyl 2,3,4-tri-O-acetyl-6-amino-6-deoxy-R-D-glucopyranoside)}1- ferrocene carboxamide (3), {1-O-(2,3,4,6-tetra-O-benzyl-D-glucopyranose)}-1-ferrocene carboxylate (4), and {6O- (1,2,3,4-tetra-O-acetyl-beta-D-glucopyranose)}-1-ferrocene carboxylate (5). Similarly, 1,1-bis(carbonyl chloride)ferrocene was coupled with the appropriate sugars to produce the disubstituted analogues bis {6-N-(methyl 2,3,4-tri- O-acetyl-6-amino-6-deoxy-R-D-glucopyranoside)}- 1,1-ferrocene carboxamide (8), bis {1-O-(2,3,4,6-tetra-O-benzyl-D- glucopyranose)}- 1,1-ferrocene carboxylate (9), and bis {6-O-(1,2,3,4-tetra-O-acetyl-beta-D-glucopyranose)}- 1,1-ferrocene carboxylate (10). {6-N-(Methyl-6-amino-6-deoxy-R-D-glucopyranoside)}-1-ferrocene carboxamide monohydrate (12) was synthesized via amide coupling of an activated ferrocenyl ester with the corresponding ...
https://www.chem.ubc.ca/synthesis-structure-and-biological-activity-ferrocenyl-carbohydrate-conjugates-0
Phenethanolamine Derivatives for Treatment of Respiratory Diseases - Patent applicationPhenethanolamine Derivatives for Treatment of Respiratory Diseases - Patent application
0028]Preferred compounds of the invention include: [0029]N-{3-[(2-{[6-({(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]- ethyl}-amino)hexyl]oxy}ethoxy)methyl]phenyl}-N-phenylurea; [0030]4-{(1R)-2-[(6-{2-[(2,6-dichlorobenzyl)oxy]ethoxy}hexyl)amino]-1-hyd- roxyethyl}-2-(hydroxymethyl)phenol; [0031]N-(1,1-biphenyl-4-yl)-N-{3-[(2-{[6-({(2R)-2-hydroxy-2-[4-hydroxy-- 3-(hydroxymethyl)phenyl]ethyl}amino) hexyl]oxy}ethoxy)methyl]phenyl}urea; [0032]N-cyclohexyl-N-{3-[(2-{[6-({(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxy- methyl)phenyl]ethyl}amino)hexyl]oxy}ethoxy)methyl]phenyl}urea; [0033]4-[(1R)-2-({6-[2-(benzyloxy)ethoxy]hexyl}amino)-1-hydroxyethyl]-2-(- hydroxymethyl)phenol; [0034]4-[(2-{[6-({(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]eth- yl}amino)-hexyl]oxy}ethoxy)methyl]benzenesulfonamide; [0035]4-{(1R)-1-hydroxy-2-[(6-{2-[(4-iodobenzyl)oxy]ethoxy}hexyl)amino]et- hyl}-2-(hydroxymethyl)phenol; [0036]3-[(2-{[6-({(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]eth- ...
http://www.patentsencyclopedia.com/app/20110009631
Plus itPlus it
Synthesis of L-SR15 and D-SR16. L-PGC (average molecular weight, 375 kDa) and D-PGC (average molecular weight, 344 kDa) were purchased from VisEn Medical, Inc. (Woburn, MA). L-PGC consists of poly-l-lysine (48 kDa) backbone grafted with monomethoxy-PEG (5 kDa, percent PEGylation, 30%). D-PGC consists of poly-d-lysine (44 kDa) grafted with PEG (percent PEGylation, 28%). The conjugation of Ce6 (Frontier Scientific, Logan, UT) to lysine residues in the PGC backbone was done using 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide HCl (EDC) as a coupling agent. In brief, total 1.7 mL mixture solutions, consisting of 1,140 μL of 9 μmol/L L-PGC or D-PGC in distilled water, 423 μL of 1.8 mmol/L Ce6 in 33 mmol/L Na2HPO4, and 120 μL of 13 mmol/L EDC in distilled water, were added into microcentrifuge tubes and gently shaken at 25°C in the dark for 20 hours. After reaction, the conjugates were purified by size exclusion chromatography (Bio-Gel P-10 gel, Bio-Rad, Hercules, CA) using 10 mmol/L phosphate ...
http://cancerres.aacrjournals.org/content/66/14/7225
Tin(ii) oxide carbodiimide and its relationship to SnO - Dalton Transactions (RSC Publishing)Tin(ii) oxide carbodiimide and its relationship to SnO - Dalton Transactions (RSC Publishing)
The compound Sn2O(CN2) was obtained as a brick-red crystalline powder from a solid-state reaction of equimolar amounts of SnCl2, SnO and Li2(CN2). Thermal analysis of the reaction indicates the formation of two intermediate compounds until Sn2O(CN2) is formed at 400 °C. The crystal structure of Sn2O(CN2) was
https://pubs.rsc.org/en/content/articlelanding/2018/DT/c8dt02747a
Synthesis of C-aryl-N-(2-hydroxyphenylmethyl)-nitrones and their reaction with diphenylborinic or carboxylic acid derivatives....Synthesis of C-aryl-N-(2-hydroxyphenylmethyl)-nitrones and their reaction with diphenylborinic or carboxylic acid derivatives....
The syntheses of a number of aromatic aldonitrones of N-(2-hydroxyphenylmethyl)hydroxylamine and their subsequent reactions with diphenylborinic or carboxylic acid derivatives are reported. Crystals of 8-(4-dimethylaminophenylmethylene)-6,6-diphenyl-5,7-dioxa-8-azonia-6-bor ata-5H-6,7,8,9-tetrahydrobenzocycloheptene, 2b, are triclinic. ...
https://chem.ubc.ca/synthesis-c-aryl-n-2-hydroxyphenylmethyl-nitrones-and-their-reaction-diphenylborinic-or-carboxylic
2-cyclohexyl-4-methyl-5-phenylmethoxypent-1-en-3-ol | C19H28O2 - ChemSynthesis
2-cyclohexyl-4-methyl-5-phenylmethoxypent-1-en-3-ol - chemical structural formula, chemical names, chemical properties, synthesis references
http://www.chemsynthesis.com/base/chemical-structure-19865.html
CAS 115883-22-2 | 2,6-Piperidinedione, 3-(4-aminophenyl)-3-cyclohexyl- | CAS Number 115883-22-2 | angenechem.com
2,6-Piperidinedione, 3-(4-aminophenyl)-3-cyclohexyl-. CAS 115883-22-2. Molecular Formula:C17H22N2O2. Molecular Weight:C17H22N2O2.
https://www.angenechem.com/115883-22-2
NIOSHTIC-2 Publications Search - 00081333 - Hydroquinone, NIOSH-Analytical Method No. S57.NIOSHTIC-2 Publications Search - 00081333 - Hydroquinone, NIOSH-Analytical Method No. S57.
Analytical methodology (No. S57) for determining levels of hydroxyquinone (123319) in aerosols collected on cellulose ester filters is described. An outline of principles of the methodology, demonstrated sensitivity and range of concentrations detectable, interference from other compounds, precision and accuracy of the method, advantages and disadvantages of the method and apparatus and reagents n
https://www.cdc.gov/niosh/nioshtic-2/00081333.html
Publications | Max Planck Institute of Colloids and Interfaces
Allouch, F.; Vologdin, N. V.; Cattey, H.; Pirio, N.; Naoufal, D.; Kanj, A.; Smaliy, R. V.; Savateev, A.; Marchenko, A.; Hurieva, A. et al.; Koidan, H.; Kostyuk, A. N.; Hierso, J.-C.: Ferrocenyl (P,N)-diphosphines incorporating pyrrolyl, imidazolyl or benzazaphospholyl moieties: Synthesis, coordination to group 10 metals and performances in palladium-catalyzed arylation reactions. Journal of Organometallic Chemistry 735, pp. 38 - 46 (2013 ...
https://www.mpikg.mpg.de/publication-search/5755807?page=3&person=%2Fpersons%2Fresource%2Fpersons188005
PQR | 5-ethyl-5-phenyl-1-(phenylsulfonyl)-2,4-imidazolidinedionePQR | 5-ethyl-5-phenyl-1-(phenylsulfonyl)-2,4-imidazolidinedione
You are viewing an interactive 3D depiction of the molecule 5-ethyl-5-phenyl-1-(phenylsulfonyl)-2,4-imidazolidinedione (C17H16N2O4S) from the PQR.
http://pqr.pitt.edu/mol/HWWVPVUGOLNSEB-QGZVFWFLSA-N
3R,5R,6S,7S,9R,11E,13R,14R)-14-Ethyl-6-hydroxy-3,5,7,9,13-pentamethyloxacyclotetradec-11-ene-2,4,10-trione | C20H32O5 |...3R,5R,6S,7S,9R,11E,13R,14R)-14-Ethyl-6-hydroxy-3,5,7,9,13-pentamethyloxacyclotetradec-11-ene-2,4,10-trione | C20H32O5 |...
Structure, properties, spectra, suppliers and links for: (3R,5R,6S,7S,9R,11E,13R,14R)-14-Ethyl-6-hydroxy-3,5,7,9,13-pentamethyloxacyclotetradec-11-ene-2,.
http://www.chemspider.com/Chemical-Structure.4445265.html
What to Have in Your EveryDay Carry (EDC) KitWhat to Have in Your EveryDay Carry (EDC) Kit
1ShareIf you are new to prepping, or interested but not sure that its for you, a great place to start out is with what to have in your Every Day Carry (EDC)...
https://modernsurvivalonline.com/what-to-have-in-your-everyday-carry-edc-kit/?replytocom=115993
Interactions between the photosystem II subunit PsbS and xanthophylls studied in vivo and in vitro | IRIS Università degli...
The photosystem II subunit PsbS is essential for excess energy dissipation (qE); however, both lutein and zeaxanthin are needed for its full activation. Based on previous work, two models can be proposed in which PsbS is either 1) the gene product where the quenching activity is located or 2) a proton-sensing trigger that activates the quencher molecules. The first hypothesis requires xanthophyll binding to two PsbS-binding sites, each activated by the protonation of a dicyclohexylcarbodiimide-binding lumen-exposed glutamic acid residue. To assess the existence and properties of these xanthophyll-binding sites, PsbS point mutants on each of the two Glu residues PsbS E122Q and PsbS E226Q were crossed with the npq1/npq4 and lut2/ npq4 mutants lacking zeaxanthin and lutein, respectively. Double mutants E122Q/npq1 and E226Q/npq1 had no qE, whereas E122Q/lut2 and E226Q/lut2 showed a strong qE reduction with respect to both lut2 and single glutamate mutants. These findings exclude a specific ...
https://flore.unifi.it/handle/2158/256286
HOGENOM: BASUB1 1 PE3152
ID BASUB1_1_PE3152 STANDARD; PRT; 192 AA. AC BASUB1_1_PE3152; O32074; DT 00-JAN-0000 (Rel. 1, Created) DT 00-JAN-0000 (Rel. 2, Last sequence update) DT 00-JAN-0000 (Rel. 3, Last annotation update) DE RecName: Full=Thiamine transporter ThiT;AltName: Full=Thiamine ECF DE transporter S component ThiT; (BASUB1_1.PE3152). GN Name=thiT; Synonyms=yuaJ; OrderedLocusNames=BSU30990; OS BACILLUS SUBTILIS SUBSP. SUBTILIS STR. 168. OC Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus. OX NCBI_TaxID=224308; RN [0] RP -.; RG -.; RL -.; CC -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS BASUB1_1.PE3152. CC Bacillus subtilis subsp. subtilis str. 168 chromosome, complete genome. CC sequence. CC -!- ANNOTATIONS ORIGIN:THIT_BACSU CC -!- FUNCTION: Probably a thiamine-binding protein that interacts with CC the energy-coupling factor (ECF) ABC-transporter complex. Unlike CC classic ABC transporters this ECF transporter provides the energy CC necessary to transport a number of different substrates. The CC ...
http://pbil.univ-lyon1.fr/cgi-bin/acnuc-search-id?query=BASUB1_1_PE3152&db=HOGENOM&ident=ACNUC17686
ASSAYS AND ASSAY DEVICES - Patent applicationASSAYS AND ASSAY DEVICES - Patent application
0281] Materials Preparation--To activate the labeling beads, one ml of 0.2 μm Time Resolved Fluorescence latex microparticles (MPs) (Thermo Fisher Fremont, Calif.) at 10% (w/v) solids are combined with 1 ml of 0.5 M MES buffer (pH 6.0), 5.5 ml of deionized H20, 2.3 ml of 50 mg of N-hydroxysuccinimide (ISIHS; Product #24500; Pierce Chemical Company, Rockford, Ill.) per ml deionized H2O and 0.2 ml of 5 mg of 1-ethyl-3-(3-dimethylamino-propyl) carbodiimide hydrochloride (EDC; Product #22980; Pierce Chemical Company) in deionized H2O. The resultant mixture is sonicated on ice for 40 seconds and then allowed to react on a shaker at RT for 30 minutes. The activated MPs are then centrifuged at 100 C at 10,000×g and washed three times with cold 50 mM MES buffer (pH 6.0) by resuspension and centrifugation cycles. In a typical procedure, the final pellet of MPs is suspended in 3.7 ml of 50 mM MES buffer (pH 6.0) and 2.3 ml of 1.0 mg of mouse anti-(Anti-NTproBNP peptide 63-71 antibody (Hytest., Turku, ...
http://www.patentsencyclopedia.com/app/20120149128
Synthesis and mass-spectrometric characterization of human serum albumins modified by covalent binding of two non-steroidal...Synthesis and mass-spectrometric characterization of human serum albumins modified by covalent binding of two non-steroidal...
Human serum albumins modified by covalently bound tolmetin or zomepirac were synthesized as models for similar products formed in vivo from acyl glucuronides. Activated esters of both drugs were prepared with 1-ethyl-3-(3-dimethylaminopropyl)-carbodi-imide, and then allowed to react with human serum albumin. Tryptic digests of both protein products were analysed by HPLC to identify peptides containing covalently bound drugs, and binding sites on albumin were identified by high-performance tandem MS. Three binding sites were common to both products, i.e. lysine-195, -199 and -351. Three further modified residues were identified for the tolmetin-albumin product, i.e. aspartic acid 1, and lysine-524 and -536. ...
http://www.biochemj.org/content/311/2/431
R)-(-)-Alpha-[(S)-2-(diphenylphosphino)ferrocenyl]benzylamine - Alfa ChemistryR)-(-)-Alpha-[(S)-2-(diphenylphosphino)ferrocenyl]benzylamine - Alfa Chemistry
(R)-(-)-Alpha-[(S)-2-(diphenylphosphino)ferrocenyl]benzylamine/ACM498580486 can be provided in Alfa Chemistry. We are dedicated to provide our customers the best products and services.
http://www.alfa-chemistry.com/cas_498580-48-6.htm
1-Cyclohexyl-1-butanol 4352-42-5 MSDS, Safety Technical Specifications MSDS1-Cyclohexyl-1-butanol 4352-42-5 MSDS, Safety Technical Specifications MSDS
1-Cyclohexyl-1-butanol 4352-42-5 MSDS report, 1-Cyclohexyl-1-butanol MSDS safety technical specifications search, 1-Cyclohexyl-1-butanol safety information specifications ect.
http://www.molbase.com/en/msds_4352-42-5-moldata-70873.html
Biotage - Biotage® PS-HOBt(HL)Biotage - Biotage® PS-HOBt(HL)
Download the product note.. Biotage®PS-HOBt(HL) is a sulfonamide-linked, polymer supported equivalent of 1-hydroxybenzotriazole (HOBt). PS-HOBt(HL) is used to generate bound HOBt active esters, which can either be made and used in situ, or isolated and stored as stable intermediates. Treatment of bound HOBt esters with an amine leads to amide formation in generally high purity without the need for further purification.. To date, the recommended procedure for loading PS-HOBt has required PyBroP as the coupling agent. We have developed an improved loading procedure based on the use of diisopropylcarbodiimide and DMAP. The new procedure has proven to be much more reliable, efficient, and cost effective. It requires fewer equivalents of carboxylic acid and does not require a double coupling as is the case when PyBroP is used.. Polymer-supported active esters offer some unique advantages for parallel amide synthesis. The polymer-supported active esters of PS-HOBt(HL) can be prepared using the ...
https://www.biotage.com/product-page/biotage-ps-hobthl
Patent US7918899 - Variably crosslinked tissue - Google PatentsPatent US7918899 - Variably crosslinked tissue - Google Patents
Non-glutaraldehyde fixation of an organ or a prosthesis for implantation in a mammal is based upon carbodiimide treatment. A solution containing a sterilizing agent, such as EDC, in combination with a coupling enhancer, such as Sulfo-NHS, and a high concentration of a diamine cross linking agent is used. As a result, only minimal surface reduction occurs during fixation, and the resultant products show a dramatic increase in resistance to calcification.
http://www.google.com.au/patents/US7918899
Carboxyl Group: Definition And Function | Science TrendsCarboxyl Group: Definition And Function | Science Trends
Carboxyl is an organic functional group that is made out of a single carbon atom double bonded to an oxygen atom, and single bonded to a hydroxyl group. The
https://sciencetrends.com/carboxyl-group-definition-and-function/
3-ethyl-1-phenyl-4,9-dihydro-3H-beta-carboline | C19H18N2 - ChemSynthesis
3-ethyl-1-phenyl-4,9-dihydro-3H-beta-carboline - chemical structural formula, chemical names, chemical properties, synthesis references
http://www.chemsynthesis.com/base/chemical-structure-9030.html
N,N-DicyclohexylcarbodiimideN,N'-Dicyclohexylcarbodiimide
The C−N=C=N−C core of carbodiimides (N=C=N) is linear, being related to the structure of allene. The molecule has idealized C2 ... Carbodiimide Jeffrey S. Albert, Andrew D. Hamilton, Amy C. Hart, Xiaoming Feng, Lili Lin, Zhen Wang (2017). "1,3‐ ... Carbodiimides" (PDF). Journal of Organic Chemistry. 43 (25): 4689-4690. doi:10.1021/jo00419a001. Campbell, T. W.; Monagle, J. J ... Jászay, Z. M.; Petneházy, I.; Töke, L.; Szajáni, B. (1987). "Preparation of Carbodiimides Using Phase-Transfer Catalysis". ...
https://en.wikipedia.org/wiki/N,N'-Dicyclohexylcarbodiimide
DeLos F. DeTarDeLos F. DeTar
DeTar, D.F.; Silverstein, R. (1966). "Reactions of Carbodiimides. I. The Mechanisms of the Reactions of Acetic Acid with ...
https://en.wikipedia.org/wiki/DeLos_F._DeTar
AmidineAmidine
Ulrich, Henri (2007). Chemistry and technology of carbodiimides. Chichester, England: John Wiley & Sons. ISBN 9780470065105. ( ... and can be accessed by reaction of a carbodiimide with an organometallic compound such as methyl lithium. They are used widely ...
https://en.wikipedia.org/wiki/Amidine
HydrazineHydrazine
Weinshenker NM, Shen CM, Wong JY (1977). "Polymeric Carbodiimide. Preparation". Org. Synth. 56: 95. doi:10.15227/orgsyn. ...
https://en.wikipedia.org/wiki/Hydrazine
HydroaminationHydroamination
Koller, J.; Bergman, R.G. (2010). "Highly Efficient Aluminum-Catalyzed Hydro-amination/-hydrazination of Carbodiimides". ...
https://en.wikipedia.org/wiki/Hydroamination
HaptenHapten
Carbodiimide: A group of compounds with a general formula of R-N=C=N-R′, where R and R′ are either aliphatic (i.e., ... Agents with at least two chemically reactive groups such as carbodiimide or glutaraldehyde are to aid the conjugation of ... Bauminger, Sara; Wilchek, Meir (1980). "[7] the use of carbodiimides in the preparation of immunizing conjugates". ... diethylcarbodiimide) or aromatic (i.e., diphenylcarbodiimide). Conjugation using a carbodiimide requires the presence of α or ɛ ...
https://en.wikipedia.org/wiki/Hapten
Carbon disulfideCarbon disulfide
Li, Zhen; Mayer, Robert J.; Ofial, Armin R.; Mayr, Herbert (2020-04-27). "From Carbodiimides to Carbon Dioxide: Quantification ...
https://en.wikipedia.org/wiki/Carbon_disulfide
IsocyanateIsocyanate
Carbodiimides are produced by the decarboxylation of alkyl and aryl isocyanate using phosphine oxides as a catalyst: C 6 H 11 ... In terms of bonding, isocyanates are closely related to carbon dioxide (CO2) and carbodiimides (C(NR)2). The C−N=C=O unit that ... Li, Zhen; Mayer, Robert J.; Ofial, Armin R.; Mayr, Herbert (2020-04-27). "From Carbodiimides to Carbon Dioxide: Quantification ...
https://en.wikipedia.org/wiki/Isocyanate
Carbon dioxideCarbon dioxide
ISBN 978-0-07-032760-3. Li Z, Mayer RJ, Ofial AR, Mayr H (May 2020). "From Carbodiimides to Carbon Dioxide: Quantification of ...
https://en.wikipedia.org/wiki/Carbon_dioxide
N,N-DiisopropylcarbodiimideN,N'-Diisopropylcarbodiimide
N,N′-Diisopropylcarbodiimide is a carbodiimide used in peptide synthesis. As a liquid, it is easier to handle than the commonly ... "Reinvestigation of the reactions of carbodiimides with alkoxycarbonylamino acid symmetrical anhydrides : Isolation of two N'- ... Carbodiimides, Reagents for biochemistry, Biochemistry, Biochemistry methods, Isopropyl compounds). ...
https://en.wikipedia.org/wiki/N,N'-Diisopropylcarbodiimide
MaserMaser
... and carbodiimide (HNCNH). Water molecules in star-forming regions can undergo a population inversion and emit radiation at ... "Interstellar Carbodiimide (HNCNH): A New Astronomical Detection from the GBT Primos Survey Via Maser Emission Features". The ...
https://en.wikipedia.org/wiki/Maser
Nucleic acid structure determinationNucleic acid structure determination
... carbodiimide, also known as EDC, is a water-soluble carbodiimide that exhibits similar reactivity as CMC, and is also used for ... The carbodiimide moiety can also form covalent adducts at exposed nucleobases, which are uracil, and to a smaller extent ... 1-cyclohexyl-(2-morpholinoethyl)carbodiimide metho-p-toluene sulfonate, also known as CMCT or CMC, is the most commonly used ... Wang, PY; Sexton, AN; Culligan, WJ; Simon, MD (2019). "Carbodiimide reagents for the chemical probing of RNA structure in cells ...
https://en.wikipedia.org/wiki/Nucleic_acid_structure_determination
ImideImide
Organic compounds called carbodiimides have the formula RN=C=NR. They are unrelated to imides. The PubChem links gives access ...
https://en.wikipedia.org/wiki/Imide
Peptide synthesisPeptide synthesis
Conversely, the related carbodiimide 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) is often used for solution-phase ... Carbodiimide activation opens the possibility for racemization of the activated amino acid. Racemization can be circumvented ... Carbodiimides such as dicyclohexylcarbodiimide (DCC) and diisopropylcarbodiimide (DIC) are frequently used for amide bond ... Some coupling reagents omit the carbodiimide completely and incorporate the HOAt/HOBt moiety as an aminium/uronium or ...
https://en.wikipedia.org/wiki/Peptide_synthesis
Hexa(tert-butoxy)ditungsten(III)Hexa(tert-butoxy)ditungsten(III)
... carbodiimide and allene adducts of hexakis (Trifluoromethyl t-botoxy) ditungsten. A comparison of ligand binding to W2(Ot-Bu)6 ...
https://en.wikipedia.org/wiki/Hexa(tert-butoxy)ditungsten(III)
UreaUrea
... s are closely related to biurets and related in structure to amides, carbamates, carbodiimides, and thiocarbamides. Urea ...
https://en.wikipedia.org/wiki/Urea
Fluorescence in the life sciencesFluorescence in the life sciences
... via activation with carbodiimide and subsequent coupling with amine); thiol (e.g. via maleimide or iodoacetamides); azide (e.g ...
https://en.wikipedia.org/wiki/Fluorescence_in_the_life_sciences
DiazomethaneDiazomethane
... whose minor tautomer is carbodiimide, is an isomer of diazomethane. Less stable but still isolable isomers of diazomethane ...
https://en.wikipedia.org/wiki/Diazomethane
Contrast-enhanced ultrasoundContrast-enhanced ultrasound
These ligands are attached to the microbubbles using carbodiimide, maleimide, or biotin-streptavidin coupling. Biotin- ...
https://en.wikipedia.org/wiki/Contrast-enhanced_ultrasound
Weinreb ketone synthesisWeinreb ketone synthesis
Various carbodiimide-, hydroxybenzotriazole-, and triphenylphosphine-based couplings have been reported specifically for this ...
https://en.wikipedia.org/wiki/Weinreb_ketone_synthesis
Rhodium(II) acetateRhodium(II) acetate
Hubert, A. J.; Feron, A.; Warin, R.; Teyssie, P. (1976). "Synthesis of iminoaziridines from carbodiimides and diazoesters : A ...
https://en.wikipedia.org/wiki/Rhodium(II)_acetate
Richard DronskowskiRichard Dronskowski
His research focuses on the following topics: solid-state chemistry quantum chemistry nitrides carbodiimides guanidinates ... Metal Carbodiimides as Molecular Negative Electrode Materials for Lithium‐ and Sodium‐Ion Batteries with Excellent Cycling ... the First Carbodiimide of a Magnetic Transition Metal". Inorganic Chemistry. American Chemical Society (ACS). 44 (9): 3001-3003 ...
https://en.wikipedia.org/wiki/Richard_Dronskowski
Pauson-Khand reactionPauson-Khand reaction
The total synthesis of physostigmine by the Mukai group utilized the PKR on a carbodiimide. Cyclobutadiene also lends itself to ...
https://en.wikipedia.org/wiki/Pauson–Khand_reaction
CarbonesCarbones
Carbodiimides, and Their Selenium, Tellurium, and Phosphorus Analogues". Science of Synthesis. 18: 65-320. doi:10.1055/sos-SD- ...
https://en.wikipedia.org/wiki/Carbones
BioconjugationBioconjugation
Azie, O; Greenberg, ZF; Batich, CD; Dobson, JP (2019). "Carbodiimide Conjugation of Latent Transforming Growth Factor β1 to ...
https://en.wikipedia.org/wiki/Bioconjugation
Astrophysical maserAstrophysical maser
2012), "Interstellar Carbodiimide (HNCNH) - A New Astronomical Detection from the GBT PRIMOS Survey via Maser Emission Features ... "Interstellar Carbodiimide (HNCNH): A New Astronomical Detection from the GBT PRIMOS Survey via Maser Emission Features". The ...
https://en.wikipedia.org/wiki/Astrophysical_maser
Superparamagnetic relaxometrySuperparamagnetic relaxometry
The Ab is conjugated to the superparamagnetic iron oxide NP by different methods including the carbodiimide method. The ...
https://en.wikipedia.org/wiki/Superparamagnetic_relaxometry
ProteinoidProteinoid
... amidinium carbodiimide, is formed in primitive Earth experiments and is effective in dilute aqueous solutions. When present in ...
https://en.wikipedia.org/wiki/Proteinoid
Pfitzner-Moffatt oxidationPfitzner-Moffatt oxidation
J. G. Moffatt, "Sulfoxide-Carbodiimide and Related Oxidations" in Oxidation vol. 2, R. L. Augustine, D. J. Trecker, Eds. ( ... Parikh-Doering oxidation - mechanistically similar alcohol oxidation, replaces carbodiimide with sulfur trioxide Corey-Kim ... formed by a reaction between DSMO and the carbodiimide. This species is highly reactive and is attacked by the alcohol. ...
https://en.wikipedia.org/wiki/Pfitzner–Moffatt_oxidation
Oxidative phosphorylationOxidative phosphorylation
... the oligomycin sensitivity conferring protein is essential for dicyclohexyl carbodiimide-sensitive ATPase". Biochim. Biophys. ...
https://en.wikipedia.org/wiki/Oxidative_phosphorylation
Carbodiimide - WikipediaCarbodiimide - Wikipedia
As weak bases, carbodiimides bind to Lewis acids to give adducts. Carbodiimides are reagents for the Moffatt oxidation, a ... 1-cyclohexyl-(2-morpholinoethyl)carbodiimide metho-p-toluene sulfonate is a carbodiimide developed for the chemical probing of ... though this mostly occurs with low melting point carbodiimides that are liquids at room temperature. Solid diaryl carbodiimides ... Three principal resonance structures describe carbodiimides: RN=C=NR ↔ RN+≡C-N−R ↔ RN−-C≡N+R The N=C=N core is relatively ...
https://en.wikipedia.org/wiki/Carbodiimide
CDC - NIOSH Pocket Guide to Chemical Hazards - Index of Chemical Names : CCDC - NIOSH Pocket Guide to Chemical Hazards - Index of Chemical Names : C
Carbodiimide. 420-04-2. GS5950000. Carbofuran *. 1563-66-2. FB9450000. Carbolic acid. 108-95-2. SJ3325000. ...
https://www.cdc.gov/niosh/npg/npgsyn-c.html
About: dicyclohexyl-carbodiimide
... Goto Sponge NotDistinct Permalink An Entity of Type : http://purl.org/allie/ontology/201108# ...
http://data.allie.dbcls.jp/describe/?url=http://purl.org/allie/id/longform/2187458&urilookup=1
Data archive for Carbodiimide-induced formation of transient polyether cagesData archive for "Carbodiimide-induced formation of transient polyether cages"
... on treatment with carbodiimides, give transient macrobicyclic cages analogous to polyether cages. Negative templation effects ...
https://sc.lib.miamioh.edu/handle/2374.MIA/6850
86332-16-3 N-Cyclohexyl-N-(4-(dimethylamino)naphthyl)carbodiimide86332-16-3 N-Cyclohexyl-N'-(4-(dimethylamino)naphthyl)carbodiimide
... carbodiimide from Synchem; 100 mg for a price of 300 €; allways in stock! ...
https://www.synchem.de/product/ncd-4/
DIMETHYLAMINOPROPYL)-3-ETHYL CARBODIIMIDE HCL, 1-(3- - RalinbvDIMETHYLAMINOPROPYL)-3-ETHYL CARBODIIMIDE HCL, 1-(3- - Ralinbv
Home / Pharmaceuticals / COUPLING AGENTS-P / DIMETHYLAMINOPROPYL)-3-ETHYL CARBODIIMIDE HCL, 1-(3-. ...
https://ralinbv.com/product/dimethylaminopropyl-3-ethyl-carbodiimide-hcl-1-3/
Registration Dossier - ECHARegistration Dossier - ECHA
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.. ...
https://www.echa.europa.eu/web/guest/registration-dossier/-/registered-dossier/13695/7/3/5
Dicyclohexylcarbodiimide M930062Dicyclohexylcarbodiimide M930062
Bis(cyclohexyl)carbodiimide. *DCC. Short-Term Toxicity. *2 weeks (Topical Application) (C93021) Completed * Rats: F344/N; Mice ...
https://ntp.niehs.nih.gov/whatwestudy/testpgm/status/ts-m930062.html
Use of Bead-Based Serologic Assay to Evaluate Chikungunya Virus Epidemic, Haiti - Volume 24, Number 6-June 2018 - Emerging...
... carbodiimide method (Calbiochem, Woburn, MA, USA). The recombinant CHIKV wild-type and mutant (A226V) envelope 1 (E1) antigens ...
https://wwwnc.cdc.gov/eid/article/24/6/17-1447
New molecular motor runs on chemical fuel | Science Linx News | Science LinX | University of GroningenNew molecular motor runs on chemical fuel | Science Linx News | Science LinX | University of Groningen
Energy for the rotation is provided by a carbodiimide. Motor-3 can harvest the energy by converting this carbodiimide to urea. ...
https://www.rug.nl/sciencelinx/nieuws/2022/07/new-molecular-motor-runs-on-chemical-fuel
C&L InventoryC&L Inventory
Bis(2,6-diisopropylphenyl)carbodiimide. 2162-74-5. Notified classification and labelling according to CLP criteria ...
https://echa.europa.eu/information-on-chemicals/cl-inventory-database/-/discli/details/10642
Articles | Polymer Chemistry and Biomaterials (PCB-PBM)Articles | Polymer Chemistry and Biomaterials (PCB-PBM)
Everaerts, F., Torriani, M., Hendriks, M. & Feijen, J. (2007). Quantification of carboxyl groups in carbodiimide cross-linked ...
https://www.utwente.nl/en/tnw/pbm/articles/
Cas 1405-86-3,Glycyrrhizic acid | lookchemCas 1405-86-3,Glycyrrhizic acid | lookchem
Stage #1: glycyrrhizin With 1-hydroxy-pyrrolidine-2,5-dione; dicyclohexyl-carbodiimide In 1,4-dioxane at 0 - 5℃;. Stage #2: L- ... Stage #1: glycyrrhizin With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl- ... With benzotriazol-1-ol; dicyclohexyl-carbodiimide In pyridine; DMF (N,N-dimethyl-formamide). 60%. ...
https://www.lookchem.com/casno1405-86-3.html
Periodic Table of Elements: Common Compounds of Hydrogen - H (EnvironmentalChemistry.com)Periodic Table of Elements: Common Compounds of Hydrogen - H (EnvironmentalChemistry.com)
N,N-Dicyclohexyl Carbodiimide. Formula: C13H22N2. *N,N-Diisopropylethyl Amine. Formula: C8H19N. *N,N-Dimethylaniline. Formula: ...
https://environmentalchemistry.com/yogi/periodic/Sn-compounds.html
NIOSHTIC-2 Search Results - Full View
The aspartate was subsequently labeled with the N-cyclohexyl-N-(4-(dimethylamino)naphthyl)carbodiimide (NCD-4) fluorophore, ...
http://www2a.cdc.gov/nioshtic-2/BuildQyr.asp?s1=respiratory&f1=%2A&Startyear=&Adv=0&terms=1&EndYear=&Limit=10000&sort=&D1=10&PageNo=499&RecNo=4982&View=f&
Hydroamination of Alkenes and Alkynes with Group 2 Centred Catalysts - Research output - the University of Bath's research...
Carbodiimide insertion reactions of homoleptic heavier alkaline earth amides and phosphides. Barrett, A. G. M., Crimmin, M. R. ... Heavier group 2 element catalyzed hydrophosphination of carbodiimides. Crimmin, M. R., Barrett, A. G. M., Hill, M. S., ...
https://researchportal.bath.ac.uk/en/projects/hydroamination-of-alkenes-and-alkynes-with-group-2-centred-cataly/publications/
The Effect of surface modification on gliding ability of decellularized flexor tendon in a canine model in vitro - Fingerprint ...
Dive into the research topics of The Effect of surface modification on gliding ability of decellularized flexor tendon in a canine model in vitro. Together they form a unique fingerprint. ...
https://mayoclinic.pure.elsevier.com/en/publications/the-effect-of-surface-modification-on-gliding-ability-of-decellul/fingerprints/
CDC - NIOSH Pocket Guide to Chemical Hazards - CyanamideCDC - NIOSH Pocket Guide to Chemical Hazards - Cyanamide
Carbodiimide, Cyanogen nitride, Hydrogen cyanamide [Note: Cyanamide is also a synonym for Calcium cyanamide.] Crystalline solid ... Amidocyanogen, Carbimide, Carbodiimide, Cyanogen nitride, Hydrogen cyanamide [Note: Cyanamide is also a synonym for Calcium ...
https://www.cdc.gov/niosh/npg/npgd0160.html
Phosphorus Based Catalyst Market Forecast, Trend Analysis & Competition Tracking - Global Review 2018 to 2028Phosphorus Based Catalyst Market Forecast, Trend Analysis & Competition Tracking - Global Review 2018 to 2028
Phosphorus-based catalysts are used for the production of carbodiimides from isocyanates. ...
https://www.factmr.com/report/1556/phosphorus-based-catalyst-market
Early detection of cerebrovascular pathology and protective antiviral immunity by MRI | eLifeEarly detection of cerebrovascular pathology and protective antiviral immunity by MRI | eLife
1-Ethyl-3-[3-dimethylaminopropyl]carbodiimide hydrochloride. Sigma Aldrich. Cat# E6383. Chemical compound, drug. sulfo-N- ... carbodiimide hydrochloride (EDAC) and sulfo-N-hydroxysuccinimide (Sulfo-NHS) were added to the particle suspension. The final ...
https://elifesciences.org/articles/74462
Structural basis for microtubule recognition by the human kinetochore Ska complex | Nature CommunicationsStructural basis for microtubule recognition by the human kinetochore Ska complex | Nature Communications
For this purpose, we crosslinked the Ska1-MTBD/Ska complex with MTs, using 1-ethyl-3-[3-dimethylaminopropyl] carbodiimide ...
https://www.nature.com/articles/ncomms3964?error=cookies_not_supported&code=c27bfc82-fbde-43c3-a7bd-c12edf0b14ff
US20080140094A1 - Unitary surgical device and method - Google Patents
150000001718 carbodiimides Chemical class 0.000 description 3 * 230000003848 cartilage regeneration Effects 0.000 description 3 ...
https://patents.google.com/patent/US20080140094
Publications | Max Planck Institute of Colloids and Interfaces
Ressnig, D.: The preparative decomposition of semi-organic crystals: metal carbodiimides become functional. Dissertation, ... Photochemical and electrocatalytic water oxidation activity of cobalt carbodiimide. Journal of Materials Chemistry A 3 (9), pp ...
https://www.mpikg.mpg.de/publication-search/5205797?person=%2Fpersons%2Fresource%2Fpersons121767
VIP Rabbit Polyclonal Antibody - 20077 | OriGeneVIP Rabbit Polyclonal Antibody - 20077 | OriGene
Porcine VIP coupled to bovine thyroglobulin (BTg) with carbodiimide (CDI) linker.. Formulation. State: Serum. State: ...
https://www.origene.com/catalog/antibodies/primary-antibodies/20077/vip-rabbit-polyclonal-antibody
US Patent Application for Quantum Dots in Modular Nucleic Acid Scaffolds Operable as Nanoscale Energy Harvesting and Focusing...US Patent Application for Quantum Dots in Modular Nucleic Acid Scaffolds Operable as Nanoscale Energy Harvesting and Focusing...
... carboxyl-amine amide bond formation by carbodiimide chemistry; (e) azide-alkyne cycloaddition; and (f) electrostatic binding, ...
https://patents.justia.com/patent/20180230522
Relevance of fiber integrated gelatin-nanohydroxyapatite composite scaffold for bone tissue regeneration - Amrita Vishwa...Relevance of fiber integrated gelatin-nanohydroxyapatite composite scaffold for bone tissue regeneration - Amrita Vishwa...
Furthermore, the treatment of PLLA fibers with 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide enhanced their hydrophilicity, ...
https://www.amrita.edu/publication/relevance-of-fiber-integrated-gelatin-nanohydroxyapatite-composite-scaffold-for-bone-tissue-regeneration/
IN VIVO IMAGING AGENTS - HAMMERSMITH IMANET LIMITEDIN VIVO IMAGING AGENTS - HAMMERSMITH IMANET LIMITED
1-ethyl-(3-dimethyl-amino-propyl)carbodiimide hydrochloride anhydrous] (EDCI, 24.5 g, 1.2 eq) was then added, and the resulting ... 1-ethyl-(3-dimethyl-aminopropyl)carbodiimide hydrochloride anhydrous] (EDCI, 5 g, 1.2 eq) was then added. The resulting mixture ...
https://www.freepatentsonline.com/y2013/0129626.html
Publications - Professor Julian JonesPublications - Professor Julian Jones
Bifidobacterium bifidum agent in tumour treatment | IJNBifidobacterium bifidum agent in tumour treatment | IJN
AP was conjugated to the surface of PFH/PLGA NPs according to a carbodiimide method. The prepared PFH/PLGA NPs (10 mg) was ... Methods: We synthesized AP-PFH/PLGA NPs using double emulsion method and carbodiimide method. Then, we evaluated targeting ... Specifically, we successfully synthesized AP-PFH/PLGA NPs using double emulsion method and carbodiimide method. The elaborately ... Shanghai, China). 1-ethyl-3- (3-dimethylaminopropyl) carbodiimide hydrochloride (EDC), N-hydroxysulfosuccinimide (sulfo-NHS), ...
https://www.dovepress.com/bifidobacterium-bifidum-mediated-specific-delivery-of-nanoparticles-fo-peer-reviewed-fulltext-article-IJN
Structural basis for microtubule recognition by the human kinetochore Ska complex | Nature CommunicationsStructural basis for microtubule recognition by the human kinetochore Ska complex | Nature Communications
For this purpose, we crosslinked the Ska1-MTBD/Ska complex with MTs, using 1-ethyl-3-[3-dimethylaminopropyl] carbodiimide ...
https://www.nature.com/articles/ncomms3964
ReagentsAmideChemistrySynthesisHydrochlorideIminesDicyclohexylcarbodiimideUreaReagentCarboxylicCrosslinkerReactionDimethylaminoAminoIsocyanatesReactThioLiquidsTransientAcidBovineCrystalsStableFormationWaterGiveMethodEffectChemicalControlAgents
Reagents4
  • Carbodiimides are reagents for the Moffatt oxidation, a protocol for conversion of an alcohol to a carbonyl (ketone or aldehyde) using dimethyl sulfoxide as the oxidizing agent: (CH3)2SO + (CyN)2C + R2CHOH → (CH3)2S + (CyNH)2CO + R2C=O Typically the sulfoxide and diimide are used in excess. (wikipedia.org)
  • There are many different types of peptide coupling reagents (e.g., carbodiimides, aminium/uranium salts, and phosphonium salts). (bloodraynebetrayal.com)
  • 2-(Alkoxycarbonyl)cycloimmonium N-aminides are efficient 1,4-dipoles that react with different types of reagents such as carbodiimides, benzoyliso(thio)cyanates and heterocyclic imidoyl chlorides to give new heterobetaines containing fused [l,2,4]triazinium systems. (uah.es)
  • Luxembourg Bio Technologies supplies the most popular and effective coupling reagents on the market, including carbodiimides and phosphonium and iminium salts. (luxembourg-bio.com)
Amide3
  • The formation of an amide using a carbodiimide is a common reaction, but carries the risk of several side reactions. (wikipedia.org)
  • Super-paramagnetic beads (SPMB)s used for a variety of molecular diagnostic assays are prepared by attaching pre-synthesized oligonucleotides to the surface via a cumbersome and low efficient method of carbodiimide-mediated amide bond formation. (mysciencework.com)
  • The amide bond was found to form efficiently via the n-hydroxysuccinimide (NHS) ester chlorin derivative, and standard coupling techniques of 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDCI), and 4-dimethylaminopyridine (DMAP) were used in the linker synthesis. (wwu.edu)
Chemistry8
  • In organic chemistry, a carbodiimide (systematic IUPAC name: methanediimine) is a functional group with the formula RN=C=NR. They are exclusively synthetic. (wikipedia.org)
  • with IL-10 protein by carbodiimide crosslinker chemistry. (immune-source.com)
  • and covalent conjugation of Ag-PVP-COOH with recombinant mouse IL-10 using EDC/NHS (1-ethyl-3-(3-dimethylaminopropyl) carbodiimide and N-Hydroxysuccinimide) chemistry. (immune-source.com)
  • Carbodiimide Modified MDI - BASF uses carbodiimide chemistry to modify and stabilize the monomeric diphenylmethane diisocyanate. (azeliscanada.com)
  • Methods Carbodiimide chemistry was employed to conjugate 1,3-β-glucan and rhodamine to PLGA. (nwu.ac.za)
  • Carbodiimide chemistry allows rapid formation of stable bonds to minimize ligand leaching. (cytivalifesciences.com)
  • After preparation of PCDH/PCDH-COOH (9/1, m/m) mixed micelles, Annexin V was coupled with the micelles using carbodiimide chemistry. (ithera-medical.com)
  • At first, we developed a surface modified PMMA microfluidic microplate, where the protein was covalently bound either to the carboxylated PMMA surface using carbodiimide chemistry or to the amine dense PMMA surface functionalized with polylysine. (utep.edu)
Synthesis5
  • A well known carbodiimide is dicyclohexylcarbodiimide, which is used in peptide synthesis. (wikipedia.org)
  • In organic synthesis, compounds containing the carbodiimide functionality are used as dehydration agents. (wikipedia.org)
  • A carbodiimide that is used as a chemical intermediate and coupling agent in peptide synthesis. (jefferson.edu)
  • In this study, we synthesized the FCC system using carbodiimide synthesis. (esmo.org)
  • Figure 1: The schematic reaction mechanism for the synthesis of polyphenol-polysaccharide conjugates by (a) 1-ethyl-3-(3-dimethylamino-propyl) carbodiimide (EDC)-mediated, (b) enzyme-mediated, and (c). (rodlike.com)
Hydrochloride5
  • A cross-linked porous silk fibroin (SF) material was prepared by freeze-drying.1-ethyl-3- (3-dimethylaminopropyl) carbodiimide hydrochloride (EDC), N- hydroxysuccinimide (NHS) and 2-morpholinoethanesulfonic acid (MES) were added in different concentrations of SF solutions. (global-sci.com)
  • 98%), 3\mercaptopropionic acidity (MPA), N\hydroxysuccinimide (NHS), and 1\ethyl\3\(3\dimethylaminopropyl) carbodiimide hydrochloride (EDC) were purchased from Sigma\Aldrich. (bioinf.org)
  • 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride. (elsevier.com)
  • The produced nanofibrous mats were crosslinked with 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride and N-hydroxysulfosuccinimide. (uludag.edu.tr)
  • Silver nanoparticles (AgNPs) encapsulated in positively charged polyethyleneimine (PEI) were reacted with an oxygen plasma modified polysulfone UF membrane with and without 1-ethyl-3-(3- dimethylaminopropyl) carbodiimide hydrochloride (EDC) present. (edu.sa)
Imines1
  • Although such compounds are extremely rare they are often implicated in industrially relevant transformations including the metathesis of imines, aldehydes and carbodiimides and group transfer reactions. (uleth.ca)
Dicyclohexylcarbodiimide1
  • DCC (acronym for N,N'-dicyclohexylcarbodiimide) was one of the first carbodiimides developed as a reagent. (wikipedia.org)
Urea1
  • Motor-3 can harvest the energy by converting this carbodiimide to urea. (rug.nl)
Reagent3
  • A typical reagent for this process is mercuric oxide: (R(H)N)2CS + HgO → (RN)2C + HgS + H2O This reaction can often be conducted as stated, even though carbodiimides react with water. (wikipedia.org)
  • Studies with substrate analogues and the pH optimum indicated the involvement of carboxyl group in the active site of goat carboxypeptidase A. Chemical modification of the enzyme with 1-cyclohexyl-3-(2-morpholinoethyl) carbodiimide methoI -p-toluene sulphonate, a carboxyl specific reagent, led to loss of both esterase and peptidase activities. (who.int)
  • Kinetic studies also confirmed the involvement of carboxylic group because the enzyme modification with water soluble carbodiimide was a two step reaction which excluded the possibility of tyrosine or lysine which are known to give a one step reaction with this reagent. (who.int)
Carboxylic5
  • The acid 1 will react with the carbodiimide to produce the key intermediate: the O-acylisourea 2, which can be viewed as a carboxylic ester with an activated leaving group. (wikipedia.org)
  • The carboxylic acid can be activated with carbodiimides (e. g. (lumiprobe.com)
  • New acidic chain termini were observed by carbodiimide-mediated amidation of carboxylic acids as anilides of gluconic, arabinonic, and erythronic acids. (ethz.ch)
  • Free carboxylic acid functions of POE are then activated by a NHS:EDC solution (NHS = N-Hydroxysuccinimide, EDC = 1-ethyl-3- (3-dimethylaminopropyl) carbodiimide). (horiba.com)
  • More recently, the ability to efficiently prepare amides from carboxylic acids via commercially available activating agents immobilized on polystyrene and silica gel supports (e.g. 1-hydroxybenzotriazole (HOBt), dichlorotriazine (DCT), carbodiimide) expands the synthetic chemist's SPOC toolbox. (auroraanalytics.com)
Crosslinker1
Reaction2
  • Isocyanates can be converted to carbodiimides with loss of carbon dioxide: 2 RN=C=O → (RN)2C + CO2 The reaction is catalyzed by phosphine oxides. (wikipedia.org)
  • Selective modification of aspartic acid-101 in lysozyme by carbodiimide reaction. (supp.ai)
Dimethylamino2
  • The aspartate was subsequently labeled with the N-cyclohexyl-N'-(4-(dimethylamino)naphthyl)carbodiimide (NCD-4) fluorophore, whereas tryptophan is autofluorescent. (cdc.gov)
  • To address this issue, we examined in more detail the CYP3A4-UGT2B7 association by means of immunoprecipitation, overlay assay, and cross-linking involving 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide. (aspetjournals.org)
Amino1
  • After removing the orthogonal protection, a carbodiimide mediated lactamization, involving the ε-amino group of lysine and γ-carboxy group of aspartic acid, led to a cyclic intermediate. (peptidepros.net)
Isocyanates1
  • Phosphorus-based catalysts are used for the production of carbodiimides from isocyanates. (factmr.com)
React1
  • Compared to other heteroallenes, carbodiimides are very weak electrophiles and only react with nucleophiles in the presence of catalysts, such as acids. (wikipedia.org)
Thio1
  • Taking advantage of our accumulated technology over a long time, we are developing various kinds of Thio compounds, Azide compounds, Tetrazoles and Carbodiimides. (toyobo-global.com)
Liquids2
  • Some diaryl derivatives tend to convert to dimers and polymers upon standing at room temperature, though this mostly occurs with low melting point carbodiimides that are liquids at room temperature. (wikipedia.org)
  • The carbodiimide-modified MDIs are liquids that are stable and clear at room temperature. (azeliscanada.com)
Transient2
  • In this work, we describe two macrocyclic diacids that, on treatment with carbodiimides, give transient macrobicyclic cages analogous to polyether cages. (miamioh.edu)
  • A 2nd generation PN 3 P-pincer azido nickel complex (PN 3 P)Ni(N 3 ) reacts with isocyanides to afford monosubstituted carbodiimides under irradiation, presumably via a transient nitrido intermediate. (edu.sa)
Acid3
  • Immunohistochemistry of carbodiimide fixed spleen revealed a dramatic increase in the number of quinolinic acid-positive cells in the red pulp in the immune-stimulated animals. (fujita-hu.ac.jp)
  • Poly(methyl methacrylate-acrylic acid) microspheres were prepared and the acid groups were activated by using either carbodiimide (CDI) or thionyl chloride (SOCl2). (metu.edu.tr)
  • The terminal propionic acid moiety can be coupled directly to free amines using EDC or another carbodiimide. (quantabiodesign.com)
Bovine2
  • Porcine VIP coupled to bovine thyroglobulin (BTg) with carbodiimide (CDI) linker. (origene.com)
  • A mixture of the desired enzyme, bovine serum albumin (BSA) and arginine were reacted with carbodiimide to formstable hydrogels. (ias.ac.in)
Crystals2
  • The preparative decomposition of semi-organic crystals: metal carbodiimides become functional. (mpg.de)
  • To preserve the cysteines of the CJ Greg crystals, crosslinking is conducted using 1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC). (csubiomod.com)
Stable1
  • Solid diaryl carbodiimides are more stable, but can slowly undergo hydrolysis in the presence of water over time. (wikipedia.org)
Formation1
  • Reacting it with a carbodiimide as fuel (pictured below), constant intramolecular anhydride formation between the rings and hydrolysis of the anhydride occur. (chemistryviews.org)
Water2
  • Photochemical and electrocatalytic water oxidation activity of cobalt carbodiimide. (mpg.de)
  • First, carboxymethyl b-cyclodextrin (CM b-CD) was grafted onto carboxymethyl chitosan (CMC) using water-soluble 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) and N-hydroxysuccinimide (NHS) as the condensing agents. (coek.info)
Give1
  • As weak bases, carbodiimides bind to Lewis acids to give adducts. (wikipedia.org)
Method2
  • We synthesized AP-PFH/PLGA NPs using double emulsion method and carbodiimide method. (dovepress.com)
  • An alternative method to pre-activating ribonucleotides was investigated by using a carbodiimide to activate ribonucleotides in situ. (rpi.edu)
Effect1
  • The Anti-calcification Effect of Dithiobispropionimidate, Carbodiimide and Ultraviolet Irradiation C. (jchestsurg.org)
Chemical1
  • We have engineered and isolated ALC Pegylated Mono both from the chemical bioconjugate carbodiimide indirect or direct AU-S binding. (electroforese.com)
Control2
  • Our group, which includes Population Services International (PSI), conducted a survey to evaluate malaria prevalence in Haiti during December 2014-February 2015 as part of the malaria control activities supported by the Global Fund- ( https://www.theglobalfund.org/en/malaria/ ). (cdc.gov)
  • This results in directional control, such that the catalysis of the carbodiimide hydration by the motor molecule continuously results in a net directional rotation about the N-C bond. (chemistryviews.org)
Agents1
  • The dehydration of N,N'-dialkylureas gives carbodiimides: (R(H)N)2CO → (RN)2C + H2O Phosphorus pentoxide and p-Toluenesulfonyl chloride have been used as a dehydrating agents. (wikipedia.org)
RTECS:GS5950000 - Cyanamide - The Registry of Toxic Effects of Chemical Substances | CDC/NIOSH
RTECS:GS5950000 - Cyanamide - The Registry of Toxic Effects of Chemical Substances | CDC/NIOSH (cdc.gov)
New molecular motor runs on chemical fuel | Science Linx News | Science LinX | University of Groningen
New molecular motor runs on chemical fuel | Science Linx News | Science LinX | University of Groningen (rug.nl)
Hydroamination of Alkenes and Alkynes with Group 2 Centred Catalysts - Research output - the University of Bath's research...
Hydroamination of Alkenes and Alkynes with Group 2 Centred Catalysts - Research output - the University of Bath's research... (researchportal.bath.ac.uk)
Structural basis for microtubule recognition by the human kinetochore Ska complex | Nature Communications
Structural basis for microtubule recognition by the human kinetochore Ska complex | Nature Communications (nature.com)
The Effect of surface modification on gliding ability of decellularized flexor tendon in a canine model in vitro - Fingerprint ...
The Effect of surface modification on gliding ability of decellularized flexor tendon in a canine model in vitro - Fingerprint ... (mayoclinic.pure.elsevier.com)
Publications | Max Planck Institute of Colloids and Interfaces
Publications | Max Planck Institute of Colloids and Interfaces (mpikg.mpg.de)
VIP Rabbit Polyclonal Antibody - 20077 | OriGene
VIP Rabbit Polyclonal Antibody - 20077 | OriGene (origene.com)
Publications - Professor Julian Jones
Publications - Professor Julian Jones (imperial.ac.uk)
Bifidobacterium bifidum agent in tumour treatment | IJN
Bifidobacterium bifidum agent in tumour treatment | IJN (dovepress.com)
KYLE BENSON
KYLE BENSON (ias.ac.in)
Cyclization of 2′-Nitrobiphenyl-2-carboxylic Acids - ScienceOpen
Cyclization of 2′-Nitrobiphenyl-2-carboxylic Acids - ScienceOpen (scienceopen.com)
Franklin Tay - Faculty Profile
Franklin Tay - Faculty Profile (augusta.edu)
BJOC - Recyclable hypervalent-iodine-mediated solid-phase peptide synthesis and cyclic peptide synthesis
BJOC - Recyclable hypervalent-iodine-mediated solid-phase peptide synthesis and cyclic peptide synthesis (beilstein-journals.org)
CXL: The Missing Link?
CXL: The Missing Link? (reviewofoptometry.com)
C-diGMP BIOLOG Life Science Institute
C-diGMP BIOLOG Life Science Institute (biolog.de)
Advances in Hybrid Polymer-Based Materials for Sustained Drug Release
Advances in Hybrid Polymer-Based Materials for Sustained Drug Release (hindawi.com)
Find Research outputs - Augusta University Research Profiles
Find Research outputs - Augusta University Research Profiles (augusta.pure.elsevier.com)
MUC1 expression and anti-MUC1 serum immune response in head and neck squamous cell carcinoma (HNSCC): a multivariate analysis |...
MUC1 expression and anti-MUC1 serum immune response in head and neck squamous cell carcinoma (HNSCC): a multivariate analysis |... (bmccancer.biomedcentral.com)
Find Research outputs - University of the Highlands and Islands
Find Research outputs - University of the Highlands and Islands (pure.uhi.ac.uk)
Development of a sensitive trial-ready poly(GP) CSF biomarker assay for C9orf72-associated frontotemporal dementia and...
Development of a sensitive trial-ready poly(GP) CSF biomarker assay for C9orf72-associated frontotemporal dementia and... (jnnp.bmj.com)
Publications - Nader Pourmand - Page 1 - MyScienceWork
Publications - Nader Pourmand - Page 1 - MyScienceWork (mysciencework.com)
Western CEDAR - Scholars Week: Efficient deprotection and demetallation of a chlorin photosensitizer followed by microwave...
Western CEDAR - Scholars Week: Efficient deprotection and demetallation of a chlorin photosensitizer followed by microwave... (cedar.wwu.edu)
Items where Division is Dietrich School of Arts and Sciences | Chemistry and Year is 2007 - D-Scholarship@Pitt
Items where Division is "Dietrich School of Arts and Sciences | Chemistry" and Year is 2007 - [email protected] (d-scholarship.pitt.edu)
Earliest known life forms - Wikipedia
Earliest known life forms - Wikipedia (en.wikipedia.org)
Cyanamide | Profiles RNS
Cyanamide | Profiles RNS (profiles.ouhsc.edu)
2-(Dibromomethyl)-4-fluorobenzonitrile
2-(Dibromomethyl)-4-fluorobenzonitrile (sincopharmachem.com)
Quinolinic acid immunoreactive cells in the choroid plexus, leptomeninges and brain vasculature of the immune-stimulated gerbil...
Quinolinic acid immunoreactive cells in the choroid plexus, leptomeninges and brain vasculature of the immune-stimulated gerbil... (pure.fujita-hu.ac.jp)